| Year |
Citation |
Score |
| 2023 |
Faber EB, Wang N, John K, Sun L, Wong HL, Burban D, Francis R, Tian D, Hong KH, Yang A, Wang L, Elsaid M, Khalid H, Levinson NM, Schönbrunn E, et al. Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of Medicinal Chemistry. PMID 36701569 DOI: 10.1021/acs.jmedchem.2c01731 |
0.475 |
|
| 2021 |
Lee JC, Hong KH, Becker A, Tash JS, Schönbrunn E, Georg GI. Tetrahydroindazole inhibitors of CDK2/cyclin complexes. European Journal of Medicinal Chemistry. 214: 113232. PMID 33550184 DOI: 10.1016/j.ejmech.2021.113232 |
0.462 |
|
| 2020 |
Zhou Y, Hu Y, Lu X, Yang H, Li Q, Du C, Chen Y, Hong KH, Sun H. Discovery of a Selective 6-Hydroxy-1, 4-Diazepan-2-one Containing Butyrylcholinesterase Inhibitor by Virtual Screening and MM-GBSA Rescoring. Dose-Response : a Publication of International Hormesis Society. 18: 1559325820938526. PMID 32636723 DOI: 10.1177/1559325820938526 |
0.379 |
|
| 2020 |
Syeda SS, Sánchez G, McDermott JP, Hong KH, Blanco G, Georg GI. The Na+ and K+ transport system of sperm (ATP1A4) is essential for male fertility and an attractive target for male contraception†. Biology of Reproduction. PMID 32588885 DOI: 10.1093/Biolre/Ioaa093 |
0.447 |
|
| 2019 |
Wang Y, Yang Y, Hong KH, Ning Y, Yu P, Ren J, Ji M, Cai J. Design, synthesis and evaluation of a novel metal chelator as multifunctional agents for the treatment of Alzheimer's disease. Bioorganic Chemistry. 87: 720-727. PMID 30954836 DOI: 10.1016/J.Bioorg.2019.03.064 |
0.387 |
|
| 2018 |
Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 30448234 DOI: 10.1016/J.Bmcl.2018.11.024 |
0.389 |
|
| 2018 |
Zhou B, Hong KH, Ji M, Cai J. Design, Synthesis and Biological Evaluation of Structurally Constrained Hybrid Analogues Containing Ropinirole Moiety as a Novel Class of Potent and Selective Dopamine D3 Receptor Ligands. Chemical Biology & Drug Design. PMID 29710404 DOI: 10.1111/Cbdd.13324 |
0.333 |
|
| 2018 |
Syeda SS, Sánchez G, Hong KH, Hawkinson JE, Georg GI, Blanco G. Design, Synthesis, in vitro and in vivo Evaluation of Ouabain Analogs as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception. Journal of Medicinal Chemistry. PMID 29291372 DOI: 10.1021/Acs.Jmedchem.7B00925 |
0.472 |
|
| 2017 |
Chen Y, Zhu JY, Hong KH, Mikles DC, Georg GI, Goldstein AS, Amory JK, Schönbrunn E. Structural basis of ALDH1A2 inhibition by irreversible and reversible small molecule inhibitors. Acs Chemical Biology. PMID 29240402 DOI: 10.1021/Acschembio.7B00685 |
0.515 |
|
| 2017 |
Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties. European Journal of Medicinal Chemistry. 134: 110-118. PMID 28410492 DOI: 10.1016/J.Ejmech.2017.04.011 |
0.419 |
|
| 2016 |
Ranade AR, Higgins L, Markowski TW, Glaser N, Kashin D, Bai R, Hong KH, Hamel E, Höfle G, Georg GI. Characterizing the Epothilone Binding Site on β-Tubulin by Photoaffinity Labeling: Identification of β-Tubulin Peptides TARGSQQY and TSRGSQQY as Targets of an Epothilone Photoprobe for Polymerized Tubulin. Journal of Medicinal Chemistry. PMID 26986898 DOI: 10.1021/Acs.Jmedchem.6B00188 |
0.44 |
|
| 2015 |
Cai J, Wei H, Hong KH, Wu X, Zong X, Cao M, Wang P, Li L, Sun C, Chen B, Zhou G, Chen J, Ji M. Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents. Bioorganic & Medicinal Chemistry. 23: 3457-71. PMID 25953722 DOI: 10.1016/J.Bmc.2015.04.028 |
0.427 |
|
| 2015 |
Cai J, Wei H, Hong KH, Wu X, Cao M, Zong X, Li L, Sun C, Chen J, Ji M. Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors. European Journal of Medicinal Chemistry. 96: 1-13. PMID 25874326 DOI: 10.1016/J.Ejmech.2015.04.002 |
0.424 |
|
| 2015 |
Cai J, Liu L, Hong KH, Wang P, Li L, Cao M, Sun C, Wu X, Zong X, Chen J, Ji M. Discovery of phenoxybutanoic acid derivatives as potent endothelin antagonists with antihypertensive activity. Bioorganic & Medicinal Chemistry. 23: 657-67. PMID 25614116 DOI: 10.1016/J.Bmc.2015.01.003 |
0.357 |
|
| 2014 |
Cai J, Li L, Hong KH, Wu X, Chen J, Wang P, Cao M, Zong X, Ji M. Discovery of 4-aminoquinazoline--urea derivatives as Aurora kinase inhibitors with antiproliferative activity. Bioorganic & Medicinal Chemistry. 22: 5813-23. PMID 25270403 DOI: 10.1016/J.Bmc.2014.09.029 |
0.418 |
|
| 2012 |
Niphakis MJ, Gay BC, Hong KH, Bleeker NP, Georg GI. Synthesis and evaluation of the anti-proliferative and NF-κB activities of a library of simplified tylophorine analogs. Bioorganic & Medicinal Chemistry. 20: 5893-900. PMID 22910225 DOI: 10.1016/J.Bmc.2012.07.044 |
0.542 |
|
| 2006 |
Duvvuri M, Konkar S, Hong KH, Blagg BS, Krise JP. A new approach for enhancing differential selectivity of drugs to cancer cells. Acs Chemical Biology. 1: 309-15. PMID 17163760 DOI: 10.1021/Cb6001202 |
0.355 |
|
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