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Dervla O'Malley - Publications

Affiliations: 
UCC, Portales, NM, United States 
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Aigbologa J, Connolly M, Buckley JM, O'Malley D. Mucosal Tuft Cell Density Is Increased in Diarrhea-Predominant Irritable Bowel Syndrome Colonic Biopsies. Frontiers in Psychiatry. 11: 436. PMID 32477197 DOI: 10.3389/fpsyt.2020.00436  0.411
2020 Stephenson KA, Rae MG, O'Malley D. Interleukin-6: A neuro-active cytokine contributing to cognitive impairment in Duchenne muscular dystrophy? Cytokine. 133: 155134. PMID 32454436 DOI: 10.1016/j.cyto.2020.155134  0.36
2019 O'Brien R, O'Malley D. The Glucagon-like peptide-1 receptor agonist, exendin-4, ameliorated gastrointestinal dysfunction in the Wistar Kyoto rat model of Irritable Bowel Syndrome. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13738. PMID 31602785 DOI: 10.1111/nmo.13738  0.371
2019 Buckley MM, O'Brien R, Buckley JM, O'Malley D. GHSR-1 agonist sensitizes rat colonic intrinsic and extrinsic neurons to exendin-4: A role in the manifestation of postprandial gastrointestinal symptoms in irritable bowel syndrome? Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13684. PMID 31311066 DOI: 10.1111/nmo.13684  0.403
2019 O'Brien R, Buckley MM, Kelliher A, O'Malley D. PI 3-kinase- and ERK-MAPK-dependent mechanisms underlie Glucagon-Like Peptide-1-mediated activation of Sprague Dawley colonic myenteric neurons. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13631. PMID 31121089 DOI: 10.1111/nmo.13631  0.419
2018 O'Malley D. Endocrine regulation of gut function - a role for glucagon-like peptide-1 in the pathophysiology of irritable bowel syndrome. Experimental Physiology. PMID 30444291 DOI: 10.1113/EP087443  0.339
2016 O'Malley D. Neuro-endocrine and neuro-immune pathways contribute to the pathophysiology of irritable bowel syndrome. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00272.2016. PMID 27742703 DOI: 10.1152/ajpgi.00272.2016  0.354
2016 Buckley MM, O'Brien R, Devlin M, Creed AA, Rae MG, Hyland NP, Quigley EM, McKernan DP, O'Malley D. Leptin modifies the pro-secretory and pro-kinetic effects of the inflammatory cytokine, interleukin-6 on colonic function in Sprague Dawley rats. Experimental Physiology. PMID 27676233 DOI: 10.1113/EP085917  0.656
2016 Manning J, Buckley MM, O'Halloran KD, O'Malley D. In vivo neutralization of IL-6 receptors ameliorates gastrointestinal dysfunction in dystrophin-deficient mdx mice. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. PMID 26920808 DOI: 10.1111/Nmo.12803  0.335
2015 O'Malley D. Immunomodulation of enteric neural function in irritable bowel syndrome. World Journal of Gastroenterology. 21: 7362-6. PMID 26139983 DOI: 10.3748/wjg.v21.i24.7362  0.304
2015 Hyland NP, O'Mahony SM, O'Malley D, O'Mahony CM, Dinan TG, Cryan JF. Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 27: 105-13. PMID 25443141 DOI: 10.1111/nmo.12486  0.701
2015 O'Malley D, Buckley MM, McKernan DP, Quigley EM, Cryan JF, Dinan TG. Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons. Brain, Behavior, and Immunity. 44: 57-67. PMID 25150006 DOI: 10.1016/j.bbi.2014.08.005  0.518
2014 Buckley MM, O'Halloran KD, Rae MG, Dinan TG, O'Malley D. Modulation of enteric neurons by interleukin-6 and corticotropin-releasing factor contributes to visceral hypersensitivity and altered colonic motility in a rat model of irritable bowel syndrome. The Journal of Physiology. 592: 5235-50. PMID 25260633 DOI: 10.1113/Jphysiol.2014.279968  0.488
2014 Buckley MM, O'Mahony SM, O'Malley D. Convergence of neuro-endocrine-immune pathways in the pathophysiology of irritable bowel syndrome. World Journal of Gastroenterology : Wjg. 20: 8846-58. PMID 25083058 DOI: 10.3748/wjg.v20.i27.8846  0.553
2014 O'Malley D, Julio-Piepera M, Dinan TG, Cryan JF. Strain differences in stress-induced changes in central CRF1 receptor expression. Neuroscience Letters. 561: 192-7. PMID 24406148 DOI: 10.1016/j.neulet.2013.12.065  0.464
2014 O'Malley D, Julio-Pieper M, O'Mahony SM, Dinan TG, Cryan JF. Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains. Experimental Physiology. 99: 359-67. PMID 24243837 DOI: 10.1113/expphysiol.2013.076109  0.649
2013 O'Malley D, Cryan JF, Dinan TG. Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion. Brain, Behavior, and Immunity. 30: 115-24. PMID 23369733 DOI: 10.1016/j.bbi.2013.01.078  0.51
2013 Buckley M, O'Malley D. Tu2102 Inhibition of Interleukin-6 Signalling Suppresses Visceral Pain Sensitivity and Stress-Induced Defecation in the Wistar Kyoto Rat Model of IBS Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63457-5  0.365
2012 O'Malley D, Dinan TG, Cryan JF. Interleukin-6 modulates colonic transepithelial ion transport in the stress-sensitive wistar kyoto rat. Frontiers in Pharmacology. 3: 190. PMID 23162465 DOI: 10.3389/fphar.2012.00190  0.493
2011 O'Malley D, Dinan TG, Cryan JF. Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction. Journal of Neuroimmunology. 235: 48-55. PMID 21565410 DOI: 10.1016/j.jneuroim.2011.04.003  0.539
2011 O'Malley D, Quigley EM, Dinan TG, Cryan JF. Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome? Brain, Behavior, and Immunity. 25: 1333-41. PMID 21536124 DOI: 10.1016/j.bbi.2011.04.009  0.522
2011 O'Malley D, Liston M, Hyland NP, Dinan TG, Cryan JF. Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G241-52. PMID 21109592 DOI: 10.1152/ajpgi.00385.2010  0.684
2011 O'Malley D, Dinan TG, Cryan JF. Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood. Psychopharmacology. 214: 221-9. PMID 20499051 DOI: 10.1007/s00213-010-1885-9  0.462
2011 O'Malley D, Quigley EM, Cryan JF, Dinan TG. Plasma From Patients With Irritable Bowel Syndrome Excites Rat Submucosal Neurons via IL-6 and CRF1 Receptor Dependent Mechanisms Gastroenterology. 140: S-835. DOI: 10.1016/S0016-5085(11)63463-X  0.526
2011 Moloney G, Fanning A, O'Malley D, Scanlan N, Cryan JF, Dinan TG, Shanahan F, Quigley EM, Melgar S, Nally K. Stimulation of T-Cells in Irritable Bowel Syndrome (IBS) Mucosal Biopsy Tissue Releases Cytokines Which Selectively Activate Submucosal Neurons Gastroenterology. 140: S-129. DOI: 10.1016/S0016-5085(11)60526-X  0.469
2010 O'Malley D, Julio-Pieper M, Gibney SM, Dinan TG, Cryan JF. Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour. Stress (Amsterdam, Netherlands). 13: 114-22. PMID 20214436 DOI: 10.3109/10253890903067418  0.553
2010 O'Malley D, Dinan TG, Cryan JF. Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: differential effects of acute psychological and physical stressors. Peptides. 31: 662-70. PMID 20096320 DOI: 10.1016/j.peptides.2010.01.004  0.474
2010 o'malley D, Julio-Pieper M, Gibney SM, Gosselin RD, Dinan TG, Cryan JF. Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 301-11. PMID 19807869 DOI: 10.1111/j.1365-2982.2009.01412.x  0.67
2010 O'Malley D, Liston M, Dinan TG, Cryan JF, Hyland NP. T1753 CRF1 Receptor-Dependent Activation of Submucosal Neurones by Colonic Supernatants From Maternally Separated Rats Gastroenterology. 138: S-571. DOI: 10.1016/S0016-5085(10)62631-5  0.658
2009 Gosselin RD, Gibney S, O'Malley D, Dinan TG, Cryan JF. Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression. Neuroscience. 159: 915-25. PMID 19000745 DOI: 10.1016/j.neuroscience.2008.10.018  0.625
2005 Harvey J, Shanley LJ, O'Malley D, Irving AJ. Leptin: a potential cognitive enhancer? Biochemical Society Transactions. 33: 1029-32. PMID 16246038 DOI: 10.1042/BST20051029  0.315
2002 Shanley LJ, O'Malley D, Irving AJ, Ashford ML, Harvey J. Leptin inhibits epileptiform-like activity in rat hippocampal neurones via PI 3-kinase-driven activation of BK channels. The Journal of Physiology. 545: 933-44. PMID 12482897 DOI: 10.1113/jphysiol.2002.029488  0.322
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