Elisabeth B. Binder - Publications

Affiliations: 
Max Planck Instute of Psychiatry/Emory, München, Bayern, Germany 
Area:
Psychiatric Genetics

214 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Halldorsdottir T, Piechaczek C, Soares de Matos AP, Czamara D, Pehl V, Wagenbuechler P, Feldmann L, Quickenstedt-Reinhardt P, Allgaier AK, Freisleder FJ, Greimel E, Kvist T, Lahti J, Räikkönen K, Rex-Haffner M, ... ... Binder EB, et al. Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths. The American Journal of Psychiatry. appiajp201918091014. PMID 30947532 DOI: 10.1176/appi.ajp.2019.18091014  0.32
2019 Toepfer P, O Donnell KJ, Entringer S, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment. Journal of the American Academy of Child and Adolescent Psychiatry. PMID 30858011 DOI: 10.1016/j.jaac.2019.03.006  0.56
2019 Toepfer P, O'Donnell KJ, Entringer S, Garg E, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness. Psychoneuroendocrinology. 103: 156-162. PMID 30690225 DOI: 10.1016/j.psyneuen.2019.01.013  0.56
2018 Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study. The British Journal of Psychiatry : the Journal of Mental Science. 1-9. PMID 30457060 DOI: 10.1192/bjp.2018.234  0.4
2018 Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB. DNA methylation levels are associated with CRF receptor antagonist treatment outcome in women with post-traumatic stress disorder. Clinical Epigenetics. 10: 136. PMID 30390684 DOI: 10.1186/s13148-018-0569-x  1
2018 Kelley ME, Dunlop BW, Nemeroff CB, Lori A, Carrillo-Roa T, Binder EB, Kutner MH, Rivera VA, Craighead WE, Mayberg HS. Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse. Depression and Anxiety. PMID 30260539 DOI: 10.1002/da.22832  1
2018 Elbau IG, Brücklmeier B, Uhr M, Arloth J, Czamara D, Spoormaker VI, Czisch M, Stephan KE, Binder EB, Sämann PG. The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers. Proceedings of the National Academy of Sciences of the United States of America. PMID 30201713 DOI: 10.1073/pnas.1804340115  0.44
2018 Engel M, Eggert C, Kaplick PM, Eder M, Röh S, Tietze L, Namendorf C, Arloth J, Weber P, Rex-Haffner M, Geula S, Jakovcevski M, Hanna JH, Leshkowitz D, Uhr M, ... ... Binder EB, et al. The Role of mA/m-RNA Methylation in Stress Response Regulation. Neuron. 99: 389-403.e9. PMID 30048615 DOI: 10.1016/j.neuron.2018.07.009  0.44
2018 Mehta D, Bruenig D, Lawford B, Harvey W, Carrillo-Roa T, Morris CP, Jovanovic T, Young RM, Binder EB, Voisey J. Accelerated DNA methylation aging and increased resilience in veterans: The biological cost for soldiering on. Neurobiology of Stress. 8: 112-119. PMID 29888306 DOI: 10.1016/j.ynstr.2018.04.001  0.68
2018 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, ... ... Binder EB, et al. Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 19: 61. PMID 29792225 DOI: 10.1186/s13059-018-1441-1  1
2018 Suarez A, Lahti J, Czamara D, Lahti-Pulkkinen M, Knight AK, Girchenko P, Hämäläinen E, Kajantie E, Lipsanen J, Laivuori H, Villa PM, Reynolds RM, Smith AK, Binder EB, Räikkönen K. The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems. Journal of the American Academy of Child and Adolescent Psychiatry. 57: 321-328.e2. PMID 29706161 DOI: 10.1016/j.jaac.2018.02.011  0.68
2018 Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics. PMID 29700475 DOI: 10.1038/s41588-018-0090-3  0.4
2018 Rampp C, Eichelkraut A, Best J, Czamara D, Rex-Haffner M, Uhr M, Binder EB, Menke A. Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls. Journal of Psychiatric Research. 98: 107-115. PMID 29331929 DOI: 10.1016/j.jpsychires.2017.12.020  0.44
2018 Naik RR, Sotnikov SV, Diepold RP, Iurato S, Markt PO, Bultmann A, Brehm N, Mattheus T, Lutz B, Erhardt A, Binder EB, Schmidt U, Holsboer F, Landgraf R, Czibere L. Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex. Translational Psychiatry. 8: 1. PMID 29317594 DOI: 10.1038/s41398-017-0025-2  0.44
2017 Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, ... ... Binder EB, et al. Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. Plos Biology. 15: e2002690. PMID 29283992 DOI: 10.1371/journal.pbio.2002690  1
2017 Iurato S, Carrillo-Roa T, Arloth J, Czamara D, Diener-Hölzl L, Lange J, Müller-Myhsok B, Binder EB, Erhardt A. "DNA Methylation signatures in panic disorder". Translational Psychiatry. 7: 1287. PMID 29249830 DOI: 10.1038/s41398-017-0026-1  0.32
2017 O'Connell CP, Goldstein-Piekarski AN, Nemeroff CB, Schatzberg AF, Debattista C, Carrillo-Roa T, Binder EB, Dunlop BW, Craighead WE, Mayberg HS, Williams LM. Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein. The American Journal of Psychiatry. appiajp201717020172. PMID 29241359 DOI: 10.1176/appi.ajp.2017.17020172  1
2017 Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS. Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder. Biological Psychiatry. PMID 28793974 DOI: 10.1016/j.biopsych.2017.06.024  1
2017 Girchenko P, Lahti J, Czamara D, Knight AK, Jones MJ, Suarez A, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Kobor MS, Smith AK, Binder EB, Räikkönen K. Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth. Clinical Epigenetics. 9: 49. PMID 28503212 DOI: 10.1186/s13148-017-0349-z  0.68
2017 Girchenko P, Lahti M, Tuovinen S, Savolainen K, Lahti J, Binder EB, Reynolds RM, Entringer S, Buss C, Wadhwa PD, Hämäläinen E, Kajantie E, Pesonen AK, Villa PM, Laivuori H, et al. Cohort Profile: Prediction and prevention of preeclampsia and intrauterine growth restriction (PREDO) study. International Journal of Epidemiology. 46: 1380-1381g. PMID 27639277 DOI: 10.1093/ije/dyw154  0.56
2016 Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, ... ... Binder EB, et al. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology. 17: 255. PMID 27955697 DOI: 10.1186/s13059-016-1119-5  1
2016 Knight AK, Craig JM, Theda C, Bækvad-Hansen M, Bybjerg-Grauholm J, Hansen CS, Hollegaard MV, Hougaard DM, Mortensen PB, Weinsheimer SM, Werge TM, Brennan PA, Cubells JF, Newport DJ, Stowe ZN, ... ... Binder EB, et al. An epigenetic clock for gestational age at birth based on blood methylation data. Genome Biology. 17: 206. PMID 27717399 DOI: 10.1186/s13059-016-1068-z  0.76
2016 Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, ... ... Binder EB, et al. Epigenetic Signatures of Cigarette Smoking. Circulation. Cardiovascular Genetics. PMID 27651444 DOI: 10.1161/CIRCGENETICS.116.001506  1
2016 He Q, Cai T, Liu Y, Zhao N, Harmon QE, Almli LM, Binder EB, Engel SM, Ressler KJ, Conneely KN, Lin X, Wu MC. Prioritizing individual genetic variants after kernel machine testing using variable selection. Genetic Epidemiology. PMID 27488097 DOI: 10.1002/gepi.21993  1
2016 Andlauer TF, Buck D, Antony G, Bayas A, Bechmann L, Berthele A, Chan A, Gasperi C, Gold R, Graetz C, Haas J, Hecker M, Infante-Duarte C, Knop M, Kümpfel T, ... ... Binder EB, et al. Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Science Advances. 2: e1501678. PMID 27386562 DOI: 10.1126/sciadv.1501678  0.32
2016 Garn H, Bahn S, Baune BT, Binder EB, Bisgaard H, Chatila TA, Chavakis T, Culmsee C, Dannlowski U, Gay S, Gern J, Haahtela T, Kircher T, Müller-Ladner U, Neurath MF, et al. Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. The Journal of Allergy and Clinical Immunology. 138: 47-56. PMID 27373325 DOI: 10.1016/j.jaci.2016.02.046  0.44
2016 Menke A, Arloth J, Best J, Namendorf C, Gerlach T, Czamara D, Lucae S, Dunlop BW, Crowe TM, Garlow SJ, Nemeroff CB, Ritchie JC, Craighead WE, Mayberg HS, Rex-Haffner M, ... Binder EB, et al. Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests. Psychoneuroendocrinology. 69: 161-171. PMID 27107207 DOI: 10.1016/j.psyneuen.2016.04.003  1
2016 Houtepen LC, Vinkers CH, Carrillo-Roa T, Hiemstra M, van Lier PA, Meeus W, Branje S, Heim CM, Nemeroff CB, Mill J, Schalkwyk LC, Creyghton MP, Kahn RS, Joëls M, Binder EB, et al. Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nature Communications. 7: 10967. PMID 26997371 DOI: 10.1038/ncomms10967  1
2016 Wingo AP, Almli LM, Stevens JS, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, ... ... Binder EB, et al. Corrigendum: DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nature Communications. 7: 10958. PMID 26936533 DOI: 10.1038/ncomms10958  1
2016 Kao CY, He Z, Zannas AS, Hahn O, Kühne C, Reichel JM, Binder EB, Wotjak CT, Khaitovich P, Turck CW. Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder. Journal of Psychiatric Research. 76: 74-83. PMID 26897419 DOI: 10.1016/j.jpsychires.2016.02.003  0.44
2015 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, ... ... Binder EB, et al. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 16: 266. PMID 26673150 DOI: 10.1186/s13059-015-0828-5  1
2015 Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, ... ... Binder EB, et al. DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nature Communications. 6: 10106. PMID 26632874 DOI: 10.1038/ncomms10106  0.44
2015 Gassen NC, Fries GR, Zannas AS, Hartmann J, Zschocke J, Hafner K, Carrillo-Roa T, Steinbacher J, Preißinger SN, Hoeijmakers L, Knop M, Weber F, Kloiber S, Lucae S, Chrousos GP, ... ... Binder EB, et al. Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine. Science Signaling. 8: ra119. PMID 26602018 DOI: 10.1126/scisignal.aac7695  0.44
2015 Stephan KE, Bach DR, Fletcher PC, Flint J, Frank MJ, Friston KJ, Heinz A, Huys QJ, Owen MJ, Binder EB, Dayan P, Johnstone EC, Meyer-Lindenberg A, Montague PR, Schnyder U, et al. Charting the landscape of priority problems in psychiatry, part 1: classification and diagnosis. The Lancet. Psychiatry. PMID 26573970 DOI: 10.1016/S2215-0366(15)00361-2  0.44
2015 Stephan KE, Binder EB, Breakspear M, Dayan P, Johnstone EC, Meyer-Lindenberg A, Schnyder U, Wang XJ, Bach DR, Fletcher PC, Flint J, Frank MJ, Heinz A, Huys QJ, Montague PR, et al. Charting the landscape of priority problems in psychiatry, part 2: pathogenesis and aetiology. The Lancet. Psychiatry. PMID 26573969 DOI: 10.1016/S2215-0366(15)00360-0  0.44
2015 Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, ... ... Binder EB, et al. The transcriptional landscape of age in human peripheral blood. Nature Communications. 6: 8570. PMID 26490707 DOI: 10.1038/ncomms9570  0.44
2015 Yehuda R, Daskalakis NP, Bierer LM, Bader HN, Klengel T, Holsboer F, Binder EB. Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. Biological Psychiatry. PMID 26410355 DOI: 10.1016/j.biopsych.2015.08.005  0.44
2015 Kaminsky Z, Wilcox HC, Eaton WW, Van Eck K, Kilaru V, Jovanovic T, Klengel T, Bradley B, Binder EB, Ressler KJ, Smith AK. Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-traumatic stress disorder. Translational Psychiatry. 5: e627. PMID 26305478 DOI: 10.1038/tp.2015.105  1
2015 Zannas AS, Wiechmann T, Gassen NC, Binder EB. Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26250598 DOI: 10.1038/npp.2015.235  0.44
2015 Kohrt BA, Worthman CM, Ressler KJ, Mercer KB, Upadhaya N, Koirala S, Nepal MK, Sharma VD, Binder EB. Cross-cultural gene- environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia. International Review of Psychiatry (Abingdon, England). 27: 180-96. PMID 26100613 DOI: 10.3109/09540261.2015.1020052  1
2015 Klengel T, Binder EB. Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions. Neuron. 86: 1343-57. PMID 26087162 DOI: 10.1016/j.neuron.2015.05.036  1
2015 Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, ... ... Binder EB, et al. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron. 86: 1189-202. PMID 26050039 DOI: 10.1016/j.neuron.2015.05.034  0.44
2015 Almli LM, Stevens JS, Smith AK, Kilaru V, Meng Q, Flory J, Abu-Amara D, Hammamieh R, Yang R, Mercer KB, Binder EB, Bradley B, Hamilton S, Jett M, Yehuda R, et al. A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 327-36. PMID 25988933 DOI: 10.1002/ajmg.b.32315  1
2015 Zannas AS, Provençal N, Binder EB. Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions. Biological Psychiatry. 78: 327-35. PMID 25979620 DOI: 10.1016/j.biopsych.2015.04.003  1
2015 Peyrot WJ, Lee SH, Milaneschi Y, Abdellaoui A, Byrne EM, Esko T, de Geus EJ, Hemani G, Hottenga JJ, Kloiber S, Levinson DF, Lucae S, Martin NG, Medland SE, et al. The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects. Molecular Psychiatry. 20: 735-43. PMID 25917368 DOI: 10.1038/mp.2015.50  1
2015 Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, et al. An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress. Psychoneuroendocrinology. 57: 1-13. PMID 25867994 DOI: 10.1016/j.psyneuen.2015.03.016  1
2015 Gassen NC, Hartmann J, Zannas AS, Kretzschmar A, Zschocke J, Maccarrone G, Hafner K, Zellner A, Kollmannsberger LK, Wagner KV, Mehta D, Kloiber S, Turck CW, Lucae S, Chrousos GP, ... ... Binder EB, et al. FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications. Molecular Psychiatry. PMID 25849320 DOI: 10.1038/mp.2015.38  1
2015 Hommers L, Raab A, Bohl A, Weber H, Scholz CJ, Erhardt A, Binder E, Arolt V, Gerlach A, Gloster A, Kalisch R, Kircher T, Lonsdorf T, Ströhle A, Zwanzger P, et al. MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 296-306. PMID 25847876 DOI: 10.1002/ajmg.b.32312  1
2015 Ferentinos P, Koukounari A, Power R, Rivera M, Uher R, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Ising M, Maier W, Mors O, ... ... Binder EB, et al. Familiality and SNP heritability of age at onset and episodicity in major depressive disorder. Psychological Medicine. 1-11. PMID 25698070 DOI: 10.1017/S0033291715000215  1
2015 Binder E, Lange O, Edlinger M, Meraner D, Abt D, Moser C, Steichen E, Hofer SE. Frequency of dermatological side effects of continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 123: 260-4. PMID 25607337 DOI: 10.1055/s-0034-1394381  1
2015 Daskalakis NP, Binder EB. Schizophrenia in the spectrum of gene-stress interactions: the FKBP5 example. Schizophrenia Bulletin. 41: 323-9. PMID 25592294 DOI: 10.1093/schbul/sbu189  0.44
2015 Klengel T, Binder EB. FKBP5 allele-specific epigenetic modification in gene by environment interaction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 244-6. PMID 25482174 DOI: 10.1038/npp.2014.208  1
2015 Gaali S, Kirschner A, Cuboni S, Hartmann J, Kozany C, Balsevich G, Namendorf C, Fernandez-Vizarra P, Sippel C, Zannas AS, Draenert R, Binder EB, Almeida OF, Rühter G, Uhr M, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nature Chemical Biology. 11: 33-7. PMID 25436518 DOI: 10.1038/nchembio.1699  0.44
2015 Smith AK, Kilaru V, Klengel T, Mercer KB, Bradley B, Conneely KN, Ressler KJ, Binder EB. DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 36-44. PMID 25355443 DOI: 10.1002/ajmg.b.32278  1
2015 Jukic MM, Carrillo-Roa T, Bar M, Becker G, Jovanovic VM, Zega K, Binder EB, Brodski C. Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 839-48. PMID 25241801 DOI: 10.1038/npp.2014.244  1
2015 Provencal N, Binder EB. The neurobiological effects of stress as contributors to psychiatric disorders: focus on epigenetics. Current Opinion in Neurobiology. 30: 31-7. PMID 25218938 DOI: 10.1016/j.conb.2014.08.007  1
2015 Provençal N, Binder EB. The effects of early life stress on the epigenome: From the womb to adulthood and even before. Experimental Neurology. 268: 10-20. PMID 25218020 DOI: 10.1016/j.expneurol.2014.09.001  1
2015 Kohrt BA, Worthman CM, Ressler KJ, Mercer KB, Upadhaya N, Koirala S, Nepal MK, Sharma VD, Binder EB. Cross-cultural gene-environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia: GxE interactions in South Asia International Review of Psychiatry. 27: 180-196. DOI: 10.3109/09540261.2015.1020052  0.44
2015 Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, ... ... Binder EB, et al. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders Neuron. 86: 1189-1202. DOI: 10.1016/j.neuron.2015.05.034  1
2015 Zimmermann CA, Hoffmann A, Binder EB, Spengler D. Differences in Histone Modifications Between Individuals Personalized Epigenetics. 55-82. DOI: 10.1016/B978-0-12-420135-4.00003-6  0.44
2015 Reinauer C, Meissner T, Roden M, Thon A, Holterhus PM, Haberland H, Binder E, Marg W, Bollow E, Holl R. Low prevalence of patients with mitochondrial disease in the German/Austrian DPV diabetes registry European Journal of Pediatrics. 1-10. DOI: 10.1007/s00431-015-2675-5  1
2014 Rampp C, Binder EB, Provençal N. Epigenetics in posttraumatic stress disorder. Progress in Molecular Biology and Translational Science. 128: 29-50. PMID 25410540 DOI: 10.1016/B978-0-12-800977-2.00002-4  1
2014 Menke A, Binder EB. Epigenetic alterations in depression and antidepressant treatment. Dialogues in Clinical Neuroscience. 16: 395-404. PMID 25364288  1
2014 Almli LM, Duncan R, Feng H, Ghosh D, Binder EB, Bradley B, Ressler KJ, Conneely KN, Epstein MP. Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder. Jama Psychiatry. 71: 1392-9. PMID 25354142 DOI: 10.1001/jamapsychiatry.2014.1339  1
2014 Pape JC, Binder EB. [Psychological trauma as risk for delayed psychiatric disorders: epigenetic mechanisms]. Der Nervenarzt. 85: 1382-9. PMID 25208492 DOI: 10.1007/s00115-014-4085-8  1
2014 Sabbagh JJ, O'Leary JC, Blair LJ, Klengel T, Nordhues BA, Fontaine SN, Binder EB, Dickey CA. Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency. Plos One. 9: e107241. PMID 25191701 DOI: 10.1371/journal.pone.0107241  1
2014 Mullins N, Perroud N, Uher R, Butler AW, Cohen-Woods S, Rivera M, Malki K, Euesden J, Power RA, Tansey KE, Jones L, Jones I, Craddock N, Owen MJ, Korszun A, ... ... Binder EB, et al. Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 428-37. PMID 24964207 DOI: 10.1002/ajmg.b.32247  1
2014 Issler O, Haramati S, Paul ED, Maeno H, Navon I, Zwang R, Gil S, Mayberg HS, Dunlop BW, Menke A, Awatramani R, Binder EB, Deneris ES, Lowry CA, Chen A. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity. Neuron. 83: 344-60. PMID 24952960 DOI: 10.1016/j.neuron.2014.05.042  1
2014 Dunlop BW, Rothbaum BO, Binder EB, Duncan E, Harvey PD, Jovanovic T, Kelley ME, Kinkead B, Kutner M, Iosifescu DV, Mathew SJ, Neylan TC, Kilts CD, Nemeroff CB, Mayberg HS. Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial. Trials. 15: 240. PMID 24950747 DOI: 10.1186/1745-6215-15-240  1
2014 Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, ... ... Binder EB, et al. A polymorphism in the Crhr1 gene determines stress vulnerability in male mice. Endocrinology. 155: 2500-10. PMID 24773341 DOI: 10.1210/en.2013-1986  1
2014 Menke A, Arloth J, Gerber M, Rex-Haffner M, Uhr M, Holsboer F, Binder EB, Holsboer-Trachsler E, Beck J. Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion. Psychoneuroendocrinology. 44: 35-46. PMID 24767618 DOI: 10.1016/j.psyneuen.2014.02.013  1
2014 Schneider M, Engel A, Fasching PA, Häberle L, Binder EB, Voigt F, Grimm J, Faschingbauer F, Eichler A, Dammer U, Rebhan D, Amann M, Raabe E, Goecke TW, Quast C, et al. Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy. Biomed Research International. 2014: 469278. PMID 24741566 DOI: 10.1155/2014/469278  1
2014 Nemeroff CB, Binder E. The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders: toward elucidating the underlying neurobiological mechanisms. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 395-7. PMID 24655648 DOI: 10.1016/j.jaac.2014.02.004  1
2014 Dettmar AK, Binder E, Greiner FR, Liebau MC, Kurschat CE, Jungraithmayr TC, Saleem MA, Schmitt CP, Feifel E, Orth-Höller D, Kemper MJ, Pepys M, Würzner R, Oh J. Protection of human podocytes from shiga toxin 2-induced phosphorylation of mitogen-activated protein kinases and apoptosis by human serum amyloid P component. Infection and Immunity. 82: 1872-9. PMID 24566618 DOI: 10.1128/IAI.01591-14  1
2014 Mehta D, Newport DJ, Frishman G, Kraus L, Rex-Haffner M, Ritchie JC, Lori A, Knight BT, Stagnaro E, Ruepp A, Stowe ZN, Binder EB. Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling. Psychological Medicine. 44: 2309-22. PMID 24495551 DOI: 10.1017/S0033291713003231  1
2014 Barfield RT, Almli LM, Kilaru V, Smith AK, Mercer KB, Duncan R, Klengel T, Mehta D, Binder EB, Epstein MP, Ressler KJ, Conneely KN. Accounting for population stratification in DNA methylation studies. Genetic Epidemiology. 38: 231-41. PMID 24478250 DOI: 10.1002/gepi.21789  1
2014 Klengel T, Pape J, Binder EB, Mehta D. The role of DNA methylation in stress-related psychiatric disorders. Neuropharmacology. 80: 115-32. PMID 24452011 DOI: 10.1016/j.neuropharm.2014.01.013  1
2014 Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, ... ... Binder EB, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 8: 153-82. PMID 24399358 DOI: 10.1007/s11682-013-9269-5  1
2014 Quast C, Reif A, Brückl T, Pfister H, Weber H, Mattheisen M, Cichon S, Lang T, Hamm A, Fehm L, Ströhle A, Arolt V, Domschke K, Kircher T, Wittchen HU, ... ... Binder EB, et al. Gender-specific association of variants in the AKR1C1 gene with dimensional anxiety in patients with panic disorder: additional evidence for the importance of neurosteroids in anxiety? Depression and Anxiety. 31: 843-50. PMID 24390875 DOI: 10.1002/da.22229  1
2014 Skuse DH, Lori A, Cubells JF, Lee I, Conneely KN, Puura K, Lehtimäki T, Binder EB, Young LJ. Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills. Proceedings of the National Academy of Sciences of the United States of America. 111: 1987-92. PMID 24367110 DOI: 10.1073/pnas.1302985111  1
2014 Fani N, King TZ, Reiser E, Binder EB, Jovanovic T, Bradley B, Ressler KJ. FKBP5 genotype and structural integrity of the posterior cingulum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1206-13. PMID 24253961 DOI: 10.1038/npp.2013.322  1
2014 Zannas AS, Binder EB. Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism. Genes, Brain, and Behavior. 13: 25-37. PMID 24219237 DOI: 10.1111/gbb.12104  1
2014 Ferentinos P, Rivera M, Ising M, Spain SL, Cohen-Woods S, Butler AW, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, ... ... Binder EB, et al. Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution. Journal of Affective Disorders. 155: 81-9. PMID 24215895 DOI: 10.1016/j.jad.2013.10.027  1
2014 Schumann G, Binder EB, Holte A, de Kloet ER, Oedegaard KJ, Robbins TW, Walker-Tilley TR, Bitter I, Brown VJ, Buitelaar J, Ciccocioppo R, Cools R, Escera C, Fleischhacker W, Flor H, et al. Stratified medicine for mental disorders. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 5-50. PMID 24176673 DOI: 10.1016/j.euroneuro.2013.09.010  1
2014 Binder E, Griesmaier E, Giner T, Sailer-Höck M, Brunner J. Kawasaki disease in children and adolescents: Clinical data of Kawasaki patients in a western region (Tyrol) of Austria from 2003-2012 Pediatric Rheumatology. 12. DOI: 10.1186/1546-0096-12-37  1
2013 Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, ... Binder EB, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/JCI69003  1
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Binder EB, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/ng.2711  1
2013 Kshirsagar S, Binder E, Riedl M, Wechselberger G, Steichen E, Edelbauer M. Enhanced activity of Akt in Teff cells from children with lupus nephritis is associated with reduced induction of tumor necrosis factor receptor-associated factor 6 and increased OX40 expression. Arthritis and Rheumatism. 65: 2996-3006. PMID 23896866 DOI: 10.1002/art.38089  1
2013 Quast C, Cuboni S, Bader D, Altmann A, Weber P, Arloth J, Röh S, Brückl T, Ising M, Kopczak A, Erhardt A, Hausch F, Lucae S, Binder EB. Functional coding variants in SLC6A15, a possible risk gene for major depression. Plos One. 8: e68645. PMID 23874702 DOI: 10.1371/journal.pone.0068645  1
2013 Andero R, Brothers SP, Jovanovic T, Chen YT, Salah-Uddin H, Cameron M, Bannister TD, Almli L, Stevens JS, Bradley B, Binder EB, Wahlestedt C, Ressler KJ. Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Science Translational Medicine. 5: 188ra73. PMID 23740899 DOI: 10.1126/scitranslmed.3005656  1
2013 Sun YV, Smith AK, Conneely KN, Chang Q, Li W, Lazarus A, Smith JA, Almli LM, Binder EB, Klengel T, Cross D, Turner ST, Ressler KJ, Kardia SL. Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans. Human Genetics. 132: 1027-37. PMID 23657504 DOI: 10.1007/s00439-013-1311-6  1
2013 Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proceedings of the National Academy of Sciences of the United States of America. 110: 8302-7. PMID 23630272 DOI: 10.1073/pnas.1217750110  1
2013 Mehta D, Raison CL, Woolwine BJ, Haroon E, Binder EB, Miller AH, Felger JC. Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with treatment-resistant depression. Brain, Behavior, and Immunity. 31: 205-15. PMID 23624296 DOI: 10.1016/j.bbi.2013.04.004  1
2013 Norrholm SD, Jovanovic T, Smith AK, Binder E, Klengel T, Conneely K, Mercer KB, Davis JS, Kerley K, Winkler J, Gillespie CF, Bradley B, Ressler KJ. Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder. Frontiers in Behavioral Neuroscience. 7: 30. PMID 23596403 DOI: 10.3389/fnbeh.2013.00030  1
2013 Klengel T, Binder EB. Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stress-related psychiatric disorders? Epigenomics. 5: 109-12. PMID 23566086 DOI: 10.2217/epi.13.11  1
2013 Gillespie CF, Almli LM, Smith AK, Bradley B, Kerley K, Crain DF, Mercer KB, Weiss T, Phifer J, Tang Y, Cubells JF, Binder EB, Conneely KN, Ressler KJ. Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 283-92. PMID 23505265 DOI: 10.1002/ajmg.b.32147  1
2013 Klengel T, Binder EB. Gene-environment interactions in major depressive disorder. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 58: 76-83. PMID 23442893  1
2013 Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J, Glover E, Jovanovic T, Bradley B, Dinov ID, Zamanyan A, Toga AW, Binder EB, Ressler KJ. FKBP5 and attention bias for threat: associations with hippocampal function and shape. Jama Psychiatry. 70: 392-400. PMID 23407841 DOI: 10.1001/2013.jamapsychiatry.210  1
2013 Menke A, Klengel T, Rubel J, Brückl T, Pfister H, Lucae S, Uhr M, Holsboer F, Binder EB. Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression. Genes, Brain, and Behavior. 12: 289-96. PMID 23406438 DOI: 10.1111/gbb.12026  1
2013 Binder E, Edelbauer M. Use of biomarkers in the management of children with lupus. Current Rheumatology Reports. 15: 312. PMID 23355230 DOI: 10.1007/s11926-012-0312-0  1
2013 Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, ... ... Binder EB, et al. Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychological Medicine. 43: 1965-71. PMID 23237013 DOI: 10.1017/S0033291712002589  1
2013 Klengel T, Binder EB. Gene × environment interactions in the prediction of response to antidepressant treatment. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 701-11. PMID 23237009 DOI: 10.1017/S1461145712001459  1
2013 Jang MH, Kitabatake Y, Kang E, Jun H, Pletnikov MV, Christian KM, Hen R, Lucae S, Binder EB, Song H, Ming GI. Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans. Molecular Psychiatry. 18: 957-8. PMID 23207650 DOI: 10.1038/mp.2012.158  1
2013 Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, ... Binder EB, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nature Neuroscience. 16: 33-41. PMID 23201972 DOI: 10.1038/nn.3275  1
2013 Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, ... ... Binder E, et al. Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 653-62. PMID 23026132 DOI: 10.1016/j.euroneuro.2012.08.010  1
2013 Bourke CH, Raees MQ, Malviya S, Bradburn CA, Binder EB, Neigh GN. Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner. Psychoneuroendocrinology. 38: 84-93. PMID 22647578 DOI: 10.1016/j.psyneuen.2012.05.001  1
2013 Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, ... ... Binder EB, et al. A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry. 18: 497-511. PMID 22472876 DOI: 10.1038/mp.2012.21  0.56
2013 Uher R, Tansey KE, Rietschel M, Henigsberg N, Maier W, Mors O, Hauser J, Placentino A, Souery D, Farmer A, Aitchison KJ, Craig I, McGuffin P, Lewis CM, Ising M, ... ... Binder EB, et al. Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies American Journal of Psychiatry. 170: 207-217. DOI: 10.1176/appi.ajp.2012.12020237  1
2012 Ganea K, Menke A, Schmidt MV, Lucae S, Rammes G, Liebl C, Harbich D, Sterlemann V, Storch C, Uhr M, Holsboer F, Binder EB, Sillaber I, Müller MB. Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response. Translational Psychiatry. 2: e177. PMID 23092981 DOI: 10.1038/tp.2012.104  0.44
2012 Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Müller-Myhsok B, Mors O, Borglum A, Kristensen AS, Woldbye DP, Koefoed P, Eriksson E, Maron E, Metspalu A, Nurnberger J, ... ... Binder EB, et al. Replication and meta-analysis of TMEM132D gene variants in panic disorder. Translational Psychiatry. 2: e156. PMID 22948381 DOI: 10.1038/tp.2012.85  1
2012 Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Hauser J, ... ... Binder EB, et al. Dissecting the genetic heterogeneity of depression through age at onset. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 859-68. PMID 22915352 DOI: 10.1002/ajmg.b.32093  1
2012 Kennedy AP, Binder EB, Bowman D, Harenski K, Ely T, Cisler JM, Tripathi SP, VanNess S, Kilts CD. A common TPH2 haplotype regulates the neural processing of a cognitive control demand. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 829-40. PMID 22915309 DOI: 10.1002/ajmg.b.32090  1
2012 Quast C, Altmann A, Weber P, Arloth J, Bader D, Heck A, Pfister H, Müller-Myhsok B, Erhardt A, Binder EB. Rare variants in TMEM132D in a case-control sample for panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 896-907. PMID 22911938 DOI: 10.1002/ajmg.b.32096  1
2012 Reif A, Weber H, Domschke K, Klauke B, Baumann C, Jacob CP, Ströhle A, Gerlach AL, Alpers GW, Pauli P, Hamm A, Kircher T, Arolt V, Wittchen HU, Binder EB, et al. Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 786-93. PMID 22911667 DOI: 10.1002/ajmg.b.32085  1
2012 Altmann A, Weber P, Bader D, Preuss M, Binder EB, Müller-Myhsok B. A beginners guide to SNP calling from high-throughput DNA-sequencing data. Human Genetics. 131: 1541-54. PMID 22886560 DOI: 10.1007/s00439-012-1213-z  1
2012 Dunlop BW, Binder EB, Cubells JF, Goodman MM, Kelley ME, Kinkead B, Kutner M, Nemeroff CB, Newport DJ, Owens MJ, Pace TW, Ritchie JC, Rivera VA, Westen D, Craighead WE, et al. Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial. Trials. 13: 106. PMID 22776534 DOI: 10.1186/1745-6215-13-106  1
2012 Fasching PA, Faschingbauer F, Goecke TW, Engel A, Häberle L, Seifert A, Voigt F, Amann M, Rebhan D, Burger P, Kornhuber J, Ekici AB, Beckmann MW, Binder EB. Genetic variants in the tryptophan hydroxylase 2 gene (TPH2) and depression during and after pregnancy. Journal of Psychiatric Research. 46: 1109-17. PMID 22721547 DOI: 10.1016/j.jpsychires.2012.05.011  1
2012 Menke A, Klengel T, Binder EB. Epigenetics, depression and antidepressant treatment. Current Pharmaceutical Design. 18: 5879-89. PMID 22681167  1
2012 Binder EB, Ressler KJ. Emerging methods in the molecular biology of neuropsychiatric disorders. Handbook of Clinical Neurology. 106: 191-209. PMID 22608622 DOI: 10.1016/B978-0-444-52002-9.00011-5  1
2012 Hunter JE, Leslie M, Novak G, Hamilton D, Shubeck L, Charen K, Abramowitz A, Epstein MP, Lori A, Binder E, Cubells JF, Sherman SL. Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 549-59. PMID 22573456 DOI: 10.1002/ajmg.b.32061  1
2012 Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, ... ... Binder EB, et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics. 44: 552-61. PMID 22504417 DOI: 10.1038/ng.2250  1
2012 Binder EB, Holsboer F. Low cortisol and risk and resilience to stress-related psychiatric disorders. Biological Psychiatry. 71: 282-3. PMID 22265026 DOI: 10.1016/j.biopsych.2011.12.008  1
2012 Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1455-64. PMID 22237309 DOI: 10.1038/npp.2011.331  1
2012 Menke A, Rex-Haffner M, Klengel T, Binder EB, Mehta D. Peripheral blood gene expression: it all boils down to the RNA collection tubes. Bmc Research Notes. 5: 1. PMID 22214347 DOI: 10.1186/1756-0500-5-1  1
2012 Mehta D, Quast C, Fasching PA, Seifert A, Voigt F, Beckmann MW, Faschingbauer F, Burger P, Ekici AB, Kornhuber J, Binder EB, Goecke TW. The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms. Journal of Affective Disorders. 136: 1192-7. PMID 22209125 DOI: 10.1016/j.jad.2011.11.042  1
2012 Cáceda R, Binder EB, Kinkead B, Nemeroff CB. The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion. Schizophrenia Research. 136: 88-95. PMID 22104138 DOI: 10.1016/j.schres.2011.10.013  1
2012 Heim C, Binder EB. Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Experimental Neurology. 233: 102-11. PMID 22101006 DOI: 10.1016/j.expneurol.2011.10.032  1
2012 Menke A, Domschke K, Czamara D, Klengel T, Hennings J, Lucae S, Baune BT, Arolt V, Müller-Myhsok B, Holsboer F, Binder EB. Genome-wide association study of antidepressant treatment-emergent suicidal ideation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 797-807. PMID 22030708 DOI: 10.1038/npp.2011.257  1
2012 Katz ER, Stowe ZN, Newport DJ, Kelley ME, Pace TW, Cubells JF, Binder EB. Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy. Psychological Medicine. 42: 943-56. PMID 21995950 DOI: 10.1017/S0033291711002121  1
2012 Menke A, Sämann P, Kloiber S, Czamara D, Lucae S, Hennings J, Heck A, Kohli MA, Czisch M, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes. Psychoneuroendocrinology. 37: 565-75. PMID 21962378 DOI: 10.1016/j.psyneuen.2011.09.003  1
2012 Mehta D, Binder EB. Gene × environment vulnerability factors for PTSD: the HPA-axis. Neuropharmacology. 62: 654-62. PMID 21439305 DOI: 10.1016/j.neuropharm.2011.03.009  1
2012 Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients (Neuropsychopharmacology (2012) 37, (1455-1464) DOI: 10.1038/npp.2011.331) Neuropsychopharmacology. 37: 1972. DOI: 10.1038/npp.2012.21  1
2011 Klengel T, Binder EB. Using gene-environment interactions to target personalized treatment in mood disorder. Personalized Medicine. 8: 23-34. PMID 29768787 DOI: 10.2217/pme.10.73  0.44
2011 Bradley B, Westen D, Mercer KB, Binder EB, Jovanovic T, Crain D, Wingo A, Heim C. Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: moderation by oxytocin receptor gene. Development and Psychopathology. 23: 439-52. PMID 23786688 DOI: 10.1017/S0954579411000162  1
2011 Zimmermann P, Brückl T, Nocon A, Pfister H, Binder EB, Uhr M, Lieb R, Moffitt TE, Caspi A, Holsboer F, Ising M. Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. The American Journal of Psychiatry. 168: 1107-16. PMID 21865530 DOI: 10.1176/appi.ajp.2011.10111577  1
2011 Schosser A, Butler AW, Ising M, Perroud N, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, ... ... Binder EB, et al. Genomewide association scan of suicidal thoughts and behaviour in major depression. Plos One. 6: e20690. PMID 21750702 DOI: 10.1371/journal.pone.0020690  1
2011 Altmann A, Weber P, Quast C, Rex-Haffner M, Binder EB, Müller-Myhsok B. vipR: variant identification in pooled DNA using R. Bioinformatics (Oxford, England). 27: i77-84. PMID 21685105 DOI: 10.1093/bioinformatics/btr205  1
2011 Horstmann S, Binder EB. Glucocorticoids as predictors of treatment response in depression. Harvard Review of Psychiatry. 19: 125-43. PMID 21631159 DOI: 10.3109/10673229.2011.586550  1
2011 Schosser A, Gaysina D, Cohen-Woods S, Domenici E, Perry J, Tozzi F, Korszun A, Gunasinghe C, Gray J, Jones L, Binder EB, Holsboer F, Craddock N, Owen MJ, Craig IW, et al. A follow-up case-control association study of tractable (druggable) genes in recurrent major depression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 640-50. PMID 21630437 DOI: 10.1002/ajmg.b.31204  1
2011 Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Archives of General Psychiatry. 68: 901-10. PMID 21536970 DOI: 10.1001/archgenpsychiatry.2011.50  1
2011 Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, ... ... Binder EB, et al. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 70: 252-65. PMID 21521612 DOI: 10.1016/j.neuron.2011.04.005  1
2011 Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, Norrholm SD, Kilaru V, Smith AK, Myers AJ, Ramirez M, Engel A, Hammack SE, Toufexis D, Braas KM, ... Binder EB, et al. Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature. 470: 492-7. PMID 21350482 DOI: 10.1038/nature09856  1
2011 Scharf SH, Liebl C, Binder EB, Schmidt MV, Müller MB. Expression and regulation of the Fkbp5 gene in the adult mouse brain. Plos One. 6: e16883. PMID 21347384 DOI: 10.1371/journal.pone.0016883  1
2011 Domschke K, Reif A, Weber H, Richter J, Hohoff C, Ohrmann P, Pedersen A, Bauer J, Suslow T, Kugel H, Heindel W, Baumann C, Klauke B, Jacob C, Maier W, ... ... Binder EB, et al. Neuropeptide S receptor gene -- converging evidence for a role in panic disorder. Molecular Psychiatry. 16: 938-48. PMID 20603625 DOI: 10.1038/mp.2010.81  1
2011 Dunlop BW, Betancourt Y, Binder EB, Heim C, Holsboer F, Ising M, McKenzie M, Mletzko T, Pfister H, Nemeroff CB, Craighead WE, Mayberg HS. Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder. Journal of Psychiatric Research. 45: 24-8. PMID 20488460 DOI: 10.1016/j.jpsychires.2010.04.020  1
2011 Erhardt A, Czibere L, Roeske D, Lucae S, Unschuld PG, Ripke S, Specht M, Kohli MA, Kloiber S, Ising M, Heck A, Pfister H, Zimmermann P, Lieb R, Pütz B, ... ... Binder EB, et al. TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies. Molecular Psychiatry. 16: 647-63. PMID 20368705 DOI: 10.1038/mp.2010.41  1
2011 Klengel T, Binder EB. Using gene-environment interactions to target personalized treatment in mood disorder Personalized Medicine. 8: 23-34. DOI: 10.2217/pme.10.73  1
2011 Gillespie CF, Binder EB, Holtzheimer PE, Nemeroff CB. Stress and the Impact of Personalized Medicine Integrative Neuroscience and Personalized Medicine. DOI: 10.1093/acprof:oso/9780195393804.003.0005  1
2011 Binder E, Mehta D, Ressler K, Holsboer F. Posttraumatic stress disorder subtypes invalid - Reply Archives of General Psychiatry. 68: 978-980. DOI: 10.1001/archgenpsychiatry.2011.94  1
2010 Schmidt MV, Trümbach D, Weber P, Wagner K, Scharf SH, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing JM, Wurst W, Binder EB, Holsboer F, et al. Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16949-58. PMID 21159965 DOI: 10.1523/JNEUROSCI.4668-10.2010  1
2010 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. Clinics in Laboratory Medicine. 30: 865-91. PMID 20832657 DOI: 10.1016/j.cll.2010.07.006  1
2010 Rietschel M, Mattheisen M, Frank J, Treutlein J, Degenhardt F, Breuer R, Steffens M, Mier D, Esslinger C, Walter H, Kirsch P, Erk S, Schnell K, Herms S, Wichmann HE, ... ... Binder EB, et al. Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression. Biological Psychiatry. 68: 578-85. PMID 20673876 DOI: 10.1016/j.biopsych.2010.05.038  1
2010 Mehta D, Menke A, Binder EB. Gene expression studies in major depression. Current Psychiatry Reports. 12: 135-44. PMID 20425299 DOI: 10.1007/s11920-010-0100-3  1
2010 Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB. Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Archives of General Psychiatry. 67: 369-79. PMID 20368512 DOI: 10.1001/archgenpsychiatry.2010.18  1
2010 Unschuld PG, Ising M, Roeske D, Erhardt A, Specht M, Kloiber S, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1583-92. PMID 20237460 DOI: 10.1038/npp.2010.30  1
2010 Kohli MA, Salyakina D, Pfennig A, Lucae S, Horstmann S, Menke A, Kloiber S, Hennings J, Bradley BB, Ressler KJ, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Archives of General Psychiatry. 67: 348-59. PMID 20124106 DOI: 10.1001/archgenpsychiatry.2009.201  1
2010 Binder EB, Newport DJ, Zach EB, Smith AK, Deveau TC, Altshuler LL, Cohen LS, Stowe ZN, Cubells JF. A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort. Journal of Psychiatric Research. 44: 640-6. PMID 20045118 DOI: 10.1016/j.jpsychires.2009.12.001  1
2010 Ressler KJ, Bradley B, Mercer KB, Deveau TC, Smith AK, Gillespie CF, Nemeroff CB, Cubells JF, Binder EB. Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 812-24. PMID 20029939 DOI: 10.1002/ajmg.b.31052  1
2010 Binder EB, Nemeroff CB. The CRF system, stress, depression and anxiety-insights from human genetic studies. Molecular Psychiatry. 15: 574-88. PMID 20010888 DOI: 10.1038/mp.2009.141  1
2010 Horstmann S, Lucae S, Menke A, Hennings JM, Ising M, Roeske D, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 727-40. PMID 19924111 DOI: 10.1038/npp.2009.180  1
2010 Kloiber S, Kohli MA, Brueckl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld PG, Horstmann S, Salyakina D, Muller-Myhsok B, Binder EB, Holsboer F, Lucae S. Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Molecular Psychiatry. 15: 736-47. PMID 19125159 DOI: 10.1038/mp.2008.142  1
2009 Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB, Ressler KJ, Binder EB. Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene. Frontiers in Behavioral Neuroscience. 3: 41. PMID 20161813 DOI: 10.3389/neuro.08.041.2009  1
2009 Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli MA, Hennings JM, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune BT, et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Archives of General Psychiatry. 66: 966-75. PMID 19736353 DOI: 10.1001/archgenpsychiatry.2009.95  1
2009 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. The Psychiatric Clinics of North America. 32: 549-75. PMID 19716990 DOI: 10.1016/j.psc.2009.05.004  1
2009 Horstmann S, Binder EB. Pharmacogenomics of antidepressant drugs. Pharmacology & Therapeutics. 124: 57-73. PMID 19563827 DOI: 10.1016/j.pharmthera.2009.06.007  1
2009 Binder EB. The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology. 34: S186-95. PMID 19560279 DOI: 10.1016/j.psyneuen.2009.05.021  1
2009 Unschuld PG, Ising M, Specht M, Erhardt A, Ripke S, Heck A, Kloiber S, Straub V, Brueckl T, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 1100-9. PMID 19229853 DOI: 10.1002/ajmg.b.30938  1
2009 Binder EB, Künzel HE, Nickel T, Kern N, Pfennig A, Majer M, Uhr M, Ising M, Holsboer F. HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients. Psychoneuroendocrinology. 34: 99-109. PMID 18829172 DOI: 10.1016/j.psyneuen.2008.08.018  1
2009 Thoeringer CK, Ripke S, Unschuld PG, Lucae S, Ising M, Bettecken T, Uhr M, Keck ME, Mueller-Myhsok B, Holsboer F, Binder EB, Erhardt A. The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 649-57. PMID 18607529 DOI: 10.1007/s00702-008-0075-y  1
2009 Hennings JM, Owashi T, Binder EB, Horstmann S, Menke A, Kloiber S, Dose T, Wollweber B, Spieler D, Messer T, Lutz R, Künzel H, Bierner T, Pollmächer T, Pfister H, et al. Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project. Journal of Psychiatric Research. 43: 215-29. PMID 18586274 DOI: 10.1016/j.jpsychires.2008.05.002  1
2009 Bull SJ, Huezo-Diaz P, Binder EB, Cubells JF, Ranjith G, Maddock C, Miyazaki C, Alexander N, Hotopf M, Cleare AJ, Norris S, Cassidy E, Aitchison KJ, Miller AH, Pariante CM. Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. Molecular Psychiatry. 14: 1095-104. PMID 18458677 DOI: 10.1038/mp.2008.48  1
2008 Menke A, Lucae S, Kloiber S, Horstmann S, Bettecken T, Uhr M, Ripke S, Ising M, Müller-Myhsok B, Holsboer F, Binder EB. Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation. The American Journal of Psychiatry. 165: 917-8. PMID 18593792 DOI: 10.1176/appi.ajp.2008.08020274  1
2008 Hodgkinson CA, Yuan Q, Xu K, Shen PH, Heinz E, Lobos EA, Binder EB, Cubells J, Ehlers CL, Gelernter J, Mann J, Riley B, Roy A, Tabakoff B, Todd RD, et al. Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol and Alcoholism (Oxford, Oxfordshire). 43: 505-15. PMID 18477577 DOI: 10.1093/alcalc/agn032  1
2008 Keck ME, Kern N, Erhardt A, Unschuld PG, Ising M, Salyakina D, Müller MB, Knorr CC, Lieb R, Hohoff C, Krakowitzky P, Maier W, Bandelow B, Fritze J, Deckert J, ... ... Binder EB, et al. Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1196-204. PMID 18384079 DOI: 10.1002/ajmg.b.30750  1
2008 Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, Schwartz AC, Cubells JF, Ressler KJ. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. Jama. 299: 1291-305. PMID 18349090 DOI: 10.1001/jama.299.11.1291  1
2008 Erhardt A, Lucae S, Kern N, Unschuld PG, Ising M, Lieb R, Uhr M, Hohoff C, Deckert J, Bandelow B, Maier W, Binder EB, Müller-Myhsok B, Keck ME, Holsboer F. Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks. Molecular Psychiatry. 13: 242-3. PMID 18285758 DOI: 10.1038/sj.mp.4002094  1
2008 Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, et al. Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Archives of General Psychiatry. 65: 190-200. PMID 18250257 DOI: 10.1001/archgenpsychiatry.2007.26  1
2008 Uhr M, Tontsch A, Namendorf C, Ripke S, Lucae S, Ising M, Dose T, Ebinger M, Rosenhagen M, Kohli M, Kloiber S, Salyakina D, Bettecken T, Specht M, Pütz B, ... Binder EB, et al. Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron. 57: 203-9. PMID 18215618 DOI: 10.1016/j.neuron.2007.11.017  1
2008 Unschuld PG, Ising M, Erhardt A, Lucae S, Kohli M, Kloiber S, Salyakina D, Thoeringer CK, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder. Journal of Affective Disorders. 105: 177-84. PMID 17573119 DOI: 10.1016/j.jad.2007.05.006  1
2008 Ressler KJ, Bradley RG, Cubells JF, Binder EB. Child abuse and adult major depression: No evidence of protective gene: Reply Archives of General Psychiatry. 65: 1337-1339. DOI: 10.1001/archpsyc.65.11.1337  1
2007 Himmerich H, Zimmermann P, Ising M, Kloiber S, Lucae S, Kunzel HE, Binder EB, Holsboer F, Uhr M. Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment. Neuropsychobiology. 55: 28-35. PMID 17556850 DOI: 10.1159/000103573  1
2007 Unschuld PG, Ising M, Erhardt A, Lucae S, Kloiber S, Kohli M, Salyakina D, Welt T, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 424-9. PMID 17440930 DOI: 10.1002/ajmg.b.30412  1
2007 Erhardt A, Lucae S, Unschuld PG, Ising M, Kern N, Salyakina D, Lieb R, Uhr M, Binder EB, Keck ME, Müller-Myhsok B, Holsboer F. Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders. Journal of Affective Disorders. 101: 159-68. PMID 17197037 DOI: 10.1016/j.jad.2006.11.016  1
2007 Ising M, Horstmann S, Kloiber S, Lucae S, Binder EB, Kern N, Künzel HE, Pfennig A, Uhr M, Holsboer F. Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker? Biological Psychiatry. 62: 47-54. PMID 17123470 DOI: 10.1016/j.biopsych.2006.07.039  1
2007 Thoeringer CK, Binder EB, Salyakina D, Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Brueckl TM, Mueller MB, Fuchs B, Puetz B, Lieb R, Uhr M, Holsboer F, et al. Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks. Journal of Psychiatric Research. 41: 579-84. PMID 16904689 DOI: 10.1016/j.jpsychires.2006.06.001  1
2006 Binder EB, Nemeroff CB. Implications for the practice of psychiatry. Progress in Brain Research. 158: 275-93. PMID 17027701 DOI: 10.1016/S0079-6123(06)58013-6  1
2006 Himmerich H, Binder EB, Künzel HE, Schuld A, Lucae S, Uhr M, Pollmächer T, Holsboer F, Ising M. Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis. Biological Psychiatry. 60: 882-8. PMID 16989778 DOI: 10.1016/j.biopsych.2006.03.075  1
2006 Baghai TC, Binder EB, Schule C, Salyakina D, Eser D, Lucae S, Zwanzger P, Haberger C, Zill P, Ising M, Deiml T, Uhr M, Illig T, Wichmann HE, Modell S, et al. Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. Molecular Psychiatry. 11: 1003-15. PMID 16924268 DOI: 10.1038/sj.mp.4001884  1
2006 Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Pütz B, Uhr M, Binder EB, Holsboer F, Keck ME. Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2515-22. PMID 16841071 DOI: 10.1038/sj.npp.1301168  1
2006 Lucae S, Salyakina D, Barden N, Harvey M, Gagné B, Labbé M, Binder EB, Uhr M, Paez-Pereda M, Sillaber I, Ising M, Brückl T, Lieb R, Holsboer F, Müller-Myhsok B. P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. Human Molecular Genetics. 15: 2438-45. PMID 16822851 DOI: 10.1093/hmg/ddl166  1
2006 Binder EB, Holsboer F. Pharmacogenomics and antidepressant drugs. Annals of Medicine. 38: 82-94. PMID 16581694 DOI: 10.1080/07853890600551045  1
2006 van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, Modell S, Salyakina D, Lamberts SW, Holsboer F. Polymorphisms of the glucocorticoid receptor gene and major depression. Biological Psychiatry. 59: 681-8. PMID 16580345 DOI: 10.1016/j.biopsych.2006.02.007  1
2006 Post A, Ackl N, Rücker M, Schreiber Y, Binder EB, Ising M, Sonntag A, Holsboer F, Almeida OF. Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression. Biological Psychiatry. 59: 858-62. PMID 16325150 DOI: 10.1016/j.biopsych.2005.09.007  1
2005 Binder EB, Holsboer F. Pharmacogenomics. Handbook of Experimental Pharmacology. 527-46. PMID 16594271 DOI: 10.1007/3-540-28082-0-19  1
2005 Brunner J, Bronisch T, Uhr M, Ising M, Binder E, Holsboer F, Turck CW. Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters. European Archives of Psychiatry and Clinical Neuroscience. 255: 438-40. PMID 16382377 DOI: 10.1007/s00406-005-0575-9  1
2005 Schumacher J, Jamra RA, Becker T, Ohlraun S, Klopp N, Binder EB, Schulze TG, Deschner M, Schmäl C, Höfels S, Zobel A, Illig T, Propping P, Holsboer F, Rietschel M, et al. Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression. Biological Psychiatry. 58: 307-14. PMID 16005437 DOI: 10.1016/j.biopsych.2005.04.006  1
2005 Ising M, Künzel HE, Binder EB, Nickel T, Modell S, Holsboer F. The combined dexamethasone/CRH test as a potential surrogate marker in depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 1085-93. PMID 15950349 DOI: 10.1016/j.pnpbp.2005.03.014  1
2005 Pfennig A, Kunzel HE, Kern N, Ising M, Majer M, Fuchs B, Ernst G, Holsboer F, Binder EB. Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression. Biological Psychiatry. 57: 336-42. PMID 15705348 DOI: 10.1016/j.biopsych.2004.11.017  1
2005 Post A, Ohl F, Almeida OF, Binder EB, Rücker M, Welt S, Binder E, Holsboer F, Sillaber I. Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919). Psychopharmacology. 180: 150-8. PMID 15682302 DOI: 10.1007/s00213-004-2134-x  1
2004 Majer M, Ising M, Künzel H, Binder EB, Holsboer F, Modell S, Zihl J. Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders. Psychological Medicine. 34: 1453-63. PMID 15724876 DOI: 10.1017/S0033291704002697  1
2004 Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, et al. Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nature Genetics. 36: 1319-25. PMID 15565110 DOI: 10.1038/ng1479  1
2004 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2200-7. PMID 15328528 DOI: 10.1038/sj.npp.1300546  1
2004 Keck ME, Müller MB, Binder EB, Sonntag A, Holsboer F. Ziprasidone-related tardive dyskinesia. The American Journal of Psychiatry. 161: 175-6. PMID 14702272 DOI: 10.1176/appi.ajp.161.1.175  1
2003 Künzel HE, Binder EB, Nickel T, Ising M, Fuchs B, Majer M, Pfennig A, Ernst G, Kern N, Schmid DA, Uhr M, Holsboer F, Modell S. Pharmacological and nonpharmacological factors influencing hypothalamic-pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2169-78. PMID 12931142 DOI: 10.1038/sj.npp.1300280  1
2003 Müller MB, Keck ME, Binder EB, Kresse AE, Hagemeyer TP, Landgraf R, Holsboer F, Uhr M. ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1991-9. PMID 12888779 DOI: 10.1038/sj.npp.1300257  0.44
2003 Ohl F, Roedel A, Binder E, Holsboer F. Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice. The European Journal of Neuroscience. 17: 128-36. PMID 12534976 DOI: 10.1046/j.1460-9568.2003.02436.x  0.44
2003 Müller MB, Keck ME, Binder EB, Kresse AE, Hagemeyer TP, Landgraf R, Holsboer F, Uhr M. ABCBI (MDRI)-Type P-Glycoproteins at the Blood-Brain Barrier Modulate the Activity of the Hypothalamic-Pituitary-Adrenocortical System: Implications for Affective Disorder Neuropsychopharmacology. 28: 1991-1999.  1
2002 Binder EB, Gross RE, Nemeroff CB, Kilts CD. Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. Psychopharmacology. 161: 288-95. PMID 12021832 DOI: 10.1007/s00213-002-1031-4  1
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs. Biological Psychiatry. 50: 856-72. PMID 11743941 DOI: 10.1016/S0006-3223(01)01211-2  1
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin and dopamine interactions. Pharmacological Reviews. 53: 453-86. PMID 11734615  1
2001 Mehr DR, Binder EF, Kruse RL, Zweig SC, Madsen RW, D'Agostino RB. Clinical findings associated with radiographic pneumonia in nursing home residents. The Journal of Family Practice. 50: 931-7. PMID 11711008  1
2001 Ohl F, Sillaber I, Binder E, Keck ME, Holsboer F. Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test. Journal of Psychiatric Research. 35: 147-54. PMID 11461710 DOI: 10.1016/S0022-3956(01)00017-6  0.44
2001 Binder EB, Kinkead B, Owens MJ, Kilts CD, Nemeroff CB. Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 601-8. PMID 11160439  1
1999 Kinkead B, Binder EB, Nemeroff CB. Does neurotensin mediate the effects of antipsychotic drugs? Biological Psychiatry. 46: 340-51. PMID 10435199 DOI: 10.1016/S0006-3223(99)00070-0  1
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