Hugh Hemmings - Publications

Affiliations: 
Cornell University, Ithaca, NY, United States 
Area:
Anesthesia

113 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Eastman RT, Rusinova R, Herold KF, Huang XP, Dranchak P, Voss TC, Rana S, Shrimp JH, White AD, Hemmings HC, Roth BL, Inglese J, Andersen OS, Dahlin JL. Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity. Biorxiv : the Preprint Server For Biology. PMID 37961094 DOI: 10.1101/2023.10.23.563088  0.488
2023 Speigel I, Patel K, Osman V, Hemmings HC. Volatile anesthetics inhibit presynaptic cGMP signaling to depress presynaptic excitability in rat hippocampal neurons. Neuropharmacology. 240: 109705. PMID 37683886 DOI: 10.1016/j.neuropharm.2023.109705  0.81
2023 Osman V, Speigel I, Patel K, Hemmings HC. Isoflurane alters presynaptic endoplasmic reticulum calcium dynamics in wild-type and malignant hyperthermia-susceptible rodent hippocampal neurons. Eneuro. PMID 37591734 DOI: 10.1523/ENEURO.0114-23.2023  0.798
2022 Williams RA, Johnson KW, Lee FS, Hemmings HC, Platholi J. A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures. Frontiers in Molecular Neuroscience. 15: 927149. PMID 35813074 DOI: 10.3389/fnmol.2022.927149  0.762
2022 Speigel IA, Patel K, Hemmings HC. Distinct effects of volatile and intravenous anaesthetics on presynaptic calcium dynamics in mouse hippocampal GABAergic neurones. British Journal of Anaesthesia. PMID 35164969 DOI: 10.1016/j.bja.2022.01.014  0.798
2022 Speigel IA, Hemmings HC. Relevance of Cortical and Hippocampal Interneuron Functional Diversity to General Anesthetic Mechanisms: A Narrative Review. Frontiers in Synaptic Neuroscience. 13: 812905. PMID 35153712 DOI: 10.3389/fnsyn.2021.812905  0.803
2021 Speigel IA, Hemmings HC. Selective inhibition of gamma aminobutyric acid release from mouse hippocampal interneurone subtypes by the volatile anaesthetic isoflurane. British Journal of Anaesthesia. PMID 34384592 DOI: 10.1016/j.bja.2021.06.042  0.789
2021 Platholi J, Hemmings HC. Effects of general anesthetics on synaptic transmission and plasticity. Current Neuropharmacology. PMID 34344292 DOI: 10.2174/1570159X19666210803105232  0.764
2021 Platholi J, Hemmings HC. Modulation of dendritic spines by protein phosphatase-1. Advances in Pharmacology (San Diego, Calif.). 90: 117-144. PMID 33706930 DOI: 10.1016/bs.apha.2020.10.001  0.772
2019 Koyanagi Y, Torturo CL, Cook DC, Zhou Z, Hemmings HC. Role of specific presynaptic calcium channel subtypes in isoflurane inhibition of synaptic vesicle exocytosis in rat hippocampal neurones. British Journal of Anaesthesia. PMID 31056238 DOI: 10.1016/J.Bja.2019.03.029  0.68
2019 Zhou C, Johnson KW, Herold KF, Hemmings HC. Differential Inhibition of Neuronal Sodium Channel Subtypes by the General Anesthetic Isoflurane. The Journal of Pharmacology and Experimental Therapeutics. PMID 30792243 DOI: 10.1124/jpet.118.254938  0.542
2019 Torturo CL, Zhou ZY, Ryan TA, Hemmings HC. Isoflurane Inhibits Dopaminergic Synaptic Vesicle Exocytosis Coupled to Ca2.1 and Ca2.2 in Rat Midbrain Neurons. Eneuro. 6. PMID 30680310 DOI: 10.1523/ENEURO.0278-18.2018  0.675
2019 Hemmings H, Koyanagi Y, Torturo C, Cook D, Zhou Z. Roles of presynaptic P/Q- and N-type calcium channels in inhibition of synaptic vesicle exocytosis by isoflurane in rat hippocampal neurones British Journal of Anaesthesia. 122: e51-e52. DOI: 10.1016/J.Bja.2018.10.048  0.666
2017 Johnson KW, Herold KF, Milner TA, Hemmings HC, Platholi J. Sodium channel subtypes are differentially localized to pre- and post-synaptic sites in rat hippocampus. The Journal of Comparative Neurology. PMID 28758202 DOI: 10.1002/Cne.24291  0.785
2017 Herold KF, Andersen OS, Hemmings HC. Divergent effects of anesthetics on lipid bilayer properties and sodium channel function. European Biophysics Journal : Ebj. PMID 28695248 DOI: 10.1007/S00249-017-1239-1  0.524
2017 Sand RM, Gingrich KJ, Macharadze T, Herold KF, Hemmings HC. Isoflurane modulates activation and inactivation gating of the prokaryotic Na(+) channel NaChBac. The Journal of General Physiology. PMID 28416648 DOI: 10.1085/Jgp.201611600  0.511
2017 Herold KF, Sanford RL, Lee W, Andersen OS, Hemmings HC. Clinical concentrations of chemically diverse general anesthetics minimally affect lipid bilayer properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265069 DOI: 10.1073/Pnas.1611717114  0.495
2017 Herold K, Lee W, Sanford R, Andersen OS, Hemmings HC. General Anesthetics Minimally affect Lipid Bilayer Properties at Clinical Concentrations Biophysical Journal. 112: 227a. DOI: 10.1016/J.Bpj.2016.11.1249  0.492
2016 Hara M, Zhou ZY, Hemmings HC. α2-Adrenergic Receptor and Isoflurane Modulation of Presynaptic Ca2+ Influx and Exocytosis in Hippocampal Neurons. Anesthesiology. PMID 27337223 DOI: 10.1097/Aln.0000000000001213  0.672
2015 Baumgart JP, Zhou ZY, Hara M, Cook DC, Hoppa MB, Ryan TA, Hemmings HC. Isoflurane inhibits synaptic vesicle exocytosis through reduced Ca2+ influx, not Ca2+-exocytosis coupling. Proceedings of the National Academy of Sciences of the United States of America. PMID 26351670 DOI: 10.1073/Pnas.1500525112  0.785
2015 Purtell K, Gingrich KJ, Ouyang W, Herold KF, Hemmings HC. Activity-dependent depression of neuronal sodium channels by the general anaesthetic isoflurane. British Journal of Anaesthesia. 115: 112-21. PMID 26089447 DOI: 10.1093/Bja/Aev203  0.564
2014 Herold KF, Sanford RL, Lee W, Schultz MF, Ingólfsson HI, Andersen OS, Hemmings HC. Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties. The Journal of General Physiology. 144: 545-60. PMID 25385786 DOI: 10.1085/Jgp.201411172  0.521
2014 Platholi J, Herold KF, Hemmings HC, Halpain S. Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism. Plos One. 9: e102978. PMID 25068870 DOI: 10.1371/Journal.Pone.0102978  0.779
2014 Platholi J, Federman A, Detert JA, Heerdt P, Hemmings HC. Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase. The Journal of Biological Chemistry. 289: 23893-900. PMID 25028520 DOI: 10.1074/Jbc.M114.557744  0.768
2014 Ingólfsson HI, Thakur P, Herold KF, Hobart EA, Ramsey NB, Periole X, de Jong DH, Zwama M, Yilmaz D, Hall K, Maretzky T, Hemmings HC, Blobel C, Marrink SJ, Koçer A, et al. Phytochemicals perturb membranes and promiscuously alter protein function. Acs Chemical Biology. 9: 1788-98. PMID 24901212 DOI: 10.1021/Cb500086E  0.51
2014 Sand R, Macharadze T, Hemmings H. Modulation of Inactivation Kinetics of the Bacterial Sodium Channel Nachbac Suggests a Complex Mode of Inhibition by Isoflurane Biophysical Journal. 106: 132a. DOI: 10.1016/J.BPJ.2013.11.776  0.314
2014 Herold KF, Lee W, Sanford RL, Andersen OS, Hemmings HC. General Anesthetics do not Alter Lipid Bilayer Properties at Clinically Relevant Concentrations Biophysical Journal. 106: 515a. DOI: 10.1016/J.Bpj.2013.11.2877  0.498
2014 Purtell K, Herold KF, Ouyang W, Gingrich KJ, Hemmings HC. Frequency-Dependent Inhibition of Sodium Channels by the General Anesthetic Isoflurane Biophysical Journal. 106: 325a. DOI: 10.1016/J.Bpj.2013.11.1870  0.547
2013 Jevtovic-Todorovic V, Absalom AR, Blomgren K, Brambrink A, Crosby G, Culley DJ, Fiskum G, Giffard RG, Herold KF, Loepke AW, Ma D, Orser BA, Planel E, Slikker W, Soriano SG, ... ... Hemmings HC, et al. Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. British Journal of Anaesthesia. 111: 143-51. PMID 23722106 DOI: 10.1093/Bja/Aet177  0.499
2013 Tibbs GR, Rowley TJ, Sanford RL, Herold KF, Proekt A, Hemmings HC, Andersen OS, Goldstein PA, Flood PD. HCN1 channels as targets for anesthetic and nonanesthetic propofol analogs in the amelioration of mechanical and thermal hyperalgesia in a mouse model of neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 345: 363-73. PMID 23549867 DOI: 10.1124/Jpet.113.203620  0.512
2013 Ingólfsson HI, Thakur P, Herold KF, Maretzky T, Hall K, Zwama M, Yilmaz D, Hemmings HC, Blobel C, Koçer A, Sack J, Andersen OS. Phytochemicals Promiscuously Alter Membrane Protein Function and Bilayer Properties Biophysical Journal. 104: 93a. DOI: 10.1016/J.Bpj.2012.11.557  0.507
2013 Baumgart JP, Zhou Z, Hoppa MB, Lasiecka ZM, Hemmings HC. Effects of Isoflurane on Intracellular Calcium in Boutons of Hippocampal Neurons Biophysical Journal. 104: 499a. DOI: 10.1016/J.Bpj.2012.11.2755  0.784
2013 Herold KF, Lee W, Sanford RL, Eger EI, Andersen OS, Hemmings HC. Combined Stopped-Flow and Electrophysiological Experiments Suggest Direct Sodium Channel Inhibition by Model Fluorobenzene Anesthetics Biophysical Journal. 104: 427a-428a. DOI: 10.1016/J.Bpj.2012.11.2379  0.513
2013 Hudson AE, Herold KF, Hemmings HC. Pharmacology of Inhaled Anesthetics Pharmacology and Physiology For Anesthesia: Foundations and Clinical Application. 159-179. DOI: 10.1016/B978-1-4377-1679-5.00010-7  0.472
2012 Herold KF, Hemmings HC. Sodium channels as targets for volatile anesthetics. Frontiers in Pharmacology. 3: 50. PMID 22479247 DOI: 10.3389/fphar.2012.00050  0.55
2011 Walaas SI, Hemmings HC, Greengard P, Nairn AC. Beyond the dopamine receptor: regulation and roles of serine/threonine protein phosphatases. Frontiers in Neuroanatomy. 5: 50. PMID 21904525 DOI: 10.3389/fnana.2011.00050  0.73
2011 Rusinova R, Herold KF, Sanford RL, Greathouse DV, Hemmings HC, Andersen OS. Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery. The Journal of General Physiology. 138: 249-70. PMID 21788612 DOI: 10.1085/Jgp.201010529  0.516
2011 Hemmings HC, Mackie K. The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation. Anesthesiology. 114: 1277-9. PMID 21532461 DOI: 10.1097/ALN.0b013e31821c647d  0.348
2010 Bendor J, Lizardi-Ortiz JE, Westphalen RI, Brandstetter M, Hemmings HC, Sulzer D, Flajolet M, Greengard P. AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release. The Embo Journal. 29: 2813-26. PMID 20664521 DOI: 10.1038/emboj.2010.154  0.403
2010 Hemmings HC, Greengard P. Positively active: how local anesthetics work. Anesthesiology. 113: 250-2. PMID 20526177 DOI: 10.1097/ALN.0b013e3181e32e84  0.307
2010 Westphalen RI, Yu J, Krivitski M, Jih TY, Hemmings HC. Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat CNS. Journal of Neurochemistry. 113: 1611-20. PMID 20374421 DOI: 10.1111/j.1471-4159.2010.06722.x  0.578
2010 Glausier JR, Maddox M, Hemmings HC, Nairn AC, Greengard P, Muly EC. Localization of dopamine- and cAMP-regulated phosphoprotein-32 and inhibitor-1 in area 9 of Macaca mulatta prefrontal cortex. Neuroscience. 167: 428-38. PMID 20156529 DOI: 10.1016/j.neuroscience.2010.02.014  0.629
2010 Rusinova R, Herold KF, Koeppe RE, Hemmings H, Andersen OS. Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function Biophysical Journal. 98: 480a. DOI: 10.1016/J.Bpj.2009.12.2612  0.511
2009 Herold KF, Nau C, Ouyang W, Hemmings HC. Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8. Anesthesiology. 111: 591-9. PMID 19672182 DOI: 10.1097/ALN.0b013e3181af64d4  0.541
2009 Ouyang W, Herold KF, Hemmings HC. Comparative effects of halogenated inhaled anesthetics on voltage-gated Na+ channel function. Anesthesiology. 110: 582-90. PMID 19225394 DOI: 10.1097/ALN.0b013e318197941e  0.515
2008 Platholi J, Heerdt PM, Lim Tung HY, Hemmings HC. Activation of brain protein phosphatase-1(I) following cardiac arrest and resuscitation involving an interaction with 14-3-3 gamma. Journal of Neurochemistry. 105: 2029-38. PMID 18284617 DOI: 10.1111/J.1471-4159.2008.05300.X  0.764
2008 Zhang TT, Platholi J, Heerdt PM, Hemmings HC, Tung HY. Protein phosphatase-2A is activated in pig brain following cardiac arrest and resuscitation. Metabolic Brain Disease. 23: 95-104. PMID 18197471 DOI: 10.1007/S11011-007-9074-1  0.73
2007 Snyder GL, Galdi S, Hendrick JP, Hemmings HC. General anesthetics selectively modulate glutamatergic and dopaminergic signaling via site-specific phosphorylation in vivo. Neuropharmacology. 53: 619-30. PMID 17826804 DOI: 10.1016/j.neuropharm.2007.07.008  0.339
2007 Bullock SA, Platholi J, Gjyrezi A, Heerdt PM, Tung HY, Hemmings HC. Differential regulation of protein phosphatase-1(I) by neurabin. Biochemical and Biophysical Research Communications. 358: 140-4. PMID 17467665 DOI: 10.1016/J.Bbrc.2007.04.076  0.764
2007 Nguyen C, Nishi A, Kansy JW, Fernandez J, Hayashi K, Gillardon F, Hemmings HC, Nairn AC, Bibb JA. Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5. The Journal of Biological Chemistry. 282: 16511-20. PMID 17400554 DOI: 10.1074/jbc.M701046200  0.689
2007 Hotte M, Thuault S, Dineley KT, Hemmings HC, Nairn AC, Jay TM. Phosphorylation of CREB and DARPP-32 during late LTP at hippocampal to prefrontal cortex synapses in vivo. Synapse (New York, N.Y.). 61: 24-8. PMID 17068779 DOI: 10.1002/syn.20339  0.475
2007 Platholi J, Heerdt P, Tung HL, Hemmings H. Protein phosphatase‐1I activation in brain following cardiac arrest and resuscitation The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A618-D  0.75
2006 Hotte M, Thuault S, Lachaise F, Dineley KT, Hemmings HC, Nairn AC, Jay TM. D1 receptor modulation of memory retrieval performance is associated with changes in pCREB and pDARPP-32 in rat prefrontal cortex. Behavioural Brain Research. 171: 127-33. PMID 16687181 DOI: 10.1016/j.bbr.2006.03.026  0.425
2006 Hemmings HC, Girault JA. Cell Signaling Foundations of Anesthesia. 31-50. DOI: 10.1016/B978-0-323-03707-5.50009-7  0.385
2005 Futter M, Uematsu K, Bullock SA, Kim Y, Hemmings HC, Nishi A, Greengard P, Nairn AC. Phosphorylation of spinophilin by ERK and cyclin-dependent PK 5 (Cdk5). Proceedings of the National Academy of Sciences of the United States of America. 102: 3489-94. PMID 15728359 DOI: 10.1073/pnas.0409802102  0.595
2005 Hemmings HC, Yan W, Westphalen RI, Ryan TA. The general anesthetic isoflurane depresses synaptic vesicle exocytosis. Molecular Pharmacology. 67: 1591-9. PMID 15728262 DOI: 10.1124/mol.104.003210  0.303
2002 Albert KA, Hemmings HC, Adamo AI, Potkin SG, Akbarian S, Sandman CA, Cotman CW, Bunney WE, Greengard P. Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia. Archives of General Psychiatry. 59: 705-12. PMID 12150646 DOI: 10.1001/Archpsyc.59.8.705  0.41
2001 Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ. Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7944-53. PMID 11588168  0.714
2001 Lingamaneni R, Krasowski MD, Jenkins A, Truong T, Giunta AL, Blackbeer J, MacIver MB, Harrison NL, Hemmings HC. Anesthetic properties of 4-iodopropofol: implications for mechanisms of anesthesia. Anesthesiology. 94: 1050-7. PMID 11465597 DOI: 10.1097/00000542-200106000-00020  0.671
2001 Jovanovic JN, Sihra TS, Nairn AC, Hemmings HC, Greengard P, Czernik AJ. Opposing Changes in Phosphorylation of Specific Sites in Synapsin I During Ca2+-Dependent Glutamate Release in Isolated Nerve Terminals The Journal of Neuroscience. 21: 7944-7953. DOI: 10.1523/Jneurosci.21-20-07944.2001  0.801
2000 Blanck TJ, Haile M, Xu F, Zhang J, Heerdt P, Veselis RA, Beckman J, Kang R, Adamo A, Hemmings H. Isoflurane pretreatment ameliorates postischemic neurologic dysfunction and preserves hippocampal Ca2+/calmodulin-dependent protein kinase in a canine cardiac arrest model. Anesthesiology. 93: 1285-93. PMID 11046218 DOI: 10.1097/00000542-200011000-00023  0.306
2000 Caporaso GL, Bibb JA, Snyder GL, Valle C, Rakhilin S, Fienberg AA, Hemmings HC, Nairn AC, Greengard P. Drugs of abuse modulate the phosphorylation of ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in the basal ganglia. Neuropharmacology. 39: 1637-44. PMID 10854908 DOI: 10.1016/S0028-3908(99)00230-0  0.742
1999 Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC, Nairn AC, Greengard P. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature. 402: 669-71. PMID 10604473 DOI: 10.1038/45251  0.812
1999 McAvoy T, Allen PB, Obaishi H, Nakanishi H, Takai Y, Greengard P, Nairn AC, Hemmings HC. Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation. Biochemistry. 38: 12943-9. PMID 10504266 DOI: 10.1021/Bi991227D  0.578
1999 Mayerhofer A, Hemmings HC, Snyder GL, Greengard P, Boddien S, Berg U, Brucker C. Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro. The Journal of Clinical Endocrinology and Metabolism. 84: 257-64. PMID 9920093 DOI: 10.1210/Jcem.84.1.5378  0.39
1998 McAvov T, Nairn AC, Greengard P, Hemmings HC. Identification and purification of protein phosphatase 1 binding proteins in rat brain Faseb Journal. 12: A1300.  0.434
1997 Schnabel R, Metzger M, Jiang S, Hemmings HC, Greengard P, Braun K. Localization of dopamine D1 receptors and dopaminoceptive neurons in the chick forebrain. The Journal of Comparative Neurology. 388: 146-68. PMID 9364244 DOI: 10.1002/(SICI)1096-9861(19971110)388:1<146::AID-CNE10>3.0.CO;2-T  0.402
1996 Hemmings HC, Adamo AI. Activation of endogenous protein kinase C by halothane in synaptosomes. Anesthesiology. 84: 652-62. PMID 8659794 DOI: 10.1097/00000542-199603000-00021  0.327
1996 Chang S, Hemmings HC, Aderem A. Stimulus-dependent phosphorylation of MacMARCKS, a protein kinase C substrate, in nerve termini and PC12 cells. The Journal of Biological Chemistry. 271: 1174-8. PMID 8557647 DOI: 10.1074/jbc.271.2.1174  0.327
1995 Surmeier DJ, Bargas J, Hemmings HC, Nairn AC, Greengard P. Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons. Neuron. 14: 385-97. PMID 7531987 DOI: 10.1016/0896-6273(95)90294-5  0.626
1994 Hvalby O, Hemmings HC, Paulsen O, Czernik AJ, Nairn AC, Godfraind JM, Jensen V, Raastad M, Storm JF, Andersen P. Specificity of protein kinase inhibitor peptides and induction of long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America. 91: 4761-5. PMID 8197132 DOI: 10.1073/Pnas.91.11.4761  0.48
1994 Fisone G, Cheng SX, Nairn AC, Czernik AJ, Hemmings HC, Höög JO, Bertorello AM, Kaiser R, Bergman T, Jörnvall H. Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis. The Journal of Biological Chemistry. 269: 9368-73. PMID 7510709  0.441
1992 Hemmings HC, Girault JA, Nairn AC, Bertuzzi G, Greengard P. Distribution of protein phosphatase inhibitor-1 in brain and peripheral tissues of various species: comparison with DARPP-32. Journal of Neurochemistry. 59: 1053-61. PMID 1353788 DOI: 10.1111/j.1471-4159.1992.tb08347.x  0.631
1991 Gustafson EL, Girault JA, Hemmings HC, Nairn AC, Greengard P. Immunocytochemical localization of phosphatase inhibitor-1 in rat brain. The Journal of Comparative Neurology. 310: 170-88. PMID 1955581 DOI: 10.1002/cne.903100204  0.698
1991 Aperia A, Fryckstedt J, Svensson L, Hemmings HC, Nairn AC, Greengard P. Phosphorylated Mr 32,000 dopamine- and cAMP-regulated phosphoprotein inhibits Na+,K(+)-ATPase activity in renal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 2798-801. PMID 1849276 DOI: 10.1073/pnas.88.7.2798  0.573
1991 Meister B, Arvidsson U, Hemmings HC, Greengard P, Hökfelt T. Dopamine- and adenosine-3':5'-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human. Neuroscience Letters. 131: 66-70. PMID 1791981 DOI: 10.1016/0304-3940(91)90338-T  0.355
1991 Meister B, Schultzberg M, Hemmings HC, Greengard P, Goldstein M, Hökfelt T. Dopamine- and adenosine-3',5'-monophosphate (cAMP)-regulated phosphoprotein of 32 kDa (DARPP-32) in the adrenal gland: immunohistochemical localization. Journal of the Autonomic Nervous System. 36: 75-84. PMID 1721636 DOI: 10.1016/0165-1838(91)90132-M  0.434
1991 Meister B, Askergren J, Tunevall G, Hemmings HC, Greengard P. Identification of a dopamine- and 3'5'-cyclic adenosine monophosphate-regulated phosphoprotein of 32 kD (DARPP-32) in parathyroid hormone-producing cells of the human parathyroid gland. Journal of Endocrinological Investigation. 14: 655-61. PMID 1663529 DOI: 10.1007/BF03347888  0.419
1991 Meister B, Arvidsson U, Hemmings HC, Greengard P, Hökfelt T. Dopamine- and adenosine-3′:5′-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human Neuroscience Letters. 131: 66-70. DOI: 10.1016/0304-3940(91)90338-T  0.385
1990 Hemmings HC, Nairn AC, Elliott JI, Greengard P. Synthetic peptide analogs of DARPP-32 (Mr 32,000 dopamine- and cAMP-regulated phosphoprotein), an inhibitor of protein phosphatase-1. Phosphorylation, dephosphorylation, and inhibitory activity. The Journal of Biological Chemistry. 265: 20369-76. PMID 2173704  0.504
1990 Girault JA, Hemmings HC, Zorn SH, Gustafson EL, Greengard P. Characterization in mammalian brain of a DARPP-32 serine kinase identical to casein kinase II. Journal of Neurochemistry. 55: 1772-83. PMID 2145398 DOI: 10.1111/j.1471-4159.1990.tb04968.x  0.622
1990 Girault JA, Walaas SI, Hemmings HC, Greengard P. ARPP-21, a cAMP-regulated phosphoprotein enriched in dopamine-innervated brain regions: tissue distribution and regulation of phosphorylation in rat brain. Neuroscience. 37: 317-25. PMID 1966823 DOI: 10.1016/0306-4522(90)90402-P  0.759
1989 Meister B, Fryckstedt J, Schalling M, Cortés R, Hökfelt T, Aperia A, Hemmings HC, Nairn AC, Ehrlich M, Greengard P. Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 8068-72. PMID 2573060 DOI: 10.1073/PNAS.86.20.8068  0.58
1989 Girault JA, Hemmings HC, Williams KR, Nairn AC, Greengard P. Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase II. The Journal of Biological Chemistry. 264: 21748-59. PMID 2557337  0.626
1989 Williams KR, Hemmings HC, LoPresti MB, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3631-7. PMID 2552036 DOI: 10.1523/Jneurosci.09-10-03631.1989  0.372
1989 Hemmings HC, Girault JA, Williams KR, LoPresti MB, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein (Mr = 21,000) enriched in dopamine-innervated brain regions. Amino acid sequence of the site phosphorylated by cyclic AMP in intact cells and kinetic studies of its phosphorylation in vitro. The Journal of Biological Chemistry. 264: 7726-33. PMID 2540203  0.532
1989 Strålfors P, Hemmings HC, Greengard P. Inhibitors of protein phosphatase-1. Inhibitor-1 of bovine adipose tissue and a dopamine- and cAMP-regulated phosphoprotein of bovine brain are identical. European Journal of Biochemistry / Febs. 180: 143-8. PMID 2540000 DOI: 10.1111/J.1432-1033.1989.TB14624.X  0.44
1989 Ouimet CC, Hemmings HC, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Immunocytochemical localization in rat brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 865-75. PMID 2538585  0.652
1989 Hemmings HC, Nairn AC, McGuinness TL, Huganir RL, Greengard P. Role of protein phosphorylation in neuronal signal transduction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 3: 1583-92. PMID 2493406 DOI: 10.1096/fasebj.3.5.2493406  0.708
1989 Williams K, Hemmings H, LoPresti M, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine- innervated brain regions. I. Amino acid sequence of ARPP-21B from bovine caudate nucleus The Journal of Neuroscience. 9: 3631-3637. DOI: 10.1523/JNEUROSCI.09-10-03631.1989  0.403
1989 Ouimet C, Hemmings H, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine- innervated brain regions. II. Immunocytochemical localization in rat brain The Journal of Neuroscience. 9: 865-875. DOI: 10.1523/Jneurosci.09-03-00865.1989  0.716
1989 Hemmings H, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine- innervated brain regions. I. Purification and characterization of the protein from bovine caudate nucleus The Journal of Neuroscience. 9: 851-864. DOI: 10.1523/JNEUROSCI.09-03-00851.1989  0.463
1988 Nairn AC, Hemmings HC, Walaas SI, Greengard P. DARPP-32 and phosphatase inhibitor-1, two structurally related inhibitors of protein phosphatase-1, are both present in striatonigral neurons. Journal of Neurochemistry. 50: 257-62. PMID 3335843 DOI: 10.1111/j.1471-4159.1988.tb13258.x  0.738
1988 Ouimet CC, Hemmings HC, Greengard P. Dopamine-regulated protein phosphorylation in the basal ganglia. Advances in Experimental Medicine and Biology. 235: 1-17. PMID 3067550 DOI: 10.1007/978-1-4899-2723-1_1  0.716
1988 Hökfelt T, Foster G, Schultzberg M, Meister B, Schalling M, Goldstein M, Hemmings HC, Ouimet C, Greengard P. DARPP-32 as a marker for D-1 dopaminoceptive cells in the rat brain: prenatal development and presence in glial elements (tanycytes) in the basal hypothalamus. Advances in Experimental Medicine and Biology. 235: 65-82. PMID 2976255 DOI: 10.1007/978-1-4899-2723-1_6  0.697
1988 Agnati LF, Fuxe K, Zoli M, Ferraguti F, Benfenati F, Ouimet CC, Walaas SI, Hemmings HC, Goldstein M, Greengard P. Morphometrical evidence for a complex organization of tyrosine hydroxylase-, enkephalin- and DARPP-32-like immunoreactive patches and their codistribution at three rostrocaudal levels in the rat neostriatum. Neuroscience. 27: 785-97. PMID 2908056 DOI: 10.1016/0306-4522(88)90183-2  0.797
1988 Meister B, Hökfelt T, Tsuruo Y, Hemmings H, Ouimet C, Greengard P, Goldstein M. DARPP-32, a dopamine- and cyclic AMP-regulated phosphoprotein in tanycytes of the mediobasal hypothalamus: distribution and relation to dopamine and luteinizing hormone-releasing hormone neurons and other glial elements. Neuroscience. 27: 607-22. PMID 2905789 DOI: 10.1016/0306-4522(88)90292-8  0.708
1988 Foster GA, Schultzberg M, Kökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P. Ontogeny of the dopamine and cyclic adenosine-3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the pre- and postnatal mouse central nervous system. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 6: 367-86. PMID 2903614 DOI: 10.1016/0736-5748(88)90020-2  0.769
1988 Meister B, Fried G, Hökfelt T, Hemmings HC, Greengard P. Immunohistochemical evidence for the existence of a dopamine- and cyclic AMP-regulated phosphoprotein (DARPP-32) in brown adipose tissue of pigs. Proceedings of the National Academy of Sciences of the United States of America. 85: 8713-6. PMID 2847173 DOI: 10.1073/PNAS.85.22.8713  0.395
1987 Foster GA, Schultzberg M, Hökfelt T, Goldstein M, Hemmings HC, Ouimet CC, Walaas SI, Greengard P. Development of a dopamine- and cyclic adenosine 3':5'-monophosphate-regulated phosphoprotein (DARPP-32) in the prenatal rat central nervous system, and its relationship to the arrival of presumptive dopaminergic innervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 7: 1994-2018. PMID 2886563 DOI: 10.1523/Jneurosci.07-07-01994.1987  0.763
1987 Hemmings HC, Walaas SI, Ouimet CC, Greengard P. Dopaminergic regulation of protein phosphorylation in the striatum: DARPP-32 Trends in Neurosciences. 10: 377-383. DOI: 10.1016/0166-2236(87)90075-0  0.799
1986 Hemmings HC, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1469-81. PMID 3711991 DOI: 10.1523/Jneurosci.06-05-01469.1986  0.359
1986 Hemmings HC, Greengard P. DARPP-32, a dopamine-regulated phosphoprotein. Progress in Brain Research. 69: 149-59. PMID 3328873 DOI: 10.1016/S0079-6123(08)61056-0  0.483
1986 Hemmings HC, Nairn AC, Greengard P. Protein kinases and phosphoproteins in the nervous system. Research Publications - Association For Research in Nervous and Mental Disease. 64: 47-69. PMID 3014627  0.467
1986 Stone RA, Laties AM, Hemmings HC, Ouimet CC, Greengard P. DARPP-32 in the ciliary epithelium of the eye: a neurotransmitter-regulated phosphoprotein of brain localizes to secretory cells. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 34: 1465-8. PMID 2877023 DOI: 10.1177/34.11.2877023  0.685
1986 Hemmings H, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution The Journal of Neuroscience. 6: 1469-1481. DOI: 10.1523/JNEUROSCI.06-05-01469.1986  0.381
1985 Nairn AC, Hemmings HC, Greengard P. Protein kinases in the brain. Annual Review of Biochemistry. 54: 931-76. PMID 2411213 DOI: 10.1146/annurev.bi.54.070185.004435  0.569
1984 Hemmings HC, Nairn AC, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase inhibitor 1. The Journal of Biological Chemistry. 259: 14491-7. PMID 6501303  0.519
1984 Hemmings HC, Nairn AC, Aswad DW, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 99-110. PMID 6319628 DOI: 10.1523/Jneurosci.04-01-00099.1984  0.723
1984 Ouimet CC, Miller PE, Hemmings HC, Walaas SI, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 4: 111-24. PMID 6319625 DOI: 10.1523/Jneurosci.04-01-00111.1984  0.779
1984 Hemmings HC, Greengard P, Tung HY, Cohen P. DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1. Nature. 310: 503-5. PMID 6087160 DOI: 10.1038/310503A0  0.52
1984 Ouimet C, Miller P, Hemmings H, Walaas S, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization The Journal of Neuroscience. 4: 111-124. DOI: 10.1523/JNEUROSCI.04-01-00111.1984  0.757
1984 Hemmings H, Nairn A, Aswad D, Greengard P. DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the phosphoprotein from bovine caudate nucleus The Journal of Neuroscience. 4: 99-110. DOI: 10.1523/JNEUROSCI.04-01-00099.1984  0.718
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