| Year |
Citation |
Score |
| 2015 |
Wang X, Blanchard J, Grundke-Iqbal I, Iqbal K. Memantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive Impairment. Plos One. 10: e0145441. PMID 26697860 DOI: 10.1371/Journal.Pone.0145441 |
0.606 |
|
| 2015 |
Kazim SF, Cardenas-Aguayo Mdel C, Arif M, Blanchard J, Fayyaz F, Grundke-Iqbal I, Iqbal K. Sera from children with autism induce autistic features which can be rescued with a CNTF small peptide mimetic in rats. Plos One. 10: e0118627. PMID 25769033 DOI: 10.1371/Journal.Pone.0118627 |
0.457 |
|
| 2015 |
Wang X, Blanchard J, Tung YC, Grundke-Iqbal I, Iqbal K. Inhibition of Protein Phosphatase-2A (PP2A) by I1PP2A Leads to Hyperphosphorylation of Tau, Neurodegeneration, and Cognitive Impairment in Rats. Journal of Alzheimer's Disease : Jad. 45: 423-35. PMID 25589718 DOI: 10.3233/Jad-142403 |
0.618 |
|
| 2015 |
Dai CL, Chen X, Kazim SF, Liu F, Gong CX, Grundke-Iqbal I, Iqbal K. Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies. Journal of Neural Transmission (Vienna, Austria : 1996). 122: 607-17. PMID 25233799 DOI: 10.1007/S00702-014-1315-Y |
0.646 |
|
| 2014 |
Arif M, Wei J, Zhang Q, Liu F, Basurto-Islas G, Grundke-Iqbal I, Iqbal K. Cytoplasmic retention of protein phosphatase 2A inhibitor 2 (I2PP2A) induces Alzheimer-like abnormal hyperphosphorylation of Tau. The Journal of Biological Chemistry. 289: 27677-91. PMID 25128526 DOI: 10.1074/Jbc.M114.565358 |
0.684 |
|
| 2014 |
Arif M, Kazim SF, Grundke-Iqbal I, Garruto RM, Iqbal K. Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam. Proceedings of the National Academy of Sciences of the United States of America. 111: 1144-9. PMID 24395787 DOI: 10.1073/Pnas.1322614111 |
0.646 |
|
| 2014 |
Wang X, Blanchard J, Grundke-Iqbal I, Wegiel J, Deng HX, Siddique T, Iqbal K. Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection. Acta Neuropathologica. 127: 243-56. PMID 24136402 DOI: 10.1007/S00401-013-1175-9 |
0.603 |
|
| 2013 |
Basurto-Islas G, Grundke-Iqbal I, Tung YC, Liu F, Iqbal K. Activation of asparaginyl endopeptidase leads to Tau hyperphosphorylation in Alzheimer disease. The Journal of Biological Chemistry. 288: 17495-507. PMID 23640887 DOI: 10.1074/Jbc.M112.446070 |
0.669 |
|
| 2013 |
Jin N, Qian W, Yin X, Zhang L, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. CREB regulates the expression of neuronal glucose transporter 3: a possible mechanism related to impaired brain glucose uptake in Alzheimer's disease. Nucleic Acids Research. 41: 3240-56. PMID 23341039 DOI: 10.1093/nar/gks1227 |
0.512 |
|
| 2013 |
Cardenas-Aguayo Mdel C, Kazim SF, Grundke-Iqbal I, Iqbal K. Neurogenic and neurotrophic effects of BDNF peptides in mouse hippocampal primary neuronal cell cultures. Plos One. 8: e53596. PMID 23320097 DOI: 10.1371/Journal.Pone.0053596 |
0.486 |
|
| 2013 |
Chen Y, Liang Z, Blanchard J, Dai CL, Sun S, Lee MH, Grundke-Iqbal I, Iqbal K, Liu F, Gong CX. A non-transgenic mouse model (icv-STZ mouse) of Alzheimer's disease: similarities to and differences from the transgenic model (3xTg-AD mouse). Molecular Neurobiology. 47: 711-25. PMID 23150171 DOI: 10.1007/S12035-012-8375-5 |
0.586 |
|
| 2013 |
Wang JZ, Xia YY, Grundke-Iqbal I, Iqbal K. Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration. Journal of Alzheimer's Disease : Jad. 33: S123-39. PMID 22710920 DOI: 10.3233/Jad-2012-129031 |
0.682 |
|
| 2013 |
Arif M, Grundke-Iqbal I, Iqbal K. P3-042: β-N-Methylamino-L-alanine could be involved in Alzheimer's neurofibrillary pathology in amyotrophic lateral sclerosis-Parkinsonism dementia complex Alzheimer's & Dementia. 9: P566-P566. DOI: 10.1016/J.Jalz.2013.05.1111 |
0.522 |
|
| 2013 |
Kazim SF, Blanchard J, Dai C, Tung Y, Grundke-Iqbal I, Iqbal K. O3-13-02: Chronic treatment with a CNTF-derived peptide reverses dendritic and synaptic plasticity deficits, cognitive impairment and tau pathology in an Alzheimer's disease mouse model Alzheimer's & Dementia. 9: P548-P548. DOI: 10.1016/J.Jalz.2013.04.310 |
0.548 |
|
| 2012 |
Chen Y, Tian Z, Liang Z, Sun S, Dai CL, Lee MH, LaFerla FM, Grundke-Iqbal I, Iqbal K, Liu F, Gong CX. Brain gene expression of a sporadic (icv-STZ Mouse) and a familial mouse model (3xTg-AD mouse) of Alzheimer's disease. Plos One. 7: e51432. PMID 23236499 DOI: 10.1371/Journal.Pone.0051432 |
0.566 |
|
| 2012 |
Liu Y, Li X, Yu Y, Shi J, Liang Z, Run X, Li Y, Dai CL, Grundke-Iqbal I, Iqbal K, Liu F, Gong CX. Developmental regulation of protein O-GlcNAcylation, O-GlcNAc transferase, and O-GlcNAcase in mammalian brain. Plos One. 7: e43724. PMID 22928023 DOI: 10.1371/Journal.Pone.0043724 |
0.475 |
|
| 2012 |
Yin X, Jin N, Gu J, Shi J, Zhou J, Gong CX, Iqbal K, Grundke-Iqbal I, Liu F. Dual-specificity tyrosine phosphorylation-regulated kinase 1A (Dyrk1A) modulates serine/arginine-rich protein 55 (SRp55)-promoted Tau exon 10 inclusion. The Journal of Biological Chemistry. 287: 30497-506. PMID 22767602 DOI: 10.1074/Jbc.M112.355412 |
0.626 |
|
| 2012 |
Shi J, Wu S, Dai CL, Li Y, Grundke-Iqbal I, Iqbal K, Liu F, Gong CX. Diverse regulation of AKT and GSK-3β by O-GlcNAcylation in various types of cells. Febs Letters. 586: 2443-50. PMID 22687243 DOI: 10.1016/J.Febslet.2012.05.063 |
0.506 |
|
| 2012 |
Yu Y, Zhang L, Li X, Run X, Liang Z, Li Y, Liu Y, Lee MH, Grundke-Iqbal I, Iqbal K, Vocadlo DJ, Liu F, Gong CX. Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation. Plos One. 7: e35277. PMID 22536363 DOI: 10.1371/Journal.Pone.0035277 |
0.665 |
|
| 2012 |
Bolognin S, Blanchard J, Wang X, Basurto-Islas G, Tung YC, Kohlbrenner E, Grundke-Iqbal I, Iqbal K. An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide. Acta Neuropathologica. 123: 133-51. PMID 22083255 DOI: 10.1007/S00401-011-0908-X |
0.575 |
|
| 2012 |
Ding S, Shi J, Qian W, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. Regulation of alternative splicing of tau exon 10 by 9G8 and Dyrk1A. Neurobiology of Aging. 33: 1389-99. PMID 21215488 DOI: 10.1016/J.Neurobiolaging.2010.11.021 |
0.612 |
|
| 2012 |
Jin N, Qian W, Yin X, Iqbal K, Grundke-Iqbal I, Gong C, Liu F. P2-081: CREB regulates the expression of neuronal glucose transporter 3: A mechanism leading to impaired brain glucose uptake in Alzheimer's disease Alzheimer's & Dementia. 8: P292-P292. DOI: 10.1016/J.Jalz.2012.05.785 |
0.509 |
|
| 2012 |
Liu F, Jin N, Shi J, Qian W, Yin X, Grundke-Iqbal I, Iqbal K, Gong C. O1-07-06: Truncation of GSK-3beta by calpain I contributes to the hyperphosphorylation of tau in the Alzheimer's brain Alzheimer's & Dementia. 8: P98-P98. DOI: 10.1016/J.Jalz.2012.05.244 |
0.586 |
|
| 2012 |
Grundke-Iqbal I, Bolognin S, Wang X, Blanchard J, Iqbal K. P4-224: Rescue of cognitive impairment and neuronal plasticity with a neurotrophic peptide in a rat model of sporadic Alzheimer's disease Alzheimer's & Dementia. 8: P713-P714. DOI: 10.1016/J.Jalz.2012.05.1929 |
0.511 |
|
| 2012 |
Shi J, Gu J, Grundke-Iqbal I, Iqbal K, Liu F, Gong C. P4-045: Cerebral ischemia-induced elevation of O-GlcNAcylation causes AKT inhibition and apoptosis Alzheimer's & Dementia. 8: P651-P651. DOI: 10.1016/J.Jalz.2012.05.1746 |
0.418 |
|
| 2012 |
Gong C, Liu F, Grundke-Iqbal I, Iqbal K. F3-02-02: O-GlcNAcylated tau: A link between impaired glucose metabolism and neurodegeneration in Alzheimer's disease Alzheimer's & Dementia. 8: P423-P423. DOI: 10.1016/J.Jalz.2012.05.1127 |
0.548 |
|
| 2011 |
Blanchard J, Bolognin S, Chohan MO, Rabe A, Iqbal K, Grundke-Iqbal I. Rescue of synaptic failure and alleviation of learning and memory impairments in a trisomic mouse model of down syndrome. Journal of Neuropathology and Experimental Neurology. 70: 1070-9. PMID 22082658 DOI: 10.1097/Nen.0B013E318236E9Ad |
0.467 |
|
| 2011 |
Iqbal K, Grundke-Iqbal I. Opportunities and challenges in developing Alzheimer disease therapeutics. Acta Neuropathologica. 122: 543-9. PMID 21959585 DOI: 10.1007/S00401-011-0878-Z |
0.586 |
|
| 2011 |
Rockenstein E, Ubhi K, Doppler E, Novak P, Moessler H, Li B, Blanchard J, Grundke-Iqbal I, Iqbal K, Mante M, Adame A, Crews L, Masliah E. Regional comparison of the neurogenic effects of CNTF-derived peptides and cerebrolysin in AβPP transgenic mice. Journal of Alzheimer's Disease : Jad. 27: 743-52. PMID 21860085 DOI: 10.3233/Jad-2011-110914 |
0.507 |
|
| 2011 |
Arnaud L, Chen S, Liu F, Li B, Khatoon S, Grundke-Iqbal I, Iqbal K. Mechanism of inhibition of PP2A activity and abnormal hyperphosphorylation of tau by I2(PP2A)/SET. Febs Letters. 585: 2653-9. PMID 21806989 DOI: 10.1016/J.Febslet.2011.07.020 |
0.583 |
|
| 2011 |
Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes. The Journal of Pathology. 225: 54-62. PMID 21598254 DOI: 10.1002/Path.2912 |
0.583 |
|
| 2011 |
Chalbot S, Zetterberg H, Blennow K, Fladby T, Andreasen N, Grundke-Iqbal I, Iqbal K. Blood-cerebrospinal fluid barrier permeability in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 505-15. PMID 21471645 DOI: 10.3233/Jad-2011-101959 |
0.596 |
|
| 2011 |
Qian W, Liang H, Shi J, Jin N, Grundke-Iqbal I, Iqbal K, Gong CX, Liu F. Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A. Nucleic Acids Research. 39: 6161-71. PMID 21470964 DOI: 10.1093/nar/gkr195 |
0.594 |
|
| 2011 |
Shi J, Qian W, Yin X, Iqbal K, Grundke-Iqbal I, Gu X, Ding F, Gong CX, Liu F. Cyclic AMP-dependent protein kinase regulates the alternative splicing of tau exon 10: a mechanism involved in tau pathology of Alzheimer disease. The Journal of Biological Chemistry. 286: 14639-48. PMID 21367856 DOI: 10.1074/Jbc.M110.204453 |
0.678 |
|
| 2011 |
Qian W, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. Splicing factor SC35 promotes tau expression through stabilization of its mRNA. Febs Letters. 585: 875-80. PMID 21333649 DOI: 10.1016/J.Febslet.2011.02.017 |
0.618 |
|
| 2011 |
Qian W, Yin X, Hu W, Shi J, Gu J, Grundke-Iqbal I, Iqbal K, Gong CX, Liu F. Activation of protein phosphatase 2B and hyperphosphorylation of Tau in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 23: 617-27. PMID 21157033 DOI: 10.3233/Jad-2010-100987 |
0.656 |
|
| 2011 |
Chohan MO, Li B, Blanchard J, Tung YC, Heaney AT, Rabe A, Iqbal K, Grundke-Iqbal I. Enhancement of dentate gyrus neurogenesis, dendritic and synaptic plasticity and memory by a neurotrophic peptide. Neurobiology of Aging. 32: 1420-34. PMID 19767127 DOI: 10.1016/J.Neurobiolaging.2009.08.008 |
0.444 |
|
| 2011 |
Bolognin S, Blanchard J, Wang X, Grundke-Iqbal I, Iqbal K. P4-252: Chronic treatment with an 11-mer CNTF peptide rescues synaptic deficit and cognitive impairment in a rat model of sporadic Alzheimer's disease Alzheimer's & Dementia. 7: S794-S794. DOI: 10.1016/J.Jalz.2011.05.2277 |
0.488 |
|
| 2011 |
Blanchard J, Iqbal K, Grundke-Iqbal I. P3-433: Improvement of cognition by enhancing neurogenesis and neuronal plasticity with a CNTF peptidergic compound Alzheimer's & Dementia. 7: S654-S654. DOI: 10.1016/J.Jalz.2011.05.1877 |
0.535 |
|
| 2011 |
del Carmen Cardenas-Aguayo M, Grundke-Iqbal I, Iqbal K. P3-423: Neurogenic and neuroprotective effects of BDNF peptides in mouse hippocampal primary neuronal cell cultures Alzheimer's & Dementia. 7: S651-S651. DOI: 10.1016/J.Jalz.2011.05.1867 |
0.444 |
|
| 2011 |
Shi J, Qian W, Yin X, Grundke-Iqbal I, Iqbal K, Gong C, Liu F. P3-139: Differential regulation of the alternative splicing of tau exon 10 by protein kinase A isoforms Alzheimer's & Dementia. 7: S560-S560. DOI: 10.1016/J.Jalz.2011.05.1579 |
0.58 |
|
| 2011 |
Basurto-Islas G, Grundke-Iqbal I, Iqbal K. P2-302: Asparagine Endopeptidase (AEP) is activated in Alzheimer's disease brain and induces I2PP2A cleavage Alzheimer's & Dementia. 7: S407-S407. DOI: 10.1016/J.Jalz.2011.05.1180 |
0.577 |
|
| 2010 |
Blanchard J, Chohan MO, Li B, Liu F, Iqbal K, Grundke-Iqbal I. Beneficial effect of a CNTF tetrapeptide on adult hippocampal neurogenesis, neuronal plasticity, and spatial memory in mice. Journal of Alzheimer's Disease : Jad. 21: 1185-95. PMID 20952820 DOI: 10.3233/Jad-2010-1000069 |
0.462 |
|
| 2010 |
Iqbal K, Grundke-Iqbal I. Alzheimer's disease, a multifactorial disorder seeking multitherapies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 420-4. PMID 20813343 DOI: 10.1016/J.Jalz.2010.04.006 |
0.583 |
|
| 2010 |
Blanchard J, Wanka L, Tung YC, Cárdenas-Aguayo Mdel C, LaFerla FM, Iqbal K, Grundke-Iqbal I. Pharmacologic reversal of neurogenic and neuroplastic abnormalities and cognitive impairments without affecting Aβ and tau pathologies in 3xTg-AD mice. Acta Neuropathologica. 120: 605-21. PMID 20697724 DOI: 10.1007/S00401-010-0734-6 |
0.586 |
|
| 2010 |
Iqbal K, Liu F, Gong CX, Grundke-Iqbal I. Tau in Alzheimer disease and related tauopathies. Current Alzheimer Research. 7: 656-64. PMID 20678074 DOI: 10.2174/156720510793611592 |
0.67 |
|
| 2010 |
Alonso AD, Di Clerico J, Li B, Corbo CP, Alaniz ME, Grundke-Iqbal I, Iqbal K. Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration. The Journal of Biological Chemistry. 285: 30851-60. PMID 20663882 DOI: 10.1074/Jbc.M110.110957 |
0.651 |
|
| 2010 |
Iqbal K, Wang X, Blanchard J, Liu F, Gong CX, Grundke-Iqbal I. Alzheimer's disease neurofibrillary degeneration: pivotal and multifactorial. Biochemical Society Transactions. 38: 962-6. PMID 20658985 DOI: 10.1042/Bst0380962 |
0.64 |
|
| 2010 |
Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden RM, Radu A, Grundke-Iqbal I, Iqbal K. The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 4420-32. PMID 20651003 DOI: 10.1096/Fj.10-158477 |
0.625 |
|
| 2010 |
Li B, Wanka L, Blanchard J, Liu F, Chohan MO, Iqbal K, Grundke-Iqbal I. Neurotrophic peptides incorporating adamantane improve learning and memory, promote neurogenesis and synaptic plasticity in mice. Febs Letters. 584: 3359-65. PMID 20600002 DOI: 10.1016/J.Febslet.2010.06.025 |
0.453 |
|
| 2010 |
Chalbot S, Zetterberg H, Blennow K, Fladby T, Grundke-Iqbal I, Iqbal K. Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity: a biomarker of blood-cerebrospinal fluid barrier permeability. Neuroscience Letters. 478: 179-83. PMID 20470866 DOI: 10.1016/J.Neulet.2010.05.012 |
0.489 |
|
| 2010 |
Gong CX, Grundke-Iqbal I, Iqbal K. Targeting tau protein in Alzheimer's disease. Drugs & Aging. 27: 351-65. PMID 20450234 DOI: 10.2165/11536110-000000000-00000 |
0.668 |
|
| 2010 |
Qian W, Shi J, Yin X, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. PP2A regulates tau phosphorylation directly and also indirectly via activating GSK-3beta. Journal of Alzheimer's Disease : Jad. 19: 1221-9. PMID 20308788 DOI: 10.3233/Jad-2010-1317 |
0.655 |
|
| 2010 |
Blanchard J, Iqbal K, Grundke-Iqbal I. S4-03-06: Reversal Of Cognitive Impairment By Pharmacologic Neuroregeneration: A Novel Therapeutic Approach Alzheimer's & Dementia. 6: e14-e14. DOI: 10.1016/J.Jalz.2010.08.045 |
0.412 |
|
| 2010 |
Yin X, Shi J, Grundke-Iqbal I, Iqbal K, Gong C, Liu F. P1-350: Overexpression of Dyrk1A dysregulates the alternative splicing of tau exon 10 Alzheimer's & Dementia. 6: S274-S274. DOI: 10.1016/J.Jalz.2010.05.903 |
0.566 |
|
| 2010 |
Liu F, Shi J, Qian W, Yin X, Grundke-Iqbal I, Iqbal K, Gong C. Truncation of GSK-3β by activated calpain I in Alzheimer brain enhances its biological activity Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.887 |
0.516 |
|
| 2010 |
Blanchard J, Iqbal K, Grundke-Iqbal I. P1-186: Chronic treatment with a CNTF peptide enhances neuronal plasticity and alleviates cognitive impairment in 3xTgAD mice Alzheimer's & Dementia. 6: S227-S228. DOI: 10.1016/J.Jalz.2010.05.736 |
0.429 |
|
| 2010 |
Wang X, Blanchard J, Grundke-Iqbal I, Iqbal K. S5-01-05: A novel etiopathogenic mechanism and a disease-relevant non-transgenic rat model of Alzheimer's disease Alzheimer's & Dementia. 6: S167-S167. DOI: 10.1016/J.Jalz.2010.05.520 |
0.518 |
|
| 2010 |
Iqbal K, Wang X, Blanchard J, Grundke-Iqbal I. O4-04-04: A protein phosphatase-2A-based etiopathogenic mechanism of Alzheimer's disease Alzheimer's & Dementia. 6: S155-S155. DOI: 10.1016/J.Jalz.2010.05.484 |
0.538 |
|
| 2010 |
Grundke-Iqbal I, Blanchard J, Chohan MO, Rabe A, Iqbal K. P3-355: Chronic treatment with a CNTF peptide restores neurogenesis and alleviates memory deficit in Ts65Dn mice Alzheimer's & Dementia. 6: S556-S556. DOI: 10.1016/J.Jalz.2010.05.1897 |
0.412 |
|
| 2010 |
Li X, Yu Y, Blanchard J, Liu Y, Iqbal K, Grundke-Iqbal I, Gong C. P3-340: Molecular basis of cognitive improvement of pioglitazone and rosiglitazone Alzheimer's & Dementia. 6: S552-S552. DOI: 10.1016/J.Jalz.2010.05.1841 |
0.405 |
|
| 2010 |
Shi J, Yin X, Iqbal K, Grundke-Iqbal I, Liu F, Gong C. P2-308: Regulation of Akt by O-GlcNAcylation in various cell types: implication in Alzheimer's Disease Alzheimer's & Dementia. 6: S403-S404. DOI: 10.1016/J.Jalz.2010.05.1359 |
0.538 |
|
| 2010 |
Gong C, Liu Y, Deng Y, Liu F, Grundke-Iqbal I, Iqbal K. P2-245: Dysregulation of brain insulin signaling: A mechanistic link between diabetes and Alzheimer's disease Alzheimer's & Dementia. 6: S386-S386. DOI: 10.1016/J.Jalz.2010.05.1294 |
0.508 |
|
| 2009 |
Chalbot S, Zetterberg H, Blennow K, Fladby T, Grundke-Iqbal I, Iqbal K. Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease. Clinical Chemistry. 55: 2171-9. PMID 19850632 DOI: 10.1373/Clinchem.2009.130286 |
0.51 |
|
| 2009 |
Deng Y, Li B, Liu Y, Iqbal K, Grundke-Iqbal I, Gong CX. Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease. The American Journal of Pathology. 175: 2089-98. PMID 19815707 DOI: 10.2353/Ajpath.2009.090157 |
0.608 |
|
| 2009 |
Liu Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. Brain glucose transporters, O-GlcNAcylation and phosphorylation of tau in diabetes and Alzheimer's disease. Journal of Neurochemistry. 111: 242-9. PMID 19659459 DOI: 10.1111/J.1471-4159.2009.06320.X |
0.623 |
|
| 2009 |
Tanimukai H, Kudo T, Tanaka T, Grundke-Iqbal I, Iqbal K, Takeda M. Novel therapeutic strategies for neurodegenerative disease. Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society. 9: 103-9. PMID 19604333 DOI: 10.1111/J.1479-8301.2009.00289.X |
0.644 |
|
| 2009 |
Liu F, Shi J, Tanimukai H, Gu J, Gu J, Grundke-Iqbal I, Iqbal K, Gong CX. Reduced O-GlcNAcylation links lower brain glucose metabolism and tau pathology in Alzheimer's disease. Brain : a Journal of Neurology. 132: 1820-32. PMID 19451179 DOI: 10.1093/Brain/Awp099 |
0.651 |
|
| 2009 |
Liang Z, Liu F, Iqbal K, Grundke-Iqbal I, Gong CX. Dysregulation of tau phosphorylation in mouse brain during excitotoxic damage. Journal of Alzheimer's Disease : Jad. 17: 531-9. PMID 19363259 DOI: 10.3233/Jad-2009-1069 |
0.687 |
|
| 2009 |
Run X, Liang Z, Zhang L, Iqbal K, Grundke-Iqbal I, Gong CX. Anesthesia induces phosphorylation of tau. Journal of Alzheimer's Disease : Jad. 16: 619-26. PMID 19276556 DOI: 10.3233/Jad-2009-1003 |
0.668 |
|
| 2009 |
Iqbal K, Liu F, Gong CX, Alonso Adel C, Grundke-Iqbal I. Mechanisms of tau-induced neurodegeneration. Acta Neuropathologica. 118: 53-69. PMID 19184068 DOI: 10.1007/S00401-009-0486-3 |
0.696 |
|
| 2009 |
Yu Y, Run X, Liang Z, Li Y, Liu F, Liu Y, Iqbal K, Grundke-Iqbal I, Gong CX. Developmental regulation of tau phosphorylation, tau kinases, and tau phosphatases. Journal of Neurochemistry. 108: 1480-94. PMID 19183272 DOI: 10.1111/J.1471-4159.2009.05882.X |
0.682 |
|
| 2009 |
Grundke-Iqbal I, Chohan MO, Li B, Blanchard J, Wanka L, Iqbal K. O3-06-08: Development of neurotrophic peptides for enhancement of neurogenesis and associated behavioral improvement Alzheimer's & Dementia. 5: P139-P139. DOI: 10.1016/J.Jalz.2009.05.473 |
0.417 |
|
| 2009 |
Iqbal K, Wang X, Blanchard J, Grundke-Iqbal I. O3-05-03: Overexpression of inhibitor-1 or -2 of protein phosphatase-2A causes abnormal hyperphosphorylation of tau and cognitive impairment in the rat Alzheimer's & Dementia. 5: P135-P135. DOI: 10.1016/J.Jalz.2009.05.459 |
0.529 |
|
| 2009 |
Liu F, Shi J, Qian W, Yin X, Grundke-Iqbal I, Iqbal K, Gong C. O3-05-01: Truncation and activation of Dyrk1A in Alzheimer's disease brain by activated calpain I Alzheimer's & Dementia. 5: P134-P135. DOI: 10.1016/J.Jalz.2009.05.457 |
0.556 |
|
| 2009 |
Rockenstein E, Doppler E, Moessler H, Li B, Blanchard J, Grundke-Iqbal I, Iqbal K, Mante M, Adame A, Masliah E. P4-030: Development of neuropeptides that promote neurogenesis in models of Alzheimer's and Parkinson's disease Alzheimer's & Dementia. 5: P440-P440. DOI: 10.1016/J.Jalz.2009.04.900 |
0.517 |
|
| 2009 |
Liang Z, Liu F, Iqbal K, Grundke-Iqbal I, Gong C. P3-178: Excitotoxic damage deregulates tau phosphorylation: Implication to Alzheimer's disease Alzheimer's & Dementia. 5: P396-P396. DOI: 10.1016/J.Jalz.2009.04.1052 |
0.643 |
|
| 2008 |
Iqbal K, Chohan MO, Grundke-Iqbal I. Stratification of patients is the way to go to develop neuroprotective/disease-modifying drugs for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 15: 339-45. PMID 18953118 DOI: 10.3233/Jad-2008-15215 |
0.619 |
|
| 2008 |
Alonso AC, Li B, Grundke-Iqbal I, Iqbal K. Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies. Current Alzheimer Research. 5: 375-84. PMID 18690834 DOI: 10.2174/156720508785132307 |
0.663 |
|
| 2008 |
Iqbal K, Alonso Adel C, Grundke-Iqbal I. Cytosolic abnormally hyperphosphorylated tau but not paired helical filaments sequester normal MAPs and inhibit microtubule assembly. Journal of Alzheimer's Disease : Jad. 14: 365-70. PMID 18688085 DOI: 10.3233/Jad-2008-14402 |
0.66 |
|
| 2008 |
Shi J, Zhang T, Zhou C, Chohan MO, Gu X, Wegiel J, Zhou J, Hwang YW, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. Increased dosage of Dyrk1A alters alternative splicing factor (ASF)-regulated alternative splicing of tau in Down syndrome. The Journal of Biological Chemistry. 283: 28660-9. PMID 18658135 DOI: 10.1074/Jbc.M802645200 |
0.618 |
|
| 2008 |
Liu F, Liang Z, Wegiel J, Hwang YW, Iqbal K, Grundke-Iqbal I, Ramakrishna N, Gong CX. Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3224-33. PMID 18509201 DOI: 10.1096/Fj.07-104539 |
0.645 |
|
| 2008 |
Liang Z, Liu F, Iqbal K, Grundke-Iqbal I, Wegiel J, Gong CX. Decrease of protein phosphatase 2A and its association with accumulation and hyperphosphorylation of tau in Down syndrome. Journal of Alzheimer's Disease : Jad. 13: 295-302. PMID 18430997 DOI: 10.3233/Jad-2008-13307 |
0.69 |
|
| 2008 |
Chen S, Li B, Grundke-Iqbal I, Iqbal K. I1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A. The Journal of Biological Chemistry. 283: 10513-21. PMID 18245083 DOI: 10.1074/Jbc.M709852200 |
0.617 |
|
| 2008 |
Wang XC, Zhang YC, Chatterjie N, Grundke-Iqbal I, Iqbal K, Wang JZ. Effect of melatonin and melatonylvalpromide on beta-amyloid and neurofilaments in N2a cells. Neurochemical Research. 33: 1138-44. PMID 18231852 DOI: 10.1007/S11064-007-9563-Y |
0.514 |
|
| 2008 |
Iqbal K, Grundke-Iqbal I. Alzheimer neurofibrillary degeneration: significance, etiopathogenesis, therapeutics and prevention. Journal of Cellular and Molecular Medicine. 12: 38-55. PMID 18194444 DOI: 10.1111/j.1582-4934.2008.00225.x |
0.662 |
|
| 2008 |
Liu Y, Liu F, Iqbal K, Grundke-Iqbal I, Gong CX. Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease. Febs Letters. 582: 359-64. PMID 18174027 DOI: 10.1016/J.Febslet.2007.12.035 |
0.584 |
|
| 2008 |
Li B, Yamamori H, Tatebayashi Y, Shafit-Zagardo B, Tanimukai H, Chen S, Iqbal K, Grundke-Iqbal I. Failure of neuronal maturation in Alzheimer disease dentate gyrus. Journal of Neuropathology and Experimental Neurology. 67: 78-84. PMID 18091557 DOI: 10.1097/Nen.0B013E318160C5Db |
0.523 |
|
| 2008 |
Deng Y, Li B, Liu F, Iqbal K, Grundke-Iqbal I, Brandt R, Gong CX. Regulation between O-GlcNAcylation and phosphorylation of neurofilament-M and their dysregulation in Alzheimer disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 138-45. PMID 17687114 DOI: 10.1096/Fj.07-8309Com |
0.539 |
|
| 2008 |
Grundke-Iqbal I, Chohan MO, Li B, Blanchard J, Iqbal K. O4-04-08: Improvement of cognition with a neurogenic/neurotrophic peptide Alzheimer's & Dementia. 4: T193-T193. DOI: 10.1016/J.Jalz.2008.05.534 |
0.417 |
|
| 2008 |
Liu Y, Liu F, Iqbal K, Grundke-Iqbal I, Gong C. O4-02-05: Molecular mechanism by which type 2 diabetes mellitus increases the risk for Alzheimer's disease Alzheimer's & Dementia. 4: T187-T187. DOI: 10.1016/J.Jalz.2008.05.513 |
0.471 |
|
| 2008 |
Gong C, Liu F, Liu Y, Deng Y, Grundke-Iqbal I, Iqbal K. O2-05-08: Protein O-Glcnacylation: A novel mechanism involved in Alzheimer's disease Alzheimer's & Dementia. 4: T143-T143. DOI: 10.1016/J.Jalz.2008.05.347 |
0.502 |
|
| 2008 |
Chalbot S, Blennow K, Grundke-Iqbal I, Iqbal K. P3-063: CSF phospholipase A2 activity is a biomarker of blood brain barrier permeability but not Alzheimer's disease Alzheimer's & Dementia. 4: T536-T536. DOI: 10.1016/J.Jalz.2008.05.1627 |
0.558 |
|
| 2008 |
Li B, Chohan MO, Blanchard J, Iqbal K, Grundke-Iqbal I. P2-445: Enhancement of dentate gyrus neurogenesis and associated memory by a neurotrophic peptide Alzheimer's & Dementia. 4: T504-T504. DOI: 10.1016/J.Jalz.2008.05.1524 |
0.426 |
|
| 2008 |
Liang H, Shi J, Iqbal K, Grundke-Iqbal I, Gong C, Liu F. P2-155: Phosphorylation of SC35 by Dyrk1A inhibits its promotion of tau exon 10 inclusion Alzheimer's & Dementia. 4: T416-T416. DOI: 10.1016/J.Jalz.2008.05.1229 |
0.594 |
|
| 2008 |
Yin X, Jin N, Shi J, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. P2-147: Modulation of SRp55-regulated alternative splicing of tau exon 10 by Dyrk1A Alzheimer's & Dementia. 4: T413-T413. DOI: 10.1016/J.Jalz.2008.05.1220 |
0.539 |
|
| 2008 |
Shi J, Gu Q, Wang W, Iqbal K, Grundke-Iqbal I, Gong CX, Liu F. P2-145: Regulation of ASF-mediated alternative splicing of tau exon 10 by PKA Alzheimer's & Dementia. 4: T413-T413. DOI: 10.1016/J.Jalz.2008.05.1218 |
0.572 |
|
| 2008 |
Liang Z, Liu F, Iqbal K, Grundke-Iqbal I, Wegiel J, Gong C. P2-142: Decreased protein phosphatase 2A in Down syndrome brain: A cause of neurofibrillary degeneration Alzheimer's & Dementia. 4: T412-T412. DOI: 10.1016/J.Jalz.2008.05.1215 |
0.511 |
|
| 2007 |
Liu F, Li B, Tung EJ, Grundke-Iqbal I, Iqbal K, Gong CX. Site-specific effects of tau phosphorylation on its microtubule assembly activity and self-aggregation. The European Journal of Neuroscience. 26: 3429-36. PMID 18052981 DOI: 10.1111/J.1460-9568.2007.05955.X |
0.629 |
|
| 2007 |
Liang Z, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. Down-regulation of cAMP-dependent protein kinase by over-activated calpain in Alzheimer disease brain. Journal of Neurochemistry. 103: 2462-70. PMID 17908236 DOI: 10.1111/J.1471-4159.2007.04942.X |
0.591 |
|
| 2007 |
Iqbal K, Grundke-Iqbal I. Developing pharmacological therapies for Alzheimer disease. Cellular and Molecular Life Sciences : Cmls. 64: 2234-44. PMID 17604997 DOI: 10.1007/s00018-007-7221-9 |
0.606 |
|
| 2007 |
Yamamori H, Khatoon S, Grundke-Iqbal I, Blennow K, Ewers M, Hampel H, Iqbal K. Tau in cerebrospinal fluid: a sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification. Neuroscience Letters. 418: 186-9. PMID 17400380 DOI: 10.1016/J.Neulet.2007.03.022 |
0.587 |
|
| 2007 |
Li B, Chohan MO, Grundke-Iqbal I, Iqbal K. Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau. Acta Neuropathologica. 113: 501-11. PMID 17372746 DOI: 10.1007/S00401-007-0207-8 |
0.647 |
|
| 2007 |
Wang JZ, Grundke-Iqbal I, Iqbal K. Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration. The European Journal of Neuroscience. 25: 59-68. PMID 17241267 DOI: 10.1111/J.1460-9568.2006.05226.X |
0.686 |
|
| 2007 |
Chen H, Tung YC, Li B, Iqbal K, Grundke-Iqbal I. Trophic factors counteract elevated FGF-2-induced inhibition of adult neurogenesis. Neurobiology of Aging. 28: 1148-62. PMID 16859812 DOI: 10.1016/J.Neurobiolaging.2006.05.036 |
0.492 |
|
| 2007 |
Iqbal K, Grundke-Iqbal I. Alzheimer subgroups: Towards effective drug development Future Neurology. 2: 3-6. DOI: 10.2217/14796708.2.1.3 |
0.455 |
|
| 2007 |
Iqbal K, Grundke-Iqbal I. O2-01-06: Inhibition of more than one tau kinase might be required for prevention of Alzheimer disease Alzheimer's & Dementia. 3: S183-S184. DOI: 10.1016/J.Jalz.2007.04.049 |
0.618 |
|
| 2006 |
Grundke-Iqbal I, Rolkova G, Konstekova E, Iqbal K. Biological markers in Alzheimer's disease. Bratislavskã© Lekã¡Rske Listy. 107: 359-65. PMID 17262988 |
0.545 |
|
| 2006 |
Sengupta A, Grundke-Iqbal I, Iqbal K. Regulation of phosphorylation of tau by protein kinases in rat brain. Neurochemical Research. 31: 1473-80. PMID 17120162 DOI: 10.1016/S0197-4580(00)82474-4 |
0.657 |
|
| 2006 |
Liu F, Liang Z, Shi J, Yin D, El-Akkad E, Grundke-Iqbal I, Iqbal K, Gong CX. PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners. Febs Letters. 580: 6269-74. PMID 17078951 DOI: 10.1016/J.Febslet.2006.10.033 |
0.579 |
|
| 2006 |
Gong CX, Liu F, Grundke-Iqbal I, Iqbal K. Dysregulation of protein phosphorylation/dephosphorylation in Alzheimer's disease: a therapeutic target. Journal of Biomedicine & Biotechnology. 2006: 31825. PMID 17047304 DOI: 10.1155/Jbb/2006/31825 |
0.662 |
|
| 2006 |
Sengupta A, Novak M, Grundke-Iqbal I, Iqbal K. Regulation of phosphorylation of tau by cyclin-dependent kinase 5 and glycogen synthase kinase-3 at substrate level. Febs Letters. 580: 5925-33. PMID 17045592 DOI: 10.1016/J.Febslet.2006.09.060 |
0.653 |
|
| 2006 |
Iqbal K, Grundke-Iqbal I. Discoveries of tau, abnormally hyperphosphorylated tau and others of neurofibrillary degeneration: a personal historical perspective. Journal of Alzheimer's Disease : Jad. 9: 219-42. PMID 16914861 |
0.623 |
|
| 2006 |
Alonso Adel C, Li B, Grundke-Iqbal I, Iqbal K. Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity. Proceedings of the National Academy of Sciences of the United States of America. 103: 8864-9. PMID 16735465 DOI: 10.1073/Pnas.0603214103 |
0.674 |
|
| 2006 |
Gong CX, Liu F, Grundke-Iqbal I, Iqbal K. Impaired brain glucose metabolism leads to Alzheimer neurofibrillary degeneration through a decrease in tau O-GlcNAcylation. Journal of Alzheimer's Disease : Jad. 9: 1-12. PMID 16627930 DOI: 10.3233/Jad-2006-9101 |
0.642 |
|
| 2006 |
Zhou XW, Li X, Bjorkdahl C, Sjogren MJ, Alafuzoff I, Soininen H, Grundke-Iqbal I, Iqbal K, Winblad B, Pei JJ. Assessments of the accumulation severities of amyloid beta-protein and hyperphosphorylated tau in the medial temporal cortex of control and Alzheimer's brains. Neurobiology of Disease. 22: 657-68. PMID 16513361 DOI: 10.1016/J.Nbd.2006.01.006 |
0.659 |
|
| 2006 |
Rahman A, Grundke-Iqbal I, Iqbal K. PP2B isolated from human brain preferentially dephosphorylates Ser-262 and Ser-396 of the Alzheimer disease abnormally hyperphosphorylated tau. Journal of Neural Transmission (Vienna, Austria : 1996). 113: 219-30. PMID 15959850 DOI: 10.1007/S00702-005-0313-5 |
0.649 |
|
| 2006 |
Iqbal K, Khatoon S, Yamamori H, Grundke-Iqbal I. S4-01-01 Alzheimer's & Dementia. 2: S68. DOI: 10.1016/J.Jalz.2006.05.263 |
0.653 |
|
| 2006 |
Gong C, Liu F, Grundke-Iqbal I, Iqbal K. S3-03-01: O-glycosylation regulates phosphorylation of tau:A novel mechanism leading to neurofibrillarydegeneration in Alzheimer disease Alzheimer's & Dementia. 2: S48-S48. DOI: 10.1016/J.Jalz.2006.05.174 |
0.629 |
|
| 2006 |
Grundke-Iqbal I, Li B, Chohan MO, Tung YC, Iqbal K. P3-337: Enhancement of neurogenesis by peptides: A promising therapeutic approach Alzheimer's & Dementia. 2: S473-S474. DOI: 10.1016/J.Jalz.2006.05.1607 |
0.418 |
|
| 2006 |
Chen S, Grundke-Iqbal I, Iqbal K. P3-329: I1
PP2A
and I2
PP2A
affect tau phosphorylation via association with the catalytic subunit of protein phosphatase 2A Alzheimer's & Dementia. 2: S471-S471. DOI: 10.1016/J.Jalz.2006.05.1599 |
0.576 |
|
| 2006 |
Liang Z, Liu F, Hwang Y, Wegiel J, Iqbal K, Grundke-Iqbal I, Gong C. P3-304: Mnb/Dyrk1A primes phosphorylation of tau at several phosphorylation sites by GSK-3β Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1574 |
0.562 |
|
| 2006 |
Liu R, Björkdahl C, Zhou X, Alafuzoff I, Soininen H, Bogdanovic N, Iqbal K, Grundke-Iqbal I, Winblad BW, Wang J, Pei J. P3-300: Increased tyrosine 307 phosphorylation of protein phosphatase-2A correlates with tau associated pathologies in Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1569 |
0.617 |
|
| 2006 |
Khatoon S, Grundke-Iqbal I, Iqbal K. P3-292: High throughput screen assay to develop drugs for inhibition of abnormal hyperphosphorylation of tau Alzheimer's & Dementia. 2: S461-S461. DOI: 10.1016/J.Jalz.2006.05.1561 |
0.487 |
|
| 2006 |
Liu F, Grundke-Iqbal I, Iqbal K, Gong C. P3-248: Activation of calpain I in Alzheimer disease brain negatively regulates CREB Alzheimer's & Dementia. 2: S448-S448. DOI: 10.1016/J.Jalz.2006.05.1517 |
0.584 |
|
| 2006 |
Alonso AD, Li B, Grundke-Iqbal I, Iqbal K. O2-01-02: Treat abnormal hyperphosphorylation and not aggregation of tau Alzheimer's & Dementia. 2: S29-S30. DOI: 10.1016/J.Jalz.2006.05.103 |
0.545 |
|
| 2005 |
Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. The European Journal of Neuroscience. 22: 1942-50. PMID 16262633 DOI: 10.1111/J.1460-9568.2005.04391.X |
0.682 |
|
| 2005 |
Iqbal K, Flory M, Khatoon S, Soininen H, Pirttila T, Lehtovirta M, Alafuzoff I, Blennow K, Andreasen N, Vanmechelen E, Grundke-Iqbal I. Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers. Annals of Neurology. 58: 748-57. PMID 16247771 DOI: 10.1002/Ana.20639 |
0.594 |
|
| 2005 |
Liu F, Grundke-Iqbal I, Iqbal K, Oda Y, Tomizawa K, Gong CX. Truncation and activation of calcineurin A by calpain I in Alzheimer disease brain. The Journal of Biological Chemistry. 280: 37755-62. PMID 16150694 DOI: 10.1074/Jbc.M507475200 |
0.589 |
|
| 2005 |
Ruben GC, Wang JZ, Iqbal K, Grundke-Iqbal I. Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylation. Microscopy Research and Technique. 67: 175-95. PMID 16104003 DOI: 10.1002/Jemt.20197 |
0.455 |
|
| 2005 |
Iqbal K, Grundke-Iqbal I. Pharmacological approaches of neurofibrillary degeneration. Current Alzheimer Research. 2: 335-41. PMID 15974899 DOI: 10.2174/1567205054367810 |
0.689 |
|
| 2005 |
Tanimukai H, Grundke-Iqbal I, Iqbal K. Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease. The American Journal of Pathology. 166: 1761-71. PMID 15920161 DOI: 10.1016/S0002-9440(10)62486-8 |
0.653 |
|
| 2005 |
Rahman A, Grundke-Iqbal I, Iqbal K. Phosphothreonine-212 of Alzheimer abnormally hyperphosphorylated tau is a preferred substrate of protein phosphatase-1. Neurochemical Research. 30: 277-87. PMID 15895832 DOI: 10.1007/S11064-005-2483-9 |
0.626 |
|
| 2005 |
Iqbal K, Grundke-Iqbal I. Metabolic/signal transduction hypothesis of Alzheimer's disease and other tauopathies. Acta Neuropathologica. 109: 25-31. PMID 15645264 DOI: 10.1007/S00401-004-0951-Y |
0.631 |
|
| 2005 |
Tsujio I, Zaidi T, Xu J, Kotula L, Grundke-Iqbal I, Iqbal K. Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau. Febs Letters. 579: 363-72. PMID 15642345 DOI: 10.1016/J.Febslet.2004.11.097 |
0.597 |
|
| 2005 |
Sun L, Wang X, Liu S, Wang Q, Wang J, Bennecib M, Gong CX, Sengupta A, Grundke-Iqbal I, Iqbal K. Bilateral injection of isoproterenol into hippocampus induces Alzheimer-like hyperphosphorylation of tau and spatial memory deficit in rat. Febs Letters. 579: 251-8. PMID 15620722 DOI: 10.1016/J.Febslet.2004.11.083 |
0.636 |
|
| 2005 |
Iqbal K, Alonso Adel C, Chen S, Chohan MO, El-Akkad E, Gong CX, Khatoon S, Li B, Liu F, Rahman A, Tanimukai H, Grundke-Iqbal I. Tau pathology in Alzheimer disease and other tauopathies. Biochimica Et Biophysica Acta. 1739: 198-210. PMID 15615638 DOI: 10.1016/J.Bbadis.2004.09.008 |
0.686 |
|
| 2005 |
Chohan MO, Haque N, Alonso A, El-Akkad E, Grundke-Iqbal I, Grover A, Iqbal K. Hyperphosphorylation-induced self assembly of murine tau: a comparison with human tau. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 1035-47. PMID 15583961 DOI: 10.1007/s00702-004-0241-9 |
0.59 |
|
| 2005 |
Huang Y, Liu F, Grundke-Iqbal I, Iqbal K, Gong CX. NF-kappaB precursor, p105, and NF-kappaB inhibitor, IkappaBgamma, are both elevated in Alzheimer disease brain. Neuroscience Letters. 373: 115-8. PMID 15567564 DOI: 10.1016/J.Neulet.2004.09.074 |
0.552 |
|
| 2005 |
Liu F, Iqbal K, Grundke-Iqbal I, Rossie S, Gong CX. Dephosphorylation of tau by protein phosphatase 5: impairment in Alzheimer's disease. The Journal of Biological Chemistry. 280: 1790-6. PMID 15546861 DOI: 10.1074/Jbc.M410775200 |
0.687 |
|
| 2005 |
Gong CX, Liu F, Grundke-Iqbal I, Iqbal K. Post-translational modifications of tau protein in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 112: 813-38. PMID 15517432 DOI: 10.1007/s00702-004-0221-0 |
0.636 |
|
| 2005 |
Iqbal K, Flory M, Khatoon S, Soininen H, Pirttila T, Lehtovirta M, Blennow K, Andreasen N, Vanmechelen E, Grundke-Iqbal I. [O1-04-05]: Subgroups of Alzheimer disease based on cerebrospinal fluid levels of molecular markers Alzheimer's & Dementia. 1: S87-S87. DOI: 10.1016/J.Jalz.2005.06.304 |
0.513 |
|
| 2004 |
Huang Y, Tanimukai H, Liu F, Iqbal K, Grundke-Iqbal I, Gong CX. Elevation of the level and activity of acid ceramidase in Alzheimer's disease brain. The European Journal of Neuroscience. 20: 3489-97. PMID 15610181 DOI: 10.1111/J.1460-9568.2004.03852.X |
0.61 |
|
| 2004 |
Haque N, Gong CX, Sengupta A, Iqbal K, Grundke-Iqbal I. Regulation of microtubule-associated proteins, protein kinases and protein phosphatases during differentiation of SY5Y cells. Brain Research. Molecular Brain Research. 129: 163-70. PMID 15469892 DOI: 10.1016/J.Molbrainres.2004.07.001 |
0.595 |
|
| 2004 |
Liu SJ, Zhang JY, Li HL, Fang ZY, Wang Q, Deng HM, Gong CX, Grundke-Iqbal I, Iqbal K, Wang JZ. Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. The Journal of Biological Chemistry. 279: 50078-88. PMID 15375165 DOI: 10.1074/jbc.M406109200 |
0.622 |
|
| 2004 |
Iqbal K, Grundke-Iqbal I. Inhibition of neurofibrillary degeneration: a promising approach to Alzheimer's disease and other tauopathies. Current Drug Targets. 5: 495-502. PMID 15270196 DOI: 10.2174/1389450043345254 |
0.648 |
|
| 2004 |
Liu F, Iqbal K, Grundke-Iqbal I, Hart GW, Gong CX. O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 10804-9. PMID 15249677 DOI: 10.1073/Pnas.0400348101 |
0.661 |
|
| 2004 |
Tanimukai H, Grundke-Iqbal I, Iqbal K. Inhibitors of protein phosphatase-2A: topography and subcellular localization. Brain Research. Molecular Brain Research. 126: 146-56. PMID 15249138 DOI: 10.1016/J.Molbrainres.2004.04.003 |
0.504 |
|
| 2004 |
Alonso Adel C, Mederlyova A, Novak M, Grundke-Iqbal I, Iqbal K. Promotion of hyperphosphorylation by frontotemporal dementia tau mutations. The Journal of Biological Chemistry. 279: 34873-81. PMID 15190058 DOI: 10.1074/Jbc.M405131200 |
0.627 |
|
| 2004 |
Li L, Sengupta A, Haque N, Grundke-Iqbal I, Iqbal K. Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration. Febs Letters. 566: 261-9. PMID 15147906 DOI: 10.1016/J.Febslet.2004.04.047 |
0.6 |
|
| 2004 |
Tatebayashi Y, Haque N, Tung YC, Iqbal K, Grundke-Iqbal I. Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport. Journal of Cell Science. 117: 1653-63. PMID 15075227 DOI: 10.1242/Jcs.01018 |
0.613 |
|
| 2004 |
Gong CX, Liu F, Wu G, Rossie S, Wegiel J, Li L, Grundke-Iqbal I, Iqbal K. Dephosphorylation of microtubule-associated protein tau by protein phosphatase 5. Journal of Neurochemistry. 88: 298-310. PMID 14690518 DOI: 10.1111/J.1471-4159.2004.02147.X |
0.685 |
|
| 2004 |
Khatoon S, Grundke-Iqbal I, Iqbal K. P4-425 High throughput screen assays of inhibition of PP-2A catalyzed dephosphorylation of abnormally hyperphosphorylated tau by I1PP2A and I2PP2A Neurobiology of Aging. 25: S595. DOI: 10.1016/S0197-4580(04)81981-X |
0.512 |
|
| 2004 |
Rahman A, Grundke-Iqbal I, Iqbal K. P3-264 A novel phosphoseryl/phosphothreonyl protein phosphatase activity that might be involved in the abnormal hyperphosphorylation of tau Neurobiology of Aging. 25: S430. DOI: 10.1016/S0197-4580(04)81414-3 |
0.597 |
|
| 2004 |
Liu F, Iqbal K, Grundke-Iqbal I, Gong C. P3-263 Phosphorylation of tau is regulated by O-Glcnacylation Neurobiology of Aging. 25: S429. DOI: 10.1016/S0197-4580(04)81413-1 |
0.572 |
|
| 2004 |
Chohan MO, Alonso A, Haque N, El-Akkad E, Grundke-Iqbal I, Grover A, Iqbal K. P3-254 Hyperphosphorylation induced self-assembly of murine tau: a comparison with human tau Neurobiology of Aging. 25: S427. DOI: 10.1016/S0197-4580(04)81404-0 |
0.564 |
|
| 2004 |
Wang J, Liu S, Zhang J, Li H, Fang Z, Wang Q, Gong C, Grundke-Iqbal I, Iqbal K. P3-251 Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81401-5 |
0.568 |
|
| 2004 |
An W, Cowburn RF, Bjorkdahl C, Braak H, Alafuzoff I, Iqbal K, Grundke-Iqbal I, Winblad B. P3-246 Association of P70 S6 kinase with neurofibrillary degeneration in Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81396-4 |
0.567 |
|
| 2004 |
Chen S, Grundke-Iqbal I, Iqbal K. P3-240 I1PP2A and I2PP2A interact with the catalytic subunit of protein phosphatase 2A Neurobiology of Aging. 25: S423. DOI: 10.1016/S0197-4580(04)81390-3 |
0.451 |
|
| 2004 |
Tanimukai H, Grundke-Iqbal I, Iqbal K. P3-224 Inhibitors of protein phosphatase-2A colocalize with the abnormally hyperphosphorylated tau in Alzheimer disease Neurobiology of Aging. 25: S418-S419. DOI: 10.1016/S0197-4580(04)81374-5 |
0.621 |
|
| 2004 |
Li B, Liu F, Grundke-Iqbal I, Iqbal K. P2-129 Tau and a cell culture model of microtubule stability Neurobiology of Aging. 25: S261. DOI: 10.1016/S0197-4580(04)80876-5 |
0.523 |
|
| 2004 |
Haque N, Gong C, Sengupta A, Iqbal K, Grundke-Iqbal I. P2-128 Regulation of microtubule-associated proteins, protein kinases, and protein phosphatases during differentiation of SY5Y cells Neurobiology of Aging. 25: S261. DOI: 10.1016/S0197-4580(04)80875-3 |
0.524 |
|
| 2004 |
Chen H, Grundke-Iqbal I, Iqbal K. P1-358 Enhancement of neurogenesis by neurotrophic factors: a therapeutic approach to Alzheimer disease Neurobiology of Aging. 25: S200. DOI: 10.1016/S0197-4580(04)80670-5 |
0.519 |
|
| 2004 |
Huang Y, Iqbal K, Grundke-Iqbal I, Tanimukai H, Liu F, Gong C. P1-267 Alterations of glycoproteins in Alzheimer disease brain Neurobiology of Aging. 25: S172. DOI: 10.1016/S0197-4580(04)80580-3 |
0.577 |
|
| 2004 |
Pei JJ, An W, Cowburn RF, Grundke-Iqbal I, Iqbal K, Winblad B. S5-02-05 Involvement of aberrant regulation of PI3K and MAPK cascades in AD TAU phosphorylation Neurobiology of Aging. 25: S90. DOI: 10.1016/S0197-4580(04)80307-5 |
0.646 |
|
| 2004 |
Grundke-Iqbal I, Chen H, Li B, Tung Y, Tatebayashi Y, Iqbal K. O4-05-04 Regeneration of the brain: a promising approach to neurodegeneration and disorders of learning and memory Neurobiology of Aging. 25: S83. DOI: 10.1016/S0197-4580(04)80283-5 |
0.437 |
|
| 2004 |
Gong C, Liu F, Xu L, Wang J, Grundke-Iqbal I, Iqbal K. O2-05-06 Impaired glucose uptake/metabolism contributes to hyperphosphorylation of tau via reduction of O-GLCnacylation: a novel mechanism involved in Alzheimer disease Neurobiology of Aging. 25: S42. DOI: 10.1016/S0197-4580(04)80140-4 |
0.526 |
|
| 2004 |
Iqbal K, Grundke-Iqbal I. S2-04-02 Treatment of Alzheimer and other tauopathies by inhibition of neurofibrillary degeneration Neurobiology of Aging. 25: S30. DOI: 10.1016/S0197-4580(04)80098-8 |
0.543 |
|
| 2004 |
del Carmen Alonso A, Mederlyova A, Novak M, Grundke-Iqbal I, Iqbal K. S1-04-04 Mutations in tau gene lead to neurodegeneration by making tau a more favorable substrate for abnormal hyperphosphorylation Neurobiology of Aging. 25: S7-S8. DOI: 10.1016/S0197-4580(04)80025-3 |
0.568 |
|
| 2003 |
Pei JJ, Gong CX, An WL, Winblad B, Cowburn RF, Grundke-Iqbal I, Iqbal K. Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease. The American Journal of Pathology. 163: 845-58. PMID 12937126 DOI: 10.1016/S0002-9440(10)63445-1 |
0.63 |
|
| 2003 |
Hua Q, He RQ, Haque N, Qu MH, del Carmen Alonso A, Grundke-Iqbal I, Iqbal K. Microtubule associated protein tau binds to double-stranded but not single-stranded DNA. Cellular and Molecular Life Sciences : Cmls. 60: 413-21. PMID 12678504 DOI: 10.1007/S000180300034 |
0.514 |
|
| 2003 |
Gong CX, Wang JZ, Iqbal K, Grundke-Iqbal I. Inhibition of protein phosphatase 2A induces phosphorylation and accumulation of neurofilaments in metabolically active rat brain slices. Neuroscience Letters. 340: 107-10. PMID 12668248 DOI: 10.1016/S0304-3940(03)00096-X |
0.586 |
|
| 2003 |
Pei JJ, Khatoon S, An WL, Nordlinder M, Tanaka T, Braak H, Tsujio I, Takeda M, Alafuzoff I, Winblad B, Cowburn RF, Grundke-Iqbal I, Iqbal K. Role of protein kinase B in Alzheimer's neurofibrillary pathology. Acta Neuropathologica. 105: 381-92. PMID 12624792 DOI: 10.1007/S00401-002-0657-Y |
0.692 |
|
| 2003 |
Tatebayashi Y, Lee MH, Li L, Iqbal K, Grundke-Iqbal I. The dentate gyrus neurogenesis: a therapeutic target for Alzheimer's disease. Acta Neuropathologica. 105: 225-32. PMID 12557008 DOI: 10.1007/S00401-002-0636-3 |
0.543 |
|
| 2002 |
Wang J, Wang X, Liu R, Wang Q, Grundke-Iqbal I, Iqbal K. In vitro analysis of tau phosphorylation sites and its biological activity. Chinese Medical Sciences Journal = Chung-Kuo I Hsã¼Eh K'O Hsã¼Eh Tsa Chih / Chinese Academy of Medical Sciences. 17: 13-6. PMID 12894878 |
0.602 |
|
| 2002 |
Pei JJ, Braak H, An WL, Winblad B, Cowburn RF, Iqbal K, Grundke-Iqbal I. Up-regulation of mitogen-activated protein kinases ERK1/2 and MEK1/2 is associated with the progression of neurofibrillary degeneration in Alzheimer's disease. Brain Research. Molecular Brain Research. 109: 45-55. PMID 12531514 DOI: 10.1016/S0169-328X(02)00488-6 |
0.631 |
|
| 2002 |
Iqbal K, Alonso Adel C, El-Akkad E, Gong CX, Haque N, Khatoon S, Tsujio I, Grundke-Iqbal I. Pharmacological targets to inhibit Alzheimer neurofibrillary degeneration. Journal of Neural Transmission. Supplementum. 309-19. PMID 12456074 |
0.649 |
|
| 2002 |
Liu F, Zaidi T, Iqbal K, Grundke-Iqbal I, Gong CX. Aberrant glycosylation modulates phosphorylation of tau by protein kinase A and dephosphorylation of tau by protein phosphatase 2A and 5. Neuroscience. 115: 829-37. PMID 12435421 DOI: 10.1016/S0306-4522(02)00510-9 |
0.648 |
|
| 2002 |
Liu F, Iqbal K, Grundke-Iqbal I, Gong CX. Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta. Febs Letters. 530: 209-14. PMID 12387894 DOI: 10.1016/S0014-5793(02)03487-7 |
0.652 |
|
| 2002 |
Iqbal K, Grundke-Iqbal I. Neurofibrillary pathology leads to synaptic loss and not the other way around in Alzheimer disease. Journal of Alzheimer's Disease : Jad. 4: 235-8. PMID 12226542 DOI: 10.3233/Jad-2002-4313 |
0.54 |
|
| 2002 |
Iqbal K, Alonso Adel C, El-Akkad E, Gong CX, Haque N, Khatoon S, Pei JJ, Tsujio I, Wang JZ, Grundke-Iqbal I. Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion. Journal of Molecular Neuroscience : Mn. 19: 95-9. PMID 12212801 DOI: 10.1007/S12031-002-0017-3 |
0.685 |
|
| 2002 |
Pei JJ, Braak H, Gong CX, Grundke-Iqbal I, Iqbal K, Winblad B, Cowburn RF. Up-regulation of cell division cycle (cdc) 2 kinase in neurons with early stage Alzheimer's disease neurofibrillary degeneration. Acta Neuropathologica. 104: 369-76. PMID 12200623 DOI: 10.1007/S00401-002-0565-1 |
0.685 |
|
| 2002 |
Hu YY, He SS, Wang X, Duan QH, Grundke-Iqbal I, Iqbal K, Wang J. Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay. The American Journal of Pathology. 160: 1269-78. PMID 11943712 DOI: 10.1016/S0002-9440(10)62554-0 |
0.641 |
|
| 2002 |
Hu YY, He SS, Wang XC, Duan QH, Khatoon S, Iqbal K, Grundke-Iqbal I, Wang JZ. Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients. Neuroscience Letters. 320: 156-60. PMID 11852185 DOI: 10.1016/S0304-3940(02)00047-2 |
0.513 |
|
| 2002 |
Liu F, Zaidi T, Iqbal K, Grundke-Iqbal I, Merkle RK, Gong CX. Role of glycosylation in hyperphosphorylation of tau in Alzheimer's disease. Febs Letters. 512: 101-6. PMID 11852060 DOI: 10.1016/S0014-5793(02)02228-7 |
0.703 |
|
| 2001 |
Pei JJ, Braak E, Braak H, Grundke-Iqbal I, Iqbal K, Winblad B, Cowburn RF. Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration. Journal of Alzheimer's Disease : Jad. 3: 41-48. PMID 12214071 DOI: 10.3233/Jad-2001-3107 |
0.659 |
|
| 2001 |
Vijayan S, El-Akkad E, Grundke-Iqbal I, Iqbal K. A pool of beta-tubulin is hyperphosphorylated at serine residues in Alzheimer disease brain. Febs Letters. 509: 375-81. PMID 11749959 DOI: 10.1016/S0014-5793(01)03201-X |
0.644 |
|
| 2001 |
Wang J, Tung YC, Wang Y, Li XT, Iqbal K, Grundke-Iqbal I. Hyperphosphorylation and accumulation of neurofilament proteins in Alzheimer disease brain and in okadaic acid-treated SY5Y cells. Febs Letters. 507: 81-7. PMID 11682063 DOI: 10.1016/S0014-5793(01)02944-1 |
0.58 |
|
| 2001 |
Alonso AD, Zaidi T, Novak M, Barra HS, Grundke-Iqbal I, Iqbal K. Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein. The Journal of Biological Chemistry. 276: 37967-73. PMID 11495914 DOI: 10.1074/jbc.M105365200 |
0.638 |
|
| 2001 |
Cheng LY, Wang JZ, Gong CX, Pei JJ, Zaidi T, Grundke-Iqbal I, Iqbal K. Multiple forms of phosphatase from human brain: isolation and partial characterization of affi-gel blue nonbinding phosphatase activities. Neurochemical Research. 26: 425-38. PMID 11495355 DOI: 10.1023/A:1010963401453 |
0.513 |
|
| 2001 |
Alonso A, Zaidi T, Novak M, Grundke-Iqbal I, Iqbal K. Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proceedings of the National Academy of Sciences of the United States of America. 98: 6923-8. PMID 11381127 DOI: 10.1073/Pnas.121119298 |
0.621 |
|
| 2001 |
Sato Y, Naito Y, Grundke-Iqbal I, Iqbal K, Endo T. Analysis of N-glycans of pathological tau: possible occurrence of aberrant processing of tau in Alzheimer's disease. Febs Letters. 496: 152-60. PMID 11356201 DOI: 10.1016/S0014-5793(01)02421-8 |
0.665 |
|
| 2001 |
Gong CX, Lidsky T, Wegiel J, Grundke-Iqbal I, Iqbal K. Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain. Brain Research. Brain Research Protocols. 6: 134-40. PMID 11223412 DOI: 10.1016/S1385-299X(00)00046-5 |
0.638 |
|
| 2001 |
Bennecib M, Gong CX, Grundke-Iqbal I, Iqbal K. Inhibition of PP-2A upregulates CaMKII in rat forebrain and induces hyperphosphorylation of tau at Ser 262/356. Febs Letters. 490: 15-22. PMID 11172803 DOI: 10.1016/S0014-5793(01)02127-5 |
0.581 |
|
| 2000 |
Wang J, Wei Z, Wang Q, Grundke-Iqbal I, Iqbal K. [Association of microtubule promoting and binding activity of tau with its phosphorylation sites]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae. 22: 120-3. PMID 12903511 |
0.6 |
|
| 2000 |
Iqbal K, Grundke-Iqbal I. Alzheimer disease is multifactorial and heterogeneous. Neurobiology of Aging. 21: 901-2; discussion 90. PMID 11124439 DOI: 10.1016/S0197-4580(00)00191-3 |
0.558 |
|
| 2000 |
Bennecib M, Gong CX, Grundke-Iqbal I, Iqbal K. Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain. Febs Letters. 485: 87-93. PMID 11086171 DOI: 10.1016/S0014-5793(00)02203-1 |
0.629 |
|
| 2000 |
Iqbal K, Alonso AD, Gondal JA, Gong CX, Haque N, Khatoon S, Sengupta A, Wang JZ, Grundke-Iqbal I. Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach. Journal of Neural Transmission. Supplementum. 59: 213-22. PMID 10961432 DOI: 10.1007/978-3-7091-6781-6_22 |
0.681 |
|
| 2000 |
Tsujio I, Tanaka T, Kudo T, Nishikawa T, Shinozaki K, Grundke-Iqbal I, Iqbal K, Takeda M. Inactivation of glycogen synthase kinase-3 by protein kinase C delta: implications for regulation of tau phosphorylation. Febs Letters. 469: 111-7. PMID 10708767 DOI: 10.1016/S0014-5793(00)01234-5 |
0.57 |
|
| 2000 |
Cheng LY, Wang JZ, Gong CX, Pei JJ, Zaidi T, Grundke-Iqbal I, Iqbal K. Multiple forms of phosphatase from human brain: isolation and partial characterization of affi-gel blue binding phosphatases. Neurochemical Research. 25: 107-20. PMID 10685610 |
0.522 |
|
| 2000 |
Gong CX, Lidsky T, Wegiel J, Zuck L, Grundke-Iqbal I, Iqbal K. Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer's disease. The Journal of Biological Chemistry. 275: 5535-44. PMID 10681533 DOI: 10.1074/Jbc.275.8.5535 |
0.696 |
|
| 2000 |
Gong CX, Wegiel J, Lidsky T, Zuck L, Avila J, Wisniewski HM, Grundke-Iqbal I, Iqbal K. Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain. Brain Research. 853: 299-309. PMID 10640627 DOI: 10.1016/S0006-8993(99)02294-5 |
0.578 |
|
| 2000 |
He S, Hu Y, Grundke-Iqbal I, Iqbal K, Wang J. Development of an ultrasensitive elisa-double enzyme amplification assay and quantitation of total and abnormally hyperphosphorylated taus in cerebrospinal fluid Neurobiology of Aging. 21: 228. DOI: 10.1016/S0197-4580(00)83359-X |
0.504 |
|
| 2000 |
Grundke-Iqbal I, Tatebayashi Y, Gong C, Zhong J, Haque N, Iqbal K. Role of protein kinases, protein phosphatases and extracellular signals in the abnormal hyperphosphorylation of tau Neurobiology of Aging. 21: 210. DOI: 10.1016/S0197-4580(00)83273-X |
0.572 |
|
| 2000 |
Wang J, Tung YC, Wang Y, Iqbal K, Grundke-Iqbal I. Hyperphosphorylation and accumulation of neurofilament protein subunits in Alzheimer disease brain Neurobiology of Aging. 21: 273. DOI: 10.1016/S0197-4580(00)83181-4 |
0.6 |
|
| 2000 |
Tatebayashi Y, Lee MH, Iqbal K, Grundke-Iqbal I. The peptidergic antidementia drug cerebrolysin increases neurogenesis in the adult rat dentate gyrus and improves spatial learning and memory Neurobiology of Aging. 21: 42. DOI: 10.1016/S0197-4580(00)82863-8 |
0.392 |
|
| 2000 |
Khatoon S, Soininen H, Lehtovirta M, Alafuzoff II, Vanmechelen EJ, Grundke-Iqbal I, Iqbal K. Subgroups of Alzheimer disease based on levels of CSF tau, ubiquitin and Aβ1−42 Neurobiology of Aging. 21: 31. DOI: 10.1016/S0197-4580(00)82814-6 |
0.62 |
|
| 2000 |
Liu F, Zaidi T, Iqbal K, Grundke-Iqbal I, Gong C. Glycosylation of tau protein occurs earlier than its hyperphosphorylation in Alzheimer's disease Neurobiology of Aging. 21: 16. DOI: 10.1016/S0197-4580(00)82749-9 |
0.643 |
|
| 2000 |
Gong C, Lidsky T, Wegiel J, Grundke-Iqbal I, Iqbal K. Metabolically active rat brain slices as a model for studying neurofibrillary degeneration of Alzheimer's disease Neurobiology of Aging. 21: 10. DOI: 10.1016/S0197-4580(00)82722-0 |
0.56 |
|
| 2000 |
Vijayan S, Grundke-Iqbal I, Iqbal K. Abnormal hyperphosphorylation of non-tau proteins in Alzheimer's disease brain Neurobiology of Aging. 21: 150. DOI: 10.1016/S0197-4580(00)82475-6 |
0.653 |
|
| 2000 |
Iqdal K, Alonso AdC, Gong C, Khatoon S, Wang J, Grundke-Iqbal I. Mechanism of neurofibrillary degeneration Neurobiology of Aging. 21: 142. DOI: 10.1016/S0197-4580(00)82440-9 |
0.305 |
|
| 2000 |
Haque N, Zhong J, Iqbal K, Grundke-Iqbal I. Overexpression of tau associates with differentiation of neuronal cells in culture Neurobiology of Aging. 21: 110. DOI: 10.1016/S0197-4580(00)82291-5 |
0.502 |
|
| 2000 |
del C. Alonso A, Zaidi T, Grundke-Iqbal I, Iqbal K. In vitro self assembly of abnormally hyperphosphorylated tau into PHF-like structures Neurobiology of Aging. 21: 197. DOI: 10.1016/S0197-4580(00)82228-9 |
0.524 |
|
| 1999 |
Grundke-Iqbal I, Iqbal K. Tau pathology generated by overexpression of tau. The American Journal of Pathology. 155: 1781-5. PMID 10595905 DOI: 10.1016/S0002-9440(10)65494-6 |
0.613 |
|
| 1999 |
Pei JJ, Braak E, Braak H, Grundke-Iqbal I, Iqbal K, Winblad B, Cowburn RF. Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes. Journal of Neuropathology and Experimental Neurology. 58: 1010-9. PMID 10499443 DOI: 10.1097/00005072-199909000-00011 |
0.575 |
|
| 1999 |
Haque N, Tanaka T, Iqbal K, Grundke-Iqbal I. Regulation of expression, phosphorylation and biological activity of tau during differentiation in SY5Y cells. Brain Research. 838: 69-77. PMID 10446318 DOI: 10.1016/S0006-8993(99)01622-4 |
0.633 |
|
| 1999 |
Zhong J, Iqbal K, Grundke-Iqbal I. Hyperphosphorylated tau in SY5Y cells: similarities and dissimilarities to abnormally hyperphosphorylated tau from Alzheimer disease brain. Febs Letters. 453: 224-8. PMID 10403408 DOI: 10.1016/S0014-5793(99)00715-2 |
0.632 |
|
| 1999 |
Tatebayashi Y, Iqbal K, Grundke-Iqbal I. Dynamic regulation of expression and phosphorylation of tau by fibroblast growth factor-2 in neural progenitor cells from adult rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5245-54. PMID 10377336 DOI: 10.1523/Jneurosci.19-13-05245.1999 |
0.601 |
|
| 1998 |
Iqbal K, Grundke-Iqbal I. Tau phosphatase activity as a therapeutic target for AD. Drug News & Perspectives. 11: 10-4. PMID 15616638 |
0.638 |
|
| 1998 |
Sironi JJ, Yen SH, Gondal JA, Wu Q, Grundke-Iqbal I, Iqbal K. Ser-262 in human recombinant tau protein is a markedly more favorable site for phosphorylation by CaMKII than PKA or PhK. Febs Letters. 436: 471-5. PMID 9801171 DOI: 10.1016/S0014-5793(98)01185-5 |
0.644 |
|
| 1998 |
Wang JZ, Wu Q, Smith A, Grundke-Iqbal I, Iqbal K. Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase. Febs Letters. 436: 28-34. PMID 9771888 DOI: 10.1016/S0014-5793(98)01090-4 |
0.646 |
|
| 1998 |
Sengupta A, Kabat J, Novak M, Wu Q, Grundke-Iqbal I, Iqbal K. Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules. Archives of Biochemistry and Biophysics. 357: 299-309. PMID 9735171 DOI: 10.1006/Abbi.1998.0813 |
0.628 |
|
| 1998 |
Iqbal K, Alonso AC, Gong CX, Khatoon S, Pei JJ, Wang JZ, Grundke-Iqbal I. Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles. Journal of Neural Transmission. Supplementum. 53: 169-80. PMID 9700655 DOI: 10.1007/978-3-7091-6467-9_15 |
0.7 |
|
| 1998 |
Ikura Y, Kudo T, Tanaka T, Tanii H, Grundke-Iqbal I, Iqbal K, Takeda M. Levels of tau phosphorylation at different sites in Alzheimer disease brain. Neuroreport. 9: 2375-9. PMID 9694231 DOI: 10.1097/00001756-199807130-00041 |
0.667 |
|
| 1998 |
Pei JJ, Grundke-Iqbal I, Iqbal K, Bogdanovic N, Winblad B, Cowburn RF. Accumulation of cyclin-dependent kinase 5 (cdk5) in neurons with early stages of Alzheimer's disease neurofibrillary degeneration. Brain Research. 797: 267-77. PMID 9666145 DOI: 10.1016/S0006-8993(98)00296-0 |
0.614 |
|
| 1998 |
Tanaka T, Zhong J, Iqbal K, Trenkner E, Grundke-Iqbal I. The regulation of phosphorylation of tau in SY5Y neuroblastoma cells: the role of protein phosphatases. Febs Letters. 426: 248-54. PMID 9599018 DOI: 10.1016/S0014-5793(98)00346-9 |
0.633 |
|
| 1998 |
Pei JJ, Gong CX, Iqbal K, Grundke-Iqbal I, Wu QL, Winblad B, Cowburn RF. Subcellular distribution of protein phosphatases and abnormally phosphorylated tau in the temporal cortex from Alzheimer's disease and control brains. Journal of Neural Transmission (Vienna, Austria : 1996). 105: 69-83. PMID 9588762 DOI: 10.1007/S007020050039 |
0.675 |
|
| 1997 |
Pei JJ, Grundke-Iqbal I, Iqbal K, Bogdanovic N, Winblad B, Cowburn RF. Elevated protein levels of protein phosphatases PP-2A and PP-2B in astrocytes of Alzheimer's disease temporal cortex. Journal of Neural Transmission (Vienna, Austria : 1996). 104: 1329-38. PMID 9503279 DOI: 10.1007/Bf01294734 |
0.437 |
|
| 1997 |
Iqbal K, Grundke-Iqbal I. Elevated levels of tau and ubiquitin in brain and cerebrospinal fluid in Alzheimer's disease. International Psychogeriatrics / Ipa. 9: 289-96; discussion 3. PMID 9447449 DOI: 10.1017/S1041610297005024 |
0.653 |
|
| 1997 |
Ruben GC, Ciardelli TL, Grundke-Iqbal I, Iqbal K. Alzheimer disease hyperphosphorylated tau aggregates hydrophobically. Synapse (New York, N.Y.). 27: 208-29. PMID 9329157 DOI: 10.1002/(Sici)1098-2396(199711)27:3<208::Aid-Syn7>3.0.Co;2-H |
0.646 |
|
| 1997 |
Iqbal K, Grundke-Iqbal I. Mechanism of Alzheimer neurofibrillary degeneration and the formation of tangles. Molecular Psychiatry. 2: 178-80. PMID 9152977 |
0.381 |
|
| 1997 |
Singh TJ, Grundke-Iqbal I, Wu WQ, Chauhan V, Novak M, Kontzekova E, Iqbal K. Protein kinase C and calcium/calmodulin-dependent protein kinase II phosphorylate three-repeat and four-repeat tau isoforms at different rates. Molecular and Cellular Biochemistry. 168: 141-8. PMID 9062903 DOI: 10.1023/A:1006807105059 |
0.66 |
|
| 1997 |
Sengupta A, Wu Q, Grundke-Iqbal I, Iqbal K, Singh TJ. Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5. Molecular and Cellular Biochemistry. 167: 99-105. PMID 9059986 DOI: 10.1023/A:1006883924775 |
0.629 |
|
| 1997 |
Alonso AD, Grundke-Iqbal I, Barra HS, Iqbal K. Abnormal phosphorylation of tau and the mechanism of Alzheimer neurofibrillary degeneration: sequestration of microtubule-associated proteins 1 and 2 and the disassembly of microtubules by the abnormal tau. Proceedings of the National Academy of Sciences of the United States of America. 94: 298-303. PMID 8990203 DOI: 10.1073/Pnas.94.1.298 |
0.641 |
|
| 1997 |
Pei JJ, Tanaka T, Tung YC, Braak E, Iqbal K, Grundke-Iqbal I. Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain. Journal of Neuropathology and Experimental Neurology. 56: 70-8. PMID 8990130 DOI: 10.1097/00005072-199701000-00007 |
0.675 |
|
| 1996 |
Gong CX, Shaikh S, Grundke-Iqbal I, Iqbal K. Inhibition of protein phosphatase-2B (calcineurin) activity towards Alzheimer abnormally phosphorylated tau by neuroleptics. Brain Research. 741: 95-102. PMID 9001710 DOI: 10.1016/S0006-8993(96)00904-3 |
0.65 |
|
| 1996 |
Wang JZ, Grundke-Iqbal I, Iqbal K. Restoration of biological activity of Alzheimer abnormally phosphorylated tau by dephosphorylation with protein phosphatase-2A, -2B and -1. Brain Research. Molecular Brain Research. 38: 200-8. PMID 8793108 DOI: 10.1016/0169-328X(95)00316-K |
0.648 |
|
| 1996 |
Singh TJ, Zaidi T, Grundke-Iqbal I, Iqbal K. Non-proline-dependent protein kinases phosphorylate several sites found in tau from Alzheimer disease brain. Molecular and Cellular Biochemistry. 154: 143-51. PMID 8717428 DOI: 10.1007/Bf00226782 |
0.627 |
|
| 1996 |
Wang JZ, Grundke-Iqbal I, Iqbal K. Glycosylation of microtubule-associated protein tau: an abnormal posttranslational modification in Alzheimer's disease. Nature Medicine. 2: 871-5. PMID 8705855 DOI: 10.1038/Nm0896-871 |
0.696 |
|
| 1996 |
Singh TJ, Wang JZ, Novak M, Kontzekova E, Grundke-Iqbal I, Iqbal K. Calcium/calmodulin-dependent protein kinase II phosphorylates tau at Ser-262 but only partially inhibits its binding to microtubules. Febs Letters. 387: 145-8. PMID 8674537 DOI: 10.1016/0014-5793(96)00485-1 |
0.588 |
|
| 1996 |
Alonso AC, Grundke-Iqbal I, Iqbal K. Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules. Nature Medicine. 2: 783-7. PMID 8673924 DOI: 10.1038/Nm0796-783 |
0.584 |
|
| 1996 |
Singh TJ, Grundke-Iqbal I, Iqbal K. Differential phosphorylation of human tau isoforms containing three repeats by several protein kinases. Archives of Biochemistry and Biophysics. 328: 43-50. PMID 8638936 DOI: 10.1006/Abbi.1996.0140 |
0.657 |
|
| 1996 |
Iqbal K, Grundke-Iqbal I. Molecular mechanism of Alzheimer's neurofibrillary degeneration and therapeutic intervention. Annals of the New York Academy of Sciences. 777: 132-8. PMID 8624075 |
0.533 |
|
| 1996 |
Tanaka T, Iqbal K, Trenkner E, Grundke-Iqbal I. 621 The regulation of phosphorylation of Tau in SYSY neuroblastoma cells Neurobiology of Aging. 17: S154-S155. DOI: 10.1016/S0197-4580(96)80623-3 |
0.605 |
|
| 1996 |
Ikura Y, Kudo T, Grundke-Iqbal I, Iqbal K, Takeda M, Nishimura T. 536 Tau in Alzheimer disease brain is phosphorylated to different degrees at different sites Neurobiology of Aging. 17: S133-S134. DOI: 10.1016/S0197-4580(96)80538-0 |
0.644 |
|
| 1996 |
Sengupta A, Wu Q, Grundke-Iqbal I, Iqbal K, Singh T. 535 Potentiation of GSK-3-catalyzed Alzheimer-like phosphorylation of human tau by cdk5 Neurobiology of Aging. 17: S133. DOI: 10.1016/S0197-4580(96)80537-9 |
0.646 |
|
| 1996 |
Haque N, Tanaka T, Iqbal K, Grundke-Iqbal I. 532 Differentiation of SYSY cells: Effect on phosphorylation and biological activity of tau Neurobiology of Aging. 17: S132-S133. DOI: 10.1016/S0197-4580(96)80534-3 |
0.524 |
|
| 1996 |
Pei J, Tanaka T, Gong C, Braak E, Cowburn R, Winblad B, Iqbal K, Grundke-Iqbal I. 516 Expression of protein kinase GSK-3 and protein phosphatases PP-1, PP 2A, and PP-2B in the brain of patients with Alzheimer's disease Neurobiology of Aging. 17: S128-S129. DOI: 10.1016/S0197-4580(96)80518-5 |
0.528 |
|
| 1996 |
Kudo T, Takeda M, Miyamae Y, Morihara T, Kashiwagi Y, Tatebayashi Y, Nishimura T, Tanaka T, Iqbal K, Grundke-Iqbal I. 319 Alterations of presenilin I in fibroblasts from familial Alzheimer disease patients Neurobiology of Aging. 17: S80. DOI: 10.1016/S0197-4580(96)80321-6 |
0.512 |
|
| 1996 |
Singh T, Grundke-Iqbal I, Iqbal K. 168 Differential phosphorylation of three-repeat human tau isoforms by several protein kinases Neurobiology of Aging. 17: S43. DOI: 10.1016/S0197-4580(96)80170-9 |
0.592 |
|
| 1995 |
Wang JZ, Gong CX, Zaidi T, Grundke-Iqbal I, Iqbal K. Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B. The Journal of Biological Chemistry. 270: 4854-60. PMID 7876258 DOI: 10.1074/Jbc.270.9.4854 |
0.608 |
|
| 1995 |
Haque N, Denman RB, Merz G, Grundke-Iqbal I, Iqbal K. Phosphorylation and accumulation of tau without any concomitant increase in tubulin levels in Chinese hamster ovary cells stably transfected with human tau441. Febs Letters. 360: 132-6. PMID 7875317 DOI: 10.1016/0014-5793(95)00089-R |
0.601 |
|
| 1995 |
Tanaka T, Iqbal K, Trenkner E, Liu DJ, Grundke-Iqbal I. Abnormally phosphorylated tau in SY5Y human neuroblastoma cells. Febs Letters. 360: 5-9. PMID 7875300 DOI: 10.1016/0014-5793(95)00061-D |
0.668 |
|
| 1995 |
Khatoon S, Grundke-Iqbal I, Iqbal K. Guanosine triphosphate binding to beta-subunit of tubulin in Alzheimer's disease brain: role of microtubule-associated protein tau. Journal of Neurochemistry. 64: 777-87. PMID 7830071 DOI: 10.1046/j.1471-4159.1995.64020777.x |
0.592 |
|
| 1995 |
Singh TJ, Zaidi T, Grundke-Iqbal I, Iqbal K. Modulation of GSK-3-catalyzed phosphorylation of microtubule-associated protein tau by non-proline-dependent protein kinases. Febs Letters. 358: 4-8. PMID 7821426 DOI: 10.1016/0014-5793(94)01383-C |
0.592 |
|
| 1995 |
Gong CX, Shaikh S, Wang JZ, Zaidi T, Grundke-Iqbal I, Iqbal K. Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain. Journal of Neurochemistry. 65: 732-8. PMID 7616230 |
0.523 |
|
| 1995 |
Singh TJ, Grundke-Iqbal I, Iqbal K. Phosphorylation of tau protein by casein kinase-1 converts it to an abnormal Alzheimer-like state. Journal of Neurochemistry. 64: 1420-3. PMID 7532213 |
0.416 |
|
| 1995 |
Singh TJ, Haque N, Grundke-Iqbal I, Iqbal K. Rapid Alzheimer-like phosphorylation of tau by the synergistic actions of non-proline-dependent protein kinases and GSK-3. Febs Letters. 358: 267-72. PMID 7531159 DOI: 10.1016/0014-5793(94)01445-7 |
0.674 |
|
| 1995 |
Alonso Adel C, Grundke-Iqbal I, Iqbal K. Bovine and human tau, highly homologous but less crossreactive: implications for Alzheimer disease. Brain Research. Molecular Brain Research. 31: 194-200. PMID 7476029 DOI: 10.1016/0169-328X(95)00051-S |
0.615 |
|
| 1995 |
Iqbal K, Grundke-Iqbal I. Alzheimer abnormally phosphorylated tau is more hyperphosphorylated than the fetal tau and causes the disruption of microtubules Neurobiology of Aging. 16: 375-379. DOI: 10.1016/0197-4580(95)00033-B |
0.672 |
|
| 1995 |
Iqbal K, Grundke-Iqbal I. Abnormal hyperphosphorylation of tau: Participation of β-amyloid/peptide out and proline-directed protein kinases (PDPKs) and non-PDPKs in Neurobiology of Aging. 16: 398. DOI: 10.1016/0197-4580(94)00161-S |
0.569 |
|
| 1994 |
Gong CX, Singh TJ, Grundke-Iqbal I, Iqbal K. Alzheimer's disease abnormally phosphorylated tau is dephosphorylated by protein phosphatase-2B (calcineurin). Journal of Neurochemistry. 62: 803-6. PMID 8294942 |
0.507 |
|
| 1994 |
Alonso AC, Zaidi T, Grundke-Iqbal I, Iqbal K. Role of abnormally phosphorylated tau in the breakdown of microtubules in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 5562-6. PMID 8202528 DOI: 10.1073/Pnas.91.12.5562 |
0.607 |
|
| 1994 |
Kudo T, Iqbal K, Ravid R, Swaab DF, Grundke-Iqbal I. Alzheimer disease: correlation of cerebro-spinal fluid and brain ubiquitin levels. Brain Research. 639: 1-7. PMID 8180825 DOI: 10.1016/0006-8993(94)91757-4 |
0.581 |
|
| 1994 |
Gong CX, Grundke-Iqbal I, Damuni Z, Iqbal K. Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease. Febs Letters. 341: 94-8. PMID 8137929 DOI: 10.1016/0014-5793(94)80247-5 |
0.662 |
|
| 1994 |
Khatoon S, Grundke-Iqbal I, Iqbal K. Levels of normal and abnormally phosphorylated tau in different cellular and regional compartments of Alzheimer disease and control brains. Febs Letters. 351: 80-4. PMID 8076698 DOI: 10.1016/0014-5793(94)00829-9 |
0.669 |
|
| 1994 |
Rehman A, Tung YC, Iqbal K, Grundke-Iqbal I. Rabbit IgG cross-reacts with Alzheimer neurofibrillary tangles. Acta Neuropathologica. 87: 443-9. PMID 8059596 DOI: 10.1007/Bf00294170 |
0.645 |
|
| 1994 |
Iqbal K, Zaidi T, Bancher C, Grundke-Iqbal I. Alzheimer paired helical filaments. Restoration of the biological activity by dephosphorylation. Febs Letters. 349: 104-8. PMID 8045285 DOI: 10.1016/0014-5793(94)00650-4 |
0.684 |
|
| 1994 |
Singh TJ, Grundke-Iqbal I, McDonald B, Iqbal K. Comparison of the phosphorylation of microtubule-associated protein tau by non-proline dependent protein kinases. Molecular and Cellular Biochemistry. 131: 181-9. PMID 8035784 DOI: 10.1007/Bf00925955 |
0.583 |
|
| 1994 |
Kudo T, Iqbal K, Ravid R, Swaab DF, Grundke-Iqbal I. Ubiquitin in cerebrospinal fluid: a rapid competitive enzyme-linked immunoflow assay. Neuroreport. 5: 1522-4. PMID 7948853 DOI: 10.1097/00001756-199407000-00028 |
0.417 |
|
| 1994 |
Iqbal K, Alonso AC, Gong CX, Khatoon S, Singh TJ, Grundke-Iqbal I. Mechanism of neurofibrillary degeneration in Alzheimer's disease. Molecular Neurobiology. 9: 119-23. PMID 7888088 DOI: 10.1007/Bf02816111 |
0.711 |
|
| 1994 |
Gong CX, Grundke-Iqbal I, Iqbal K. Dephosphorylation of Alzheimer's disease abnormally phosphorylated tau by protein phosphatase-2A. Neuroscience. 61: 765-72. PMID 7838376 DOI: 10.1016/0306-4522(94)90400-6 |
0.447 |
|
| 1994 |
Pei JJ, Sersen E, Iqbal K, Grundke-Iqbal I. Expression of protein phosphatases (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals. Brain Research. 655: 70-6. PMID 7812792 DOI: 10.1016/0006-8993(94)91598-9 |
0.618 |
|
| 1993 |
Gong CX, Singh TJ, Grundke-Iqbal I, Iqbal K. Phosphoprotein phosphatase activities in Alzheimer disease brain. Journal of Neurochemistry. 61: 921-7. PMID 8395566 DOI: 10.1111/J.1471-4159.1993.Tb03603.X |
0.59 |
|
| 1993 |
Iqbal K, Alonso A, Gong C, Khatoon S, Kudo T, Singh T, Grundke-Iqbal I. Molecular pathology of Alzheimer neurofibrillary degeneration. Acta Neurobiologiae Experimentalis. 53: 325-35. PMID 8317268 |
0.53 |
|
| 1993 |
Köpke E, Tung YC, Shaikh S, Alonso AC, Iqbal K, Grundke-Iqbal I. Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. The Journal of Biological Chemistry. 268: 24374-84. PMID 8226987 |
0.516 |
|
| 1993 |
Ruben GC, Iqbal K, Wisniewski HM, Johnson JE, Grundke-Iqbal I. Alzheimer neurofibrillary tangles contain 2.1 nm filaments structurally identical to the microtubule-associated protein tau: a high-resolution transmission electron microscope study of tangles and senile plaque core amyloid. Brain Research. 602: 164-79. PMID 7680597 DOI: 10.1016/0006-8993(92)91092-S |
0.562 |
|
| 1993 |
Iqbal K, Braak H, Braak E, Grundke-Iqbal I. Silver labeling of Alzheimer neurofibrillary changes and brain β-amyloid Journal of Histotechnology. 16: 335-341. DOI: 10.1179/His.1993.16.4.335 |
0.521 |
|
| 1993 |
Iqbal K, Gong CX, Singh TJ, Grundke-Iqbal I. ABNORMALLY PHOSPHORYLATED TAU IN ALZHEIMER DISEASE BRAIN Journal of Neuropathology and Experimental Neurology. 52: 266. DOI: 10.1097/00005072-199305000-00023 |
0.674 |
|
| 1993 |
Ruben GC, Iqbal K, Wisniewski HM, Johnson JE, Grundke-Iqbal I. Alzheimer neurofibrillary tangles contain 2.1 nm filaments structurally identical to the microtubule-associated protein τ: a high-resolution transmission electron microscope study of tangles and senile plaque core amyloid Brain Research. 602: E1-E18. DOI: 10.1016/0006-8993(92)91092-S |
0.343 |
|
| 1992 |
Khatoon S, Grundke-Iqbal I, Iqbal K. Brain levels of microtubule-associated protein tau are elevated in Alzheimer's disease: a radioimmuno-slot-blot assay for nanograms of the protein. Journal of Neurochemistry. 59: 750-3. PMID 1629745 |
0.532 |
|
| 1992 |
Lin FH, Lin R, Wisniewski HM, Hwang YW, Grundke-Iqbal I, Healy-Louie G, Iqbal K. Detection of point mutations in codon 331 of mitochondrial NADH dehydrogenase subunit 2 in Alzheimer's brains. Biochemical and Biophysical Research Communications. 182: 238-46. PMID 1370613 DOI: 10.1016/S0006-291X(05)80136-6 |
0.52 |
|
| 1992 |
Swaab DF, Grundke-Iqbal I, Iqbal K, Kremer HP, Ravid R, van de Nes JA. Tau and ubiquitin in the human hypothalamus in aging and Alzheimer's disease. Brain Research. 590: 239-49. PMID 1330213 DOI: 10.1016/0006-8993(92)91101-J |
0.636 |
|
| 1992 |
Swaab D, Grundke-Iqbal I, Iqbal K, Lucassen P, Raadsheer F, Ravid R, Van de Nes J. The human hypothalamus and Alzheimer symptoms Neurobiology of Aging. 13: S44. DOI: 10.1016/0197-4580(92)90299-D |
0.468 |
|
| 1991 |
Ruben GC, Iqbal K, Grundke-Iqbal I, Wisniewski HM, Ciardelli TL, Johnson JE. The microtubule-associated protein tau forms a triple-stranded left-hand helical polymer. The Journal of Biological Chemistry. 266: 22019-27. PMID 1939223 |
0.394 |
|
| 1991 |
Bancher C, Grundke-Iqbal I, Iqbal K, Fried VA, Smith HT, Wisniewski HM. Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease. Brain Research. 539: 11-8. PMID 1849776 DOI: 10.1016/0006-8993(91)90681-K |
0.44 |
|
| 1991 |
Wang GP, Khatoon S, Iqbal K, Grundke-Iqbal I. Brain ubiquitin is markedly elevated in Alzheimer disease. Brain Research. 566: 146-51. PMID 1814531 DOI: 10.1016/0006-8993(91)91692-T |
0.623 |
|
| 1991 |
Iqbal K, Grundke-Iqbal I. Ubiquitination and abnormal phosphorylation of paired helical filaments in Alzheimer's disease. Molecular Neurobiology. 5: 399-410. PMID 1726645 DOI: 10.1007/Bf02935561 |
0.69 |
|
| 1991 |
Iqbal K, Braak E, Braak H, Zaidi T, Grundke-Iqbal I. A silver impregnation method for labeling both Alzheimer paired helical filaments and their polypeptides separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Neurobiology of Aging. 12: 357-61. PMID 1720514 DOI: 10.1016/0197-4580(91)90022-C |
0.597 |
|
| 1991 |
Wang GP, Iqbal K, Bucht G, Winblad B, Wisniewski HM, Grundke-Iqbal I. Alzheimer's disease: paired helical filament immunoreactivity in cerebrospinal fluid. Acta Neuropathologica. 82: 6-12. PMID 1659107 DOI: 10.1007/Bf00310917 |
0.51 |
|
| 1991 |
Wisniewski HM, Dymecki J, Wegiel J, Kulczycki J, Schmidt-Sidor B, Grundke-Iqbal I, Strojny P. Neurofibrillary Pathology in Subacute Sclerosing Panencephalitis Dementia and Geriatric Cognitive Disorders. 2: 133-141. DOI: 10.1159/000107188 |
0.501 |
|
| 1990 |
Grundke-Iqbal I, Fleming J, Tung YC, Lassmann H, Iqbal K, Joshi JG. Ferritin is a component of the neuritic (senile) plaque in Alzheimer dementia. Acta Neuropathologica. 81: 105-10. PMID 2082650 DOI: 10.1007/Bf00334497 |
0.531 |
|
| 1989 |
Grundke-Iqbal I, Iqbal K. Neuronal cytoskeleton in the biology of Alzheimer disease. Progress in Clinical and Biological Research. 317: 745-53. PMID 2690119 |
0.445 |
|
| 1989 |
Iqbal K, Wang GP, Grundke-Iqbal I, Wisniewski HM. Laboratory diagnostic tests for Alzheimer's disease. Progress in Clinical and Biological Research. 317: 679-87. PMID 2690116 |
0.371 |
|
| 1989 |
Barcikowska M, Wisniewski HM, Bancher C, Grundke-Iqbal I. About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation. Acta Neuropathologica. 78: 225-31. PMID 2669434 DOI: 10.1007/Bf00687751 |
0.364 |
|
| 1989 |
Bancher C, Grundke-Iqbal I, Iqbal K, Kim KS, Wisniewski HM. Immunoreactivity of neuronal lipofuscin with monoclonal antibodies to the amyloid beta-protein. Neurobiology of Aging. 10: 125-32. PMID 2657463 DOI: 10.1016/0197-4580(89)90021-3 |
0.51 |
|
| 1989 |
Grundke-Iqbal I, Iqbal K, George L, Tung YC, Kim KS, Wisniewski HM. Amyloid protein and neurofibrillary tangles coexist in the same neuron in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 86: 2853-7. PMID 2649895 DOI: 10.1073/Pnas.86.8.2853 |
0.549 |
|
| 1989 |
Bancher C, Brunner C, Lassmann H, Budka H, Jellinger K, Seitelberger F, Grundke-Iqbal I, Iqbal K, Wisniewski HM. Tau and ubiquitin immunoreactivity at different stages of formation of Alzheimer neurofibrillary tangles. Progress in Clinical and Biological Research. 317: 837-48. PMID 2557644 |
0.405 |
|
| 1989 |
Iqbal K, Grundke-Iqbal I, Smith AJ, George L, Tung YC, Zaidi T. Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 86: 5646-50. PMID 2501795 DOI: 10.1073/Pnas.86.14.5646 |
0.57 |
|
| 1989 |
Iqbal K, Smith AJ, Zaidi T, Grundke-Iqbal I. Microtubule-associated protein tau. Identification of a novel peptide from bovine brain. Febs Letters. 248: 87-91. PMID 2498127 DOI: 10.1016/0014-5793(89)80437-5 |
0.553 |
|
| 1989 |
Bancher C, Brunner C, Lassmann H, Budka H, Jellinger K, Wiche G, Seitelberger F, Grundke-Iqbal I, Iqbal K, Wisniewski HM. Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease. Brain Research. 477: 90-9. PMID 2495152 DOI: 10.1016/0006-8993(89)91396-6 |
0.502 |
|
| 1989 |
Shankar SK, Yanagihara R, Garruto RM, Grundke-Iqbal I, Kosik KS, Gajdusek DC. Immunocytochemical characterization of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia of Guam. Annals of Neurology. 25: 146-51. PMID 2493213 DOI: 10.1002/ana.410250207 |
0.31 |
|
| 1989 |
Perry G, Mulvihill P, Fried VA, Smith HT, Grundke-Iqbal I, Iqbal K. Immunochemical properties of ubiquitin conjugates in the paired helical filaments of Alzheimer disease. Journal of Neurochemistry. 52: 1523-8. PMID 2468737 DOI: 10.1111/J.1471-4159.1989.Tb09203.X |
0.496 |
|
| 1989 |
Bancher C, Lassmann H, Budka H, Jellinger K, Grundke-Iqbal I, Iqbal K, Wiche G, Seitelberger F, Wisniewski HM. An antigenic profile of Lewy bodies: immunocytochemical indication for protein phosphorylation and ubiquitination. Journal of Neuropathology and Experimental Neurology. 48: 81-93. PMID 2462024 DOI: 10.1097/00005072-198901000-00007 |
0.517 |
|
| 1989 |
Iqbal K, Grundke-Iqbal I, Smith. A. MICROTUBULE ASSOCIATED PROTEIN TAU Journal of Neuropathology and Experimental Neurology. 48: 353. DOI: 10.1097/00005072-198905000-00164 |
0.595 |
|
| 1989 |
Bancher C, Grundke-Iqbal I, Iqbal K, Kim KS, Wisniewski HM. A FRAGMENT OF THE AMYLOID PRECURSOR PROTEIN IN NEURONAL LIPOFUSCIN? Journal of Neuropathology and Experimental Neurology. 48: 332. DOI: 10.1097/00005072-198905000-00100 |
0.508 |
|
| 1988 |
Grundke-Iqbal I, Vorbrodt AW, Iqbal K, Tung YC, Wang GP, Wisniewski HM. Microtubule-associated polypeptides tau are altered in Alzheimer paired helical filaments. Brain Research. 464: 43-52. PMID 3141008 DOI: 10.1016/0169-328X(88)90017-4 |
0.634 |
|
| 1988 |
Galloway PG, Grundke-Iqbal I, Iqbal K, Perry G. Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles. Journal of Neuropathology and Experimental Neurology. 47: 654-63. PMID 2459316 DOI: 10.1097/00005072-198811000-00008 |
0.599 |
|
| 1988 |
BANCHER C, BRUNNER C, LASSMANN H, BUDKA H, JELLINGER K, SEITELBERGER F, GRUNDKE-IQBAL I, IQBAL K, WISNIEWSKI HM. TAU AND UBIQUITIN IMMUNOREACTIVITY AT DIFFERENT STAGES OF FORMATION OF ALZHEIMER NEUROFIBRILLARY TANGLES Alzheimer Disease & Associated Disorders. 2: 202. DOI: 10.1097/00002093-198802030-00051 |
0.616 |
|
| 1988 |
WANG GP, GRUNDKE-IQBAL I, IQBAL K. QUANTITATION OF MICROTOBULE ASSOCIATED PROTEIN TAU IN PAIRED HELICAL FILAMENTS BY IMMUNOASSAY Alzheimer Disease & Associated Disorders. 2: 201. DOI: 10.1097/00002093-198802030-00050 |
0.591 |
|
| 1988 |
IQBAL K, WANG GP, WISNIEWSKI HH, GRUNDKE-IQBAL I. PAIRED HELICAL FILAMENT (PHF) IMMUNOREACTIVITY IN CSF Alzheimer Disease & Associated Disorders. 2: 175. DOI: 10.1097/00002093-198802030-00024 |
0.459 |
|
| 1987 |
Popovitch ER, Wisniewski HM, Kaufman MA, Grundke-Iqbal I, Wen GY. Young adult-form of dementia with neurofibrillary changes and Lewy bodies. Acta Neuropathologica. 74: 97-104. PMID 3661124 DOI: 10.1007/Bf00688346 |
0.353 |
|
| 1987 |
Wisniewski HM, Iqbal K, Grundke-Iqbal I, Rubenstein R. The solubility controversy of paired helical filaments: a commentary. Neurochemical Research. 12: 93-5. PMID 3574590 DOI: 10.1007/Bf00971370 |
0.406 |
|
| 1987 |
Alafuzoff I, Adolfsson R, Grundke-Iqbal I, Winblad B. Blood-brain barrier in Alzheimer dementia and in non-demented elderly. An immunocytochemical study. Acta Neuropathologica. 73: 160-6. PMID 3300132 DOI: 10.1007/Bf00693782 |
0.465 |
|
| 1987 |
Iqbal K, Grundke-Iqbal I, Merz PA, Wisniewski HM, Zaidi T. In vitro assembly and isolation of neurofilaments and microtubules from mammalian CNS. Brain Research. 388: 163-72. PMID 3113660 DOI: 10.1016/0169-328X(87)90010-6 |
0.497 |
|
| 1987 |
Bancher C, Lassmann H, Budka H, Grundke-Iqbal I, Iqbal K, Wiche G, Seitelberger F, Wisniewski HM. Neurofibrillary tangles in Alzheimer's disease and progressive supranuclear palsy: antigenic similarities and differences. Microtubule-associated protein tau antigenicity is prominent in all types of tangles. Acta Neuropathologica. 74: 39-46. PMID 2444063 DOI: 10.1007/Bf00688336 |
0.585 |
|
| 1987 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM. Alzheimer's disease, microtubule and neurofilament proteins, and axoplasmic flow. Lancet. 1: 102. PMID 2432366 DOI: 10.1016/S0140-6736(87)91937-4 |
0.557 |
|
| 1987 |
Grundke-Iqbal I, Iqbal K, Wang GP, Wisniewaki HM. MICROTUBULE ASSOCIATED PROTEIN TAU IN ALZHEIMER PAIRED HELICAL FILAMENTS (PHF) Journal of Neuropathology and Experimental Neurology. 46: 376. DOI: 10.1097/00005072-198705000-00141 |
0.644 |
|
| 1987 |
Merz PA, Wrzolek M, Kascsak RJ, Grundke-Iqbal I, Iqbal K, Binder L, Kosik K, Wisniewski HM. IMMUNE ELECTRON MICROSCOPY OF PAIRED HELICAL FILAMENTS (PHF) WITH TAU ANTIBODIES Journal of Neuropathology and Experimental Neurology. 46: 376. DOI: 10.1097/00005072-198705000-00139 |
0.51 |
|
| 1987 |
WRZOLEK M, MERZ PA, KASCSAK RJ, GRUNDKE-IQBAL I, IQBAL K, RUBENSTEIN R, WISNIEWSKI HM, Lossinsky A. IMMUNE ELECTRON MICROSCOPY OF MONOCLONAL ANTIBODIES TO ALZHEIMER NEUROFIBRILLARY TANGLES Journal of Neuropathology and Experimental Neurology. 46: 333. DOI: 10.1097/00005072-198705000-00012 |
0.496 |
|
| 1987 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM. A SILVER IMPREGNATION METHOD SPECIFIC FOR ALZHEIMER PAIRED HELICAL FILAMENTS (PHF) STAINS MICROTUBULE ASSOCIATED PROTEIN TAU. Journal of Neuropathology and Experimental Neurology. 46: 333. DOI: 10.1097/00005072-198705000-00011 |
0.636 |
|
| 1986 |
Iqbal K, Grundke-Iqbal I, Zaidi T, Ali N, Wisniewski HM. Are Alzheimer neurofibrillary tangles insoluble polymers? Life Sciences. 38: 1695-700. PMID 3702598 DOI: 10.1016/0024-3205(86)90414-5 |
0.528 |
|
| 1986 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM. Neuronal cytoskeleton in aging and dementia. Progress in Brain Research. 70: 279-88. PMID 3554352 |
0.387 |
|
| 1986 |
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI. Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proceedings of the National Academy of Sciences of the United States of America. 83: 4913-7. PMID 3088567 DOI: 10.1073/Pnas.83.13.4913 |
0.634 |
|
| 1986 |
Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi MS, Wisniewski HM. Microtubule-associated protein tau. A component of Alzheimer paired helical filaments. The Journal of Biological Chemistry. 261: 6084-9. PMID 3084478 |
0.424 |
|
| 1986 |
Iqbal K, Grundke-Iqbal I, Zaidi T, Merz PA, Wen GY, Shaikh SS, Wisniewski HM, Alafuzoff I, Winblad B. Defective brain microtubule assembly in Alzheimer's disease. Lancet. 2: 421-6. PMID 2874414 DOI: 10.1016/S0140-6736(86)92134-3 |
0.653 |
|
| 1986 |
Braak H, Braak E, Grundke-Iqbal I, Iqbal K. Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques. Neuroscience Letters. 65: 351-5. PMID 2423928 DOI: 10.1016/0304-3940(86)90288-0 |
0.581 |
|
| 1986 |
Grundke-Iqbal I, Iqbal K, Wisniewski HM. MICROTUBLE ASSOCIATED PROTEIN, TAU IS ABNORMALLY PHOSPHORYLATED IN ALZHEIMER BRAIN Journal of Neuropathology and Experimental Neurology. 45: 379. DOI: 10.1097/00005072-198605000-00194 |
0.674 |
|
| 1986 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM. MICROTUBULE ASSOCIATED PROTEIN, TAU IS A MAJOR CONSTITUENT OF ALZHEIMER PAIRED HELICAL FILAMENTS Journal of Neuropathology and Experimental Neurology. 45: 378. DOI: 10.1097/00005072-198605000-00193 |
0.642 |
|
| 1986 |
Merz PA, Grundke-Iqbal I, Iqbal K, Rubenstein R, Wisniewski, Rudelli RD. Immune Electron Microscopy Of Alzheimer Paired Helical Filaments (Phf) Journal of Neuropathology and Experimental Neurology. 45: 338. DOI: 10.1097/00005072-198605000-00076 |
0.504 |
|
| 1985 |
Alafuzoff I, Adolfsson R, Grundke-Iqbal I, Winblad B. Perivascular deposits of serum proteins in cerebral cortex in vascular dementia. Acta Neuropathologica. 66: 292-98. PMID 3893019 DOI: 10.1007/Bf00690961 |
0.359 |
|
| 1985 |
Grundke-Iqbal I, Iqbal K, Tung YC, Wang GP, Wisniewski HM. Alzheimer paired helical filaments: cross-reacting polypeptide/s normally present in brain. Acta Neuropathologica. 66: 52-61. PMID 2581415 DOI: 10.1007/Bf00698295 |
0.544 |
|
| 1985 |
Grundke-Iqbal I, Wang GP, Iqbal K, Tung YC, Wisniewski HM. Alzheimer paired helical filaments: identification of polypeptides with monoclonal antibodies. Acta Neuropathologica. 68: 279-83. PMID 2418620 DOI: 10.1007/Bf00690830 |
0.513 |
|
| 1984 |
Wang GP, Grundke-Iqbal I, Kascsak RJ, Iqbal K, Wisniewski HM. Alzheimer neurofibrillary tangles: monoclonal antibodies to inherent antigen(s). Acta Neuropathologica. 62: 268-75. PMID 6730905 DOI: 10.1007/Bf00687608 |
0.451 |
|
| 1984 |
Grundke-Iqbal I, Iqbal K, Tung YC, Wisniewski HM. Alzheimer paired helical filaments: immunochemical identification of polypeptides. Acta Neuropathologica. 62: 259-67. PMID 6428153 DOI: 10.1007/Bf00687607 |
0.491 |
|
| 1984 |
Grundke-Iqbal I, Iqbal K, Tung YC, Wang GP, Wisniewski HM. 163 ARE ALZHEIMER PAIRED HELICAL FILAMENT POLYPEPTIDES PRESENT NORMALLY IN BRAIN? Journal of Neuropathology and Experimental Neurology. 43: 347. DOI: 10.1097/00005072-198405000-00169 |
0.599 |
|
| 1984 |
Wang GP, Grundke-Iqbal I, Iqbal K, Wisniewski HM. 159 IDENTIFICATION OF ALZHEIMER PAIRED HELICAL FILAMENT POLYPEPTIDES WITH MONOCLONAL ANTIBODIES Journal of Neuropathology and Experimental Neurology. 43: 346. DOI: 10.1097/00005072-198405000-00165 |
0.535 |
|
| 1983 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM. 110 SOLUBILITY AND PROTEIN COMPOSITION OF ALZHEIMER NEUROFIBRILLARY TANGLES Journal of Neuropathology and Experimental Neurology. 42: 341. DOI: 10.1097/00005072-198305000-00117 |
0.582 |
|
| 1983 |
Grundke-Iqbal I, Wang GP, Iqbal K, Kascsak R, Wisniewski HM. 109 RELATIONSHIP OF ALZHEIMER PAIRED HELICAL FILAMENTS WITH MICROTUBULES AND NEUROFILAMENTS Journal of Neuropathology and Experimental Neurology. 42: 341. DOI: 10.1097/00005072-198305000-00116 |
0.592 |
|
| 1982 |
Iqbal K, Grundke-Iqbal I, Merz PA, Wisniewski HM. Alzheimer Neurofibrillary tangle: morphology and biochemistry. Experimental Brain Research. 10-4. PMID 7151901 |
0.579 |
|
| 1982 |
Wisniewski HM, Vorbrodt AW, Moretz RC, Lossinsky AS, Grundke-Iqbal I. Pathogenesis of neuritic (senile) and amyloid plaque formation. Experimental Brain Research. 3-9. PMID 6891336 |
0.305 |
|
| 1982 |
Grundke-Iqbal I, Iqbal K, Wisniewski HM. Immunocytochemical studies on neurofibrillary changes. Experimental Brain Research. 20-5. PMID 6185357 |
0.352 |
|
| 1981 |
Iqbal K, Merz V, Grundke-Iqbal I, Wisnlewski HM. 49 STUDIES ON MAMMALIAN NEUROFILAMENTS ISOLATED BY IN VITRO ASSEMBLY-DISASSEMBLY Journal of Neuropathology and Experimental Neurology. 40: 315. DOI: 10.1097/00005072-198105000-00056 |
0.344 |
|
| 1981 |
Grundke-Iqbal I, Iqbal K, Merz P, Wisniewski HM. 40 ISOLATION AND PROPERTIES OF ALZHEIMER NEUROFIBRILLARY TANGLES Journal of Neuropathology and Experimental Neurology. 40: 312. DOI: 10.1097/00005072-198105000-00047 |
0.554 |
|
| 1980 |
Iqbal K, Johnson AB, Grundke-Iqbal I, Wisniewski HM. 79 STUDIES ON ALZHEIMER NEUROFIBRILLARY TANGLE CROSS-REACTING ANTIGEN/S Journal of Neuropathology and Experimental Neurology. 39: 363. DOI: 10.1097/00005072-198005000-00087 |
0.54 |
|
| 1979 |
Grundke-Iqbal I, Johnson AB, Terry RD, Wisniewski HM, Iqbal K. Alzheimer neurofibrillary tangles: antiserum and immunohistological staining. Annals of Neurology. 6: 532-7. PMID 394670 DOI: 10.1002/Ana.410060612 |
0.589 |
|
| 1979 |
Grundke-Iqbal I, Johnson AB, Wisniewski HM, Terry RD, Iqbal K. Evidence that Alzheimer neurofibrillary tangles originate from neurotubules. Lancet (London, England). 1: 578-80. PMID 85165 DOI: 10.1016/S0140-6736(79)91006-7 |
0.372 |
|
| 1979 |
Iqbal K, Grundke-Iqbal I, Johnson AB, Wisniewski HM. ARE NEUROTUBULE PROTEINS INVOLVED IN THE FORMATION OF ALZHEIMER NEUROFIBRILLARY TANGLES? Journal of Neuropathology and Experimental Neurology. 38: 322. DOI: 10.1097/00005072-197905000-00074 |
0.612 |
|
| 1978 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM, Terry RD. Chemical relationship of the paired helical filaments of Alzheimer's dementia to normal human neurofilaments and neurotubules. Brain Research. 142: 321-32. PMID 630387 DOI: 10.1016/0006-8993(78)90638-8 |
0.523 |
|
| 1977 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM, Terry RD. On neurofilament and neurotubule proteins from human autopsy tissue. Journal of Neurochemistry. 29: 417-24. PMID 894298 DOI: 10.1111/J.1471-4159.1977.Tb10689.X |
0.392 |
|
| 1977 |
Iqbal K, Grundke-Iqbal I, Wisniewski HM. Oligodendroglia from human autopsied brain: bulk isolation and some chemical properties. Journal of Neurochemistry. 28: 707-16. PMID 894279 DOI: 10.1111/J.1471-4159.1977.Tb10617.X |
0.354 |
|
| 1975 |
Iqbal K, Wisniewski HM, Grundke-Iqbal I, Korthals JK, Terry RD. Chemical pathology of neurofibrils. Neurofibrillary tangles of Alzheimer's presenile-senile dementia. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 23: 563-9. PMID 1141687 DOI: 10.1177/23.7.1141687 |
0.541 |
|
| 1974 |
Iqbal K, Tellez-Nagel I, Grundke-Iqbal I. Protein abnormalities in Huntington's chorea. Brain Research. 76: 178-84. PMID 4276706 DOI: 10.1016/0006-8993(74)90527-7 |
0.404 |
|
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