| Year |
Citation |
Score |
| 2023 |
Neumann A, Ohlei O, Küçükali F, Bos IJ, Timsina J, Vos S, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Scheltens P, Teunissen CE, Engelborghs S, Frisoni GB, ... ... Lovestone S, et al. Multivariate GWAS of Alzheimer's disease CSF biomarker profiles implies GRIN2D in synaptic functioning. Genome Medicine. 15: 79. PMID 37794492 DOI: 10.1186/s13073-023-01233-z |
0.372 |
|
| 2023 |
Shi L, Xu J, Green R, Wretlind A, Homann J, Buckley NJ, Tijms BM, Vos SJB, Lill CM, Kate MT, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lleó A, ... ... Lovestone S, et al. Multiomics profiling of human plasma and cerebrospinal fluid reveals ATN-derived networks and highlights causal links in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36790009 DOI: 10.1002/alz.12961 |
0.4 |
|
| 2023 |
Maruszak A, Silajdžić E, Lee H, Murphy T, Liu B, Shi L, de Lucia C, Douiri A, Salta E, Nevado AJ, Teunissen CE, Visser PJ, Price J, Zetterberg H, Lovestone S, et al. Predicting progression to Alzheimer's disease with human hippocampal progenitors exposed to serum. Brain : a Journal of Neurology. PMID 36703180 DOI: 10.1093/brain/awac472 |
0.344 |
|
| 2022 |
Küçükali F, Neumann A, Van Dongen J, De Pooter T, Joris G, De Rijk P, Ohlei O, Dobricic V, Bos I, Vos SJB, Engelborghs S, De Roeck E, Vandenberghe R, Gabel S, Meersmans K, ... ... Lovestone S, et al. Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36464806 DOI: 10.1002/alz.12842 |
0.382 |
|
| 2022 |
Ng B, Rowland HA, Wei T, Arunasalam K, Hayes EM, Koychev I, Hedegaard A, Ribe EM, Chan D, Chessell T, Ffytche D, Gunn RN, Kocagoncu E, Lawson J, Malhotra PA, ... ... Lovestone S, et al. Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability. Brain Communications. 4: fcac267. PMID 36349119 DOI: 10.1093/braincomms/fcac267 |
0.321 |
|
| 2022 |
Foster EM, Fernandes M, Dangla-Valls A, Hublitz P, Pangalos M, Lovestone S, Ribe EM, Buckley NJ. Glycosylated clusterin species facilitate Aβ toxicity in human neurons. Scientific Reports. 12: 18639. PMID 36329114 DOI: 10.1038/s41598-022-23167-z |
0.301 |
|
| 2022 |
Delvenne A, Gobom J, Tijms B, Bos I, Reus LM, Dobricic V, Kate MT, Verhey F, Ramakers I, Scheltens P, Teunissen CE, Vandenberghe R, Schaeverbeke J, Gabel S, Popp J, ... ... Lovestone S, et al. Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non-Alzheimer's disease pathophysiology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35698882 DOI: 10.1002/alz.12713 |
0.319 |
|
| 2022 |
Wesenhagen KEJ, Gobom J, Bos I, Vos SJB, Martinez-Lage P, Popp J, Tsolaki M, Vandenberghe R, Freund-Levi Y, Verhey F, Lovestone S, Streffer J, Dobricic V, Bertram L, Blennow K, et al. Effects of age, amyloid, sex, and ε4 on the CSF proteome in normal cognition. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12286. PMID 35571963 DOI: 10.1002/dad2.12286 |
0.31 |
|
| 2022 |
Visser PJ, Reus LM, Gobom J, Jansen I, Dicks E, van der Lee SJ, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuevo JL, Engelborghs S, Freund-Levi Y, ... ... Lovestone S, et al. Correction: Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. Molecular Neurodegeneration. 17: 37. PMID 35550177 DOI: 10.1186/s13024-022-00540-0 |
0.307 |
|
| 2022 |
Hillary RF, Gadd DA, McCartney DL, Shi L, Campbell A, Walker RM, Ritchie CW, Deary IJ, Evans KL, Nevado-Holgado AJ, Hayward C, Porteous DJ, McIntosh AM, Lovestone S, Robinson MR, et al. Genome- and epigenome-wide studies of plasma protein biomarkers for Alzheimer's disease implicate TBCA and TREM2 in disease risk. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12280. PMID 35475137 DOI: 10.1002/dad2.12280 |
0.342 |
|
| 2022 |
Homann J, Osburg T, Ohlei O, Dobricic V, Deecke L, Bos I, Vandenberghe R, Gabel S, Scheltens P, Teunissen CE, Engelborghs S, Frisoni G, Blin O, Richardson JC, Bordet R, ... ... Lovestone S, et al. Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset. Frontiers in Aging Neuroscience. 14: 840651. PMID 35386118 DOI: 10.3389/fnagi.2022.840651 |
0.372 |
|
| 2022 |
Visser PJ, Reus LM, Gobom J, Jansen I, Dicks E, van der Lee SJ, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuevo JL, Engelborghs S, Freund-Levi Y, ... ... Lovestone S, et al. Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease. Molecular Neurodegeneration. 17: 27. PMID 35346299 DOI: 10.1186/s13024-022-00521-3 |
0.333 |
|
| 2022 |
Neumann A, Küçükali F, Bos I, Vos SJB, Engelborghs S, De Pooter T, Joris G, De Rijk P, De Roeck E, Tsolaki M, Verhey F, Martinez-Lage P, Tainta M, Frisoni G, Blin O, ... ... Lovestone S, et al. Rare variants in IFFO1, DTNB, NLRC3 and SLC22A10 associate with Alzheimer's disease CSF profile of neuronal injury and inflammation. Molecular Psychiatry. PMID 35173266 DOI: 10.1038/s41380-022-01437-6 |
0.315 |
|
| 2021 |
Xu J, Green R, Kim M, Lord J, Ebshiana A, Westwood S, Baird AL, Nevado-Holgado AJ, Shi L, Hye A, Snowden SG, Bos I, Vos SJB, Vandenberghe R, Teunissen CE, ... ... Lovestone S, et al. Sex-Specific Metabolic Pathways Were Associated with Alzheimer's Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Cohort. Biomedicines. 9. PMID 34829839 DOI: 10.3390/biomedicines9111610 |
0.349 |
|
| 2021 |
Park JY, Lee D, Lee JJ, Gim J, Gunasekaran TI, Choi KY, Kang S, Do AR, Jo J, Park J, Park K, Li D, Lee S, Kim H, Dhanasingh I, ... ... Lovestone S, et al. A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages. Translational Psychiatry. 11: 590. PMID 34785643 DOI: 10.1038/s41398-021-01680-5 |
0.373 |
|
| 2021 |
Kern DM, Lovestone S, Cepeda MS. Treatment with TNF-α inhibitors versus methotrexate and the association with dementia and Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 7: e12163. PMID 34584936 DOI: 10.1002/trc2.12163 |
0.313 |
|
| 2021 |
Tijms BM, Gobom J, Teunissen C, Dobricic V, Tsolaki M, Verhey F, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuévo JL, Engelborghs S, Freund-Levi Y, Froelich L, Bertram L, ... Lovestone S, et al. CSF Proteomic Alzheimer's Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals. Proteomes. 9. PMID 34449748 DOI: 10.3390/proteomes9030036 |
0.37 |
|
| 2021 |
Shi L, Buckley NJ, Bos I, Engelborghs S, Sleegers K, Frisoni GB, Wallin A, Lléo A, Popp J, Martinez-Lage P, Legido-Quigley C, Barkhof F, Zetterberg H, Visser PJ, Bertram L, ... Lovestone S, et al. Plasma Proteomic Biomarkers Relating to Alzheimer's Disease: A Meta-Analysis Based on Our Own Studies. Frontiers in Aging Neuroscience. 13: 712545. PMID 34366831 DOI: 10.3389/fnagi.2021.712545 |
0.375 |
|
| 2021 |
Hong S, Dobricic V, Ohlei O, Bos I, Vos SJB, Prokopenko D, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Gabel S, Scheltens P, Teunissen CE, Engelborghs S, Frisoni G, ... ... Lovestone S, et al. TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33991015 DOI: 10.1002/alz.12330 |
0.344 |
|
| 2021 |
Martín-Sánchez A, Piñero J, Nonell L, Arnal M, Ribe EM, Nevado-Holgado A, Lovestone S, Sanz F, Furlong LI, Valverde O. Comorbidity between Alzheimer's disease and major depression: a behavioural and transcriptomic characterization study in mice. Alzheimer's Research & Therapy. 13: 73. PMID 33795014 DOI: 10.1186/s13195-021-00810-x |
0.304 |
|
| 2021 |
Shi L, Winchester LM, Westwood S, Baird AL, Anand SN, Buckley NJ, Hye A, Ashton NJ, Bos I, Vos SJB, Kate MT, Scheltens P, Teunissen CE, Vandenberghe R, Gabel S, ... ... Lovestone S, et al. Replication study of plasma proteins relating to Alzheimer's pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33792144 DOI: 10.1002/alz.12322 |
0.611 |
|
| 2021 |
Simrén J, Leuzy A, Karikari TK, Hye A, Benedet AL, Lantero-Rodriguez J, Mattsson-Carlgren N, Schöll M, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Aarsland D, et al. The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33491853 DOI: 10.1002/alz.12283 |
0.603 |
|
| 2020 |
Tijms BM, Gobom J, Reus L, Jansen I, Hong S, Dobricic V, Kilpert F, Ten Kate M, Barkhof F, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, ... ... Lovestone S, et al. Pathophysiological subtypes of Alzheimer's disease based on cerebrospinal fluid proteomics. Brain : a Journal of Neurology. 143: 3776-3792. PMID 33439986 DOI: 10.1093/brain/awaa325 |
0.428 |
|
| 2020 |
Birkenbihl C, Salimi Y, Domingo-Fernándéz D, Lovestone S, Fröhlich H, Hofmann-Apitius M. Evaluating the Alzheimer's disease data landscape. Alzheimer's & Dementia (New York, N. Y.). 6: e12102. PMID 33344750 DOI: 10.1002/trc2.12102 |
0.314 |
|
| 2020 |
Kurbatova N, Garg M, Whiley L, Chekmeneva E, Jiménez B, Gómez-Romero M, Pearce J, Kimhofer T, D'Hondt E, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Aarsland D, ... ... Lovestone S, et al. Urinary metabolic phenotyping for Alzheimer's disease. Scientific Reports. 10: 21745. PMID 33303834 DOI: 10.1038/s41598-020-78031-9 |
0.607 |
|
| 2020 |
Birkenbihl C, Westwood S, Shi L, Nevado-Holgado A, Westman E, Lovestone S, Hofmann-Apitius M. ANMerge: A Comprehensive and Accessible Alzheimer's Disease Patient-Level Dataset. Journal of Alzheimer's Disease : Jad. PMID 33285634 DOI: 10.3233/JAD-200948 |
0.348 |
|
| 2020 |
Hong S, Prokopenko D, Dobricic V, Kilpert F, Bos I, Vos SJB, Tijms BM, Andreasson U, Blennow K, Vandenberghe R, Cleynen I, Gabel S, Schaeverbeke J, Scheltens P, Teunissen CE, ... ... Lovestone S, et al. Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset. Translational Psychiatry. 10: 403. PMID 33223526 DOI: 10.1038/s41398-020-01074-z |
0.394 |
|
| 2020 |
Visser PJ, Reus LM, Gobom J, Jansen I, Dicks E, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuevo JL, Engelborghs S, Freund-Levi Y, Froelich L, ... ... Lovestone S, et al. Cerebrospinal fluid total tau levels indicate aberrant neuronal plasticity in Alzheimer's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 33173883 DOI: 10.1101/2020.10.29.20211920 |
0.331 |
|
| 2020 |
Birkenbihl C, Emon MA, Vrooman H, Westwood S, Lovestone S, Hofmann-Apitius M, Fröhlich H. Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice. The Epma Journal. 11: 367-376. PMID 32843907 DOI: 10.1007/S13167-020-00216-Z |
0.349 |
|
| 2020 |
Shi L, Winchester LM, Liu BY, Killick R, Ribe EM, Westwood S, Baird AL, Buckley NJ, Hong S, Dobricic V, Kilpert F, Franke A, Kiddle S, Sattlecker M, Dobson R, ... ... Lovestone S, et al. Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology. Journal of Alzheimer's Disease : Jad. PMID 32831200 DOI: 10.3233/Jad-200208 |
0.656 |
|
| 2020 |
Nho K, Nudelman K, Allen M, Hodges A, Kim S, Risacher SL, Apostolova LG, Lin K, Lunnon K, Wang X, Burgess JD, Ertekin-Taner N, Petersen RC, Wang L, Qi Z, ... ... Lovestone S, et al. Genome-wide transcriptome analysis identifies novel dysregulated genes implicated in Alzheimer's pathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32755048 DOI: 10.1002/Alz.12092 |
0.424 |
|
| 2020 |
Roubroeks JAY, Smith AR, Smith RG, Pishva E, Ibrahim Z, Sattlecker M, Hannon EJ, Kłoszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Wahlund LO, Aarsland D, Proitsi P, ... ... Lovestone S, et al. An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene. Neurobiology of Aging. 95: 26-45. PMID 32745807 DOI: 10.1016/J.Neurobiolaging.2020.06.023 |
0.461 |
|
| 2020 |
Konijnenberg E, Tijms BM, Gobom J, Dobricic V, Bos I, Vos S, Tsolaki M, Verhey F, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Frölich L, Lovestone S, Streffer J, et al. APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease. Alzheimer's Research & Therapy. 12: 65. PMID 32460813 DOI: 10.1186/S13195-020-00628-Z |
0.469 |
|
| 2020 |
Kocagoncu E, Quinn A, Firouzian A, Cooper E, Greve A, Gunn R, Green G, Woolrich MW, Henson RN, Lovestone S, Rowe JB. Tau pathology in early Alzheimer's disease is linked to selective disruptions in neurophysiological network dynamics. Neurobiology of Aging. PMID 32280029 DOI: 10.1016/J.Neurobiolaging.2020.03.009 |
0.434 |
|
| 2020 |
Newby D, Prieto-Alhambra D, Duarte-Salles T, Ansell D, Pedersen L, van der Lei J, Mosseveld M, Rijnbeek P, James G, Alexander M, Egger P, Podhorna J, Stewart R, Perera G, Avillach P, ... ... Lovestone S, et al. Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study. Alzheimer's Research & Therapy. 12: 38. PMID 32252806 DOI: 10.1186/S13195-020-00606-5 |
0.309 |
|
| 2020 |
Westwood S, Baird AL, Anand SN, Nevado-Holgado AJ, Kormilitzin A, Shi L, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Baker S, Buckley NJ, Ten Kate M, Scheltens P, ... ... Lovestone S, et al. Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort. Journal of Alzheimer's Disease : Jad. PMID 31985466 DOI: 10.3233/Jad-190434 |
0.651 |
|
| 2019 |
Park YH, Hodges A, Risacher SL, Lin K, Jang JW, Ahn S, Kim S, Lovestone S, Simmons A, Weiner MW, Saykin AJ, Nho K. Dysregulated Fc gamma receptor-mediated phagocytosis pathway in Alzheimer's disease: network-based gene expression analysis. Neurobiology of Aging. PMID 31901293 DOI: 10.1016/J.Neurobiolaging.2019.12.001 |
0.437 |
|
| 2019 |
Stamate D, Kim M, Proitsi P, Westwood S, Baird A, Nevado-Holgado A, Hye A, Bos I, Vos SJB, Vandenberghe R, Teunissen CE, Kate MT, Scheltens P, Gabel S, Meersmans K, ... ... Lovestone S, et al. A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort. Alzheimer's & Dementia (New York, N. Y.). 5: 933-938. PMID 31890857 DOI: 10.1016/J.Trci.2019.11.001 |
0.426 |
|
| 2019 |
Lovestone S, Manji HK. Will We Have a Drug for Alzheimer's Disease by 2030? The View From Pharma. Clinical Pharmacology and Therapeutics. PMID 31758815 DOI: 10.1002/Cpt.1685 |
0.396 |
|
| 2019 |
Howard R, Zubko O, Bradley R, Harper E, Pank L, O'Brien J, Fox C, Tabet N, Livingston G, Bentham P, McShane R, Burns A, Ritchie C, Reeves S, Lovestone S, et al. Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease: A Randomized Clinical Trial. Jama Neurology. PMID 31738372 DOI: 10.1001/Jamaneurol.2019.3762 |
0.461 |
|
| 2019 |
van Maurik IS, Vos SJ, Bos I, Bouwman FH, Teunissen CE, Scheltens P, Barkhof F, Frolich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Frisoni GB, ... ... Lovestone S, et al. Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study. The Lancet. Neurology. PMID 31526625 DOI: 10.1016/S1474-4422(19)30283-2 |
0.365 |
|
| 2019 |
Mancuso R, Fryatt G, Cleal M, Obst J, Pipi E, Monzón-Sandoval J, Ribe E, Winchester L, Webber C, Nevado A, Jacobs T, Austin N, Theunis C, Grauwen K, Daniela Ruiz E, ... ... Lovestone S, et al. CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice. Brain : a Journal of Neurology. PMID 31504240 DOI: 10.1093/Brain/Awz241 |
0.611 |
|
| 2019 |
Shi L, Westwood S, Baird AL, Winchester L, Dobricic V, Kilpert F, Hong S, Franke A, Hye A, Ashton NJ, Morgan AR, Bos I, Vos SJB, Buckley NJ, Kate MT, ... ... Lovestone S, et al. Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31495601 DOI: 10.1016/J.Jalz.2019.06.4951 |
0.599 |
|
| 2019 |
Duthie A, van Aalten L, MacDonald C, McNeilly A, Gallagher J, Geddes J, Lovestone S, Sutherland C. Recruitment, Retainment, and Biomarkers of Response; A Pilot Trial of Lithium in Humans With Mild Cognitive Impairment. Frontiers in Molecular Neuroscience. 12: 163. PMID 31316348 DOI: 10.3389/Fnmol.2019.00163 |
0.39 |
|
| 2019 |
Mauricio R, Benn C, Davis J, Dawson G, Dawson LA, Evans A, Fox N, Gallacher J, Hutton M, Isaac J, Jones DNC, Jones L, Lalli G, Libri V, Lovestone S, et al. Tackling gaps in developing life-changing treatments for dementia. Alzheimer's & Dementia (New York, N. Y.). 5: 241-253. PMID 31297438 DOI: 10.1016/J.Trci.2019.05.001 |
0.357 |
|
| 2019 |
Kim M, Snowden S, Suvitaival T, Ali A, Merkler DJ, Ahmad T, Westwood S, Baird A, Proitsi P, Nevado-Holgado A, Hye A, Bos I, Vos S, Vandenberghe R, Teunissen C, ... ... Lovestone S, et al. Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31078433 DOI: 10.1016/J.Jalz.2019.03.004 |
0.651 |
|
| 2019 |
Nevado-Holgado AJ, Ribe E, Thei L, Furlong L, Mayer MA, Quan J, Richardson JC, Cavanagh J, Consortium N, Lovestone S. Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer's Disease Therapeutic Development. Cells. 8. PMID 31072055 DOI: 10.3390/Cells8050425 |
0.45 |
|
| 2019 |
Morgan AR, Touchard S, Leckey C, O'Hagan C, Nevado-Holgado AJ, Barkhof F, Bertram L, Blin O, Bos I, Dobricic V, Engelborghs S, Frisoni G, Frölich L, Gabel S, ... ... Lovestone S, et al. Inflammatory biomarkers in Alzheimer's disease plasma. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31047856 DOI: 10.1016/J.Jalz.2019.03.007 |
0.452 |
|
| 2019 |
Koychev I, Lawson J, Chessell T, Mackay C, Gunn R, Sahakian B, Rowe JB, Thomas AJ, Rochester L, Chan D, Tom B, Malhotra P, Ballard C, Chessell I, Ritchie CW, ... ... Lovestone S, et al. Deep and Frequent Phenotyping study protocol: an observational study in prodromal Alzheimer's disease. Bmj Open. 9: e024498. PMID 30904851 DOI: 10.1136/Bmjopen-2018-024498 |
0.441 |
|
| 2019 |
Startin CM, Ashton NJ, Hamburg S, Hithersay R, Wiseman FK, Mok KY, Hardy J, Lleó A, Lovestone S, Parnetti L, Zetterberg H, Hye A, Strydom A. Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease. Alzheimer's Research & Therapy. 11: 26. PMID 30902060 DOI: 10.1186/S13195-019-0477-0 |
0.657 |
|
| 2019 |
Foster EM, Dangla-Valls A, Lovestone S, Ribe EM, Buckley NJ. Clusterin in Alzheimer's Disease: Mechanisms, Genetics, and Lessons From Other Pathologies. Frontiers in Neuroscience. 13: 164. PMID 30872998 DOI: 10.3389/Fnins.2019.00164 |
0.494 |
|
| 2019 |
Bos I, Vos S, Verhey F, Scheltens P, Teunissen C, Engelborghs S, Sleegers K, Frisoni G, Blin O, Richardson JC, Bordet R, Tsolaki M, Popp J, Peyratout G, Martinez-Lage P, ... ... Lovestone S, et al. Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30853464 DOI: 10.1016/J.Jalz.2019.01.004 |
0.432 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Lovestone S, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2 |
0.307 |
|
| 2019 |
Ashton NJ, Nevado-Holgado AJ, Barber IS, Lynham S, Gupta V, Chatterjee P, Goozee K, Hone E, Pedrini S, Blennow K, Schöll M, Zetterberg H, Ellis KA, Bush AI, Rowe CC, ... ... Lovestone S, et al. A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease. Science Advances. 5: eaau7220. PMID 30775436 DOI: 10.1126/Sciadv.Aau7220 |
0.633 |
|
| 2019 |
Ashton NJ, Leuzy A, Lim YM, Troakes C, Hortobágyi T, Höglund K, Aarsland D, Lovestone S, Schöll M, Blennow K, Zetterberg H, Hye A. Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration. Acta Neuropathologica Communications. 7: 5. PMID 30626432 DOI: 10.1186/S40478-018-0649-3 |
0.627 |
|
| 2019 |
Visser PJ, Gobom J, Reus LM, Jansen IE, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Lleó A, Molinuevo JL, Engelborghs S, Lovestone S, Streffer J, Vos SJB, et al. P4-525: Association Of Csf Tau With Hyperplasticity In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.072 |
0.472 |
|
| 2019 |
Park YH, Hodges A, Risacher SL, Lin K, Lovestone S, Simmons A, Weiner MW, Saykin AJ, Nho K. Ic-P-057: Dysregulated Fc Gamma R-Mediated Phagocytosis Pathway In Alzheimer'S Disease: Network-Based Gene Expression Analysis Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4795 |
0.349 |
|
| 2019 |
Shi L, Nevado-Holgado AJ, Liu BY, Killick R, Ribe EM, Dixit A, Kiddle SJ, Sattlecker M, Dobson RJB, Cuadrado A, Lovestone S, AddNeuroMed, Consortia E. P3-245: Dkk1 Overexpression In Vitro Nominates Proteins Predicting Alzheimer'S Pathology In Blood Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3275 |
0.386 |
|
| 2019 |
Tijms BM, Gobom J, Blennow K, Tsolaki M, Verhey FRJ, Popp J, Martinez-Lage P, Vandenberghe R, Poesen K, Lleó A, Engelborghs S, Bertram L, Molinuevo JL, Lovestone S, Streffer J, et al. P2-242: Pathophysiological Subtypes Of Alzheimer'S Disease Based On Cerebrospinal Fluid Proteomics Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2649 |
0.429 |
|
| 2018 |
Boccardi V, Westman E, Pelini L, Lindberg O, Muehlboeck JS, Simmons A, Tarducci R, Floridi P, Chiarini P, Soininen H, Kloszewska I, Tsolaki M, Vellas B, Spenger C, Wahlund LO, ... Lovestone S, et al. Differential Associations of IL-4 With Hippocampal Subfields in Mild Cognitive Impairment and Alzheimer's Disease. Frontiers in Aging Neuroscience. 10: 439. PMID 30705627 DOI: 10.3389/Fnagi.2018.00439 |
0.351 |
|
| 2018 |
Westwood S, Baird AL, Hye A, Ashton NJ, Nevado-Holgado AJ, Anand SN, Liu B, Newby D, Bazenet C, Kiddle SJ, Ward M, Newton B, Desai K, Tan Hehir C, Zanette M, ... ... Lovestone S, et al. Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [F]-Flutemetamol PET Scan Result. Frontiers in Aging Neuroscience. 10: 409. PMID 30618716 DOI: 10.3389/Fnagi.2018.00409 |
0.646 |
|
| 2018 |
Ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Vandenberghe R, Gabel S, Schaeverbeke J, Scheltens P, Blin O, Richardson JC, Bordet R, Wallin A, Eckerstrom C, Molinuevo JL, ... ... Lovestone S, et al. MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study. Alzheimer's Research & Therapy. 10: 100. PMID 30261928 DOI: 10.1186/S13195-018-0428-1 |
0.47 |
|
| 2018 |
Koychev I, Galna B, Zetterberg H, Lawson J, Zamboni G, Ridha BH, Rowe JB, Thomas A, Howard R, Malhotra P, Ritchie C, Lovestone S, Rochester L. Aβ42/Aβ40 and Aβ42/Aβ38 Ratios Are Associated with Measures of Gait Variability and Activities of Daily Living in Mild Alzheimer's Disease: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 30198873 DOI: 10.3233/Jad-180622 |
0.477 |
|
| 2018 |
Petyuk VA, Chang R, Ramirez-Restrepo M, Beckmann ND, Henrion MYR, Piehowski PD, Zhu K, Wang S, Clarke J, Huentelman MJ, Xie F, Andreev V, Engel A, Guettoche T, Navarro L, ... ... Lovestone S, et al. The human brainome: network analysis identifies HSPA2 as a novel Alzheimer's disease target. Brain : a Journal of Neurology. PMID 30137212 DOI: 10.1093/Brain/Awy215 |
0.439 |
|
| 2018 |
Robbins JP, Perfect L, Ribe EM, Maresca M, Dangla-Valls A, Foster EM, Killick R, Nowosiad P, Reid MJ, Polit LD, Nevado AJ, Ebner D, Bohlooly-Y M, Buckley N, Pangalos MN, ... ... Lovestone S, et al. Clusterin Is Required for β-Amyloid Toxicity in Human iPSC-Derived Neurons. Frontiers in Neuroscience. 12: 504. PMID 30090055 DOI: 10.3389/Fnins.2018.00504 |
0.787 |
|
| 2018 |
Mårtensson G, Pereira JB, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Volpe G, Westman E. Stability of graph theoretical measures in structural brain networks in Alzheimer's disease. Scientific Reports. 8: 11592. PMID 30072774 DOI: 10.1038/S41598-018-29927-0 |
0.332 |
|
| 2018 |
Ritchie CW, Russ TC, Banerjee S, Barber B, Boaden A, Fox NC, Holmes C, Isaacs JD, Leroi I, Lovestone S, Norton M, O'Brien J, Pearson J, Perry R, Pickett J, et al. Correction to: The Edinburgh Consensus: preparing for the advent of disease-modifying therapies for Alzheimer's disease. Alzheimer's Research & Therapy. 10: 73. PMID 30060761 DOI: 10.1186/S13195-018-0372-0 |
0.324 |
|
| 2018 |
Ashton NJ, Ide M, Schöll M, Blennow K, Lovestone S, Hye A, Zetterberg H. No association of salivary total tau concentration with Alzheimer's disease. Neurobiology of Aging. 70: 125-127. PMID 30007161 DOI: 10.1016/J.Neurobiolaging.2018.06.014 |
0.64 |
|
| 2018 |
Bos I, Vos S, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni G, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird A, Dobson R, Legido-Quigley C, Sleegers K, ... ... Lovestone S, et al. The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics. Alzheimer's Research & Therapy. 10: 64. PMID 29980228 DOI: 10.1186/S13195-018-0396-5 |
0.465 |
|
| 2018 |
Winchester LM, Powell J, Lovestone S, Nevado-Holgado AJ. Red blood cell indices and anaemia as causative factors for cognitive function deficits and for Alzheimer's disease. Genome Medicine. 10: 51. PMID 29954452 DOI: 10.1186/S13073-018-0556-Z |
0.428 |
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| 2018 |
Mc Ardle R, Morris R, Hickey A, Del Din S, Koychev I, Gunn RN, Lawson J, Zamboni G, Ridha B, Sahakian BJ, Rowe JB, Thomas A, Zetterberg H, MacKay C, Lovestone S, et al. Gait in Mild Alzheimer's Disease: Feasibility of Multi-Center Measurement in the Clinic and Home with Body-Worn Sensors: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 29614664 DOI: 10.3233/Jad-171116 |
0.429 |
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| 2018 |
Shi L, Baird AL, Westwood S, Hye A, Dobson R, Thambisetty M, Lovestone S. A Decade of Blood Biomarkers for Alzheimer's Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication. Journal of Alzheimer's Disease : Jad. 62: 1181-1198. PMID 29562526 DOI: 10.3233/Jad-170531 |
0.409 |
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| 2018 |
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, et al. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29550519 DOI: 10.1016/J.Jalz.2018.01.017 |
0.404 |
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| 2018 |
Firouzian A, Whittington A, Searle GE, Koychev I, Zamboni G, Lovestone S, Gunn RN. Imaging Aβ and tau in early stage Alzheimer's disease with [F]AV45 and [F]AV1451. Ejnmmi Research. 8: 19. PMID 29500717 DOI: 10.1186/S13550-018-0371-Y |
0.388 |
|
| 2018 |
Poulakis K, Pereira JB, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E. Heterogeneous patterns of brain atrophy in Alzheimer's disease. Neurobiology of Aging. 65: 98-108. PMID 29455029 DOI: 10.1016/J.Neurobiolaging.2018.01.009 |
0.45 |
|
| 2018 |
Hong S, Dobricic V, Smith RG, Küçükali F, Kilpert F, Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, ... ... Lovestone S, et al. F1-02-04: Genomics And Epigenomics Analyses In The Emif-Ad Multimodal Biomarker Discovery Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2310 |
0.336 |
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| 2018 |
Bos I, Vos SJB, Verhey FRJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Tsolaki M, Popp J, Martinez-Lage P, Lleó A, Johannsen P, Freund-Levi Y, ... ... Lovestone S, et al. F1-02-01: RELATING CSF MARKERS NEUROGRANIN, NEUROFILAMENT-LIGHT AND YKL-40 TO Aβ, APOE ε4 AND COGNITION: RESULTS FROM THE EMIF-AD MULTIMODAL BIOMARKER DISCOVERY STUDY Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2307 |
0.402 |
|
| 2018 |
Kim M, Snowden SG, Ahmad T, Westwood S, Baird AL, Proitsi P, Nevado-Holgado AJ, Hye A, Ashton NJ, Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, ... ... Lovestone S, et al. P3-233: PLASMA PRIMARY FATTY AMIDES ASSOCIATE TO CSF AMYLOID LEVELS AND ALZHEIMER\textquotesingleS DISEASE PROGRESSION IN THE EMIF-AD BIOMARKER DISCOVERY COHORT Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1592 |
0.477 |
|
| 2017 |
Judge A, Garriga C, Arden NK, Lovestone S, Prieto-Alhambra D, Cooper C, Edwards CJ. Protective effect of antirheumatic drugs on dementia in rheumatoid arthritis patients. Alzheimer's & Dementia (New York, N. Y.). 3: 612-621. PMID 29201995 DOI: 10.1016/J.Trci.2017.10.002 |
0.313 |
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| 2017 |
Ritchie CW, Russ TC, Banerjee S, Barber B, Boaden A, Fox NC, Holmes C, Isaacs JD, Leroi I, Lovestone S, Norton M, O'Brien J, Pearson J, Perry R, Pickett J, et al. The Edinburgh Consensus: preparing for the advent of disease-modifying therapies for Alzheimer's disease. Alzheimer's Research & Therapy. 9: 85. PMID 29070066 DOI: 10.1186/S13195-017-0312-4 |
0.46 |
|
| 2017 |
Sellers KJ, Elliott C, Jackson J, Ghosh A, Ribe E, Rojo-Sanchís A, Jarosz-Griffiths HH, Watson IA, Xia W, Semenov M, Morin P, Hooper NM, Porter R, Preston J, Al-Shawi R, ... ... Lovestone S, et al. Amyloid beta synaptotoxicity is Wnt-planar cell polarity dependent and blocked by fasudil. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29055813 DOI: 10.1016/J.Jalz.2017.09.008 |
0.432 |
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| 2017 |
Gunn-Moore D, Kaidanovich-Beilin O, Gallego Iradi MC, Gunn-Moore F, Lovestone S. Alzheimer's disease in humans and other animals-A consequence of postreproductive life span and longevity rather than aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28972881 DOI: 10.1016/J.Jalz.2017.08.014 |
0.376 |
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| 2017 |
Horgusluoglu-Moloch E, Nho K, Risacher SL, Kim S, Foroud T, Shaw LM, Trojanowski JQ, Aisen PS, Petersen RC, Jack CR, Lovestone S, Simmons A, Weiner MW, Saykin AJ. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease. Neurobiology of Aging. 60: 92-103. PMID 28941407 DOI: 10.1016/J.Neurobiolaging.2017.08.010 |
0.46 |
|
| 2017 |
Koychev I, Gunn RN, Firouzian A, Lawson J, Zamboni G, Ridha B, Sahakian BJ, Rowe JB, Thomas A, Rochester L, Ffytche D, Howard R, Zetterberg H, MacKay C, Lovestone S, et al. PET Tau and Amyloid-β Burden in Mild Alzheimer's Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers. Journal of Alzheimer's Disease : Jad. PMID 28800330 DOI: 10.3233/Jad-170129 |
0.475 |
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| 2017 |
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Lovestone S, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
0.416 |
|
| 2017 |
Rojo AI, Pajares M, Rada P, Nuñez A, Nevado-Holgado AJ, Killik R, Van Leuven F, Ribe E, Lovestone S, Yamamoto M, Cuadrado A. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology. Redox Biology. 13: 444-451. PMID 28704727 DOI: 10.1016/J.Redox.2017.07.006 |
0.414 |
|
| 2017 |
Lupton MK, Benyamin B, Proitsi P, Nyholt DR, Ferreira MA, Montgomery GW, Heath AC, Madden PA, Medland SE, Gordon SD, Lovestone S, Tsolaki M, Kloszewska I, et al. No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28582860 DOI: 10.3233/Jad-170027 |
0.377 |
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| 2017 |
Westwood S, Liu B, Baird AL, Anand S, Nevado-Holgado AJ, Newby D, Pikkarainen M, Hallikainen M, Kuusisto J, Streffer JR, Novak G, Blennow K, Andreasson U, Zetterberg H, Smith U, ... ... Lovestone S, et al. The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology. Alzheimer's Research & Therapy. 9: 31. PMID 28441961 DOI: 10.1186/S13195-017-0258-6 |
0.445 |
|
| 2017 |
Ferreira D, Hansson O, Barroso J, Molina Y, Machado A, Hernández-Cabrera JA, Muehlboeck JS, Stomrud E, Nägga K, Lindberg O, Ames D, Kalpouzos G, Fratiglioni L, Bäckman L, Graff C, ... ... Lovestone S, et al. The interactive effect of demographic and clinical factors on hippocampal volume: A multicohort study on 1958 cognitively normal individuals. Hippocampus. PMID 28394034 DOI: 10.1002/Hipo.22721 |
0.344 |
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| 2017 |
Ritchie K, Carrière I, Su L, O'Brien JT, Lovestone S, Wells K, Ritchie CW. The midlife cognitive profiles of adults at high risk of late-onset Alzheimer's disease: The PREVENT study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28365321 DOI: 10.1016/J.Jalz.2017.02.008 |
0.407 |
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| 2017 |
Khan W, Giampietro V, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaître H, Nees F, ... ... Lovestone S, et al. A Multi-Cohort Study of ApoE ɛ4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 56: 1159-1174. PMID 28157104 DOI: 10.3233/Jad-161097 |
0.454 |
|
| 2017 |
Hibar DP, Adams HH, Jahanshad N, Chauhan G, Stein JL, Hofer E, Renteria ME, Bis JC, Arias-Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, ... ... Lovestone S, et al. Novel genetic loci associated with hippocampal volume. Nature Communications. 8: 13624. PMID 28098162 DOI: 10.1038/Ncomms13624 |
0.336 |
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| 2017 |
Nevado-Holgado AJ, Lovestone S. Determining the Molecular Pathways Underlying the Protective Effect of Non-Steroidal Anti-Inflammatory Drugs for Alzheimer's Disease: A Bioinformatics Approach. Computational and Structural Biotechnology Journal. 15: 1-7. PMID 27872687 DOI: 10.1016/J.Csbj.2016.10.003 |
0.4 |
|
| 2017 |
Winchester L, Nevado-Holgado AJ, Lovestone S. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE Alzheimer's & Dementia. 13: P221. DOI: 10.1016/J.Jalz.2017.07.099 |
0.335 |
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| 2017 |
Westwood S, Hye A, Lleó A, Nevado-Holgado AJ, Baird AL, Wallin A, Leslie A, Jimenez B, Liu BY, Legido-Quigley C, Dima D, Ruvolo D, Holmes E, D'Hondt E, Westman E, ... ... Lovestone S, et al. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION Alzheimer's & Dementia. 13: P174-P175. DOI: 10.1016/J.Jalz.2017.07.016 |
0.463 |
|
| 2017 |
Baird AL, Anand SN, Lovestone S. [P2-223]: MARKERS OF CIRCADIAN CLOCK FUNCTION IN ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P696-P696. DOI: 10.1016/J.Jalz.2017.06.875 |
0.419 |
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| 2017 |
Bos I, Vos SJB, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Baird AL, Legido-Quigley C, Bertram L, Barkhof F, ... ... Lovestone S, et al. European Medical Information Framework For Alzheimer’S Disease (Emif-Ad): The Biomarker Discovery Study Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.864 |
0.393 |
|
| 2017 |
Koychev IG, Gunn RN, Firouzian A, Lawson J, Zamboni G, Ridha BH, Sahakian B, Rowe JB, Thomas A, Rochester L, Ffytche D, Howard RJ, Zetterberg H, MacKay C, Lovestone S. [P1-448]: PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER's DISEASE: AN OBSERVATIONAL STUDY Alzheimer's & Dementia. 13: P456-P457. DOI: 10.1016/J.Jalz.2017.06.464 |
0.449 |
|
| 2017 |
Westwood S, Baird AL, Hye A, Bos I, Vos SJ, Vandenberghe R, Scheltens P, Engelborghs S, Frisoni GB, Molinuevo JL, Wallin A, Lleó A, Popp J, Martinez-Lage P, Snowden SG, ... ... Lovestone S, et al. [P1-289]: DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT Alzheimer's & Dementia. 13: P361-P362. DOI: 10.1016/J.Jalz.2017.06.305 |
0.433 |
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| 2017 |
Redolfi A, Kate Mt, Peira E, Orlandi D, Wolz R, Lovestone S, Visser PJ, Barkhof F, Frisoni GB. Best Combinatorial Low-Cost Markers To Predict Mci Conversion: An Emif-Ad Federation Study Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.2094 |
0.35 |
|
| 2017 |
Lawson J, Murray M, Zamboni G, Koychev IG, Ritchie CW, Ridha BH, Rowe JB, Thomas A, Ffytche DH, Howard RJ, Sahakian B, Rochester L, Gunn RN, Mackay CE, Nobre AC, ... ... Lovestone S, et al. [P4-033]: DEEP AND FREQUENT PHENOTYPING: A FEASIBILITY STUDY FOR EXPERIMENTAL MEDICINE IN DEMENTIA Alzheimer's & Dementia. 13: P1268-P1269. DOI: 10.1016/J.Jalz.2017.06.1897 |
0.335 |
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| 2017 |
Barber IS, Nevado-Holgado AJ, Lovestone S. [P3-232]: A PARKINSON's DISEASE PROTEIN BIOMARKER PANEL USING THE SOMAMER ASSAY AND MACHINE LEARNING Alzheimer's & Dementia. 13: P1027-P1027. DOI: 10.1016/J.Jalz.2017.06.1445 |
0.323 |
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| 2017 |
Ribe EM, Smith R, Farrar T, Sacks S, Meert T, Lovestone S. COULD COMPLEMENT INHIBITION BE A GOOD THERAPEUTIC TARGET IN ALZHEIMER’S DISEASE? Alzheimer's & Dementia. 13: P950. DOI: 10.1016/J.Jalz.2017.06.1261 |
0.3 |
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| 2017 |
Koychev IG, Gunn RN, Firouzian A, Lawson J, Zamboni G, Ridha BH, Sahakian B, Rowe JB, Thomas A, Rochester L, Ffytche D, Howard RJ, Zetterberg H, MacKay C, Lovestone S. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY Alzheimer's & Dementia. 13: P243. DOI: 10.1016/J.Jalz.2017.06.094 |
0.398 |
|
| 2016 |
Kim M, Nevado-Holgado A, Whiley L, Snowden SG, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Thambisetty M, Dobson RJ, Powell JF, Lupton MK, Simmons A, Velayudhan L, ... Lovestone S, et al. Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27911300 DOI: 10.3233/Jad-160645 |
0.445 |
|
| 2016 |
Knapp M, Chua KC, Broadbent M, Chang CK, Fernandez JL, Milea D, Romeo R, Lovestone S, Spencer M, Thompson G, Stewart R, Hayes RD. Predictors of care home and hospital admissions and their costs for older people with Alzheimer's disease: findings from a large London case register. Bmj Open. 6: e013591. PMID 27864252 DOI: 10.1136/Bmjopen-2016-013591 |
0.336 |
|
| 2016 |
Ribe EM, Lovestone S. Insulin signalling in Alzheimer's disease and diabetes: from epidemiology to molecular links. Journal of Internal Medicine. 280: 430-442. PMID 27739227 DOI: 10.1111/Joim.12534 |
0.388 |
|
| 2016 |
Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, ... ... Lovestone S, et al. Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nature Neuroscience. PMID 27694991 DOI: 10.1038/Nn.4398 |
0.317 |
|
| 2016 |
Proitsi P, Kim M, Whiley L, Simmons A, Sattlecker M, Velayudhan L, Lupton MK, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Powell JF, Dobson RJ, et al. Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27693183 DOI: 10.1016/J.Jalz.2016.08.003 |
0.447 |
|
| 2016 |
Hakobyan S, Harding K, Aiyaz M, Hye A, Dobson R, Baird A, Liu B, Harris CL, Lovestone S, Morgan BP. Complement Biomarkers as Predictors of Disease Progression in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27567854 DOI: 10.3233/Jad-160420 |
0.487 |
|
| 2016 |
Dacks PA, Armstrong JJ, Brannan SK, Carman AJ, Green AM, Kirkman MS, Krakoff LR, Kuller LH, Launer LJ, Lovestone S, Merikle E, Neumann PJ, Rockwood K, Shineman DW, Stefanacci RG, et al. A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline. Alzheimer's Research & Therapy. 8: 33. PMID 27543171 DOI: 10.1186/S13195-016-0200-3 |
0.386 |
|
| 2016 |
Allen GI, Amoroso N, Anghel C, Balagurusamy V, Bare CJ, Beaton D, Bellotti R, Bennett DA, Boehme K, Boutros PC, Caberlotto L, Caloian C, Campbell F, Neto EC, Chang YC, ... ... Lovestone S, et al. Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27079753 DOI: 10.1016/J.Jalz.2016.02.006 |
0.433 |
|
| 2016 |
Westwood S, Leoni E, Hye A, Lynham S, Khondoker MR, Ashton NJ, Kiddle SJ, Baird AL, Sainz-Fuertes R, Leung R, Graf J, Hehir CT, Baker D, Cereda C, Bazenet C, ... ... Lovestone S, et al. Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly. Journal of Alzheimer's Disease : Jad. PMID 27031486 DOI: 10.3233/Jad-151155 |
0.646 |
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| 2016 |
O'Bryant SE, Lista S, Rissman RA, Edwards M, Zhang F, Hall J, Zetterberg H, Lovestone S, Gupta V, Graff-Radford N, Martins R, Jeromin A, Waring S, Oh E, King M, et al. Comparing biological markers of Alzheimer's disease across blood fraction and platforms: Comparing apples to oranges. Alzheimer's & Dementia (Amsterdam, Netherlands). 3: 27-34. PMID 27019866 DOI: 10.1016/J.Dadm.2015.12.003 |
0.469 |
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| 2016 |
Lupton MK, Strike L, Hansell NK, Wen W, Mather KA, Armstrong NJ, Thalamuthu A, McMahon KL, de Zubicaray GI, Assareh AA, Simmons A, Proitsi P, Powell JF, Montgomery GW, Hibar DP, ... ... Lovestone S, et al. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume. Neurobiology of Aging. 40: 68-77. PMID 26973105 DOI: 10.1016/J.Neurobiolaging.2015.12.023 |
0.424 |
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| 2016 |
Liang HC, Russell C, Mitra V, Chung R, Hye A, Bazenet C, Lovestone S, Pike I, Ward M. Correction to "Glycosylation of Human Plasma Clusterin Yields a Novel Candidate Biomarker of Alzheimer's Disease". Journal of Proteome Research. PMID 26828705 DOI: 10.1021/Acs.Jproteome.6B00080 |
0.324 |
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| 2016 |
Voyle N, Kim M, Proitsi P, Ashton NJ, Baird AL, Bazenet C, Hye A, Westwood S, Chung R, Ward M, Rabinovici GD, Lovestone S, Breen G, Legido-Quigley C, Dobson RJ, et al. Blood metabolite markers of neocortical amyloid-β burden: discovery and enrichment using candidate proteins. Translational Psychiatry. 6: e719. PMID 26812040 DOI: 10.1038/Tp.2015.205 |
0.44 |
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| 2016 |
Orellana C, Ferreira D, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E. Measuring Global Brain Atrophy with the Brain Volume/Cerebrospinal Fluid Index: Normative Values, Cut-Offs and Clinical Associations. Neuro-Degenerative Diseases. 16: 77-86. PMID 26726737 DOI: 10.1159/000442443 |
0.408 |
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| 2016 |
Liu BY, Killick R, Ribe E, Dixit A, Kiddle SJ, Sattlecker M, Dobson RJ, Cuadrado A, Lovestone S. P1-196: Empirical Feature Selection for Biomarker and Disease Signature Discovery: DKK1 Overexpression IN VITRO
Nominates Proteins Associated with Alzheimer’S IN VIVO Alzheimer's & Dementia. 12: P479-P479. DOI: 10.1016/J.Jalz.2016.06.944 |
0.343 |
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| 2016 |
Baird AL, Hye A, Westwood S, Ashton NJ, Liu BY, Bazenet C, Kiddle SJ, Ward M, Thambisetty M, Scheltens P, Teunissen CE, Galimberti D, Lleo A, Parnetti L, Desai K, ... ... Lovestone S, et al. Cross-Sectional Studies Of Plasma Proteomic Biomarkers Relating To Pet Amyloid And Csf Amyloid And Tau Alzheimers & Dementia. 12: 321. DOI: 10.1016/J.Jalz.2016.06.580 |
0.356 |
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| 2016 |
Scheltens P, Blennow K, Rowe CC, Fox NC, Lovestone S, DeCarli C, Snyder HM, Amouyel P, Carrillo MC. FTS3-01-03: Biomarkers for Vascular Contributions to Dementia Alzheimer's & Dementia. 12: P276-P277. DOI: 10.1016/J.Jalz.2016.06.2386 |
0.325 |
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| 2016 |
Nho K, Kim S, Risacher SL, Apostolova LG, Lin K, Keohane A, Lunnon K, Hodges A, Allen M, Wang X, Burgess JD, Ertekin-Taner N, Petersen RC, Soares H, Singh P, ... ... Lovestone S, et al. IC-P-074: Genome-Wide Meta-Analysis of Transcriptome Profiling Identifies Novel Dysregulated Genes Implicated in Alzheimer’s Disease Alzheimer's & Dementia. 12: P58-P60. DOI: 10.1016/J.Jalz.2016.06.104 |
0.302 |
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| 2016 |
Pereira JB, Mijalkov M, Kakaei E, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Lovestone S, Simmons A, Wahlund L, Volpe G, Westman E. IC-P-038: Abnormal Network Organization in Patients with Mild Cognitive Impairment and Alzheimer's Disease Alzheimer's & Dementia. 12: P34-P34. DOI: 10.1016/J.Jalz.2016.06.048 |
0.373 |
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| 2015 |
Kerr F, Augustin H, Piper MDW, Gandy C, Allen MJ, Lovestone S, Partridge L. Erratum to "Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease." [Neurobiol. Aging 32 (2011) 1977-1989]. Neurobiology of Aging. 36: 2331. PMID 28843333 DOI: 10.1016/J.Neurobiolaging.2015.05.007 |
0.354 |
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| 2015 |
Ashton NJ, Kiddle SJ, Graf J, Ward M, Baird AL, Hye A, Westwood S, Wong KV, Dobson RJ, Rabinovici GD, Miller BL, Rosen HJ, Torres A, Zhang Z, Thurfjell L, ... ... Lovestone S, et al. Blood protein predictors of brain amyloid for enrichment in clinical trials? Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 48-60. PMID 27239491 DOI: 10.1016/J.Dadm.2014.11.005 |
0.62 |
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| 2015 |
Ritchie CW, Molinuevo JL, Truyen L, Satlin A, Van der Geyten S, Lovestone S. Development of interventions for the secondary prevention of Alzheimer's dementia: the European Prevention of Alzheimer's Dementia (EPAD) project. The Lancet. Psychiatry. PMID 26683239 DOI: 10.1016/S2215-0366(15)00454-X |
0.428 |
|
| 2015 |
Baird AL, Westwood S, Lovestone S. Blood-Based Proteomic Biomarkers of Alzheimer's Disease Pathology. Frontiers in Neurology. 6: 236. PMID 26635716 DOI: 10.3389/Fneur.2015.00236 |
0.452 |
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| 2015 |
Sattlecker M, Khondoker M, Proitsi P, Williams S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Dobson RJ. Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26599049 DOI: 10.3233/Jad-140669 |
0.474 |
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| 2015 |
Ferreira D, Cavallin L, Granberg T, Lindberg O, Aguilar C, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E. Quantitative validation of a visual rating scale for frontal atrophy: associations with clinical status, APOE e4, CSF biomarkers and cognition. European Radiology. PMID 26560730 DOI: 10.1007/S00330-015-4101-9 |
0.308 |
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| 2015 |
Falahati F, Ferreira D, Soininen H, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Lovestone S, Eriksdotter M, Wahlund LO, Simmons A, Westman E. The Effect of Age Correction on Multivariate Classification in Alzheimer's Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects. Brain Topography. PMID 26440606 DOI: 10.1007/S10548-015-0455-1 |
0.389 |
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| 2015 |
Stephenson D, Hu MT, Romero K, Breen K, Burn D, Ben-Shlomo Y, Bhattaram A, Isaac M, Venuto C, Kubota K, Little MA, Friend S, Lovestone S, Morris HR, Grosset D, et al. Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease1. Journal of Parkinson's Disease. 5: 581-94. PMID 26406139 DOI: 10.3233/Jpd-150570 |
0.346 |
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| 2015 |
Dell'Acqua F, Khan W, Gottlieb N, Giampietro V, Ginestet C, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, ... ... Lovestone S, et al. Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE ɛ4 and ɛ2 Alleles in Young Healthy Adolescents. Journal of Alzheimer's Disease : Jad. 47: 977-84. PMID 26401776 DOI: 10.3233/Jad-140519 |
0.331 |
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| 2015 |
Chiam JT, Lunnon K, Voyle N, Proitsi P, Coppola G, Geschwind D, Nelson S, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Hodges A, Lovestone S, et al. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 47: 741-50. PMID 26401708 DOI: 10.3233/Jad-150289 |
0.462 |
|
| 2015 |
Khan W, Aguilar C, Kiddle SJ, Doyle O, Thambisetty M, Muehlboeck S, Sattlecker M, Newhouse S, Lovestone S, Dobson R, Giampietro V, Westman E, Simmons A. A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease. Plos One. 10: e0134368. PMID 26284520 DOI: 10.1371/Journal.Pone.0134368 |
0.452 |
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| 2015 |
Andrieu S, Coley N, Lovestone S, Aisen PS, Vellas B. Prevention of sporadic Alzheimer's disease: lessons learned from clinical trials and future directions. The Lancet. Neurology. 14: 926-44. PMID 26213339 DOI: 10.1016/S1474-4422(15)00153-2 |
0.351 |
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| 2015 |
Kiddle SJ, Steves CJ, Mehta M, Simmons A, Xu X, Newhouse S, Sattlecker M, Ashton NJ, Bazenet C, Killick R, Adnan J, Westman E, Nelson S, Soininen H, Kloszewska I, ... ... Lovestone S, et al. Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes. Translational Psychiatry. 5: e584. PMID 26080319 DOI: 10.1038/Tp.2015.78 |
0.407 |
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| 2015 |
Voyle N, Baker D, Burnham SC, Covin A, Zhang Z, Sangurdekar DP, Tan Hehir CA, Bazenet C, Lovestone S, Kiddle S, Dobson RJ. Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology. Journal of Alzheimer's Disease : Jad. PMID 25881911 DOI: 10.3233/Jad-150020 |
0.397 |
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| 2015 |
Vaudano E, Vannieuwenhuyse B, Van Der Geyten S, van der Lei J, Visser PJ, Streffer J, Ritchie C, McHale D, Lovestone S, Hofmann-Apitius M, Truyen L, Goldman M. Boosting translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25754460 DOI: 10.1016/J.Jalz.2015.02.002 |
0.417 |
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| 2015 |
Ferreira D, Cavallin L, Larsson EM, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E. Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment. Journal of Internal Medicine. PMID 25752192 DOI: 10.1111/Joim.12358 |
0.364 |
|
| 2015 |
Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, ... ... Lovestone S, et al. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage. Brain : a Journal of Neurology. 138: 1327-38. PMID 25693589 DOI: 10.1093/Brain/Awv029 |
0.485 |
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| 2015 |
Khondoker M, Newhouse S, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Lovestone S, Dobson R, Simmons A. Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts. Journal of Alzheimer's Disease : Jad. 45: 851-64. PMID 25649652 DOI: 10.3233/Jad-142214 |
0.464 |
|
| 2015 |
Proitsi P, Kim M, Whiley L, Pritchard M, Leung R, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Sham P, Lovestone S, Powell JF, Dobson RJ, Legido-Quigley C. Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease. Translational Psychiatry. 5: e494. PMID 25585166 DOI: 10.1038/Tp.2014.127 |
0.447 |
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| 2015 |
Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Lovestone S, et al. Protective variant for hippocampal atrophy identified by whole exome sequencing. Annals of Neurology. 77: 547-52. PMID 25559091 DOI: 10.1002/Ana.24349 |
0.397 |
|
| 2015 |
Lovestone S, Boada M, Dubois B, Hüll M, Rinne JO, Huppertz HJ, Calero M, Andrés MV, Gómez-Carrillo B, León T, del Ser T. A phase II trial of tideglusib in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 45: 75-88. PMID 25537011 DOI: 10.3233/Jad-141959 |
0.407 |
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| 2015 |
Hallaq R, Volpicelli F, Cuchillo-Ibanez I, Hooper C, Mizuno K, Uwanogho D, Causevic M, Asuni A, To A, Soriano S, Giese KP, Lovestone S, Killick R. The Notch intracellular domain represses CRE-dependent transcription. Cellular Signalling. 27: 621-9. PMID 25479589 DOI: 10.1016/J.Cellsig.2014.11.034 |
0.606 |
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| 2015 |
O'Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C, Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, et al. Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 549-60. PMID 25282381 DOI: 10.1016/J.Jalz.2014.08.099 |
0.406 |
|
| 2015 |
Hall A, Muñoz-Ruiz M, Mattila J, Koikkalainen J, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Visser PJ, Lötjonen J, Soininen H. Generalizability of the disease state index prediction model for identifying patients progressing from mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 79-92. PMID 25201784 DOI: 10.3233/Jad-140942 |
0.421 |
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| 2015 |
Menni C, Kiddle SJ, Mangino M, Viñuela A, Psatha M, Steves C, Sattlecker M, Buil A, Newhouse S, Nelson S, Williams S, Voyle N, Soininen H, Kloszewska I, Mecocci P, ... ... Lovestone S, et al. Circulating Proteomic Signatures of Chronological Age. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 70: 809-16. PMID 25123647 DOI: 10.1093/Gerona/Glu121 |
0.326 |
|
| 2015 |
Proitsi P, Min K, Whiley L, Newhouse S, Johnston C, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Sham P, Lovestone S, Powell JF, Quigley CL, Dobson RJB. Genetic influences on metabolite levels in Alzheimer’s disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.373 |
0.308 |
|
| 2015 |
Lovestone S, Gallacher JE. FTS-01-04: Dementias platform UK Alzheimer's & Dementia. 11: P121-P121. DOI: 10.1016/J.Jalz.2015.07.025 |
0.346 |
|
| 2015 |
Marchant NL, Ashton NJ, Hye A, Lovestone S. P3-086: Investigation of REST protein in healthy elderly and Alzheimer's disease using a blood-based approach Alzheimer's & Dementia. 11: P652-P652. DOI: 10.1016/J.Jalz.2015.06.953 |
0.411 |
|
| 2014 |
Tan GM, Beacher F, Daly E, Horder J, Prasher V, Hanney ML, Morris R, Lovestone S, Murphy KC, Simmons A, Murphy DG. Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS). Journal of Neurodevelopmental Disorders. 6: 42. PMID 25937842 DOI: 10.1186/1866-1955-6-42 |
0.369 |
|
| 2014 |
Lovestone S. Blood biomarkers for Alzheimer's disease. Genome Medicine. 6: 65. PMID 25473432 DOI: 10.1186/S13073-014-0065-7 |
0.447 |
|
| 2014 |
Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, et al. FASTKD2 is associated with memory and hippocampal structure in older adults. Molecular Psychiatry. PMID 25385369 DOI: 10.1038/Mp.2014.142 |
0.325 |
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| 2014 |
Lebedev AV, Westman E, Van Westen GJ, Kramberger MG, Lundervold A, Aarsland D, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Simmons A. Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness. Neuroimage. Clinical. 6: 115-25. PMID 25379423 DOI: 10.1016/J.Nicl.2014.08.023 |
0.413 |
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| 2014 |
Khan W, Westman E, Jones N, Wahlund LO, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Spenger C, Lovestone S, Muehlboeck JS, Simmons A. Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts. Brain Topography. PMID 25370484 DOI: 10.1016/J.Jalz.2013.05.547 |
0.454 |
|
| 2014 |
Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B, Williams J, ... ... Lovestone S, et al. Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a mendelian randomization analysis. Plos Medicine. 11: e1001713. PMID 25226301 DOI: 10.1371/Journal.Pmed.1001713 |
0.396 |
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| 2014 |
Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I, ... ... Lovestone S, et al. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease. Neurobiology of Aging. 35: 2883.e3-2883.e10. PMID 25150574 DOI: 10.1016/J.Neurobiolaging.2014.07.023 |
0.31 |
|
| 2014 |
Doyle OM, Westman E, Marquand AF, Mecocci P, Vellas B, Tsolaki M, K?oszewska I, Soininen H, Lovestone S, Williams SC, Simmons A. Predicting progression of Alzheimer's disease using ordinal regression. Plos One. 9: e105542. PMID 25141298 DOI: 10.1371/Journal.Pone.0105542 |
0.472 |
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| 2014 |
Lunnon K, Smith R, Hannon E, De Jager PL, Srivastava G, Volta M, Troakes C, Al-Sarraj S, Burrage J, Macdonald R, Condliffe D, Harries LW, Katsel P, Haroutunian V, Kaminsky Z, ... ... Lovestone S, et al. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nature Neuroscience. 17: 1164-70. PMID 25129077 DOI: 10.1038/Nn.3782 |
0.506 |
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| 2014 |
Aguilar C, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Wahlund LO, Simmons A, Westman E. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort. Frontiers in Aging Neuroscience. 6: 145. PMID 25071554 DOI: 10.3389/Fnagi.2014.00145 |
0.453 |
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| 2014 |
Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K, Keohane A, Ward M, Pike I, ... ... Lovestone S, et al. Plasma proteins predict conversion to dementia from prodromal disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 799-807.e2. PMID 25012867 DOI: 10.1016/J.Jalz.2014.05.1749 |
0.636 |
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| 2014 |
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Lovestone S, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661 |
0.439 |
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| 2014 |
Sattlecker M, Kiddle SJ, Newhouse S, Proitsi P, Nelson S, Williams S, Johnston C, Killick R, Simmons A, Westman E, Hodges A, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, ... ... Lovestone S, et al. Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 724-34. PMID 24768341 DOI: 10.1016/J.Jalz.2013.09.016 |
0.464 |
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| 2014 |
Lovestone S, Smith U. Advanced glycation end products, dementia, and diabetes. Proceedings of the National Academy of Sciences of the United States of America. 111: 4743-4. PMID 24707042 DOI: 10.1073/Pnas.1402277111 |
0.417 |
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| 2014 |
Condliffe D, Wong A, Troakes C, Proitsi P, Patel Y, Chouliaras L, Fernandes C, Cooper J, Lovestone S, Schalkwyk L, Mill J, Lunnon K. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain. Neurobiology of Aging. 35: 1850-4. PMID 24679604 DOI: 10.1016/J.Neurobiolaging.2014.02.002 |
0.452 |
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| 2014 |
Mulugeta E, Vallortigara J, Francis PT, Hye A, Kalaria RN, Perry EK, Lovestone S, Ballard CG. Dynamin protein in stroke and vascular dementia. Neuroscience Letters. 563: 118-22. PMID 24486840 DOI: 10.1016/J.Neulet.2014.01.045 |
0.385 |
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| 2014 |
Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, et al. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 109-14. PMID 24365657 DOI: 10.1016/J.Jalz.2013.10.007 |
0.445 |
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| 2014 |
Khan W, Giampietro V, Ginestet C, Dell'Acqua F, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, ... ... Lovestone S, et al. No differences in hippocampal volume between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents. Journal of Alzheimer's Disease : Jad. 40: 37-43. PMID 24326516 DOI: 10.3233/Jad-131841 |
0.389 |
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| 2014 |
Paajanen T, Hänninen T, Tunnard C, Hallikainen M, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H. CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: a prospective AddNeuroMed study. Journal of Alzheimer's Disease : Jad. 39: 679-90. PMID 24246420 DOI: 10.3233/Jad-122110 |
0.406 |
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| 2014 |
Kiddle SJ, Sattlecker M, Proitsi P, Simmons A, Westman E, Bazenet C, Nelson SK, Williams S, Hodges A, Johnston C, Soininen H, KÅ‚oszewska I, Mecocci P, Tsolaki M, Vellas B, ... ... Lovestone S, et al. Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study. Journal of Alzheimer's Disease : Jad. 38: 515-31. PMID 24121966 DOI: 10.1016/J.Jalz.2013.08.178 |
0.457 |
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| 2014 |
Pereira JB, Cavallin L, Spulber G, Aguilar C, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Aarsland D, Lovestone S, Simmons A, Wahlund LO, Westman E, et al. Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs. Journal of Internal Medicine. 275: 317-30. PMID 24118559 DOI: 10.1111/Joim.12148 |
0.42 |
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| 2014 |
Proitsi P, Lee SH, Lunnon K, Keohane A, Powell J, Troakes C, Al-Sarraj S, Furney S, Soininen H, KÅ‚oszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A, et al. Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood. Neurobiology of Aging. 35: 279-90. PMID 24064185 DOI: 10.1016/J.Neurobiolaging.2013.08.002 |
0.439 |
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| 2014 |
Whiley L, Sen A, Heaton J, Proitsi P, García-Gómez D, Leung R, Smith N, Thambisetty M, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, Legido-Quigley C, et al. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease. Neurobiology of Aging. 35: 271-8. PMID 24041970 DOI: 10.1016/J.Neurobiolaging.2013.08.001 |
0.447 |
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| 2014 |
Henriksen K, O'Bryant SE, Hampel H, Trojanowski JQ, Montine TJ, Jeromin A, Blennow K, Lönneborg A, Wyss-Coray T, Soares H, Bazenet C, Sjögren M, Hu W, Lovestone S, Karsdal MA, et al. The future of blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 115-31. PMID 23850333 DOI: 10.1016/J.Jalz.2013.01.013 |
0.443 |
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| 2014 |
Killick R, Ribe EM, Al-Shawi R, Malik B, Hooper C, Fernandes C, Dobson R, Nolan PM, Lourdusamy A, Furney S, Lin K, Breen G, Wroe R, To AW, Leroy K, ... ... Lovestone S, et al. Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway. Molecular Psychiatry. 19: 88-98. PMID 23164821 DOI: 10.1038/mp.2012.163 |
0.332 |
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| 2014 |
Baker E, Patel H, Lunnon K, Proitsi P, Powell J, Hodges A, Kloszewska I, Meccoci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, Khondoker M, Newhouse S, Dobson R. The use of polygenic risk scores for predicting rate of cognitive decline in Alzheimer's disease F1000research. 5. DOI: 10.7490/F1000Research.1097147.1 |
0.389 |
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| 2014 |
Voyle N, Keohane A, Newhouse S, Lunnon K, Simmons A, Westman E, Soininen H, Kloszewska I, Meccoci P, Tsolaki M, Vellas B, Lovestone S, Hodges A, Dobson R, Kiddle S. Blood based gene expression markers of Alzheimer's Disease phenotypes: a pathway based approach F1000research. 5. DOI: 10.7490/F1000Research.1096799.1 |
0.387 |
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| 2014 |
Visser PJ, Streffer JR, Lovestone S. A European Medical Information Framework For Alzheimer'S Disease (Emif-Ad) Alzheimers & Dementia. 11: 799. DOI: 10.1016/J.Jalz.2015.07.022 |
0.435 |
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| 2014 |
Ashton NJ, Kiddle SJ, Thurfjell L, Graf J, Ward M, Baird AL, Hye A, Dobson RJ, Torres A, Zhang Z, Covin A, Tan-Hehir C, Baker D, Bazenet C, Macaulay L, ... Lovestone S, et al. P1-166: DISTINCT BLOOD PROTEIN MARKERS ARE ASSOCIATED WITH BRAIN REGIONS OF EARLY AMYLOID DEPOSITION IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P360-P361. DOI: 10.1016/J.Jalz.2014.05.404 |
0.434 |
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| 2014 |
Westwood S, Leoni E, Lynham S, Khondoker M, Kiddle S, Sattlecker M, Ashton NJ, Fuertes RS, Hye A, Bazenet C, Ward M, Thambisetty M, Lovestone S. P1-008: BLOOD-BASED BIOMARKERS OF ALZHEIMER'S DISEASE PATHOLOGY AND COGNITIVE DECLINE IN NON-DEMENTED ELDERLY Alzheimer's & Dementia. 10: P307-P307. DOI: 10.1016/j.jalz.2014.05.243 |
0.327 |
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| 2014 |
Visser PJ, Streffer JR, Lovestone S. P4-046: A EUROPEAN MEDICAL INFORMATION FRAMEWORK FOR ALZHEIMER'S DISEASE (EMIF-AD) Alzheimer's & Dementia. 10: P799-P799. DOI: 10.1016/j.jalz.2014.05.1560 |
0.329 |
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| 2014 |
Ward MA, Hyman B, Scherzer C, Trisini-Lipsanopoulos A, Ivinson AJ, Lößner C, Farztdinov V, Lovestone S, Pike I. P3-126: EXPLORATION OF PLASMA BIOMARKERS FOR ALZHEIMER'S DISEASE USING ISOTOPIC TANDEM MASS TAGS AND A COMBINED DIRECTED/DATA-DEPENDENT ACQUISITION NLC-MS/MS METHOD Alzheimer's & Dementia. 10: P674-P674. DOI: 10.1016/J.Jalz.2014.05.1215 |
0.324 |
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| 2014 |
Liang H, Russell C, Chung R, Bazenet C, Hye A, Lovestone S, Pike I, Ward MA. Structural Elucidation Of The Glycosylation Profiles Of Human Plasma Clusterin In Alzheimer'S Disease Patients Alzheimers & Dementia. 10: 672. DOI: 10.1016/J.Jalz.2014.05.1209 |
0.372 |
|
| 2014 |
Bazenet C, Ashton N, Kiddle S, Thurfjell L, Graf J, Ward M, Baird A, Hye A, Dobson R, Torres A, Zhang Z, Covin A, Tan-Hehir C, Baker D, Lovestone S. Novel Candidate Blood Proteome Markers Of Alzheimer'S Disease Brain Amyloid Burden: A Multiplex Tmt-Lc/Ms-Ms Discovery Approach Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.1202 |
0.352 |
|
| 2014 |
Baird AL, Ashton N, Westwood S, Ward M, Bazenet C, Thambisetty M, Scheltens P, Teunissen C, Lovestone S. P3-108: DISCOVERY AND VALIDATION OF PLASMA BIOMARKERS RELATING TO CSF MEASURES OF ALZHEIMER'S DISEASE PATHOLOGY Alzheimer's & Dementia. 10: P668-P668. DOI: 10.1016/J.Jalz.2014.05.1197 |
0.36 |
|
| 2014 |
Hall A, Muñoz-Ruiz MÁ, Mattila J, Koikkalainen J, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Visser PJ, Lötjönen J, Soininen H. Comparing Conversion From Mild Cognitive Impairment To Alzheimer'S Disease In Different Cohorts Alzheimers & Dementia. 10: 36. DOI: 10.1016/J.Jalz.2014.05.069 |
0.349 |
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| 2014 |
Ashton NJ, Hye A, Baird A, Torres A, Covin A, Bazenet C, Tan-Hehir C, Baker D, MaCaulay L, Thurfjell L, Ward M, Dobson R, Lovestone S, Kiddle S, Zhang Z. Distinct Blood Protein Markers Are Associated With Global And Regional Brain Beta-Amyloid Deposition In Alzheimer'S Disease Alzheimers & Dementia. 10: 283. DOI: 10.1016/J.Jalz.2014.04.463 |
0.409 |
|
| 2014 |
Lunnon K, Smith R, Hannon E, Volta M, Troakes C, Haroutunian V, Katsel P, Al-Sarraj S, Lovestone S, Schalkwyk L, Mill J. Cross-Tissue Methylomic Profiling In Alzheimer'S Disease Alzheimers & Dementia. 10: 215. DOI: 10.1016/J.Jalz.2014.04.288 |
0.399 |
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| 2014 |
Soares HD, Lovestone S. Biomarker utility in Alzheimer's disease clinical trials Drug Discovery Today: Therapeutic Strategies. DOI: 10.1016/J.Ddstr.2013.09.002 |
0.427 |
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| 2013 |
Paajanen T, Hänninen T, Aitken A, Hallikainen M, Westman E, Wahlund LO, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Spenger C, Lovestone S, Simmons A, Soininen H, et al. CERAD Neuropsychological Total Scores Reflect Cortical Thinning in Prodromal Alzheimer's Disease. Dementia and Geriatric Cognitive Disorders Extra. 3: 446-58. PMID 24516412 DOI: 10.1159/000356725 |
0.448 |
|
| 2013 |
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Lovestone S, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802 |
0.428 |
|
| 2013 |
Mullins D, Daly E, Simmons A, Beacher F, Foy CM, Lovestone S, Hallahan B, Murphy KC, Murphy DG. Dementia in Down's syndrome: an MRI comparison with Alzheimer's disease in the general population. Journal of Neurodevelopmental Disorders. 5: 19. PMID 23962297 DOI: 10.1186/1866-1955-5-19 |
0.428 |
|
| 2013 |
Noble W, Hanger DP, Miller CC, Lovestone S. The importance of tau phosphorylation for neurodegenerative diseases. Frontiers in Neurology. 4: 83. PMID 23847585 DOI: 10.3389/Fneur.2013.00083 |
0.441 |
|
| 2013 |
Leung R, Proitsi P, Simmons A, Lunnon K, Güntert A, Kronenberg D, Pritchard M, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Soininen H, Wahlund LO, Lovestone S. Inflammatory proteins in plasma are associated with severity of Alzheimer's disease. Plos One. 8: e64971. PMID 23762274 DOI: 10.1371/Journal.Pone.0064971 |
0.462 |
|
| 2013 |
Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Lovestone S, et al. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular Psychiatry. 18: 781-7. PMID 23608917 DOI: 10.1038/Mp.2013.24 |
0.36 |
|
| 2013 |
Velayudhan L, Pritchard M, Powell JF, Proitsi P, Lovestone S. Smell identification function as a severity and progression marker in Alzheimer's disease. International Psychogeriatrics / Ipa. 25: 1157-66. PMID 23597130 DOI: 10.1017/S1041610213000446 |
0.425 |
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| 2013 |
Aguilar C, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, Lovestone S, Spenger C, Simmons A, Wahlund LO. Different multivariate techniques for automated classification of MRI data in Alzheimer's disease and mild cognitive impairment. Psychiatry Research. 212: 89-98. PMID 23541334 DOI: 10.1016/J.Pscychresns.2012.11.005 |
0.43 |
|
| 2013 |
Mangialasche F, Westman E, Kivipelto M, Muehlboeck JS, Cecchetti R, Baglioni M, Tarducci R, Gobbi G, Floridi P, Soininen H, Kłoszewska I, Tsolaki M, Vellas B, Spenger C, Lovestone S, et al. Classification and prediction of clinical diagnosis of Alzheimer's disease based on MRI and plasma measures of α-/γ-tocotrienols and γ-tocopherol. Journal of Internal Medicine. 273: 602-21. PMID 23343471 DOI: 10.1111/Joim.12037 |
0.416 |
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| 2013 |
Spulber G, Simmons A, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Lovestone S, Wahlund LO, Westman E. An MRI-based index to measure the severity of Alzheimer's disease-like structural pattern in subjects with mild cognitive impairment. Journal of Internal Medicine. 273: 396-409. PMID 23278858 DOI: 10.1111/Joim.12028 |
0.443 |
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| 2013 |
Killick R, Hughes TR, Morgan BP, Lovestone S. Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH. Neuroscience Letters. 533: 96-9. PMID 23153828 DOI: 10.1016/J.Neulet.2012.11.008 |
0.468 |
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| 2013 |
Velayudhan L, Proitsi P, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Hodges A, Powell J, Lovestone S, Simmons A. Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 755-66. PMID 23047370 DOI: 10.3233/Jad-2012-121408 |
0.443 |
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| 2013 |
Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Geschwind D, ... Lovestone S, et al. A blood gene expression marker of early Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 737-53. PMID 23042217 DOI: 10.3233/Jad-2012-121363 |
0.464 |
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| 2013 |
Thambisetty M, Beason-Held LL, An Y, Kraut M, Nalls M, Hernandez DG, Singleton AB, Zonderman AB, Ferrucci L, Lovestone S, Resnick SM. Alzheimer risk variant CLU and brain function during aging. Biological Psychiatry. 73: 399-405. PMID 22795969 DOI: 10.1016/J.Biopsych.2012.05.026 |
0.409 |
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| 2013 |
Lovestone S. Trait, state, and mechanism: looking back, looking forward, and understanding why. Journal of Alzheimer's Disease : Jad. 33: S23-33. PMID 22710918 DOI: 10.3233/Jad-2012-129014 |
0.309 |
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| 2013 |
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 45: 712-712. DOI: 10.1038/Ng0613-712A |
0.396 |
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| 2013 |
Killick R, Hughes TR, Morgan BP, Lovestone S. Corrigendum to Deletion of Crry, the murine ortholog of the sporadic Alzheimer's disease risk gene CR1, impacts tau phosphorylation and brain CFH [Neurosci. Lett. 533 (2013) 96-99] Neuroscience Letters. 545: 144. DOI: 10.1016/J.Neulet.2013.05.004 |
0.312 |
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| 2013 |
Baird A, Ashton N, Ward M, Bazenet C, Scheltens P, Teunissen C, Lovestone S. Discovery of peripheral biomarkers of alzheimer'/INS;s disease pathology Journal of the Neurological Sciences. 333: e351. DOI: 10.1016/J.Jns.2013.07.1289 |
0.469 |
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| 2013 |
Westwood S, Lovestone S, Thambisetty M, Ward M. Blood-based biomarkers of Alzheimer's/INS; disease pathology and cognitive decline in non-demented elderly Journal of the Neurological Sciences. 333: e350. DOI: 10.1016/J.Jalz.2014.05.243 |
0.433 |
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| 2013 |
Russell C, Liang H, Hye A, Chung R, Bazenet C, Lovestone S, Pike I, Ward M. Comprehensive analysis of glycosylation patterns of human plasma clusterin: A putative PTM marker of Alzheimer's disease Alzheimers & Dementia. 9: 237. DOI: 10.1016/J.Jalz.2013.05.455 |
0.421 |
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| 2013 |
Mistrellides C, Lunnon K, Sattlecker M, Schalkwyk L, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A. MicroRNA biomarkers in Alzheimer's disease Alzheimers & Dementia. 9: 224. DOI: 10.1016/J.Jalz.2013.05.422 |
0.453 |
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| 2013 |
Mikula M, Proitsi P, Sattlecker M, O'Sullivan M, Simmons A, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, Hodges A. Association of magnetic resonance imaging white matter lesions and cognitive decline in Alzheimer's disease Alzheimers & Dementia. 9: 701. DOI: 10.1016/J.Jalz.2013.04.386 |
0.349 |
|
| 2013 |
del Ser T, Lovestone S, Boada-Rovira M, Dubois B, Hüll M, Rinne J, León T. O4-05-02: A phase II randomized, double-blind, parallel group, 26-week study of GSK-3 inhibitor tideglusib in Alzheimer's disease (ARGO trial) Alzheimer's & Dementia. 9: P689-P690. DOI: 10.1016/J.Jalz.2013.04.359 |
0.327 |
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| 2012 |
Greco I, Day N, Riddoch-Contreras J, Reed J, Soininen H, KÅ‚oszewska I, Tsolaki M, Vellas B, Spenger C, Mecocci P, Wahlund LO, Simmons A, Barnes J, Lovestone S. Alzheimer's disease biomarker discovery using in silico literature mining and clinical validation. Journal of Translational Medicine. 10: 217. PMID 23113945 DOI: 10.1186/1479-5876-10-217 |
0.454 |
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| 2012 |
Kiddle SJ, Thambisetty M, Simmons A, Riddoch-Contreras J, Hye A, Westman E, Pike I, Ward M, Johnston C, Lupton MK, Lunnon K, Soininen H, Kloszewska I, Tsolaki M, Vellas B, ... ... Lovestone S, et al. Plasma based markers of [11C] PiB-PET brain amyloid burden. Plos One. 7: e44260. PMID 23028511 DOI: 10.1371/Journal.Pone.0044260 |
0.441 |
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| 2012 |
Bazenet C, Lovestone S. Plasma biomarkers for Alzheimer's disease: much needed but tough to find. Biomarkers in Medicine. 6: 441-54. PMID 22917146 DOI: 10.2217/Bmm.12.48 |
0.442 |
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| 2012 |
Rogers I, Kerr F, Martinez P, Hardy J, Lovestone S, Partridge L. Ageing increases vulnerability to aβ42 toxicity in Drosophila. Plos One. 7: e40569. PMID 22808195 DOI: 10.1371/Journal.Pone.0040569 |
0.313 |
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| 2012 |
Lourdusamy A, Newhouse S, Lunnon K, Proitsi P, Powell J, Hodges A, Nelson SK, Stewart A, Williams S, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, et al. Identification of cis-regulatory variation influencing protein abundance levels in human plasma. Human Molecular Genetics. 21: 3719-26. PMID 22595970 DOI: 10.1093/Hmg/Dds186 |
0.316 |
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| 2012 |
Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Lovestone S, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161 |
0.456 |
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| 2012 |
Lunnon K, Ibrahim Z, Proitsi P, Lourdusamy A, Newhouse S, Sattlecker M, Furney S, Saleem M, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Coppola G, Geschwind D, ... ... Lovestone S, et al. Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood. Journal of Alzheimer's Disease : Jad. 30: 685-710. PMID 22466004 DOI: 10.3233/Jad-2012-111592 |
0.452 |
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| 2012 |
Shi H, Belbin O, Medway C, Brown K, Kalsheker N, Carrasquillo M, Proitsi P, Powell J, Lovestone S, Goate A, Younkin S, Passmore P, Morgan K. Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS). Neurobiology of Aging. 33: 1849.e5-18. PMID 22445811 DOI: 10.1016/J.Neurobiolaging.2012.02.014 |
0.341 |
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| 2012 |
Proitsi P, Lupton MK, Dudbridge F, Tsolaki M, Hamilton G, Daniilidou M, Pritchard M, Lord K, Martin BM, Johnson J, Craig D, Todd S, McGuinness B, Hollingworth P, Harold D, ... ... Lovestone S, et al. Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation. Neurobiology of Aging. 33: 1843.e9-17. PMID 22300950 DOI: 10.1016/J.Neurobiolaging.2011.12.036 |
0.431 |
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| 2012 |
Liu Y, Julkunen V, Paajanen T, Westman E, Wahlund LO, Aitken A, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Spenger C, Lovestone S, Simmons A, Soininen H, et al. Education increases reserve against Alzheimer's disease--evidence from structural MRI analysis. Neuroradiology. 54: 929-38. PMID 22246242 DOI: 10.1007/S00234-012-1005-0 |
0.351 |
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| 2012 |
Mangialasche F, Xu W, Kivipelto M, Costanzi E, Ercolani S, Pigliautile M, Cecchetti R, Baglioni M, Simmons A, Soininen H, Tsolaki M, Kloszewska I, Vellas B, Lovestone S, Mecocci P, et al. Tocopherols and tocotrienols plasma levels are associated with cognitive impairment. Neurobiology of Aging. 33: 2282-90. PMID 22192241 DOI: 10.1016/J.Neurobiolaging.2011.11.019 |
0.38 |
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| 2012 |
Gerrish A, Russo G, Richards A, Moskvina V, Ivanov D, Harold D, Sims R, Abraham R, Hollingworth P, Chapman J, Hamshere M, Pahwa JS, Dowzell K, Williams A, Jones N, ... ... Lovestone S, et al. The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 377-87. PMID 22027014 DOI: 10.3233/Jad-2011-110824 |
0.464 |
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| 2012 |
Hollingworth P, Sweet R, Sims R, Harold D, Russo G, Abraham R, Stretton A, Jones N, Gerrish A, Chapman J, Ivanov D, Moskvina V, Lovestone S, Priotsi P, Lupton M, et al. Genome-wide association study of Alzheimer's disease with psychotic symptoms. Molecular Psychiatry. 17: 1316-27. PMID 22005930 DOI: 10.1016/J.Jalz.2011.05.516 |
0.47 |
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| 2012 |
Velayudhan L, Killick R, Hye A, Kinsey A, Güntert A, Lynham S, Ward M, Leung R, Lourdusamy A, To AW, Powell J, Lovestone S. Plasma transthyretin as a candidate marker for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 28: 369-75. PMID 22002789 DOI: 10.3233/Jad-2011-110611 |
0.471 |
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| 2012 |
Gilleen J, Greenwood K, Archer N, Lovestone S, David AS. The role of premorbid personality and cognitive factors in awareness of illness, memory, and behavioural functioning in Alzheimer's disease. Cognitive Neuropsychiatry. 17: 227-45. PMID 21929281 DOI: 10.1080/13546805.2011.588007 |
0.378 |
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| 2012 |
Aiyaz M, Lupton MK, Proitsi P, Powell JF, Lovestone S. Complement activation as a biomarker for Alzheimer's disease. Immunobiology. 217: 204-15. PMID 21856034 DOI: 10.1016/J.Imbio.2011.07.023 |
0.465 |
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| 2012 |
Thambisetty M, An Y, Kinsey A, Koka D, Saleem M, Güntert A, Kraut M, Ferrucci L, Davatzikos C, Lovestone S, Resnick SM. Plasma clusterin concentration is associated with longitudinal brain atrophy in mild cognitive impairment. Neuroimage. 59: 212-7. PMID 21824521 DOI: 10.1016/J.Neuroimage.2011.07.056 |
0.406 |
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| 2012 |
Whitehead D, Tunnard C, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas B, Spenger C, KÅ‚oszewska I, Soininen H, Cromb D, Lovestone S, Simmons A. Frontotemporal atrophy associated with paranoid delusions in women with Alzheimer's disease. International Psychogeriatrics / Ipa. 24: 99-107. PMID 21740613 DOI: 10.1017/S1041610211000974 |
0.422 |
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| 2012 |
Proitsi P, Lupton MK, Reeves SJ, Hamilton G, Archer N, Martin BM, Iyegbe C, Hollingworth P, Lawlor B, Gill M, Brayne C, Rubinsztein DC, Owen MJ, Williams J, Lovestone S, et al. Association of serotonin and dopamine gene pathways with behavioral subphenotypes in dementia. Neurobiology of Aging. 33: 791-803. PMID 20685009 DOI: 10.1016/J.Neurobiolaging.2010.06.011 |
0.302 |
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| 2012 |
Sofola O, Kerr F, Rogers I, Killick R, Augustin H, Gandy C, Allen MJ, Hardy J, Lovestone S, Partridge L. Correction: Inhibition of GSK-3 Ameliorates Aβ Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease Plos Genetics. 8. DOI: 10.1371/annotation/baa8a2a9-130b-4959-b6fb-6f786fd02826 |
0.328 |
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| 2012 |
Aiyaz M, Hakobyan S, Harris C, Stretton A, Baird A, Ashton N, Hye A, Riddoch-Contreras J, Settlecker M, Dobson R, Morgan P, Lovestone S. P2-059: Identification of blood-based complement biomarkers in Alzheimer's disease Alzheimer's & Dementia. 8: P283-P283. DOI: 10.1016/J.Jalz.2012.05.763 |
0.432 |
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| 2012 |
Riddoch-Contreras J, Hye A, Baird A, Ashton N, Sattlecker M, Dobson R, Ward M, Pike I, Lovestone S. Predicting the progression of Alzheimer's disease by plasma-based biomarkers Alzheimers & Dementia. 8: 282. DOI: 10.1016/J.Jalz.2012.05.758 |
0.423 |
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| 2012 |
Kerr F, Rogers I, Martinez P, Hardy J, Lovestone S, Partridge L. Ageing increases vulnerability to Aβ42 toxicity in drosophila Alzheimers & Dementia. 8: 202. DOI: 10.1016/J.Jalz.2012.05.554 |
0.314 |
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| 2012 |
Newhouse S, Proitsi P, Sattlecker M, Lunnon K, Ibrahim Z, Johnston C, Lourdusamy A, Lupton M, Powell J, Khondoker M, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, ... Lovestone S, et al. Genome-wide association analysis identifies common variants associated with measures of disease progression in patients with Alzheimer's disease Alzheimers & Dementia. 8: 101. DOI: 10.1016/J.Jalz.2012.05.253 |
0.487 |
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| 2012 |
Hye A, Riddoch-Contreras J, Baird A, Ashton N, Sattlecker M, Dobson R, Ward M, Pike I, Lovestone S. P2-408: Classification of Alzheimer's disease using multiplex plasma-based biomarkers Alzheimer's & Dementia. 8: P407-P407. DOI: 10.1016/J.Jalz.2012.05.2033 |
0.425 |
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| 2012 |
Hye A, Riddoch-Contreras J, Baird A, Ashton N, Sattlecker M, Dobson R, Ward M, Pike I, Thambisetty M, Lovestone S. S1-02-01: Multiplexed analysis of plasma in Alzheimer's disease Alzheimer's & Dementia. 8: P78-P79. DOI: 10.1016/J.Jalz.2012.05.186 |
0.41 |
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| 2012 |
Hakobyan S, Aiyaz M, Stretton A, Sattlecker M, Dobson R, Harris C, Morgan P, Lovestone S. Hunting for biomarkers: The complement system in Alzheimer's disease Immunobiology. 217: 1175. DOI: 10.1016/J.Imbio.2012.08.133 |
0.467 |
|
| 2011 |
Thambisetty M, Simmons A, Hye A, Campbell J, Westman E, Zhang Y, Wahlund LO, Kinsey A, Causevic M, Killick R, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, ... ... Lovestone S, et al. Plasma biomarkers of brain atrophy in Alzheimer's disease. Plos One. 6: e28527. PMID 22205954 DOI: 10.1371/Journal.Pone.0028527 |
0.455 |
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| 2011 |
Hardy J, Guerreiro R, Lovestone S. Clusterin as an Alzheimer biomarker. Archives of Neurology. 68: 1459-60. PMID 22084130 DOI: 10.1001/Archneurol.2011.1000 |
0.439 |
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| 2011 |
Furney SJ, Kronenberg D, Simmons A, Güntert A, Dobson RJ, Proitsi P, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lovestone S. Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease--cytokines and MRI measures together predict disease progression. Journal of Alzheimer's Disease : Jad. 26: 395-405. PMID 21971479 DOI: 10.3233/Jad-2011-0044 |
0.428 |
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| 2011 |
Westman E, Wahlund LO, Foy C, Poppe M, Cooper A, Murphy D, Spenger C, Lovestone S, Simmons A. Magnetic resonance imaging and magnetic resonance spectroscopy for detection of early Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 26: 307-19. PMID 21971470 DOI: 10.3233/Jad-2011-0028 |
0.386 |
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| 2011 |
Sims R, Dwyer S, Harold D, Gerrish A, Hollingworth P, Chapman J, Jones N, Abraham R, Ivanov D, Pahwa JS, Moskvina V, Dowzell K, Thomas C, Stretton A, Lovestone S, et al. No evidence that extended tracts of homozygosity are associated with Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 764-71. PMID 21812096 DOI: 10.1002/Ajmg.B.31216 |
0.451 |
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| 2011 |
Westman E, Cavallin L, Muehlboeck JS, Zhang Y, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Spenger C, Lovestone S, Simmons A, Wahlund LO. Sensitivity and specificity of medial temporal lobe visual ratings and multivariate regional MRI classification in Alzheimer's disease. Plos One. 6: e22506. PMID 21811624 DOI: 10.1371/Journal.Pone.0022506 |
0.396 |
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| 2011 |
Westman E, Simmons A, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Weiner MW, Lovestone S, Spenger C, Wahlund LO. AddNeuroMed and ADNI: similar patterns of Alzheimer's atrophy and automated MRI classification accuracy in Europe and North America. Neuroimage. 58: 818-28. PMID 21763442 DOI: 10.1016/J.Neuroimage.2011.06.065 |
0.43 |
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| 2011 |
Hopkins PC, Sáinz-Fuertes R, Lovestone S. The impact of a novel apolipoprotein E and amyloid-β protein precursor-interacting protein on the production of amyloid-β. Journal of Alzheimer's Disease : Jad. 26: 239-53. PMID 21593558 DOI: 10.3233/Jad-2011-102115 |
0.423 |
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| 2011 |
Lamar M, Foy CM, Beacher F, Daly E, Poppe M, Archer N, Prasher V, Murphy KC, Morris RG, Simmons A, Lovestone S, Murphy DG. Down syndrome with and without dementia: an in vivo proton Magnetic Resonance Spectroscopy study with implications for Alzheimer's disease. Neuroimage. 57: 63-8. PMID 21504795 DOI: 10.1016/J.Neuroimage.2011.03.073 |
0.412 |
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| 2011 |
Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, ... ... Lovestone S, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nature Genetics. 43: 429-35. PMID 21460840 DOI: 10.1038/Ng.803 |
0.34 |
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| 2011 |
Lupton MK, Proitsi P, Danillidou M, Tsolaki M, Hamilton G, Wroe R, Pritchard M, Lord K, Martin BM, Kloszewska I, Soininen H, Mecocci P, Vellas B, Harold D, Hollingworth P, ... Lovestone S, et al. Deep sequencing of the Nicastrin gene in pooled DNA, the identification of genetic variants that affect risk of Alzheimer's disease. Plos One. 6: e17298. PMID 21364883 DOI: 10.1371/Journal.Pone.0017298 |
0.46 |
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| 2011 |
To AW, Ribe EM, Chuang TT, Schroeder JE, Lovestone S. The ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated mice. Plos One. 6: e16991. PMID 21347323 DOI: 10.1371/Journal.Pone.0016991 |
0.412 |
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| 2011 |
Foy CM, Daly EM, Glover A, O'Gorman R, Simmons A, Murphy DG, Lovestone S. Hippocampal proton MR spectroscopy in early Alzheimer's disease and mild cognitive impairment. Brain Topography. 24: 316-22. PMID 21298332 DOI: 10.1007/S10548-011-0170-5 |
0.45 |
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| 2011 |
Costafreda SG, Dinov ID, Tu Z, Shi Y, Liu CY, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Wahlund LO, Spenger C, Toga AW, Lovestone S, Simmons A. Automated hippocampal shape analysis predicts the onset of dementia in mild cognitive impairment. Neuroimage. 56: 212-9. PMID 21272654 DOI: 10.1016/J.Neuroimage.2011.01.050 |
0.433 |
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| 2011 |
Simmons A, Westman E, Muehlboeck S, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Wahlund LO, Soininen H, Lovestone S, Evans A, Spenger C. The AddNeuroMed framework for multi-centre MRI assessment of Alzheimer's disease: experience from the first 24 months. International Journal of Geriatric Psychiatry. 26: 75-82. PMID 21157852 DOI: 10.1002/Gps.2491 |
0.423 |
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| 2011 |
Hampel H, Wilcock G, Andrieu S, Aisen P, Blennow K, Broich K, Carrillo M, Fox NC, Frisoni GB, Isaac M, Lovestone S, Nordberg A, Prvulovic D, Sampaio C, Scheltens P, et al. Biomarkers for Alzheimer's disease therapeutic trials. Progress in Neurobiology. 95: 579-93. PMID 21130138 DOI: 10.1016/J.Pneurobio.2010.11.005 |
0.426 |
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| 2011 |
Furney SJ, Simmons A, Breen G, Pedroso I, Lunnon K, Proitsi P, Hodges A, Powell J, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, ... ... Lovestone S, et al. Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease. Molecular Psychiatry. 16: 1130-8. PMID 21116278 DOI: 10.1038/Mp.2010.123 |
0.422 |
|
| 2011 |
Tunnard C, Whitehead D, Hurt C, Wahlund LO, Mecocci P, Tsolaki M, Vellas B, Spenger C, KÅ‚oszewska I, Soininen H, Lovestone S, Simmons A. Apathy and cortical atrophy in Alzheimer's disease. International Journal of Geriatric Psychiatry. 26: 741-8. PMID 20872914 DOI: 10.1002/Gps.2603 |
0.386 |
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| 2011 |
Westman E, Simmons A, Zhang Y, Muehlboeck JS, Tunnard C, Liu Y, Collins L, Evans A, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Soininen H, Lovestone S, Spenger C, et al. Multivariate analysis of MRI data for Alzheimer's disease, mild cognitive impairment and healthy controls. Neuroimage. 54: 1178-87. PMID 20800095 DOI: 10.1016/J.Neuroimage.2010.08.044 |
0.43 |
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| 2011 |
Kerr F, Augustin H, Piper MD, Gandy C, Allen MJ, Lovestone S, Partridge L. Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging. 32: 1977-89. PMID 19969390 DOI: 10.1016/J.Neurobiolaging.2009.10.015 |
0.466 |
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| 2011 |
Liu Y, Paajanen T, Zhang Y, Westman E, Wahlund LO, Simmons A, Tunnard C, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, Lovestone S, et al. Combination analysis of neuropsychological tests and structural MRI measures in differentiating AD, MCI and control groups--the AddNeuroMed study. Neurobiology of Aging. 32: 1198-206. PMID 19683363 DOI: 10.1016/J.Neurobiolaging.2009.07.008 |
0.402 |
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| 2011 |
Proitsi P, Hamilton G, Tsolaki M, Lupton M, Daniilidou M, Hollingworth P, Archer N, Foy C, Stylios F, McGuinness B, Todd S, Lawlor B, Gill M, Brayne C, Rubinsztein DC, ... ... Lovestone S, et al. A Multiple Indicators Multiple Causes (MIMIC) model of Behavioural and Psychological Symptoms in Dementia (BPSD). Neurobiology of Aging. 32: 434-42. PMID 19386383 DOI: 10.1016/J.Neurobiolaging.2009.03.005 |
0.368 |
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| 2011 |
Furney SJ, Kronenberg D, Simmons A, Güntert A, Dobson RJ, Proitsi P, Wahlund LO, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Spenger C, Lovestone S. Combinatorial markers of mild cognitive impairment conversion to Alzheimer's disease-cytokines and MRI measures together predict disease progression Advances in Alzheimer's Disease. 2: 789-799. DOI: 10.3233/978-1-60750-793-2-789 |
0.315 |
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| 2011 |
Eskildsen SF, Westman E, Gwadry-Sridhar F, Julin P, Sjögren N, Muehlboeck S, Wahlund L-, Tsolaki M, Soininen H, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Simmons A, Spenger C. Cortical thinning patterns in Alzheimer's patients and subjects with mild cognitive impairment from the AddNeuroMed study Neurodegenerative Diseases. 8. DOI: 10.1159/000327701 |
0.356 |
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| 2011 |
Velayudhan L, Pritchard M, Lovestone S. P01-498 - Smell identification test as a progression marker in Alzheimer's disease European Psychiatry. 26: 502-502. DOI: 10.1016/S0924-9338(11)72209-X |
0.452 |
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| 2011 |
Brunton S, Ginestet C, Lovestone S, Muehlboeck S, Simmons A. P4-351: Longitudinal volume changes of the hippocampus, parahippocampus and entorhinal cortex improve the prediction of conversion from MCI to Alzheimer's disease Alzheimer's & Dementia. 7: e34-e35. DOI: 10.1016/J.Jalz.2011.09.097 |
0.403 |
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| 2011 |
Proitsi P, Lupton M, Tsolaki M, Daniilidou M, Soininen H, Vellas B, Kloszewska I, Mecocci P, Passmore P, Williams J, Lovestone S. P4-337: A genotype risk score based on Type 2 diabetes risk factors is associated with lower risk for Alzheimer's disease in APOE e4 carriers Alzheimer's & Dementia. 7: e28-e29. DOI: 10.1016/J.Jalz.2011.09.082 |
0.336 |
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| 2011 |
Westman E, Muehlboeck J, Lovestone S, Simmons A. P4-298: Combining MRI and CSF measures for classification of Alzheimer's disease and prediction of mild cognitive impairment conversion Alzheimer's & Dementia. 7: e16-e16. DOI: 10.1016/J.Jalz.2011.09.043 |
0.419 |
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| 2011 |
O'Brien D, Byers H, Campbell J, Dayon L, Guntert A, Leung R, Kuhn K, Lovestone S, Ward M. AD TMT-SRM Assay - delivering simultaneous quantitation of 9 key plasma proteins in clinical cohorts relevant to AD research Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.971 |
0.398 |
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| 2011 |
Velayudhan L, Pritchard M, Lovestone S. P2-077: Smell identification test as a progression marker in Alzheimer's disease Alzheimer's & Dementia. 7: S331-S332. DOI: 10.1016/j.jalz.2011.05.967 |
0.326 |
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| 2011 |
Velayudhan L, Pritchard M, Lovestone S. Smell identification test as a progression marker in Alzheimer's disease European Psychiatry. 26: 502-502. DOI: 10.1016/J.Jalz.2011.05.967 |
0.441 |
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| 2011 |
Paajanen T, Hanninen T, Tunnard C, Hallikainen M, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H. CERAD memory composite score is an accurate neuropsychological predictor of progression to Alzheimer's disease: AddNeuroMed study Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.737 |
0.383 |
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| 2011 |
Spenger C, Eskildsen SF, Sjogren N, Julin P, Westman E, Wahlund L, Gwadry-Sridhar F, Muehlboeck S, Lovestone S, Simmons A. Cortical atrophy rates in Alzheimer's disease and mild cognitive impairment from the ADNI study Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.632 |
0.413 |
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| 2011 |
Thambisetty M, Beason-Held L, Kraut M, Nalls M, Hernandez D, Singleton A, Ferrucci L, Lovestone S, Resnick S. P1-267: Alzheimer Risk Variant Clusterin (CLU) and Brain Function During Aging Alzheimer's & Dementia. 7: S196-S196. DOI: 10.1016/J.Jalz.2011.05.547 |
0.337 |
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| 2011 |
Ward MA, Soininen H, O'Brien D, Lovestone S, Hallikainen M, Herukka S, Schofield E, Campbell J, Dayon L. P1-125: Evaluation of CSF cystatin C, beta-2-microglobulin, and VGF as diagnostic biomarkers of Alzheimer's disease using SRM Alzheimer's & Dementia. 7: S150-S151. DOI: 10.1016/J.Jalz.2011.05.405 |
0.397 |
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| 2010 |
Jones L, Holmans PA, Hamshere ML, Harold D, Moskvina V, Ivanov D, Pocklington A, Abraham R, Hollingworth P, Sims R, Gerrish A, Pahwa JS, Jones N, Stretton A, Morgan AR, ... Lovestone S, et al. Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease. Plos One. 5: e13950. PMID 21085570 DOI: 10.1371/Journal.Pone.0013950 |
0.389 |
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| 2010 |
Paajanen T, Hänninen T, Tunnard C, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H, Addneuromed Consortium. CERAD neuropsychological battery total score in multinational mild cognitive impairment and control populations: the AddNeuroMed study. Journal of Alzheimer's Disease : Jad. 22: 1089-97. PMID 20930314 DOI: 10.3233/Jad-2010-100459 |
0.401 |
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| 2010 |
Thambisetty M, Tripaldi R, Riddoch-Contreras J, Hye A, An Y, Campbell J, Sojkova J, Kinsey A, Lynham S, Zhou Y, Ferrucci L, Wong DF, Lovestone S, Resnick SM. Proteome-based plasma markers of brain amyloid-β deposition in non-demented older individuals. Journal of Alzheimer's Disease : Jad. 22: 1099-109. PMID 20930274 DOI: 10.3233/Jad-2010-101350 |
0.418 |
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| 2010 |
Cruchaga C, Kauwe JS, Mayo K, Spiegel N, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MM, Williams J, Lovestone S, Peskind ER, Li G, et al. SNPs associated with cerebrospinal fluid phospho-tau levels influence rate of decline in Alzheimer's disease. Plos Genetics. 6: e1001101. PMID 20862329 DOI: 10.1371/Journal.Pgen.1001101 |
0.472 |
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| 2010 |
Liu Y, Paajanen T, Westman E, Zhang Y, Wahlund LO, Simmons A, Tunnard C, Sobow T, Proitsi P, Powell J, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, ... ... Lovestone S, et al. APOE ε2 allele is associated with larger regional cortical thicknesses and volumes. Dementia and Geriatric Cognitive Disorders. 30: 229-37. PMID 20847553 DOI: 10.1159/000320136 |
0.376 |
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| 2010 |
Westman E, Wahlund LO, Foy C, Poppe M, Cooper A, Murphy D, Spenger C, Lovestone S, Simmons A. Combining MRI and MRS to distinguish between Alzheimer's disease and healthy controls. Journal of Alzheimer's Disease : Jad. 22: 171-81. PMID 20847449 DOI: 10.3233/Jad-2010-100168 |
0.391 |
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| 2010 |
Caušević M, Farooq U, Lovestone S, Killick R. β-Amyloid precursor protein and tau protein levels are differently regulated in human cerebellum compared to brain regions vulnerable to Alzheimer's type neurodegeneration. Neuroscience Letters. 485: 162-6. PMID 20826196 DOI: 10.1016/J.Neulet.2010.08.088 |
0.428 |
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| 2010 |
Sofola O, Kerr F, Rogers I, Killick R, Augustin H, Gandy C, Allen MJ, Hardy J, Lovestone S, Partridge L. Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. Plos Genetics. 6: e1001087. PMID 20824130 DOI: 10.1371/Journal.Pgen.1001087 |
0.409 |
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| 2010 |
Liu Y, Paajanen T, Westman E, Wahlund LO, Simmons A, Tunnard C, Sobow T, Proitsi P, Powell J, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, ... Lovestone S, et al. Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study. Journal of Alzheimer's Disease : Jad. 21: 947-66. PMID 20693633 DOI: 10.3233/Jad-2010-100201 |
0.393 |
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| 2010 |
Thambisetty M, Simmons A, Velayudhan L, Hye A, Campbell J, Zhang Y, Wahlund LO, Westman E, Kinsey A, Güntert A, Proitsi P, Powell J, Causevic M, Killick R, Lunnon K, ... ... Lovestone S, et al. Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease. Archives of General Psychiatry. 67: 739-48. PMID 20603455 DOI: 10.1001/Archgenpsychiatry.2010.78 |
0.488 |
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| 2010 |
Güntert A, Campbell J, Saleem M, O'Brien DP, Thompson AJ, Byers HL, Ward MA, Lovestone S. Plasma gelsolin is decreased and correlates with rate of decline in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 21: 585-96. PMID 20571216 DOI: 10.3233/Jad-2010-100279 |
0.475 |
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| 2010 |
Liu Y, Paajanen T, Zhang Y, Westman E, Wahlund LO, Simmons A, Tunnard C, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Evans A, Spenger C, Lovestone S, et al. Analysis of regional MRI volumes and thicknesses as predictors of conversion from mild cognitive impairment to Alzheimer's disease. Neurobiology of Aging. 31: 1375-85. PMID 20447732 DOI: 10.1016/J.Neurobiolaging.2010.01.022 |
0.41 |
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| 2010 |
Thambisetty M, Lovestone S. Blood-based biomarkers of Alzheimer's disease: challenging but feasible. Biomarkers in Medicine. 4: 65-79. PMID 20387303 DOI: 10.2217/Bmm.09.84 |
0.397 |
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| 2010 |
Cocks G, Wilde JI, Graham SJ, Bousgouni V, Virley D, Lovestone S, Richardson J. The thiazolidinedione pioglitazone increases cholesterol biosynthetic gene expression in primary cortical neurons by a PPARgamma-independent mechanism. Journal of Alzheimer's Disease : Jad. 19: 631-46. PMID 20110608 DOI: 10.3233/Jad-2010-1266 |
0.351 |
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| 2010 |
Velayudhan L, Poppe M, Archer N, Proitsi P, Brown RG, Lovestone S. Risk of developing dementia in people with diabetes and mild cognitive impairment. The British Journal of Psychiatry : the Journal of Mental Science. 196: 36-40. PMID 20044657 DOI: 10.1192/Bjp.Bp.109.067942 |
0.338 |
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| 2010 |
Kauwe JS, Bertelsen S, Mayo K, Cruchaga C, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Morris JC, Goate AM. Suggestive synergy between genetic variants in TF and HFE as risk factors for Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 955-9. PMID 20029940 DOI: 10.1002/Ajmg.B.31053 |
0.42 |
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| 2010 |
Hurt CS, Banerjee S, Tunnard C, Whitehead DL, Tsolaki M, Mecocci P, Kloszewska I, Soininen H, Vellas B, Lovestone S. Insight, cognition and quality of life in Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 81: 331-6. PMID 19828481 DOI: 10.1136/Jnnp.2009.184598 |
0.421 |
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| 2010 |
Beacher F, Daly E, Simmons A, Prasher V, Morris R, Robinson C, Lovestone S, Murphy K, Murphy DG. Brain anatomy and ageing in non-demented adults with Down's syndrome: an in vivo MRI study. Psychological Medicine. 40: 611-9. PMID 19671216 DOI: 10.1017/S0033291709990985 |
0.331 |
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| 2010 |
Nicholas H, Moran P, Foy C, Brown RG, Lovestone S, Bryant S, Boothby H. Are abnormal premorbid personality traits associated with Alzheimer's disease? - A case-control study. International Journal of Geriatric Psychiatry. 25: 345-51. PMID 19582776 DOI: 10.1002/Gps.2345 |
0.396 |
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| 2010 |
Lupton MK, Stahl D, Archer N, Foy C, Poppe M, Lovestone S, Hollingworth P, Williams J, Owen MJ, Dowzell K, Abraham R, Sims R, Brayne C, Rubinsztein D, Gill M, et al. Education, occupation and retirement age effects on the age of onset of Alzheimer's disease. International Journal of Geriatric Psychiatry. 25: 30-6. PMID 19459177 DOI: 10.1002/Gps.2294 |
0.363 |
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| 2010 |
Hooper C, Soliman R, Lovestone S, Killick R. p63α and γ Induce TAU Phosphorylation in Cultured Mammalian Cells Journal of Experimental Neuroscience. 4: JEN.S6295. DOI: 10.4137/Jen.S6295 |
0.334 |
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| 2010 |
Lunnon KS, Sivapalan H, Vincent A, Proitsi P, Pritchard M, Martin B, Lord K, Tunnard C, Leung R, Dunlop N, Lovestone S, Hodges A. Small Chronic Alterations in Gene Expression and Circulating Blood Cells in Alzheimer's Disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.172 |
0.379 |
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| 2010 |
Eskildsen SF, Westman E, Gwadry-Sridhar F, Julin P, Sjögren N, Muehlboeck S, Wahlund L, Tsolaki M, Soininen H, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Simmons A, Spenger C. Cortical atrophy rates in Alzheimer's patients and subjects with mild cognitive impairment from the AddNeuroMed data collection Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.972 |
0.358 |
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| 2010 |
Westman E, Wahlund L, Foy C, Poppe M, Cooper A, Murphy D, Spenger C, Lovestone S, Simmons A. P1-379: 1H-MRS a valuable complement to MRI in the early diagnosis of Alzheimer's disease Alzheimer's & Dementia. 6: S283-S283. DOI: 10.1016/J.Jalz.2010.05.933 |
0.396 |
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| 2010 |
Kerr FK, Gandy C, Lovestone S, Partridge L. P1-109: Oxidative damage and the neuropathology of Alzheimer's disease in Drosophila Alzheimer's & Dementia. 6: S206-S206. DOI: 10.1016/J.Jalz.2010.05.658 |
0.4 |
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| 2010 |
Cruchaga C, Kauwe JS, Mayo K, Bertelsen S, Nowotny P, Shah AR, Abraham R, Hollingworth P, Harold D, Owen MJ, Williams J, Lovestone S, Morris JC, Fagan AM, Holtzman DM, et al. SNPs associated with CSF tau levels modify rate of progression in Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.612 |
0.363 |
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| 2010 |
Thambisetty M, An Y, Guentert A, Kinsey A, Kraut MA, Davatzikos C, Ferrucci L, Lovestone S, Resnick SM. O2-05-01: Clusterin, an amyloid chaperone protein in plasma is associated with longitudinal brain atrophy in mild cognitive impairment Alzheimer's & Dementia. 6: S106-S107. DOI: 10.1016/J.Jalz.2010.05.330 |
0.337 |
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| 2010 |
Lovestone S, Simmons A. F1-02-03: Combinatorial markers of MCI conversion: Cytokines and MRI measures together predict disease progression Alzheimer's & Dementia. 6: S62-S62. DOI: 10.1016/J.Jalz.2010.05.178 |
0.312 |
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| 2010 |
O'Brien DP, Guentert A, Campbell J, Kuhn K, Ward MA, Byers HL, Lovestone S. P3-259: Development and implementation of a TMT-SRM assay for the qualification of candidate biomarkers of Alzheimer's disease Alzheimer's & Dementia. 6: S527-S527. DOI: 10.1016/J.Jalz.2010.05.1759 |
0.44 |
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| 2010 |
Velayudhan L, Hye A, Kinsey A, Lynham S, Foy C, Dunlop N, Tunnard C, Leung R, Lovestone S. P3-243: Plasma transthyretin as a candidate marker of cognitive decline and severity in Alzheimer's disease Alzheimer's & Dementia. 6: S522-S523. DOI: 10.1016/J.Jalz.2010.05.1742 |
0.424 |
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| 2010 |
Leung R, Simmons A, Guntert A, Kronenberg D, Furney SJ, Pritchard M, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Soininen H, Spenger C, Wahlund L, Lovestone S. P3-221: Plasma inflammatory markers correlate with severity in Alzheimer's disease Alzheimer's & Dementia. 6: S515-S515. DOI: 10.1016/J.Jalz.2010.05.1720 |
0.401 |
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| 2010 |
Hodges AK, Wong G, Lunnon K, Lovestone S. P3-202: Plasma microRNA: A new source of biomarker for Alzheimer's disease Alzheimer's & Dementia. 6: S510-S510. DOI: 10.1016/J.Jalz.2010.05.1701 |
0.406 |
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| 2010 |
Westman E, Simmons A, Muehlboeck J-, Gwadry-Sridhar F, Eskildsen SF, Julin P, Sjögren N, Collins DL, Evans A, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Weiner M, ... Lovestone S, et al. Combining Two Large MRI Data Sets (AddNeuroMed and ADNI) Using Multivariate Data Analysis to Distinguish between Patients with Alzheimer's Disease and Healthy Controls Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.152 |
0.376 |
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| 2010 |
Husain MO, Nicholas H, Moran P, Foy C, Brown R, Lovestone S, Bryant S, Boothby H. Are abnormal premorbid personality traits a marker for Alzheimer's disease? A case-control study Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1502 |
0.402 |
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| 2010 |
Ribe EM, Killick R, Al-Shawi R, Malik B, Hooper C, Fernandes C, To AW, Lin K, Furney S, Anderton B, Simons JP, Lovestone S. P2-319: An Aβ transcription signature Alzheimer's & Dementia. 6: S407-S407. DOI: 10.1016/J.Jalz.2010.05.1370 |
0.317 |
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| 2010 |
Spulber G, Westman E, Reiman EM, Chen K, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Simmons A, Lovestone S, Wahlund L, Soininen H. IC-P-089: Can Three Months MRI Volumetric Parameters Help the Prediction of Progression from MCI to Alzheimer's Disease? Results from the Addneuromed Study Alzheimer's & Dementia. 6: S36-S37. DOI: 10.1016/J.Jalz.2010.05.103 |
0.391 |
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| 2010 |
Simmons A, Westman E, Zhang Y, Muehlboeck J-, Tunnard C, Collins DL, Evans A, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Spenger C, Wahlund L. Multivariate Analysis of MRI Data to Discriminate between Groups and Predict Conversion in Alzheimer's Disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.101 |
0.34 |
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| 2009 |
Simmons A, Westman E, Muehlboeck S, Mecocci P, Vellas B, Tsolaki M, KÅ‚oszewska I, Wahlund LO, Soininen H, Lovestone S, Evans A, Spenger C. MRI measures of Alzheimer's disease and the AddNeuroMed study. Annals of the New York Academy of Sciences. 1180: 47-55. PMID 19906260 DOI: 10.1111/J.1749-6632.2009.05063.X |
0.4 |
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| 2009 |
Lovestone S, Francis P, Kloszewska I, Mecocci P, Simmons A, Soininen H, Spenger C, Tsolaki M, Vellas B, Wahlund LO, Ward M. AddNeuroMed--the European collaboration for the discovery of novel biomarkers for Alzheimer's disease. Annals of the New York Academy of Sciences. 1180: 36-46. PMID 19906259 DOI: 10.1111/J.1749-6632.2009.05064.X |
0.442 |
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| 2009 |
Lovestone S. Biomarkers in brain disease. Preface. Annals of the New York Academy of Sciences. 1180: vii. PMID 19906254 DOI: 10.1111/J.1749-6632.2009.05107.X |
0.33 |
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| 2009 |
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genetics. 41: 1088-93. PMID 19734902 DOI: 10.1038/Ng.440 |
0.386 |
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| 2009 |
Velayudhan L, Lovestone S. Smell identification test as a treatment response marker in patients with Alzheimer disease receiving donepezil. Journal of Clinical Psychopharmacology. 29: 387-90. PMID 19593181 DOI: 10.1097/Jcp.0B013E3181Aba5A5 |
0.384 |
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| 2009 |
Killick R, Scales G, Leroy K, Causevic M, Hooper C, Irvine EE, Choudhury AI, Drinkwater L, Kerr F, Al-Qassab H, Stephenson J, Yilmaz Z, Giese KP, Brion JP, Withers DJ, ... Lovestone S, et al. Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice. Biochemical and Biophysical Research Communications. 386: 257-62. PMID 19523444 DOI: 10.1016/J.Bbrc.2009.06.032 |
0.375 |
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| 2009 |
Sims R, Hollingworth P, Moskvina V, Dowzell K, O'Donovan MC, Powell J, Lovestone S, Brayne C, Rubinsztein D, Owen MJ, Williams J, Abraham R. Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease. Neuroscience Letters. 461: 54-9. PMID 19477230 DOI: 10.1016/J.Neulet.2009.05.051 |
0.406 |
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| 2009 |
Lovestone S, Thambisetty M. Biomarkers for Alzheimer's disease trials--biomarkers for what? A discussion paper. The Journal of Nutrition, Health & Aging. 13: 334-6. PMID 19300870 DOI: 10.1007/S12603-009-0033-X |
0.388 |
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| 2009 |
Greenberg N, Grassano A, Thambisetty M, Lovestone S, Legido-Quigley C. A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease. Electrophoresis. 30: 1235-9. PMID 19288586 DOI: 10.1002/Elps.200800589 |
0.481 |
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| 2009 |
Archer N, Brown RG, Reeves S, Nicholas H, Boothby H, Lovestone S. Midlife Neuroticism and the age of onset of Alzheimer's disease. Psychological Medicine. 39: 665-73. PMID 18694539 DOI: 10.1017/S003329170800408X |
0.416 |
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| 2009 |
Beacher F, Daly E, Simmons A, Prasher V, Morris R, Robinson C, Lovestone S, Murphy K, Murphy DG. Alzheimer's disease and Down's syndrome: an in vivo MRI study. Psychological Medicine. 39: 675-84. PMID 18667098 DOI: 10.1017/S0033291708004054 |
0.436 |
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| 2009 |
Morgan AR, Hollingworth P, Abraham R, Lovestone S, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Association analysis of dynamin-binding protein (DNMBP) on chromosome 10q with late onset Alzheimer's disease in a large caucasian UK sample. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 61-4. PMID 18452187 DOI: 10.1002/Ajmg.B.30768 |
0.329 |
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| 2009 |
Proitsi P, Lupton M, Reeves S, Hamilton G, Archer N, Martin B, hollingworth P, Lawlord B, Gill M, Owen MJ, Williams J, Lovestone S, Powell J. Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). Nature Precedings. DOI: 10.1038/Npre.2009.3896.1 |
0.307 |
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| 2009 |
Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Williams A, Jones N, Thomas C, Stretton A, Morgan AR, Lovestone S, et al. Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease Nature Genetics. 41: 1156-1156. DOI: 10.1038/Ng1009-1156D |
0.396 |
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| 2009 |
Mullins D, Lamar M, Daly E, Simmons A, Murphy K, Lovestone S, Murphy D. Dementia in Alzheimer’s Disease: A Comparison of MRI and 1H-MRS Findings Between Alzheimer’s Disease and Mild Cognitive Impairment European Psychiatry. 24: 1-1. DOI: 10.1016/S0924-9338(09)70929-0 |
0.441 |
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| 2009 |
Mullins D, Daly E, Simmons A, Johnston P, Murphy K, Lovestone S, Murphy D. Comparison of Brain Morphology in Alzheimer’s Dementia in the General Population and Demented Subjects with Down’s Syndrome European Psychiatry. 24: 1-1. DOI: 10.1016/S0924-9338(09)70928-9 |
0.427 |
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| 2009 |
Simmons A, Westman E, Zhang Y, Muehlboeck S, Liu Y, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Evans A, Collins L, Lovestone S, Spenger C, Wahlund L. P4-295: Multivariate Data Analysis Of Regional MRI Volumes and Cortical Thickness Measures To Distinguish Between Alzheimer's Disease, Mild Cognitive Impairment And Healthy Controls Alzheimer's & Dementia. 5: e16-e16. DOI: 10.1016/J.Jalz.2009.07.075 |
0.403 |
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| 2009 |
Thambisetty M, Tripaldi R, Campbell J, Sojkova J, Kinsey A, Hye A, Lynham S, Zhou Y, Ferrucci L, Wong D, Lovestone S, Resnick S. Proteome-based identification of plasma biomarkers predicting in vivo brain amyloid burden during normal aging Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.449 |
0.324 |
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| 2009 |
Harold D, Hollingworth P, Hamshere M, Holmans P, Abraham R, Sims R, Gerrish A, Lovestone S, Brayne C, Gill M, Lawlor B, Passmore P, Nothen M, Maier W, Livingston G, et al. P4-133: Genome-wide association study of age at onset of Alzheimer's disease Alzheimer's & Dementia. 5: P471-P471. DOI: 10.1016/J.Jalz.2009.04.801 |
0.409 |
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| 2009 |
Gerrish A, Harold D, Sims R, Abraham R, Hollingworth P, Hamshere M, Lovestone S, Brayne C, Gill M, Lawlor B, Passmore P, Nothen M, Mayer W, Livingston G, Bass N, et al. P4-124: An examination of previously reported Alzheimer candidate genes within a large genome-wide association dataset Alzheimer's & Dementia. 5: P468-P468. DOI: 10.1016/J.Jalz.2009.04.792 |
0.347 |
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| 2009 |
Hollingworth P, Sims R, Abraham R, Harold D, Gerrish A, Hamshere M, Lovestone S, Brayne C, Gill M, Lawlor B, Passmore P, Nothen M, Mayer W, Livingston G, Bass N, et al. P4-121: Genome-wide association study of Alzheimer's with psychotic symptoms Alzheimer's & Dementia. 5: P467-P467. DOI: 10.1016/J.Jalz.2009.04.789 |
0.341 |
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| 2009 |
Sims R, Hollingworth P, Abraham R, Harold D, Holmans P, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Craig D, Passmore P, Nöthen M, Mayer W, et al. P4-120: Investigating psychosis candidate genes in Alzheimer's disease with psychosis using genome-wide association studies Alzheimer's & Dementia. 5: P466-P467. DOI: 10.1016/J.Jalz.2009.04.788 |
0.414 |
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| 2009 |
Lovestone S. Alzheimer's Disease and Other Dementias (Including Pseudodementias) Lishman's Organic Psychiatry: a Textbook of Neuropsychiatry, Fourth Edition. 543-615. DOI: 10.1002/9781444316803.ch9 |
0.376 |
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| 2008 |
Hooper C, Lovestone S, Sainz-Fuertes R. Alzheimer's Disease, Diagnosis and the Need for Biomarkers. Biomarker Insights. 3: 317-323. PMID 19578515 DOI: 10.4137/Bmi.S682 |
0.487 |
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| 2008 |
Thambisetty M, Hye A, Foy C, Daly E, Glover A, Cooper A, Simmons A, Murphy D, Lovestone S. Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease. Journal of Neurology. 255: 1712-20. PMID 19156487 DOI: 10.1007/S00415-008-0006-8 |
0.466 |
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| 2008 |
Winblad B, Frisoni GB, Frolich L, Johannsen P, Johansson G, Kehoe P, Lovestone S, Olde-Rikkert M, Reynish E, Visser PJ, Vellas B. Editorial: EADC (European Alzheimer Disease Consortium) recommendations for future Alzheimer disease research in Europe. The Journal of Nutrition, Health & Aging. 12: 683-4. PMID 19043641 DOI: 10.1007/Bf03028614 |
0.444 |
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| 2008 |
Kwok JB, Loy CT, Hamilton G, Lau E, Hallupp M, Williams J, Owen MJ, Broe GA, Tang N, Lam L, Powell JF, Lovestone S, Schofield PR. Glycogen synthase kinase-3beta and tau genes interact in Alzheimer's disease. Annals of Neurology. 64: 446-54. PMID 18991351 DOI: 10.1002/Ana.21476 |
0.418 |
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| 2008 |
Macdonald A, Briggs K, Poppe M, Higgins A, Velayudhan L, Lovestone S. A feasibility and tolerability study of lithium in Alzheimer's disease. International Journal of Geriatric Psychiatry. 23: 704-11. PMID 18181229 DOI: 10.1002/Gps.1964 |
0.371 |
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| 2008 |
Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, Hollingworth P, Moskvina V, Brayne C, Rubinsztein DC, Lynch A, Lawlor B, Gill M, O'Donovan M, Powell J, ... Lovestone S, et al. Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 727-31. PMID 18163421 DOI: 10.1002/Ajmg.B.30670 |
0.333 |
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| 2008 |
Hooper C, Killick R, Lovestone S. The GSK3 hypothesis of Alzheimer's disease. Journal of Neurochemistry. 104: 1433-9. PMID 18088381 DOI: 10.1111/J.1471-4159.2007.05194.X |
0.478 |
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| 2008 |
Li Y, Grupe A, Rowland C, Holmans P, Segurado R, Abraham R, Jones L, Catanese J, Ross D, Mayo K, Martinez M, Hollingworth P, Goate A, Cairns NJ, Racette BA, ... ... Lovestone S, et al. Evidence that common variation in NEDD9 is associated with susceptibility to late-onset Alzheimer's and Parkinson's disease. Human Molecular Genetics. 17: 759-67. PMID 18063669 DOI: 10.1093/Hmg/Ddm348 |
0.39 |
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| 2008 |
Li H, Wetten S, Li L, St Jean PL, Upmanyu R, Surh L, Hosford D, Barnes MR, Briley JD, Borrie M, Coletta N, Delisle R, Dhalla D, Ehm MG, Feldman HH, ... ... Lovestone S, et al. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Archives of Neurology. 65: 45-53. PMID 17998437 DOI: 10.1001/Archneurol.2007.3 |
0.433 |
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| 2008 |
Li Y, Rowland C, Catanese J, Morris J, Lovestone S, O'Donovan MC, Goate A, Owen M, Williams J, Grupe A. SORL1 variants and risk of late-onset Alzheimer's disease. Neurobiology of Disease. 29: 293-6. PMID 17949987 DOI: 10.1016/J.Nbd.2007.09.001 |
0.361 |
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| 2008 |
O'Brien DP, Byers HL, Kuhn K, Ward MA, Schulz-Knappe P, Lovestone S. P1-361: The development of mass spectrometry-based assays for the monitoring of candidate markers of Alzheimer's disease Alzheimer's & Dementia. 4: T324-T325. DOI: 10.1016/J.Jalz.2008.05.943 |
0.405 |
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| 2008 |
Day NC, Arnold BC, Hodkinson CJ, Lovestone S, Barnes JC. P1-357: Integration, search and analysis tools for multidisciplinary clinical and preclinical data to facilitate identification of Alzheimer's disease biomarkers Alzheimer's & Dementia. 4: T323-T323. DOI: 10.1016/J.Jalz.2008.05.939 |
0.413 |
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| 2008 |
Simmons A, Westman E, Segerdahl T, Bengtsson JO, Wahlund L, Zhang Y, Soininen H, Vellas B, Mecocci P, Kloszewska I, Evans A, Muehlboeck S, Julin P, Lovestone S, Spenger C. P1-291: Early magnetic resonance imaging results from the addneuromed Alzheimer's disease study Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.881 |
0.366 |
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| 2008 |
Thambisetty M, Simmons A, Hye A, O'Brien D, Campbell J, Kinsey A, Causevic M, Killick R, Broadstock M, Prinz T, Tunnard C, Dunlop N, Foy C, Spenger C, Ward M, ... ... Lovestone S, et al. O3-02-05: Proteomic identification of plasma biomarkers for hippocampal atrophy in Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.418 |
0.4 |
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| 2008 |
Lovestone S. S3-04-06: Deletion of IRS2 reduces amyloid deposition, inhibits GSK-3 and rescues behavioral deficits in APP transgenic mice Alzheimer's & Dementia. 4: T155-T156. DOI: 10.1016/J.Jalz.2008.05.397 |
0.301 |
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| 2008 |
Williams J, Abraham R, Morgan A, Sims R, Hollingworth P, O'Donovan M, Owen M, Holmans P, Nikolov I, Moskvina V, Lovestone S, Rubinsztein D, Brayne C, Gill M, Lawlor B, et al. O2-06-01: A powerful, genome-wide association scan for susceptibility genes for late-onset Alzheimer's disease Alzheimer's & Dementia. 4: T143-T143. DOI: 10.1016/J.Jalz.2008.05.349 |
0.372 |
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| 2008 |
Spenger C, Westman E, Segerdahl T, Bengtsson J, Wahlund L, Soininen H, Kononen M, Tsolaki M, Mauredaki P, Mecocci P, Tarducci R, Kloszewska I, Sobow T, Vellas B, Payoux P, ... ... Lovestone S, et al. O1-02-08: The innomed/addneuromed framework for multicenter MRI assessment of longitudinal changes in Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.227 |
0.373 |
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| 2008 |
Sims R, Hollingworth P, Morgan A, Dowzell K, Stretton A, Jones L, Norton N, Williams H, Georgieva L, Moskvina V, Nikolov I, Hamshere M, Holmans P, Lovestone S, Brayne C, et al. P3-265: Testing for association between Alzheimer's disease with psychosis and variants identified as influencing risk of schizophrenia Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1833 |
0.368 |
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| 2008 |
Morgan AR, Abraham R, Hollingworth P, Lovestone S, Brayne C, Rubinsztein DC, O'Donovan M, Owen MJ, Williams J. P3-245: Association analysis of tau and progranulin with late-onset Alzheimer's disease in a large caucasian U.K. sample Alzheimer's & Dementia. 4: T592-T593. DOI: 10.1016/J.Jalz.2008.05.1812 |
0.419 |
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| 2008 |
Abraham R, Georgieva L, Sims R, Morgan A, Hollingworth P, Lovestone S, Brayne C, Cichon S, O'Donovan M, Williams J, Owen M, Kirov G. P3-196: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1762 |
0.395 |
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| 2008 |
Kinsey AM, Thambisetty M, Hye A, Causevic M, Killick R, Broadstock M, Prinz T, Tunnard C, Dunlop N, Simmons A, Spenger C, Ward M, Francis P, Lovestone S. P3-022: Correlation of plasma biomarkers with clinical measures of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1585 |
0.337 |
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| 2008 |
Hollingworth P, Dowzell K, Williams A, Keates S, Abraham R, Morgan A, Foy C, Archer N, Powell J, Lovestone S, O'Donavan M, Owen MJ, Williams J. P3-016: The APOE-ϵ4 allele does not affect rate of cognitive and functional decline in late-onset Alzheimer's disease (AD): Findings from the U.K. Medical Research Council (MRC) genetic resource for AD Alzheimer's & Dementia. 4: T521-T521. DOI: 10.1016/J.Jalz.2008.05.1579 |
0.457 |
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| 2008 |
Vellas B, Winblad B, Frisoni G, Frölich L, Johannsen P, Johansson G, Kehoe P, Lovestone S, Olde-Rikkert M, Reynish E, Visser PJ. EADC (European Alzheimer Disease Consortium) recommendations for future Alzheimer disease research in Europe Sinapse. 8: 3-4. |
0.335 |
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| 2007 |
Ikin AF, Causevic M, Pedrini S, Benson LS, Buxbaum JD, Suzuki T, Lovestone S, Higashiyama S, Mustelin T, Burgoyne RD, Gandy S. Evidence against roles for phorbol binding protein Munc13-1, ADAM adaptor Eve-1, or vesicle trafficking phosphoproteins Munc18 or NSF as phospho-state-sensitive modulators of phorbol/PKC-activated Alzheimer APP ectodomain shedding. Molecular Neurodegeneration. 2: 23. PMID 18067682 DOI: 10.1186/1750-1326-2-23 |
0.331 |
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| 2007 |
Hamilton G, Proitsi P, Williams J, O'Donovan M, Owen M, Powell J, Lovestone S. Complement factor H Y402H polymorphism is not associated with late-onset Alzheimer's disease. Neuromolecular Medicine. 9: 331-4. PMID 17999207 DOI: 10.1007/S12017-007-8013-Y |
0.46 |
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| 2007 |
Hamshere ML, Holmans PA, Avramopoulos D, Bassett SS, Blacker D, Bertram L, Wiener H, Rochberg N, Tanzi RE, Myers A, Wavrant-De Vrièze F, Go R, Fallin D, Lovestone S, Hardy J, et al. Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease. Human Molecular Genetics. 16: 2703-12. PMID 17725986 DOI: 10.1093/Hmg/Ddm224 |
0.306 |
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| 2007 |
Foy CM, Nicholas H, Hollingworth P, Boothby H, Willams J, Brown RG, Al-Sarraj S, Lovestone S. Diagnosing Alzheimer's disease--non-clinicians and computerised algorithms together are as accurate as the best clinical practice. International Journal of Geriatric Psychiatry. 22: 1154-63. PMID 17530621 DOI: 10.1002/Gps.1810 |
0.4 |
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| 2007 |
Hollingworth P, Hamshere ML, Holmans PA, O'Donovan MC, Sims R, Powell J, Lovestone S, Myers A, DeVrieze FW, Hardy J, Goate A, Owen M, Williams J. Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 841-8. PMID 17492769 DOI: 10.1002/Ajmg.B.30515 |
0.445 |
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| 2007 |
Hamilton G, Proitsi P, Jehu L, Morgan A, Williams J, O'Donovan MC, Owen MJ, Powell JF, Lovestone S. Candidate gene association study of insulin signaling genes and Alzheimer's disease: evidence for SOS2, PCK1, and PPARgamma as susceptibility loci. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 508-16. PMID 17440948 DOI: 10.1002/Ajmg.B.30503 |
0.392 |
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| 2007 |
Harold D, Jehu L, Turic D, Hollingworth P, Moore P, Summerhayes P, Moskvina V, Foy C, Archer N, Hamilton BA, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Jones L, et al. Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 448-52. PMID 17440933 DOI: 10.1002/Ajmg.B.30456 |
0.431 |
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| 2007 |
Lovestone S, Güntert A, Hye A, Lynham S, Thambisetty M, Ward M. Proteomics of Alzheimer's disease: understanding mechanisms and seeking biomarkers. Expert Review of Proteomics. 4: 227-38. PMID 17425458 DOI: 10.1586/14789450.4.2.227 |
0.41 |
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| 2007 |
Hooper C, Meimaridou E, Tavassoli M, Melino G, Lovestone S, Killick R. p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells. Neuroscience Letters. 418: 34-7. PMID 17399897 DOI: 10.1016/J.Neulet.2007.03.026 |
0.424 |
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| 2007 |
Morgan AR, Turic D, Jehu L, Hamilton G, Hollingworth P, Moskvina V, Jones L, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, O'Donovan MC, Owen MJ, Williams J. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 762-70. PMID 17373700 DOI: 10.1002/Ajmg.B.30509 |
0.333 |
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| 2007 |
Archer N, Brown RG, Reeves SJ, Boothby H, Nicholas H, Foy C, Williams J, Lovestone S. Premorbid personality and behavioral and psychological symptoms in probable Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 15: 202-13. PMID 17322133 DOI: 10.1097/01.Jgp.0000232510.77213.10 |
0.335 |
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| 2007 |
Ellul J, Archer N, Foy CM, Poppe M, Boothby H, Nicholas H, Brown RG, Lovestone S. The effects of commonly prescribed drugs in patients with Alzheimer's disease on the rate of deterioration. Journal of Neurology, Neurosurgery, and Psychiatry. 78: 233-9. PMID 17012333 DOI: 10.1136/Jnnp.2006.104034 |
0.34 |
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| 2006 |
Asuni AA, Hooper C, Reynolds CH, Lovestone S, Anderton BH, Killick R. GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt. The European Journal of Neuroscience. 24: 3387-92. PMID 17229088 DOI: 10.1111/J.1460-9568.2006.05243.X |
0.631 |
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| 2006 |
Hye A, Lynham S, Thambisetty M, Causevic M, Campbell J, Byers HL, Hooper C, Rijsdijk F, Tabrizi SJ, Banner S, Shaw CE, Foy C, Poppe M, Archer N, Hamilton G, ... ... Lovestone S, et al. Proteome-based plasma biomarkers for Alzheimer's disease. Brain : a Journal of Neurology. 129: 3042-50. PMID 17071923 DOI: 10.1093/Brain/Awl279 |
0.444 |
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| 2006 |
Hollingworth P, Hamshere ML, Moskvina V, Dowzell K, Moore PJ, Foy C, Archer N, Lynch A, Lovestone S, Brayne C, Rubinsztein DC, Lawlor B, Gill M, Owen MJ, Williams J. Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease. Journal of the American Geriatrics Society. 54: 1348-54. PMID 16970641 DOI: 10.1111/J.1532-5415.2006.00854.X |
0.369 |
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| 2006 |
Blacker D, Lovestone S. Genetics and dementia nosology. Journal of Geriatric Psychiatry and Neurology. 19: 186-91. PMID 16880361 DOI: 10.1177/0891988706291091 |
0.401 |
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| 2006 |
Li Y, Grupe A, Rowland C, Nowotny P, Kauwe JS, Smemo S, Hinrichs A, Tacey K, Toombs TA, Kwok S, Catanese J, White TJ, Maxwell TJ, Hollingworth P, Abraham R, ... ... Lovestone S, et al. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. Human Molecular Genetics. 15: 2560-8. PMID 16847012 DOI: 10.1093/Hmg/Ddl178 |
0.314 |
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| 2006 |
Kerr F, Rickle A, Nayeem N, Brandner S, Cowburn RF, Lovestone S. PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3. Febs Letters. 580: 3121-8. PMID 16684527 DOI: 10.1016/J.Febslet.2006.04.064 |
0.405 |
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| 2006 |
Archer N, Brown RG, Boothby H, Foy C, Nicholas H, Lovestone S. The NEO-FFI is a reliable measure of premorbid personality in patients with probable Alzheimer's disease. International Journal of Geriatric Psychiatry. 21: 477-84. PMID 16676294 DOI: 10.1002/Gps.1499 |
0.319 |
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| 2006 |
Hooper C, Killick R, Tavassoli M, Melino G, Lovestone S. TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism. Neuroscience Letters. 401: 30-4. PMID 16580132 DOI: 10.1016/J.Neulet.2006.02.082 |
0.371 |
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| 2006 |
Hamilton G, Samedi F, Knight J, Archer N, Foy C, Walter S, Turic D, Jehu L, Moore P, Hollingworth P, O'Donovan MC, Williams J, Owen MJ, Lovestone S, Powell JF. Polymorphisms in the phosphate and tensin homolog gene are not associated with late-onset Alzheimer's disease. Neuroscience Letters. 401: 77-80. PMID 16574322 DOI: 10.1016/J.Neulet.2006.03.021 |
0.357 |
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| 2006 |
Lovestone S. Biomarkers in Alzheimer's disease. The Journal of Nutrition, Health & Aging. 10: 118-22. PMID 16554945 |
0.361 |
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| 2006 |
Smemo S, Nowotny P, Hinrichs AL, Kauwe JS, Cherny S, Erickson K, Myers AJ, Kaleem M, Marlowe L, Gibson AM, Hollingworth P, O'Donovan MC, Morris CM, Holmans P, Lovestone S, et al. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease. Annals of Neurology. 59: 21-6. PMID 16278862 DOI: 10.1002/Ana.20673 |
0.344 |
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| 2006 |
Vos SJ, Bos I, Verhey FR, Engelborghs S, Lleó A, Johannsen P, Freund-Levi Y, Frölich L, Vandenberghe R, Frisoni GB, Blin O, Richardson J, Bordet R, Scheltens P, Ramakers IH, ... ... Lovestone S, et al. P2-270: INCREASED CSF AMYLOID-β 1-38 AND 1-40 CONCENTRATIONS IN INDIVIDUALS WITH MILD COGNITIVE IMPAIRMENT WITH TAU BUT WITHOUT AMYLOID PATHOPHYSIOLOGY Alzheimer's & Dementia. 14: P780-P781. DOI: 10.1016/J.Jalz.2018.06.959 |
0.383 |
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| 2006 |
ten Kate M, Redolfi A, Peira E, Bos I, Vos SJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Wallin A, Molinuevo JL, Tsolaki M, Verhey FR, ... ... Lovestone S, et al. F1-02-03: MRI PREDICTORS OF AMYLOID PATHOLOGY: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY Alzheimer's & Dementia. 14: P202-P204. DOI: 10.1016/J.Jalz.2018.06.2309 |
0.395 |
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| 2006 |
Westwood S, Baird AL, Anand SN, Shi L, Nevado-Holgado AJ, Kormilitzin A, Hye A, Ashton NJ, Morgan A, Touchard S, Morgan P, Bos I, Vos SJ, Vandenberghe R, Scheltens P, ... ... Lovestone S, et al. F1-02-02: DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN AND ALZHEIMER'S DISEASE PROGRESSION Alzheimer's & Dementia. 14: P201-P202. DOI: 10.1016/J.Jalz.2018.06.2308 |
0.43 |
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| 2006 |
Ingala S, ten Kate M, Redolfi A, Wottschel V, Peira E, Bos I, Vos SJ, Scheltens P, Engelborghs S, Frisoni GB, Blin O, Richardson J, Bordet R, Wallin A, Molinuevo JL, ... ... Lovestone S, et al. P2-458: PREDICTING COGNITIVE DECLINE THROUGH STRUCTURAL MRI BIOMARKERS: RESULTS FROM THE EMIF-AD BIOMARKER DISCOVERY STUDY Alzheimer's & Dementia. 14: P895-P896. DOI: 10.1016/J.Jalz.2018.06.1151 |
0.389 |
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| 2006 |
Meimaridou E, Afzal S, Nowotny P, Goate A, Killick R, Lovestone S. P1-413: SORBS1, c-ABL and c-CBL; insulin signalling proteins in Alzheimer's disease Alzheimer's & Dementia. 2: S218-S219. DOI: 10.1016/J.Jalz.2006.05.792 |
0.338 |
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| 2006 |
Abraham R, Morgan AR, Jehu L, Turic D, Hamilton G, Hollingworth P, Moore P, Dowzell K, Holmans P, Moskvina V, Cope N, Powell J, Lovestone S, Brayne C, Rubinsztein DC, et al. P1-335: A powerful association analysis of 496 SNPs in 80 positional candidate genes in a linked region on chromosome 10 for association with late onset Alzheimer's disease Alzheimer's & Dementia. 2: S195-S195. DOI: 10.1016/J.Jalz.2006.05.713 |
0.383 |
|
| 2006 |
Kwok JB, Hallupp M, Loy CT, Harold DH, Williams J, Owen MJ, Lovestone S, Powell J, Broe GA, Schofield PR. P1-332: Glycogen synthase kinase -3 beta polymorphisms interact with Tau haplotypes in Alzheimer's disease Alzheimer's & Dementia. 2: S194-S195. DOI: 10.1016/J.Jalz.2006.05.710 |
0.41 |
|
| 2006 |
Hollingworth P, Hamshere M, Holmans P, Jones L, O'Donavan M, Myers A, Hardy J, Goate A, Lovestone S, Owen M, Williams J. P1-331: Familiality and linkage analysis of behavioral symptoms and age at disease onset in late-onset Alzheimer's disease Alzheimer's & Dementia. 2: S194-S194. DOI: 10.1016/J.Jalz.2006.05.709 |
0.385 |
|
| 2006 |
Sims R, Hollingworth P, Cope N, Jehu L, Morgan A, Moskvina V, Lovestone S, Brayne C, Rubinsztein DC, O’Donovan M, Owen M, Williams J, Abraham R. P1-327: Testing for association between Alzheimer’s disease with psychosis and functional gene candidates Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.705 |
0.331 |
|
| 2006 |
Proitsi P, Hamilton G, Archer N, Foy C, Hollinworth P, Owen M, Williams J, Lovestone S, Powell J. P1-326: Statistical and genetic studies on the psychosis sub-phenotype in Alzheimer’s disease Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.704 |
0.313 |
|
| 2006 |
Williams J, Harold D, Jehu L, Turic D, Hollingworth P, Moskvina V, Brayne C, Rubensztein D, Lovestone S, Powell J, Jones L, O'Donovan M, Owen M. P1-284: Interaction between ADAM12
and SH3MD1
may confer susceptibility to late-onset Alzheimer's disease Alzheimer's & Dementia. 2: S180-S180. DOI: 10.1016/J.Jalz.2006.05.661 |
0.429 |
|
| 2006 |
Lovestone S. PL-05-03: GSK-3 in Alzheimer's disease: Pathogenic kinase, biomarker and therapeutic target or ubiquitous bystander? Alzheimer's & Dementia. 2: S90-S90. DOI: 10.1016/J.Jalz.2006.05.347 |
0.406 |
|
| 2006 |
Cocks GD, Lynham S, Ward M, Richardson J, Lovestone S. P4-388: The effects of NSAIDs and TZDs on the rat cortical proteome: A 2D-ge screen for regulated proteins potentially neuroprotective against AD Alzheimer's & Dementia. 2: S632-S632. DOI: 10.1016/J.Jalz.2006.05.2129 |
0.326 |
|
| 2006 |
Foy C, Beacher F, Daly E, Poppe M, Archer N, Prasher V, Adams C, Luisa Margallo-Lana M, Brown S, Murphy K, Morris R, Simmons A, Murphy D, Lovestone S. P4-139: Dementia in down syndrome. A comparison with Alzheimer's disease Alzheimer's & Dementia. 2: S556-S556. DOI: 10.1016/J.Jalz.2006.05.1878 |
0.446 |
|
| 2006 |
Thambisetty M, Hye A, Foy C, Campbell J, Lynham S, Ward M, Daly E, Poppe M, Archer N, Simmons A, Murphy D, Lovestone S. P3-093: Peripheral biomarkers in Alzheimer's disease: A novel proteomic-neuroimaging approach Alzheimer's & Dementia. 2: S400-S401. DOI: 10.1016/J.Jalz.2006.05.1360 |
0.435 |
|
| 2006 |
Grupe A, Li Y, Rowland C, Abraham R, Hollingworth P, Morgan A, Jehu L, Stone D, Schadt E, Karnoub M, Nowotny P, Tacey K, Catanese J, Sninsky J, Rubinsztein D, ... ... Lovestone S, et al. O2-02-05: Novel candidate genes for late-onset Alzheimer's disease from a large scale association study of 20K functional variants Alzheimer's & Dementia. 2: S33-S33. DOI: 10.1016/J.Jalz.2006.05.115 |
0.366 |
|
| 2005 |
Beacher F, Simmons A, Daly E, Prasher V, Adams C, Margallo-Lana ML, Morris R, Lovestone S, Murphy K, Murphy DG. Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: an in vivo proton magnetic resonance spectroscopy study. Archives of General Psychiatry. 62: 1360-5. PMID 16330724 DOI: 10.1001/Archpsyc.62.12.1360 |
0.34 |
|
| 2005 |
Siyad F, Griffiths J, Janjua F, Jackson E, Rodrigues I, Kerr F, Mackay D, Lovestone S. School students as Drosophila experimenters. Plos Biology. 3: e246. PMID 16000022 DOI: 10.1371/Journal.Pbio.0030246 |
0.315 |
|
| 2005 |
Li Y, Rowland C, Tacey K, Catanese J, Sninsky J, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Goate A, Owen M, Williams J, Grupe A. The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples. Molecular Psychiatry. 10: 809-10. PMID 15970929 DOI: 10.1038/Sj.Mp.4001702 |
0.417 |
|
| 2005 |
Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell T, Holmans P, Hamshere M, Turic D, Jehu L, Hollingworth P, Moore P, Bryden L, Myers A, Doil LM, Tacey KM, ... ... Lovestone S, et al. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 136: 62-8. PMID 15858813 DOI: 10.1002/Ajmg.B.30186 |
0.35 |
|
| 2005 |
Holmes C, Ballard C, Lehmann D, David Smith A, Beaumont H, Day IN, Nadeem Khan M, Lovestone S, McCulley M, Morris CM, Munoz DG, O'Brien K, Russ C, Del Ser T, Warden D. Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 640-3. PMID 15834019 DOI: 10.1136/Jnnp.2004.039321 |
0.409 |
|
| 2005 |
Holmans P, Hamshere M, Hollingworth P, Rice F, Tunstall N, Jones S, Moore P, Wavrant DeVrieze F, Myers A, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, ... ... Lovestone S, et al. Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 135: 24-32. PMID 15729734 DOI: 10.1002/Ajmg.B.30114 |
0.306 |
|
| 2005 |
Li Y, Hollingworth P, Moore P, Foy C, Archer N, Powell J, Nowotny P, Holmans P, O'Donovan M, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Lau K, ... ... Lovestone S, et al. Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease. Human Mutation. 25: 270-7. PMID 15714520 DOI: 10.1002/Humu.20138 |
0.427 |
|
| 2005 |
Cook LJ, Ho LW, Wang L, Terrenoire E, Brayne C, Evans JG, Xuereb J, Cairns NJ, Turic D, Hollingworth P, Moore PJ, Jehu L, Archer N, Walter S, Foy C, ... ... Lovestone S, et al. Candidate gene association studies of genes involved in neuronal cholinergic transmission in Alzheimer's disease suggests choline acetyltransferase as a candidate deserving further study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 132: 5-8. PMID 15690550 DOI: 10.1002/Ajmg.B.30068 |
0.429 |
|
| 2005 |
Hye A, Kerr F, Archer N, Foy C, Poppe M, Brown R, Hamilton G, Powell J, Anderton B, Lovestone S. Glycogen synthase kinase-3 is increased in white cells early in Alzheimer's disease. Neuroscience Letters. 373: 1-4. PMID 15555766 DOI: 10.1016/J.Neulet.2004.10.031 |
0.467 |
|
| 2004 |
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, ... ... Lovestone S, et al. Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family. Proceedings of the National Academy of Sciences of the United States of America. 101: 15688-93. PMID 15507493 DOI: 10.1073/Pnas.0403535101 |
0.417 |
|
| 2004 |
Bruscoli M, Lovestone S. Is MCI really just early dementia? A systematic review of conversion studies. International Psychogeriatrics / Ipa. 16: 129-40. PMID 15318760 DOI: 10.1017/S1041610204000092 |
0.351 |
|
| 2004 |
Li Y, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Lau K, Catanese J, Sninsky J, Nowotny P, Holmans P, Hardy J, Powell J, ... Lovestone S, et al. Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study. Neuroscience Letters. 366: 268-71. PMID 15288432 DOI: 10.1016/J.Neulet.2004.05.047 |
0.356 |
|
| 2004 |
Cervilla J, Prince M, Joels S, Lovestone S, Mann A. Premorbid cognitive testing predicts the onset of dementia and Alzheimer's disease better than and independently of APOE genotype. Journal of Neurology, Neurosurgery, and Psychiatry. 75: 1100-6. PMID 15258208 DOI: 10.1136/Jnnp.2003.028076 |
0.385 |
|
| 2004 |
Busby V, Goossens S, Nowotny P, Hamilton G, Smemo S, Harold D, Turic D, Jehu L, Myers A, Womick M, Woo D, Compton D, Doil LM, Tacey KM, Lau KF, ... ... Lovestone S, et al. Alpha-T-catenin is expressed in human brain and interacts with the Wnt signaling pathway but is not responsible for linkage to chromosome 10 in Alzheimer's disease. Neuromolecular Medicine. 5: 133-46. PMID 15075440 DOI: 10.1385/Nmm:5:2:133 |
0.379 |
|
| 2004 |
Cook LJ, Ho LW, Taylor AE, Brayne C, Evans JG, Xuereb J, Cairns NJ, Pritchard A, Lemmon H, Mann D, St Clair D, Turic D, Hollingworth P, Moore PJ, Jehu L, ... ... Lovestone S, et al. Candidate gene association studies of the alpha 4 (CHRNA4) and beta 2 (CHRNB2) neuronal nicotinic acetylcholine receptor subunit genes in Alzheimer's disease. Neuroscience Letters. 358: 142-6. PMID 15026168 DOI: 10.1016/J.Neulet.2004.01.016 |
0.423 |
|
| 2004 |
Cervilla J, Prince M, Joels S, Russ C, Lovestone S. Genes related to vascular disease (APOE, VLDL-R, DCP-1) and other vascular factors in late-life depression. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 12: 202-10. PMID 15010349 DOI: 10.1097/00019442-200403000-00011 |
0.314 |
|
| 2004 |
Mudher A, Shepherd D, Newman TA, Mildren P, Jukes JP, Squire A, Mears A, Drummond JA, Berg S, MacKay D, Asuni AA, Bhat R, Lovestone S. GSK-3beta inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Molecular Psychiatry. 9: 522-30. PMID 14993907 DOI: 10.1038/Sj.Mp.4001483 |
0.67 |
|
| 2004 |
Myers AJ, Marshall H, Holmans P, Compton D, Crook RJ, Mander AP, Nowotny P, Smemo S, Dunstan M, Jehu L, Wang JC, Hamshere M, Morris JC, Norton J, Chakraventy S, ... ... Lovestone S, et al. Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 124: 29-37. PMID 14681909 DOI: 10.1002/Ajmg.B.20036 |
0.371 |
|
| 2004 |
Jehu L, Dunstan M, Hollingworth P, Moore P, Archer N, Foy C, O'Donovan M, Jones L, Lovestone S, Owen M, Williams J. P4-132 No evidence for association between the APH-1 and PEN-2 components of the gamma secratase complex with late onset Alzheimer's disease Neurobiology of Aging. 25: S513. DOI: 10.1016/S0197-4580(04)81690-7 |
0.415 |
|
| 2004 |
Li Y, Hollingworth P, Moore P, Foy C, Archer N, Nowotny P, Holmans P, Smemo S, Tacey K, Doil L, Luchene Rv, Lau K, Catanese J, Garcia V, Rowland C, ... ... Lovestone S, et al. P4-122 Genetic association of an APP binding protein gene with late onset Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81680-4 |
0.426 |
|
| 2004 |
Doil L, Tacey K, Nowotny P, Luchene Rv, Li Y, Holmans P, Smemo S, Garcia V, Rowland C, Leong D, Gogic G, Cravchik A, Ross D, Lau K, Catanese J, ... ... Lovestone S, et al. P4-110 A systematic scan of chromosome 10 single nucleotide polymorphisms identifies novel candidate genes showing strong association to Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81668-3 |
0.397 |
|
| 2004 |
Dunstan ML, Jehu L, Jones S, Hollingworth P, Moore P, Lovestone S, Nowotny P, Goate A, O'Donovan M, Owen MJ, Jones L, Williams J. P4-106 Evidence for association of the calcium/calmodulin-dependent protein kinase type II gamma isoform (CAMKII γ) with late onset Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81664-6 |
0.371 |
|
| 2004 |
Turic D, Jehu L, Dunstan M, Lloyd B, Peirce T, Jones S, Hollingworth P, Moore P, Hamilton G, Busby LV, Walter S, Archer N, Foy C, Edmondson A, Poppe M, ... ... Lovestone S, et al. P4-090 Evidence of association with late onset Alzheimer's disease on chromosome 10Q Neurobiology of Aging. 25: S500. DOI: 10.1016/S0197-4580(04)81648-8 |
0.368 |
|
| 2004 |
Lau KF, Rowland C, Tacey K, Doil L, Li Y, Luchene Rv, Nowotny P, Smemo S, Garcia V, Lovestone S, Owen M, Williams J, Grupe A, Goate A. P4-067 Genetic association studies of insulin-degrading enzyme (IDE) with late onset Alzheimer's disease (LOAD) - Equivocal results from two large case-control studies Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81625-7 |
0.367 |
|
| 2004 |
Busby VL, Hamilton G, Walter S, Foy C, Archer N, Turic D, Jehu L, Hollingworth P, Moore P, Jones S, Jones L, Williams J, Owen M, Powell J, Lovestone S. P4-059 CDC2 as a candidate for late-onset Alzheimer's disease Neurobiology of Aging. 25: S490. DOI: 10.1016/S0197-4580(04)81617-8 |
0.456 |
|
| 2004 |
Hamilton G, Samadi F, Archer N, Foy C, Walter S, Turic D, Jehu L, Hollingworth P, Jones S, Moore P, Jones L, Williams J, Owen M, Lovestone S, Powell J. P4-058 Searching chromosome 10 for an AD risk factor — Analysis of a positional and biological candidate Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81616-6 |
0.332 |
|
| 2004 |
Li Y, Nowotny P, Holmans P, Smemo S, Kawe K, Tacey K, Doil L, Luchene Rv, Garcia V, Rowland C, Schrodi S, Leong D, Chan J, Lau K, Chang S, ... ... Lovestone S, et al. P4-046 Association of late onset Alzheimer's disease with genetic variation in multiple members of a gene family involved in neuronal apoptosis Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81604-X |
0.383 |
|
| 2004 |
Archer N, Boothby H, Brown R, Foy C, Nicholas H, Poppe M, Shabbir S, Lovestone S. P2-256 The relationship between premorbid personality and the behavioural and psychological symptoms of dementia (BPSD) in patients with Alzheimer's disease (AD) Neurobiology of Aging. 25: S305. DOI: 10.1016/S0197-4580(04)81002-9 |
0.45 |
|
| 2004 |
Mudher AK, Mackay D, Chee F, Shepherd D, Lovestone S. P2-102 Axonal transport and behavioural defects in drosophila expressing wild-type and mutant Tau Neurobiology of Aging. 25: S253. DOI: 10.1016/S0197-4580(04)80849-2 |
0.349 |
|
| 2004 |
Hollingworth P, Hamshere ML, Hill GT, Moore PJ, Ludford RM, Foy C, Archer N, Edmondson A, Proitsi P, Lynch A, Evans I, Hamilton B, Lovestone S, Powell J, Brayne C, et al. P1-014 Principal components analysis of the neuropsychiatric inventory in Alzheimer's disease Neurobiology of Aging. 25: S97. DOI: 10.1016/S0197-4580(04)80328-2 |
0.423 |
|
| 2004 |
Holmans P, Nowotny P, Smemo S, Myers A, Wavrant-DeVrieze F, Hardy J, Lovestone S, Jones L, Williams J, Owen M, Goate A. O3-02-06 Linkage analysis of AD SIB pairs indicates evidence of interaction between genes regulating beta-amyloid degradation Neurobiology of Aging. 25: S55-S56. DOI: 10.1016/S0197-4580(04)80188-X |
0.353 |
|
| 2003 |
Leroy K, Boutajangout A, Richardson J, Octave JN, Lovestone S, Anderton BH, Brion JP. Mutant presenilin 1 proteins induce cell death and reduce tau-dependent processes outgrowth. Neuroscience Letters. 353: 226-30. PMID 14665422 DOI: 10.1016/J.Neulet.2003.09.051 |
0.307 |
|
| 2003 |
Fleminger S, Oliver DL, Lovestone S, Rabe-Hesketh S, Giora A. Head injury as a risk factor for Alzheimer's disease: the evidence 10 years on; a partial replication. Journal of Neurology, Neurosurgery, and Psychiatry. 74: 857-62. PMID 12810767 DOI: 10.1136/Jnnp.74.7.857 |
0.344 |
|
| 2003 |
Harold D, Peirce T, Moskvina V, Myers A, Jones S, Hollingworth P, Moore P, Lovestone S, Powell J, Foy C, Archer N, Walter S, Edmonson A, McIlroy S, Craig D, et al. Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease. Human Genetics. 113: 258-67. PMID 12759818 DOI: 10.1007/S00439-003-0960-2 |
0.438 |
|
| 2003 |
Holmes C, Arranz M, Collier D, Powell J, Lovestone S. Depression in Alzheimer's disease: the effect of serotonin receptor gene variation. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 119: 40-3. PMID 12707936 DOI: 10.1002/Ajmg.B.10068 |
0.333 |
|
| 2003 |
Ljungberg MC, Asuni A, Pearce J, Dayanandan R, März W, Hoffmann MM, Bertrand P, Siest G, Rupniak HT, Anderton BH, Huettinger M, Lovestone S. Apolipoprotein E (apoE) uptake and distribution in mammalian cell lines is dependent upon source of apoE and can be monitored in living cells. Neuroscience Letters. 341: 69-73. PMID 12676346 DOI: 10.1016/S0304-3940(03)00064-8 |
0.654 |
|
| 2003 |
Holmes C, Lovestone S. Long-term cognitive and functional decline in late onset Alzheimer's disease: therapeutic implications. Age and Ageing. 32: 200-4. PMID 12615565 DOI: 10.1093/Ageing/32.2.200 |
0.364 |
|
| 2002 |
Ritchie K, Lovestone S. The dementias. Lancet. 360: 1759-66. PMID 12480441 DOI: 10.1016/S0140-6736(02)11667-9 |
0.309 |
|
| 2002 |
Liolitsa D, Powell J, Lovestone S. Genetic variability in the insulin signalling pathway may contribute to the risk of late onset Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 73: 261-6. PMID 12185156 DOI: 10.1136/Jnnp.73.3.261 |
0.379 |
|
| 2002 |
Lovestone S, Hardy J. Psychotic genes or forgetful ones? Neurology. 59: 11-2. PMID 12105301 DOI: 10.1212/Wnl.59.1.11 |
0.377 |
|
| 2002 |
Lovestone S. Can we afford to develop treatments for dementia? Journal of Neurology, Neurosurgery, and Psychiatry. 72: 685. PMID 12023404 DOI: 10.1136/Jnnp.72.6.685 |
0.447 |
|
| 2002 |
Ljungberg MC, Dayanandan R, Asuni A, Rupniak TH, Anderton BH, Lovestone S. Truncated apoE forms tangle-like structures in a neuronal cell line. Neuroreport. 13: 867-70. PMID 11997703 DOI: 10.1097/00001756-200205070-00026 |
0.695 |
|
| 2002 |
Lovestone S, Philpot M, Connell J, Lantos P, Powell J, Russ C, Anderton B. Genetics, molecular biology, neuropathology and phenotype of frontal lobe dementia: a case history. The British Journal of Psychiatry : the Journal of Mental Science. 180: 455-60. PMID 11983644 DOI: 10.1192/Bjp.180.5.455 |
0.355 |
|
| 2002 |
Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, ... ... Lovestone S, et al. Full genome screen for Alzheimer disease: stage II analysis. American Journal of Medical Genetics. 114: 235-44. PMID 11857588 DOI: 10.1002/Ajmg.10183 |
0.309 |
|
| 2002 |
Holmes C, Lovestone S. The clinical phenotype of familial and sporadic late onset Alzheimer's disease. International Journal of Geriatric Psychiatry. 17: 146-9. PMID 11813277 DOI: 10.1002/Gps.540 |
0.325 |
|
| 2002 |
Russ C, Lovestone S, Powell JF. Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease. Molecular Psychiatry. 7: 104-9. PMID 11803455 DOI: 10.1038/Sj/Mp/4000941 |
0.42 |
|
| 2002 |
Mudher A, Lovestone S. Alzheimer's disease-do tauists and baptists finally shake hands? Trends in Neurosciences. 25: 22-6. PMID 11801334 DOI: 10.1016/S0166-2236(00)02031-2 |
0.471 |
|
| 2002 |
Lovestone S, McLoughlin DM. Protein aggregates and dementia: is there a common toxicity? Journal of Neurology, Neurosurgery, and Psychiatry. 72: 152-61. PMID 11796764 DOI: 10.1136/Jnnp.72.2.152 |
0.421 |
|
| 2001 |
Lovestone S. It takes tau to tangle--the molecular biology of Alzheimer's disease. Transactions of the Medical Society of London. 118: 54-6. PMID 16116806 |
0.35 |
|
| 2001 |
Abraham R, Myers A, Wavrant-DeVrieze F, Hamshere ML, Thomas HV, Marshall H, Compton D, Spurlock G, Turic D, Hoogendoorn B, Kwon JM, Petersen RC, Tangalos E, Norton J, Morris JC, ... ... Lovestone S, et al. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Human Genetics. 109: 646-52. PMID 11810277 DOI: 10.1007/S00439-001-0614-1 |
0.319 |
|
| 2001 |
Mack TG, Dayanandan R, Van Slegtenhorst M, Whone A, Hutton M, Lovestone S, Anderton BH. Tau proteins with frontotemporal dementia-17 mutations have both altered expression levels and phosphorylation profiles in differentiated neuroblastoma cells. Neuroscience. 108: 701-12. PMID 11738505 DOI: 10.1016/S0306-4522(01)00434-1 |
0.372 |
|
| 2001 |
Holmes C, Smith H, Ganderton R, Arranz M, Collier D, Powell J, Lovestone S. Psychosis and aggression in Alzheimer's disease: the effect of dopamine receptor gene variation. Journal of Neurology, Neurosurgery, and Psychiatry. 71: 777-9. PMID 11723200 DOI: 10.1136/Jnnp.71.6.777 |
0.347 |
|
| 2001 |
Russ C, Powell JF, Zhao J, Baker M, Hutton M, Crawford F, Mullan M, Roks G, Cruts M, Lovestone S. The microtubule associated protein Tau gene and Alzheimer's disease--an association study and meta-analysis. Neuroscience Letters. 314: 92-6. PMID 11698154 DOI: 10.1016/S0304-3940(01)02289-3 |
0.471 |
|
| 2001 |
Killick R, Pollard CC, Asuni AA, Mudher AK, Richardson JC, Rupniak HT, Sheppard PW, Varndell IM, Brion JP, Levey AI, Levy OA, Vestling M, Cowburn R, Lovestone S, Anderton BH. Presenilin 1 independently regulates beta-catenin stability and transcriptional activity. The Journal of Biological Chemistry. 276: 48554-61. PMID 11606587 DOI: 10.1074/Jbc.M108332200 |
0.598 |
|
| 2001 |
Brion JP, Anderton BH, Authelet M, Dayanandan R, Leroy K, Lovestone S, Octave JN, Pradier L, Touchet N, Tremp G. Neurofibrillary tangles and tau phosphorylation. Biochemical Society Symposium. 81-8. PMID 11447842 DOI: 10.1042/Bss0670081 |
0.397 |
|
| 2001 |
Anderton BH, Betts J, Blackstock WP, Brion JP, Chapman S, Connell J, Dayanandan R, Gallo JM, Gibb G, Hanger DP, Hutton M, Kardalinou E, Leroy K, Lovestone S, Mack T, et al. Sites of phosphorylation in tau and factors affecting their regulation. Biochemical Society Symposium. 73-80. PMID 11447841 DOI: 10.1042/Bst028A015B |
0.302 |
|
| 2001 |
Lovestone S, Anderton B, Betts J, Dayanandan R, Gibb G, Ljungberg C, Pearce J. Apolipoprotein E gene and Alzheimer's disease: is tau the link? Biochemical Society Symposium. 111-20. PMID 11447827 DOI: 10.1042/Bss0670111 |
0.442 |
|
| 2001 |
Mudher A, Chapman S, Richardson J, Asuni A, Gibb G, Pollard C, Killick R, Iqbal T, Raymond L, Varndell I, Sheppard P, Makoff A, Gower E, Soden PE, Lewis P, ... ... Lovestone S, et al. Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4987-95. PMID 11438574 DOI: 10.1523/Jneurosci.21-14-04987.2001 |
0.654 |
|
| 2001 |
Stewart R, Russ C, Richards M, Brayne C, Lovestone S, Mann A. Apolipoprotein E genotype, vascular risk and early cognitive impairment in an African Caribbean population. Dementia and Geriatric Cognitive Disorders. 12: 251-6. PMID 11351136 DOI: 10.1159/000051267 |
0.33 |
|
| 2001 |
Russ C, Lovestone S, Powell JF. Identification of sequence variants and analysis of the role of the glycogen synthase kinase 3 beta gene and promoter in late onset Alzheimer's disease. Molecular Psychiatry. 6: 320-4. PMID 11326302 DOI: 10.1038/Sj.Mp.4000852 |
0.406 |
|
| 2001 |
Russ C, Lovestone S, Baker M, Pickering-Brown SM, Andersen PM, Furlong R, Mann D, Powell JF. The extended haplotype of the microtubule associated protein tau gene is not associated with Pick's disease. Neuroscience Letters. 299: 156-8. PMID 11166961 DOI: 10.1016/S0304-3940(00)01785-7 |
0.413 |
|
| 2001 |
Liddell MB, Lovestone S, Owen MJ. Genetic risk of Alzheimer's disease: advising relatives. The British Journal of Psychiatry : the Journal of Mental Science. 178: 7-11. PMID 11136203 DOI: 10.1192/Bjp.178.1.7 |
0.441 |
|
| 2001 |
Lovestone S. Dementia, 2nd edition Journal of Neurology, Neurosurgery, and Psychiatry. 70: 821-821. DOI: 10.1136/Jnnp.70.6.821I |
0.334 |
|
| 2000 |
Lovestone S. Fleshing out the amyloid cascade hypothesis: the molecular biology of Alzheimer's disease. Dialogues in Clinical Neuroscience. 2: 101-10. PMID 22033981 |
0.356 |
|
| 2000 |
Forlenza OV, Spink JM, Dayanandan R, Anderton BH, Olesen OF, Lovestone S. Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3beta inhibition and in neurons. Journal of Neural Transmission (Vienna, Austria : 1996). 107: 1201-12. PMID 11129110 DOI: 10.1007/S007020070034 |
0.399 |
|
| 2000 |
Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, ... ... Lovestone S, et al. Susceptibility locus for Alzheimer's disease on chromosome 10. Science (New York, N.Y.). 290: 2304-5. PMID 11125144 DOI: 10.1126/Science.290.5500.2304 |
0.431 |
|
| 2000 |
Gibb GM, Pearce J, Betts JC, Lovestone S, Hoffmann MM, Maerz W, Blackstock WP, Anderton BH. Differential effects of apolipoprotein E isoforms on phosphorylation at specific sites on tau by glycogen synthase kinase-3 beta identified by nano-electrospray mass spectrometry. Febs Letters. 485: 99-103. PMID 11094148 DOI: 10.1016/S0014-5793(00)02196-7 |
0.336 |
|
| 2000 |
Tunstall N, Owen MJ, Williams J, Rice F, Carty S, Lillystone S, Fraser L, Kehoe P, Neill D, Rudrasingham V, Sham P, Lovestone S. Familial influence on variation in age of onset and behavioural phenotype in Alzheimer's disease. The British Journal of Psychiatry : the Journal of Mental Science. 176: 156-9. PMID 10755053 DOI: 10.1192/Bjp.176.2.156 |
0.425 |
|
| 2000 |
Prince M, Lovestone S, Cervilla J, Joels S, Powell J, Russ C, Mann A. The association between APOE and dementia does not seem to be mediated by vascular factors. Neurology. 54: 397-402. PMID 10668701 DOI: 10.1212/Wnl.54.2.397 |
0.415 |
|
| 2000 |
Anderton BH, Dayanandan R, Killick R, Lovestone S. Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease? Molecular Medicine Today. 6: 54-9. PMID 10652477 DOI: 10.1016/S1357-4310(99)01640-8 |
0.444 |
|
| 2000 |
Ljungberg CM, Dayanandan R, Pearce J, Anderton BH, Lovestone S. Monitoring the intracellular fate of apolipoprotein E: Implications for Alzheimer's disease Neurobiology of Aging. 21: 51. DOI: 10.1042/Bst028A037 |
0.427 |
|
| 2000 |
Lovestone S. APOE and Alzheimer's disease – is tau the link? Biochemical Society Transactions. 28: A16-A16. DOI: 10.1042/Bst028A016B |
0.477 |
|
| 2000 |
Liolitsa D, Powell J, Vanhaesebroeck B, Lovestone S. Search for genetic variability of the phosphoinositide 3-kinase (P13-K) in late onset Alzheimer's disease Neurobiology of Aging. 21: 175. DOI: 10.1016/S0197-4580(00)82127-2 |
0.378 |
|
| 1999 |
Tunstall N, Lovestone S. UK Alzheimer's disease genetics consortium. International Journal of Geriatric Psychiatry. 14: 789-91. PMID 10479752 DOI: 10.1002/(Sici)1099-1166(199909)14:9<789::Aid-Gps17>3.0.Co;2-V |
0.429 |
|
| 1999 |
Lovestone S, Davis DR, Webster MT, Kaech S, Brion JP, Matus A, Anderton BH. Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations. Biological Psychiatry. 45: 995-1003. PMID 10386182 DOI: 10.1016/S0006-3223(98)00183-8 |
0.319 |
|
| 1999 |
Rudrasingham V, Wavrant-De Vrièze F, Lambert JC, Chakraverty S, Kehoe P, Crook R, Amouyel P, Wu W, Rice F, Pérez-Tur J, Frigard B, Morris JC, Carty S, Petersen R, Cottel D, ... ... Lovestone S, et al. Alpha-2 macroglobulin gene and Alzheimer disease. Nature Genetics. 22: 17-9; author reply 2. PMID 10319854 DOI: 10.1038/8726 |
0.353 |
|
| 1999 |
Wavrant-DeVrièze F, Rudrasingham V, Lambert JC, Chakraverty S, Kehoe P, Crook R, Amouyel P, Wu W, Holmans P, Rice F, Pérez-Tur J, Frigard B, Morris JC, Carty S, Cottel D, ... ... Lovestone S, et al. No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease. Neuroscience Letters. 262: 137-9. PMID 10203250 DOI: 10.1016/S0304-3940(99)00035-X |
0.404 |
|
| 1999 |
Lovestone S. Early diagnosis and the clinical genetics of Alzheimer's disease. Journal of Neurology. 246: 69-72. PMID 10195399 DOI: 10.1007/S004150050310 |
0.414 |
|
| 1999 |
Cervilla JA, Russ C, Holmes C, Aitchison K, Smith CA, Powell J, Lovestone S. CYP2D6 polymorphisms in Alzheimer's disease, with and without extrapyramidal signs, showing no apolipoprotein E epsilon 4 effect modification. Biological Psychiatry. 45: 426-9. PMID 10071712 DOI: 10.1016/S0006-3223(98)00060-2 |
0.45 |
|
| 1999 |
Kehoe P, Wavrant-De Vrieze F, Crook R, Wu WS, Holmans P, Fenton I, Spurlock G, Norton N, Williams H, Williams N, Lovestone S, Perez-Tur J, Hutton M, Chartier-Harlin MC, Shears S, et al. A full genome scan for late onset Alzheimer's disease. Human Molecular Genetics. 8: 237-45. PMID 9931331 DOI: 10.1093/Hmg/8.2.237 |
0.413 |
|
| 1999 |
Kehoe PG, Russ C, McIlory S, Williams H, Holmans P, Holmes C, Liolitsa D, Vahidassr D, Powell J, McGleenon B, Liddell M, Plomin R, Dynan K, Williams N, Neal J, ... ... Lovestone S, et al. Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. Nature Genetics. 21: 71-2. PMID 9916793 DOI: 10.1038/5009 |
0.43 |
|
| 1998 |
Wu WS, Holmans P, Wavrant-DeVrièze F, Shears S, Kehoe P, Crook R, Booth J, Williams N, Pérez-Tur J, Roehl K, Fenton I, Chartier-Harlin MC, Lovestone S, Williams J, Hutton M, et al. Genetic studies on chromosome 12 in late-onset Alzheimer disease. Jama. 280: 619-22. PMID 9718053 DOI: 10.1001/Jama.280.7.619 |
0.389 |
|
| 1998 |
Lovestone S. Genetics consortiums can offer views facilitating best practice in Alzheimer's disease. Bmj (Clinical Research Ed.). 317: 471. PMID 9703537 DOI: 10.1136/Bmj.317.7156.471 |
0.407 |
|
| 1998 |
Holmes C, Arranz MJ, Powell JF, Collier DA, Lovestone S. 5-HT2A and 5-HT2C receptor polymorphisms and psychopathology in late onset Alzheimer's disease. Human Molecular Genetics. 7: 1507-9. PMID 9700207 DOI: 10.1093/Hmg/7.9.1507 |
0.408 |
|
| 1998 |
Gormley N, Rizwan MR, Lovestone S. Clinical predictors of aggressive behaviour in Alzheimer's disease. International Journal of Geriatric Psychiatry. 13: 109-15. PMID 9526180 DOI: 10.1002/(Sici)1099-1166(199802)13:2<109::Aid-Gps740>3.0.Co;2-F |
0.465 |
|
| 1998 |
Russ C, Powell J, Lovestone S, Holmes C. K variant of butyrycholinesterase and late-onset Alzheimer's disease. Lancet. 351: 881. PMID 9525372 DOI: 10.1016/S0140-6736(05)70292-0 |
0.402 |
|
| 1998 |
Holmes C, Russ C, Kirov G, Aitchison KJ, Powell JF, Collier DA, Lovestone S. Apolipoprotein E: depressive illness, depressive symptoms, and Alzheimer's disease. Biological Psychiatry. 43: 159-64. PMID 9494696 DOI: 10.1016/S0006-3223(97)00326-0 |
0.343 |
|
| 1997 |
Lovestone S. Muscarinic therapies in Alzheimer's disease; from palliative treatments to disease modification. International Journal of Psychiatry in Clinical Practice. 1: 15-20. PMID 24926977 DOI: 10.3109/13651509709069201 |
0.469 |
|
| 1997 |
Philpot M, Lewis K, Pereria ML, Ward C, Holmes C, Lovestone S, Fensom A, Seller M. Arylsulphatase A pseudodeficiency in vascular dementia and Alzheimer's disease. Neuroreport. 8: 2613-6. PMID 9261837 DOI: 10.1097/00001756-199707280-00038 |
0.393 |
|
| 1997 |
Lovestone S, Graham N, Howard R. Guidelines on drug treatments for Alzheimer's disease. Lancet. 350: 232-3. PMID 9242796 DOI: 10.1016/S0140-6736(05)62221-0 |
0.38 |
|
| 1997 |
Holmes C, Fortenza O, Powell J, Lovestone S. Do neuroleptic drugs hasten cognitive decline in dementia? Carriers of apolipoprotein E epsilon 4 allele seem particularly susceptible to their effects. Bmj (Clinical Research Ed.). 314: 1411; author reply 1. PMID 9161321 DOI: 10.1136/Bmj.314.7091.1411 |
0.318 |
|
| 1997 |
Li T, Holmes C, Sham PC, Vallada H, Birkett J, Kirov G, Lesch KP, Powell J, Lovestone S, Collier D. Allelic functional variation of serotonin transporter expression is a susceptibility factor for late onset Alzheimer's disease. Neuroreport. 8: 683-6. PMID 9106747 DOI: 10.1097/00001756-199702100-00021 |
0.411 |
|
| 1996 |
Holmes C, Levy R, McLoughlin DM, Powell JF, Lovestone S. Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 61: 580-3. PMID 8971103 DOI: 10.1136/Jnnp.61.6.580 |
0.413 |
|
| 1996 |
Kehoe P, Williams J, Holmans P, Liddell M, Lovestone S, Holmes C, Powell J, Neal J, Wilcock G, Owen MJ. Association between a PS-1 intronic polymorphism and late onset Alzheimer's disease. Neuroreport. 7: 2155-8. PMID 8930979 DOI: 10.1097/00001756-199609020-00019 |
0.421 |
|
| 1996 |
McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, Salmon DP, Lowe J, Mirra SS, Byrne EJ, Lennox G, Quinn NP, Edwardson JA, Ince PG, Bergeron C, ... ... Lovestone S, et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 47: 1113-24. PMID 8909416 DOI: 10.1212/Wnl.47.5.1113 |
0.434 |
|
| 1996 |
Lovestone S, Hartley CL, Pearce J, Anderton BH. Phosphorylation of tau by glycogen synthase kinase-3 beta in intact mammalian cells: the effects on the organization and stability of microtubules. Neuroscience. 73: 1145-57. PMID 8809831 DOI: 10.1016/0306-4522(96)00126-1 |
0.325 |
|
| 1996 |
Lovestone S, Anderton BH, Hartley C, Jensen TG, Jorgensen AL. The intracellular fate of apolipoprotein E is tau dependent and apoe allele-specific. Neuroreport. 7: 1005-8. PMID 8804040 DOI: 10.1097/00001756-199604100-00010 |
0.443 |
|
| 1996 |
Lovestone S, Wilcock G, Rossor M, Cayton H, Ragan I. Apolipoprotein E genotyping in Alzheimer's disease. The UK Alzheimer's Disease Genetic consortium. Lancet. 347: 1775-6. PMID 8656944 |
0.346 |
|
| 1996 |
Kehoe P, Williams J, Lovestone S, Wilcock G, Owen MJ. Presenilin-1 polymorphism and Alzheimer's disease. The UK Alzheimer's Disease Collaborative Group. Lancet. 347: 1185. PMID 8609781 |
0.35 |
|
| 1996 |
Jørgensen AL, Anderton BH, Hartley K, Jensen TG, Lovestone S. 753 The intracellular fate of apolipoprotein E is tau-dependent and APOE allele-specific Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80755-X |
0.328 |
|
| 1996 |
Hohnes C, Levy R, McLoughlin D, Powell J, Lovestone S. 385 Genetic and environmental risk factors : Association with non-cognitive symptoms and cognitive decline in late-onset Alzheimer's disease Neurobiology of Aging. 17: S96. DOI: 10.1016/S0197-4580(96)80387-3 |
0.371 |
|
| 1996 |
McKeith G, Morris C, Lovestone S, Wilcock G, Rossor M, Cayton H, Ragan I, Humphries S, Betteridge D, Durrington P, Galton D, Nicholls P. Apolipoprotein E genotyping in Alzheimer's disease The Lancet. 347: 1775-1776. DOI: 10.1016/S0140-6736(96)90857-0 |
0.429 |
|
| 1996 |
Kehoe P, Williams J, Lovestone S, Wilcock G, Owen M, Bouras C, Giannakopoulos P, Schioi J, Tezapsidis N, Robakis N, Higuchi S, Muramatsu T, Matsushita S, Arai H, Sasaki H, et al. Presenilin-1 polymorphism and Alzheimer's disease The Lancet. 347: 1185-1187. DOI: 10.1016/s0140-6736(96)90643-1 |
0.342 |
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