Khosrow Adeli - Publications

Affiliations: 
Biochemistry University of Toronto, Toronto, ON, Canada 
Area:
Physiology Biology, Biochemistry
Website:
http://biochemistry.utoronto.ca/person/khosrow-adeli/

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Higgins V, Adeli K. Postprandial dyslipidemia in insulin resistant states in adolescent populations. Journal of Biomedical Research. 34: 328-342. PMID 32934193 DOI: 10.7555/Jbr.34.20190094  0.371
2020 Farr S, Stankovic B, Hoffman S, Masoudpoor H, Baker C, Taher J, Dean A, Anakk S, Adeli K. Bile acid treatment and FXR agonism lower postprandial lipemia in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32003602 DOI: 10.1152/Ajpgi.00386.2018  0.327
2020 Alvares DCL, Hoffman SS, Adeli K. 580-P: Role of Bile Acids in Hepatic Lipid Metabolism: Characterization of the Fasting Lipid and Lipoprotein Profile of Tgr5-/- Hamsters Diabetes. 69. DOI: 10.2337/Db20-580-P  0.311
2019 Yu Y, Raka F, Adeli K. The Role of the Gut Microbiota in Lipid and Lipoprotein Metabolism. Journal of Clinical Medicine. 8. PMID 31861086 DOI: 10.3390/Jcm8122227  0.317
2019 Higgins V, Omidi A, Tahmasebi H, Asgari S, Gordanifar K, Nieuwesteeg M, Adeli K. Marked influence of adiposity on laboratory biomarkers in a healthy cohort of children and adolescents. The Journal of Clinical Endocrinology and Metabolism. PMID 31845996 DOI: 10.1210/Clinem/Dgz161  0.33
2019 Higgins V, Asgari S, Hamilton JK, Wolska A, Remaley AT, Hartmann B, Holst JJ, Adeli K. Postprandial dyslipidemia, hyperinsulinemia, and impaired gut peptides/bile acids in adolescents with obesity. The Journal of Clinical Endocrinology and Metabolism. PMID 31825485 DOI: 10.1210/Clinem/Dgz261  0.335
2019 Hoffman S, Alvares D, Adeli K. Intestinal lipogenesis: how carbs turn on triglyceride production in the gut. Current Opinion in Clinical Nutrition and Metabolic Care. PMID 31107259 DOI: 10.1097/Mco.0000000000000569  0.301
2019 Alvares D, Hoffman S, Stankovic B, Adeli K. Gut peptide and neuroendocrine regulation of hepatic lipid and lipoprotein metabolism in health and disease. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 1864: 326-334. PMID 30578967 DOI: 10.1016/J.Bbalip.2018.12.010  0.331
2019 Higgins V, Asgari S, Adeli K. Postprandial dyslipidemia in obese and insulin resistant adolescents: Evidence for impaired response of intestinal glucagon-like peptides and abnormal bile acid profile Clinica Chimica Acta. 493: S308. DOI: 10.1016/J.Cca.2019.03.634  0.32
2018 Taher J, Baker C, Alvares D, Ijaz L, Hussain M, Adeli K. GLP-2 Dysregulates Hepatic Lipoprotein Metabolism Inducing Fatty Liver and VLDL Overproduction In Male Hamsters and Mice. Endocrinology. PMID 30052880 DOI: 10.1210/En.2018-00416  0.349
2018 Higgins V, Asgari S, Chan MK, Adeli K. Pediatric reference intervals for calculated LDL cholesterol, non-HDL cholesterol, and remnant cholesterol in the healthy CALIPER cohort. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 30025755 DOI: 10.1016/J.Cca.2018.07.028  0.326
2018 Hoffman S, Adeli K. Portal Vein GLP-1 Receptor Activation Modulates Dietary Fat Absorption and Intestinal Lipoprotein Metabolism Atherosclerosis Supplements. 32: 58-59. DOI: 10.1016/J.Atherosclerosissup.2018.04.176  0.302
2018 Alvares DC, Baker C, Adeli K. Neuregulin 4 (Nrg4) Regulation of Hepatic Lipid and Lipoprotein Metabolism in the Hamster Model Atherosclerosis Supplements. 32: 56. DOI: 10.1016/J.Atherosclerosissup.2018.04.168  0.312
2018 Higgins V, Asgari S, Chan MK, Adeli K. Postprandial GLP-1 Response to a High-fat Meal is Blunted in Obese Adolescents with Insulin Resistance and Metabolic Dyslipidemia Atherosclerosis Supplements. 32: 20-21. DOI: 10.1016/J.Atherosclerosissup.2018.04.061  0.314
2017 Khound R, Taher J, Baker C, Adeli K, Su Q. GLP-1 Elicits an Intrinsic Gut-Liver Metabolic Signal to Ameliorate Diet-Induced VLDL Overproduction and Insulin Resistance. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29074588 DOI: 10.1161/Atvbaha.117.310251  0.352
2017 Adeli K, Higgins V, Trajcevski K, White-Al Habeeb N. The Canadian laboratory initiative on pediatric reference intervals: A CALIPER white paper. Critical Reviews in Clinical Laboratory Sciences. 1-56. PMID 29017389 DOI: 10.1080/10408363.2017.1379945  0.302
2017 Abbasi Oshaghi E, Goodarzi MT, Higgins V, Adeli K. Role of resveratrol in the management of insulin resistance and related conditions: Mechanism of action. Critical Reviews in Clinical Laboratory Sciences. 1-27. PMID 28704113 DOI: 10.1080/10408363.2017.1343274  0.324
2017 Zhang J, Zamani M, Thiele C, Taher J, Amir Alipour M, Yao Z, Adeli K. AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28183703 DOI: 10.1161/Atvbaha.117.309000  0.341
2016 Taher J, Farr S, Adeli K. Central nervous system regulation of hepatic lipid and lipoprotein metabolism. Current Opinion in Lipidology. PMID 27906714 DOI: 10.1097/Mol.0000000000000373  0.357
2016 Anderson LN, Maguire JL, Lebovic G, Hanley AJ, Hamilton J, Adeli K, McCrindle BW, Borkhoff CM, Parkin PC, Birken CS. Duration of Fasting, Serum Lipids, and Metabolic Profile in Early Childhood. The Journal of Pediatrics. PMID 27742126 DOI: 10.1016/J.Jpeds.2016.09.005  0.309
2016 Zamani M, Taher J, Adeli K. Complex role of autophagy in regulation of hepatic lipid and lipoprotein metabolism. Journal of Biomedical Research. 30. PMID 27346467 DOI: 10.7555/Jbr.30.20150137  0.34
2016 Bashiri A, Nesan D, Tavallaee G, Sue-Chue-Lam I, Chien K, Maguire GF, Naples M, Zhang J, Magomedova L, Adeli K, Cummins CL, Ng DS. Cellular cholesterol accumulation modulates high fat high sucrose (HFHS) diet-induced ER stress and hepatic inflammasome activation in the development of non-alcoholic steatohepatitis. Biochimica Et Biophysica Acta. PMID 27090939 DOI: 10.1016/J.Bbalip.2016.04.005  0.309
2016 Farr S, Taher J, Adeli K. Central nervous system regulation of intestinal lipid and lipoprotein metabolism. Current Opinion in Lipidology. 27: 1-7. PMID 26628437 DOI: 10.1097/Mol.0000000000000254  0.322
2015 Karbasy K, Ariadne P, Gaglione S, Nieuwesteeg M, Adeli K. Advances in Pediatric Reference Intervals for Biochemical Markers: Establishment of the Caliper Database in Healthy Children and Adolescents. Journal of Medical Biochemistry. 34: 23-30. PMID 28356820 DOI: 10.2478/Jomb-2014-0063  0.302
2015 Gorgani-Firuzjaee S, Khatami S, Adeli K, Meshkani R. SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells. Biochemical and Biophysical Research Communications. 464: 1028-33. PMID 26188518 DOI: 10.1016/J.Bbrc.2015.07.059  0.32
2015 Lino M, Farr S, Baker C, Fuller M, Trigatti B, Adeli K. Intestinal scavenger receptor class B type I (SR-BI) as a novel regulator of chylomicron production in healthy and diet-induced obese states. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00086.2015. PMID 26138463 DOI: 10.1152/Ajpgi.00086.2015  0.346
2015 Hsieh J, Trajcevski KE, Farr SL, Baker CL, Lake EJ, Taher J, Iqbal J, Hussain MM, Adeli K. Glucagon-like peptide 2 (GLP-2) stimulates postprandial chylomicron production and post-absorptive release of intestinal triglyceride storage pools via induction of nitric oxide signalling in male hamsters and mice. Endocrinology. EN20151110. PMID 26132919 DOI: 10.1210/En.2015-1110  0.618
2015 Xiao C, Dash S, Morgantini C, Adeli K, Lewis GF. Gut Peptides Are Novel Regulators of Intestinal Lipoprotein Secretion: Experimental and Pharmacological Manipulation of Lipoprotein Metabolism. Diabetes. 64: 2310-8. PMID 26106188 DOI: 10.2337/Db14-1706  0.355
2015 Farr S, Baker C, Naples M, Taher J, Iqbal J, Hussain M, Adeli K. Central Nervous System Regulation of Intestinal Lipoprotein Metabolism by Glucagon-Like Peptide-1 via a Brain-Gut Axis. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 1092-100. PMID 25675997 DOI: 10.1161/Atvbaha.114.304873  0.324
2014 Taher J, Baker CL, Cuizon C, Masoudpour H, Zhang R, Farr S, Naples M, Bourdon C, Pausova Z, Adeli K. GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance. Molecular Metabolism. 3: 823-33. PMID 25506548 DOI: 10.1016/J.Molmet.2014.09.005  0.361
2014 Farr S, Taher J, Adeli K. Glucagon-like peptide-1 as a key regulator of lipid and lipoprotein metabolism in fasting and postprandial states. Cardiovascular & Hematological Disorders Drug Targets. 14: 126-36. PMID 24801723 DOI: 10.2174/1871529X14666140505125300  0.391
2013 Lu J, Ji J, Meng H, Wang D, Jiang B, Liu L, Randell E, Adeli K, Meng QH. The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovascular Diabetology. 12: 58. PMID 23561047 DOI: 10.1186/1475-2840-12-58  0.313
2013 Dekker MJ, Baker C, Naples M, Samsoondar J, Zhang R, Qiu W, Sacco J, Adeli K. Inhibition of sphingolipid synthesis improves dyslipidemia in the diet-induced hamster model of insulin resistance: evidence for the role of sphingosine and sphinganine in hepatic VLDL-apoB100 overproduction. Atherosclerosis. 228: 98-109. PMID 23466071 DOI: 10.1016/J.Atherosclerosis.2013.01.041  0.376
2013 Christian P, Sacco J, Adeli K. Autophagy: Emerging roles in lipid homeostasis and metabolic control. Biochimica Et Biophysica Acta. 1831: 819-24. PMID 23274236 DOI: 10.1016/J.Bbalip.2012.12.009  0.347
2013 Pinkosky SL, Filippov S, Srivastava RA, Hanselman JC, Bradshaw CD, Hurley TR, Cramer CT, Spahr MA, Brant AF, Houghton JL, Baker C, Naples M, Adeli K, Newton RS. AMP-activated protein kinase and ATP-citrate lyase are two distinct molecular targets for ETC-1002, a novel small molecule regulator of lipid and carbohydrate metabolism. Journal of Lipid Research. 54: 134-51. PMID 23118444 DOI: 10.1194/Jlr.M030528  0.324
2013 Hein GJ, Baker C, Hsieh J, Farr S, Adeli K. GLP-1 and GLP-2 as yin and yang of intestinal lipoprotein production: evidence for predominance of GLP-2-stimulated postprandial lipemia in normal and insulin-resistant states. Diabetes. 62: 373-81. PMID 23028139 DOI: 10.2337/Db12-0202  0.646
2012 Hsieh J, Adeli K. Regulation of intestinal chylomicron production by glucagon-like peptides. Cardiovascular & Hematological Disorders Drug Targets. 12: 92-7. PMID 23030446 DOI: 10.2174/1871529X11202020092  0.647
2012 Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2104-12. PMID 22796579 DOI: 10.1161/Atvbaha.111.241463  0.37
2012 Hager L, Li L, Pun H, Liu L, Hossain MA, Maguire GF, Naples M, Baker C, Magomedova L, Tam J, Adeli K, Cummins CL, Connelly PW, Ng DS. Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice. The Journal of Biological Chemistry. 287: 20755-68. PMID 22500017 DOI: 10.1074/Jbc.M112.340919  0.334
2012 Yue JT, Mighiu PI, Naples M, Adeli K, Lam TK. Glycine normalizes hepatic triglyceride-rich VLDL secretion by triggering the CNS in high-fat fed rats. Circulation Research. 110: 1345-54. PMID 22474253 DOI: 10.1161/Circresaha.112.268276  0.313
2012 Colantonio DA, Kyriakopoulou L, Chan MK, Daly CH, Brinc D, Venner AA, Pasic MD, Armbruster D, Adeli K. Closing the gaps in pediatric laboratory reference intervals: a CALIPER database of 40 biochemical markers in a healthy and multiethnic population of children. Clinical Chemistry. 58: 854-68. PMID 22371482 DOI: 10.1373/Clinchem.2011.177741  0.3
2012 Naples M, Baker C, Lino M, Iqbal J, Hussain MM, Adeli K. Ezetimibe ameliorates intestinal chylomicron overproduction and improves glucose tolerance in a diet-induced hamster model of insulin resistance. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G1043-52. PMID 22345552 DOI: 10.1152/Ajpgi.00250.2011  0.371
2012 Shi SY, Martin RG, Duncan RE, Choi D, Lu SY, Schroer SA, Cai EP, Luk CT, Hopperton KE, Domenichiello AF, Tang C, Naples M, Dekker MJ, Giacca A, Adeli K, et al. Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. The Journal of Biological Chemistry. 287: 10277-88. PMID 22275361 DOI: 10.1074/Jbc.M111.317453  0.347
2012 Farr S, Adeli K. Incretin-based therapies for treatment of postprandial dyslipidemia in insulin-resistant states. Current Opinion in Lipidology. 23: 56-61. PMID 22123671 DOI: 10.1097/Mol.0B013E32834D68F0  0.321
2011 Adeli K. Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules. American Journal of Physiology. Endocrinology and Metabolism. 301: E1051-64. PMID 21971522 DOI: 10.1152/Ajpendo.00399.2011  0.313
2011 Xiao C, Hsieh J, Adeli K, Lewis GF. Gut-liver interaction in triglyceride-rich lipoprotein metabolism. American Journal of Physiology. Endocrinology and Metabolism. 301: E429-46. PMID 21693689 DOI: 10.1152/Ajpendo.00178.2011  0.623
2011 Hayashi AA, Webb J, Choi J, Baker C, Lino M, Trigatti B, Trajcevski KE, Hawke TJ, Adeli K. Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G326-37. PMID 21546579 DOI: 10.1152/Ajpgi.00425.2010  0.379
2011 Warnakula S, Hsieh J, Adeli K, Hussain MM, Tso P, Proctor SD. New insights into how the intestine can regulate lipid homeostasis and impact vascular disease: frontiers for new pharmaceutical therapies to lower cardiovascular disease risk. The Canadian Journal of Cardiology. 27: 183-91. PMID 21459267 DOI: 10.1016/J.Cjca.2010.12.020  0.629
2011 Xi L, Xiao C, Bandsma RH, Naples M, Adeli K, Lewis GF. C-reactive protein impairs hepatic insulin sensitivity and insulin signaling in rats: role of mitogen-activated protein kinases. Hepatology (Baltimore, Md.). 53: 127-35. PMID 20967757 DOI: 10.1002/Hep.24011  0.329
2011 Diamandis Pasic M, Colantonio D, Kyriakopoulou L, Chan M, Venner A, Brinc D, Fu L, Yip P, Armbruster D, Adeli K. Pediatric reference intervals for serum lipids and lipoproteins on the Abbott ARCHITECT c8000: A CALIPER study of healthy community children Clinical Biochemistry. 44: 528. DOI: 10.1016/J.Clinbiochem.2011.03.060  0.303
2010 Kelishadi R, Hashemipour M, Adeli K, Tavakoli N, Movahedian-Attar A, Shapouri J, Poursafa P, Rouzbahani A. Effect of zinc supplementation on markers of insulin resistance, oxidative stress, and inflammation among prepubescent children with metabolic syndrome. Metabolic Syndrome and Related Disorders. 8: 505-10. PMID 21028969 DOI: 10.1089/Met.2010.0020  0.316
2010 Dekker MJ, Su Q, Baker C, Rutledge AC, Adeli K. Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome. American Journal of Physiology. Endocrinology and Metabolism. 299: E685-94. PMID 20823452 DOI: 10.1152/Ajpendo.00283.2010  0.343
2010 Bakhtiyari S, Meshkani R, Taghikhani M, Larijani B, Adeli K. Protein tyrosine phosphatase-1B (PTP-1B) knockdown improves palmitate-induced insulin resistance in C2C12 skeletal muscle cells. Lipids. 45: 237-44. PMID 20177806 DOI: 10.1007/S11745-010-3394-3  0.329
2010 Wong DM, Webb JP, Malinowski PM, Xu E, Macri J, Adeli K. Proteomic profiling of intestinal prechylomicron transport vesicle (PCTV)-associated proteins in an animal model of insulin resistance (94 char). Journal of Proteomics. 73: 1291-305. PMID 20117256 DOI: 10.1016/J.Jprot.2010.01.010  0.365
2010 Dong B, Wu M, Li H, Kraemer FB, Adeli K, Seidah NG, Park SW, Liu J. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters. Journal of Lipid Research. 51: 1486-95. PMID 20048381 DOI: 10.1194/Jlr.M003566  0.325
2010 Hsieh J, Longuet C, Baker CL, Qin B, Federico LM, Drucker DJ, Adeli K. The glucagon-like peptide 1 receptor is essential for postprandial lipoprotein synthesis and secretion in hamsters and mice. Diabetologia. 53: 552-61. PMID 19957161 DOI: 10.1007/S00125-009-1611-5  0.605
2010 Simoneau-Roy J, O'Gorman C, Pencharz P, Adeli K, Daneman D, Hamilton J. Insulin sensitivity and secretion in children and adolescents with hypothalamic obesity following treatment for craniopharyngioma. Clinical Endocrinology. 72: 364-70. PMID 19486023 DOI: 10.1111/J.1365-2265.2009.03639.X  0.322
2010 Su Q, Rutledge AC, Dekker M, Adeli K. Apolipoprotein B: Not just a biomarker but a causal factor in hepatic endoplasmic reticulum stress and insulin resistance Clinical Lipidology. 5: 267-276. DOI: 10.2217/Clp.10.15  0.335
2010 Hsieh J, Baker CL, Adeli K. Glucagon-Like Peptide-2-Stimulated Intestinal Fat Absorption is Dependent on Nitric Oxide Synthase Atherosclerosis Supplements. 11: 76. DOI: 10.1016/J.Atherosclerosissup.2010.04.028  0.574
2010 Hsieh J, Adeli K. Glucagon-like Peptides (GLP-1 and GLP-2) as Ying and Yang of Intestinal Lipid Absorption and Chylomicron Production Atherosclerosis Supplements. 11: 67. DOI: 10.1016/J.Atherosclerosissup.2010.04.012  0.591
2009 Basciano H, Miller AE, Naples M, Baker C, Kohen R, Xu E, Su Q, Allister EM, Wheeler MB, Adeli K. Metabolic effects of dietary cholesterol in an animal model of insulin resistance and hepatic steatosis. American Journal of Physiology. Endocrinology and Metabolism. 297: E462-73. PMID 19509184 DOI: 10.1152/Ajpendo.90764.2008  0.374
2009 Meshkani R, Adeli K. Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. Clinical Biochemistry. 42: 1331-46. PMID 19501581 DOI: 10.1016/J.Clinbiochem.2009.05.018  0.307
2009 Basciano H, Miller A, Baker C, Naples M, Adeli K. LXRalpha activation perturbs hepatic insulin signaling and stimulates production of apolipoprotein B-containing lipoproteins. American Journal of Physiology. Gastrointestinal and Liver Physiology. 297: G323-32. PMID 19497957 DOI: 10.1152/Ajpgi.90546.2008  0.36
2009 Hsieh J, Longuet C, Maida A, Bahrami J, Xu E, Baker CL, Brubaker PL, Drucker DJ, Adeli K. Glucagon-like peptide-2 increases intestinal lipid absorption and chylomicron production via CD36. Gastroenterology. 137: 997-1005, 1005.e1-4. PMID 19482026 DOI: 10.1053/J.Gastro.2009.05.051  0.605
2009 Su Q, Tsai J, Xu E, Qiu W, Bereczki E, Santha M, Adeli K. Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance. Hepatology (Baltimore, Md.). 50: 77-84. PMID 19434737 DOI: 10.1002/Hep.22960  0.331
2009 Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K. Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G1287-98. PMID 19342510 DOI: 10.1152/Ajpgi.90540.2008  0.333
2009 Qin B, Polansky MM, Sato Y, Adeli K, Anderson RA. Cinnamon extract inhibits the postprandial overproduction of apolipoprotein B48-containing lipoproteins in fructose-fed animals Journal of Nutritional Biochemistry. 20: 901-908. PMID 18993048 DOI: 10.1016/J.Jnutbio.2008.08.005  0.385
2008 Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K. Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins. Hepatology (Baltimore, Md.). 48: 1799-809. PMID 19026012 DOI: 10.1002/Hep.22565  0.334
2008 Hsieh J, Hayashi AA, Webb J, Adeli K. Postprandial dyslipidemia in insulin resistance: mechanisms and role of intestinal insulin sensitivity. Atherosclerosis. Supplements. 9: 7-13. PMID 18653387 DOI: 10.1016/J.Atherosclerosissup.2008.05.011  0.646
2008 Adeli K, Lewis GF. Intestinal lipoprotein overproduction in insulin-resistant states. Current Opinion in Lipidology. 19: 221-8. PMID 18460911 DOI: 10.1097/Mol.0B013E3282Ffaf82  0.344
2008 Qin B, Anderson RA, Adeli K. Tumor necrosis factor-α directly stimulates the overproduction of hepatic apolipoprotein B100-containing VLDL via impairment of hepatic insulin signaling American Journal of Physiology - Gastrointestinal and Liver Physiology. 294. PMID 18372392 DOI: 10.1152/Ajpgi.00407.2007  0.325
2008 Nerurkar PV, Lee YK, Motosue M, Adeli K, Nerurkar VR. Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions. The British Journal of Nutrition. 100: 751-9. PMID 18321395 DOI: 10.1017/S0007114508937430  0.35
2008 Miller A, Adeli K. Dietary fructose and the metabolic syndrome Current Opinion in Gastroenterology. 24: 204-209. PMID 18301272 DOI: 10.1097/Mog.0B013E3282F3F4C4  0.311
2008 Naples M, Federico LM, Xu E, Nelken J, Adeli K. Effect of rosuvastatin on insulin sensitivity in an animal model of insulin resistance: Evidence for statin-induced hepatic insulin sensitization Atherosclerosis. 198: 94-103. PMID 18093597 DOI: 10.1016/J.Atherosclerosis.2007.11.003  0.335
2008 Hayashi A, Webb J, Baker C, Adeli K. Expression levels of intestinal lipid transporters in the fructose fed hamster model of insulin resistance Atherosclerosis Supplements. 9: 96. DOI: 10.1016/J.Atherosclerosissup.2008.09.421  0.336
2008 Baker C, Naples M, Hsieh J, Adeli K. Sitaglipin treatment attenuates triglyceride rich lipoprotein accumulation in fructose fed syrian gold hamsters Atherosclerosis Supplements. 9: 89. DOI: 10.1016/J.Atherosclerosissup.2008.09.409  0.584
2008 Hsieh J, Longuet C, Xu E, Baker C, Brubaker P, Drucker D, Adeli K. Glucagon-like peptide-2 (GLP-2) is a potent mediator of intestinal ApoB48-containing lipoprotein overproduction Atherosclerosis Supplements. 9: 84-85. DOI: 10.1016/J.Atherosclerosissup.2008.09.400  0.589
2007 Sidiropoulos KG, Meshkani R, Avramoglu-Kohen R, Adeli K. Insulin inhibition of apolipoprotein B mRNA translation is mediated via the PI-3 kinase/mTOR signaling cascade but does not involve internal ribosomal entry site (IRES) initiation Archives of Biochemistry and Biophysics. 465: 380-388. PMID 17698027 DOI: 10.1016/J.Abb.2007.06.029  0.311
2007 Rutledge AC, Adeli K. Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms. Nutrition Reviews. 65: S13-23. PMID 17605309 DOI: 10.1111/J.1753-4887.2007.Tb00322.X  0.307
2007 Meshkani R, Taghikhani M, Mosapour A, Larijani B, Khatami S, Khoshbin E, Ahmadvand D, Saeidi P, Maleki A, Yavari K, Nasoohi N, Adeli K. 1484insG Polymorphism of the PTPN1 Gene Is Associated with Insulin Resistance in an Iranian Population Archives of Medical Research. 38: 556-562. PMID 17560463 DOI: 10.1016/J.Arcmed.2007.01.010  0.304
2007 Li L, Naples M, Song H, Yuan R, Ye F, Shafi S, Adeli K, Ng DS. LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling. American Journal of Physiology. Endocrinology and Metabolism. 293: E587-94. PMID 17551001 DOI: 10.1152/Ajpendo.00278.2007  0.325
2007 Sidiropoulos KG, Zastepa A, Adeli K. Translational control of apolipoprotein B mRNA via insulin and the protein kinase C signaling cascades: Evidence for modulation of RNA-protein interactions at the 5′UTR Archives of Biochemistry and Biophysics. 459: 10-19. PMID 17288985 DOI: 10.1016/J.Abb.2006.11.003  0.348
2007 Qin B, Qiu W, Avramoglu RK, Adeli K. Tumor necrosis factor-alpha induces intestinal insulin resistance and stimulates the overproduction of intestinal apolipoprotein B48-containing lipoproteins. Diabetes. 56: 450-61. PMID 17259391 DOI: 10.2337/Db06-0518  0.303
2007 Kelishadi R, Sharifi M, Khosravi A, Adeli K. Relationship between C-reactive protein and atherosclerotic risk factors and oxidative stress markers among young persons 10-18 years old Clinical Chemistry. 53: 456-464. PMID 17259238 DOI: 10.1373/Clinchem.2006.073668  0.313
2007 Su Q, Tsai J, Adeli K. 147 Co-translational Misfolding and Endoplasmic Reticulum Accumulation of Apolipoprotein B Induces Hepatic Insulin Resistance Cytokine. 39: 41. DOI: 10.1016/J.Cyto.2007.07.152  0.321
2006 Kelishadi R, Ardalan G, Gheiratmand R, Adeli K, Delavari A, Majdzadeh R. Paediatric metabolic syndrome and associated anthropometric indices: The CASPIAN study Acta Paediatrica, International Journal of Paediatrics. 95: 1625-1634. PMID 17129973 DOI: 10.1080/08035250600750072  0.307
2006 Yip PM, Chan MK, Nelken J, Lepage N, Brotea G, Adeli K. Pediatric reference intervals for lipids and apolipoproteins on the VITROS 5,1 FS Chemistry System. Clinical Biochemistry. 39: 978-83. PMID 16962571 DOI: 10.1016/J.Clinbiochem.2006.06.012  0.314
2006 Meshkani R, Taghikhani M, Larijani B, Khatami S, Khoshbin E, Adeli K. The relationship between homeostasis model assessment and cardiovascular risk factors in Iranian subjects with normal fasting glucose and normal glucose tolerance Clinica Chimica Acta. 371: 169-175. PMID 16714005 DOI: 10.1016/J.Cca.2006.03.018  0.323
2006 Qiu W, Avramoglu RK, Rutledge AC, Tsai J, Adeli K. Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteins. Journal of Lipid Research. 47: 1749-61. PMID 16672736 DOI: 10.1194/Jlr.M500363-Jlr200  0.309
2006 Federico LM, Naples M, Taylor D, Adeli K. Intestinal insulin resistance and aberrant production of apolipoprotein B48 lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia: Evidence for activation of protein tyrosine phosphatase-1B, extracellular signal-related kinase, and sterol regulatory element-binding protein-1c in the fructose-fed hamster intestine Diabetes. 55: 1316-1326. PMID 16644688 DOI: 10.2337/Db04-1084  0.372
2006 Mansoub S, Chan MK, Adeli K. Gap analysis of pediatric reference intervals for risk biomarkers of cardiovascular disease and the metabolic syndrome Clinical Biochemistry. 39: 569-587. PMID 16624272 DOI: 10.1016/J.Clinbiochem.2006.02.013  0.334
2006 Sarkissian T, Beyenne J, Feldman B, Adeli K, Silverman E. The complex nature of the interaction between disease activity and therapy on the lipid profile in patients with pediatric systemic lupus erythematosus Arthritis and Rheumatism. 54: 1283-1290. PMID 16575849 DOI: 10.1002/Art.21748  0.312
2006 Avramoglu RK, Basciano H, Adeli K. Lipid and lipoprotein dysregulation in insulin resistant states. Clinica Chimica Acta; International Journal of Clinical Chemistry. 368: 1-19. PMID 16480697 DOI: 10.1016/J.Cca.2005.12.026  0.387
2006 Li RW, Douglas TD, Maiyoh GK, Adeli K, Theriault AG. Green tea leaf extract improves lipid and glucose homeostasis in a fructose-fed insulin-resistant hamster model. Journal of Ethnopharmacology. 104: 24-31. PMID 16202550 DOI: 10.1016/J.Jep.2005.08.045  0.337
2006 Chong T, Naples M, Federico L, Taylor D, Smith GJ, Cheung RC, Adeli K. Effect of rosuvastatin on hepatic production of apolipoprotein B-containing lipoproteins in an animal model of insulin resistance and metabolic dyslipidemia Atherosclerosis. 185: 21-31. PMID 16002078 DOI: 10.1016/J.Atherosclerosis.2005.05.010  0.37
2006 Federico L, Naples M, Taylor D, Adeli K. Mo-W8:6 Effect of rosuvastatin on hepatic and whole body insulin sensitivity in an animal model of insulin resistance and metabolic syndrome Atherosclerosis Supplements. 7: 25-26. DOI: 10.1016/S1567-5688(06)80074-7  0.329
2005 Sidiropoulos KG, Pontrelli L, Adeli K. Insulin-mediated suppression of apolipoprotein B mRNA translation requires the 5′ UTR and is characterized by decreased binding of an insulin-sensitive 110-kDa 5′ UTR RNA-binding protein Biochemistry. 44: 12572-12581. PMID 16156669 DOI: 10.1021/Bi050368E  0.326
2005 Mielke JG, Taghibiglou C, Liu L, Zhang Y, Jia Z, Adeli K, Wang YT. A biochemical and functional characterization of diet-induced brain insulin resistance. Journal of Neurochemistry. 93: 1568-78. PMID 15935073 DOI: 10.1111/J.1471-4159.2005.03155.X  0.327
2005 Guo Q, Avramoglu RK, Adeli K. Intestinal assembly and secretion of highly dense/lipid-poor apolipoprotein B48-containing lipoprotein particles in the fasting state: evidence for induction by insulin resistance and exogenous fatty acids. Metabolism: Clinical and Experimental. 54: 689-97. PMID 15877301 DOI: 10.1016/J.Metabol.2004.12.014  0.336
2005 Nerurkar PV, Pearson L, Efird JT, Adeli K, Theriault AG, Nerurkar VR. Microsomal triglyceride transfer protein gene expression and ApoB secretion are inhibited by bitter melon in HepG2 cells. The Journal of Nutrition. 135: 702-6. PMID 15795421 DOI: 10.1093/Jn/135.4.702  0.363
2005 Morand JPF, Macri J, Adeli K. Proteomic profiling of hepatic endoplasmic reticulum-associated proteins in an animal model of insulin resistance and metabolic dyslipidemia Journal of Biological Chemistry. 280: 17626-17633. PMID 15760893 DOI: 10.1074/Jbc.M413343200  0.35
2005 Casaschi A, Maiyoh GK, Adeli K, Theriault AG. Increased diacylglycerol acyltransferase activity is associated with triglyceride accumulation in tissues of diet-induced insulin-resistant hyperlipidemic hamsters. Metabolism: Clinical and Experimental. 54: 403-9. PMID 15736121 DOI: 10.1016/J.Metabol.2004.09.016  0.328
2005 Basciano H, Federico L, Adeli K. Fructose, insulin resistance, and metabolic dyslipidemia. Nutrition & Metabolism. 2: 5. PMID 15723702 DOI: 10.1186/1743-7075-2-5  0.356
2005 Qiu W, Taghibiglou C, Avramoglu RK, Van Iderstine SC, Naples M, Ashrafpour H, Mhapsekar S, Sato R, Adeli K. Oleate-mediated stimulation of microsomal triglyceride transfer protein (MTP) gene promoter: implications for hepatic MTP overexpression in insulin resistance. Biochemistry. 44: 3041-9. PMID 15723548 DOI: 10.1021/Bi047803+  0.353
2005 Lewis GF, Uffelman K, Naples M, Szeto L, Haidari M, Adeli K. Intestinal lipoprotein overproduction, a newly recognized component of insulin resistance, is ameliorated by the insulin sensitizer rosiglitazone: studies in the fructose-fed Syrian golden hamster. Endocrinology. 146: 247-55. PMID 15486228 DOI: 10.1210/En.2004-1143  0.379
2005 Adeli K, Federico L, Naples M, Taylor D. W09-O-001 Rosuvastatin inhibits intestinal production of atherogenic lipoproteins in a hamster model of insulin resistance and metabolic dyslipidemia Atherosclerosis Supplements. 6: 39. DOI: 10.1016/S1567-5688(05)80154-0  0.332
2004 Qiu W, Avramoglu RK, Dubé N, Chong TM, Naples M, Au C, Sidiropoulos KG, Lewis GF, Cohn JS, Tremblay ML, Adeli K. Hepatic PTP-1B expression regulates the assembly and secretion of apolipoprotein B-containing lipoproteins: evidence from protein tyrosine phosphatase-1B overexpression, knockout, and RNAi studies. Diabetes. 53: 3057-66. PMID 15561934 DOI: 10.2337/Diabetes.53.12.3057  0.332
2004 Lewis GF, Murdoch S, Uffelman K, Naples M, Szeto L, Albers A, Adeli K, Brunzell JD. Hepatic lipase mRNA, protein, and plasma enzyme activity is increased in the insulin-resistant, fructose-fed Syrian golden hamster and is partially normalized by the insulin sensitizer rosiglitazone. Diabetes. 53: 2893-900. PMID 15504970 DOI: 10.2337/Diabetes.53.11.2893  0.355
2004 Lewis GF, Naples M, Uffelman K, Leung N, Szeto L, Adeli K. Intestinal lipoprotein production is stimulated by an acute elevation of plasma free fatty acids in the fasting state: studies in insulin-resistant and insulin-sensitized Syrian golden hamsters. Endocrinology. 145: 5006-12. PMID 15271878 DOI: 10.1210/En.2003-1559  0.356
2004 Casaschi A, Maiyoh GK, Rubio BK, Li RW, Adeli K, Theriault AG. The chalcone xanthohumol inhibits triglyceride and apolipoprotein B secretion in HepG2 cells. The Journal of Nutrition. 134: 1340-6. PMID 15173394 DOI: 10.1093/Jn/134.6.1340  0.326
2004 Leung N, Naples M, Uffelman K, Szeto L, Adeli K, Lewis GF. Rosiglitazone improves intestinal lipoprotein overproduction in the fat-fed Syrian Golden hamster, an animal model of nutritionally-induced insulin resistance. Atherosclerosis. 174: 235-41. PMID 15136053 DOI: 10.1016/J.Atherosclerosis.2004.02.005  0.353
2004 Au CS, Wagner A, Chong T, Qiu W, Sparks JD, Adeli K. Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism: Clinical and Experimental. 53: 228-35. PMID 14767876 DOI: 10.1016/J.Metabol.2003.09.011  0.334
2004 Chong T, Naples N, Federico L, Taylor D, Cheung R, Adeli K. W09.212 Effect of rosuvastatin on hepatic production of atherogenic lipoproteins in an animal model of insulin resistance and diabetic dyslipidemia Atherosclerosis Supplements. 5: 49. DOI: 10.1016/S1567-5688(04)90211-0  0.319
2004 Ragheb R, Adeli K, Fantus G. TISSUE-SPECIFIC EFFECT OF FATTY ACIDS ON INSULIN SENSITIVITY: EVIDENCE THAT FATTY ACIDS, OLEATE AND PALMITATE, INDUCE MUSCLE INSULIN RESISTANCE BUT HAVE NO EFFECT ON HEPATIC INSULIN SENSITIVITY Cardiovascular Pathology. 13: 88-89. DOI: 10.1016/J.Carpath.2004.03.262  0.308
2003 Kohen-Avramoglu R, Theriault A, Adeli K. Emergence of the metabolic syndrome in childhood: an epidemiological overview and mechanistic link to dyslipidemia. Clinical Biochemistry. 36: 413-20. PMID 12951167 DOI: 10.1016/S0009-9120(03)00038-9  0.364
2003 Avramoglu RK, Qiu W, Adeli K. Mechanisms of metabolic dyslipidemia in insulin resistant states: deregulation of hepatic and intestinal lipoprotein secretion. Frontiers in Bioscience : a Journal and Virtual Library. 8: d464-76. PMID 12456312 DOI: 10.2741/1022  0.383
2002 Haidari M, Leung N, Mahbub F, Uffelman KD, Kohen-Avramoglu R, Lewis GF, Adeli K. Fasting and postprandial overproduction of intestinally derived lipoproteins in an animal model of insulin resistance. Evidence that chronic fructose feeding in the hamster is accompanied by enhanced intestinal de novo lipogenesis and ApoB48-containing lipoprotein overproduction. The Journal of Biological Chemistry. 277: 31646-55. PMID 12070142 DOI: 10.1074/Jbc.M200544200  0.381
2002 Bonn V, Cheung RC, Chen B, Taghibiglou C, Van Iderstine SC, Adeli K. Simvastatin, an HMG-CoA reductase inhibitor, induces the synthesis and secretion of apolipoprotein AI in HepG2 cells and primary hamster hepatocytes. Atherosclerosis. 163: 59-68. PMID 12048122 DOI: 10.1016/S0021-9150(01)00754-7  0.3
2002 Lewis GF, Carpentier A, Adeli K, Giacca A. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocrine Reviews. 23: 201-29. PMID 11943743 DOI: 10.1210/Edrv.23.2.0461  0.351
2002 Mangaloglu L, Cheung RC, Van Iderstine SC, Taghibiglou C, Pontrelli L, Adeli K. Treatment with atorvastatin ameliorates hepatic very-low-density lipoprotein overproduction in an animal model of insulin resistance, the fructose-fed Syrian golden hamster: evidence that reduced hypertriglyceridemia is accompanied by improved hepatic insulin sensitivity. Metabolism: Clinical and Experimental. 51: 409-18. PMID 11912545 DOI: 10.1053/Meta.2002.30954  0.365
2002 Pontrelli L, Parris W, Adeli K, Cheung RC. Atorvastatin treatment beneficially alters the lipoprotein profile and increases low-density lipoprotein particle diameter in patients with combined dyslipidemia and impaired fasting glucose/type 2 diabetes. Metabolism: Clinical and Experimental. 51: 334-42. PMID 11887170 DOI: 10.1053/Meta.2002.30510  0.301
2002 Rashid S, Barrett PH, Uffelman KD, Watanabe T, Adeli K, Lewis GF. Lipolytically modified triglyceride-enriched HDLs are rapidly cleared from the circulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 483-7. PMID 11884294 DOI: 10.1161/Hq0302.105374  0.324
2002 Taghibiglou C, Van Iderstine SC, Kulinski A, Rudy D, Adeli K. Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. Biochemical Pharmacology. 63: 349-60. PMID 11853686 DOI: 10.1016/S0006-2952(01)00918-2  0.323
2001 Adeli K, Taghibiglou C, Van Iderstine SC, Lewis GF. Mechanisms of hepatic very low-density lipoprotein overproduction in insulin resistance. Trends in Cardiovascular Medicine. 11: 170-6. PMID 11597827 DOI: 10.1016/S1050-1738(01)00084-6  0.368
2000 Macri J, Kazemian P, Kulinski A, Rudy D, Aiton A, Thibert RJ, Adeli K. Translocational status of ApoB in the presence of an inhibitor of microsomal triglyceride transfer protein. Biochemical and Biophysical Research Communications. 276: 1035-47. PMID 11027587 DOI: 10.1006/Bbrc.2000.3509  0.308
2000 Taghibiglou C, Carpentier A, Van Iderstine SC, Chen B, Rudy D, Aiton A, Lewis GF, Adeli K. Mechanisms of hepatic very low density lipoprotein overproduction in insulin resistance. Evidence for enhanced lipoprotein assembly, reduced intracellular ApoB degradation, and increased microsomal triglyceride transfer protein in a fructose-fed hamster model. The Journal of Biological Chemistry. 275: 8416-25. PMID 10722675 DOI: 10.1074/Jbc.275.12.8416  0.383
2000 Mangaloglu L, Van-Iderstine S, Chen B, Taghibiglou C, Cheung R, Adeli K. Effect of atorvastatin (Lipitor™) on VLDL-APOB and VLDL-triglyceride overproduction in vivo in an insulin resistant hamster model Clinical Biochemistry. 33: 233. DOI: 10.1016/S0021-9150(00)80202-6  0.322
2000 Taghibiglou C, Van-Iderstine S, Chen B, Adeli K. Molecular mechanisms of hepatic insulin resistance in a fructose-fed/insulin resistant hamster model Clinical Biochemistry. 33: 240. DOI: 10.1016/S0009-9120(00)00129-6  0.312
2000 Pontrelli L, Cheung R, Parris W, Adeli K. Effect of atorvastatin on hepatic production of atherogenic lipoproteins in patients with insulin resistance syndrome/metabolic syndrome X Clinical Biochemistry. 33: 236. DOI: 10.1016/S0009-9120(00)00117-X  0.309
1998 Mohammadi A, Macri J, Newton R, Romain T, Dulay D, Adeli K. Effects of atorvastatin on the intracellular stability and secretion of apolipoprotein B in HepG2 cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 783-93. PMID 9598838 DOI: 10.1161/01.Atv.18.5.783  0.313
1993 Ogbonna G, Theriault A, Adeli K. Hormonal regulation of human apolipoprotein E gene expression in HepG2 cells. The International Journal of Biochemistry. 25: 635-40. PMID 8349006 DOI: 10.1016/0020-711X(93)90347-H  0.322
1985 Robert LS, Adeli K, Altosaar I. Homology among 3S and 7S Globulins from Cereals and Pea. Plant Physiology. 78: 812-6. PMID 16664331 DOI: 10.1104/Pp.78.4.812  0.47
1984 Adeli K, Allan-Wojtas P, Altosaar I. Intracellular transport and posttranslational cleavage of oat globulin precursors. Plant Physiology. 76: 16-20. PMID 16663789 DOI: 10.1104/Pp.76.1.16  0.478
1984 Adeli K, Altosaar I. Characterization of oat vicilin-like polypeptides. Plant Physiology. 75: 225-7. PMID 16663577 DOI: 10.1104/Pp.75.1.225  0.474
1984 Adeli K, Altosaar I. Compartmentalization of seed reserve proteins. Proposed discriminatory factors Febs Letters. 178: 193-198. DOI: 10.1016/0014-5793(84)80599-2  0.479
1983 Adeli K, Altosaar I. Role of endoplasmic reticulum in biosynthesis of oat globulin precursors. Plant Physiology. 73: 949-55. PMID 16663349 DOI: 10.1104/Pp.73.4.949  0.481
1983 Garson K, Matlashewski GJ, Adeli K, Robert LS, Altosaar I. Isolation of intact polysomes from mechanically dehulled developing grain. Analytical Biochemistry. 134: 512-6. PMID 6650835 DOI: 10.1016/0003-2697(83)90332-9  0.48
1983 Fabijanski S, Matlashewski G, Adeli K, Garson RK, Altosaar I. Globulin Storage Protein Genes in Cereals. Messenger RNA, Biosynthesis and cDNA Cloning Canadian Institute of Food Science and Technology Journal. 16: xii-xiii. DOI: 10.1016/S0315-5463(83)72116-4  0.458
1982 Matlashewski GJ, Adeli K, Altosaar I, Shewry PR, Miflin BJ. In vitro synthesis of oat globulin Febs Letters. 145: 208-212. DOI: 10.1016/0014-5793(82)80169-5  0.478
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