| Year |
Citation |
Score |
| 2021 |
Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, ... ... Overkleeft H, et al. The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses. Immunity. 54: 387. PMID 33567263 DOI: 10.1016/j.immuni.2021.01.016 |
0.406 |
|
| 2020 |
Jongsma MLM, de Waard AA, Raaben M, Zhang T, Cabukusta B, Platzer R, Blomen VA, Xagara A, Verkerk T, Bliss S, Kong X, Gerke C, Janssen L, Stickel E, Holst S, ... ... Overkleeft H, et al. The SPPL3-Defined Glycosphingolipid Repertoire Orchestrates HLA Class I-Mediated Immune Responses. Immunity. PMID 33271119 DOI: 10.1016/j.immuni.2020.11.003 |
0.47 |
|
| 2020 |
Qiao X, van der Zanden SY, Wander DPA, Borràs DM, Song JY, Li X, van Duikeren S, van Gils N, Rutten A, van Herwaarden T, van Tellingen O, Giacomelli E, Bellin M, Orlova V, Tertoolen LGJ, ... ... Overkleeft HS, et al. Uncoupling DNA damage from chromatin damage to detoxify doxorubicin. Proceedings of the National Academy of Sciences of the United States of America. PMID 32554494 DOI: 10.1073/Pnas.1922072117 |
0.479 |
|
| 2020 |
McGregor N, Artola M, Nin-Hill A, Linzel D, Haon M, Reijngoud J, Ram AFJ, Rosso MN, van der Marel GA, Codée JDC, van Wezel GP, Berrin JG, Rovira C, Overkleeft HS, Davies GJ. Rational Design of Mechanism-Based Inhibitors and Activity-Based Probes for the Identification of Retaining α-L-Arabinofuranosidases. Journal of the American Chemical Society. PMID 32053363 DOI: 10.1021/Jacs.9B11351 |
0.322 |
|
| 2019 |
Baggelaar MP, den Dulk H, Florea BI, Fazio D, Bernab Ograve N, Raspa M, Janssen APA, Scavizzi F, Barboni B, Overkleeft HS, Maccarrone M, van der Stelt M. ABHD2 inhibitor identified by activity-based protein profiling reduces acrosome reaction. Acs Chemical Biology. PMID 31525885 DOI: 10.1021/Acschembio.9B00640 |
0.377 |
|
| 2019 |
Grimm SH, Gagestein B, Keijzer JF, Liu N, Wijdeven RH, Lenselink EB, Tuin AW, van den Nieuwendijk AMCH, van Westen GJP, van Boeckel CAA, Overkleeft HS, Neefjes J, van der Stelt M. Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors. Bioorganic & Medicinal Chemistry. PMID 30661740 DOI: 10.1016/J.Bmc.2019.01.006 |
0.462 |
|
| 2019 |
Schroder SP, Boer C, McGregor NGS, Rowland RJ, Moroz O, Blagova E, Reijngoud J, Rovira C, Wezel GPv, Ram AFJ, Florea BI, Marel GAvd, Codee JDC, Wilson KS, Wu L, ... ... Overkleeft H, et al. Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes Acs Nano. DOI: 10.2210/Pdb6Q8M/Pdb |
0.308 |
|
| 2018 |
Rugen MD, Vernet MMJL, Hantouti L, Soenens A, Andriotis VME, Rejzek M, Brett P, van den Berg RJBHN, Aerts JMFG, Overkleeft HS, Field RA. A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals. Scientific Reports. 8: 16421. PMID 30401902 DOI: 10.1038/S41598-018-34749-1 |
0.307 |
|
| 2018 |
van Rooden EJ, Kohsiek M, Kreekel R, van Esbroeck ACM, van den Nieuwendijk AMCH, Janssen APA, van den Berg RJBHN, Overkleeft HS, van der Stelt M. Design and Synthesis of Quenched Activity-based Probes for Diacylglycerol Lipase and α,β-Hydrolase Domain Containing Protein 6. Chemistry, An Asian Journal. PMID 29901868 DOI: 10.1002/Asia.201800452 |
0.345 |
|
| 2018 |
Husaini AM, Morimoto K, Chandrasekar B, Kelly S, Kaschani F, Palmero D, Jiang J, Kaiser M, Ahrazem O, Overkleeft HS, van der Hoorn RAL. Multiplex fluorescent, activity-based protein profiling identifies active α-glycosidases and other hydrolases in plants. Plant Physiology. PMID 29555787 DOI: 10.1104/Pp.18.00250 |
0.312 |
|
| 2017 |
Deng H, van der Wel T, van den Berg RJBHN, van den Nieuwendijk AMCH, Janssen FJ, Baggelaar MP, Overkleeft HS, van der Stelt M. Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitors. Medchemcomm. 8: 982-988. PMID 30108813 DOI: 10.1039/C7Md00029D |
0.348 |
|
| 2017 |
Misas-Villamil JC, van der Burgh AM, Grosse-Holz F, Bach-Pages M, Kovács J, Kaschani F, Schilasky S, Emon AE, Ruben M, Kaiser M, Overkleeft HS, van der Hoorn RA. Subunit-selective proteasome activity profiling uncovers uncoupled proteasome subunit activities during bacterial infections. The Plant Journal : For Cell and Molecular Biology. PMID 28117509 DOI: 10.1111/Tpj.13494 |
0.325 |
|
| 2016 |
Kallemeijn W, Scheij S, Voorn-Brouwer TM, Witte MD, Verhoek M, Overkleeft HS, Boot RG, Aerts JM. Endo-β-glucosidase tag allowing dual detection of fusion proteins by fluorescent mechanism-based probes and activity measurement. Chembiochem : a European Journal of Chemical Biology. PMID 27383447 DOI: 10.1002/Cbic.201600312 |
0.316 |
|
| 2016 |
Stolze SC, Liu N, Wijdeven RH, Tuin AW, van den Nieuwendijk AM, Florea BI, van der Stelt M, van der Marel GA, Neefjes JJ, Overkleeft HS. Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes. Molecular Biosystems. PMID 27138522 DOI: 10.1039/c6mb00257a |
0.449 |
|
| 2016 |
Caner S, Zhang X, Jiang J, Chen HM, Nguyen NT, Overkleeft H, Brayer GD, Withers SG. Glucosyl Epi-cyclophellitol Allows Mechanism- Based Inactivation and Structural Analysis of Human Pancreatic Alpha-Amylase. Febs Letters. PMID 27000970 DOI: 10.1002/1873-3468.12143 |
0.323 |
|
| 2016 |
Banno A, Garcia DA, van Baarsel ED, Metz PJ, Fisch K, Widjaja CE, Kim SH, Lopez J, Chang AN, Geurink PP, Florea BI, Overkleeft HS, Ovaa H, Bui JD, Yang J, et al. Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. Oncotarget. PMID 26930717 DOI: 10.18632/Oncotarget.7596 |
0.311 |
|
| 2014 |
Ghisaidoobe AT, van den Berg RJ, Butt SS, Strijland A, Donker-Koopman WE, Scheij S, van den Nieuwendijk AM, Koomen GJ, van Loevezijn A, Leemhuis M, Wennekes T, van der Stelt M, van der Marel GA, van Boeckel CA, Aerts JM, ... Overkleeft HS, et al. Identification and development of biphenyl substituted iminosugars as improved dual glucosylceramide synthase/neutral glucosylceramidase inhibitors. Journal of Medicinal Chemistry. 57: 9096-104. PMID 25250725 DOI: 10.1021/jm501181z |
0.551 |
|
| 2014 |
Willems LI, Jiang J, Li KY, Witte MD, Kallemeijn WW, Beenakker TJ, Schröder SP, Aerts JM, van der Marel GA, Codée JD, Overkleeft HS. From covalent glycosidase inhibitors to activity-based glycosidase probes. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 10864-72. PMID 25100671 DOI: 10.1002/Chem.201404014 |
0.393 |
|
| 2014 |
Li H, van der Linden WA, Verdoes M, Florea BI, McAllister FE, Govindaswamy K, Elias JE, Bhanot P, Overkleeft HS, Bogyo M. Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probes. Acs Chemical Biology. 9: 1869-76. PMID 24918547 DOI: 10.1021/Cb5001263 |
0.473 |
|
| 2014 |
van Kasteren SI, Overkleeft H, Ovaa H, Neefjes J. Chemical biology of antigen presentation by MHC molecules Current Opinion in Immunology. 26: 21-31. PMID 24556397 DOI: 10.1016/J.Coi.2013.10.005 |
0.507 |
|
| 2012 |
Stolze SC, Deu E, Kaschani F, Li N, Florea BI, Richau KH, Colby T, van der Hoorn RA, Overkleeft HS, Bogyo M, Kaiser M. The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains. Chemistry & Biology. 19: 1546-55. PMID 23261598 DOI: 10.1016/J.Chembiol.2012.09.020 |
0.519 |
|
| 2012 |
Richau KH, Kaschani F, Verdoes M, Pansuriya TC, Niessen S, Stüber K, Colby T, Overkleeft HS, Bogyo M, Van der Hoorn RA. Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics. Plant Physiology. 158: 1583-99. PMID 22371507 DOI: 10.1104/Pp.112.194001 |
0.548 |
|
| 2012 |
Eldering E, Geest CR, de Rooij MF, Liu N, Florea BI, Van Oers MH, Overkleeft HS, Spaargaren M, Kater AP. Mapping the Targets of Dasatinib in Chronic Lymphocytic Leukemia Reveals Distinct Roles for Abl and Btk in Drug Resistance and Adhesion, and Explains Clinical Effects On Lymph Node Reduction Blood. 120: 3900-3900. DOI: 10.1182/Blood.V120.21.3900.3900 |
0.321 |
|
| 2011 |
Kessler JH, Khan S, Seifert U, Le Gall S, Chow KM, Paschen A, Bres-Vloemans SA, De Ru A, Van Montfoort N, Franken KLMC, Benckhuijsen WE, Brooks JM, Van Hall T, Ray K, Mulder A, ... ... Overkleeft HS, et al. Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes Nature Immunology. 12: 45-53. PMID 21151101 DOI: 10.1038/Ni.1974 |
0.52 |
|
| 2011 |
Kolodziejek I, Misas-Villamil JC, Kaschani F, Clerc J, Gu C, Krahn D, Niessen S, Verdoes M, Willems LI, Overkleeft HS, Kaiser M, van der Hoorn RA. Proteasome activity imaging and profiling characterizes bacterial effector syringolin A. Plant Physiology. 155: 477-89. PMID 21045122 DOI: 10.1104/Pp.110.163733 |
0.345 |
|
| 2011 |
Kraus M, Florea B, Bader J, Li N, Geurink P, van der Linden W, Overkleeft HS, Driessen C. Selective Inhibition of the proteasome's β2 Catalytic Subunit Alone Does Not Induce Cytotoxicity, but Resensitizes Bortezomib-Refractory Myeloma Cells for Bortezomib Treatment Blood. 118: 2915-2915. DOI: 10.1182/Blood.V118.21.2915.2915 |
0.303 |
|
| 2010 |
Gu C, Kolodziejek I, Misas-Villamil J, Shindo T, Colby T, Verdoes M, Richau KH, Schmidt J, Overkleeft HS, van der Hoorn RA. Proteasome activity profiling: a simple, robust and versatile method revealing subunit-selective inhibitors and cytoplasmic, defense-induced proteasome activities. The Plant Journal : For Cell and Molecular Biology. 62: 160-70. PMID 20042019 DOI: 10.1111/J.1365-313X.2009.04122.X |
0.351 |
|
| 2009 |
Hillaert U, Verdoes M, Florea BI, Saragliadis A, Saragliadis A, Habets KL, Kuiper J, Van Calenbergh S, Ossendorp F, van der Marel GA, Driessen C, Overkleeft HS. Receptor-mediated targeting of cathepsins in professional antigen presenting cells. Angewandte Chemie (International Ed. in English). 48: 1629-32. PMID 19156780 DOI: 10.1002/Anie.200805529 |
0.304 |
|
| 2009 |
Khan S, Weterings JJ, Britten CM, de Jong AR, Graafland D, Melief CJ, van der Burg SH, van der Marel G, Overkleeft HS, Filippov DV, Ossendorp F. Chirality of TLR-2 ligand Pam3CysSK4 in fully synthetic peptide conjugates critically influences the induction of specific CD8+ T-cells. Molecular Immunology. 46: 1084-91. PMID 19027958 DOI: 10.1016/J.Molimm.2008.10.006 |
0.308 |
|
| 2008 |
Kuijl C, Tuin AW, Overkleeft H, Neefjes J. Reciprocal chemical genetics for swift lead and target identification Molecular Biosystems. 4: 1001-1008. PMID 19082139 DOI: 10.1039/B803265N |
0.463 |
|
| 2007 |
Kuijl C, Savage NDL, Marsman M, Tuin AW, Janssen L, Egan DA, Ketema M, Van Den Nieuwendijk R, Van Den Eeden SJF, Geluk A, Poot A, Van Der Marel G, Beijersbergen RL, Overkleeft H, Ottenhoff THM, et al. Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1 Nature. 450: 725-730. PMID 18046412 DOI: 10.1038/Nature06345 |
0.494 |
|
| 2007 |
Khan S, Bijker MS, Weterings JJ, Tanke HJ, Adema GJ, van Hall T, Drijfhout JW, Melief CJ, Overkleeft HS, van der Marel GA, Filippov DV, van der Burg SH, Ossendorp F. Distinct uptake mechanisms but similar intracellular processing of two different toll-like receptor ligand-peptide conjugates in dendritic cells. The Journal of Biological Chemistry. 282: 21145-59. PMID 17462991 DOI: 10.1074/Jbc.M701705200 |
0.308 |
|
| 2007 |
Agrawal PR, Hofmann MW, Meeuwenoord NJ, Filippov DV, Stalz H, Hulsbergen F, Langosch D, Overkleeft HS, De Groot H. Solid-phase synthesis and purification of a set of uniformly 13C, 15N labelled de novo designed membrane fusogenic peptides. Journal of Peptide Science : An Official Publication of the European Peptide Society. 13: 75-80. PMID 17121421 DOI: 10.1002/Psc.786 |
0.305 |
|
| 2007 |
Boot RG, Verhoek M, Donker-Koopman W, Strijland A, van Marle J, Overkleeft HS, Wennekes T, Aerts JM. Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2. The Journal of Biological Chemistry. 282: 1305-12. PMID 17105727 DOI: 10.1074/Jbc.M610544200 |
0.343 |
|
| 2006 |
Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, ... ... Overkleeft HS, et al. A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo. Chemistry & Biology. 13: 1217-26. PMID 17114003 DOI: 10.1016/J.Chembiol.2006.09.013 |
0.518 |
|
| 2005 |
Borodovsky A, Ovaa H, Meester WJ, Venanzi ES, Bogyo MS, Hekking BG, Ploegh HL, Kessler BM, Overkleeft HS. Small-molecule inhibitors and probes for ubiquitin- and ubiquitin-like-specific proteases. Chembiochem : a European Journal of Chemical Biology. 6: 287-91. PMID 15651044 DOI: 10.1002/Cbic.200400236 |
0.564 |
|
| 2004 |
van Swieten PF, Maehr R, van den Nieuwendijk AM, Kessler BM, Reich M, Wong CS, Kalbacher H, Leeuwenburgh MA, Driessen C, van der Marel GA, Ploegh HL, Overkleeft HS. Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases. Bioorganic & Medicinal Chemistry Letters. 14: 3131-4. PMID 15149659 DOI: 10.1016/J.Bmcl.2004.04.046 |
0.66 |
|
| 2003 |
Kocks C, Maehr R, Overkleeft HS, Wang EW, Iyer LK, Lennon-Dumenil AM, Ploegh HL, Kessler BM. Functional proteomics of the active cysteine protease content in Drosophila S2 cells. Molecular & Cellular Proteomics : McP. 2: 1188-97. PMID 13130081 DOI: 10.1074/Mcp.M300067-Mcp200 |
0.681 |
|
| 2003 |
Ovaa H, van Swieten PF, Kessler BM, Leeuwenburgh MA, Fiebiger E, van den Nieuwendijk AM, Galardy PJ, van der Marel GA, Ploegh HL, Overkleeft HS. Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy. Angewandte Chemie (International Ed. in English). 42: 3626-9. PMID 12916032 DOI: 10.1002/Anie.200351314 |
0.412 |
|
| 2003 |
Aguilera B, Ghauharali-van der Vlugt K, Helmond MT, Out JM, Donker-Koopman WE, Groener JE, Boot RG, Renkema GH, van der Marel GA, van Boom JH, Overkleeft HS, Aerts JM. Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase. The Journal of Biological Chemistry. 278: 40911-6. PMID 12890686 DOI: 10.1074/Jbc.M301804200 |
0.339 |
|
| 2003 |
Kisselev AF, Garcia-Calvo M, Overkleeft HS, Peterson E, Pennington MW, Ploegh HL, Thornberry NA, Goldberg AL. The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. The Journal of Biological Chemistry. 278: 35869-77. PMID 12815064 DOI: 10.1074/Jbc.M303725200 |
0.4 |
|
| 2002 |
Lennon-Duménil AM, Bakker AH, Maehr R, Fiebiger E, Overkleeft HS, Rosemblatt M, Ploegh HL, Lagaudrière-Gesbert C. Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation. The Journal of Experimental Medicine. 196: 529-40. PMID 12186844 DOI: 10.1084/jem.20020327 |
0.671 |
|
| 2001 |
Borodovsky A, Kessler BM, Casagrande R, Overkleeft HS, Wilkinson KD, Ploegh HL. A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14. The Embo Journal. 20: 5187-96. PMID 11566882 DOI: 10.1093/Emboj/20.18.5187 |
0.45 |
|
| 2001 |
Kessler BM, Tortorella D, Altun M, Kisselev AF, Fiebiger E, Hekking BG, Ploegh HL, Overkleeft HS. Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits. Chemistry & Biology. 8: 913-29. PMID 11564559 DOI: 10.1016/S1074-5521(01)00069-2 |
0.458 |
|
| 2001 |
Lennon-Duménil AM, Roberts RA, Valentijn K, Driessen C, Overkleeft HS, Erickson A, Peters PJ, Bikoff E, Ploegh HL, Wolf Bryant P. The p41 isoform of invariant chain is a chaperone for cathepsin L. The Embo Journal. 20: 4055-64. PMID 11483509 DOI: 10.1093/Emboj/20.15.4055 |
0.398 |
|
| 1998 |
Overkleeft HS, Renkema GH, Neele J, Vianello P, Hung IO, Strijland A, van der Burg AM, Koomen GJ, Pandit UK, Aerts JM. Generation of specific deoxynojirimycin-type inhibitors of the non-lysosomal glucosylceramidase. The Journal of Biological Chemistry. 273: 26522-7. PMID 9756888 DOI: 10.1074/jbc.273.41.26522 |
0.65 |
|
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