| Year |
Citation |
Score |
| 2021 |
Inan S, Chen X, Eisenstein EM, Meissler JJ, Geller EB, Tallarida C, Watson M, Doura M, Barrett JE, Cowan A, Rawls SM, Adler MW, Eisenstein TK. Chemokine receptor antagonists enhance morphine's antinociceptive effect but not respiratory depression. Life Sciences. 120014. PMID 34619167 DOI: 10.1016/j.lfs.2021.120014 |
0.453 |
|
| 2021 |
Inan S, Dun NJ, Cowan A. Antipruritic Effect of Nalbuphine, a Kappa Opioid Receptor Agonist, in Mice: A Pan Antipruritic. Molecules (Basel, Switzerland). 26. PMID 34576988 DOI: 10.3390/molecules26185517 |
0.377 |
|
| 2020 |
Inan S, Cowan A. Antipruritic Effects of Kappa Opioid Receptor Agonists: Evidence from Rodents to Humans. Handbook of Experimental Pharmacology. PMID 33296031 DOI: 10.1007/164_2020_420 |
0.373 |
|
| 2020 |
Eisenstein TK, Chen X, Inan S, Meissler JJ, Tallarida CS, Geller EB, Rawls SM, Cowan A, Adler MW. Chemokine Receptor Antagonists in Combination with Morphine as a Novel Strategy for Opioid Dose Reduction in Pain Management. Military Medicine. 185: 130-135. PMID 32074321 DOI: 10.1093/Milmed/Usz320 |
0.544 |
|
| 2019 |
Inan S, Huerta AT, Jensen LE, Dun NJ, Cowan A. Nalbuphine, a kappa opioid receptor agonist and mu opioid receptor antagonist attenuates pruritus, decreases IL-31, and increases IL-10 in mice with contact dermatitis. European Journal of Pharmacology. 172702. PMID 31568781 DOI: 10.1016/J.Ejphar.2019.172702 |
0.47 |
|
| 2019 |
Chen X, Cowan A, Inan S, Geller EB, Meissler JJ, Rawls SM, Tallarida RJ, Tallarida CS, Watson MN, Adler MW, Eisenstein TK. Opioid-Sparing Effects of Cannabinoids on Morphine Analgesia: Participation of CB1 and CB2 Receptors. British Journal of Pharmacology. PMID 31218677 DOI: 10.1111/Bph.14769 |
0.516 |
|
| 2019 |
Inan S, Watson MN, Doura M, Tallarida CS, Meissler JJ, Chen X, Geller EB, Cowan A, Rawls SM, Eisenstein TK, Adler MW. Chemokine receptor antagonists enhance the antinociceptive activity of oxycodone and meperidine on incisional pain in rats. British Journal of Anaesthesia. PMID 30916010 DOI: 10.1016/J.Bja.2019.01.021 |
0.358 |
|
| 2018 |
Inan S, Eisenstein TK, Watson MN, Doura M, Meissler JJ, Tallarida CS, Chen X, Geller EB, Rawls SM, Cowan A, Adler MW. Co-Administration of Chemokine Receptor Antagonists with Morphine Potentiates Morphine's Analgesic Effect on Incisional Pain in Rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 30249618 DOI: 10.1124/Jpet.118.252890 |
0.532 |
|
| 2018 |
Liu JJ, Chiu YT, DiMattio KM, Chen C, Huang P, Gentile TA, Muschamp JW, Cowan A, Mann M, Liu-Chen LY. Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30082888 DOI: 10.1038/S41386-018-0155-0 |
0.436 |
|
| 2016 |
Cowan A, Sarabia-Estrada R, Wilkerson G, McKnight P, Guarnieri M. Lack of adverse effects during a target animal safety trial of extended-release buprenorphine in Fischer 344 rats. Lab Animal. 45: 28-34. PMID 26684956 DOI: 10.1038/Laban.745 |
0.39 |
|
| 2015 |
Cowan A, Lyu RM, Chen YH, Dun SL, Chang JK, Dun NJ. Phoenixin: a candidate pruritogen in the mouse. Neuroscience. PMID 26415767 DOI: 10.1016/J.Neuroscience.2015.09.055 |
0.388 |
|
| 2015 |
Cowan A, Kehner GB, Inan S. Targeting Itch with Ligands Selective for κ Opioid Receptors. Handbook of Experimental Pharmacology. 226: 291-314. PMID 25861786 DOI: 10.1007/978-3-662-44605-8_16 |
0.767 |
|
| 2015 |
Zhang Y, Dun SL, Chen YH, Luo JJ, Cowan A, Dun NJ. Scratching activates microglia in the mouse spinal cord. Journal of Neuroscience Research. 93: 466-74. PMID 25354468 DOI: 10.1002/Jnr.23501 |
0.345 |
|
| 2014 |
Cowan A, Raffa RB, Tallarida CS, Tallarida RJ, Christoph T, Schröder W, Tzschentke TM. Lack of synergistic interaction between the two mechanisms of action of tapentadol in gastrointestinal transit. European Journal of Pain (London, England). 18: 1148-56. PMID 24574066 DOI: 10.1002/J.1532-2149.2014.00461.X |
0.418 |
|
| 2014 |
Dimattio KM, Yakovleva TV, Aldrich JV, Cowan A, Liu-Chen LY. Zyklophin, a short-acting kappa opioid antagonist, induces scratching in mice. Neuroscience Letters. 563: 155-9. PMID 24503508 DOI: 10.1016/J.Neulet.2014.01.022 |
0.512 |
|
| 2011 |
Palma J, Cowan A, Geller EB, Adler MW, Benamar K. Differential antinociceptive effects of buprenorphine and methadone in the presence of HIV-gp120. Drug and Alcohol Dependence. 118: 497-9. PMID 21600706 DOI: 10.1016/J.Drugalcdep.2011.04.010 |
0.399 |
|
| 2011 |
Kim J, Cowan A, Lisek R, Raymondi N, Rosenthal A, Hirsch DD, Rawls SM. Icilin-evoked behavioral stimulation is attenuated by alphaâ‚‚-adrenoceptor activation. Brain Research. 1384: 110-7. PMID 21315691 DOI: 10.1016/J.Brainres.2011.02.002 |
0.481 |
|
| 2011 |
Inan S, Dun NJ, Cowan A. Investigation of gastrin-releasing peptide as a mediator for 5'-guanidinonaltrindole-induced compulsive scratching in mice. Peptides. 32: 286-92. PMID 21126550 DOI: 10.1016/J.Peptides.2010.11.022 |
0.554 |
|
| 2011 |
Benamar K, Palma J, Cowan A, Geller EB, Adler MW. Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1α/CXCL12 in the brain. Drug and Alcohol Dependence. 114: 246-8. PMID 21112161 DOI: 10.1016/J.Drugalcdep.2010.08.015 |
0.504 |
|
| 2010 |
Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Molecular Pharmacology. 78: 560-8. PMID 20826425 DOI: 10.1124/Mol.110.066746 |
0.375 |
|
| 2010 |
Tallarida RJ, Cowan A, Raffa RB. On deriving the dose-effect relation of an unknown second component: an example using buprenorphine preclinical data. Drug and Alcohol Dependence. 109: 126-9. PMID 20061095 DOI: 10.1016/J.Drugalcdep.2009.12.014 |
0.372 |
|
| 2009 |
Huang P, Liu-Chen LY, Unterwald EM, Cowan A. Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice. Neuroscience Letters. 465: 66-70. PMID 19733208 DOI: 10.1016/J.Neulet.2009.08.073 |
0.374 |
|
| 2009 |
Inan S, Dun NJ, Cowan A. Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. European Journal of Pharmacology. 616: 141-6. PMID 19549515 DOI: 10.1016/J.Ejphar.2009.06.026 |
0.382 |
|
| 2009 |
Inan S, Dun NJ, Cowan A. Nalfurafine prevents 5'-guanidinonaltrindole- and compound 48/80-induced spinal c-fos expression and attenuates 5'-guanidinonaltrindole-elicited scratching behavior in mice. Neuroscience. 163: 23-33. PMID 19524022 DOI: 10.1016/J.Neuroscience.2009.06.016 |
0.468 |
|
| 2009 |
Werkheiser J, Cowan A, Gomez T, Henry C, Parekh S, Chau S, Baron DA, Rawls SM. Icilin-induced wet-dog shakes in rats are dependent on NMDA receptor activation and nitric oxide production. Pharmacology, Biochemistry, and Behavior. 92: 543-8. PMID 19248800 DOI: 10.1016/J.Pbb.2009.02.005 |
0.802 |
|
| 2009 |
Inan S, Lee DY, Liu-Chen LY, Cowan A. Comparison of the diuretic effects of chemically diverse kappa opioid agonists in rats: nalfurafine, U50,488H, and salvinorin A. Naunyn-Schmiedeberg's Archives of Pharmacology. 379: 263-70. PMID 18925386 DOI: 10.1007/S00210-008-0358-8 |
0.511 |
|
| 2008 |
Ding Z, Cowan A, Rawls SM. 5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats. Neuroscience Letters. 430: 191-6. PMID 18155835 DOI: 10.1016/J.Neulet.2007.10.033 |
0.562 |
|
| 2008 |
Wang Y, Chen Y, Xu W, Lee DY, Ma Z, Rawls SM, Cowan A, Liu-Chen LY. 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. The Journal of Pharmacology and Experimental Therapeutics. 324: 1073-83. PMID 18089845 DOI: 10.1124/Jpet.107.132142 |
0.417 |
|
| 2008 |
Radzievsky AA, Gordiienko OV, Alekseev S, Szabo I, Cowan A, Ziskin MC. Electromagnetic millimeter wave induced hypoalgesia: Frequency dependence and involvement of endogenous opioids Bioelectromagnetics. 29: 284-295. PMID 18064600 DOI: 10.1002/Bem.20389 |
0.411 |
|
| 2008 |
Ding Z, Gomez T, Werkheiser JL, Cowan A, Rawls SM. Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation. European Journal of Pharmacology. 578: 201-8. PMID 17976579 DOI: 10.1016/J.Ejphar.2007.09.030 |
0.792 |
|
| 2008 |
Ung D, Li H, Cowan A, Parkman HP, Nagar S. T1309 Evaluation of Interactions Between Morphine and Metoclopramide Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)62465-8 |
0.342 |
|
| 2007 |
Cowan A. Buprenorphine: the basic pharmacology revisited. Journal of Addiction Medicine. 1: 68-72. PMID 21768937 DOI: 10.1097/Adm.0B013E31806C9202 |
0.444 |
|
| 2007 |
Werkheiser JL, Rawls SM, Cowan A. Nalfurafine, the kappa opioid agonist, inhibits icilin-induced wet-dog shakes in rats and antagonizes glutamate release in the dorsal striatum. Neuropharmacology. 52: 925-30. PMID 17150231 DOI: 10.1016/J.Neuropharm.2006.10.010 |
0.818 |
|
| 2006 |
Ding Z, Cowan A, Tallarida R, Rawls SM. Capsaicin and nitric oxide synthase inhibitor interact to evoke a hypothermic synergy. Neuroscience Letters. 409: 41-6. PMID 17018247 DOI: 10.1016/J.Neulet.2006.09.018 |
0.573 |
|
| 2006 |
Werkheiser JL, Rawls SM, Cowan A. Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats. European Journal of Pharmacology. 547: 101-5. PMID 16945367 DOI: 10.1016/J.Ejphar.2006.07.026 |
0.842 |
|
| 2006 |
Inan S, Cowan A. Nalfurafine, a kappa opioid receptor agonist, inhibits scratching behavior secondary to cholestasis induced by chronic ethynylestradiol injections in rats. Pharmacology, Biochemistry, and Behavior. 85: 39-43. PMID 16919318 DOI: 10.1016/J.Pbb.2006.07.004 |
0.574 |
|
| 2006 |
Hummel M, Schroeder J, Liu-Chen LY, Cowan A, Unterwald EM. An antisense oligodeoxynucleotide to the mu opioid receptor attenuates cocaine-induced behavioral sensitization and reward in mice. Neuroscience. 142: 481-91. PMID 16893609 DOI: 10.1016/J.Neuroscience.2006.06.013 |
0.393 |
|
| 2006 |
Rawls SM, Ding Z, Cowan A. Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. Pharmacology, Biochemistry, and Behavior. 83: 508-16. PMID 16647109 DOI: 10.1016/J.Pbb.2006.03.011 |
0.666 |
|
| 2006 |
Werkheiser JL, Rawls SM, Cowan A. Icilin evokes a dose- and time-dependent increase in glutamate within the dorsal striatum of rats. Amino Acids. 30: 307-9. PMID 16622598 DOI: 10.1007/S00726-005-0306-6 |
0.81 |
|
| 2006 |
Rawls SM, Allebach C, Cowan A. Nitric oxide synthase mediates delta opioid receptor-induced hypothermia in rats. European Journal of Pharmacology. 536: 109-12. PMID 16566919 DOI: 10.1016/J.Ejphar.2006.02.044 |
0.516 |
|
| 2006 |
Feng P, Rahim RT, Cowan A, Liu-Chen LY, Peng X, Gaughan J, Meissler JJ, Adler MW, Eisenstein TK. Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit. European Journal of Pharmacology. 534: 250-7. PMID 16513108 DOI: 10.1016/J.Ejphar.2006.01.048 |
0.546 |
|
| 2006 |
Rawls SM, Cowan A. Modulation of delta opioid-evoked hypothermia in rats by WAY 100635 and fluoxetine. Neuroscience Letters. 398: 319-24. PMID 16483716 DOI: 10.1016/J.Neulet.2006.01.017 |
0.576 |
|
| 2005 |
Ding Z, Cowan A, Rawls SM. Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors. Brain Research. 1065: 147-51. PMID 16309633 DOI: 10.1016/J.Brainres.2005.10.026 |
0.652 |
|
| 2005 |
Inan S, Cowan A. Reduced kappa-opioid activity in a rat model of cholestasis. European Journal of Pharmacology. 518: 182-6. PMID 16054619 DOI: 10.1016/J.Ejphar.2005.06.025 |
0.482 |
|
| 2005 |
Rawls SM, Hewson JM, Inan S, Cowan A. Brain delta2 opioid receptors mediate SNC-80-evoked hypothermia in rats. Brain Research. 1049: 61-9. PMID 15936000 DOI: 10.1016/J.Brainres.2005.04.074 |
0.6 |
|
| 2005 |
Zhang N, Inan S, Inan S, Cowan A, Sun R, Wang JM, Rogers TJ, Caterina M, Oppenheim JJ. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. Proceedings of the National Academy of Sciences of the United States of America. 102: 4536-41. PMID 15764707 DOI: 10.1073/Pnas.0406030102 |
0.391 |
|
| 2005 |
Rawls SM, Ding Z, Gray AM, Cowan A. Peripheral kappa-opioid agonist, ICI 204448, evokes hypothermia in cold-exposed rats. Pharmacology. 74: 79-83. PMID 15687734 DOI: 10.1159/000083704 |
0.702 |
|
| 2005 |
Wang Y, Tang K, Inan S, Siebert D, Holzgrabe U, Lee DY, Huang P, Li JG, Cowan A, Liu-Chen LY. Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. The Journal of Pharmacology and Experimental Therapeutics. 312: 220-30. PMID 15383632 DOI: 10.1124/Jpet.104.073668 |
0.463 |
|
| 2004 |
Lutfy K, Cowan A. Buprenorphine: a unique drug with complex pharmacology. Current Neuropharmacology. 2: 395-402. PMID 18997874 DOI: 10.2174/1570159043359477 |
0.485 |
|
| 2004 |
Inan S, Cowan A. Kappa opioid agonists suppress chloroquine-induced scratching in mice. European Journal of Pharmacology. 502: 233-7. PMID 15476749 DOI: 10.1016/J.Ejphar.2004.09.010 |
0.547 |
|
| 2004 |
Zhang N, Inan S, Cowan A, Guler A, Sun R, Wang J, Rogers T, Caterina M, Oppenheim J. Arthritis Research & Therapy. 6: 16. DOI: 10.1186/Ar1350 |
0.405 |
|
| 2003 |
Rawls SM, Adler MW, Gaughan JP, Baron A, Geller EB, Cowan A. NMDA receptors modulate morphine-induced hyperthermia. Brain Research. 984: 76-83. PMID 12932841 DOI: 10.1016/S0006-8993(03)03093-2 |
0.569 |
|
| 2002 |
De Haven-Hudkins DL, Cowan A, Cortes Burgos L, Daubert JD, Cassel JA, DeHaven RN, Kehner GB, Kumar V. Antipruritic and antihyperalgesic actions of loperamide and analogs Life Sciences. 71: 2787-2796. PMID 12383884 DOI: 10.1016/S0024-3205(02)02102-1 |
0.776 |
|
| 2002 |
Rawls SM, Cowan A, Tallarida RJ, Geller EB, Adler MW. N-methyl-D-aspartate antagonists and WIN 55212-2 [4,5-dihydro-2-methyl-4(4-morpholinylmethyl)-1-(1-naphthalenyl-carbonyl)-6H-pyrrolo[3,2,1-i,j]quinolin-6-one], a cannabinoid agonist, interact to produce synergistic hypothermia. The Journal of Pharmacology and Experimental Therapeutics. 303: 395-402. PMID 12235276 DOI: 10.1124/Jpet.102.037473 |
0.482 |
|
| 2002 |
Radzievsky AA, Cowan A, Byrd C, Radzievsky AA, Ziskin MC. Single millimeter wave treatment does not impair gastrointestinal transit in mice. Life Sciences. 71: 1763-70. PMID 12151054 DOI: 10.1016/S0024-3205(02)01944-6 |
0.36 |
|
| 2002 |
Rahim RT, Adler MW, Meissler JJ, Cowan A, Rogers TJ, Geller EB, Eisenstein TK. Abrupt or precipitated withdrawal from morphine induces immunosuppression. Journal of Neuroimmunology. 127: 88-95. PMID 12044979 DOI: 10.1016/S0165-5728(02)00103-0 |
0.436 |
|
| 2002 |
Gopal S, Tzeng TB, Cowan A. Characterization of the pharmacokinetics of buprenorphine and norbuprenorphine in rats after intravenous bolus administration of buprenorphine. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 15: 287-93. PMID 11923061 DOI: 10.1016/S0928-0987(02)00009-X |
0.362 |
|
| 2001 |
Tomizawa M, Cowan A, Casida JE. Analgesic and toxic effects of neonicotinoid insecticides in mice. Toxicology and Applied Pharmacology. 177: 77-83. PMID 11708903 DOI: 10.1006/Taap.2001.9292 |
0.398 |
|
| 2001 |
Rahim RT, Meissler JJ, Cowan A, Rogers TJ, Geller EB, Gaughan J, Adler MW, Eisenstein TK. Administration of mu-, kappa- or delta2-receptor agonists via osmotic minipumps suppresses murine splenic antibody responses. International Immunopharmacology. 1: 2001-9. PMID 11606031 DOI: 10.1016/S1567-5769(01)00128-X |
0.561 |
|
| 2001 |
Peng X, Cebra JJ, Adler MW, Meissler JJ, Cowan A, Feng P, Eisenstein TK. Morphine inhibits mucosal antibody responses and TGF-beta mRNA in gut-associated lymphoid tissue following oral cholera toxin in mice. Journal of Immunology (Baltimore, Md. : 1950). 167: 3677-81. PMID 11564781 DOI: 10.4049/Jimmunol.167.7.3677 |
0.432 |
|
| 2001 |
Huang P, Kehner GB, Cowan A, Liu-Chen LY. Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist. The Journal of Pharmacology and Experimental Therapeutics. 297: 688-95. PMID 11303059 |
0.779 |
|
| 2000 |
Rojavin MA, Radzievsky AA, Cowan A, Ziskin MC. Pain relief caused by millimeter waves in mice: results of cold water tail flick tests. International Journal of Radiation Biology. 76: 575-579. PMID 10815639 DOI: 10.1080/095530000138592 |
0.338 |
|
| 1998 |
Rojavin MA, Cowan A, Radzievsky AA, Ziskin MC. Antipruritic effect of millimeter waves in mice: Evidence for opioid involvement Life Sciences. 63. PMID 9806220 DOI: 10.1016/S0024-3205(98)00436-6 |
0.448 |
|
| 1996 |
Cooper SA, Cowan A, Tallarida RJ, Hargreaves K, Roszkowski M, Jamali F, Borenstein M, Lucyk D, Fielding AF, Smith B, Feng D. The Analgesic Interaction of Misoprostol with Nonsteroidal Anti-Inflammatory Drugs. American Journal of Therapeutics. 3: 261-267. PMID 11862259 DOI: 10.1097/00045391-199604000-00002 |
0.339 |
|
| 1996 |
Chang AC, Cowan A, Takemori AE, Portoghese PS. Aspartic acid conjugates of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1(3-aminophenyl)-2-(1-pyrrolidi nyl) ethyl]acetamide: kappa opioid receptor agonists with limited access to the central nervous system. Journal of Medicinal Chemistry. 39: 4478-82. PMID 8893842 DOI: 10.1021/Jm960459X |
0.473 |
|
| 1996 |
Ryan RR, Taylor JE, Daniel JL, Cowan A. Pharmacological profiles of two bombesin analogues in cells transfected with human neuromedin B receptors. European Journal of Pharmacology. 306: 307-14. PMID 8813645 DOI: 10.1016/0014-2999(96)00223-3 |
0.352 |
|
| 1995 |
Parkman HP, Vozzelli MA, Pagano AP, Cowan A. Pharmacological analysis of receptors for bombesin-related peptides on guinea pig gallbladder smooth muscle. Regulatory Peptides. 52: 173-80. PMID 7800849 DOI: 10.1016/0167-0115(94)90051-5 |
0.403 |
|
| 1994 |
Cowan A. Involvement of kappa opioid receptors in the neuroadaptation of rats to buprenorphine Regulatory Peptides. 54: 69-70. DOI: 10.1016/0167-0115(94)90393-X |
0.559 |
|
| 1993 |
Wheeler-Aceto H, Cowan A. Naloxone causes apparent antinociception and pronociception simultaneously in the rat paw formalin test. European Journal of Pharmacology. 236: 193-199. PMID 8319750 DOI: 10.1016/0014-2999(93)90589-A |
0.511 |
|
| 1991 |
Wheeler-Aceto H, Cowan A. Buprenorphine and morphine cause antisiociception by different transduction mechanisms European Journal of Pharmacology. 195: 411-413. PMID 1907922 DOI: 10.1016/0014-2999(91)90485-9 |
0.442 |
|
| 1991 |
Wheeler-Aceto H, Cowan A. Standardization of the rat paw formalin test for the evaluation of analgesics. Psychopharmacology. 104: 35-44. PMID 1882002 DOI: 10.1007/Bf02244551 |
0.447 |
|
| 1991 |
Krevsky B, Cowan A, Maurer AH, Butt W, Fisher RS. Effects of selective opioid agonists on feline colonic transit. Life Sciences. 48: 1597-602. PMID 1850059 DOI: 10.1016/0024-3205(91)90285-J |
0.533 |
|
| 1991 |
Murray CW, Cowan A, Larson AA. Neurokinin and NMDA antagonists (but not a kainic acid antagonist) are antinociceptive in the mouse formalin model. Pain. 44: 179-85. PMID 1711193 DOI: 10.1016/0304-3959(91)90135-K |
0.377 |
|
| 1991 |
Liu-Chen LY, Li SX, Wheeler-Aceto H, Cowan A. Effects of intracerebroventricular beta-funaltrexamine on mu and delta opioid receptors in the rat: dichotomy between binding and antinociception. European Journal of Pharmacology. 203: 195-202. PMID 1666046 DOI: 10.1016/0014-2999(91)90715-3 |
0.4 |
|
| 1990 |
Wheeler-Aceto H, Porreca F, Cowan A. The rat paw formalin test: comparison of noxious agents Pain. 40: 229-238. PMID 2308768 DOI: 10.1016/0304-3959(90)90073-M |
0.345 |
|
| 1990 |
Murray CW, Cowan A. [D-Pen2, D-Pen5]enkephalin, the standard delta opioid agonist, induces morphine-like behaviors in mice. Psychopharmacology. 102: 425-6. PMID 2251341 DOI: 10.1007/Bf02244117 |
0.541 |
|
| 1990 |
Krevsky B, Fisher RS, Cowan A. Failure of (+)-naloxone to accelerate feline colonic transit. Experientia. 46: 217-9. PMID 2154387 DOI: 10.1007/Bf02027320 |
0.482 |
|
| 1990 |
Cowan A, Daniel JL, Ryan RR, Wheeler-Aceto H. Pharmacological profile of ICI 216140, a novel bombesin antagonist European Journal of Pharmacology. 183: 235-236. DOI: 10.1016/0014-2999(90)93078-5 |
0.422 |
|
| 1988 |
Cowan A. New bombesin antagonist shown to have 'encouraging profile'. Trends in Pharmacological Sciences. 9: 1-3. PMID 3245072 DOI: 10.1016/0165-6147(88)90227-1 |
0.335 |
|
| 1988 |
Murray CW, Porreca F, Cowan A. Methodological refinements to the mouse paw formalin test. An animal model of tonic pain. Journal of Pharmacological Methods. 20: 175-86. PMID 3221681 DOI: 10.1016/0160-5402(88)90078-2 |
0.375 |
|
| 1988 |
Wheeler H, Blackburn TP, Russell NJW, Cowan A. Effects of Lidocaine or Capsaicin on Scratching and Grooming Induced in Mice by Centrally or Peripherally Injected Bombesina Annals of the New York Academy of Sciences. 525: 433-434. DOI: 10.1111/J.1749-6632.1988.Tb38636.X |
0.33 |
|
| 1986 |
Koslo RJ, Vaught JL, Cowan A, Gmerek DE, Porreca F. Intrathecal morphine slows gastrointestinal transit in rats. European Journal of Pharmacology. 119: 243-6. PMID 3841514 DOI: 10.1016/0014-2999(85)90303-6 |
0.465 |
|
| 1986 |
Koslo RJ, Gmerek DE, Cowan A, Porreca F. Intrathecal bombesin-induced inhibition of gastrointestinal transit: requirement for an intact pituitary-adrenal axis. Regulatory Peptides. 14: 237-42. PMID 3755251 DOI: 10.1016/0167-0115(86)90006-6 |
0.324 |
|
| 1986 |
Cowan A, Khunawat P. Increased Urine Output by Rats after Intracerebroventricular Administration of Kappa Agonists Annals of the New York Academy of Sciences. 463: 174-176. DOI: 10.1111/J.1749-6632.1986.Tb21536.X |
0.429 |
|
| 1986 |
Cowan A, Gmerek DE. In-vivo studies on kappa opioid receptors Trends in Pharmacological Sciences. 7: 69-72. DOI: 10.1016/0165-6147(86)90257-9 |
0.56 |
|
| 1985 |
Gmerek DE, Cowan A. Pituitary-adrenal mediation of bombesin-induced inhibition of gastrointestinal transit in rats. Regulatory Peptides. 9: 299-304. PMID 6522645 DOI: 10.1016/0167-0115(84)90082-X |
0.351 |
|
| 1985 |
Gmerek DE, Ryan JP, Cowan A. Cross-tolerance between morphine- and bombesin-induced inhibition of intestinal transit in rats. European Journal of Pharmacology. 114: 175-80. PMID 4043225 DOI: 10.1016/0014-2999(85)90625-9 |
0.492 |
|
| 1985 |
Cowan A, Zhu XZ, Porreca F. Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin Neuropeptides. 5: 311-314. PMID 2987731 DOI: 10.1016/0143-4179(85)90015-0 |
0.592 |
|
| 1985 |
Pizziketti RJ, Pressman NS, Geller EB, Cowan A, Adler MW. Rat cold water tail-flick: a novel analgesic test that distinguishes opioid agonists from mixed agonist-antagonists. European Journal of Pharmacology. 119: 23-9. PMID 2867920 DOI: 10.1016/0014-2999(85)90317-6 |
0.53 |
|
| 1985 |
Vaught JL, Cowan A, Jacoby HI. Mu and delta, but not kappa, opioid agonists induce contractions of the canine small intestine in vivo. European Journal of Pharmacology. 109: 43-8. PMID 2859995 DOI: 10.1016/0014-2999(85)90537-0 |
0.532 |
|
| 1985 |
Cowan A, Khunawat P, Zhu XZ, Gmerek DE. IV. Effects of bombesin on behavior Life Sciences. 37: 135-145. PMID 2409426 DOI: 10.1016/0024-3205(85)90416-3 |
0.413 |
|
| 1984 |
Tortella FC, Cowan A, Holaday JW. Pituitary opioid involvement in ECS-postictal electrogenesis and behavioral depression in rats. Peptides. 5: 115-8. PMID 6538682 DOI: 10.1016/0196-9781(84)90060-3 |
0.465 |
|
| 1984 |
Tortella FC, Cowan A, Adler MW. Studies on the excitatory and inhibitory influence of intracerebroventricularly injected opioids on seizure thresholds in rats. Neuropharmacology. 23: 749-54. PMID 6472579 DOI: 10.1016/0028-3908(84)90107-2 |
0.441 |
|
| 1984 |
Tortella FC, Robles LE, Holaday JW, Cowan A. ICI 154,129, a δ-opioid receptor antagonist raises seizure threshold in rats European Journal of Pharmacology. 97: 141-144. PMID 6321207 DOI: 10.1016/0014-2999(84)90523-5 |
0.505 |
|
| 1984 |
Gmerek DE, Cowan A. Studies on bombesin-induced grooming in rats. Peptides. 4: 907-13. PMID 6143301 DOI: 10.1016/0196-9781(83)90089-X |
0.471 |
|
| 1984 |
Cowan A. Opioids: past, present and future Trends in Pharmacological Sciences. 5: 3. DOI: 10.1016/0165-6147(84)90345-6 |
0.457 |
|
| 1983 |
Vaught JL, Cowan A, Gmerek DE. A species difference in the slowing effect of intrathecal morphine on gastrointestinal transit European Journal of Pharmacology. 94: 181-184. PMID 6689154 DOI: 10.1016/0014-2999(83)90460-0 |
0.471 |
|
| 1983 |
Gmerek DE, Cowan A, Vaught JL. Intrathecal bombesin in rats: Effects on behaviour and gastrointestinal transit European Journal of Pharmacology. 94: 141-143. PMID 6689153 DOI: 10.1016/0014-2999(83)90451-X |
0.332 |
|
| 1983 |
Porreca F, Cowan A, Raffa RB, Tallarida RJ. Ketazocines and morphine: Effects on gastrointestinal transit after central and peripheral administration Life Sciences. 32: 1785-1790. PMID 6339861 DOI: 10.1016/0024-3205(83)90843-3 |
0.57 |
|
| 1983 |
Tortella FC, Robles LE, Holaday JW, Cowan A. A selective role for δ-receptors in the regulation of opioid-induced changes in seizure threshold Life Sciences. 33: 603-606. PMID 6319916 DOI: 10.1016/0024-3205(83)90575-1 |
0.449 |
|
| 1983 |
Gmerek DE, Cowan A. ACTH-(1-24) and RX 336-M induce excessive grooming in rats through different mechanisms. European Journal of Pharmacology. 88: 339-346. PMID 6305675 DOI: 10.1016/0014-2999(83)90584-8 |
0.446 |
|
| 1983 |
Gmerek DE, Cowan A. An animal model for preclinical screening of systemic antipruritic agents Journal of Pharmacological Methods. 10: 107-112. PMID 6139510 DOI: 10.1016/0160-5402(83)90073-6 |
0.396 |
|
| 1982 |
Tortella FC, Cowan A. EEG, EMG and behavioral evidence for the involvement of endorphin systems in postictal events after electroconvulsive shock in rats Life Sciences. 31: 881-888. PMID 7176817 DOI: 10.1016/0024-3205(82)90544-6 |
0.444 |
|
| 1982 |
Raffa RB, Porreca F, Cowan A, Tallarida RJ. Extraction and measurement of morphine: Correlation of brain level and s.c. dose in drug-naive and morphine-tolerant rats Life Sciences. 31: 2299-2302. PMID 7162345 DOI: 10.1016/0024-3205(82)90142-4 |
0.475 |
|
| 1982 |
Gmerek DE, Cowan A. Classification of opioids on the basis of their ability to antagonize bombesin-induced grooming in rats Life Sciences. 31: 2229-2232. PMID 7162341 DOI: 10.1016/0024-3205(82)90125-4 |
0.563 |
|
| 1982 |
Tortella FC, Cowan A. Studies on opioid peptides as endogenous anticonvulsants Life Sciences. 31: 2225-2228. PMID 7162340 DOI: 10.1016/0024-3205(82)90124-2 |
0.408 |
|
| 1982 |
Tallarida RJ, Robinson MJ, Porreca F, Cowan A. Estimation of the dissociation constant of naloxone in the naive and morphine-tolerant guinea-pig isolated ileum: analysis by the constrained Schild plot. Life Sciences. 31: 1691-4. PMID 7154829 DOI: 10.1016/0024-3205(82)90187-4 |
0.411 |
|
| 1982 |
Gmerek DE, Cowan A. A study of the shaking and grooming induced by RX 336-M in rats. Pharmacology, Biochemistry, and Behavior. 16: 929-32. PMID 7111352 DOI: 10.1016/0091-3057(82)90047-8 |
0.387 |
|
| 1982 |
Porreca F, Cowan A, Tallarida RJ. Differentiation of apomorphine from bromocriptine, piribidel and TRH by chronic administration in rats Psychopharmacology. 76: 70-74. PMID 6805012 DOI: 10.1007/Bf00430759 |
0.423 |
|
| 1982 |
Porreca F, Cowan A, Raffa RB, Tallarida RJ. Estimation in vivo of the receptor constants of morphine in naive and morphine-tolerant rats Life Sciences. 31: 2355-2358. PMID 6298527 DOI: 10.1016/0024-3205(82)90155-2 |
0.542 |
|
| 1982 |
Cowan A, Gmerek DE. In vivo studies with ICI 154,129, a putative delta receptor antagonist. Life Sciences. 31: 2213-2216. PMID 6298518 DOI: 10.1016/0024-3205(82)90121-7 |
0.529 |
|
| 1982 |
Porreca F, Raffa RB, Cowan A, Tallarida RJ. A comparison of the receptor constants of morphine and ethylketocyclazocine for analgesia and inhibition of gastrointestinal transit in the rat Life Sciences. 31: 1955-1961. PMID 6294424 DOI: 10.1016/0024-3205(82)90034-0 |
0.525 |
|
| 1982 |
Raffa RB, Porreca F, Cowan A, Tallarida RJ. Morphine-receptor dissociation constant and the stimulus-effect relation for inhibition of gastrointestinal transit in the rat. European Journal of Pharmacology. 79: 11-6. PMID 6282596 DOI: 10.1016/0014-2999(82)90569-6 |
0.531 |
|
| 1982 |
Cowan A, Tortella FC. A quantitative analysis of the shaking behavior induced in rats by β-endorphin and [D-Ala2, Met5] enkephalinamide Life Sciences. 30: 171-176. PMID 6275233 DOI: 10.1016/0024-3205(82)90649-X |
0.437 |
|
| 1982 |
Sheldon RJ, Cowan A. In vivo and in vitro studies with agents that cause quasi-morphine withdrawal syndromes. Life Sciences. 31: 1699-1702. PMID 6185813 DOI: 10.1016/0024-3205(82)90189-8 |
0.475 |
|
| 1982 |
Porreca F, Cowan A, Raffa RB, Tallarida RJ. Tolerance and cross-tolerance studies with morphine and ethylketocyclazocine Journal of Pharmacy and Pharmacology. 34: 666-667. PMID 6128391 DOI: 10.1111/J.2042-7158.1982.Tb04698.X |
0.413 |
|
| 1982 |
Porreca F, Cowan A, Raffa RB, Tallarida RJ. On the criteria for classifying opiate agonists in rats Journal of Pharmacy and Pharmacology. 34: 525-526. PMID 6126567 DOI: 10.1111/J.2042-7158.1982.Tb04780.X |
0.425 |
|
| 1981 |
Tortella FC, Cowan A, Belenky GL, Holaday JW. Opiate-like electroencephalographic and behavioral effects of electroconvulsive shock in rats. European Journal of Pharmacology. 76: 121-8. PMID 7333352 DOI: 10.1016/0014-2999(81)90493-3 |
0.444 |
|
| 1981 |
Porreca F, Cowan A, Tallarida RJ. Time course of antagonism of morphine antinociception by intracerebroventricularly administered naloxone in the rat European Journal of Pharmacology. 76: 55-59. PMID 7318922 DOI: 10.1016/0014-2999(81)90008-X |
0.479 |
|
| 1981 |
Cowan A, Tortella FC, Adler MW. A comparison of the anticonvulsant effects of two systemically active enkephalin analogues in rats. European Journal of Pharmacology. 71: 117-21. PMID 7238580 DOI: 10.1016/0014-2999(81)90392-7 |
0.521 |
|
| 1981 |
Dettmar PW, Cowan A, Walter DS. A comparison of the neurochemicals effects of buprenorphine with those of morphine and haloperidol in rats European Journal of Pharmacology. 69: 147-153. PMID 7202515 DOI: 10.1016/0014-2999(81)90409-X |
0.492 |
|
| 1981 |
Tortella FC, Cowan A, Adler MW. Comparison of the anticonvulsant effects of opioid peptides and etorphine in rats after icv administration. Life Sciences. 29: 1039-45. PMID 6270480 DOI: 10.1016/0024-3205(81)90464-1 |
0.455 |
|
| 1981 |
Cowan A, Tortella FC, Gmerek DE. Eeg and behavioral studies with zomepirac sodium in rats Pain. 11. DOI: 10.1016/0304-3959(81)90441-3 |
0.308 |
|
| 1980 |
Tortella FC, Cowan A, Adler MW. Pupillary effects of leucine and methionine enkephalin in rats after intraperitoneal administration. Peptides. 1: 237-41. PMID 7232228 DOI: 10.1016/0196-9781(80)90060-1 |
0.529 |
|
| 1980 |
Cowan A. Interactional studies with sodium valproate and naloxone Annals of Neurology. 7: 388-388. PMID 6769384 DOI: 10.1002/Ana.410070420 |
0.305 |
|
| 1980 |
Tortella FC, Cowan A, Adler MW. EEG and behavioral effects of ethylketocyclazocine, morphine and cyclazocine in rats: differential sensitivities towards naloxone. Neuropharmacology. 19: 845-50. PMID 6106909 DOI: 10.1016/0028-3908(80)90081-7 |
0.5 |
|
| 1979 |
Geller EB, Durlofsky L, Cowan A, Harakal C, Adler MW. The effect of pentobarbital on the antinociceptive action of morphine in morphine-tolerant and non-tolerant rats. Life Sciences. 25: 139-45. PMID 573833 DOI: 10.1016/0024-3205(79)90385-0 |
0.511 |
|
| 1979 |
Cowan A, Geller EB, Adler MW. Classification of opioids on the basis of change in seizure threshold in rats. Science (New York, N.Y.). 206: 465-7. PMID 504986 DOI: 10.1126/Science.504986 |
0.546 |
|
| 1979 |
Tallarida RJ, Cowan A, Adler MW. pA2 and receptor differentiation: a statistical analysis of competitive antagonism. Life Sciences. 25: 637-54. PMID 388133 DOI: 10.1016/0024-3205(79)90505-8 |
0.43 |
|
| 1978 |
Dettmar PW, Cowan A, Walter DS. Naloxone antagonizes behavioural effects of d-amphetamine in mice and rats. Neuropharmacology. 17: 1041-1044. PMID 570648 DOI: 10.1016/0028-3908(78)90031-X |
0.468 |
|
| 1978 |
Cowan A, Watson T. Lysergic acid diethylamide antagonizes shaking induced in rats by five chemically different compounds. Psychopharmacology. 57: 43-6. PMID 96468 DOI: 10.1007/Bf00426956 |
0.399 |
|
| 1976 |
Cowan A, Macfarlane IR. Effect of morphine antagonists on drug-induced hypothermia in mice and rats. Psychopharmacologia. 45: 277-82. PMID 1250942 DOI: 10.1007/Bf00421140 |
0.514 |
|
| 1976 |
Cowan A. Use of the mouse jumping test for estimating antagonistic potencies of morphine antagonists. Journal of Pharmacy and Pharmacology. 28: 177-182. PMID 6688 DOI: 10.1111/J.2042-7158.1976.Tb04126.X |
0.471 |
|
| 1975 |
Cowan A, MacFarlane IR. Effect of propranolol on antinociceptive, tolerance- and dependence-producing properties of morphine in rodents and monkeys. European Journal of Pharmacology. 34: 87-94. PMID 11999 DOI: 10.1016/0014-2999(75)90228-9 |
0.517 |
|
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