Year |
Citation |
Score |
2021 |
Lee AS, Tiwari S, Bishop I, Matossian V, Romaneschi N, Miyazaki T, VanderVeen L, Zalevsky J, DeFea K, Cahill CM, Walwyn WM. and Characterization of a Partial Mu Opioid Receptor Agonist, NKTR-181, Supports Future Therapeutic Development. Frontiers in Pain Research (Lausanne, Switzerland). 2: 695962. PMID 35295409 DOI: 10.3389/fpain.2021.695962 |
0.31 |
|
2021 |
Cameron CM, Nieto S, Bosler L, Wong M, Bishop I, Mooney L, Cahill CM. Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine. Advances in Drug and Alcohol Research. 1. PMID 35265942 DOI: 10.3389/adar.2021.10009 |
0.306 |
|
2021 |
Wilson-Poe AR, Wiese B, Kibaly C, Lueptow L, Garcia J, Anand P, Cahill C, Morón JA. Effects of inflammatory pain on CB1 receptor in the midbrain periaqueductal gray. Pain Reports. 6: e897. PMID 33693301 DOI: 10.1097/PR9.0000000000000897 |
0.424 |
|
2021 |
Massaly N, Markovic T, Creed M, Al-Hasani R, Cahill CM, Moron JA. Pain, negative affective states and opioid-based analgesics: Safer pain therapies to dampen addiction. International Review of Neurobiology. 157: 31-68. PMID 33648672 DOI: 10.1016/bs.irn.2020.09.002 |
0.379 |
|
2021 |
Cahill CM, Lueptow L, Kim H, Shusharla R, Bishop A, Evans CJ. Kappa Opioid Signaling at the Crossroads of Chronic Pain and Opioid Addiction. Handbook of Experimental Pharmacology. PMID 33547588 DOI: 10.1007/164_2021_434 |
0.354 |
|
2020 |
Cahill CM, Holdridge SV, Liu SS, Xue L, Magnussen C, Ong E, Grenier P, Sutherland A, Olmstead MC. Delta opioid receptor activation modulates affective pain and modality-specific pain hypersensitivity associated with chronic neuropathic pain. Journal of Neuroscience Research. PMID 32623788 DOI: 10.1002/Jnr.24680 |
0.794 |
|
2019 |
Grenier P, Mailhiot MC, Cahill CM, Olmstead MC. Blockade of dopamine D1 receptors in male rats disrupts morphine reward in pain naïve but not in chronic pain states. Journal of Neuroscience Research. PMID 31721270 DOI: 10.1002/Jnr.24553 |
0.784 |
|
2019 |
Massaly N, Copits BA, Wilson-Poe AR, Hipólito L, Markovic T, Yoon HJ, Liu S, Walicki MC, Bhatti DL, Sirohi S, Klaas A, Walker BM, Neve R, Cahill CM, Shoghi KI, et al. Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System. Neuron. PMID 30878290 DOI: 10.1016/J.Neuron.2019.02.029 |
0.372 |
|
2019 |
Liu SS, Pickens S, Burma NE, Ibarra-Lecue I, Yang H, Xue L, Cook C, Hakimian JK, Severino AL, Lueptow L, Komarek K, Taylor AMW, Olmstead MC, Carroll FI, Bass CE, ... ... Cahill CM, et al. Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30862664 DOI: 10.1523/Jneurosci.0274-19.2019 |
0.35 |
|
2018 |
Grenier P, Wiercigroch D, Olmstead MC, Cahill CM. Dissociation between morphine-induced spinal gliosis and analgesic tolerance by ultra-low-dose α2-adrenergic and cannabinoid CB1-receptor antagonists. Behavioural Pharmacology. PMID 29481424 DOI: 10.1097/Fbp.0000000000000377 |
0.785 |
|
2017 |
Cahill CM, Taylor AM. Neuroinflammation-a co-occurring phenomenon linking chronic pain and opioid dependence. Current Opinion in Behavioral Sciences. 13: 171-177. PMID 28451629 DOI: 10.1016/j.cobeha.2016.12.003 |
0.371 |
|
2017 |
Burma NE, Bonin RP, Leduc-Pessah H, Baimel C, Cairncross ZF, Mousseau M, Shankara JV, Stemkowski PL, Baimoukhametova D, Bains JS, Antle MC, Zamponi GW, Cahill CM, Borgland SL, DeKoninck Y, et al. Blocking microglial pannexin-1 channels alleviates morphine withdrawal in rodents. Nature Medicine. PMID 28134928 DOI: 10.1038/nm.4281 |
0.372 |
|
2016 |
Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G. Molecular Pharmacology of δ-Opioid Receptors. Pharmacological Reviews. 68: 631-700. PMID 27343248 DOI: 10.1124/Pr.114.008979 |
0.374 |
|
2016 |
Taylor AM, Becker S, Schweinhardt P, Cahill C. Mesolimbic dopamine signaling in acute and chronic pain: implications for motivation, analgesia, and addiction. Pain. PMID 26797678 DOI: 10.1097/j.pain.0000000000000494 |
0.315 |
|
2015 |
Trang T, Al-Hasani R, Salvemini D, Salter MW, Gutstein H, Cahill CM. Pain and Poppies: The Good, the Bad, and the Ugly of Opioid Analgesics. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13879-88. PMID 26468188 DOI: 10.1523/Jneurosci.2711-15.2015 |
0.387 |
|
2015 |
Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26202104 DOI: 10.1038/Npp.2015.221 |
0.305 |
|
2015 |
Taylor AM, Castonguay A, Taylor AJ, Murphy NP, Ghogha A, Cook C, Xue L, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. Microglia disrupt mesolimbic reward circuitry in chronic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8442-50. PMID 26041913 DOI: 10.1523/Jneurosci.4036-14.2015 |
0.324 |
|
2015 |
Taylor AM, Roberts KW, Pradhan AA, Akbari HA, Walwyn W, Lutfy K, Carroll FI, Cahill CM, Evans CJ. Anti-nociception mediated by a κ opioid receptor agonist is blocked by a δ receptor agonist. British Journal of Pharmacology. 172: 691-703. PMID 24923251 DOI: 10.1111/Bph.12810 |
0.304 |
|
2015 |
Taylor A, Ghogha A, Cook C, King C, Evans C, Cahill C. (251) Opioids and microglia: a murine-derived microglia stable cell line study The Journal of Pain. 16. DOI: 10.1016/J.Jpain.2015.01.168 |
0.331 |
|
2014 |
Cahill CM, Taylor AM, Cook C, Ong E, Morón JA, Evans CJ. Does the kappa opioid receptor system contribute to pain aversion? Frontiers in Pharmacology. 5: 253. PMID 25452729 DOI: 10.3389/Fphar.2014.00253 |
0.42 |
|
2014 |
Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM. Analgesia, enhancement of spinal morphine antinociception, and inhibition of tolerance by ultra-low dose of the α2A-adrenoceptor selective antagonist BRL44408. European Journal of Pharmacology. 743: 89-97. PMID 25242119 DOI: 10.1016/J.Ejphar.2014.08.040 |
0.788 |
|
2014 |
Taylor AM, Murphy NP, Evans CJ, Cahill CM. Correlation between ventral striatal catecholamine content and nociceptive thresholds in neuropathic mice. The Journal of Pain : Official Journal of the American Pain Society. 15: 878-85. PMID 25052072 DOI: 10.1016/J.Jpain.2014.05.006 |
0.312 |
|
2013 |
Mittal N, Roberts K, Pal K, Bentolila LA, Fultz E, Minasyan A, Cahill C, Pradhan A, Conner D, DeFea K, Evans C, Walwyn W. Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and β-arrestin 1 pathway. Cell Reports. 5: 1010-21. PMID 24239352 DOI: 10.1016/J.Celrep.2013.10.015 |
0.376 |
|
2013 |
Cahill CM, Xue L, Grenier P, Magnussen C, Lecour S, Olmstead MC. Changes in morphine reward in a model of neuropathic pain. Behavioural Pharmacology. 24: 207-13. PMID 23591124 DOI: 10.1097/Fbp.0B013E3283618Ac8 |
0.792 |
|
2013 |
Milne B, Jhamandas K, Sutak M, Grenier P, Cahill CM. Stereo-selective inhibition of spinal morphine tolerance and hyperalgesia by an ultra-low dose of the alpha-2-adrenoceptor antagonist efaroxan. European Journal of Pharmacology. 702: 227-34. PMID 23376415 DOI: 10.1016/J.Ejphar.2013.01.022 |
0.78 |
|
2013 |
Ferrini F, Trang T, Mattioli TA, Laffray S, Del'Guidice T, Lorenzo LE, Castonguay A, Doyon N, Zhang W, Godin AG, Mohr D, Beggs S, Vandal K, Beaulieu JM, Cahill CM, et al. Morphine hyperalgesia gated through microglia-mediated disruption of neuronal Clâ» homeostasis. Nature Neuroscience. 16: 183-92. PMID 23292683 DOI: 10.1038/Nn.3295 |
0.396 |
|
2012 |
Mattioli TA, Sutak M, Milne B, Jhamandas K, Cahill CM. Intrathecal catheterization influences tolerance to chronic morphine in rats. Anesthesia and Analgesia. 114: 690-3. PMID 22190548 DOI: 10.1213/ANE.0b013e31823fad94 |
0.343 |
|
2011 |
Cahill CM, Taylor A. A piece of the puzzle is revealed for delta opioid receptor-mediated analgesia. Pain. 152: 1217-8. PMID 21333447 DOI: 10.1016/j.pain.2011.02.006 |
0.302 |
|
2011 |
Cahill CM, Stroman PW. Mapping of neural activity produced by thermal pain in the healthy human spinal cord and brain stem: a functional magnetic resonance imaging study. Magnetic Resonance Imaging. 29: 342-52. PMID 21247717 DOI: 10.1016/J.Mri.2010.10.007 |
0.306 |
|
2010 |
Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA. Increased abundance of opioid receptor heteromers after chronic morphine administration. Science Signaling. 3: ra54. PMID 20647592 DOI: 10.1126/Scisignal.2000807 |
0.365 |
|
2010 |
Mattioli TA, Milne B, Cahill CM. Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats. Molecular Pain. 6: 22. PMID 20398374 DOI: 10.1186/1744-8069-6-22 |
0.426 |
|
2010 |
Grenier P, Lecour S, Cahill C. 380 THE MOLECULAR AND BEHAVIORAL EFFECTS OF GLIAL MODULATORS PROPENTOFYLLINE AND PJ34 IN NEUROPATHIC PAIN European Journal of Pain Supplements. 4: 108-108. DOI: 10.1016/S1754-3207(10)70385-0 |
0.749 |
|
2008 |
Milne B, Sutak M, Cahill CM, Jhamandas K. Low doses of alpha 2-adrenoceptor antagonists augment spinal morphine analgesia and inhibit development of acute and chronic tolerance. British Journal of Pharmacology. 155: 1264-78. PMID 18806811 DOI: 10.1038/bjp.2008.353 |
0.391 |
|
2007 |
Holdridge SV, Armstrong SA, Taylor AM, Cahill CM. Behavioural and morphological evidence for the involvement of glial cell activation in delta opioid receptor function: implications for the development of opioid tolerance. Molecular Pain. 3: 7. PMID 17352824 DOI: 10.1186/1744-8069-3-7 |
0.391 |
|
2007 |
Holdridge SV, Cahill CM. Spinal administration of a delta opioid receptor agonist attenuates hyperalgesia and allodynia in a rat model of neuropathic pain. European Journal of Pain (London, England). 11: 685-93. PMID 17175187 DOI: 10.1016/j.ejpain.2006.10.008 |
0.467 |
|
2007 |
Gendron L, Esdaile MJ, Mennicken F, Pan H, O'Donnell D, Vincent JP, Devi LA, Cahill CM, Stroh T, Beaudet A. Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin. Neuroscience. 144: 263-74. PMID 17055663 DOI: 10.1016/J.Neuroscience.2006.08.077 |
0.408 |
|
2007 |
Kabli N, Cahill CM. Anti-allodynic effects of peripheral delta opioid receptors in neuropathic pain. Pain. 127: 84-93. PMID 16963185 DOI: 10.1016/j.pain.2006.08.003 |
0.424 |
|
2006 |
Gilron I, Watson CP, Cahill CM, Moulin DE. Neuropathic pain: a practical guide for the clinician. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 175: 265-75. PMID 16880448 DOI: 10.1503/cmaj.060146 |
0.575 |
|
2006 |
Odrcich M, Bailey JM, Cahill CM, Gilron I. Chronobiological characteristics of painful diabetic neuropathy and postherpetic neuralgia: diurnal pain variation and effects of analgesic therapy. Pain. 120: 207-12. PMID 16359793 DOI: 10.1016/j.pain.2005.10.007 |
0.583 |
|
2005 |
Sharif Naeini R, Cahill CM, Ribeiro-da-Silva A, Ménard HA, Henry JL. Remodelling of spinal nociceptive mechanisms in an animal model of monoarthritis. The European Journal of Neuroscience. 22: 2005-15. PMID 16262639 DOI: 10.1111/J.1460-9568.2005.04382.X |
0.308 |
|
2004 |
Morinville A, Cahill CM, Aibak H, Rymar VV, Pradhan A, Hoffert C, Mennicken F, Stroh T, Sadikot AF, O'Donnell D, Clarke PB, Collier B, Henry JL, Vincent JP, Beaudet A. Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5549-59. PMID 15201327 DOI: 10.1523/Jneurosci.2719-03.2004 |
0.345 |
|
2004 |
Morinville A, Cahill CM, Kieffer B, Collier B, Beaudet A. Mu-opioid receptor knockout prevents changes in delta-opioid receptor trafficking induced by chronic inflammatory pain. Pain. 109: 266-73. PMID 15157687 DOI: 10.1016/J.Pain.2004.01.011 |
0.352 |
|
2004 |
Kabli N, Holdridge S, Cahill C. Opioid action The Journal of Pain. 5: S28. DOI: 10.1016/j.jpain.2004.02.078 |
0.377 |
|
2003 |
Cahill CM, Dray A, Coderre TJ. Intrathecal nerve growth factor restores opioid effectiveness in an animal model of neuropathic pain. Neuropharmacology. 45: 543-52. PMID 12907315 DOI: 10.1016/S0028-3908(03)00192-8 |
0.666 |
|
2003 |
Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A. Regulation of delta-opioid receptor trafficking via mu-opioid receptor stimulation: evidence from mu-opioid receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4888-98. PMID 12832511 |
0.373 |
|
2003 |
Cahill CM, Morinville A, Hoffert C, O'Donnell D, Beaudet A. Up-regulation and trafficking of delta opioid receptor in a model of chronic inflammation: implications for pain control. Pain. 101: 199-208. PMID 12507715 DOI: 10.1016/S0304-3959(02)00333-0 |
0.409 |
|
2003 |
Cahill CM, Dray A, Coderre TJ. Enhanced thermal antinociceptive potency and anti-allodynic effects of morphine following spinal administration of endotoxin. Brain Research. 960: 209-18. PMID 12505674 DOI: 10.1016/S0006-8993(02)03885-4 |
0.606 |
|
2003 |
Morinville A, Cahill CM, Esdaile MJ, Aibak H, Collier B, Kieffer BL, Beaudet A. Regulation of δ-Opioid Receptor Trafficking via μ-Opioid Receptor Stimulation: Evidence from μ-Opioid Receptor Knock-Out Mice The Journal of Neuroscience. 23: 4888-4898. DOI: 10.1523/Jneurosci.23-12-04888.2003 |
0.373 |
|
2002 |
Cahill CM, Coderre TJ. Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist. Pain. 95: 277-85. PMID 11839427 DOI: 10.1016/S0304-3959(01)00410-9 |
0.624 |
|
2001 |
Cahill CM, Morinville A, Lee MC, Vincent JP, Collier B, Beaudet A. Prolonged morphine treatment targets delta opioid receptors to neuronal plasma membranes and enhances delta-mediated antinociception. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7598-607. PMID 11567050 |
0.345 |
|
2000 |
Lefebvre C, Fisher K, Cahill CM, Coderre TJ. Evidence that DHPG-induced nociception depends on glutamate release from primary afferent C-fibres. Neuroreport. 11: 1631-5. PMID 10852214 DOI: 10.1097/00001756-200006050-00007 |
0.709 |
|
2000 |
Cahill CM, Coderre TJ. Spinal NGF Restores Opioid Sensitivity in Neuropathic Rats: Possible Role of NGF as a Regulator of CCK-Induced Anti-Opioid Effects Pain Research and Management. 5: 49-57. DOI: 10.1155/2000/347212 |
0.644 |
|
2000 |
Cahill CM. Spinal NGF restores opioid sensitivity in neuropathic rats: Possible role of NGF as a regulator of CCK-induced anti-opioid effects Pain Research and Management. 5: 49-57. |
0.34 |
|
1998 |
Cahill CM, Dray A, Coderre TJ. Priming enhances endotoxin-induced thermal hyperalgesia and mechanical allodynia in rats. Brain Research. 808: 13-22. PMID 9795108 DOI: 10.1016/S0006-8993(98)00786-0 |
0.57 |
|
1998 |
Fisher K, Fundytus ME, Cahill CM, Coderre TJ. Intrathecal administration of the mGluR compound, (S)-4CPG, attenuates hyperalgesia and allodynia associated with sciatic nerve constriction injury in rats. Pain. 77: 59-66. PMID 9755019 DOI: 10.1016/S0304-3959(98)00082-7 |
0.749 |
|
1997 |
Cahill CM, White TD, Sawynok J. Substance P releases and augments the morphine-evoked release of adenosine from spinal cord. Brain Research. 760: 294-7. PMID 9237551 DOI: 10.1016/S0006-8993(97)00473-3 |
0.573 |
|
1996 |
Cahill CM, White TD, Sawynok J. Synergy between mu/delta-opioid receptors mediates adenosine release from spinal cord synaptosomes. European Journal of Pharmacology. 298: 45-9. PMID 8867918 DOI: 10.1016/0014-2999(95)00775-X |
0.627 |
|
1995 |
Cahill CM, White TD, Sawynok J. Spinal opioid receptors and adenosine release: neurochemical and behavioral characterization of opioid subtypes. The Journal of Pharmacology and Experimental Therapeutics. 275: 84-93. PMID 7562600 |
0.644 |
|
1993 |
Sawynok J, Downie JW, Reid AR, Cahill CM, White TD. ATP release from dorsal spinal cord synaptosomes: characterization and neuronal origin. Brain Research. 610: 32-8. PMID 8518929 DOI: 10.1016/0006-8993(93)91213-C |
0.552 |
|
1993 |
Cahill CM, White TD, Sawynok J. Influence of calcium on the release of endogenous adenosine from spinal cord synaptosomes. Life Sciences. 53: 487-96. PMID 8341135 DOI: 10.1016/0024-3205(93)90700-D |
0.56 |
|
1993 |
Cahill CM, White TD, Sawynok J. Morphine activates omega-conotoxin-sensitive Ca2+ channels to release adenosine from spinal cord synaptosomes. Journal of Neurochemistry. 60: 894-901. PMID 7679729 DOI: 10.1111/j.1471-4159.1993.tb03234.x |
0.587 |
|
1993 |
Cahill CM, White TD, Sawynok J. Involvement of calcium channels in depolarization-evoked release of adenosine from spinal cord synaptosomes. Journal of Neurochemistry. 60: 886-93. PMID 7679728 DOI: 10.1111/J.1471-4159.1993.Tb03233.X |
0.531 |
|
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