| Year |
Citation |
Score |
| 2023 |
Ribeiro FC, Cozachenco D, Heimfarth L, Fortuna JTS, de Freitas GB, de Sousa JM, Alves-Leon SV, Leite REP, Suemoto CK, Grinberg LT, De Felice FG, Lourenco MV, Ferreira ST. Synaptic proteasome is inhibited in Alzheimer's disease models and associates with memory impairment in mice. Communications Biology. 6: 1127. PMID 37935829 DOI: 10.1038/s42003-023-05511-9 |
0.457 |
|
| 2023 |
Lima-Filho RAS, Benedet AL, De Bastiani MA, Povala G, Cozachenco D, Ferreira ST, De Felice FG, Rosa-Neto P, Zimmer ER, Lourenco MV. Association of the fibronectin type III domain-containing protein 5 rs1746661 single nucleotide polymorphism with reduced brain glucose metabolism in elderly humans. Brain Communications. 5: fcad216. PMID 37601408 DOI: 10.1093/braincomms/fcad216 |
0.395 |
|
| 2023 |
Bodart-Santos V, Pinheiro LS, da Silva-Junior AJ, Froza RL, Ahrens R, Gonçalves RA, Andrade MM, Chen Y, Alcantara CL, Grinberg LT, Leite REP, Ferreira ST, Fraser PE, De Felice FG. Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37204850 DOI: 10.1002/alz.13134 |
0.543 |
|
| 2023 |
Lima-Filho R, Fortuna JS, Cozachenco D, Isaac AR, Lyra E Silva N, Saldanha A, Santos LE, Ferreira ST, Lourenco MV, De Felice FG. Brain FNDC5/irisin expression in patients and mouse models of major depression. Eneuro. PMID 36697257 DOI: 10.1523/ENEURO.0256-22.2023 |
0.73 |
|
| 2022 |
Gonçalves RA, Sudo FK, Lourenco MV, Drummond C, Assunção N, Vanderborght B, Ferreira DDP, Ribeiro FC, Pamplona FA, Tovar-Moll F, Mattos P, Ferreira ST, De Felice FG. Cerebrospinal fluid irisin and lipoxin A4 are reduced in elderly Brazilian individuals with depression: Insight into shared mechanisms between depression and dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36465055 DOI: 10.1002/alz.12893 |
0.701 |
|
| 2022 |
Selles MC, Fortuna JTS, Cercato MC, Santos LE, Domett L, Bitencourt ALB, Carraro MF, Souza AS, Janickova H, Azevedo CV, Campos HC, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, ... ... De Felice FG, et al. AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36369741 DOI: 10.1016/j.ymthe.2022.11.002 |
0.473 |
|
| 2022 |
Lourenco MV, de Freitas GB, Raony Í, Ferreira ST, De Felice FG. Irisin stimulates protective signaling pathways in rat hippocampal neurons. Frontiers in Cellular Neuroscience. 16: 953991. PMID 36187295 DOI: 10.3389/fncel.2022.953991 |
0.794 |
|
| 2022 |
Rody T, De Amorim JA, De Felice FG. The emerging neuroprotective roles of exerkines in Alzheimer's disease. Frontiers in Aging Neuroscience. 14: 965190. PMID 36118704 DOI: 10.3389/fnagi.2022.965190 |
0.442 |
|
| 2022 |
Robertson EL, Boehnke SE, Lyra E Silva NM, Armitage-Brown B, Winterborn A, Cook DJ, De Felice FG, Munoz DP. Characterization of cerebrospinal fluid biomarkers associated with neurodegenerative diseases in healthy cynomolgus and rhesus macaque monkeys. Alzheimer's & Dementia (New York, N. Y.). 8: e12289. PMID 35415210 DOI: 10.1002/trc2.12289 |
0.3 |
|
| 2022 |
Lyra E Silva NM, Barros-Aragão FGQ, De Felice FG, Ferreira ST. Inflammation at the crossroads of COVID-19, cognitive deficits and depression. Neuropharmacology. 209: 109023. PMID 35257690 DOI: 10.1016/j.neuropharm.2022.109023 |
0.313 |
|
| 2022 |
De Felice FG, Gonçalves RA, Ferreira ST. Impaired insulin signalling and allostatic load in Alzheimer disease. Nature Reviews. Neuroscience. 23: 215-230. PMID 35228741 DOI: 10.1038/s41583-022-00558-9 |
0.443 |
|
| 2021 |
Gonçalves RA, De Felice FG. The crosstalk between brain and periphery: Implications for brain health and disease. Neuropharmacology. 108728. PMID 34331960 DOI: 10.1016/j.neuropharm.2021.108728 |
0.318 |
|
| 2021 |
Lourenco MV, Ribeiro FC, Santos LE, Beckman D, Melo HM, Sudo FK, Drummond C, Assunção N, Vanderborght B, Tovar-Moll F, De Felice FG, Mattos P, Ferreira ST. Cerebrospinal Fluid Neurotransmitters, Cytokines, and Chemokines in Alzheimer's and Lewy Body Diseases. Journal of Alzheimer's Disease : Jad. PMID 34151795 DOI: 10.3233/JAD-210147 |
0.776 |
|
| 2021 |
Lyra E Silva NM, Gonçalves RA, Pascoal TA, Lima-Filho RAS, Resende EPF, Vieira ELM, Teixeira AL, de Souza LC, Peny JA, Fortuna JTS, Furigo IC, Hashiguchi D, Miya-Coreixas VS, Clarke JR, Abisambra JF, ... ... De Felice FG, et al. Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease. Translational Psychiatry. 11: 251. PMID 33911072 DOI: 10.1038/s41398-021-01349-z |
0.479 |
|
| 2021 |
Wijesekara N, Gonçalves RA, Ahrens R, Ha K, De Felice FG, Fraser PE. Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice. The Journal of Pathology. PMID 33797777 DOI: 10.1002/path.5674 |
0.414 |
|
| 2021 |
Batista AF, Rody T, Forny-Germano L, Cerdeiro S, Bellio M, Ferreira ST, Munoz DP, De Felice FG. Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers. Journal of Neuroinflammation. 18: 54. PMID 33612100 DOI: 10.1186/s12974-021-02099-x |
0.78 |
|
| 2021 |
Oliveira MM, Lourenco MV, Longo F, Kasica NP, Yang W, Ureta G, Ferreira DDP, Mendonça PHJ, Bernales S, Ma T, De Felice FG, Klann E, Ferreira ST. Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer's disease. Science Signaling. 14. PMID 33531382 DOI: 10.1126/scisignal.abc5429 |
0.801 |
|
| 2020 |
Lourenco MV, Ribeiro FC, Sudo FK, Drummond C, Assunção N, Vanderborght B, Tovar-Moll F, Mattos P, De Felice FG, Ferreira ST. Cerebrospinal fluid irisin correlates with amyloid-β, BDNF, and cognition in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12034. PMID 32582833 DOI: 10.1002/Dad2.12034 |
0.804 |
|
| 2020 |
de Freitas GB, Lourenco MV, De Felice FG. Protective actions of exercise-related FNDC5/Irisin in memory and Alzheimer's disease. Journal of Neurochemistry. PMID 32396989 DOI: 10.1111/jnc.15039 |
0.782 |
|
| 2020 |
Mejido DCP, Andrade J, Vieira MNN, Ferreira ST, De Felice FG. Insulin and leptin as potential cognitive enhancers in metabolic disorders and Alzheimer's disease. Neuropharmacology. 108115. PMID 32344008 DOI: 10.1016/J.Neuropharm.2020.108115 |
0.376 |
|
| 2020 |
Gonçalves RA, Wijesekara N, Fraser PE, De Felice FG. Behavioral Abnormalities in Knockout and Humanized Tau Mice. Frontiers in Endocrinology. 11: 124. PMID 32226410 DOI: 10.3389/Fendo.2020.00124 |
0.414 |
|
| 2020 |
Melo HM, Seixas da Silva GDS, Sant'Ana MR, Teixeira CVL, Clarke JR, Miya Coreixas VS, de Melo BC, Fortuna JTS, Forny-Germano L, Ledo JH, Oliveira MS, Figueiredo CP, Pardossi-Piquard R, Checler F, Delgado-García JM, ... ... De Felice FG, et al. Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α. Cell Reports. PMID 32075735 DOI: 10.1016/J.Celrep.2020.01.072 |
0.311 |
|
| 2020 |
Selles MC, Fortuna J, Cercato MC, Santos LE, Domett L, Bitencourt AL, Souza AS, Janickova H, Souza JM, Alves‐Leon S, Prado V, Prado MA, Epstein A, Salvetti A, Sebollela A, ... ... De Felice FG, et al. Neuronal expression of a single‐chain variable fragment antibody against Aβ oligomers protects synapses and rescues memory in Alzheimer models Alzheimer's & Dementia. 16. DOI: 10.1002/alz.041530 |
0.379 |
|
| 2019 |
Bodart-Santos V, de Carvalho LRP, de Godoy MA, Batista AF, Saraiva LM, Lima LG, Abreu CA, De Felice FG, Galina A, Mendez-Otero R, Ferreira ST. Extracellular vesicles derived from human Wharton's jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. Stem Cell Research & Therapy. 10: 332. PMID 31747944 DOI: 10.1186/S13287-019-1432-5 |
0.751 |
|
| 2019 |
Figueiredo CP, Barros-Aragão FGQ, Neris RLS, Frost PS, Soares C, Souza INO, Zeidler JD, Zamberlan DC, de Sousa VL, Souza AS, Guimarães ALA, Bellio M, Marcondes de Souza J, Alves-Leon SV, Neves GA, ... ... De Felice FG, et al. Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice. Nature Communications. 10: 3890. PMID 31488835 DOI: 10.1038/S41467-019-11866-7 |
0.316 |
|
| 2019 |
Frost PS, Barros-Aragão F, da Silva RT, Venancio A, Matias I, Lyra E Silva NM, Kincheski GC, Pimentel-Coelho PM, De Felice FG, Gomes FCA, Ferreira ST, Figueiredo CP, Clarke JR. Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice. Cell Death & Disease. 10: 323. PMID 30975983 DOI: 10.1038/S41419-019-1529-X |
0.326 |
|
| 2019 |
Lyra E Silva NM, Gonçalves RA, Boehnke SE, Forny-Germano L, Munoz DP, De Felice FG. Understanding the link between insulin resistance and Alzheimer's disease: Insights from animal models. Experimental Neurology. PMID 30930096 DOI: 10.1016/j.expneurol.2019.03.016 |
0.545 |
|
| 2019 |
Gonçalves RA, Wijesekara N, Fraser PE, De Felice FG. The Link Between Tau and Insulin Signaling: Implications for Alzheimer's Disease and Other Tauopathies. Frontiers in Cellular Neuroscience. 13: 17. PMID 30804755 DOI: 10.3389/Fncel.2019.00017 |
0.393 |
|
| 2019 |
Lourenco MV, Frozza RL, de Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, Gonçalves RA, Clarke JR, Beckman D, Staniszewski A, Berman H, Guerra LA, Forny-Germano L, Meier S, Wilcock DM, ... ... De Felice FG, et al. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models. Nature Medicine. 25: 165-175. PMID 30617325 DOI: 10.1038/S41591-018-0275-4 |
0.795 |
|
| 2018 |
Ferreira LSS, Fernandes CS, Vieira MNN, De Felice FG. Insulin Resistance in Alzheimer's Disease. Frontiers in Neuroscience. 12: 830. PMID 30542257 DOI: 10.3389/Fnins.2018.00830 |
0.404 |
|
| 2018 |
Batista AF, Bodart-Santos V, De Felice FG, Ferreira ST. Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer's and Parkinson's Diseases. Cns Drugs. PMID 30511349 DOI: 10.1007/S40263-018-0593-6 |
0.777 |
|
| 2018 |
Mendes ND, Fernandes A, Almeida GM, Santos LE, Selles MC, Lyra-Silva N, Machado CM, Horta-Júnior JAC, Louzada PR, De Felice FG, Alvez-Leon S, Marcondes J, Assirati JA, Matias CM, Klein WL, et al. Free-floating adult human brain-derived slice cultures as a model to study the neuronal impact of Alzheimer's disease-associated Aβ oligomers: Alzheimer-like toxicity in cultured human brain slices. Journal of Neuroscience Methods. PMID 29859877 DOI: 10.1016/J.Jneumeth.2018.05.021 |
0.309 |
|
| 2018 |
Hölscher C, De Felice FG, Greig N, Ferreira ST. Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones? Neuropharmacology. PMID 29782874 DOI: 10.1016/J.Neuropharm.2018.05.021 |
0.357 |
|
| 2018 |
Clarke JR, Ribeiro FC, Frozza RL, De Felice FG, Lourenco MV. Metabolic Dysfunction in Alzheimer's Disease: From Basic Neurobiology to Clinical Approaches. Journal of Alzheimer's Disease : Jad. PMID 29562518 DOI: 10.3233/JAD-179911 |
0.787 |
|
| 2018 |
Frozza RL, Lourenco MV, De Felice FG. Challenges for Alzheimer's Disease Therapy: Insights from Novel Mechanisms Beyond Memory Defects. Frontiers in Neuroscience. 12: 37. PMID 29467605 DOI: 10.3389/fnins.2018.00037 |
0.807 |
|
| 2018 |
Furigo IC, Melo HM, Lyra E Silva NM, Ramos-Lobo AM, Teixeira PDS, Buonfiglio DC, Wasinski F, Lima ER, Higuti E, Peroni CN, Bartolini P, Soares CRJ, Metzger M, de Felice FG, Donato J. Brain STAT5 signaling modulates learning and memory formation. Brain Structure & Function. PMID 29460051 DOI: 10.1007/s00429-018-1627-z |
0.326 |
|
| 2018 |
Batista AF, Forny-Germano L, Clarke JR, Lyra E Silva NM, Brito-Moreira J, Boehnke SE, Winterborn A, Coe BC, Lablans A, Vital JF, Marques SA, Martinez AMB, Gralle M, Holscher C, Klein WL, ... ... De Felice FG, et al. The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease. The Journal of Pathology. PMID 29435980 DOI: 10.1002/Path.5056 |
0.821 |
|
| 2017 |
Godoy MA, Saraiva LM, Carvalho LRP, Vasconcelos-Dos-Santos A, Beiral HJV, Ramos AB, Silva LRP, Leal RB, Monteiro VHS, Braga CV, Araujo-Silva CA, Sinis LC, Santos VB, Brunswick THK, Alcantara CL, ... ... De Felice FG, et al. Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. The Journal of Biological Chemistry. PMID 29284679 DOI: 10.1074/Jbc.M117.807180 |
0.386 |
|
| 2017 |
Wijesekara N, Gonçalves da Silva RA, De Felice FG, Fraser PE. Impaired peripheral glucose homeostasis and Alzheimer's disease. Neuropharmacology. PMID 29169962 DOI: 10.1016/J.Neuropharm.2017.11.027 |
0.555 |
|
| 2017 |
Vieira MNN, Lima-Filho RAS, De Felice FG. Connecting Alzheimer's disease to diabetes: Underlying mechanisms and potential therapeutic targets. Neuropharmacology. PMID 29129775 DOI: 10.1016/j.neuropharm.2017.11.014 |
0.478 |
|
| 2017 |
Pitt J, Wilcox KC, Tortelli V, Diniz LP, Oliveira MS, Dobbins C, Yu XW, Nandamuri S, Gomes FCA, DiNunno N, Viola KL, De Felice FG, Ferreira ST, Klein WL. Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers. Molecular Biology of the Cell. 28: 2623-2636. PMID 28963439 DOI: 10.1091/Mbc.E17-06-0416 |
0.352 |
|
| 2017 |
Pitt J, Wilcox KC, Tortelli V, Diniz LP, Oliveira MS, Dobbins C, Yu XW, Nandamuri S, Gomes FCA, DiNunno N, Viola KL, De Felice FG, Ferreira ST, Klein WL. Neuroprotective astrocyte-derived insulin/IGF-1 stimulate endocytic processing and extracellular release of neuron-bound Aβ oligomers. Molecular Biology of the Cell. PMID 28794261 DOI: 10.1091/mbc.E17-06-0416 |
0.373 |
|
| 2017 |
Diniz LP, Tortelli V, Matias I, Morgado J, Paula Bérgamo Araujo A, Melo HM, Seixas da Silva GS, Alves-Leon SV, de Souza JM, Ferreira ST, De Felice FG, Alcantara Gomes FC. Astrocyte transforming growth factor beta 1 protects synapses against Aβ oligomers in Alzheimer's disease model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28607171 DOI: 10.1523/Jneurosci.3351-16.2017 |
0.378 |
|
| 2017 |
Seixas da Silva GS, Melo HM, Lourenco MV, Lyra E Silva NM, de Carvalho MB, Alves-Leon S, de Souza JM, Klein WL, da-Silva WS, Ferreira ST, De Felice FG. Amyloid-β Oligomers Transiently Inhibit AMP-activated kinase and Cause Metabolic Defects in Hippocampal Neurons. The Journal of Biological Chemistry. PMID 28302722 DOI: 10.1074/Jbc.M116.753525 |
0.76 |
|
| 2017 |
Brito-Moreira J, Lourenco MV, Oliveira MM, Vital JF, Ribeiro FC, Ledo JH, Diniz LP, Magdesian MH, Melo HM, Aragão FB, de Souza JM, Alves-Leon SV, Gomes FC, Clarke JR, Figueiredo CP, ... De Felice FG, et al. Interaction of Aβ Oligomers with Neurexin 2α and Neuroligin 1 Mediates Synapse Damage and Memory Loss in Mice. The Journal of Biological Chemistry. PMID 28283575 DOI: 10.1074/Jbc.M116.761189 |
0.795 |
|
| 2017 |
Vieira MN, Lyra E Silva NM, Ferreira ST, De Felice FG. Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer's Therapy? Frontiers in Aging Neuroscience. 9: 7. PMID 28197094 DOI: 10.3389/Fnagi.2017.00007 |
0.536 |
|
| 2016 |
Neves FS, Marques PT, Barros-Aragão F, Nunes JB, Venancio AM, Cozachenco D, Frozza RL, Passos GF, Costa R, de Oliveira J, Engel DF, De Bem AF, Benjamim CF, De Felice FG, Ferreira ST, et al. Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice. Molecular Neurobiology. PMID 27966074 DOI: 10.1007/S12035-016-0307-3 |
0.336 |
|
| 2016 |
Ledo JH, Azevedo EP, Beckman D, Ribeiro FC, Santos LE, Razolli DS, Kincheski GC, Melo HM, Bellio M, Teixeira AL, Velloso LA, Foguel D, De Felice FG, Ferreira ST. Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 12106-12116. PMID 27903721 DOI: 10.1523/Jneurosci.1269-16.2016 |
0.407 |
|
| 2016 |
De Felice FG, Munoz DP. Opportunities and challenges in developing relevant animal models for Alzheimer's disease. Ageing Research Reviews. PMID 26829469 DOI: 10.1016/j.arr.2016.01.006 |
0.384 |
|
| 2015 |
Ferreira ST, Lourenco MV, Oliveira MM, De Felice FG. Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer's disease. Frontiers in Cellular Neuroscience. 9: 191. PMID 26074767 DOI: 10.3389/Fncel.2015.00191 |
0.814 |
|
| 2015 |
De Felice FG, Lourenco MV. Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer's disease. Frontiers in Aging Neuroscience. 7: 94. PMID 26042036 DOI: 10.3389/fnagi.2015.00094 |
0.816 |
|
| 2015 |
Lourenco MV, Ferreira ST, De Felice FG. Neuronal stress signaling and eIF2α phosphorylation as molecular links between Alzheimer's disease and diabetes. Progress in Neurobiology. 129: 37-57. PMID 25857551 DOI: 10.1016/J.Pneurobio.2015.03.003 |
0.802 |
|
| 2015 |
Clarke JR, Lyra E Silva NM, Figueiredo CP, Frozza RL, Ledo JH, Beckman D, Katashima CK, Razolli D, Carvalho BM, Frazão R, Silveira MA, Ribeiro FC, Bomfim TR, Neves FS, Klein WL, ... ... De Felice FG, et al. Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. Embo Molecular Medicine. 7: 190-210. PMID 25617315 DOI: 10.15252/Emmm.201404183 |
0.475 |
|
| 2014 |
Forny-Germano L, Lyra e Silva NM, Batista AF, Brito-Moreira J, Gralle M, Boehnke SE, Coe BC, Lablans A, Marques SA, Martinez AM, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 13629-43. PMID 25297091 DOI: 10.1523/Jneurosci.1353-14.2014 |
0.828 |
|
| 2014 |
De Felice FG, Ferreira ST. Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to Alzheimer disease. Diabetes. 63: 2262-72. PMID 24931033 DOI: 10.2337/Db13-1954 |
0.511 |
|
| 2014 |
Ferreira ST, Clarke JR, Bomfim TR, De Felice FG. Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S76-83. PMID 24529528 DOI: 10.1016/J.Jalz.2013.12.010 |
0.514 |
|
| 2014 |
De Felice FG, Lourenco MV, Ferreira ST. How does brain insulin resistance develop in Alzheimer's disease? Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S26-32. PMID 24529521 DOI: 10.1016/J.Jalz.2013.12.004 |
0.794 |
|
| 2013 |
Lourenco MV, Clarke JR, Frozza RL, Bomfim TR, Forny-Germano L, Batista AF, Sathler LB, Brito-Moreira J, Amaral OB, Silva CA, Freitas-Correa L, EspÃrito-Santo S, Campello-Costa P, Houzel JC, Klein WL, ... ... De Felice FG, et al. TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's β-amyloid oligomers in mice and monkeys. Cell Metabolism. 18: 831-43. PMID 24315369 DOI: 10.1016/J.Cmet.2013.11.002 |
0.829 |
|
| 2013 |
Figueiredo CP, Clarke JR, Ledo JH, Ribeiro FC, Costa CV, Melo HM, Mota-Sales AP, Saraiva LM, Klein WL, Sebollela A, De Felice FG, Ferreira ST. Memantine rescues transient cognitive impairment caused by high-molecular-weight aβ oligomers but not the persistent impairment induced by low-molecular-weight oligomers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9626-34. PMID 23739959 DOI: 10.1523/Jneurosci.0482-13.2013 |
0.437 |
|
| 2013 |
Freiherr J, Hallschmid M, Frey WH, Brünner YF, Chapman CD, Hölscher C, Craft S, De Felice FG, Benedict C. Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence. Cns Drugs. 27: 505-14. PMID 23719722 DOI: 10.1007/S40263-013-0076-8 |
0.39 |
|
| 2013 |
De Felice FG. Alzheimer's disease and insulin resistance: translating basic science into clinical applications. The Journal of Clinical Investigation. 123: 531-9. PMID 23485579 DOI: 10.1172/JCI64595 |
0.514 |
|
| 2013 |
Ledo JH, Azevedo EP, Clarke JR, Ribeiro FC, Figueiredo CP, Foguel D, De Felice FG, Ferreira ST. Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice. Molecular Psychiatry. 18: 1053-4. PMID 23183490 DOI: 10.1038/Mp.2012.168 |
0.4 |
|
| 2012 |
Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, ... ... De Felice FG, et al. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers. The Journal of Clinical Investigation. 122: 1339-53. PMID 22476196 DOI: 10.1172/Jci57256 |
0.555 |
|
| 2012 |
Sebollela A, Freitas-Correa L, Oliveira FF, Paula-Lima AC, Saraiva LM, Martins SM, Mota LD, Torres C, Alves-Leon S, de Souza JM, Carraro DM, Brentani H, De Felice FG, Ferreira ST. Amyloid-β oligomers induce differential gene expression in adult human brain slices. The Journal of Biological Chemistry. 287: 7436-45. PMID 22235132 DOI: 10.1074/Jbc.M111.298471 |
0.442 |
|
| 2010 |
Saraiva LM, Seixas da Silva GS, Galina A, da-Silva WS, Klein WL, Ferreira ST, De Felice FG. Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria. Plos One. 5: e15230. PMID 21179577 DOI: 10.1371/Journal.Pone.0015230 |
0.33 |
|
| 2010 |
Decker H, Jürgensen S, Adrover MF, Brito-Moreira J, Bomfim TR, Klein WL, Epstein AL, De Felice FG, Jerusalinsky D, Ferreira ST. N-methyl-D-aspartate receptors are required for synaptic targeting of Alzheimer's toxic amyloid-β peptide oligomers. Journal of Neurochemistry. 115: 1520-9. PMID 20950339 DOI: 10.1111/J.1471-4159.2010.07058.X |
0.357 |
|
| 2009 |
Pitt J, Roth W, Lacor P, Smith AB, Blankenship M, Velasco P, De Felice F, Breslin P, Klein WL. Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicology and Applied Pharmacology. 240: 189-97. PMID 19631677 DOI: 10.1016/J.Taap.2009.07.018 |
0.369 |
|
| 2009 |
De Felice FG, Vieira MN, Bomfim TR, Decker H, Velasco PT, Lambert MP, Viola KL, Zhao WQ, Ferreira ST, Klein WL. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. Proceedings of the National Academy of Sciences of the United States of America. 106: 1971-6. PMID 19188609 DOI: 10.1073/Pnas.0809158106 |
0.36 |
|
| 2008 |
Zhao WQ, De Felice FG, Fernandez S, Chen H, Lambert MP, Quon MJ, Krafft GA, Klein WL. Amyloid beta oligomers induce impairment of neuronal insulin receptors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 246-60. PMID 17720802 DOI: 10.1096/Fj.06-7703Com |
0.426 |
|
| 2008 |
De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers. Neurobiology of Aging. 29: 1334-47. PMID 17403556 DOI: 10.1016/J.Neurobiolaging.2007.02.029 |
0.473 |
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| 2007 |
Vieira MN, Forny-Germano L, Saraiva LM, Sebollela A, Martinez AM, Houzel JC, De Felice FG, Ferreira ST. Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration. Journal of Neurochemistry. 103: 736-48. PMID 17727639 DOI: 10.1111/J.1471-4159.2007.04809.X |
0.373 |
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| 2007 |
De Felice FG, Wasilewska-Sampaio AP, Barbosa AC, Gomes FC, Klein WL, Ferreira ST. Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer's disease. Current Alzheimer Research. 4: 263-71. PMID 17627483 DOI: 10.2174/156720507781077287 |
0.494 |
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| 2007 |
Ferreira ST, Vieira MN, De Felice FG. Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases. Iubmb Life. 59: 332-45. PMID 17505973 DOI: 10.1080/15216540701283882 |
0.342 |
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| 2007 |
De Felice FG, Velasco PT, Lambert MP, Viola K, Fernandez SJ, Ferreira ST, Klein WL. Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. The Journal of Biological Chemistry. 282: 11590-601. PMID 17308309 DOI: 10.1074/Jbc.M607483200 |
0.312 |
|
| 2007 |
Lambert MP, Velasco PT, Chang L, Viola KL, Fernandez S, Lacor PN, Khuon D, Gong Y, Bigio EH, Shaw P, De Felice FG, Krafft GA, Klein WL. Monoclonal antibodies that target pathological assemblies of Abeta. Journal of Neurochemistry. 100: 23-35. PMID 17116235 DOI: 10.1111/J.1471-4159.2006.04157.X |
0.376 |
|
| 2005 |
Paula-Lima AC, De Felice FG, Brito-Moreira J, Ferreira ST. Activation of GABA(A) receptors by taurine and muscimol blocks the neurotoxicity of beta-amyloid in rat hippocampal and cortical neurons. Neuropharmacology. 49: 1140-8. PMID 16150468 DOI: 10.1016/J.Neuropharm.2005.06.015 |
0.327 |
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| 2004 |
De Felice FG, Vieira MN, Saraiva LM, Figueroa-Villar JD, Garcia-Abreu J, Liu R, Chang L, Klein WL, Ferreira ST. Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1366-72. PMID 15333579 DOI: 10.1096/Fj.04-1764Com |
0.349 |
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| 2002 |
De Felice FG, Ferreira ST. Beta-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease. Cellular and Molecular Neurobiology. 22: 545-63. PMID 12585679 DOI: 10.1023/A:1021832302524 |
0.46 |
|
| 2001 |
De Felice FG, Houzel JC, Garcia-Abreu J, Louzada PR, Afonso RC, Meirelles MN, Lent R, Neto VM, Ferreira ST. Inhibition of Alzheimer's disease beta-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: implications for Alzheimer's therapy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1297-9. PMID 11344119 DOI: 10.1096/Fj.00-0676Fje |
0.348 |
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