| Year |
Citation |
Score |
| 2023 |
Coulombe P, Cole G, Fentiman A, Parker JDK, Yung E, Bilenky M, Degefie L, Lac P, Ling MYM, Tam D, Humphries RK, Karsan A. Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression. Nature Communications. 14: 4537. PMID 37500618 DOI: 10.1038/s41467-023-40283-0 |
0.307 |
|
| 2020 |
Calvente L, Tremblay-LeMay R, Xu W, Chan FC, Hong M, Zhang T, Yhim HY, Kuruvilla J, Crump M, Kukreti V, Prica A, Regier D, Marra MA, Karsan A, Steidl C, et al. Validation of the RHL30 digital gene expression assay as a prognostic biomarker for relapsed Hodgkin lymphoma. British Journal of Haematology. PMID 32510594 DOI: 10.1111/Bjh.16777 |
0.306 |
|
| 2020 |
Martinez-Høyer S, Deng Y, Parker J, Jiang J, Mo A, Docking TR, Gharaee N, Li J, Umlandt P, Fuller M, Jädersten M, Kulasekararaj A, Malcovati L, List AF, Hellström-Lindberg E, ... ... Karsan A, et al. Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome. Nature Cell Biology. PMID 32251398 DOI: 10.1038/S41556-020-0497-9 |
0.322 |
|
| 2019 |
Enfield KSS, Marshall EA, Anderson C, Ng KW, Rahmati S, Xu Z, Fuller M, Milne K, Lu D, Shi R, Rowbotham DA, Becker-Santos DD, Johnson FD, English JC, MacAulay CE, ... ... Karsan A, et al. Epithelial tumor suppressor ELF3 is a lineage-specific amplified oncogene in lung adenocarcinoma. Nature Communications. 10: 5438. PMID 31780666 DOI: 10.1038/S41467-019-13295-Y |
0.325 |
|
| 2019 |
Kusakabe M, Sun AC, Tyshchenko K, Wong R, Nanda A, Shanna C, Gusscott S, Chavez EA, Lorzadeh A, Zhu A, Hill A, Hung S, Brown S, Babaian A, Wang X, ... ... Karsan A, et al. Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia. Nature Communications. 10: 2913. PMID 31266935 DOI: 10.1038/S41467-019-10510-8 |
0.35 |
|
| 2019 |
Coulombe P, Paliouras GN, Clayton A, Hussainkhel A, Fuller M, Jovanovic V, Dauphinee S, Umlandt P, Xiang P, Kyle AH, Minchinton AI, Humphries RK, Hoodless PA, Parker JDK, Wright JL, ... Karsan A, et al. Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling. Cell Reports. 27: 1769-1780.e4. PMID 31067462 DOI: 10.1016/J.Celrep.2019.04.039 |
0.386 |
|
| 2019 |
Pender A, Karsan A, Yip S, Bosdet I, Young S, Tucker T, Schrader KA, Sun S. Confirmation of germline variants identified by tumor testing: A population-based study. Journal of Clinical Oncology. 37: e13021-e13021. DOI: 10.1200/Jco.2019.37.15_Suppl.E13021 |
0.301 |
|
| 2019 |
Mo A, Chang L, Duns G, Ibrahim R, Docking R, Umlandt P, Parker J, Karsan A. Loss Of Fbxo11 Functions Drives Acute Myeloid Leukemia Experimental Hematology. 76. DOI: 10.1016/J.Exphem.2019.06.407 |
0.316 |
|
| 2019 |
Coulombe P, Paliouras G, Bilan K, Karsan A. Sash1 Signaling Contributes To The Progression Of The Endothelial-To-Hematopoietic Transition Experimental Hematology. 76. DOI: 10.1016/J.Exphem.2019.06.345 |
0.377 |
|
| 2019 |
Coulombe P, Xiang P, Parker J, Humphries K, Karsan A. MEIS1 EXPRESSION IN MOUSE EMBRYONIC HEMATOPOIESIS Experimental Hematology. 76: S62. DOI: 10.1016/J.Exphem.2019.06.344 |
0.394 |
|
| 2018 |
Alcaide M, Cheung M, Bushell K, Arthur SE, Wong HL, Karasinska J, Renouf D, Schaeffer DF, McNamara S, Tertre MCD, Batist G, Kennecke HF, Karsan A, Morin RD. A Novel Multiplex droplet digital PCR Assay to Identify and Quantify KRAS Mutations in Clinical Specimens. The Journal of Molecular Diagnostics : Jmd. PMID 30472330 DOI: 10.1016/J.Jmoldx.2018.09.007 |
0.3 |
|
| 2018 |
Hui T, Cao Q, Wegrzyn-Woltosz J, O'Neill K, Hammond CA, Knapp DJHF, Laks E, Moksa M, Aparicio S, Eaves CJ, Karsan A, Hirst M. High-Resolution Single-Cell DNA Methylation Measurements Reveal Epigenetically Distinct Hematopoietic Stem Cell Subpopulations. Stem Cell Reports. PMID 30078558 DOI: 10.1016/J.Stemcr.2018.07.003 |
0.304 |
|
| 2018 |
Kusakabe M, Sun AC, Tyshchenko K, Wong R, Nanda A, Shanna C, Gusscott S, Chavez E, Lorzadeh A, Zhu A, Hill A, Hung S, Brown S, Babaian A, Wang X, ... ... Karsan A, et al. Synthetic De Novo Modeling of Human T-Cell Acute Lymphoblastic Leukemia Reveals HOXB Genes Drive Expansion of Leukemia Cells-of-Origin and Established Tumor Clones Blood. 132: 1322-1322. DOI: 10.1182/Blood-2018-99-120120 |
0.354 |
|
| 2018 |
Enfield KSS, Marshall EA, Anderson C, Ng KW, Rahmati S, Xu Z, MacAulay CE, Lam S, Lockwood WW, Chari R, Karsan A, Jurisica I, Lam WL. Abstract A26: Identification of a novel therapeutic target in lung adenocarcinoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-A26 |
0.325 |
|
| 2017 |
Yi Y, Tsai SH, Cheng JC, Wang EY, Anglesio MS, Cochrane DR, Fuller M, Gibb EA, Wei W, Huntsman DG, Karsan A, Hoodless PA. APELA promotes tumour growth and cell migration in ovarian cancer in a p53-dependent manner. Gynecologic Oncology. PMID 29079036 DOI: 10.1016/J.Ygyno.2017.10.016 |
0.302 |
|
| 2017 |
Lai CK, Norddahl GL, Maetzig T, Rosten P, Lohr T, Sanchez Milde L, von Krosigk N, Docking TR, Heuser M, Karsan A, Humphries RK. Meis2 as a critical player in MN1-induced leukemia. Blood Cancer Journal. 7: e613. PMID 28960191 DOI: 10.1038/Bcj.2017.86 |
0.341 |
|
| 2016 |
Lund HL, Hughesman CB, Fakhfakh K, McNeil K, Clemens S, Hocken K, Pettersson R, Karsan A, Foster LJ, Haynes CA. Initial Diagnosis of ALK-positive Non-Small Cell Lung Cancer Based on Analysis of ALK Status Utilizing Droplet Digital PCR. Analytical Chemistry. PMID 27043019 DOI: 10.1021/Acs.Analchem.6B00707 |
0.3 |
|
| 2015 |
Varney ME, Niederkorn M, Konno H, Matsumura T, Gohda J, Yoshida N, Akiyama T, Christie S, Fang J, Miller D, Jerez A, Karsan A, Maciejewski JP, Meetei RA, Inoue J, et al. Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling. The Journal of Experimental Medicine. 212: 1967-85. PMID 26458771 DOI: 10.1084/Jem.20141898 |
0.351 |
|
| 2015 |
Sun H, Savage KJ, Karsan A, Slack GW, Gascoyne RD, Toze CL, Sehn LH, Abou Mourad Y, Barnett MJ, Broady RC, Connors JM, Forrest DL, Gerrie AS, Hogge DE, Narayanan S, et al. Outcome of Patients With Non-Hodgkin Lymphomas With Concurrent MYC and BCL2 Rearrangements Treated With CODOX-M/IVAC With Rituximab Followed by Hematopoietic Stem Cell Transplantation. Clinical Lymphoma, Myeloma & Leukemia. 15: 341-8. PMID 25656914 DOI: 10.1016/J.Clml.2014.12.015 |
0.303 |
|
| 2015 |
Kulic I, Robertson G, Chang L, Baker JH, Lockwood WW, Mok W, Fuller M, Fournier M, Wong N, Chou V, Robinson MD, Chun HJ, Gilks B, Kempkes B, Thomson TA, ... ... Karsan A, et al. Loss of the Notch effector RBPJ promotes tumorigenesis. The Journal of Experimental Medicine. 212: 37-52. PMID 25512468 DOI: 10.1084/Jem.20121192 |
0.346 |
|
| 2015 |
Martinez-Høyer S, Docking R, Chan S, Jadersten M, Parker J, Karsan A. Mechanisms of Resistance to Lenalidomide in Del(5q) Myelodysplastic Syndrome Patients Blood. 126: 5228-5228. DOI: 10.1182/Blood.V126.23.5228.5228 |
0.324 |
|
| 2015 |
Young S, Curman D, Karsan A, Law E, Elemary M, Chalchal H, Zarkovic M. MG-144 When rare happens: Characterising atypical breakpoints in CML Journal of Medical Genetics. 52: A13.1-A13. DOI: 10.1136/Jmedgenet-2015-103577.33 |
0.315 |
|
| 2014 |
Lai CK, Moon Y, Kuchenbauer F, Starzcynowski DT, Argiropoulos B, Yung E, Beer P, Schwarzer A, Sharma A, Park G, Leung M, Lin G, Vollett S, Fung S, Eaves CJ, ... Karsan A, et al. Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene. Plos One. 9: e112671. PMID 25401736 DOI: 10.1371/Journal.Pone.0112671 |
0.341 |
|
| 2014 |
Chang AC, Garside VC, Fournier M, Smrz J, Vrljicak P, Umlandt P, Fuller M, Robertson G, Zhao Y, Tam A, Jones SJ, Marra MA, Hoodless PA, Karsan A. A Notch-dependent transcriptional hierarchy promotes mesenchymal transdifferentiation in the cardiac cushion. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 894-905. PMID 24633789 DOI: 10.1002/Dvdy.24127 |
0.421 |
|
| 2014 |
Patenaude A, Fuller M, Chang L, Wong F, Paliouras G, Shaw R, Kyle AH, Umlandt P, Baker JH, Diaz E, Tong J, Minchinton AI, Karsan A. Endothelial-specific Notch blockade inhibits vascular function and tumor growth through an eNOS-dependent mechanism. Cancer Research. 74: 2402-11. PMID 24599126 DOI: 10.1158/0008-5472.Can-12-4038 |
0.388 |
|
| 2014 |
Mariano C, Bosdet I, Karsan A, Ionescu D, Murray N, Laskin JJ, Zhai Y, Melosky B, Sun S, Ho C. A population-based review of the feasibility of platinum-based combination chemotherapy after tyrosine kinase inhibition in EGFR mutation positive non-small cell lung cancer patients with advanced disease. Lung Cancer (Amsterdam, Netherlands). 83: 73-7. PMID 24192511 DOI: 10.1016/J.Lungcan.2013.10.007 |
0.303 |
|
| 2014 |
Karsan A. miRNAs, Immune Signaling, and Myelodysplastic Syndromes Pathogenesis Blood. 124. DOI: 10.1182/Blood.V124.21.Sci-23.Sci-23 |
0.306 |
|
| 2014 |
Ibrahim R, Wegrzyn J, Chang LY, Umlandt P, Lam J, Fuller M, Karsan A. Activation of Non-Canonical Immune Signalling Pathways Drives Marrow Failure in a Murine Model of MDS Blood. 124: 3246-3246. DOI: 10.1182/Blood.V124.21.3246.3246 |
0.377 |
|
| 2013 |
El-Sehemy A, Chang AC, Azad AK, Gupta N, Xu Z, Steed H, Karsan A, Fu Y. Notch activation augments nitric oxide/soluble guanylyl cyclase signaling in immortalized ovarian surface epithelial cells and ovarian cancer cells. Cellular Signalling. 25: 2780-7. PMID 24041655 DOI: 10.1016/J.Cellsig.2013.09.008 |
0.459 |
|
| 2013 |
Dauphinee SM, Clayton A, Hussainkhel A, Yang C, Park YJ, Fuller ME, Blonder J, Veenstra TD, Karsan A. SASH1 is a scaffold molecule in endothelial TLR4 signaling. Journal of Immunology (Baltimore, Md. : 1950). 191: 892-901. PMID 23776175 DOI: 10.4049/Jimmunol.1200583 |
0.321 |
|
| 2013 |
Chang L, Wong F, Niessen K, Karsan A. Notch activation promotes endothelial survival through a PI3K-Slug axis. Microvascular Research. 89: 80-5. PMID 23743248 DOI: 10.1016/J.Mvr.2013.05.007 |
0.412 |
|
| 2013 |
Chang AC, Patenaude A, Lu K, Fuller M, Ly M, Kyle A, Golbidi S, Wang Y, Walley K, Minchinton A, Laher I, Karsan A. Notch-dependent regulation of the ischemic vasodilatory response--brief report. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 510-2. PMID 23288167 DOI: 10.1161/Atvbaha.112.300840 |
0.422 |
|
| 2013 |
Garside VC, Chang AC, Karsan A, Hoodless PA. Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development. Cellular and Molecular Life Sciences : Cmls. 70: 2899-917. PMID 23161060 DOI: 10.1007/S00018-012-1197-9 |
0.381 |
|
| 2013 |
Fentiman A, Parker J, Swanson L, Mungall K, Birol I, Karsan A. Endothelial-hematopoietic transition: from the dorsal aorta to the dish Experimental Hematology. 41: S26. DOI: 10.1016/J.Exphem.2013.05.104 |
0.31 |
|
| 2012 |
Wong NK, Fuller M, Sung S, Wong F, Karsan A. Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations. Cancer Medicine. 1: 105-13. PMID 23342261 DOI: 10.1002/Cam4.18 |
0.369 |
|
| 2012 |
Vrljicak P, Cullum R, Xu E, Chang AC, Wederell ED, Bilenky M, Jones SJ, Marra MA, Karsan A, Hoodless PA. Twist1 transcriptional targets in the developing atrio-ventricular canal of the mouse. Plos One. 7: e40815. PMID 22815831 DOI: 10.1371/Journal.Pone.0040815 |
0.412 |
|
| 2012 |
Chang L, Noseda M, Higginson M, Ly M, Patenaude A, Fuller M, Kyle AH, Minchinton AI, Puri MC, Dumont DJ, Karsan A. Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling. Proceedings of the National Academy of Sciences of the United States of America. 109: 6993-8. PMID 22509029 DOI: 10.1073/Pnas.1118512109 |
0.396 |
|
| 2012 |
Karsan A. Tumor necrosis factor and endothelial cell death. Trends in Cardiovascular Medicine. 8: 19-24. PMID 21235908 DOI: 10.1016/S1050-1738(97)00126-6 |
0.376 |
|
| 2012 |
Ibrahim R, Woltosz JJW, Starczynowski DT, Umlandt P, Karsan A. Enforced Expression of the Toll/Interleukin-1 Receptor Associated Protein in Murine Marrow Results in MDS-Like Bone Marrow Failure Mediated by Interferon Gamma Blood. 120: 555-555. DOI: 10.1182/Blood.V120.21.555.555 |
0.321 |
|
| 2012 |
Varney M, Jerez A, Fang J, Miller D, Bolanos L, Karsan A, Maciejewski JP, Starczynowski DT. Tifab, a Novel Candidate Gene in Deletion Chromosome 5q, Contributes to Deregulation of NF-κB Signaling in MDS/AML. Blood. 120: 2812-2812. DOI: 10.1182/Blood.V120.21.2812.2812 |
0.361 |
|
| 2011 |
Dauphinee SM, Voelcker V, Tebaykina Z, Wong F, Karsan A. Heterotrimeric Gi/Go proteins modulate endothelial TLR signaling independent of the MyD88-dependent pathway. American Journal of Physiology. Heart and Circulatory Physiology. 301: H2246-53. PMID 21949112 DOI: 10.1152/Ajpheart.01194.2010 |
0.302 |
|
| 2011 |
Starczynowski DT, Lockwood WW, Deléhouzée S, Chari R, Wegrzyn J, Fuller M, Tsao MS, Lam S, Gazdar AF, Lam WL, Karsan A. TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. The Journal of Clinical Investigation. 121: 4095-105. PMID 21911935 DOI: 10.1172/Jci58818 |
0.307 |
|
| 2011 |
Chang AC, Fu Y, Garside VC, Niessen K, Chang L, Fuller M, Setiadi A, Smrz J, Kyle A, Minchinton A, Marra M, Hoodless PA, Karsan A. Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase. Developmental Cell. 21: 288-300. PMID 21839921 DOI: 10.1016/J.Devcel.2011.06.022 |
0.43 |
|
| 2011 |
Fu Y, Chang AC, Fournier M, Chang L, Niessen K, Karsan A. RUNX3 maintains the mesenchymal phenotype after termination of the Notch signal. The Journal of Biological Chemistry. 286: 11803-13. PMID 21288908 DOI: 10.1074/Jbc.M111.222331 |
0.439 |
|
| 2011 |
Patenaude A, Chang L, Diaz E, Fuller M, Wong F, Karsan A. Abstract 3476: Blockade of endothelial Notch diminishes tumor growth and perfusion Cancer Research. 71: 3476-3476. DOI: 10.1158/1538-7445.Am2011-3476 |
0.383 |
|
| 2010 |
Patenaude A, Parker J, Karsan A. Involvement of endothelial progenitor cells in tumor vascularization. Microvascular Research. 79: 217-23. PMID 20085777 DOI: 10.1016/J.Mvr.2010.01.007 |
0.406 |
|
| 2010 |
Vrljicak P, Chang AC, Morozova O, Wederell ED, Niessen K, Marra MA, Karsan A, Hoodless PA. Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal. Physiological Genomics. 40: 150-7. PMID 19952280 DOI: 10.1152/Physiolgenomics.00142.2009 |
0.4 |
|
| 2009 |
Fu Y, Chang A, Chang L, Niessen K, Eapen S, Setiadi A, Karsan A. Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells. The Journal of Biological Chemistry. 284: 19452-62. PMID 19473993 DOI: 10.1074/Jbc.M109.011833 |
0.456 |
|
| 2009 |
Vercauteren SM, Bashashati A, Wu D, Brinkman RR, Eaves C, Eaves A, Karsan A. Reduction in multi-lineage and erythroid progenitors distinguishes myelodysplastic syndromes from non-malignant cytopenias. Leukemia Research. 33: 1636-42. PMID 19414193 DOI: 10.1016/J.Leukres.2009.03.019 |
0.307 |
|
| 2008 |
Niessen K, Fu Y, Chang L, Hoodless PA, McFadden D, Karsan A. Slug is a direct Notch target required for initiation of cardiac cushion cellularization. The Journal of Cell Biology. 182: 315-25. PMID 18663143 DOI: 10.1083/Jcb.200710067 |
0.382 |
|
| 2008 |
Niessen K, Karsan A. Notch signaling in cardiac development. Circulation Research. 102: 1169-81. PMID 18497317 DOI: 10.1161/Circresaha.108.174318 |
0.316 |
|
| 2008 |
Karsan A. Notch and integrin affinity: a sticky situation. Science Signaling. 1: pe2. PMID 18270166 DOI: 10.1126/Stke.12Pe2 |
0.346 |
|
| 2008 |
Wu C, Cipollone J, Maines-Bandiera S, Tan C, Karsan A, Auersperg N, Roskelley CD. The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression. Differentiation; Research in Biological Diversity. 76: 193-205. PMID 17608733 DOI: 10.1111/J.1432-0436.2007.00193.X |
0.32 |
|
| 2007 |
Leong KG, Niessen K, Kulic I, Raouf A, Eaves C, Pollet I, Karsan A. Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. The Journal of Experimental Medicine. 204: 2935-48. PMID 17984306 DOI: 10.1084/Jem.20071082 |
0.326 |
|
| 2007 |
Zhande R, Dauphinee SM, Thomas JA, Yamamoto M, Akira S, Karsan A. FADD negatively regulates lipopolysaccharide signaling by impairing interleukin-1 receptor-associated kinase 1-MyD88 interaction. Molecular and Cellular Biology. 27: 7394-404. PMID 17785432 DOI: 10.1128/Mcb.00600-07 |
0.344 |
|
| 2007 |
Larrivée B, Karsan A. Involvement of marrow-derived endothelial cells in vascularization. Handbook of Experimental Pharmacology. 89-114. PMID 17554506 DOI: 10.1007/978-3-540-68976-8_5 |
0.699 |
|
| 2007 |
Niessen K, Karsan A. Notch signaling in the developing cardiovascular system. American Journal of Physiology. Cell Physiology. 293: C1-11. PMID 17376817 DOI: 10.1152/Ajpcell.00415.2006 |
0.348 |
|
| 2007 |
Zhande R, Karsan A. Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL. American Journal of Physiology. Heart and Circulatory Physiology. 292: H2467-74. PMID 17237249 DOI: 10.1152/Ajpheart.00649.2006 |
0.364 |
|
| 2007 |
Starczynowski DT, Vercauteren S, Telenius A, Sung S, Tohyama K, Brooks-Wilson A, Spinelli JJ, Eaves CJ, Eaves AC, Horsman DE, Lam WL, Karsan A. High-Resolution CGH Analysis of CD34+ Cells from Lower-Risk Myelodysplastic Patients Reveals Cryptic Copy Number Alterations and Predicts Overall and Leukemia-Free Survival. Blood. 110: 2431-2431. DOI: 10.1182/Blood.V110.11.2431.2431 |
0.307 |
|
| 2007 |
Farinha P, Gascoyne RD, Kyle A, Minchinton A, Connors JM, Karsan A. Vascularization Predicts Overall Survival (OS) & Risk of Transformation (RT) in Uniformly Treated Patients with Follicular Lymphoma (FL). Blood. 110: 184-184. DOI: 10.1182/Blood.V110.11.184.184 |
0.31 |
|
| 2006 |
Noseda M, Karsan A. Notch and minichromosome maintenance (MCM) proteins: integration of two ancestral pathways in cell cycle control. Cell Cycle (Georgetown, Tex.). 5: 2704-9. PMID 17172856 DOI: 10.4161/Cc.5.23.3515 |
0.355 |
|
| 2006 |
Larrivée B, Olive PL, Karsan A. Tissue distribution of endothelial cells in vivo following intravenous injection. Experimental Hematology. 34: 1741-5. PMID 17157171 DOI: 10.1016/J.Exphem.2006.08.006 |
0.688 |
|
| 2006 |
Murphy S, Larrivée B, Pollet I, Craig KS, Williams DE, Huang XH, Abbott M, Wong F, Curtis C, Conrads TP, Veenstra T, Puri M, Hsiang Y, Roberge M, Andersen RJ, ... Karsan A, et al. Identification of sokotrasterol sulfate as a novel proangiogenic steroid. Circulation Research. 99: 257-65. PMID 16794189 DOI: 10.1161/01.Res.0000233316.17882.33 |
0.352 |
|
| 2006 |
Noseda M, Fu Y, Niessen K, Wong F, Chang L, McLean G, Karsan A. Smooth Muscle alpha-actin is a direct target of Notch/CSL. Circulation Research. 98: 1468-70. PMID 16741155 DOI: 10.1161/01.Res.0000229683.81357.26 |
0.362 |
|
| 2006 |
Dauphinee SM, Karsan A. Lipopolysaccharide signaling in endothelial cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 9-22. PMID 16357866 DOI: 10.1038/Labinvest.3700366 |
0.358 |
|
| 2006 |
Leong KG, Karsan A. Recent insights into the role of Notch signaling in tumorigenesis. Blood. 107: 2223-33. PMID 16291593 DOI: 10.1182/Blood-2005-08-3329 |
0.337 |
|
| 2005 |
Larrivée B, Pollet I, Karsan A. Activation of vascular endothelial growth factor receptor-2 in bone marrow leads to accumulation of myeloid cells: role of granulocyte-macrophage colony-stimulating factor. Journal of Immunology (Baltimore, Md. : 1950). 175: 3015-24. PMID 16116189 DOI: 10.4049/Jimmunol.175.5.3015 |
0.708 |
|
| 2005 |
Larrivée B, Niessen K, Pollet I, Corbel SY, Long M, Rossi FM, Olive PL, Karsan A. Minimal contribution of marrow-derived endothelial precursors to tumor vasculature. Journal of Immunology (Baltimore, Md. : 1950). 175: 2890-9. PMID 16116175 DOI: 10.4049/Jimmunol.175.5.2890 |
0.415 |
|
| 2005 |
Harfouche R, Malak NA, Brandes RP, Karsan A, Irani K, Hussain SN. Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 1728-30. PMID 16049136 DOI: 10.1096/Fj.04-3621Fje |
0.328 |
|
| 2005 |
Noseda M, Niessen K, McLean G, Chang L, Karsan A. Notch-dependent cell cycle arrest is associated with downregulation of minichromosome maintenance proteins. Circulation Research. 97: 102-4. PMID 15976316 DOI: 10.1161/01.Res.0000174380.06673.81 |
0.388 |
|
| 2005 |
Karsan A, Blonder J, Law J, Yaquian E, Lucas DA, Conrads TP, Veenstra T. Proteomic analysis of lipid microdomains from lipopolysaccharide-activated human endothelial cells. Journal of Proteome Research. 4: 349-57. PMID 15822910 DOI: 10.1021/Pr049824W |
0.313 |
|
| 2005 |
Karsan A. The role of notch in modeling and maintaining the vasculature. Canadian Journal of Physiology and Pharmacology. 83: 14-23. PMID 15759046 DOI: 10.1139/Y04-125 |
0.371 |
|
| 2005 |
Karsan A, Pollet I, Yu LR, Chan KC, Conrads TP, Lucas DA, Andersen R, Veenstra T. Quantitative proteomic analysis of sokotrasterol sulfate-stimulated primary human endothelial cells. Molecular & Cellular Proteomics : McP. 4: 191-204. PMID 15611527 DOI: 10.1074/Mcp.M400152-Mcp200 |
0.408 |
|
| 2005 |
Larrivée B, Karsan A. Isolation and culture of primary endothelial cells. Methods in Molecular Biology (Clifton, N.J.). 290: 315-29. PMID 15361671 DOI: 10.1385/1-59259-838-2:315 |
0.676 |
|
| 2004 |
Noseda M, Chang L, McLean G, Grim JE, Clurman BE, Smith LL, Karsan A. Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Molecular and Cellular Biology. 24: 8813-22. PMID 15456857 DOI: 10.1128/Mcb.24.20.8813-8822.2004 |
0.418 |
|
| 2004 |
MacKenzie F, Duriez P, Larrivée B, Chang L, Pollet I, Wong F, Yip C, Karsan A. Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-Jkappa. Blood. 104: 1760-8. PMID 15187023 DOI: 10.1182/Blood-2003-12-4244 |
0.695 |
|
| 2004 |
Wong F, Hull C, Zhande R, Law J, Karsan A. Lipopolysaccharide initiates a TRAF6-mediated endothelial survival signal. Blood. 103: 4520-6. PMID 14996708 DOI: 10.1182/Blood-2003-06-2118 |
0.359 |
|
| 2004 |
Noseda M, McLean G, Niessen K, Chang L, Pollet I, Montpetit R, Shahidi R, Dorovini-Zis K, Li L, Beckstead B, Durand RE, Hoodless PA, Karsan A. Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circulation Research. 94: 910-7. PMID 14988227 DOI: 10.1161/01.Res.0000124300.76171.C9 |
0.413 |
|
| 2004 |
MacKenzie F, Duriez P, Wong F, Noseda M, Karsan A. Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways. The Journal of Biological Chemistry. 279: 11657-63. PMID 14701863 DOI: 10.1074/Jbc.M312102200 |
0.394 |
|
| 2004 |
Larrivee B, Pollet I, Karsan A. Activation of VEGFR-2 in Hematopoietic Progenitor Cells Leads to Accumulation of Myeloid Cells through Up-Regulation of GM-CSF. Blood. 104: 1474-1474. DOI: 10.1182/Blood.V104.11.1474.1474 |
0.706 |
|
| 2003 |
Harfouche R, Gratton JP, Yancopoulos GD, Noseda M, Karsan A, Hussain SNA. Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1523-1525. PMID 12824293 DOI: 10.1096/Fj.02-0698Fje |
0.337 |
|
| 2003 |
Pollet I, Opina CJ, Zimmerman C, Leong KG, Wong F, Karsan A. Bacterial lipopolysaccharide directly induces angiogenesis through TRAF6-mediated activation of NF-kappaB and c-Jun N-terminal kinase. Blood. 102: 1740-2. PMID 12714497 DOI: 10.1182/Blood-2003-01-0288 |
0.338 |
|
| 2003 |
Larrivée B, Lane DR, Pollet I, Olive PL, Humphries RK, Karsan A. Vascular endothelial growth factor receptor-2 induces survival of hematopoietic progenitor cells. The Journal of Biological Chemistry. 278: 22006-13. PMID 12668684 DOI: 10.1074/Jbc.M212158200 |
0.706 |
|
| 2003 |
Levkau B, Kenagy RD, Karsan A, Weitkamp B, Clowes AW, Ross R, Raines EW. Activation of metalloproteinases and their association with integrins: an auxiliary apoptotic pathway in human endothelial cells. Cell Death and Differentiation. 9: 1360-7. PMID 12478473 DOI: 10.1038/Sj.Cdd.4401106 |
0.341 |
|
| 2002 |
Hull C, McLean G, Wong F, Duriez PJ, Karsan A. Lipopolysaccharide signals an endothelial apoptosis pathway through TNF receptor-associated factor 6-mediated activation of c-Jun NH2-terminal kinase. Journal of Immunology (Baltimore, Md. : 1950). 169: 2611-8. PMID 12193732 DOI: 10.4049/Jimmunol.169.5.2611 |
0.312 |
|
| 2002 |
Litwin C, Leong KG, Zapf R, Sutherland H, Naiman SC, Karsan A. Role of the microenvironment in promoting angiogenesis in acute myeloid leukemia. American Journal of Hematology. 70: 22-30. PMID 11994978 DOI: 10.1002/Ajh.10092 |
0.388 |
|
| 2002 |
Leong KG, Hu X, Li L, Noseda M, Larrivée B, Hull C, Hood L, Wong F, Karsan A. Activated Notch4 inhibits angiogenesis: role of beta 1-integrin activation. Molecular and Cellular Biology. 22: 2830-41. PMID 11909975 DOI: 10.1128/Mcb.22.8.2830-2841.2002 |
0.397 |
|
| 2000 |
Leong KG, Karsan A. Signaling pathways mediated by tumor necrosis factor alpha. Histology and Histopathology. 15: 1303-1325. PMID 11005254 DOI: 10.14670/Hh-15.1303 |
0.359 |
|
| 2000 |
Duriez PJ, Wong F, Dorovini-Zis K, Shahidi R, Karsan A. A1 functions at the mitochondria to delay endothelial apoptosis in response to tumor necrosis factor. The Journal of Biological Chemistry. 275: 18099-107. PMID 10849436 DOI: 10.1074/Jbc.M908925199 |
0.301 |
|
| 2000 |
Larrivée B, Karsan A. Signaling pathways induced by vascular endothelial growth factor (review). International Journal of Molecular Medicine. 5: 447-56. PMID 10762646 DOI: 10.3892/Ijmm.5.5.447 |
0.691 |
|
| 1999 |
Stempien-Otero A, Karsan A, Cornejo CJ, Xiang H, Eunson T, Morrison RS, Kay M, Winn R, Harlan J. Mechanisms of hypoxia-induced endothelial cell death. Role of p53 in apoptosis. The Journal of Biological Chemistry. 274: 8039-45. PMID 10075703 DOI: 10.1074/Jbc.274.12.8039 |
0.371 |
|
| 1998 |
Mitra D, Kim J, MacLow C, Karsan A, Laurence J. Role of caspases 1 and 3 and Bcl-2-related molecules in endothelial cell apoptosis associated with thrombotic microangiopathies. American Journal of Hematology. 59: 279-87. PMID 9840908 DOI: 10.1002/(Sici)1096-8652(199812)59:4<279::Aid-Ajh3>3.0.Co;2-J |
0.312 |
|
| 1998 |
Chuang PI, Yee E, Karsan A, Winn RK, Harlan JM. A1 is a constitutive and inducible Bcl-2 homologue in mature human neutrophils. Biochemical and Biophysical Research Communications. 249: 361-5. PMID 9712701 DOI: 10.1006/Bbrc.1998.9155 |
0.301 |
|
| 1998 |
Choi KB, Wong F, Harlan JM, Chaudhary PM, Hood L, Karsan A. Lipopolysaccharide mediates endothelial apoptosis by a FADD-dependent pathway. The Journal of Biological Chemistry. 273: 20185-8. PMID 9685365 DOI: 10.1074/Jbc.273.32.20185 |
0.35 |
|
| 1998 |
Karsan A, Cornejo CJ, Winn RK, Schwartz BR, Way W, Lannir N, Gershoni-Baruch R, Etzioni A, Ochs HD, Harlan JM. Leukocyte Adhesion Deficiency Type II is a generalized defect of de novo GDP-fucose biosynthesis. Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium. The Journal of Clinical Investigation. 101: 2438-45. PMID 9616215 DOI: 10.1172/Jci905 |
0.353 |
|
| 1998 |
Hu X, Yee E, Harlan JM, Wong F, Karsan A. Lipopolysaccharide Induces the Antiapoptotic Molecules, A1 and A20, in Microvascular Endothelial Cells Blood. 92: 2759-2765. DOI: 10.1182/Blood.V92.8.2759 |
0.306 |
|
| 1997 |
Karsan A, Harlan JM. Modulation of endothelial cell apoptosis: mechanisms and pathophysiological roles. Journal of Atherosclerosis and Thrombosis. 3: 75-80. PMID 9226458 DOI: 10.5551/Jat1994.3.75 |
0.344 |
|
| 1997 |
Bombeli T, Karsan A, Tait JF, Harlan JM. Apoptotic Vascular Endothelial Cells Become Procoagulant Blood. 89: 2429-2442. DOI: 10.1182/Blood.V89.7.2429 |
0.389 |
|
| 1996 |
Karsan A, Yee E, Harlan JM. Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1. The Journal of Biological Chemistry. 271: 27201-4. PMID 8910286 DOI: 10.1074/Jbc.271.44.27201 |
0.375 |
|
| 1996 |
Karsan A, Yee E, Kaushansky K, Harlan JM. Cloning of human Bcl-2 homologue: inflammatory cytokines induce human A1 in cultured endothelial cells. Blood. 87: 3089-96. PMID 8605321 DOI: 10.1182/Blood.V87.8.3089.Bloodjournal8783089 |
0.382 |
|
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