| Year |
Citation |
Score |
| 2019 |
Zachariah S, Gray DA. Deubiquitinating Enzymes in Model Systems and Therapy: Redundancy and Compensation Have Implications. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1900112. PMID 31544968 DOI: 10.1002/Bies.201900112 |
0.305 |
|
| 2018 |
Boisvert NC, Holterman CE, Gutsol A, Coulombe J, Pan W, Alexander RT, Gray DA, Kennedy CR. Ubiquitin C-terminal hydrolase L1 deletion is associated with urinary α-klotho deficiency and perturbed phosphate homeostasis. American Journal of Physiology. Renal Physiology. PMID 29667913 DOI: 10.1152/Ajprenal.00411.2017 |
0.301 |
|
| 2017 |
Clark-Knowles KV, He X, Jardine K, Coulombe J, Dewar-Darch D, Caron AZ, Gray DA, McBurney MW. Reversible modulation of SIRT1 activity in a mouse strain. Plos One. 12: e0173002. PMID 28273169 DOI: 10.1371/Journal.Pone.0173002 |
0.343 |
|
| 2015 |
Vlasschaert C, Xia X, Coulombe J, Gray DA. Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11. Bmc Evolutionary Biology. 15: 230. PMID 26503449 DOI: 10.1186/S12862-015-0511-1 |
0.33 |
|
| 2015 |
Wilson CL, Murphy LB, Leslie J, Kendrick S, French J, Fox CR, Sheerin NS, Fisher A, Robinson JH, Tiniakos DG, Gray DA, Oakley F, Mann DA. Ubiquitin C-Terminal Hydrolase 1 (UCHL1); A Novel Functional Marker for Liver Myofibroblasts and a Therapeutic Target in Chronic Liver Disease. Journal of Hepatology. PMID 26264933 DOI: 10.1016/J.Jhep.2015.07.034 |
0.34 |
|
| 2015 |
Radwan M, Wilkinson DJ, Hui W, Destrument AP, Charlton SH, Barter MJ, Gibson B, Coulombe J, Gray DA, Rowan AD, Young DA. Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination. Annals of the Rheumatic Diseases. 74: 1580-7. PMID 24713355 DOI: 10.1136/Annrheumdis-2013-204962 |
0.324 |
|
| 2014 |
Coulombe J, Gamage P, Gray MT, Zhang M, Tang MY, Woulfe J, Saffrey MJ, Gray DA. Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system. Frontiers in Aging Neuroscience. 6: 129. PMID 24994982 DOI: 10.3389/Fnagi.2014.00129 |
0.325 |
|
| 2014 |
Woulfe JM, Gray MT, Gray DA, Munoz DG, Middeldorp JM. Hypothesis: a role for EBV-induced molecular mimicry in Parkinson's disease. Parkinsonism & Related Disorders. 20: 685-94. PMID 24726430 DOI: 10.1016/J.Parkreldis.2014.02.031 |
0.326 |
|
| 2014 |
Read NC, Gutsol A, Holterman CE, Carter A, Coulombe J, Gray DA, Kennedy CR. Ubiquitin C-terminal hydrolase L1 deletion ameliorates glomerular injury in mice with ACTN4-associated focal segmental glomerulosclerosis. Biochimica Et Biophysica Acta. 1842: 1028-40. PMID 24662305 DOI: 10.1016/J.Bbadis.2014.03.009 |
0.346 |
|
| 2013 |
McBurney MW, Clark-Knowles KV, Caron AZ, Gray DA. SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress. Genes & Cancer. 4: 125-34. PMID 24020004 DOI: 10.1177/1947601912474893 |
0.381 |
|
| 2013 |
Gray DA, Woulfe J. Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease. Frontiers in Genetics. 4: 149. PMID 23967011 DOI: 10.3389/Fgene.2013.00149 |
0.326 |
|
| 2010 |
Tang MY, Proctor CJ, Woulfe J, Gray DA. Experimental and computational analysis of polyglutamine-mediated cytotoxicity. Plos Computational Biology. 6. PMID 20885783 DOI: 10.1371/Journal.Pcbi.1000944 |
0.352 |
|
| 2010 |
Baldwin RM, Barrett GM, Parolin DA, Gillies JK, Paget JA, Lavictoire SJ, Gray DA, Lorimer IA. Coordination of glioblastoma cell motility by PKCι. Molecular Cancer. 9: 233. PMID 20815904 DOI: 10.1186/1476-4598-9-233 |
0.323 |
|
| 2010 |
Brun J, Chiu RK, Wouters BG, Gray DA. Regulation of PCNA polyubiquitination in human cells. Bmc Research Notes. 3: 85. PMID 20353596 DOI: 10.1186/1756-0500-3-85 |
0.309 |
|
| 2010 |
Proctor CJ, Gray DA. GSK3 and p53 - is there a link in Alzheimer's disease? Molecular Neurodegeneration. 5: 7. PMID 20181016 DOI: 10.1186/1750-1326-5-7 |
0.337 |
|
| 2010 |
Woulfe J, Gray DA, Mackenzie IR. FUS-immunoreactive intranuclear inclusions in neurodegenerative disease. Brain Pathology (Zurich, Switzerland). 20: 589-97. PMID 19832837 DOI: 10.1111/J.1750-3639.2009.00337.X |
0.327 |
|
| 2010 |
Abedini MR, Muller EJ, Bergeron R, Gray DA, Tsang BK. Akt promotes chemoresistance in human ovarian cancer cells by modulating cisplatin-induced, p53-dependent ubiquitination of FLICE-like inhibitory protein. Oncogene. 29: 11-25. PMID 19802016 DOI: 10.1038/Onc.2009.300 |
0.338 |
|
| 2009 |
Brun J, Gray DA. Targeting the ubiquitin proteasome pathway for the treatment of septic shock in patients. Critical Care (London, England). 13: 311. PMID 19691815 DOI: 10.1186/Cc7946 |
0.311 |
|
| 2009 |
Lorimer IAJ, Gray DA, Baldwin M. Abstract B223: Protein kinase C iota as a target for glioblastoma therapy Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B223 |
0.335 |
|
| 2008 |
Proctor CJ, Gray DA. Explaining oscillations and variability in the p53-Mdm2 system. Bmc Systems Biology. 2: 75. PMID 18706112 DOI: 10.1186/1752-0509-2-75 |
0.307 |
|
| 2008 |
Abedini MR, Muller EJ, Brun J, Bergeron R, Gray DA, Tsang BK. Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells. Cancer Research. 68: 4511-7. PMID 18559494 DOI: 10.1158/0008-5472.Can-08-0673 |
0.337 |
|
| 2008 |
Tsirigotis M, Baldwin RM, Tang MY, Lorimer IA, Gray DA. Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity. Plos One. 3: e2130. PMID 18461158 DOI: 10.1371/Journal.Pone.0002130 |
0.316 |
|
| 2008 |
Brun J, Chiu R, Lockhart K, Xiao W, Wouters BG, Gray DA. hMMS2 serves a redundant role in human PCNA polyubiquitination. Bmc Molecular Biology. 9: 24. PMID 18284681 DOI: 10.1186/1471-2199-9-24 |
0.329 |
|
| 2007 |
Proctor CJ, Tsirigotis M, Gray DA. An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline. Bmc Systems Biology. 1: 17. PMID 17408507 DOI: 10.1186/1752-0509-1-17 |
0.358 |
|
| 2007 |
Langie SA, Knaapen AM, Ramaekers CH, Theys J, Brun J, Godschalk RW, van Schooten FJ, Lambin P, Gray DA, Wouters BG, Chiu RK. Formation of lysine 63-linked poly-ubiquitin chains protects human lung cells against benzo[a]pyrene-diol-epoxide-induced mutagenicity. Dna Repair. 6: 852-62. PMID 17395554 DOI: 10.1016/J.Dnarep.2007.02.012 |
0.334 |
|
| 2006 |
Chiu RK, Brun J, Ramaekers C, Theys J, Weng L, Lambin P, Gray DA, Wouters BG. Lysine 63-polyubiquitination guards against translesion synthesis-induced mutations. Plos Genetics. 2: e116. PMID 16789823 DOI: 10.1371/Journal.Pgen.0020116 |
0.316 |
|
| 2006 |
Tsirigotis M, Tang MY, Beyers M, Zhang M, Woulfe J, Gray DA. Delayed spinocerebellar ataxia in transgenic mice expressing mutant ubiquitin. Neuropathology and Applied Neurobiology. 32: 26-39. PMID 16409551 DOI: 10.1111/J.1365-2990.2005.00694.X |
0.4 |
|
| 2005 |
Gray DA, Woulfe J. Lipofuscin and aging: a matter of toxic waste. Science of Aging Knowledge Environment : Sage Ke. 2005: re1. PMID 15689603 DOI: 10.1126/Sageke.2005.5.Re1 |
0.324 |
|
| 2005 |
Gilchrist CA, Gray DA, Stieber A, Gonatas NK, Kopito RR. Effect of ubiquitin expression on neuropathogenesis in a mouse model of familial amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology. 31: 20-33. PMID 15634228 DOI: 10.1111/J.1365-2990.2004.00604.X |
0.345 |
|
| 2004 |
Gray DA, Tsirigotis M, Brun J, Tang M, Zhang M, Beyers M, Woulfe J. Protective effects of mutant ubiquitin in transgenic mice. Annals of the New York Academy of Sciences. 1019: 215-8. PMID 15247017 DOI: 10.1196/Annals.1297.035 |
0.328 |
|
| 2004 |
Hyun DH, Gray DA, Halliwell B, Jenner P. Interference with ubiquitination causes oxidative damage and increased protein nitration: implications for neurodegenerative diseases. Journal of Neurochemistry. 90: 422-30. PMID 15228598 DOI: 10.1111/J.1471-4159.2004.02493.X |
0.355 |
|
| 2003 |
Rasoulpour RJ, Schoenfeld HA, Gray DA, Boekelheide K. Expression of a K48R mutant ubiquitin protects mouse testis from cryptorchid injury and aging. The American Journal of Pathology. 163: 2595-603. PMID 14633631 DOI: 10.1016/S0002-9440(10)63614-0 |
0.343 |
|
| 2003 |
Gray DA, Tsirigotis M, Woulfe J. Ubiquitin, proteasomes, and the aging brain. Science of Aging Knowledge Environment : Sage Ke. 2003: RE6. PMID 12944592 DOI: 10.1126/Sageke.2003.34.Re6 |
0.324 |
|
| 2003 |
Zhang M, Thurig S, Tsirigotis M, Wong PK, Reuhl KR, Gray DA. Effects of mutant ubiquitin on ts1 retrovirus-mediated neuropathology. Journal of Virology. 77: 7193-201. PMID 12805418 DOI: 10.1128/Jvi.77.13.7193-7201.2003 |
0.349 |
|
| 2001 |
Tsirigotis M, Zhang M, Chiu RK, Wouters BG, Gray DA. Sensitivity of mammalian cells expressing mutant ubiquitin to protein-damaging agents. The Journal of Biological Chemistry. 276: 46073-8. PMID 11598140 DOI: 10.1074/Jbc.M109023200 |
0.385 |
|
| 2001 |
Blanchette P, Gilchrist CA, Baker RT, Gray DA. Association of UNP, a ubiquitin-specific protease, with the pocket proteins pRb, p107 and p130. Oncogene. 20: 5533-7. PMID 11571651 DOI: 10.1038/Sj.Onc.1204823 |
0.652 |
|
| 2001 |
Tsirigotis M, Thurig S, Dubé M, Vanderhyden BC, Zhang M, Gray DA. Analysis of ubiquitination in vivo using a transgenic mouse model. Biotechniques. 31: 120-6, 128, 130. PMID 11464505 DOI: 10.2144/01311Rr03 |
0.393 |
|
| 2001 |
Gray DA. Damage control--a possible non-proteolytic role for ubiquitin in limiting neurodegeneration. Neuropathology and Applied Neurobiology. 27: 89-94. PMID 11437989 DOI: 10.1046/J.1365-2990.2001.00321.X |
0.368 |
|
| 1999 |
Abraham N, Stojdl DF, Duncan PI, Méthot N, Ishii T, Dubé M, Vanderhyden BC, Atkins HL, Gray DA, McBurney MW, Koromilas AE, Brown EG, Sonenberg N, Bell JC. Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR Journal of Biological Chemistry. 274: 5953-5962. PMID 10026221 DOI: 10.1074/Jbc.274.9.5953 |
0.354 |
|
| 1997 |
Gilchrist CA, Gray DA, Baker RT. A ubiquitin-specific protease that efficiently cleaves the ubiquitin-proline bond. The Journal of Biological Chemistry. 272: 32280-5. PMID 9405433 DOI: 10.1074/Jbc.272.51.32280 |
0.343 |
|
| 1997 |
Di Fruscio M, Weiher H, Vanderhyden BC, Imai T, Shiomi T, Hori TA, Jaenisch R, Gray DA. Proviral inactivation of the Npat gene of Mpv 20 mice results in early embryonic arrest. Molecular and Cellular Biology. 17: 4080-6. PMID 9199343 DOI: 10.1128/Mcb.17.7.4080 |
0.31 |
|
| 1996 |
Coulombe J, Avis Y, Gray DA. A replication-competent promoter-trap retrovirus Journal of Virology. 70: 6810-6815. PMID 8794320 DOI: 10.1128/Jvi.70.10.6810-6815.1996 |
0.304 |
|
| 1994 |
Coulombe J, Dube M, Gray DA. Replication of a Moloney Murine Leukemia Virus Mutant Lacking the ELP Binding Site Virology. 203: 162-165. PMID 8030273 DOI: 10.1006/Viro.1994.1468 |
0.303 |
|
| 1991 |
Johnson P, Gray D, Mowat M, Benchimol S. Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells. Molecular and Cellular Biology. 11: 1-11. PMID 1986214 DOI: 10.1128/Mcb.11.1.1 |
0.358 |
|
| 1990 |
Weiher H, Noda T, Gray DA, Sharpe AH, Jaenisch R. Transgenic mouse model of kidney disease: Insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome Cell. 62: 425-434. PMID 1696177 DOI: 10.1016/0092-8674(90)90008-3 |
0.31 |
|
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