Robert L. Garcea - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Molecular Biology, Virology Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Peters DK, Erickson KD, Garcea RL. Live Cell Microscopy of Murine Polyomavirus Subnuclear Replication Centers. Viruses. 12. PMID 33023278 DOI: 10.3390/v12101123  0.371
2020 Peters DK, Garcea RL. Murine polyomavirus DNA transitions through spatially distinct nuclear replication subdomains during infection. Plos Pathogens. 16: e1008403. PMID 32203554 DOI: 10.1371/Journal.Ppat.1008403  0.414
2019 Broniarczyk J, Massimi P, Pim D, Bergant Marušič M, Myers MP, Garcea RL, Banks L. Phosphorylation of HPV-16 L2 Contributes To Efficient Virus Infectious Entry. Journal of Virology. PMID 30996086 DOI: 10.1128/Jvi.00128-19  0.4
2019 Erickson KD, Garcea RL. Viral replication centers and the DNA damage response in JC virus-infected cells. Virology. 528: 198-206. PMID 30811999 DOI: 10.1016/J.Virol.2018.12.014  0.436
2016 O'Hara SD, Garcea RL. Murine Polyomavirus Cell Surface Receptors Activate Distinct Signaling Pathways Required for Infection. Mbio. 7. PMID 27803182 DOI: 10.1128/Mbio.01836-16  0.353
2016 Heiser K, Nicholas C, Garcea RL. Activation of DNA damage repair pathways by murine polyomavirus. Virology. 497: 346-356. PMID 27529739 DOI: 10.1016/J.Virol.2016.07.028  0.401
2015 You J, O'Hara SD, Velupillai P, Castle S, Levery S, Garcea RL, Benjamin T. Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus. Plos Pathogens. 11: e1005175. PMID 26474471 DOI: 10.1371/Journal.Ppat.1005175  0.41
2015 Buch MH, Liaci AM, O'Hara SD, Garcea RL, Neu U, Stehle T. Structural and Functional Analysis of Murine Polyomavirus Capsid Proteins Establish the Determinants of Ligand Recognition and Pathogenicity. Plos Pathogens. 11: e1005104. PMID 26474293 DOI: 10.1371/Journal.Ppat.1005104  0.322
2015 Berrios C, Jung J, Primi B, Wang M, Pedamallu C, Duke F, Marcelus C, Cheng J, Garcea RL, Meyerson M, DeCaprio JA. Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors. Journal of Virology. 89: 857-62. PMID 25320321 DOI: 10.1128/Jvi.02328-14  0.398
2014 Sospedra M, Schippling S, Yousef S, Jelcic I, Bofill-Mas S, Planas R, Stellmann JP, Demina V, Cinque P, Garcea R, Croughs T, Girones R, Martin R. Treating progressive multifocal leukoencephalopathy with interleukin 7 and vaccination with JC virus capsid protein VP1. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 59: 1588-92. PMID 25214510 DOI: 10.1093/Cid/Ciu682  0.387
2014 Ströh LJ, Neu U, Blaum BS, Buch MH, Garcea RL, Stehle T. Structure analysis of the major capsid proteins of human polyomaviruses 6 and 7 reveals an obstructed sialic acid binding site. Journal of Virology. 88: 10831-9. PMID 25008942 DOI: 10.1128/Jvi.01084-14  0.378
2014 O'Hara SD, Stehle T, Garcea R. Glycan receptors of the Polyomaviridae: structure, function, and pathogenesis. Current Opinion in Virology. 7: 73-8. PMID 24983512 DOI: 10.1016/J.Coviro.2014.05.004  0.346
2013 Raval FM, Mishra R, Garcea RL, Welsh RM, Szomolanyi-Tsuda E. Long-lasting T cell-independent IgG responses require MyD88-mediated pathways and are maintained by high levels of virus persistence. Mbio. 4: e00812-13. PMID 24194540 DOI: 10.1128/Mbio.00812-13  0.339
2013 DeCaprio JA, Garcea RL. A cornucopia of human polyomaviruses. Nature Reviews. Microbiology. 11: 264-76. PMID 23474680 DOI: 10.1038/Nrmicro2992  0.322
2012 Neu U, Hengel H, Blaum BS, Schowalter RM, Macejak D, Gilbert M, Wakarchuk WW, Imamura A, Ando H, Kiso M, Arnberg N, Garcea RL, Peters T, Buck CB, Stehle T. Structures of Merkel cell polyomavirus VP1 complexes define a sialic acid binding site required for infection. Plos Pathogens. 8: e1002738. PMID 22910713 DOI: 10.1371/Journal.Ppat.1002738  0.388
2012 Bienkowska-Haba M, Williams C, Kim SM, Garcea RL, Sapp M. Cyclophilins facilitate dissociation of the human papillomavirus type 16 capsid protein L1 from the L2/DNA complex following virus entry. Journal of Virology. 86: 9875-87. PMID 22761365 DOI: 10.1128/Jvi.00980-12  0.354
2012 Magaldi TG, Buch MH, Murata H, Erickson KD, Neu U, Garcea RL, Peden K, Stehle T, DiMaio D. Mutations in the GM1 binding site of simian virus 40 VP1 alter receptor usage and cell tropism. Journal of Virology. 86: 7028-42. PMID 22514351 DOI: 10.1128/Jvi.00371-12  0.387
2012 Erickson KD, Bouchet-Marquis C, Heiser K, Szomolanyi-Tsuda E, Mishra R, Lamothe B, Hoenger A, Garcea RL. Virion assembly factories in the nucleus of polyomavirus-infected cells. Plos Pathogens. 8: e1002630. PMID 22496654 DOI: 10.1371/Journal.Ppat.1002630  0.487
2011 Neu U, Wang J, Macejak D, Garcea RL, Stehle T. Structures of the major capsid proteins of the human Karolinska Institutet and Washington University polyomaviruses. Journal of Virology. 85: 7384-92. PMID 21543504 DOI: 10.1128/Jvi.00382-11  0.453
2010 Jagu S, Kwak K, Garcea RL, Roden RB. Vaccination with multimeric L2 fusion protein and L1 VLP or capsomeres to broaden protection against HPV infection. Vaccine. 28: 4478-86. PMID 20434552 DOI: 10.1016/J.Vaccine.2010.04.039  0.315
2010 Wolf M, Garcea RL, Grigorieff N, Harrison SC. Subunit interactions in bovine papillomavirus. Proceedings of the National Academy of Sciences of the United States of America. 107: 6298-303. PMID 20308582 DOI: 10.1073/Pnas.0914604107  0.359
2009 Bazan SB, de Alencar Muniz Chaves A, Aires KA, Cianciarullo AM, Garcea RL, Ho PL. Expression and characterization of HPV-16 L1 capsid protein in Pichia pastoris. Archives of Virology. 154: 1609-17. PMID 19756360 DOI: 10.1007/S00705-009-0484-8  0.38
2009 Erickson KD, Garcea RL, Tsai B. Ganglioside GT1b is a putative host cell receptor for the Merkel cell polyomavirus. Journal of Virology. 83: 10275-9. PMID 19605473 DOI: 10.1128/Jvi.00949-09  0.303
2009 Guay HM, Mishra R, Garcea RL, Welsh RM, Szomolanyi-Tsuda E. Generation of protective T cell-independent antiviral antibody responses in SCID mice reconstituted with follicular or marginal zone B cells. Journal of Immunology (Baltimore, Md. : 1950). 183: 518-23. PMID 19542462 DOI: 10.4049/Jimmunol.0900068  0.328
2009 Dalianis T, Ramqvist T, Andreasson K, Kean JM, Garcea RL. KI, WU and Merkel cell polyomaviruses: a new era for human polyomavirus research. Seminars in Cancer Biology. 19: 270-5. PMID 19416753 DOI: 10.1016/J.Semcancer.2009.04.001  0.328
2009 Kean JM, Rao S, Wang M, Garcea RL. Seroepidemiology of human polyomaviruses. Plos Pathogens. 5: e1000363. PMID 19325891 DOI: 10.1371/Journal.Ppat.1000363  0.407
2008 Bird G, O'Donnell M, Moroianu J, Garcea RL. Possible role for cellular karyopherins in regulating polyomavirus and papillomavirus capsid assembly. Journal of Virology. 82: 9848-57. PMID 18701594 DOI: 10.1128/Jvi.01221-08  0.415
2008 Garcea RL. Biologic Constraints on Modelling Virus Assembly Computational and Mathematical Methods in Medicine. 9: 257-264. DOI: 10.1080/17486700802168007  0.466
2007 Bishop B, Dasgupta J, Klein M, Garcea RL, Christensen ND, Zhao R, Chen XS. Crystal structures of four types of human papillomavirus L1 capsid proteins: understanding the specificity of neutralizing monoclonal antibodies. The Journal of Biological Chemistry. 282: 31803-11. PMID 17804402 DOI: 10.1074/Jbc.M706380200  0.303
2007 Guay HM, Andreyeva TA, Garcea RL, Welsh RM, Szomolanyi-Tsuda E. MyD88 is required for the formation of long-term humoral immunity to virus infection. Journal of Immunology (Baltimore, Md. : 1950). 178: 5124-31. PMID 17404295 DOI: 10.4049/Jimmunol.178.8.5124  0.32
2006 Szomolanyi-Tsuda E, Seedhom MO, Carroll MC, Garcea RL. T cell-independent and T cell-dependent immunoglobulin G responses to polyomavirus infection are impaired in complement receptor 2-deficient mice. Virology. 352: 52-60. PMID 16733062 DOI: 10.1016/J.Virol.2006.04.018  0.34
2006 Chromy LR, Oltman A, Estes PA, Garcea RL. Chaperone-mediated in vitro disassembly of polyoma- and papillomaviruses. Journal of Virology. 80: 5086-91. PMID 16641302 DOI: 10.1128/Jvi.80.10.5086-5091.2006  0.666
2006 Velupillai P, Garcea RL, Benjamin TL. Polyoma virus-like particles elicit polarized cytokine responses in APCs from tumor-susceptible and -resistant mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 1148-53. PMID 16394003 DOI: 10.4049/Jimmunol.176.2.1148  0.395
2004 Garcea RL, Gissmann L. Virus-like particles as vaccines and vessels for the delivery of small molecules. Current Opinion in Biotechnology. 15: 513-7. PMID 15560977 DOI: 10.1016/J.Copbio.2004.10.002  0.38
2004 Casini GL, Graham D, Heine D, Garcea RL, Wu DT. In vitro papillomavirus capsid assembly analyzed by light scattering. Virology. 325: 320-7. PMID 15246271 DOI: 10.1016/J.Virol.2004.04.034  0.415
2003 Carter JJ, Madeleine MM, Wipf GC, Garcea RL, Pipkin PA, Minor PD, Galloway DA. Lack of serologic evidence for prevalent simian virus 40 infection in humans. Journal of the National Cancer Institute. 95: 1522-30. PMID 14559874 DOI: 10.1093/Jnci/Djg074  0.366
2003 Chromy LR, Pipas JM, Garcea RL. Chaperone-mediated in vitro assembly of Polyomavirus capsids. Proceedings of the National Academy of Sciences of the United States of America. 100: 10477-82. PMID 12928495 DOI: 10.1073/Pnas.1832245100  0.664
2003 Garcea RL, Imperiale MJ. Simian virus 40 infection of humans. Journal of Virology. 77: 5039-45. PMID 12692206 DOI: 10.1128/Jvi.77.9.5039-5045.2003  0.409
2003 Finnen RL, Erickson KD, Chen XS, Garcea RL. Interactions between papillomavirus L1 and L2 capsid proteins. Journal of Virology. 77: 4818-26. PMID 12663788 DOI: 10.1128/Jvi.77.8.4818-4826.2003  0.304
2003 Ohlschläger P, Osen W, Dell K, Faath S, Garcea RL, Jochmus I, Müller M, Pawlita M, Schäfer K, Sehr P, Staib C, Sutter G, Gissmann L. Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice. Journal of Virology. 77: 4635-45. PMID 12663770 DOI: 10.1128/Jvi.77.8.4635-4645.2003  0.351
2002 Garcea RL. SV40: A human pathogen? Disease Markers. 17: 149-51. PMID 11790879 DOI: 10.1155/2001/515039  0.306
2001 Yuan H, Estes PA, Chen Y, Newsome J, Olcese VA, Garcea RL, Schlegel R. Immunization with a pentameric L1 fusion protein protects against papillomavirus infection. Journal of Virology. 75: 7848-53. PMID 11483728 DOI: 10.1128/Jvi.75.17.7848-7853.2001  0.417
2001 Chen XS, Casini G, Harrison SC, Garcea RL. Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1. Journal of Molecular Biology. 307: 173-82. PMID 11243812 DOI: 10.1006/Jmbi.2000.4464  0.399
2001 Szomolanyi-Tsuda E, Brien JD, Dorgan JE, Garcea RL, Woodland RT, Welsh RM. Antiviral T-cell-independent type 2 antibody responses induced in vivo in the absence of T and NK cells. Virology. 280: 160-8. PMID 11162830 DOI: 10.1006/Viro.2000.0766  0.337
2000 Chen XS, Garcea RL, Goldberg I, Casini G, Harrison SC. Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16. Molecular Cell. 5: 557-67. PMID 10882140 DOI: 10.1016/S1097-2765(00)80449-9  0.414
2000 Szomolanyi-Tsuda E, Brien JD, Dorgan JE, Welsh RM, Garcea RL. The role of CD40-CD154 interaction in antiviral T cell-independent IgG responses. Journal of Immunology (Baltimore, Md. : 1950). 164: 5877-82. PMID 10820268 DOI: 10.4049/Jimmunol.164.11.5877  0.302
2000 Schwartz R, Garcea RL, Berger B. "Local rules" theory applied to polyomavirus polymorphic capsid assemblies. Virology. 268: 461-70. PMID 10704354 DOI: 10.1006/Viro.1999.0180  0.386
1998 Szomolanyi-Tsuda E, Le QP, Garcea RL, Welsh RM. T-cell-independent immunoglobulin G responses in vivo are elicited by live-virus infection but not by immunization with viral proteins or virus- like particles Journal of Virology. 72: 6665-6670. PMID 9658113 DOI: 10.1128/Jvi.72.8.6665-6670.1998  0.415
1998 Rose RC, White WI, Li M, Suzich JA, Lane C, Garcea RL. Human papillomavirus type 11 recombinant L1 capsomeres induce virus-neutralizing antibodies. Journal of Virology. 72: 6151-4. PMID 9621080 DOI: 10.1128/Jvi.72.7.6151-6154.1998  0.324
1998 Li M, Beard P, Estes PA, Lyon MK, Garcea RL. Intercapsomeric disulfide bonds in papillomavirus assembly and disassembly. Journal of Virology. 72: 2160-7. PMID 9499072 DOI: 10.1128/Jvi.72.3.2160-2167.1998  0.46
1997 Li M, Cripe TP, Estes PA, Lyon MK, Rose RC, Garcea RL. Expression of the human papillomavirus type 11 L1 capsid protein in Escherichia coli: characterization of protein domains involved in DNA binding and capsid assembly. Journal of Virology. 71: 2988-95. PMID 9060658 DOI: 10.1128/Jvi.71.4.2988-2995.1997  0.415
1996 Delos SE, Cripe TP, Leavitt AD, Greisman H, Garcea RL. Expression of the polyomavirus minor capsid proteins VP2 and VP3 in Escherichia coli: in vitro interactions with recombinant VP1 capsomeres. Journal of Virology. 69: 7734-42. PMID 7494283 DOI: 10.1128/Jvi.69.12.7734-7742.1995  0.417
1995 Li M, Delos SE, Montross L, Garcea RL. Polyomavirus VP1 phosphorylation: coexpression with the VP2 capsid protein modulates VP1 phosphorylation in Sf9 insect cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 5992-6. PMID 7597067 DOI: 10.1073/Pnas.92.13.5992  0.445
1995 Li M, Lyon MK, Garcea RL. In vitro phosphorylation of the polyomavirus major capsid protein VP1 on serine 66 by casein kinase II. The Journal of Biological Chemistry. 270: 26006-11. PMID 7592792 DOI: 10.1074/Jbc.270.43.26006  0.382
1995 Lednicky JA, Garcea RL, Bergsagel DJ, Butel JS. Natural simian virus 40 strains are present in human choroid plexus and ependymoma tumors. Virology. 212: 710-7. PMID 7571441 DOI: 10.1006/Viro.1995.1529  0.303
1995 Cripe TP, Delos SE, Estes PA, Garcea RL. In vivo and in vitro association of hsc70 with polyomavirus capsid proteins. Journal of Virology. 69: 7807-13. PMID 7494292 DOI: 10.1128/Jvi.69.12.7807-7813.1995  0.502
1994 Li M, Garcea RL. Identification of the threonine phosphorylation sites on the polyomavirus major capsid protein VP1: relationship to the activity of middle T antigen. Journal of Virology. 68: 320-7. PMID 8254743 DOI: 10.1128/Jvi.68.1.320-327.1994  0.402
1994 Hendrix RW, Garcea RL. Capsid assembly of dsDNA viruses Seminars in Virology. 5: 15-26. DOI: 10.1006/Smvy.1994.1003  0.462
1993 Sahli R, Freund R, Dubensky T, Garcea R, Bronson R, Benjamin T. Defect in entry and altered pathogenicity of a polyoma virus mutant blocked in VP2 myristylation Virology. 192: 142-153. PMID 8390748 DOI: 10.1006/Viro.1993.1016  0.474
1993 Delos SE, Montross L, Moreland RB, Garcea RL. Expression of the polyomavirus VP2 and VP3 proteins in insect cells: coexpression with the major capsid protein VP1 alters VP2/VP3 subcellular localization. Virology. 194: 393-8. PMID 8386884 DOI: 10.1006/Viro.1993.1274  0.488
1993 Rose RC, Bonnez W, Reichman RC, Garcea RL. Expression of human papillomavirus type 11 L1 protein in insect cells: in vivo and in vitro assembly of viruslike particles. Journal of Virology. 67: 1936-44. PMID 8383219 DOI: 10.1128/Jvi.67.4.1936-1944.1993  0.432
1992 Bergsagel DJ, Finegold MJ, Butel JS, Kupsky WJ, Garcea RL. DNA sequences similar to those of simian virus 40 in ependymomas and choroid plexus tumors of childhood. The New England Journal of Medicine. 326: 988-93. PMID 1312224 DOI: 10.1056/Nejm199204093261504  0.389
1991 Moreland RB, Montross L, Garcea RL. Characterization of the DNA-binding properties of the polyomavirus capsid protein VP1. Journal of Virology. 65: 1168-76. PMID 1847446 DOI: 10.1128/Jvi.65.3.1168-1176.1991  0.361
1991 Freund R, Garcea RL, Sahli R, Benjamin TL. A single-amino-acid substitution in polyomavirus VP1 correlates with plaque size and hemagglutination behavior. Journal of Virology. 65: 350-5. PMID 1845896 DOI: 10.1128/Jvi.65.1.350-355.1991  0.307
1991 Moreland RB, Garcea RL. Characterization of a nuclear localization sequence in the polyomavirus capsid protein VP1. Virology. 185: 513-8. PMID 1656604 DOI: 10.1016/0042-6822(91)90811-O  0.351
1991 Montross L, Watkins S, Moreland RB, Mamon H, Caspar DL, Garcea RL. Nuclear assembly of polyomavirus capsids in insect cells expressing the major capsid protein VP1. Journal of Virology. 65: 4991-8. PMID 1651418 DOI: 10.1128/Jvi.65.9.4991-4998.1991  0.515
1989 Salunke DM, Caspar DL, Garcea RL. Polymorphism in the assembly of polyomavirus capsid protein VP1. Biophysical Journal. 56: 887-900. PMID 2557933 DOI: 10.1016/S0006-3495(89)82735-3  0.463
1989 Garcea RL, Talmage DA, Harmatz A, Freund R, Benjamin TL. Separation of host range from transformation functions of the hr-t gene of polyomavirus. Virology. 168: 312-9. PMID 2536985 DOI: 10.1016/0042-6822(89)90271-7  0.347
1987 Moreland RB, Langevin GL, Singer RH, Garcea RL, Hereford LM. Amino acid sequences that determine the nuclear localization of yeast histone 2B. Molecular and Cellular Biology. 7: 4048-57. PMID 3123916 DOI: 10.1128/Mcb.7.11.4048  0.348
1987 Garcea RL, Salunke DM, Caspar DL. Site-directed mutation affecting polyomavirus capsid self-assembly in vitro. Nature. 329: 86-7. PMID 3041229 DOI: 10.1038/329086A0  0.419
1987 Zullo J, Stiles CD, Garcea RL. Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins. Proceedings of the National Academy of Sciences of the United States of America. 84: 1210-4. PMID 3029770 DOI: 10.1073/Pnas.84.5.1210  0.391
1986 Salunke DM, Caspar DL, Garcea RL. Self-assembly of purified polyomavirus capsid protein VP1. Cell. 46: 895-904. PMID 3019556 DOI: 10.1016/0092-8674(86)90071-1  0.462
1986 Kaplan DR, Whitman M, Schaffhausen B, Raptis L, Garcea RL, Pallas D, Roberts TM, Cantley L. Phosphatidylinositol metabolism and polyoma-mediated transformation. Proceedings of the National Academy of Sciences of the United States of America. 83: 3624-8. PMID 2424008 DOI: 10.1073/Pnas.83.11.3624  0.36
1985 Garcea RL, Ballmer-Hofer K, Benjamin TL. Virion assembly defect of polyomavirus hr-t mutants: underphosphorylation of major capsid protein VP1 before viral DNA encapsidation. Journal of Virology. 54: 311-6. PMID 2985800 DOI: 10.1128/Jvi.54.2.311-316.1985  0.476
1983 Garcea RL, Benjamin TL. Isolation and characterization of polyoma nucleoprotein complexes. Virology. 130: 65-75. PMID 6314652 DOI: 10.1016/0042-6822(83)90118-6  0.385
1983 Garcea RL, Benjamin TL. Host range transforming gene of polyoma virus plays a role in virus assembly. Proceedings of the National Academy of Sciences of the United States of America. 80: 3613-7. PMID 6304724 DOI: 10.1073/Pnas.80.12.3613  0.471
1972 Baxter JD, Rousseau GG, Benson MC, Garcea RL, Ito J, Tomkins GM. Role of DNA and specific cytoplasmic receptors in glucocorticoid action. Proceedings of the National Academy of Sciences of the United States of America. 69: 1892-6. PMID 4403081 DOI: 10.1073/Pnas.69.7.1892  0.31
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