| Year |
Citation |
Score |
| 2023 |
Ferri DM, Nassar C, Manion KP, Kim M, Baglaenko Y, Muñoz-Grajales C, Wither JE. Elevated levels of interferon-α act directly on B cells to breach multiple tolerance mechanisms promoting autoantibody production. Arthritis & Rheumatology (Hoboken, N.J.). PMID 36807718 DOI: 10.1002/art.42482 |
0.42 |
|
| 2022 |
Gupta R, Vanlieshout E, Manion K, Bonilla D, Kim M, Muñoz-Grajales C, Nassar C, Johnson SR, Hiraki LT, Ahmad Z, Touma Z, Bookman A, Wither JE. Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies. Frontiers in Immunology. 13: 886442. PMID 35844549 DOI: 10.3389/fimmu.2022.886442 |
0.376 |
|
| 2020 |
Manion KP, Baglaenko Y, Chang NH, Talaei N, Wither JE. Impaired B cell anergy is not sufficient to breach tolerance to nuclear antigen in Vκ8/3H9 lupus-prone mice. Plos One. 15: e0236664. PMID 32722684 DOI: 10.1371/journal.pone.0236664 |
0.603 |
|
| 2019 |
Hafiz W, Nori R, Bregasi A, Noamani B, Bonilla D, Lisnevskaia L, Silverman E, Bookman AAM, Johnson SR, Landolt-Marticorena C, Wither J. Fatigue severity in anti-nuclear antibody-positive individuals does not correlate with pro-inflammatory cytokine levels or predict imminent progression to symptomatic disease. Arthritis Research & Therapy. 21: 223. PMID 31685018 DOI: 10.1186/S13075-019-2013-9 |
0.317 |
|
| 2018 |
Baglaenko Y, Chang NH, Johnson SR, Hafiz W, Manion K, Ferri D, Noamani B, Bonilla D, Rusta-Sellehy S, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C, Wither J. The presence of anti-nuclear antibodies alone is associated with changes in B cell activation and T follicular helper cells similar to those in systemic autoimmune rheumatic disease. Arthritis Research & Therapy. 20: 264. PMID 30486869 DOI: 10.1186/S13075-018-1752-3 |
0.457 |
|
| 2018 |
Chan JTH, Liu Y, Khan S, St-Germain JR, Zou C, Leung LYT, Yang J, Shi M, Grunebaum E, Campisi P, Propst EJ, Holler T, Bar-Or A, Wither JE, Cairo CW, et al. A tyrosine sulfation-dependent HLA-I modification identifies memory B cells and plasma cells. Science Advances. 4: eaar7653. PMID 30417091 DOI: 10.1126/Sciadv.Aar7653 |
0.374 |
|
| 2018 |
Shinde R, Hezaveh K, Halaby MJ, Kloetgen A, Chakravarthy A, da Silva Medina T, Deol R, Manion KP, Baglaenko Y, Eldh M, Lamorte S, Wallace D, Chodisetti SB, Ravishankar B, Liu H, ... ... Wither J, et al. Apoptotic cell-induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans. Nature Immunology. PMID 29760532 DOI: 10.1038/S41590-018-0107-1 |
0.506 |
|
| 2018 |
Wu CM, Roth TL, Baglaenko Y, Ferri DM, Brauer P, Zuniga-Pflucker JC, Rosbe KW, Wither JE, Marson A, Allen CDC. Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins. Journal of Immunological Methods. PMID 29614266 DOI: 10.1016/J.Jim.2018.03.009 |
0.348 |
|
| 2018 |
Wither J, Chang N, Johnson SR, Hafiz W, Manion K, Ferri D, Karanxha A, Noamani B, Bonilla D, Rusta-Sellehy S, Lisnevskaia L, Touma Z, Silverman E, Bookman A, Landolt-Marticorena C, et al. AI-09 T follicular helper (Tfh) cells are increased in asymptomatic anti-nuclear antibody (ANA)+ individuals and appear to play a role in epitope spreading Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.9 |
0.499 |
|
| 2017 |
Chang NH, Manion KP, Loh C, Pau E, Baglaenko Y, Wither JE. Multiple tolerance defects contribute to the breach of B cell tolerance in New Zealand Black chromosome 1 congenic mice. Plos One. 12: e0179506. PMID 28628673 DOI: 10.1371/Journal.Pone.0179506 |
0.822 |
|
| 2017 |
Baglaenko Y, Cruz Tleugabulova M, Gracey E, Talaei N, Manion KP, Chang NH, Ferri DM, Mallevaey T, Wither JE. Invariant NKT Cell Activation Is Potentiated by Homotypic trans-Ly108 Interactions. Journal of Immunology (Baltimore, Md. : 1950). PMID 28373584 DOI: 10.4049/jimmunol.1601369 |
0.37 |
|
| 2017 |
Wither J, Johnson SR, Liu T, Noamani B, Bonilla D, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C. Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis. Arthritis Research & Therapy. 19: 41. PMID 28245862 DOI: 10.1186/S13075-017-1243-Y |
0.373 |
|
| 2016 |
Baglaenko Y, Manion KP, Chang NH, Gracey E, Loh C, Wither JE. IL-10 Production Is Critical for Sustaining the Expansion of CD5+ B and NKT Cells and Restraining Autoantibody Production in Congenic Lupus-Prone Mice. Plos One. 11: e0150515. PMID 26964093 DOI: 10.1371/Journal.Pone.0150515 |
0.829 |
|
| 2016 |
Wither J, Chang N, Noamani B, Bonilla D, Johnson S, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C. AI-08 B cell phenotypic changes in anti-nuclear antibody positive individuals prior to the onset of systemic autoimmune rheumatic disease Lupus Science & Medicine. 3. DOI: 10.1136/Lupus-2016-000179.8 |
0.504 |
|
| 2016 |
Wither J, Chang N, Noamani B, Bonilla D, Johnson S, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C. THU0265 B Cell Phenotypic Changes in anti-Nuclear Antibody Positive Individuals Prior To The Onset of Systemic Autoimmune Rheumatic Disease Annals of the Rheumatic Diseases. 75: 283.3-284. DOI: 10.1136/Annrheumdis-2016-Eular.5878 |
0.533 |
|
| 2015 |
Talaei N, Yu T, Manion K, Bremner R, Wither JE. Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 26432891 DOI: 10.4049/jimmunol.1500552 |
0.34 |
|
| 2015 |
Abou El Hassan M, Huang K, Eswara MB, Zhao M, Song L, Yu T, Liu Y, Liu JC, McCurdy S, Ma A, Wither J, Jin J, Zacksenhaus E, Wrana JL, Bremner R. Cancer Cells Hijack PRC2 to Modify Multiple Cytokine Pathways. Plos One. 10: e0126466. PMID 26030458 DOI: 10.1371/Journal.Pone.0126466 |
0.306 |
|
| 2015 |
Baglaenko Y, Manion KP, Chang NH, Loh C, Lajoie G, Wither JE. Suppression of autoimmunity by CD5(+) IL-10-producing B cells in lupus-prone mice. Genes and Immunity. 16: 311-20. PMID 25973757 DOI: 10.1038/gene.2015.17 |
0.803 |
|
| 2015 |
Steiman AJ, Urowitz MB, Ibañez D, Li TT, Gladman DD, Wither J. Anti-dsDNA and Antichromatin Antibody Isotypes in Serologically Active Clinically Quiescent Systemic Lupus Erythematosus. The Journal of Rheumatology. 42: 810-6. PMID 25729033 DOI: 10.3899/Jrheum.140796 |
0.327 |
|
| 2015 |
Chang NH, Li TT, Kim JJ, Landolt-Marticorena C, Fortin PR, Gladman DD, Urowitz MB, Wither JE. Interferon-α induces altered transitional B cell signaling and function in Systemic Lupus Erythematosus. Journal of Autoimmunity. 58: 100-10. PMID 25678471 DOI: 10.1016/J.Jaut.2015.01.009 |
0.456 |
|
| 2015 |
Li T, Prokopec SD, Morrison S, Lou W, Reich H, Gladman D, Urowitz M, Scholey J, Fortin PR, Boutros PC, Wither J, Landolt-Marticorena C. Anti-nucleosome antibodies outperform traditional biomarkers as longitudinal indicators of disease activity in systemic lupus erythematosus. Rheumatology (Oxford, England). 54: 449-57. PMID 25193804 DOI: 10.1093/Rheumatology/Keu326 |
0.333 |
|
| 2015 |
Wither J, Liu T, Noamani B, Bonilla D, Johnson S, Lisnevskaia L, Silverman E, Bookman A, Landolt-Marticorena C. OP0078 Presence of an Interferon Signature in Anti-Nuclear Antibody Positive Individuals Prior to the Onset of Systemic Autoimmune Rheumatic Disease Annals of the Rheumatic Diseases. 74: 98.1-98. DOI: 10.1136/Annrheumdis-2015-Eular.5017 |
0.326 |
|
| 2015 |
Wither J, Prokopec S, Noamani B, Bonilla D, Touma Z, Reich H, Scholey J, Fortin P, Boutros P, Landolt-Marticorena C. OP0091 A Low Density Granulocyte Gene Expression Signature Distinguishes Between Active Patients with and Without Nephritis in Systemic Lupus Erythematosus (SLE) Annals of the Rheumatic Diseases. 74: 103.1-103. DOI: 10.1136/Annrheumdis-2015-Eular.4965 |
0.352 |
|
| 2015 |
Landolt-Marticorena C, Rusta-Sallehy S, Noamani B, Bonilla D, Lisnevskaia L, Johnson S, Silverman E, Bookman A, Wither J. FRI0004 A Progressive Stepwise Accrual of T Cell Abnormalities Marks the Transition from Benign to Symptomatic Autoimmunity Annals of the Rheumatic Diseases. 74: 421.1-421. DOI: 10.1136/Annrheumdis-2015-Eular.4052 |
0.406 |
|
| 2013 |
Talaei N, Cheung YH, Landolt-Marticorena C, Noamani B, Li T, Wither JE. T Cell and Dendritic Cell Abnormalities Synergize to Expand Pro-Inflammatory T Cell Subsets Leading to Fatal Autoimmunity in B6.NZBc1 Lupus-Prone Mice Plos One. 8. PMID 24073245 DOI: 10.1371/journal.pone.0075166 |
0.521 |
|
| 2013 |
Pau E, Loh C, Minty GE, Chang NH, Wither JE. Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13. Genes and Immunity. 14: 154-61. PMID 23328841 DOI: 10.1038/Gene.2012.64 |
0.816 |
|
| 2012 |
Pau E, Cheung YH, Loh C, Lajoie G, Wither JE. TLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice. Plos One. 7: e36761. PMID 22574220 DOI: 10.1371/Journal.Pone.0036761 |
0.808 |
|
| 2012 |
Talaei N, Landolt-Marticorena C, Noamani B, Pau E, Chang N, Wither J. Genetic polymorphisms leading to altered T-cell and dendritic cell function cooperate to produce expansion of proinflammatory T-cell subsets in NZB c1 congenic mice Arthritis Research & Therapy. 14: 1-28. DOI: 10.1186/Ar3962 |
0.799 |
|
| 2011 |
Loh C, Pau E, Lajoie G, Li TT, Baglaenko Y, Cheung YH, Chang NH, Wither JE. Epistatic suppression of fatal autoimmunity in New Zealand black bicongenic mice. Journal of Immunology (Baltimore, Md. : 1950). 186: 5845-53. PMID 21464090 DOI: 10.4049/Jimmunol.1003426 |
0.826 |
|
| 2011 |
Pau E, Chang NH, Loh C, Lajoie G, Wither JE. Abrogation of pathogenic IgG autoantibody production in CD40L gene-deleted lupus-prone New Zealand Black mice. Clinical Immunology (Orlando, Fla.). 139: 215-27. PMID 21414847 DOI: 10.1016/J.Clim.2011.02.005 |
0.813 |
|
| 2011 |
Cheung YH, Landolt-Marticorena C, Lajoie G, Wither JE. The lupus phenotype in B6.NZBc1 congenic mice reflects interactions between multiple susceptibility loci and a suppressor locus. Genes and Immunity. 12: 251-62. PMID 21307879 DOI: 10.1038/gene.2010.71 |
0.429 |
|
| 2011 |
Loh C, Pau E, Chang NH, Wither JE. An intrinsic B-cell defect supports autoimmunity in New Zealand black chromosome 13 congenic mice. European Journal of Immunology. 41: 527-36. PMID 21268021 DOI: 10.1002/Eji.201040983 |
0.817 |
|
| 2011 |
Reich HN, Gladman DD, Urowitz MB, Bargman JM, Hladunewich MA, Lou W, Fan SC, Su J, Herzenberg AM, Cattran DC, Wither J, Landolt-Marticorena C, Scholey JW, Fortin PR. Persistent proteinuria and dyslipidemia increase the risk of progressive chronic kidney disease in lupus erythematosus. Kidney International. 79: 914-20. PMID 21248713 DOI: 10.1038/Ki.2010.525 |
0.312 |
|
| 2011 |
Landolt-Marticorena C, Wither R, Reich H, Herzenberg A, Scholey J, Gladman DD, Urowitz MB, Fortin PR, Wither J. Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus. The Journal of Rheumatology. 38: 642-51. PMID 21239754 DOI: 10.3899/Jrheum.100214 |
0.524 |
|
| 2011 |
Budarf ML, Goyette P, Boucher G, Lian J, Graham RR, Claudio JO, Hudson T, Gladman D, Clarke AE, Pope JE, Peschken C, Smith CD, Hanly J, Rich E, Boire G, ... ... Wither J, et al. A targeted association study in systemic lupus erythematosus identifies multiple susceptibility alleles. Genes and Immunity. 12: 51-8. PMID 20962850 DOI: 10.1038/Gene.2010.47 |
0.4 |
|
| 2010 |
Chang NH, Cheung YH, Loh C, Pau E, Roy V, Cai YC, Wither J. B Cell activating factor (BAFF) and T cells cooperate to breach B cell tolerance in lupus-prone New Zealand Black (NZB) mice Plos One. 5. PMID 20661465 DOI: 10.1371/Journal.Pone.0011691 |
0.817 |
|
| 2009 |
Cheung YH, Loh C, Pau E, Kim J, Wither J. Insights into the genetic basis and immunopathogenesis of systemic lupus erythematosus from the study of mouse models Seminars in Immunology. 21: 372-382. PMID 19926489 DOI: 10.1016/J.Smim.2009.10.005 |
0.746 |
|
| 2009 |
Landolt-Marticorena C, Bonventi G, Lubovich A, Ferguson C, Unnithan T, Su J, Gladman DD, Urowitz M, Fortin PR, Wither J. Lack of association between the interferon-alpha signature and longitudinal changes in disease activity in systemic lupus erythematosus. Annals of the Rheumatic Diseases. 68: 1440-6. PMID 18772188 DOI: 10.1136/Ard.2008.093146 |
0.34 |
|
| 2009 |
Graham DC, Goyette P, Graham R, Moser K, Gaffney P, Montpetit A, Chad L, Hudson T, Altshuler D, Fortin P, Wither J, Behrens T, Rioux J, Vyse T. F.31. Lost Inhibitions? T Cell Activation Pathways in SLE Clinical Immunology. 131: S102. DOI: 10.1016/J.Clim.2009.03.297 |
0.32 |
|
| 2008 |
Wither J, Cai YC, Lim S, McKenzie T, Roslin N, Claudio JO, Cooper GS, Hudson TJ, Paterson AD, Greenwood CM, Gladman D, Pope J, Pineau CA, Smith CD, Hanly JG, et al. Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity. Arthritis Research & Therapy. 10: R108. PMID 18783591 DOI: 10.1186/Ar2505 |
0.424 |
|
| 2008 |
Cunninghame Graham DS, Vyse TJ, Fortin PR, Montpetit A, Cai YC, Lim S, McKenzie T, Farwell L, Rhodes B, Chad L, Hudson TJ, Sharpe A, Terhorst C, Greenwood CM, Wither J, et al. Association of LY9 in UK and Canadian SLE families. Genes and Immunity. 9: 93-102. PMID 18216865 DOI: 10.1038/Sj.Gene.6364453 |
0.434 |
|
| 2008 |
Chang NH, McKenzie T, Bonventi G, Landolt-Marticorena C, Fortin PR, Gladman D, Urowitz M, Wither JE. Expanded population of activated antigen-engaged cells within the naive B cell compartment of patients with systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 180: 1276-84. PMID 18178868 DOI: 10.4049/Jimmunol.180.2.1276 |
0.378 |
|
| 2007 |
Roy V, Bonventi G, Cai Y, Macleod R, Wither JE. Immune mechanisms leading to abnormal B cell selection and activation in New Zealand Black mice. European Journal of Immunology. 37: 2645-56. PMID 17668901 DOI: 10.1002/eji.200737334 |
0.55 |
|
| 2007 |
Loh C, Cai YC, Bonventi G, Lajoie G, Macleod R, Wither JE. Dissociation of the genetic loci leading to b1a and NKT cell expansions from autoantibody production and renal disease in B6 mice with an introgressed New Zealand Black chromosome 4 interval. Journal of Immunology (Baltimore, Md. : 1950). 178: 1608-17. PMID 17237410 DOI: 10.4049/Jimmunol.178.3.1608 |
0.833 |
|
| 2006 |
Levine JS, Subang R, Nasr SH, Fournier S, Lajoie G, Wither J, Rauch J. Immunization with an apoptotic cell-binding protein recapitulates the nephritis and sequential autoantibody emergence of systemic lupus erythematosus. Journal of Immunology (Baltimore, Md. : 1950). 177: 6504-16. PMID 17056583 DOI: 10.4049/Jimmunol.177.9.6504 |
0.479 |
|
| 2006 |
Baggio LL, Holland D, Wither J, Drucker DJ. Lymphocytic infiltration and immune activation in metallothionein promoter-exendin-4 (MT-Exendin) transgenic mice. Diabetes. 55: 1562-70. PMID 16731818 DOI: 10.2337/Db05-1502 |
0.526 |
|
| 2005 |
Cheung YH, Chang NH, Cai YC, Bonventi G, MacLeod R, Wither JE. Functional interplay between intrinsic B and T cell defects leads to amplification of autoimmune disease in New Zealand Black chromosome 1 congenic mice Journal of Immunology. 175: 8154-8164. PMID 16339554 |
0.616 |
|
| 2005 |
Roy V, Chang NH, Cai Y, Bonventi G, Wither J. Aberrant IgM signaling promotes survival of transitional T1 B cells and prevents tolerance induction in lupus-prone New Zealand black mice. Journal of Immunology (Baltimore, Md. : 1950). 175: 7363-71. PMID 16301643 DOI: 10.4049/Jimmunol.175.11.7363 |
0.613 |
|
| 2005 |
Wither JE, Loh C, Lajoie G, Heinrichs S, Cai YC, Bonventi G, MacLeod R. Colocalization of expansion of the splenic marginal zone population with abnormal B cell activation and autoantibody production in B6 mice with an introgressed New Zealand Black chromosome 13 interval. Journal of Immunology (Baltimore, Md. : 1950). 175: 4309-19. PMID 16177071 DOI: 10.4049/Jimmunol.175.7.4309 |
0.856 |
|
| 2004 |
Chang NH, MacLeod R, Wither JE. Autoreactive B cells in lupus-prone New Zealand black mice exhibit aberrant survival and proliferation in the presence of self-antigen in vivo. Journal of Immunology (Baltimore, Md. : 1950). 172: 1553-60. PMID 14734734 |
0.607 |
|
| 2003 |
Wither JE, Lajoie G, Heinrichs S, Cai YC, Chang N, Ciofani A, Cheung YH, MacLeod R. Functional dissection of lupus susceptibility loci on the New Zealand black mouse chromosome 1: evidence for independent genetic loci affecting T and B cell activation. Journal of Immunology (Baltimore, Md. : 1950). 171: 1697-706. PMID 12902468 |
0.637 |
|
| 2000 |
Wither J, Vukusic B. T-cell tolerance induction is normal in the (NZB x NZW)F1 murine model of systemic lupus erythematosus. Immunology. 99: 345-51. PMID 10712663 DOI: 10.1046/j.1365-2567.2000.00981.x |
0.468 |
|
| 2000 |
Wither JE, Paterson AD, Vukusic B. Genetic dissection of B cell traits in New Zealand black mice. The expanded population of B cells expressing up-regulated costimulatory molecules shows linkage to Nba2. European Journal of Immunology. 30: 356-65. PMID 10671190 DOI: 10.1002/1521-4141(200002)30:2<356::AID-IMMU356>3.0.CO;2-H |
0.602 |
|
| 2000 |
Wither JE, Roy V, Brennan LA. Activated B cells express increased levels of costimulatory molecules in young autoimmune NZB and (NZB x NZW)F(1) mice. Clinical Immunology (Orlando, Fla.). 94: 51-63. PMID 10607490 DOI: 10.1006/clim.1999.4806 |
0.543 |
|
| 1998 |
Wu Y, Nadler MJ, Brennan LA, Gish GD, Timms JF, Fusaki N, Jongstra-Bilen J, Tada N, Pawson T, Wither J, Neel BG, Hozumi N. The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. Current Biology : Cb. 8: 1009-17. PMID 9740800 DOI: 10.1016/S0960-9822(07)00421-6 |
0.523 |
|
| 1996 |
Poplonski L, Vukusic B, Pawling J, Clapoff S, Roder J, Hozumi N, Wither J. Tolerance is overcome in beef insulin-transgenic mice by activation of low-affinity autoreactive T cells. European Journal of Immunology. 26: 601-9. PMID 8605927 DOI: 10.1002/Eji.1830260315 |
0.516 |
|
| 1995 |
Vukusic B, Poplonski L, Phillips L, Pawling J, Delovitch T, Hozumi N, Wither J. Both MHC and background gene heterozygosity alter T cell receptor repertoire selection in an antigen-specific response. Molecular Immunology. 32: 1355-67. PMID 8643105 DOI: 10.1016/0161-5890(95)00111-5 |
0.488 |
|
| 1990 |
Kang J, Wither J, Hozumi N. Long-term expression of a T-cell receptor beta-chain gene in mice reconstituted with retrovirus-infected hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 9803-7. PMID 2175916 DOI: 10.1073/Pnas.87.24.9803 |
0.392 |
|
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