Year |
Citation |
Score |
2020 |
Xing H, Andrud KW, Soti F, Rouchaud A, Jahn SC, Lu Z, Cho YH, Habibi S, Corsino P, Slavov S, Rocca JR, Lindstrom JS, Lukas RJ, Kem W. A Methyl Scan of the Pyrrolidinium Ring of Nicotine Reveals Significant Differences in its Interactions with α7 and α4β2 Nicotinic Acetylcholine Receptors. Molecular Pharmacology. PMID 32474444 DOI: 10.1124/Mol.119.118786 |
0.356 |
|
2020 |
Xing H, Keshwah S, Rouchaud A, Kem WR. A Pharmacological Comparison of Two Isomeric Nicotinic Receptor Agonists: The Marine Toxin Isoanatabine and the Tobacco Alkaloid Anatabine. Marine Drugs. 18. PMID 32053997 DOI: 10.3390/Md18020106 |
0.351 |
|
2019 |
Andrud K, Xing H, Gabrielsen B, Bloom L, Mahnir V, Lee S, Green BT, Lindstrom J, Kem W. Investigation of the Possible Pharmacologically Active Forms of the Nicotinic Acetylcholine Receptor Agonist Anabaseine. Marine Drugs. 17. PMID 31671780 DOI: 10.3390/Md17110614 |
0.403 |
|
2016 |
Olincy A, Blakeley-Smith A, Johnson L, Kem WR, Freedman R. Brief Report: Initial Trial of Alpha7-Nicotinic Receptor Stimulation in Two Adult Patients with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. PMID 27565651 DOI: 10.1007/S10803-016-2890-6 |
0.325 |
|
2016 |
Green BT, Lee ST, Welch KD, Cook D, Kem WR. Activation and Desensitization of Peripheral Muscle and Neuronal Nicotinic Acetylcholine Receptors by Selected, Naturally-Occurring Pyridine Alkaloids. Toxins. 8. PMID 27384586 DOI: 10.3390/Toxins8070204 |
0.352 |
|
2015 |
Butala M, Šega D, Tomc B, Podlesek Z, Kem WR, Küpper FC, Turk T. Recombinant expression and predicted structure of parborlysin, a cytolytic protein from the Antarctic heteronemertine Parborlasia corrugatus. Toxicon : Official Journal of the International Society On Toxinology. 108: 32-7. PMID 26435341 DOI: 10.1016/J.Toxicon.2015.09.044 |
0.316 |
|
2013 |
Isaacson MD, Horenstein NA, Stokes C, Kem WR, Papke RL. Point-to-point ligand-receptor interactions across the subunit interface modulate the induction and stabilization of conformational states of alpha7 nAChR by benzylidene anabaseines. Biochemical Pharmacology. 85: 817-28. PMID 23352650 DOI: 10.1016/J.Bcp.2013.01.010 |
0.391 |
|
2013 |
Suzuki S, Kawamata J, Matsushita T, Matsumura A, Hisahara S, Takata K, Kitamura Y, Kem W, Shimohama S. 3-[(2,4-Dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats. Journal of Neuroscience Research. 91: 462-71. PMID 23239187 DOI: 10.1002/Jnr.23160 |
0.303 |
|
2012 |
Kem WR, Junoy J. 63. Discovery of the Nicotinic Receptor Toxin Anabaseine in a Polystyliferan Nemertine Toxicon. 60: 125-126. DOI: 10.1016/J.Toxicon.2012.04.064 |
0.334 |
|
2011 |
Kalappa BI, Feng L, Kem WR, Gusev AG, Uteshev VV. Mechanisms of facilitation of synaptic glutamate release by nicotinic agonists in the nucleus of the solitary tract. American Journal of Physiology. Cell Physiology. 301: C347-61. PMID 21613611 DOI: 10.1152/Ajpcell.00473.2010 |
0.317 |
|
2010 |
Shen H, Kihara T, Hongo H, Wu X, Kem WR, Shimohama S, Akaike A, Niidome T, Sugimoto H. Neuroprotection by donepezil against glutamate excitotoxicity involves stimulation of alpha7 nicotinic receptors and internalization of NMDA receptors. British Journal of Pharmacology. 161: 127-39. PMID 20718745 DOI: 10.1111/J.1476-5381.2010.00894.X |
0.306 |
|
2010 |
Stevens KE, Cornejo B, Adams CE, Zheng L, Yonchek J, Hoffman KL, Christians U, Kem WR. Continuous administration of a selective alpha7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice. Brain Research. 1352: 140-6. PMID 20599427 DOI: 10.1016/J.Brainres.2010.06.063 |
0.363 |
|
2010 |
Razpotnik A, Krizaj I, Sribar J, Kordis D, Macek P, Frangez R, Kem WR, Turk T. A new phospholipase A2 isolated from the sea anemone Urticina crassicornis - its primary structure and phylogenetic classification. The Febs Journal. 277: 2641-53. PMID 20553498 DOI: 10.1111/J.1742-464X.2010.07674.X |
0.306 |
|
2010 |
Slavov SH, Radzvilovits M, LeFrancois S, Stoyanova-Slavova IB, Soti F, Kem WR, Katritzky AR. A computational study of the binding of 3-(arylidene) anabaseines to two major brain nicotinic acetylcholine receptors and to the acetylcholine binding protein. European Journal of Medicinal Chemistry. 45: 2433-46. PMID 20236734 DOI: 10.1016/J.Ejmech.2010.02.027 |
0.384 |
|
2010 |
Green BT, Lee ST, Panter KE, Welch KD, Cook D, Pfister JA, Kem WR. Actions of piperidine alkaloid teratogens at fetal nicotinic acetylcholine receptors. Neurotoxicology and Teratology. 32: 383-90. PMID 20116429 DOI: 10.1016/J.Ntt.2010.01.011 |
0.313 |
|
2010 |
Tregellas JR, Olincy A, Johnson L, Tanabe J, Shatti S, Martin LF, Singel D, Du YP, Soti F, Kem WR, Freedman R. Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 938-42. PMID 19956085 DOI: 10.1038/Npp.2009.196 |
0.302 |
|
2009 |
López-Hernández GY, Thinschmidt JS, Morain P, Trocme-Thibierge C, Kem WR, Soti F, Papke RL. Positive modulation of alpha7 nAChR responses in rat hippocampal interneurons to full agonists and the alpha7-selective partial agonists, 4OH-GTS-21 and S 24795. Neuropharmacology. 56: 821-30. PMID 19705574 DOI: 10.1016/J.Neuropharm.2009.01.011 |
0.34 |
|
2009 |
Hibbs RE, Sulzenbacher G, Shi J, Talley TT, Conrod S, Kem WR, Taylor P, Marchot P, Bourne Y. Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal alpha7 nicotinic acetylcholine receptor. The Embo Journal. 28: 3040-51. PMID 19696737 DOI: 10.1038/Emboj.2009.227 |
0.394 |
|
2009 |
Turk T, Kem WR. The phylum Cnidaria and investigations of its toxins and venoms until 1990 Toxicon. 54: 1031-1037. PMID 19576920 DOI: 10.1016/J.Toxicon.2009.06.031 |
0.312 |
|
2009 |
Arias HR, Xing H, Macdougall K, Blanton MP, Soti F, Kem WR. Interaction of benzylidene-anabaseine analogues with agonist and allosteric sites on muscle nicotinic acetylcholine receptors. British Journal of Pharmacology. 157: 320-30. PMID 19338581 DOI: 10.1111/J.1476-5381.2009.00156.X |
0.389 |
|
2009 |
Razpotnik A, Križaj I, Kem WR, Maček P, Turk T. A new cytolytic protein from the sea anemone Urticina crassicornis that binds to cholesterol- and sphingomyelin-rich membranes Toxicon. 53: 762-769. PMID 19232528 DOI: 10.1016/J.Toxicon.2009.02.007 |
0.331 |
|
2009 |
Papke RL, Kem WR, Soti F, López-Hernández GY, Horenstein NA. Activation and desensitization of nicotinic alpha7-type acetylcholine receptors by benzylidene anabaseines and nicotine. The Journal of Pharmacology and Experimental Therapeutics. 329: 791-807. PMID 19223664 DOI: 10.1124/Jpet.108.150151 |
0.426 |
|
2009 |
Xing H, Rouchaud A, Keshwah S, Kem W. Isoanatabine, a naturally occurring α4β2 nicotinic receptor agonist Biochemical Pharmacology. 78: 906-907. DOI: 10.1016/J.Bcp.2009.06.047 |
0.329 |
|
2008 |
Rowland NE, Robertson K, Soti F, Kem WR. Nicotine analog inhibition of nicotine self-administration in rats. Psychopharmacology. 199: 605-13. PMID 18536909 DOI: 10.1007/S00213-008-1186-8 |
0.33 |
|
2008 |
Freedman R, Olincy A, Buchanan RW, Harris JG, Gold JM, Johnson L, Allensworth D, Guzman-Bonilla A, Clement B, Ball MP, Kutnick J, Pender V, Martin LF, Stevens KE, Wagner BD, ... Kem WR, et al. Initial phase 2 trial of a nicotinic agonist in schizophrenia. The American Journal of Psychiatry. 165: 1040-7. PMID 18381905 DOI: 10.1176/Appi.Ajp.2008.07071135 |
0.317 |
|
2006 |
Talley TT, Yalda S, Ho KY, Tor Y, Soti FS, Kem WR, Taylor P. Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions. Biochemistry. 45: 8894-902. PMID 16846232 DOI: 10.1021/Bi060534Y |
0.348 |
|
2006 |
Olincy A, Harris JG, Johnson LL, Pender V, Kongs S, Allensworth D, Ellis J, Zerbe GO, Leonard S, Stevens KE, Stevens JO, Martin L, Adler LE, Soti F, Kem WR, et al. Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Archives of General Psychiatry. 63: 630-8. PMID 16754836 DOI: 10.1001/Archpsyc.63.6.630 |
0.302 |
|
2006 |
Zhang R, White NA, Soti FS, Kem WR, Machu TK. N-terminal domains in mouse and human 5-hydroxytryptamine3A receptors confer partial agonist and antagonist properties to benzylidene analogs of anabaseine. The Journal of Pharmacology and Experimental Therapeutics. 317: 1276-84. PMID 16551836 DOI: 10.1124/Jpet.106.101485 |
0.33 |
|
2006 |
Lee ST, Wildeboer K, Panter KE, Kem WR, Gardner DR, Molyneux RJ, Chang CW, Soti F, Pfister JA. Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine. Neurotoxicology and Teratology. 28: 220-8. PMID 16488116 DOI: 10.1016/J.Ntt.2005.12.010 |
0.314 |
|
2006 |
Kem W, Soti F, Wildeboer K, LeFrancois S, MacDougall K, Wei DQ, Chou KC, Arias HR. The nemertine toxin anabaseine and its derivative DMXBA (GTS-21): Chemical and pharmacological properties Marine Drugs. 4: 255-273. DOI: 10.3390/Md403255 |
0.37 |
|
2004 |
Stokes C, Papke JK, Horenstein NA, Kem WR, McCormack TJ, Papke RL. The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors. Molecular Pharmacology. 66: 14-24. PMID 15213292 DOI: 10.1124/Mol.66.1.14 |
0.341 |
|
2004 |
Martin LF, Kem WR, Freedman R. Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia Psychopharmacology. 174: 54-64. PMID 15205879 DOI: 10.1007/S00213-003-1750-1 |
0.344 |
|
2004 |
Kem WR, Mahnir VM, Prokai L, Papke RL, Cao X, LeFrancois S, Wildeboer K, Prokai-Tatrai K, Porter-Papke J, Soti F. Hydroxy metabolites of the Alzheimer's drug candidate 3-[(2,4-dimethoxy)benzylidene]-anabaseine dihydrochloride (GTS-21): their molecular properties, interactions with brain nicotinic receptors, and brain penetration. Molecular Pharmacology. 65: 56-67. PMID 14722237 DOI: 10.1124/Mol.65.1.56 |
0.362 |
|
2003 |
Kem WR, Soti F, Rittschof D. Inhibition of barnacle larval settlement and crustacean toxicity of some hoplonemertine pyridyl alkaloids. Biomolecular Engineering. 20: 355-61. PMID 12919820 DOI: 10.1016/S1389-0344(03)00049-2 |
0.35 |
|
2003 |
Arias HR, Kem WR, Trudell JR, Blanton MP. Unique general anesthetic binding sites within distinct conformational states of the nicotinic acetylcholine receptor. International Review of Neurobiology. 54: 1-50. PMID 12785284 DOI: 10.1016/S0074-7742(03)54002-8 |
0.363 |
|
2003 |
O'Neill HC, Rieger K, Kem WR, Stevens KE. DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats. Psychopharmacology. 169: 332-9. PMID 12759805 DOI: 10.1007/S00213-003-1482-2 |
0.353 |
|
2003 |
Berne S, Sepcić K, Krizaj I, Kem WR, McClintock JB, Turk T. Isolation and characterisation of a cytolytic protein from mucus secretions of the Antarctic heteronemertine Parborlasia corrugatus. Toxicon : Official Journal of the International Society On Toxinology. 41: 483-91. PMID 12657318 DOI: 10.1016/S0041-0101(02)00386-0 |
0.324 |
|
2001 |
Simosky JK, Stevens KE, Kem WR, Freedman R. Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice. Biological Psychiatry. 50: 493-500. PMID 11600102 DOI: 10.1016/S0006-3223(01)01093-9 |
0.313 |
|
2001 |
Kem WR, Soti F. Amphiporus alkaloid multiplicity implies functional diversity: Initial studies on crustacean pyridyl receptors Hydrobiologia. 456: 221-231. DOI: 10.1023/A:1013063726807 |
0.394 |
|
2000 |
Adams CE, Stevens KE, Kem WR, Freedman R. Inhibition of nitric oxide synthase prevents alpha 7 nicotinic receptor-mediated restoration of inhibitory auditory gating in rat hippocampus. Brain Research. 877: 235-44. PMID 10986337 DOI: 10.1016/S0006-8993(00)02677-9 |
0.346 |
|
2000 |
Kem WR. The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21). Behavioural Brain Research. 113: 169-81. PMID 10942043 DOI: 10.1016/S0166-4328(00)00211-4 |
0.381 |
|
1999 |
Stevens KE, Kem WR, Freedman R. Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice. Biological Psychiatry. 46: 1443-50. PMID 10578459 DOI: 10.1016/S0006-3223(99)00200-0 |
0.303 |
|
1999 |
Pennington MW, Lanigan MD, Kalman K, Mahnir VM, Rauer H, McVaugh CT, Behm D, Donaldson D, Chandy KG, Kem WR, Norton RS. Role of disulfide bonds in the structure and potassium channel blocking activity of ShK toxin. Biochemistry. 38: 14549-58. PMID 10545177 DOI: 10.1021/Bi991282M |
0.683 |
|
1999 |
van Haaren F, Anderson KG, Haworth SC, Kem WR. GTS-21, a mixed nicotinic receptor agonist/antagonist, does not affect the nicotine cue. Pharmacology, Biochemistry, and Behavior. 64: 439-44. PMID 10515327 DOI: 10.1016/S0091-3057(99)00054-4 |
0.343 |
|
1999 |
Kem WR, Pennington MW, Norton RS. Sea anemone toxins as templates for the design of immunosuppressant drugs Perspectives in Drug Discovery and Design. 15: 111-129. DOI: 10.1023/A:1017071131670 |
0.684 |
|
1998 |
Kalman K, Pennington MW, Lanigan MD, Nguyen A, Rauer H, Mahnir V, Paschetto K, Kem WR, Grissmer S, Gutman GA, Christian EP, Cahalan MD, Norton RS, Chandy KG. ShK-Dap22, a potent Kv1.3-specific immunosuppressive polypeptide. The Journal of Biological Chemistry. 273: 32697-707. PMID 9830012 DOI: 10.1074/Jbc.273.49.32697 |
0.657 |
|
1998 |
Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology. 136: 320-7. PMID 9600576 DOI: 10.1007/S002130050573 |
0.361 |
|
1997 |
Kem WR. Alzheimer's drug design based upon an invertebrate toxin (anabaseine) which is a potent nicotinic receptor agonist. Invertebrate Neuroscience : In. 3: 251-9. PMID 9783447 DOI: 10.1007/Bf02480382 |
0.364 |
|
1997 |
Summers KL, Kem WR, Giacobini E. Nicotinic agonist modulation of neurotransmitter levels in the rat frontoparietal cortex. Japanese Journal of Pharmacology. 74: 139-46. PMID 9243321 DOI: 10.1254/Jjp.74.139 |
0.338 |
|
1997 |
Barnham KJ, Dyke TR, Kem WR, Norton RS. Structure of neurotoxin B-IV from the marine worm Cerebratulus lacteus: a helical hairpin cross-linked by disulphide bonding. Journal of Molecular Biology. 268: 886-902. PMID 9180379 DOI: 10.1006/Jmbi.1997.0980 |
0.345 |
|
1996 |
Pennington MW, Mahnir VM, Khaytin I, Zaydenberg I, Byrnes ME, Kem WR. An essential binding surface for ShK toxin interaction with rat brain potassium channels. Biochemistry. 35: 16407-11. PMID 8987971 DOI: 10.1021/bi962463g |
0.632 |
|
1996 |
Pennington MW, Mahnir VM, Krafte DS, Zaydenberg I, Byrnes ME, Khaytin I, Crowley K, Kem WR. Identification of three separate binding sites on SHK toxin, a potent inhibitor of voltage-dependent potassium channels in human T-lymphocytes and rat brain. Biochemical and Biophysical Research Communications. 219: 696-701. PMID 8645244 DOI: 10.1006/Bbrc.1996.0297 |
0.644 |
|
1996 |
Dyke TR, Duggan BM, Pennington MW, Byrnes ME, Kem WR, Norton RS. Synthesis and structural characterisation of analogues of the potassium channel blocker charybdotoxin. Biochimica Et Biophysica Acta. 1292: 31-8. PMID 8547346 DOI: 10.1016/0167-4838(95)00182-4 |
0.662 |
|
1996 |
Kem W, Pennington M, Mahnir V, Byrnes M, Zaydenberg I, Khaytin I, Krafte D, Hill R, de Chastonay J. Identification of essential residues in the potassium channel inhibitor ShK toxin: analysis of monosubstituted analogs Toxicon. 34: 300. DOI: 10.1016/0041-0101(96)80899-3 |
0.629 |
|
1996 |
Kem WR, Sanyal G, Williams RW, Pennington MW. Secondary structure of ShK toxin, a potassium-channel-blocking peptide Letters in Peptide Science. 3: 69-72. DOI: 10.1007/Bf00126735 |
0.644 |
|
1996 |
Bjugstad KB, Mahnir VM, Kem WR, Socci DJ, Arendash GW. Long-term treatment with GTS-21 or nicotine enhances water maze performance in aged rats without affecting the density of nicotinic receptor subtypes in neocortex Drug Development Research. 39: 19-28. DOI: 10.1002/(Sici)1098-2299(19960901)39:1<19::Aid-Ddr3>3.0.Co;2-N |
0.339 |
|
1995 |
Kem W, Mahnir V, Pennington M. Type 2 sea anemone toxins compete with type 1 sea anemone and scorpion alpha-toxins for binding to nerve sodium channels Toxicon. 33: 268-269. DOI: 10.1016/0041-0101(95)99265-5 |
0.621 |
|
1994 |
Kem WR. Structure and membrane actions of a marine worm protein cytolysin, Cerebratulus toxin A-III. Toxicology. 87: 189-203. PMID 8160185 DOI: 10.1016/0300-483X(94)90251-8 |
0.388 |
|
1994 |
Pennington MW, Zadenberg I, Byrnes ME, Norton RS, Kem WR. Synthesis of the cardiac inotropic polypeptide anthopleurin-A. International Journal of Peptide and Protein Research. 43: 463-70. PMID 8070970 DOI: 10.1111/J.1399-3011.1994.Tb00545.X |
0.648 |
|
1994 |
Woodruff-Pak DS, Li YT, Kem WR. A nicotinic agonist (GTS-21), eyeblink classical conditioning, and nicotinic receptor binding in rabbit brain. Brain Research. 645: 309-17. PMID 8062092 DOI: 10.1016/0006-8993(94)91665-9 |
0.316 |
|
1994 |
Hunter BE, de Fiebre CM, Papke RL, Kem WR, Meyer EM. A novel nicotinic agonist facilitates induction of long-term potentiation in the rat hippocampus. Neuroscience Letters. 168: 130-4. PMID 8028765 DOI: 10.1016/0304-3940(94)90433-2 |
0.361 |
|
1994 |
Woodruff-Pak DS, Li YT, Kazmi A, Kem WR. Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits. Behavioral Neuroscience. 108: 486-93. PMID 7917042 DOI: 10.1037//0735-7044.108.3.486 |
0.317 |
|
1994 |
Monks SA, Gould AR, Lumley PE, Alewood PF, Kem WR, Goss NH, Norton RS. Limited proteolysis study of structure-function relationships in Sh I, a polypeptide neurotoxin from a sea anemone. Biochimica Et Biophysica Acta. 1207: 93-101. PMID 7913833 DOI: 10.1016/0167-4838(94)90056-6 |
0.38 |
|
1992 |
Pennington MW, Festin SM, Maccecchini ML, Kem WR. Synthesis and characterization of a disulfide bond isomer of omega-conotoxin GVIA. Toxicon : Official Journal of the International Society On Toxinology. 30: 755-64. PMID 1509493 DOI: 10.1016/0041-0101(92)90009-T |
0.6 |
|
1992 |
Salgado VL, Kem WR. Actions of three structurally distinct sea anemone toxins on crustacean and insect sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 30: 1365-81. PMID 1336629 DOI: 10.1016/0041-0101(92)90512-4 |
0.356 |
|
1992 |
Hansen PE, Kem WR, Bieber AL, Norton RS. 1H-NMR study of neurotoxin B-IV from the marine worm Cerebratulus lacteus. Solution properties, sequence-specific resonance assignments, secondary structure and global fold. European Journal of Biochemistry / Febs. 210: 231-40. PMID 1332861 DOI: 10.1111/J.1432-1033.1992.Tb17413.X |
0.341 |
|
1990 |
Kem WR, Tu CK, Williams RW, Toumadje A, Johnson WC. Circular dichroism and laser Raman spectroscopic analysis of the secondary structure of Cerebratulus lacteus toxin B-IV Journal of Protein Chemistry. 9: 433-443. PMID 2275754 DOI: 10.1007/Bf01024619 |
0.31 |
|
1990 |
Pennington MW, Kem WR, Dunn BM. Synthesis and biological activity of six monosubstituted analogs of a sea anemone polypeptide neurotoxin Peptide Research. 3: 228-232. PMID 2134066 |
0.688 |
|
1990 |
Pennington MW, Kem WR, Norton RS, Dunn BM. Chemical synthesis of a neurotoxic polypeptide from the sea anemone Stichodactyla helianthus International Journal of Peptide and Protein Research. 36: 335-343. PMID 1981881 DOI: 10.1111/J.1399-3011.1990.Tb01291.X |
0.689 |
|
1990 |
Hellberg S, Kem WR. Quantitative structure-activity relationships for sea anemone polypeptide toxins. International Journal of Peptide and Protein Research. 36: 440-4. PMID 1980491 DOI: 10.1111/J.1399-3011.1990.Tb01303.X |
0.386 |
|
1990 |
Fogh RH, Kem WR, Norton RS. Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study. The Journal of Biological Chemistry. 265: 13016-28. PMID 1973932 DOI: 10.2210/Pdb2Sh1/Pdb |
0.318 |
|
1989 |
Doyle JW, Kem WR. Binding of a radiolabeled sea anemone cytolysin to erythrocyte membranes. Biochimica Et Biophysica Acta. 987: 181-6. PMID 2574996 DOI: 10.1016/0005-2736(89)90542-7 |
0.338 |
|
1989 |
Kem WR, Parten B, Pennington MW, Price DA, Dunn BM. Isolation, characterization, and amino acid sequence of a polypeptide neurotoxin occurring in the sea anemone Stichodactyla helianthus Biochemistry. 28: 3483-3489. PMID 2568126 DOI: 10.1021/Bi00434A050 |
0.69 |
|
1989 |
Fogh RH, Mabbutt BC, Kem WR, Norton RS. Sequence-specific 1H NMR assignments and secondary structure in the sea anemone polypeptide Stichodactyla helianthus neurotoxin I. Biochemistry. 28: 1826-34. PMID 2566324 DOI: 10.1021/Bi00430A060 |
0.321 |
|
1988 |
Kem WR, Dunn BM. Separation and characterization of four different amino acid sequence variants of a sea anemone (Stichodactyla helianthus) protein cytolysin Toxicon. 26: 997-1008. PMID 2907688 DOI: 10.1016/0041-0101(88)90198-5 |
0.547 |
|
1985 |
Kem WR. Structure and action of nemertine toxins Integrative and Comparative Biology. 25: 99-111. DOI: 10.1093/Icb/25.1.99 |
0.333 |
|
1980 |
Blumenthal KM, Kem WR. Structure and action of heteronemertine polypeptide toxins: inactivation of Cerebratulus lacteus toxin B-IV by tyrosine nitration. Archives of Biochemistry and Biophysics. 203: 816-21. PMID 7458356 DOI: 10.1016/0003-9861(80)90243-X |
0.38 |
|
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