Randall Bateman - Publications

Affiliations: 
Neurology Washington University School of Medicine, St. Louis, MO, United States 

327 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Millar PR, Gordon BA, Wisch JK, Schultz SA, Benzinger TL, Cruchaga C, Hassenstab JJ, Ibanez L, Karch C, Llibre-Guerra JJ, Morris JC, Perrin RJ, Supnet-Bell C, Xiong C, Allegri RF, ... ... Bateman RJ, et al. Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease. Molecular Neurodegeneration. 18: 98. PMID 38111006 DOI: 10.1186/s13024-023-00688-3  0.351
2023 Bateman RJ, Smith J, Donohue MC, Delmar P, Abbas R, Salloway S, Wojtowicz J, Blennow K, Bittner T, Black SE, Klein G, Boada M, Grimmer T, Tamaoka A, Perry RJ, et al. Two Phase 3 Trials of Gantenerumab in Early Alzheimer's Disease. The New England Journal of Medicine. 389: 1862-1876. PMID 37966285 DOI: 10.1056/NEJMoa2304430  0.429
2023 Llibre-Guerra JJ, Iaccarino L, Coble D, Edwards L, Li Y, McDade E, Strom A, Gordon B, Mundada N, Schindler SE, Tsoy E, Ma Y, Lu R, Fagan AM, Benzinger TLS, ... ... Bateman R, et al. Longitudinal clinical, cognitive and biomarker profiles in dominantly inherited versus sporadic early-onset Alzheimer's disease. Brain Communications. 5: fcad280. PMID 37942088 DOI: 10.1093/braincomms/fcad280  0.746
2023 Rahmani F, Brier MR, Gordon BA, McKay N, Flores S, Keefe S, Hornbeck R, Ances B, Joseph-Mathurin N, Xiong C, Wang G, Raji CA, Libre-Guerra JJ, Perrin RJ, McDade E, ... ... Bateman RJ, et al. T1 and FLAIR signal intensities are related to tau pathology in dominantly inherited Alzheimer disease. Human Brain Mapping. PMID 37867465 DOI: 10.1002/hbm.26514  0.711
2023 Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, ... ... Bateman RJ, et al. Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. Jama Neurology. PMID 37843849 DOI: 10.1001/jamaneurol.2023.3618  0.738
2023 Wagemann O, Li Y, Hassenstab J, Aschenbrenner AJ, McKay NS, Gordon BA, Benzinger TLS, Xiong C, Cruchaga C, Renton AE, Perrin RJ, Berman SB, Chhatwal JP, Farlow MR, Day GS, ... ... Bateman RJ, et al. Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37740921 DOI: 10.1002/alz.13460  0.735
2023 Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, ... ... Bateman RJ, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature Medicine. PMID 37550416 DOI: 10.1038/s41591-023-02476-4  0.776
2023 Salvadó G, Horie K, Barthélemy NR, Vogel JW, Binette AP, Chen CD, Aschenbrenner AJ, Gordon BA, Benzinger TLS, Holtzman DM, Morris JC, Palmqvist S, Stomrud E, Janelidze S, Ossenkoppele R, ... ... Bateman RJ, et al. Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37503281 DOI: 10.1101/2023.07.14.23292650  0.71
2023 Horie K, Salvadó G, Barthélemy NR, Janelidze S, Li Y, He Y, Saef B, Chen CD, Jiang H, Strandberg O, Pichet Binette A, Palmqvist S, Sato C, Sachdev P, Koyama A, ... ... Bateman RJ, et al. CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer's disease. Nature Medicine. PMID 37443334 DOI: 10.1038/s41591-023-02443-z  0.761
2023 McKay NS, Gordon BA, Hornbeck RC, Dincer A, Flores S, Keefe SJ, Joseph-Mathurin N, Jack CR, Koeppe R, Millar PR, Ances BM, Chen CD, Daniels A, Hobbs DA, Jackson K, ... ... Bateman RJ, et al. Positron emission tomography and magnetic resonance imaging methods and datasets within the Dominantly Inherited Alzheimer Network (DIAN). Nature Neuroscience. PMID 37429916 DOI: 10.1038/s41593-023-01359-8  0.728
2023 Sung YJ, Yang C, Norton J, Johnson M, Fagan A, Bateman RJ, Perrin RJ, Morris JC, Farlow MR, Chhatwal JP, Schofield PR, Chui H, Wang F, Novotny B, Eteleeb A, et al. Proteomics of brain, CSF, and plasma identifies molecular signatures for distinguishing sporadic and genetic Alzheimer's disease. Science Translational Medicine. 15: eabq5923. PMID 37406134 DOI: 10.1126/scitranslmed.abq5923  0.681
2023 Lucey BP, Bateman RJ. Reply to Suvorexant for Preventing Alzheimer's Disease. Annals of Neurology. PMID 37381577 DOI: 10.1002/ana.26728  0.4
2023 Sun Z, Kwon JS, Ren Y, Chen S, Cates K, Lu X, Walker CK, Karahan H, Sviben S, Fitzpatrick JAJ, Valdez C, Houlden H, Karch CM, Bateman RJ, Sato C, et al. Endogenous recapitulation of Alzheimer's disease neuropathology through human 3D direct neuronal reprogramming. Biorxiv : the Preprint Server For Biology. PMID 37292658 DOI: 10.1101/2023.05.24.542155  0.749
2023 Schultz SA, Shirzadi Z, Schultz AP, Liu L, Fitzpatrick CD, McDade E, Barthelemy NR, Renton A, Esposito B, Joseph-Mathurin N, Cruchaga C, Chen CD, Goate A, Allegri RF, Benzinger TLS, ... ... Bateman RJ, et al. Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease. Aging Cell. e13871. PMID 37291760 DOI: 10.1111/acel.13871  0.733
2023 O'Connor A, Cash DM, Poole T, Markiewicz PJ, Fraser MR, Malone IB, Jiao J, Weston PSJ, Flores S, Hornbeck R, McDade E, Schöll M, Gordon BA, Bateman RJ, Benzinger TLS, et al. Tau accumulation in autosomal dominant Alzheimer's disease: a longitudinal [F]flortaucipir study. Alzheimer's Research & Therapy. 15: 99. PMID 37231491 DOI: 10.1186/s13195-023-01234-5  0.605
2023 Li M, Li Y, Schindler SE, Yen D, Sutcliffe S, Babulal GM, Benzinger TLS, Lenze EJ, Bateman RJ. Design and feasibility of an Alzheimer's disease blood test study in a diverse community-based population. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37204806 DOI: 10.1002/alz.13125  0.329
2023 Luo J, Ma Y, Agboola FJ, Grant E, Morris JC, McDade E, Fagan AM, Benzinger TLS, Hassenstab J, Bateman RJ, Perrin RJ, Gordon BA, Goyal M, Strain JF, Yakushev I, et al. Longitudinal Relationships of White Matter Hyperintensities and Alzheimer Disease Biomarkers Across the Adult Lifespan. Neurology. PMID 37202169 DOI: 10.1212/WNL.0000000000207378  0.76
2023 Schindler SE, Bateman RJ. Combining blood-based biomarkers to predict risk for Alzheimer's disease dementia. Nature Aging. 1: 26-28. PMID 37117995 DOI: 10.1038/s43587-020-00008-0  0.345
2023 Barthélemy NR, Saef B, Li Y, Gordon BA, He Y, Horie K, Stomrud E, Salvadó G, Janelidze S, Sato C, Ovod V, Henson RL, Fagan AM, Benzinger TLS, Xiong C, ... ... Bateman RJ, et al. CSF tau phosphorylation occupancies at T217 and T205 represent improved biomarkers of amyloid and tau pathology in Alzheimer's disease. Nature Aging. 3: 391-401. PMID 37117788 DOI: 10.1038/s43587-023-00380-7  0.738
2023 Ali M, Archer DB, Gorijala P, Western D, Timsina J, Fernández MV, Wang TC, Satizabal CL, Yang Q, Beiser AS, Wang R, Chen G, Gordon B, Benzinger TLS, Xiong C, ... ... Bateman RJ, et al. Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease. Acta Neuropathologica Communications. 11: 68. PMID 37101235 DOI: 10.1186/s40478-023-01563-4  0.537
2023 Xu Y, Aung HL, Bateman RJ, Brooks WS, Chhatwal J, Day GS, Fagan AM, Farlow MR, Gordon B, Kehoe PG, Levin J, Mori H, Morris JC, Wharton W, Humburg P, et al. Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37087693 DOI: 10.1002/alz.13082  0.533
2023 Brase L, You SF, D'Oliveira Albanus R, Del-Aguila JL, Dai Y, Novotny BC, Soriano-Tarraga C, Dykstra T, Fernandez MV, Budde JP, Bergmann K, Morris JC, Bateman RJ, Perrin RJ, McDade E, et al. Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers. Nature Communications. 14: 2314. PMID 37085492 DOI: 10.1038/s41467-023-37437-5  0.6
2023 Lawler PE, Bollinger JG, Schindler SE, Hodge CR, Iglesias NJ, Krishnan V, Coulton JB, Li Y, Holtzman DM, Bateman RJ. Apolipoprotein E O-glycosylation is associated with amyloid plaques and APOE genotype. Analytical Biochemistry. 672: 115156. PMID 37072097 DOI: 10.1016/j.ab.2023.115156  0.533
2023 Merrihew GE, Park J, Plubell D, Searle BC, Keene CD, Larson EB, Bateman R, Perrin RJ, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Montine TJ, et al. A peptide-centric quantitative proteomics dataset for the phenotypic assessment of Alzheimer's disease. Scientific Data. 10: 206. PMID 37059743 DOI: 10.1038/s41597-023-02057-7  0.694
2023 Chen CD, McCullough A, Gordon B, Joseph-Mathurin N, Flores S, McKay NS, Hobbs DA, Hornbeck R, Fagan AM, Cruchaga C, Goate AM, Perrin RJ, Wang G, Li Y, Shi X, ... ... Bateman RJ, et al. Longitudinal head-to-head comparison of C-PiB and F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. PMID 37017737 DOI: 10.1007/s00259-023-06209-0  0.708
2023 Xu J, Farsad HL, Hou Y, Barclay K, Lopez BA, Yamada S, Saliu IO, Shi Y, Knight WC, Bateman RJ, Benzinger TLS, Yi JJ, Li Q, Wang T, Perlmutter JS, et al. Human striatal glia differentially contribute to AD- and PD-specific neurodegeneration. Nature Aging. 3: 346-365. PMID 36993867 DOI: 10.1038/s43587-023-00363-8  0.344
2023 Janelidze S, Barthélemy NR, He Y, Bateman RJ, Hansson O. Mitigating the Associations of Kidney Dysfunction With Blood Biomarkers of Alzheimer Disease by Using Phosphorylated Tau to Total Tau Ratios. Jama Neurology. 80: 516-522. PMID 36987840 DOI: 10.1001/jamaneurol.2023.0199  0.413
2023 Fogelman I, West T, Braunstein JB, Verghese PB, Kirmess KM, Meyer MR, Contois JH, Shobin E, Ferber KL, Gagnon J, Rubel CE, Graham D, Bateman RJ, Holtzman DM, Huang S, et al. Independent study demonstrates amyloid probability score accurately indicates amyloid pathology. Annals of Clinical and Translational Neurology. PMID 36975407 DOI: 10.1002/acn3.51763  0.841
2023 Cullen NC, Janelidze S, Stomrud E, Bateman RJ, Palmqvist S, Hansson O, Mattsson-Carlgren N. Plasma amyloid-β42/40 and apolipoprotein E for amyloid PET pre-screening in secondary prevention trials of Alzheimer's disease. Brain Communications. 5: fcad015. PMID 36926368 DOI: 10.1093/braincomms/fcad015  0.318
2023 Lucey BP, Liu H, Toedebusch CD, Freund D, Redrick T, Chahin SL, Mawuenyega KG, Bollinger JG, Ovod V, Barthélemy NR, Bateman RJ. Suvorexant acutely decreases tau phosphorylation and Aβ in the human CNS. Annals of Neurology. PMID 36897120 DOI: 10.1002/ana.26641  0.401
2023 Wisch JK, Gordon BA, Boerwinkle AH, Luckett PH, Bollinger JG, Ovod V, Li Y, Henson RL, West T, Meyer MR, Kirmess KM, Benzinger TLS, Fagan AM, Morris JC, Bateman RJ, et al. Predicting continuous amyloid PET values with CSF and plasma Aβ42/Aβ40. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12405. PMID 36874595 DOI: 10.1002/dad2.12405  0.729
2023 Horie K, Li Y, Barthélemy NR, Gordon BA, Hassenstab J, Benzinger TLS, Fagan AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, Ikeuchi T, Kasuga K, Noble J, ... ... Bateman RJ, et al. Change in cerebrospinal fluid tau microtubule binding region detects symptom onset, cognitive decline, tangles, and atrophy in Dominantly Inherited Alzheimer's Disease. Annals of Neurology. PMID 36843330 DOI: 10.1002/ana.26620  0.744
2023 Liu H, Barthélemy NR, Ovod V, Bollinger JG, He Y, Chahin SL, Androff B, Bateman RJ, Lucey BP. Acute sleep loss decreases CSF-to-blood clearance of Alzheimer's disease biomarkers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36695437 DOI: 10.1002/alz.12930  0.308
2023 Xiong C, McCue LM, Buckles V, Grant E, Agboola F, Coble D, Bateman RJ, Fagan AM, Benzinger TLS, Hassenstab J, Schindler SE, McDade E, Moulder K, Gordon BA, Cruchaga C, et al. Cross-sectional and longitudinal comparisons of biomarkers and cognition among asymptomatic middle-aged individuals with a parental history of either autosomal dominant or late-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36640138 DOI: 10.1002/alz.12912  0.598
2023 Millar PR, Gordon BA, Luckett PH, Benzinger TLS, Cruchaga C, Fagan AM, Hassenstab J, Perrin RJ, Schindler SE, Allegri RF, Day GS, Farlow MR, Mori H, Nübling G, Bateman RJ, et al. Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study. Elife. 12. PMID 36607335 DOI: 10.7554/eLife.81869  0.71
2022 Chatterjee P, Vermunt L, Gordon BA, Pedrini S, Boonkamp L, Armstrong NJ, Xiong C, Singh AK, Li Y, Sohrabi HR, Taddei K, Molloy M, Benzinger TLS, Morris JC, Karch C, ... ... Bateman RJ, et al. Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36576155 DOI: 10.1002/alz.12879  0.75
2022 Brand AL, Lawler PE, Bollinger JG, Li Y, Schindler SE, Li M, Lopez S, Ovod V, Nakamura A, Shaw LM, Zetterberg H, Hansson O, Bateman RJ. The performance of plasma amyloid beta measurements in identifying amyloid plaques in Alzheimer's disease: a literature review. Alzheimer's Research & Therapy. 14: 195. PMID 36575454 DOI: 10.1186/s13195-022-01117-1  0.464
2022 McDade E, Cummings JL, Dhadda S, Swanson CJ, Reyderman L, Kanekiyo M, Koyama A, Irizarry M, Kramer LD, Bateman RJ. Lecanemab in patients with early Alzheimer's disease: detailed results on biomarker, cognitive, and clinical effects from the randomized and open-label extension of the phase 2 proof-of-concept study. Alzheimer's Research & Therapy. 14: 191. PMID 36544184 DOI: 10.1186/s13195-022-01124-2  0.405
2022 O'Connor A, Rice H, Barnes J, Ryan NS, Liu KY, Allegri RF, Berman S, Ringman JM, Cruchaga C, Farlow MR, Hassenstab J, Lee JH, Perrin RJ, Xiong C, Gordon B, ... ... Bateman R, et al. First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 36522155 DOI: 10.1136/jnnp-2022-329843  0.721
2022 Boerwinkle AH, Gordon BA, Wisch J, Flores S, Henson RL, Butt OH, McKay N, Chen CD, Benzinger TLS, Fagan AM, Handen BL, Christian BT, Head E, Mapstone M, Rafii MS, ... ... Bateman RJ, et al. Comparison of amyloid burden in individuals with Down syndrome versus autosomal dominant Alzheimer's disease: a cross-sectional study. The Lancet. Neurology. 22: 55-65. PMID 36517172 DOI: 10.1016/S1474-4422(22)00408-2  0.75
2022 Ashton NJ, Janelidze S, Mattsson-Carlgren N, Binette AP, Strandberg O, Brum WS, Karikari TK, González-Ortiz F, Di Molfetta G, Meda FJ, Jonaitis EM, Koscik RL, Cody K, Betthauser TJ, Li Y, ... ... Bateman RJ, et al. Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer's trial selection and disease monitoring. Nature Medicine. PMID 36456833 DOI: 10.1038/s41591-022-02074-w  0.49
2022 van Dyck CH, Swanson CJ, Aisen P, Bateman RJ, Chen C, Gee M, Kanekiyo M, Li D, Reyderman L, Cohen S, Froelich L, Katayama S, Sabbagh M, Vellas B, Watson D, et al. Lecanemab in Early Alzheimer's Disease. The New England Journal of Medicine. PMID 36449413 DOI: 10.1056/NEJMoa2212948  0.609
2022 Bateman RJ, Cummings J, Schobel S, Salloway S, Vellas B, Boada M, Black SE, Blennow K, Fontoura P, Klein G, Assunção SS, Smith J, Doody RS. Gantenerumab: an anti-amyloid monoclonal antibody with potential disease-modifying effects in early Alzheimer's disease. Alzheimer's Research & Therapy. 14: 178. PMID 36447240 DOI: 10.1186/s13195-022-01110-8  0.402
2022 Horie K, Barthélemy NR, Spina S, VandeVrede L, He Y, Paterson RW, Wright BA, Day GS, Davis AA, Karch CM, Seeley WW, Perrin RJ, Koppisetti RK, Shaikh F, Lago AL, ... ... Bateman RJ, et al. CSF tau microtubule-binding region identifies pathological changes in primary tauopathies. Nature Medicine. PMID 36424467 DOI: 10.1038/s41591-022-02075-9  0.769
2022 Drieu A, Du S, Storck SE, Rustenhoven J, Papadopoulos Z, Dykstra T, Zhong F, Kim K, Blackburn S, Mamuladze T, Harari O, Karch CM, Bateman RJ, Perrin R, Farlow M, et al. Parenchymal border macrophages regulate the flow dynamics of the cerebrospinal fluid. Nature. PMID 36352225 DOI: 10.1038/s41586-022-05397-3  0.61
2022 Wang G, Li Y, Xiong C, McDade E, Clifford DB, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, Libre-Guerra JJ, McCullough A, ... ... Bateman RJ, et al. Evaluation of dose-dependent treatment effects after mid-trial dose escalation in biomarker, clinical, and cognitive outcomes for gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 14: e12367. PMID 36348972 DOI: 10.1002/dad2.12367  0.456
2022 Novotny BC, Fernandez MV, Wang C, Budde JP, Bergmann K, Eteleeb AM, Bradley J, Webster C, Ebl C, Norton J, Gentsch J, Dube U, Wang F, Morris JC, Bateman RJ, et al. Metabolomic and lipidomic signatures in autosomal dominant and late-onset Alzheimer's disease brains. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36251323 DOI: 10.1002/alz.12800  0.666
2022 Warren-Gash C, Cadogan SL, Nicholas JM, Breuer JM, Shah D, Pearce N, Shiekh S, Smeeth L, Farlow MR, Mori H, Gordon BA, Nuebling G, McDade E, Bateman RJ, Schofield PR, et al. Herpes simplex virus and rates of cognitive decline or whole brain atrophy in the Dominantly Inherited Alzheimer Network. Annals of Clinical and Translational Neurology. PMID 36189728 DOI: 10.1002/acn3.51669  0.497
2022 Aschenbrenner AJ, Li Y, Henson RL, Volluz K, Hassenstab J, Verghese P, West T, Meyer MR, Kirmess KM, Fagan AM, Xiong C, Holtzman D, Morris JC, Bateman RJ, Schindler SE. Comparison of plasma and CSF biomarkers in predicting cognitive decline. Annals of Clinical and Translational Neurology. PMID 36183195 DOI: 10.1002/acn3.51670  0.808
2022 Pichet Binette A, Janelidze S, Cullen N, Dage JL, Bateman RJ, Zetterberg H, Blennow K, Stomrud E, Mattsson-Carlgren N, Hansson O. Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36152307 DOI: 10.1002/alz.12787  0.373
2022 Joseph-Mathurin N, Llibre-Guerra JJ, Li Y, McCullough AA, Hofmann C, Wojtowicz J, Park E, Wang G, Preboske GM, Wang Q, Gordon BA, Chen CD, Flores S, Aggarwal NT, Berman SB, ... ... Bateman RJ, et al. Amyloid-related imaging abnormalities in the DIAN-TU-001 trial of gantenerumab and solanezumab: lessons from a trial in dominantly inherited Alzheimer disease. Annals of Neurology. PMID 36151869 DOI: 10.1002/ana.26511  0.717
2022 Janelidze S, Bali D, Ashton NJ, Barthélemy NR, Vanbrabant J, Stoops E, Vanmechelen E, He Y, Dolado AO, Triana-Baltzer G, Pontecorvo MJ, Zetterberg H, Kolb H, Vandijck M, Blennow K, ... Bateman RJ, et al. Head-to-head comparison of 10 plasma phospho-tau assays in prodromal Alzheimer's disease. Brain : a Journal of Neurology. PMID 36087307 DOI: 10.1093/brain/awac333  0.358
2022 Nicosia J, Aschenbrenner AJ, Balota DA, Sliwinski MJ, Tahan M, Adams S, Stout SS, Wilks H, Gordon BA, Benzinger TLS, Fagan AM, Xiong C, Bateman RJ, Morris JC, Hassenstab J. Unsupervised high-frequency smartphone-based cognitive assessments are reliable, valid, and feasible in older adults at risk for Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 1-13. PMID 36062528 DOI: 10.1017/S135561772200042X  0.512
2022 Dobrowolska Zakaria JA, Bateman RJ, Lysakowska M, Khatri A, Jean-Gilles D, Kennedy ME, Vassar R. The metabolism of human soluble amyloid precursor protein isoforms is quantifiable by a stable isotope labeling-tandem mass spectrometry method. Scientific Reports. 12: 14985. PMID 36056033 DOI: 10.1038/s41598-022-18869-3  0.398
2022 Schindler SE, Li Y, Li M, Despotis A, Park E, Vittert L, Hamilton BH, Womack KB, Saef B, Holtzman DM, Morris JC, Bateman RJ, Gupta MR. Using Alzheimer's disease blood tests to accelerate clinical trial enrollment. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35934777 DOI: 10.1002/alz.12754  0.535
2022 Takada LT, Aláez-Verson C, Burgute BD, Nitrini R, Sosa AL, Castilhos RM, Chaves MF, Longoria EM, Carrillo-Sánchez K, Brucki SMD, Flores-Lagunes LL, Molina C, Olivares MJ, Ziegemeier E, Petranek J, ... ... Bateman RJ, et al. Discovery and validation of dominantly inherited Alzheimer's disease mutations in populations from Latin America. Alzheimer's Research & Therapy. 14: 108. PMID 35932032 DOI: 10.1186/s13195-022-01052-1  0.311
2022 Luo J, Agboola F, Grant E, Morris JC, Masters CL, Albert MS, Johnson SC, McDade EM, Fagan AM, Benzinger TLS, Hassenstab J, Bateman RJ, Perrin RJ, Wang G, Li Y, et al. Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan. Brain : a Journal of Neurology. PMID 35925685 DOI: 10.1093/brain/awac238  0.747
2022 Strain JF, Brier MR, Tanenbaum A, Gordon BA, McCarthy JE, Dincer A, Marcus DS, Chhatwal JP, Graff-Radford NR, Day GS, la Fougère C, Perrin RJ, Salloway S, Schofield PR, Yakushev I, ... ... Bateman RJ, et al. Covariance-based vs. Correlation-based Functional Connectivity Dissociates Healthy Aging from Alzheimer Disease. Neuroimage. 119511. PMID 35914670 DOI: 10.1016/j.neuroimage.2022.119511  0.692
2022 Dokholyan NV, Mohs RC, Bateman RJ. Challenges and progress in research, diagnostics, and therapeutics in Alzheimer's disease and related dementias. Alzheimer's & Dementia (New York, N. Y.). 8: e12330. PMID 35910674 DOI: 10.1002/trc2.12330  0.381
2022 Timsina J, Gomez-Fonseca D, Wang L, Do A, Western D, Alvarez I, Aguilar M, Pastor P, Henson RL, Herries E, Xiong C, Schindler SE, Fagan AM, Bateman RJ, Farlow M, et al. Comparative Analysis of Alzheimer's Disease Cerebrospinal Fluid Biomarkers Measurement by Multiplex SOMAscan Platform and Immunoassay-Based Approach. Journal of Alzheimer's Disease : Jad. PMID 35871346 DOI: 10.3233/JAD-220399  0.581
2022 Zicha S, Bateman RJ, Shaw LM, Zetterberg H, Bannon AW, Horton WA, Baratta M, Kolb HC, Dobler I, Mordashova Y, Saad ZS, Raunig DL, Spanakis EM, Li Y, Schindler SE, et al. Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35820077 DOI: 10.1002/alz.12697  0.311
2022 Capano LS, Sato C, Ficulle E, Yu A, Horie K, Kwon JS, Burbach KF, Barthélemy NR, Fox SG, Karch CM, Bateman RJ, Houlden H, Morimoto RI, Holtzman DM, Duff KE, et al. Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons. Cell Stem Cell. 29: 918-932.e8. PMID 35659876 DOI: 10.1016/j.stem.2022.04.018  0.601
2022 Vöglein J, Franzmeier N, Morris JC, Dieterich M, McDade E, Simons M, Preische O, Hofmann A, Hassenstab J, Benzinger TL, Fagan A, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, ... ... Bateman RJ, et al. Patterns and implications of neurological examination findings in autosomal dominant Alzheimer disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35609137 DOI: 10.1002/alz.12684  0.639
2022 Morris JC, Weiner M, Xiong C, Beckett L, Coble D, Saito N, Aisen PS, Allegri R, Benzinger TLS, Berman SB, Cairns NJ, Carrillo MC, Chui HC, Chhatwal JP, Cruchaga C, ... ... Bateman RJ, et al. Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. Brain : a Journal of Neurology. PMID 35580594 DOI: 10.1093/brain/awac181  0.676
2022 Millar PR, Luckett PH, Gordon BA, Benzinger TL, Schindler SE, Fagan AM, Cruchaga C, Bateman RJ, Allegri R, Jucker M, Lee JH, Mori H, Salloway SP, Yakushev I, Morris JC, et al. Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease. Neuroimage. 119228. PMID 35452806 DOI: 10.1016/j.neuroimage.2022.119228  0.586
2022 Schindler SE, Karikari TK, Ashton NJ, Henson RL, Yarasheski KE, West T, Meyer MR, Kirmess KM, Li Y, Saef B, Moulder KL, Bradford D, Fagan AM, Gordon BA, Benzinger TLS, ... ... Bateman RJ, et al. Effect of Race on Prediction of Brain Amyloidosis by Plasma Aβ42/Aβ40, Phosphorylated Tau, and Neurofilament Light. Neurology. PMID 35450967 DOI: 10.1212/WNL.0000000000200358  0.716
2022 Hu Y, Kirmess KM, Meyer MR, Rabinovici GD, Gatsonis C, Siegel BA, Whitmer RA, Apgar C, Hanna L, Kanekiyo M, Kaplow J, Koyama A, Verbel D, Holubasch MS, Knapik SS, ... ... Bateman RJ, et al. Assessment of a Plasma Amyloid Probability Score to Estimate Amyloid Positron Emission Tomography Findings Among Adults With Cognitive Impairment. Jama Network Open. 5: e228392. PMID 35446396 DOI: 10.1001/jamanetworkopen.2022.8392  0.828
2022 Lu WH, Giudici KV, Morley JE, Guyonnet S, Parini A, Aggarwal G, Nguyen AD, Li Y, Bateman RJ, Vellas B, de Souto Barreto P. Investigating the combination of plasma amyloid-beta and geroscience biomarkers on the incidence of clinically meaningful cognitive decline in older adults. Geroscience. PMID 35445358 DOI: 10.1007/s11357-022-00554-y  0.374
2022 Budelier MM, He Y, Barthelemy NR, Jiang H, Li Y, Park E, Henson RL, Schindler SE, Holtzman DM, Bateman RJ. A map of neurofilament light chain species in brain and cerebrospinal fluid and alterations in Alzheimer's disease. Brain Communications. 4: fcac045. PMID 35415607 DOI: 10.1093/braincomms/fcac045  0.483
2022 Luckett PH, Chen C, Gordon BA, Wisch J, Berman SB, Chhatwal JP, Cruchaga C, Fagan AM, Farlow MR, Fox NC, Jucker M, Levin J, Masters CL, Mori H, Noble JM, ... ... Bateman RJ, et al. Biomarker clustering in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35362200 DOI: 10.1002/alz.12661  0.741
2022 Strain JF, Barthelemy N, Horie K, Gordon BA, Kilgore C, Aschenbrenner A, Cruchaga C, Xiong C, Joseph-Mathurin N, Hassenstab J, Fagan AM, Li Y, Karch CM, Perrin RJ, Berman SB, ... ... Bateman RJ, et al. CSF Tau phosphorylation at Thr205 is associated with loss of white matter integrity in autosomal dominant Alzheimer disease. Neurobiology of Disease. 168: 105714. PMID 35358703 DOI: 10.1016/j.nbd.2022.105714  0.779
2022 Morenas-Rodríguez E, Li Y, Nuscher B, Franzmeier N, Xiong C, Suárez-Calvet M, Fagan AM, Schultz S, Gordon BA, Benzinger TLS, Hassenstab J, McDade E, Feederle R, Karch CM, Schlepckow K, ... ... Bateman RJ, et al. Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study. The Lancet. Neurology. 21: 329-341. PMID 35305339 DOI: 10.1016/S1474-4422(22)00027-8  0.666
2022 Chen HH, Eteleeb A, Wang C, Fernandez MV, Budde JP, Bergmann K, Norton J, Wang F, Ebl C, Morris JC, Perrin RJ, Bateman RJ, McDade E, Xiong C, Goate A, et al. Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease. Acta Neuropathologica Communications. 10: 29. PMID 35246267 DOI: 10.1186/s40478-022-01328-5  0.618
2022 Levin J, Vöglein J, Quiroz YT, Bateman RJ, Ghisays V, Lopera F, McDade E, Reiman E, Tariot PN, Morris JC. Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35212149 DOI: 10.1002/alz.12624  0.47
2022 Jansen WJ, Janssen O, Tijms BM, Vos SJB, Ossenkoppele R, Visser PJ, Aarsland D, Alcolea D, Altomare D, von Arnim C, Baiardi S, Baldeiras I, Barthel H, Bateman RJ, et al. Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum. Jama Neurology. PMID 35099509 DOI: 10.1001/jamaneurol.2021.5216  0.407
2022 Lim YY, Maruff P, Barthélemy NR, Goate A, Hassenstab J, Sato C, Fagan AM, Benzinger TLS, Xiong C, Cruchaga C, Levin J, Farlow MR, Graff-Radford NR, Laske C, Masters CL, ... ... Bateman RJ, et al. Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease. Jama Neurology. PMID 35099506 DOI: 10.1001/jamaneurol.2021.5181  0.65
2022 Elbert DL, Patterson BW, Lucey BP, Benzinger TLS, Bateman RJ. Importance of CSF-based Aβ clearance with age in humans increases with declining efficacy of blood-brain barrier/proteolytic pathways. Communications Biology. 5: 98. PMID 35087179 DOI: 10.1038/s42003-022-03037-0  0.35
2022 Chhatwal JP, Schultz SA, McDade E, Schultz AP, Liu L, Hanseeuw BJ, Joseph-Mathurin N, Feldman R, Fitzpatrick CD, Sparks KP, Levin J, Berman SB, Renton AE, Esposito BT, Fernandez MV, ... ... Bateman RJ, et al. Variant-dependent heterogeneity in amyloid β burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study. The Lancet. Neurology. 21: 140-152. PMID 35065037 DOI: 10.1016/S1474-4422(21)00375-6  0.762
2021 Li Y, Schindler SE, Bollinger JG, Ovod V, Mawuenyega KG, Weiner MW, Leslie SM, Masters CL, Fowler CJ, Trojanowski JQ, Korecka M, Martins RN, Janelidze S, Hansson O, Bateman RJ. Validation of Plasma Amyloid-β 42/40 for Detecting Alzheimer Disease Amyloid Plaques. Neurology. PMID 34906975 DOI: 10.1212/WNL.0000000000013211  0.434
2021 Ezerskiy LA, Schoch KM, Sato C, Beltcheva M, Horie K, Rigo F, Martynowicz R, Karch CM, Bateman RJ, Miller TM. Astrocytic 4R tau expression drives astrocyte reactivity and dysfunction. Jci Insight. PMID 34874917 DOI: 10.1172/jci.insight.152012  0.547
2021 Hubbard EE, Heil LR, Merrihew GE, Chhatwal JP, Farlow MR, McLean CA, Ghetti B, Newell KL, Frosch MP, Bateman RJ, Larson EB, Keene CD, Perrin RJ, Montine TJ, MacCoss MJ, et al. Does Data-Independent Acquisition Data Contain Hidden Gems? A Case Study Related to Alzheimer's Disease. Journal of Proteome Research. PMID 34818016 DOI: 10.1021/acs.jproteome.1c00558  0.661
2021 Barthélemy NR, Toth B, Manser PT, Sanabria-Bohórquez S, Teng E, Keeley M, Bateman RJ, Weimer RM, Wildsmith KR. Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer's Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated. Journal of Alzheimer's Disease : Jad. PMID 34806603 DOI: 10.3233/JAD-210677  0.457
2021 Pannee J, Shaw LM, Korecka M, Waligorska T, Teunissen CE, Stoops E, Vanderstichele HMJ, Mauroo K, Verberk IMW, Keshavan A, Pesini P, Sarasa L, Pascual-Lucas M, Fandos N, Allué JA, ... ... Bateman RJ, et al. The global Alzheimer's Association round robin study on plasma amyloid β methods. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12242. PMID 34692980 DOI: 10.1002/dad2.12242  0.365
2021 Koenig LN, LaMontagne P, Glasser MF, Bateman R, Holtzman D, Yakushev I, Chhatwal J, Day GS, Jack C, Mummery C, Perrin RJ, Gordon BA, Morris JC, Shimony JS, Benzinger TLS, et al. Regional age-related atrophy after screening for preclinical alzheimer disease. Neurobiology of Aging. 109: 43-51. PMID 34655980 DOI: 10.1016/j.neurobiolaging.2021.09.010  0.673
2021 McDade E, Voytyuk I, Aisen P, Bateman RJ, Carrillo MC, De Strooper B, Haass C, Reiman EM, Sperling R, Tariot PN, Yan R, Masters CL, Vassar R, Lichtenthaler SF. The case for low-level BACE1 inhibition for the prevention of Alzheimer disease. Nature Reviews. Neurology. PMID 34548654 DOI: 10.1038/s41582-021-00545-1  0.379
2021 Janelidze S, Teunissen CE, Zetterberg H, Allué JA, Sarasa L, Eichenlaub U, Bittner T, Ovod V, Verberk IMW, Toba K, Nakamura A, Bateman RJ, Blennow K, Hansson O. Head-to-Head Comparison of 8 Plasma Amyloid-β 42/40 Assays in Alzheimer Disease. Jama Neurology. PMID 34542571 DOI: 10.1001/jamaneurol.2021.3180  0.416
2021 Gonneaud J, Baria AT, Pichet Binette A, Gordon BA, Chhatwal JP, Cruchaga C, Jucker M, Levin J, Salloway S, Farlow M, Gauthier S, Benzinger TLS, Morris JC, Bateman RJ, Breitner JCS, et al. Accelerated functional brain aging in pre-clinical familial Alzheimer's disease. Nature Communications. 12: 5346. PMID 34504080 DOI: 10.1038/s41467-021-25492-9  0.616
2021 Schindler S, Li Y, Buckles VD, Gordon BA, Benzinger TLS, Wang G, Coble D, Klunk WE, Fagan AM, Holtzman D, Bateman RJ, Morris JC, Xiong C. Predicting Symptom Onset in Sporadic Alzheimer Disease With Amyloid PET. Neurology. PMID 34504028 DOI: 10.1212/WNL.0000000000012775  0.687
2021 Sato C, Mallipeddi N, Ghoshal N, Wright BA, Day GS, Davis AA, Kim AH, Zipfel GJ, Bateman RJ, Gabelle A, Barthélemy NR. MAPT R406W increases tau T217 phosphorylation in absence of amyloid pathology. Annals of Clinical and Translational Neurology. PMID 34342183 DOI: 10.1002/acn3.51435  0.645
2021 Chen CD, Joseph-Mathurin N, Sinha N, Zhou A, Li Y, Friedrichsen K, McCullough A, Franklin EE, Hornbeck R, Gordon B, Sharma V, Cruchaga C, Goate A, Karch C, McDade E, ... ... Bateman RJ, et al. Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease. Acta Neuropathologica. PMID 34319442 DOI: 10.1007/s00401-021-02342-y  0.693
2021 Fagan AM, Henson RL, Li Y, Boerwinkle AH, Xiong C, Bateman RJ, Goate A, Ances BM, Doran E, Christian BT, Lai F, Rosas HD, Schupf N, Krinsky-McHale S, Silverman W, et al. Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study. The Lancet. Neurology. 20: 615-626. PMID 34302786 DOI: 10.1016/S1474-4422(21)00139-3  0.388
2021 McDade E, Llibre-Guerra JJ, Holtzman DM, Morris JC, Bateman RJ. The informed road map to prevention of Alzheimer Disease: A call to arms. Molecular Neurodegeneration. 16: 49. PMID 34289882 DOI: 10.1186/s13024-021-00467-y  0.563
2021 Horie K, Barthélemy NR, Sato C, Bateman RJ. Corrigendum to: CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease. Brain : a Journal of Neurology. PMID 34215872 DOI: 10.1093/brain/awab227  0.642
2021 Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, ... ... Bateman RJ, et al. A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Nature Medicine. PMID 34155411 DOI: 10.1038/s41591-021-01369-8  0.71
2021 Pichet Binette A, Theaud G, Rheault F, Roy M, Collins DL, Levin J, Mori H, Lee JH, Farlow MR, Schofield P, Chhatwal JP, Masters CL, Benzinger T, Morris J, Bateman R, et al. Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease. Elife. 10. PMID 33983116 DOI: 10.7554/eLife.62929  0.477
2021 Mattsson-Carlgren N, Janelidze S, Bateman RJ, Smith R, Stomrud E, Serrano GE, Reiman EM, Palmqvist S, Dage JL, Beach TG, Hansson O. Soluble P-tau217 reflects amyloid and tau pathology and mediates the association of amyloid with tau. Embo Molecular Medicine. e14022. PMID 33949133 DOI: 10.15252/emmm.202114022  0.431
2021 West T, Kirmess KM, Meyer MR, Holubasch MS, Knapik SS, Hu Y, Contois JH, Jackson EN, Harpstrite SE, Bateman RJ, Holtzman DM, Verghese PB, Fogelman I, Braunstein JB, Yarasheski KE. A blood-based diagnostic test incorporating plasma Aβ42/40 ratio, ApoE proteotype, and age accurately identifies brain amyloid status: findings from a multi cohort validity analysis. Molecular Neurodegeneration. 16: 30. PMID 33933117 DOI: 10.1186/s13024-021-00451-6  0.829
2021 Tosun D, Veitch D, Aisen P, Jack CR, Jagust WJ, Petersen RC, Saykin AJ, Bollinger J, Ovod V, Mawuenyega KG, Bateman RJ, Shaw LM, Trojanowski JQ, Blennow K, Zetterberg H, et al. Detection of β-amyloid positivity in Alzheimer's Disease Neuroimaging Initiative participants with demographics, cognition, MRI and plasma biomarkers. Brain Communications. 3: fcab008. PMID 33842885 DOI: 10.1093/braincomms/fcab008  0.341
2021 Chatterjee P, Tegg M, Pedrini S, Fagan AM, Xiong C, Singh AK, Taddei K, Gardener S, Masters CL, Schofield PR, Multhaup G, Benzinger TLS, Morris JC, Bateman RJ, Greenberg SM, et al. Plasma Amyloid-Beta Levels in a Pre-Symptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross-Sectional and Longitudinal Investigation. International Journal of Molecular Sciences. 22. PMID 33805778 DOI: 10.3390/ijms22062931  0.338
2021 Ewers M, Luan Y, Frontzkowski L, Neitzel J, Rubinski A, Dichgans M, Hassenstab J, Gordon BA, Chhatwal JP, Levin J, Schofield P, Benzinger TLS, Morris JC, Goate A, Karch CM, ... ... Bateman RJ, et al. Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease. Brain : a Journal of Neurology. PMID 33725114 DOI: 10.1093/brain/awab112  0.732
2021 Joseph-Mathurin N, Wang G, Kantarci K, Jack CR, McDade E, Hassenstab J, Blazey TM, Gordon BA, Su Y, Chen G, Massoumzadeh P, Hornbeck RC, Allegri RF, Ances BM, Berman SB, ... ... Bateman RJ, et al. Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease. Neurology. PMID 33495373 DOI: 10.1212/WNL.0000000000011542  0.711
2021 Luckett PH, McCullough A, Gordon BA, Strain J, Flores S, Dincer A, McCarthy J, Kuffner T, Stern A, Meeker KL, Berman SB, Chhatwal JP, Cruchaga C, Fagan AM, Farlow MR, ... ... Bateman RJ, et al. Modeling autosomal dominant Alzheimer's disease with machine learning. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480178 DOI: 10.1002/alz.12259  0.682
2021 Smith R, Strain J, Tanenbaum A, Fagan A, Hassenstab J, Mcdade E, Schindler S, Gordon B, Xiong C, Chhatwal J, Jack CR, Karch C, Berman S, Brosch J, Lah J, ... ... Bateman R, et al. Resting-State Functional Connectivity Disruption as a Pathological Biomarker in Autosomal Dominant Alzheimer Disease. Brain Connectivity. PMID 33430685 DOI: 10.1089/brain.2020.0808  0.656
2020 Dincer A, Gordon BA, Hari-Raj A, Keefe SJ, Flores S, McKay NS, Paulick AM, Shady Lewis KE, Feldman RL, Hornbeck RC, Allegri R, Ances BM, Berman SB, Brickman AM, Brooks WS, ... ... Bateman RJ, et al. Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease. Neuroimage. Clinical. 28: 102491. PMID 33395982 DOI: 10.1016/j.nicl.2020.102491  0.695
2020 Horie K, Barthélemy NR, Sato C, Bateman RJ. CSF tau microtubule binding region identifies tau tangle and clinical stages of Alzheimer's disease. Brain : a Journal of Neurology. PMID 33283854 DOI: 10.1093/brain/awaa373  0.685
2020 Llibre-Guerra JJ, Li Y, Allegri RF, Mendez PC, Surace EI, Llibre-Rodriguez JJ, Sosa AL, Aláez-Verson C, Longoria EM, Tellez A, Carrillo-Sánchez K, Flores-Lagunes LL, Sánchez V, Takada LT, Nitrini R, ... ... Bateman RJ, et al. Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33226734 DOI: 10.1002/alz.12227  0.328
2020 Montal V, Vilaplana E, Pegueroles J, Bejanin A, Alcolea D, Carmona-Iragui M, Clarimón J, Levin J, Cruchaga C, Graff-Radford NR, Noble JM, Lee JH, Allegri R, Karch CM, Laske C, ... ... Bateman R, et al. Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33196147 DOI: 10.1002/alz.12224  0.456
2020 Chen CD, Holden TR, Gordon BA, Franklin EE, Li Y, Coble DW, Luo H, Bateman RJ, Ances BM, Perrin RJ, Benzinger TLS, Cairns NJ, Morris JC. Ante- and postmortem tau in autosomal dominant and late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. PMID 33150749 DOI: 10.1002/acn3.51237  0.765
2020 Vermunt L, Dicks E, Wang G, Dincer A, Flores S, Keefe SJ, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Fox NC, Ghetti B, Graff-Radford NR, Hassenstab J, Karch CM, ... ... Bateman RJ, et al. Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease. Brain Communications. 2: fcaa102. PMID 32954344 DOI: 10.1093/braincomms/fcaa102  0.708
2020 Luo J, Agboola F, Grant E, Masters CL, Albert MS, Johnson SC, McDade EM, Vöglein J, Fagan AM, Benzinger T, Massoumzadeh P, Hassenstab J, Bateman RJ, Morris JC, Perrin RJ, et al. Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study. Neurology. PMID 32873693 DOI: 10.1212/Wnl.0000000000010747  0.647
2020 Horie K, Barthélemy NR, Mallipeddi N, Li Y, Franklin EE, Perrin RJ, Bateman RJ, Sato C. Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brain. Acta Neuropathologica Communications. 8: 149. PMID 32854776 DOI: 10.1186/S40478-020-01019-Z  0.751
2020 Li H, Knight WC, Yang P, Guo Y, Perlmutter JS, Morris JC, Bateman RJ, Benzinger TLS, Xu J. Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype. International Journal of Molecular Sciences. 21. PMID 32842621 DOI: 10.3390/Ijms21176047  0.371
2020 Gonneaud J, Bedetti C, Binette AP, Benzinger TLS, Morris JC, Bateman RJ, Poirier J, Breitner JCS, Villeneuve S. Association of education with Aβ burden in preclinicial familial and sporadic Alzheimer disease. Neurology. PMID 32759192 DOI: 10.1212/Wnl.0000000000010314  0.411
2020 Barthélemy NR, Horie K, Sato C, Bateman RJ. Blood plasma phosphorylated-tau isoforms track CNS change in Alzheimer's disease. The Journal of Experimental Medicine. 217. PMID 32725127 DOI: 10.1084/Jem.20200861  0.645
2020 Aschenbrenner AJ, Petros J, McDade E, Wang G, Balota DA, Benzinger TL, Cruchaga C, Goate A, Xiong C, Perrin R, Fagan AM, Graff-Radford N, Ghetti B, Levin J, Weidinger E, ... ... Bateman R, et al. Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12038. PMID 32587883 DOI: 10.1002/Dad2.12038  0.709
2020 Schultz SA, Strain JF, Adedokun A, Wang Q, Preische O, Kuhle J, Flores S, Keefe S, Dincer A, Ances BM, Berman SB, Brickman AM, Cash DM, Chhatwal J, Cruchaga C, ... ... Bateman RJ, et al. Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease. Neurobiology of Disease. 104960. PMID 32522711 DOI: 10.1016/J.Nbd.2020.104960  0.668
2020 Pichet Binette A, Vachon-Presseau É, Morris J, Bateman R, Benzinger T, Collins DL, Poirier J, Breitner JCS, Villeneuve S. Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease. Biological Psychiatry. PMID 32228870 DOI: 10.1016/J.Biopsych.2020.01.023  0.527
2020 Barthélemy NR, Bateman RJ, Hirtz C, Marin P, Becher F, Sato C, Gabelle A, Lehmann S. Cerebrospinal fluid phospho-tau T217 outperforms T181 as a biomarker for the differential diagnosis of Alzheimer's disease and PET amyloid-positive patient identification. Alzheimer's Research & Therapy. 12: 26. PMID 32183883 DOI: 10.1186/S13195-020-00596-4  0.668
2020 Barthélemy NR, Li Y, Joseph-Mathurin N, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Perrin RJ, Goate AM, Morris JC, Karch CM, Xiong C, Allegri R, Mendez PC, ... ... Bateman RJ, et al. A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease. Nature Medicine. 26: 398-407. PMID 32161412 DOI: 10.1038/S41591-020-0781-Z  0.808
2020 Bateman RJ, Barthélemy NR, Horie K. Another step forward in blood-based diagnostics for Alzheimer's disease. Nature Medicine. 26: 314-316. PMID 32132715 DOI: 10.1038/s41591-020-0797-4  0.344
2020 Franzmeier N, Koutsouleris N, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Duering M, Dichgans M, Levin J, Gordon BA, Lim YY, Masters CL, Rossor M, Fox NC, ... ... Bateman RJ, et al. Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32043733 DOI: 10.1002/Alz.12032  0.617
2020 Aschenbrenner AJ, James BD, McDade E, Wang G, Lim YY, Benzinger TLS, Cruchaga C, Goate A, Xiong C, Perrin R, Buckles V, Allegri R, Berman SB, Chhatwal JP, Fagan A, ... ... Bateman RJ, et al. Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 219-228. PMID 31914221 DOI: 10.1002/Alz.12010  0.584
2019 Budelier MM, Bateman RJ. Biomarkers of Alzheimer Disease. The Journal of Applied Laboratory Medicine. PMID 31843944 DOI: 10.1373/jalm.2019.030080  0.387
2019 Klein G, Delmar P, Voyle N, Rehal S, Hofmann C, Abi-Saab D, Andjelkovic M, Ristic S, Wang G, Bateman R, Kerchner GA, Baudler M, Fontoura P, Doody R. Gantenerumab reduces amyloid-β plaques in patients with prodromal to moderate Alzheimer's disease: a PET substudy interim analysis. Alzheimer's Research & Therapy. 11: 101. PMID 31831056 DOI: 10.1186/S13195-019-0559-Z  0.462
2019 Llibre-Guerra JJ, Li Y, Schindler SE, Gordon BA, Fagan AM, Morris JC, Benzinger TLS, Hassenstab J, Wang G, Allegri R, Berman SB, Chhatwal J, Farlow MR, Holtzman DM, Jucker M, ... ... Bateman RJ, et al. Association of Longitudinal Changes in Cerebrospinal Fluid Total Tau and Phosphorylated Tau 181 and Brain Atrophy With Disease Progression in Patients With Alzheimer Disease. Jama Network Open. 2: e1917126. PMID 31825500 DOI: 10.1001/jamanetworkopen.2019.17126  0.688
2019 Dube U, Del-Aguila JL, Li Z, Budde JP, Jiang S, Hsu S, Ibanez L, Fernandez MV, Farias F, Norton J, Gentsch J, Wang F, Salloway S, Masters CL, ... ... Bateman RJ, et al. An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations. Nature Neuroscience. PMID 31591557 DOI: 10.1038/S41593-019-0501-5  0.368
2019 Xiong C, Luo J, Agboola F, Li Y, Albert M, Johnson SC, Koscik RL, Masters CL, Soldan A, Villemagne VL, Li QX, McDade EM, Fagan AM, Massoumzadeh P, Benzinger T, ... ... Bateman RJ, et al. A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer's disease from young adulthood and for designing prevention trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31506247 DOI: 10.1016/J.Jalz.2019.06.4955  0.424
2019 Schindler SE, Bollinger JG, Ovod V, Mawuenyega KG, Li Y, Gordon BA, Holtzman DM, Morris JC, Benzinger TLS, Xiong C, Fagan AM, Bateman RJ. High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis. Neurology. PMID 31371569 DOI: 10.1212/Wnl.0000000000008081  0.664
2019 Paterson RW, Gabelle A, Lucey BP, Barthélemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, ... ... Bateman RJ, et al. SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases. Nature Reviews. Neurology. PMID 31222062 DOI: 10.1038/S41582-019-0222-0  0.833
2019 Barthélemy NR, Mallipeddi N, Moiseyev P, Sato C, Bateman RJ. Tau Phosphorylation Rates Measured by Mass Spectrometry Differ in the Intracellular Brain vs. Extracellular Cerebrospinal Fluid Compartments and Are Differentially Affected by Alzheimer's Disease. Frontiers in Aging Neuroscience. 11: 121. PMID 31178717 DOI: 10.3389/Fnagi.2019.00121  0.64
2019 Liebsch F, Kulic L, Teunissen C, Shobo A, Ulku I, Engelschalt V, Hancock MA, van der Flier WM, Kunach P, Rosa-Neto P, Scheltens P, Poirier J, Saftig P, Bateman RJ, Breitner J, et al. Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression. Nature Communications. 10: 2240. PMID 31110178 DOI: 10.1038/S41467-019-10152-W  0.49
2019 Bateman RJ, Blennow K, Doody R, Hendrix S, Lovestone S, Salloway S, Schindler R, Weiner M, Zetterberg H, Aisen P, Vellas B. Plasma Biomarkers of AD Emerging as Essential Tools for Drug Development: An EU/US CTAD Task Force Report. The Journal of Prevention of Alzheimer's Disease. 6: 169-173. PMID 31062827 DOI: 10.14283/jpad.2019.21  0.406
2019 Cummings J, Blennow K, Johnson K, Keeley M, Bateman RJ, Molinuevo JL, Touchon J, Aisen P, Vellas B. Anti-Tau Trials for Alzheimer's Disease: A Report from the EU/US/CTAD Task Force. The Journal of Prevention of Alzheimer's Disease. 6: 157-163. PMID 31062825 DOI: 10.14283/jpad.2019.14  0.441
2019 Bateman RJ, Mawuenyega KG, Wildburger NC. The structure of amyloid-β dimers in Alzheimer's disease brain: a step forward for oligomers. Brain : a Journal of Neurology. 142: 1168-1169. PMID 31032843 DOI: 10.1093/Brain/Awz082  0.793
2019 Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Bateman RJ, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/S41380-019-0404-6  0.599
2019 Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, ... ... Bateman RJ, et al. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30897203 DOI: 10.1093/Brain/Awz050  0.316
2019 Su Y, Flores S, Wang G, Hornbeck RC, Speidel B, Joseph-Mathurin N, Vlassenko AG, Gordon BA, Koeppe RA, Klunk WE, Jack CR, Farlow MR, Salloway S, Snider BJ, Berman SB, ... ... Bateman RJ, et al. Comparison of Pittsburgh compound B and florbetapir in cross-sectional and longitudinal studies. Alzheimer's & Dementia (Amsterdam, Netherlands). 11: 180-190. PMID 30847382 DOI: 10.1016/J.Dadm.2018.12.008  0.482
2019 Schindler SE, Li Y, Todd KW, Herries EM, Henson RL, Gray JD, Wang G, Graham DL, Shaw LM, Trojanowski JQ, Hassenstab JJ, Benzinger TLS, Cruchaga C, Jucker M, Levin J, ... ... Bateman RJ, et al. Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30846386 DOI: 10.1016/J.Jalz.2018.12.019  0.552
2019 Wang G, Coble D, McDade EM, Hassenstab J, Fagan AM, Benzinger TLS, Bateman RJ, Morris JC, Xiong C. Staging biomarkers in preclinical autosomal dominant Alzheimer's disease by estimated years to symptom onset. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30773445 DOI: 10.1016/J.Jalz.2018.12.008  0.386
2019 Gordon BA, Blazey TM, Christensen J, Dincer A, Flores S, Keefe S, Chen C, Su Y, McDade EM, Wang G, Li Y, Hassenstab J, Aschenbrenner A, Hornbeck R, Jack CR, ... ... Bateman RJ, et al. Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers. Brain : a Journal of Neurology. PMID 30753379 DOI: 10.1093/Brain/Awz019  0.708
2019 Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, ... ... Bateman RJ, et al. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease. Nature Medicine. PMID 30664784 DOI: 10.1038/S41591-018-0304-3  0.586
2019 Bateman RJ, Morris JC. A New Era: Disease Modifying Alzheimer Disease Prevention Trials. The Journal of Prevention of Alzheimer's Disease. 1: 68. PMID 29255832 DOI: 10.14283/jpad.2014.12  0.332
2019 Strain JF, Wisch J, Kilgore CB, McDade E, Li Y, Barthélemy NR, Gordon BA, Hassenstab J, Fagan AM, Morris JC, Benzinger TLS, Bateman R, Ances BM, Dian. Ic‐P‐098: Phosphorylation Of Specific Tau Sites Is Associated With Loss Of White Matter Integrity In Autosomal Dominant Alzheimer Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4941  0.607
2019 Schultz SA, Adedokun A, Strain JF, Wang Q, Preische O, Kuhle J, Morris JC, Bateman R, Jucker M, Gordon BA, Benzinger TLS. Ic-P-094: Cross-Sectional And Longitudinal Association Between Serum Neurofilament Light And Established White Matter Neuroimaging Markers In Autosomal Dominant Alzheimer Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4937  0.555
2019 Gonneaud J, Baria A, Binette AP, Benzinger TLS, Morris JC, Bateman R, Breitner JCS, Poirier J, Vachon-Presseau E, Villeneuve S. Ic-P-054: Prediction Of Brain Age Using Resting-State Functional Connectivity Reveals Accelerated Aging In The Preclinical Phase Of Autosomal Dominant Alzheimer'S Disease, Irrespectiveof Amyloid Pathology Alzheimers & Dementia. 15: 240. DOI: 10.1016/J.Jalz.2019.06.4897  0.444
2019 Schultz SA, Adedokun A, Strain JF, Wang Q, Preische O, Kuhle J, Morris JC, Bateman R, Jucker M, Gordon BA, Benzinger TLS. O3-12-01: Association Between Serum Neurofilament Light And Established White Matter Neuroimaging Markers In Autosomal Dominant Alzheimer Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4690  0.572
2019 Delmar P, Kerchner GA, Wang G, Bateman R, Klein G, Rehal S, Voyle N, Andjelkovic M, Abi-Saab D, Bullain SS, Ristic S, Baudler M, Fontoura P, Doody R. O3-10-01: CORRELATION BETWEEN AMYLOID REDUCTION AND CLINICAL OUTCOMES: EXPLORATORY ANALYSES FROM THE GANTENERUMAB SCARLET ROAD AND MARGUERITE ROAD OPEN-LABEL EXTENSION STUDIES Alzheimer's & Dementia. 15: P908-P909. DOI: 10.1016/J.Jalz.2019.06.4678  0.307
2019 Wang G, Aschenbrenner AJ, Li Y, Mcdade E, Liu L, Benzinger TLS, Bateman R, Morris JC, Hassenstab J, Berry S, Xiong C. Two-Period Linear Mixed Effects Primary Analysis Model For Clinical Trials With Run-In Data For Alzheimer Disease Alzheimers & Dementia. 15: 217. DOI: 10.1016/J.Jalz.2019.06.4566  0.378
2019 Wang G, Lorenzi M, Li Y, Donohue MC, Mcdade E, Aschenbrenner AJ, Benzinger TL, Fagan AM, Schindler SE, Hassenstab J, Berry S, Morris JC, Xiong C, Bateman R. ESTIMATING YEARS FROM CLINICAL SYMPTOM ONSET FOR SPORADIC ALZHEIMER DISEASE: HOW FAR ARE WE? Alzheimer's & Dementia. 15: P216-P217. DOI: 10.1016/J.Jalz.2019.06.4565  0.392
2019 Li Y, Schindler SE, Llibre Guerra JJ, Bollinger JG, Ovod V, Mawuenyega KG, Gordon BA, Holtzman DM, Morris JC, Benzinger TL, Xiong C, Fagan AM, Bateman R. PLASMA Aβ42/Aβ40 PREDICTS HIPPOCAMPAL ATROPHY Alzheimer's & Dementia. 15: P191-P192. DOI: 10.1016/J.Jalz.2019.06.4519  0.659
2019 Barthelemy NR, Mallipeddi N, Sato C, Bateman R. TAU PHOSPHORYLATION RATES CHANGE FROM BRAIN TO CEREBROSPINAL FLUID AND ARE DIFFERENTIALLY AFFECTED BY ALZHEIMER DISEASE Alzheimer's & Dementia. 15: P191. DOI: 10.1016/J.Jalz.2019.06.4518  0.668
2019 Vermunt L, Tijms BM, Visser PJ, Scheltens P, Bateman R, Benzinger TLS, Gordon BA, Dian. O2-09-04: Single-Subject Grey Matter Networks Deteriorate 12 Years Before Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4502  0.497
2019 Montal V, Vilaplana E, Pegueroles J, Alcolea D, Levin J, Benzinger TLS, Bateman R, Clarimon J, Blesa R, Lleó A, Sanchez-Valle R, Fortea J. O2-09-02: Biphasic Trajectory Of Changes For Cortical Thickness And Cortical Mean Diffusivity In Autosomal-Dominant Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4500  0.358
2019 Barthelemy NR, Liu H, Bateman R, Lucey BP. F2-08-03: EFFECT OF SLEEP ON CSF TAU AND P-TAU Alzheimer's & Dementia. 15: P529-P530. DOI: 10.1016/J.Jalz.2019.06.4446  0.33
2019 Bateman R, Schindler SE, Bollinger JG, Ovod V, Mawuenyega KG, Li Y, Gordon BA, Holtzman DM, Morris JC, Benzinger TL, Xiong C, Fagan AM. F2-07-01: BLOOD AMYLOID-BETA PREDICTS AMYLOID PET CONVERSION Alzheimer's & Dementia. 15: P526-P526. DOI: 10.1016/J.Jalz.2019.06.4440  0.545
2019 Joseph-Mathurin N, Perrin RJ, Cairns NJ, Franklin EE, Xiong C, Preboske GM, Jack CR, Morris JC, Bateman R, Benzinger TLS. Ic-P-046: Cerebral Amyloid Angiopathy Is More Severe In Autosomal Dominant Ad Cases With Cerebral Microhemorrhages: Results From The Dian Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4208  0.632
2019 Barthelemy NR, Liu H, Bateman R, Lucey BP. P4-066: EFFECT OF SLEEP ON CSF TAU AND P-TAU Alzheimer's & Dementia. 15: P1298-P1298. DOI: 10.1016/J.Jalz.2019.06.3726  0.332
2019 Flores S, Su Y, Gordon BA, Adedokun A, Marple LM, Wang Q, Chen G, Hornbeck RC, Jack CR, Roberson ED, Soucy J, Noto RB, Brooks WS, Jiménez-Velázquez IZ, Gauthier S, ... ... Bateman R, et al. P3-426: REGIONAL AND VOXEL-WISE SPATIAL RELATIONSHIPS AMONG FLUORINE-18 AMYLOID PET TRACERS AND PITTSBURGH COMPOUND B Alzheimer's & Dementia. 15: P1122-P1122. DOI: 10.1016/J.Jalz.2019.06.3460  0.514
2019 Ringman JM, Coppola G, Joe EB, Bateman R, Morris JC, Benzinger TL, Chui HC. P3-182: AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE ARISING FROM A NOVEL TRUNCATION MUTATION IN PSEN1 Alzheimer's & Dementia. 15: P1000-P1000. DOI: 10.1016/J.Jalz.2019.06.3211  0.43
2019 Luckett PH, McCullough AA, McCarthy JE, Hassenstab J, Mcdade E, Bateman R, Benzinger TLS, Ances BM. Ic-P-084: Predicting Metabolic And Structural Changes In Dominantly Inherited Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2492  0.39
2019 Florian H, Arnold SE, Bateman R, Braunstein JB, Budur K, Kerwin DR, Soares H, Wang D, Holtzman DM. ABBV-8E12, A HUMANIZED ANTI-TAU MONOCLONAL ANTIBODY, FOR TREATING EARLY ALZHEIMER’S DISEASE: UPDATED DESIGN AND BASELINE CHARACTERISTICS OF A PHASE 2 STUDY Alzheimer's & Dementia. 15: P251-P252. DOI: 10.1016/J.Jalz.2019.06.075  0.482
2018 Wang G, Xiong C, McDade EM, Hassenstab J, Aschenbrenner AJ, Fagan AM, Benzinger TLS, Gordon BA, Morris JC, Li Y, Bateman RJ. Simultaneously evaluating the effect of baseline levels and longitudinal changes in disease biomarkers on cognition in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 4: 669-676. PMID 30569014 DOI: 10.1016/J.Trci.2018.10.009  0.624
2018 Self WK, Schoch KM, Alex J, Barthélemy N, Bollinger JG, Sato C, Cole T, Kordasiewicz HB, Swayze E, Bateman RJ, Miller TM. Protein production is an early biomarker for RNA-targeted therapies. Annals of Clinical and Translational Neurology. 5: 1492-1504. PMID 30564616 DOI: 10.1002/Acn3.657  0.511
2018 Bussy A, Snider BJ, Coble D, Xiong C, Fagan AM, Cruchaga C, Benzinger TLS, Gordon BA, Hassenstab J, Bateman RJ, Morris JC. Effect of apolipoprotein E4 on clinical, neuroimaging, and biomarker measures in noncarrier participants in the Dominantly Inherited Alzheimer Network. Neurobiology of Aging. 75: 42-50. PMID 30530186 DOI: 10.1016/J.Neurobiolaging.2018.10.011  0.639
2018 Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. Embo Molecular Medicine. PMID 30482868 DOI: 10.15252/Emmm.201809712  0.495
2018 Twohig D, Rodriguez-Vieitez E, Sando SB, Berge G, Lauridsen C, Møller I, Grøntvedt GR, Bråthen G, Patra K, Bu G, Benzinger TLS, Karch CM, Fagan A, Morris JC, Bateman RJ, et al. The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer's disease. Acta Neuropathologica Communications. 6: 130. PMID 30477568 DOI: 10.1186/S40478-018-0624-Z  0.457
2018 Joseph-Mathurin N, Su Y, Blazey TM, Jasielec M, Vlassenko A, Friedrichsen K, Gordon BA, Hornbeck RC, Cash L, Ances BM, Veale T, Cash DM, Brickman AM, Buckles V, Cairns NJ, ... ... Bateman RJ, et al. Utility of perfusion PET measures to assess neuronal injury in Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 10: 669-677. PMID 30417072 DOI: 10.1016/J.Dadm.2018.08.012  0.485
2018 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Fox NN, Graff-Radford NR, Levin J, Danek A, ... ... Bateman RJ, et al. Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30266303 DOI: 10.1016/J.Jalz.2018.06.3059  0.417
2018 Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, et al. White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30239611 DOI: 10.1093/Brain/Awy229  0.344
2018 McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, ... ... Bateman RJ, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/Wnl.0000000000006277  0.691
2018 Karch CM, Hernández D, Wang JC, Marsh J, Hewitt AW, Hsu S, Norton J, Levitch D, Donahue T, Sigurdson W, Ghetti B, Farlow M, Chhatwal J, Berman S, Cruchaga C, ... ... Bateman RJ, et al. Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. Alzheimer's Research & Therapy. 10: 69. PMID 30045758 DOI: 10.1186/S13195-018-0400-0  0.349
2018 Hsu S, Gordon BA, Hornbeck R, Norton JB, Levitch D, Louden A, Ziegemeier E, Laforce R, Chhatwal J, Day GS, McDade E, Morris JC, Fagan AM, Benzinger TLS, Goate AM, ... ... Bateman RJ, et al. Discovery and validation of autosomal dominant Alzheimer's disease mutations. Alzheimer's Research & Therapy. 10: 67. PMID 30021643 DOI: 10.1186/S13195-018-0392-9  0.647
2018 Lim YY, Hassenstab J, Goate A, Fagan AM, Benzinger TLS, Cruchaga C, McDade E, Chhatwal J, Levin J, Farlow MR, Graff-Radford NR, Laske C, Masters CL, Salloway S, Schofield P, ... ... Bateman RJ, et al. Effect of BDNFVal66Met on disease markers in dominantly inherited AD. Annals of Neurology. PMID 30014553 DOI: 10.1002/Ana.25299  0.437
2018 Li Z, Del-Aguila JL, Dube U, Budde J, Martinez R, Black K, Xiao Q, Cairns NJ, Dougherty JD, Lee JM, Morris JC, Bateman RJ, Karch CM, Cruchaga C, et al. Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure. Genome Medicine. 10: 43. PMID 29880032 DOI: 10.1186/S13073-018-0551-4  0.389
2018 Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, ... ... Bateman RJ, et al. Tau Kinetics in Neurons and the Human Central Nervous System. Neuron. 98: 861-864. PMID 29772204 DOI: 10.1016/J.Neuron.2018.04.035  0.619
2018 Wang G, Berry S, Xiong C, Hassenstab J, Quintana M, McDade EM, Delmar P, Vestrucci M, Sethuraman G, Bateman RJ. A novel cognitive disease progression model for clinical trials in autosomal-dominant Alzheimer's disease. Statistics in Medicine. PMID 29761523 DOI: 10.1002/Sim.7811  0.309
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Bateman RJ, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/Journal.Pone.0195838  0.579
2018 Wildburger NC, Gyngard F, Guillermier C, Patterson BW, Elbert D, Mawuenyega KG, Schneider T, Green K, Roth R, Schmidt RE, Cairns NJ, Benzinger TLS, Steinhauser ML, Bateman RJ. Amyloid-β Plaques in Clinical Alzheimer's Disease Brain Incorporate Stable Isotope Tracerand Exhibit Nanoscale Heterogeneity. Frontiers in Neurology. 9: 169. PMID 29623063 DOI: 10.3389/Fneur.2018.00169  0.821
2018 Oxtoby NP, Young AL, Cash DM, Benzinger TLS, Fagan AM, Morris JC, Bateman RJ, Fox NC, Schott JM, Alexander DC. Data-driven models of dominantly-inherited Alzheimer's disease progression. Brain : a Journal of Neurology. PMID 29579160 DOI: 10.1093/Brain/Awy050  0.368
2018 Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Jockel-Balsarotti J, Sullivan M, Crisp MJ, Kasten T, Kirmess KM, Kanaan NM, Yarasheski KE, Baker-Nigh A, Benzinger TLS, Miller TM, ... ... Bateman RJ, et al. Tau Kinetics in Neurons and the Human Central Nervous System. Neuron. 97: 1284-1298.e7. PMID 29566794 DOI: 10.1016/J.Neuron.2018.02.015  0.69
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, ... ... Bateman R, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053  0.482
2018 Villeneuve S, Vogel JW, Gonneaud J, Pichet Binette A, Rosa-Neto P, Gauthier S, Bateman RJ, Fagan AM, Morris JC, Benzinger TLS, Johnson SC, Breitner JCS, Poirier J. Proximity to Parental Symptom Onset and Amyloid-β Burden in Sporadic Alzheimer Disease. Jama Neurology. PMID 29482212 DOI: 10.1001/Jamaneurol.2017.5135  0.387
2018 Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Bateman RJ, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/Brain/Awy008  0.389
2018 McDade E, Bateman RJ. Tau Positron Emission Tomography in Autosomal Dominant Alzheimer Disease: Small Windows, Big Picture. Jama Neurology. 75: 536-538. PMID 29435570 DOI: 10.1001/jamaneurol.2017.4026  0.343
2018 Gordon BA, Blazey TM, Su Y, Hari-Raj A, Dincer A, Flores S, Christensen J, McDade E, Wang G, Xiong C, Cairns NJ, Hassenstab J, Marcus DS, Fagan AM, Jack CR, ... ... Bateman RJ, et al. Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer's disease: a longitudinal study. The Lancet. Neurology. PMID 29397305 DOI: 10.1016/S1474-4422(18)30028-0  0.698
2017 Xiong C, Luo J, Chen L, Gao F, Liu J, Wang G, Bateman R, Morris JC. Estimating diagnostic accuracy for clustered ordinal diagnostic groups in the three-class case-Application to the early diagnosis of Alzheimer disease. Statistical Methods in Medical Research. 962280217742539. PMID 29182052 DOI: 10.1177/0962280217742539  0.354
2017 West T, Hu Y, Verghese PB, Bateman RJ, Braunstein JB, Fogelman I, Budur K, Florian H, Mendonca N, Holtzman DM. Preclinical and Clinical Development of ABBV-8E12, a Humanized Anti-Tau Antibody, for Treatment of Alzheimer's Disease and Other Tauopathies. The Journal of Prevention of Alzheimer's Disease. 4: 236-241. PMID 29181488 DOI: 10.14283/jpad.2017.36  0.766
2017 Yoon H, Belmonte KC, Kasten T, Bateman R, Kim J. Intra- and Inter-individual Variability of microRNA Levels in Human Cerebrospinal Fluid: Critical Implications for Biomarker Discovery. Scientific Reports. 7: 12720. PMID 28983117 DOI: 10.1038/S41598-017-13031-W  0.517
2017 Cruchaga C, Del-Aguila JL, Saef B, Black K, Fernandez MV, Budde J, Ibanez L, Kapoor M, Tosto G, Mayeux RP, Holtzman DM, Fagan AM, Morris JC, Bateman RJ, Goate AM, et al. Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28943286 DOI: 10.1016/J.Jalz.2017.08.013  0.55
2017 Wildburger NC, Esparza TJ, LeDuc RD, Fellers RT, Thomas PM, Cairns NJ, Kelleher NL, Bateman RJ, Brody DL. Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. Scientific Reports. 7: 9520. PMID 28842697 DOI: 10.1038/S41598-017-10422-X  0.814
2017 Ringman JM, Casado M, Van Berlo V, Pa J, Joseph-Mathurin N, Fagan AM, Benzinger T, Bateman RJ, Morris JC. A novel PSEN1 (S230N) mutation causing early-onset Alzheimer's Disease associated with prosopagnosia, hoarding, and Parkinsonism. Neuroscience Letters. 657: 11-15. PMID 28764909 DOI: 10.1016/J.Neulet.2017.07.046  0.421
2017 Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/J.Jalz.2017.06.2268  0.378
2017 Ovod V, Ramsey KN, Mawuenyega KG, Bollinger JG, Hicks T, Schneider T, Sullivan M, Paumier K, Holtzman DM, Morris JC, Benzinger T, Fagan AM, Patterson BW, Bateman RJ. Amyloid β concentrations and stable isotope labeling kinetics of human plasma specific to central nervous system amyloidosis. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28734653 DOI: 10.1016/J.Jalz.2017.06.2266  0.501
2017 McDade E, Bateman RJ. Stop Alzheimer's before it starts. Nature. 547: 153-155. PMID 28703214 DOI: 10.1038/547153a  0.372
2017 Brown BM, Sohrabi HR, Taddei K, Gardener SL, Rainey-Smith SR, Peiffer JJ, Xiong C, Fagan AM, Benzinger T, Buckles V, Erickson KI, Clarnette R, Shah T, Masters CL, Weiner M, ... ... Bateman RJ, et al. Habitual exercise levels are associated with cerebral amyloid load in presymptomatic autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28501451 DOI: 10.1016/J.Jalz.2017.03.008  0.394
2017 Lucey BP, Fagan AM, Holtzman DM, Morris JC, Bateman RJ. Diurnal oscillation of CSF Aβ and other AD biomarkers. Molecular Neurodegeneration. 12: 36. PMID 28478762 DOI: 10.1186/S13024-017-0161-4  0.604
2017 Schoenfeld HA, West T, Verghese PB, Holubasch M, Shenoy N, Kagan D, Buono C, Zhou W, DeCristofaro M, Douville J, Goodrich GG, Mansfield K, Saravanan C, Cumin F, Webb RL, ... Bateman RJ, et al. The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey. Toxicology and Applied Pharmacology. PMID 28315356 DOI: 10.1016/J.Taap.2017.03.014  0.797
2017 Ovod V, Bollinger JG, Mawuenyega KG, Hicks TJ, Schneider T, Kasten T, Sigurdson W, Sullivan M, Donahue TA, Ramsey K, Paumier KL, Holtzman DM, Morris JC, Benzinger TL, Fagan AM, ... ... Bateman RJ, et al. CONCENTRATIONS AND STABLE ISOTOPE LABEL KINETICS OF HUMAN PLASMA AMYLOID BETA Alzheimer's & Dementia. 13: P1475-P1476. DOI: 10.1016/J.Jalz.2017.08.005  0.396
2017 McDade E, Wang G, Benzinger TL, Buckles VD, Fagan AM, Gordon BA, Hassenstab J, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier KL, Xiong C, Ricardo A, ... ... Bateman RJ, et al. LONGITUDINAL BIOMARKER CHANGES IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE FROM THE DIAN STUDY Alzheimer's & Dementia. 13: P879-P880. DOI: 10.1016/J.Jalz.2017.07.265  0.677
2017 Barthélemy NR, Gabelle A, Sato C, Lehmann S, Bateman RJ. [P2-258]: HIGHLY SPECIFIC CSF TAU HYPERPHOSPHORYLATION ON T217 OCCURS SIMULTANEOUSLY WITH AMYLOIDOSIS Alzheimer's & Dementia. 13: P712-P712. DOI: 10.1016/J.Jalz.2017.06.911  0.537
2017 Xiong C, Wang G, Coble D, Fague S, Fagan AM, Benzinger TL, Hassenstab J, Buckles V, Moulder KL, Paumier KL, Morris JC, Bateman RJ. [P2-209]: QUANTIFYING PRECLINICAL STAGES OF AUTOSOMAL DOMINANT ALZHEIMER DISEASE (ADAD) AND THE ASSOCIATED OVERALL BIOMARKER SIGNATURE ACROSS MODALITIES USING THE DOMINANTLY INHERITED ALZHEIMER NETWORK (DIAN) Alzheimer's & Dementia. 13: P689-P690. DOI: 10.1016/J.Jalz.2017.06.861  0.378
2017 Vlassenko AG, Gordon BA, Goyal MS, Su Y, Durbin TJ, Couture LE, Holtzman DM, Morris JC, Fagan AM, Benzinger TL, Bateman RJ, Raichle ME. [IC-P-064]: BRAIN AEROBIC GLYCOLYSIS AND AD PATHOLOGY BIOMARKERS IN AUTOSOMAL DOMINANT AD Alzheimer's & Dementia. 13: P53-P53. DOI: 10.1016/J.Jalz.2017.06.2337  0.659
2016 Ghosal K, Haag M, Verghese PB, West T, Veenstra T, Braunstein JB, Bateman RJ, Holtzman DM, Landreth GE. A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects. Alzheimer's & Dementia (New York, N. Y.). 2: 110-120. PMID 29067298 DOI: 10.1016/J.Trci.2016.06.001  0.788
2016 Suárez-Calvet M, Araque Caballero MÁ, Kleinberger G, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Ewers M, Haass C. Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury. Science Translational Medicine. 8: 369ra178. PMID 27974666 DOI: 10.1126/Scitranslmed.Aag1767  0.404
2016 Esparza TJ, Wildburger NC, Jiang H, Gangolli M, Cairns NJ, Bateman RJ, Brody DL. Soluble Amyloid-beta Aggregates from Human Alzheimer's Disease Brains. Scientific Reports. 6: 38187. PMID 27917876 DOI: 10.1038/srep38187  0.805
2016 Baker-Nigh AT, Mawuenyega KG, Bollinger JG, Ovod V, Kasten T, Franklin EE, Liao F, Jiang H, Holtzman D, Cairns NJ, Morris JC, Bateman RJ. Human Central Nervous System (CNS) ApoE Isoforms are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared to Plasma. The Journal of Biological Chemistry. PMID 27793990 DOI: 10.1074/Jbc.M116.721779  0.531
2016 Natelson Love M, Clark DG, Cochran JN, Den Beste KA, Geldmacher DS, Benzinger TL, Gordon BA, Morris JC, Bateman RJ, Roberson ED. Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease. Neurobiology of Aging. PMID 27793474 DOI: 10.1016/J.Neurobiolaging.2016.09.020  0.585
2016 Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, ... ... Bateman RJ, et al. Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). The Lancet. Neurology. PMID 27777020 DOI: 10.1016/S1474-4422(16)30229-0  0.328
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Bateman RJ, et al. Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0163669. PMID 27649320 DOI: 10.1371/journal.pone.0163669  0.32
2016 Bateman RJ, Benzinger TL, Berry S, Clifford DB, Duggan C, Fagan AM, Fanning K, Farlow MR, Hassenstab J, McDade EM, Mills S, Paumier K, Quintana M, Salloway SP, Santacruz A, et al. The DIAN-TU Next Generation Alzheimer's prevention trial: Adaptive design and disease progression model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27583651 DOI: 10.1016/J.Jalz.2016.07.005  0.303
2016 Lim YY, Hassenstab J, Cruchaga C, Goate A, Fagan AM, Benzinger TL, Maruff P, Snyder PJ, Masters CL, Allegri R, Chhatwal J, Farlow MR, Graff-Radford NR, Laske C, Levin J, ... ... Bateman RJ, et al. BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 27521573 DOI: 10.1093/Brain/Aww200  0.588
2016 Muenchhoff J, Poljak A, Thalamuthu A, Gupta VB, Chatterjee P, Raftery M, Masters CL, Morris JC, Bateman RJ, Fagan AM, Martins RN, Sachdev PS. Changes in the plasma proteome at asymptomatic and symptomatic stages of autosomal dominant Alzheimer's disease. Scientific Reports. 6: 29078. PMID 27381087 DOI: 10.1038/Srep29078  0.301
2016 Weninger S, Carrillo MC, Dunn B, Aisen PS, Bateman RJ, Kotz JD, Langbaum JB, Mills SL, Reiman EM, Sperling R, Santacruz AM, Tariot PN, Welsh-Bohmer KA. Collaboration for Alzheimer's Prevention: Principles to guide data and sample sharing in preclinical Alzheimer's disease trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 12: 631-2. PMID 27157073 DOI: 10.1016/J.Jalz.2016.04.001  0.367
2016 Hendrix JA, Bateman RJ, Brashear HR, Duggan C, Carrillo MC, Bain LJ, DeMattos R, Katz RG, Ostrowitzki S, Siemers E, Sperling R, Vitolo OV. Challenges, solutions, and recommendations for Alzheimer's disease combination therapy. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27017906 DOI: 10.1016/J.Jalz.2016.02.007  0.313
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, ... ... Bateman RJ, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1002/ana.24647  0.57
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Bateman RJ, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/Journal.Pone.0152082  0.384
2016 Hölttä M, Dean RA, Siemers E, Mawuenyega KG, Sigurdson W, May PC, Holtzman DM, Portelius E, Zetterberg H, Bateman RJ, Blennow K, Gobom J. A single dose of the γ-secretase inhibitor semagacestat alters the cerebrospinal fluid peptidome in humans. Alzheimer's Research & Therapy. 8: 11. PMID 26948580 DOI: 10.1186/S13195-016-0178-X  0.522
2016 Chatterjee P, Lim WL, Shui G, Gupta VB, James I, Fagan AM, Xiong C, Sohrabi HR, Taddei K, Brown BM, Benzinger T, Masters C, Snowden SG, Wenk MR, Bateman RJ, et al. Plasma Phospholipid and Sphingolipid Alterations in Presenilin1 Mutation Carriers: A Pilot Study. Journal of Alzheimer's Disease : Jad. PMID 26836186 DOI: 10.3233/Jad-150948  0.339
2016 Ghosal K, Haag M, Verghese PB, West T, Veenstra T, Braunstein JB, Bateman RJ, Holtzman DM, Landreth GE. A randomized controlled study to evaluate the effect of bexarotene on amyloid-β and apolipoprotein E metabolism in healthy subjects Alzheimer's and Dementia: Translational Research and Clinical Interventions. 2: 110-120. DOI: 10.1016/j.trci.2016.06.001  0.801
2016 Petros J, Hassenstab J, Snitz BE, Zhou Y, Ringman JM, McDade E, Wang G, Balota DA, Aschenbrenner AJ, Benzinger TL, Cruchaga C, Fagan AM, Goate AM, Holtzman DM, Buckles V, ... ... Bateman R, et al. Dynamic Relationships Between “Big Five” Personality Traits, Alzheimer’S Disease Biomarkers, And Cognition In Autosomal Dominant Alzheimer’S Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.970  0.514
2016 Wildburger NC, Esparza TJ, Cairns NJ, Bateman R, Brody DL. P1-100: Amyloid-Beta (Aβ) Isoforms and Ptms of Soluble Aβ Oligomers from Human Brain Alzheimer's & Dementia. 12: P439-P440. DOI: 10.1016/J.Jalz.2016.06.848  0.791
2016 Zhou Y, Bateman R, Hassenstab J, Snitz BE, Masters CL, Danek A, Laske C, Farlow MR, Ringman JM. Personality Characteristics And Alterations In Familial Alzheimer’S Disease In The Dominantly Inherited Alzheimer Network (Dian) Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.711  0.397
2016 McDade E, Weng H, Wang G, Xiong C, Fagan AM, Hassenstab J, Marcus DS, Morris JC, Benzinger TL, Cairns NJ, Goate AM, Buckles V, Holtzman DM, Berman S, Ghetti B, ... ... Bateman R, et al. O5-02-01: Longitudinal Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease: The Dominantly Inherited Alzheimer Network Alzheimer's & Dementia. 12: P378-P379. DOI: 10.1016/J.Jalz.2016.06.710  0.594
2016 Benzinger TLS, Gordon BA, Friedrichsen KA, Su Y, Christensen J, Hornbeck RC, Mishra S, Aldea P, Cash L, Ances B, McConathy J, Koeppe RA, McDade E, Cairns NJ, Morris JC, ... Bateman R, et al. Tau Pet Imaging With Av-1451 In Autosomal Dominant Alzheimer'S Disease: Update From The Dominantly Inherited Alzheimer Network (Dian) Alzheimers & Dementia. 12: 378. DOI: 10.1016/J.Jalz.2016.06.709  0.659
2016 Lim YY, Hassenstab J, Cruchaga C, Goate AM, Fagan AM, Lee Smith Benzinger T, Maruff P, Snyder PJ, Masters CL, Ricardo A, Chhatwal JP, Farlow MR, Graff-Radford NR, Laske C, Levin J, ... ... Bateman R, et al. F5-02-03: BDNF VAL66MET Moderates Cognitive Impairment, Neuronal Dysfunction and TAU in Preclinical Autosomal Dominant Alzheimer's Disease Alzheimer's & Dementia. 12: P369-P369. DOI: 10.1016/J.Jalz.2016.06.689  0.568
2016 Cash DM, Kinnunen KM, Weston PS, Ryan NS, Modat M, Bateman R, Morris JC, Ourselin S, Rossor MN, Benzinger TLS, Fox NC. Longitudinal Atrophy In Autosomal Dominant Ad And Sporadic Ad: Lessons From Dian Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.688  0.464
2016 Bateman R, Lee Smith Benzinger T, Berry S, Clifford D, Fagan AM, Duggan C, Fanning K, Goate AM, Hassenstab J, McDade E, Mills S, Morris JC, Salloway S, Farlow MR, Santacruz A, et al. F4-03-02: The Dominantly Inherited Alzheimer Network Trials Unit Alzheimer's & Dementia. 12: P326-P326. DOI: 10.1016/J.Jalz.2016.06.597  0.314
2016 Weninger S, Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman R, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo M. F4-03-01: Collaboration for Alzheimer's Prevention (CAP): Advancing the Evaluation of Preclinical Alzheimer's Disease Treatments Alzheimer's & Dementia. 12: P325-P326. DOI: 10.1016/J.Jalz.2016.06.596  0.463
2016 Joseph-Mathurin N, Vlassenko AG, Fagan AM, Su Y, Friedrichsen KA, Owen CJ, Gordon BA, Hornbeck RC, Koeppe RA, Xiong C, Morris JC, Bateman R, Benzinger TL. Neuronal Injury And Degeneration Evaluated With Imaging And Csf Biomarkers In Autosomal Dominant Alzheimer'S Disease: Results From The Dian Study Alzheimers & Dementia. 12: 246. DOI: 10.1016/J.Jalz.2016.06.440  0.594
2016 Lee S, Zimmerman ME, Viqar F, Narkhede A, Tosto G, Lee Smith Benzinger T, Marcus DS, Goate AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, Martins RN, ... ... Bateman R, et al. O2-03-02: are White Matter Hyperintensities a Core Feature of Alzheimer’s Disease or Just a Reflection of Amyloid Angiopathy? Evidence From the Dominantly Inherited Alzheimer Network (DIAN) Alzheimer's & Dementia. 12: P226-P226. DOI: 10.1016/J.Jalz.2016.06.406  0.565
2016 Laske C, Preische O, Graeber S, Jucker M, Bateman R, Morris JC, Mueller S. Decreased Body Mass Index In The Preclinical Stage Of Alzheimer'S Disease: Evidence From The Dominantly Inherited Alzheimer Network Alzheimers & Dementia. 12: 1069. DOI: 10.1016/J.Jalz.2016.06.2236  0.451
2016 Cash DM, Ridgway GR, Kinnunen KM, Benzinger TLS, Wallon D, Jack CR, Bateman R, Morris JC, Rossor MN, Ourselin S, Fox NC. A Longitudinal Morphometric Study Of Familial Alzheimer’S Disease: Results From Dian Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.172  0.409
2016 Joseph-Mathurin N, Vlassenko AG, Fagan AM, Su Y, Friedrichsen KA, Owen CJ, Gordon BA, Hornbeck RC, Koeppe RA, Xiong C, Morris JC, Bateman R, Benzinger TL. Neuronal Injury And Degeneration Evaluated With Imaging And Csf Biomarkers In Autosomal Dominant Ad: Results From The Dian Study Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.147  0.564
2015 Masters CL, Bateman R, Blennow K, Rowe CC, Sperling RA, Cummings JL. Alzheimer's disease. Nature Reviews. Disease Primers. 1: 15056. PMID 27188934 DOI: 10.1038/nrdp.2015.56  0.419
2015 Ringman JM, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, ... ... Bateman R, et al. Erratum: Early behavioural changes in familial Alzheimers disease in the Dominantly Inherited Alzheimer Network (Brain (2015) 138 (103645) (10.1093/brain/awv004)) Brain. 138. PMID 26598496 DOI: 10.1093/Brain/Awv210  0.452
2015 Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/Nrneurol.2015.177  0.387
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, ... ... Bateman RJ, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/Wnl.0000000000001903  0.529
2015 Patterson BW, Elbert DL, Mawuenyega KG, Kasten T, Ovod V, Ma S, Xiong C, Chott R, Yarasheski K, Sigurdson W, Zhang L, Goate A, Benzinger T, Morris JC, Holtzman D, ... Bateman RJ, et al. Age and amyloid effects on human CNS amyloid-beta kinetics. Annals of Neurology. PMID 26040676 DOI: 10.1002/Ana.24454  0.522
2015 Cairns NJ, Perrin RJ, Franklin EE, Carter D, Vincent B, Xie M, Bateman RJ, Benzinger T, Friedrichsen K, Brooks WS, Halliday GM, McLean C, Ghetti B, Morris JC, et al. Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN). Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 25964057 DOI: 10.1111/Neup.12205  0.678
2015 Ringman JM, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, ... ... Bateman R, et al. Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network. Brain : a Journal of Neurology. 138: 1036-45. PMID 25688083 DOI: 10.1093/Brain/Awv004  0.383
2015 Chatterjee P, Gupta VB, Fagan AM, Jasielec MS, Xiong C, Sohrabi HR, Dhaliwal S, Taddei K, Bourgeat P, Brown BM, Benzinger T, Bateman RJ, Morris JC, Martins RN. Decreased platelet APP isoform ratios in autosomal dominant Alzheimer's disease: baseline data from a DIAN cohort subset. Current Alzheimer Research. 12: 157-64. PMID 25654503 DOI: 10.2174/1567205012666150204125732  0.383
2015 Elbert DL, Patterson BW, Bateman RJ. Analysis of a compartmental model of amyloid beta production, irreversible loss and exchange in humans. Mathematical Biosciences. 261: 48-61. PMID 25497960 DOI: 10.1016/J.Mbs.2014.11.004  0.311
2015 Bateman R. Alzheimer's disease and other dementias: Advances in 2014 The Lancet Neurology. 14: 4-6. PMID 25496880 DOI: 10.1016/S1474-4422(14)70301-1  0.518
2015 Chatterjee P, Gupta VB, Fagan AM, Jasielec MS, Xiong C, Sohrabi HR, Dhaliwal S, Taddei K, Bourgeat P, Brown BM, Benzinger T, Bateman RJ, Morris JC, Martins RN. Decreased platelet APP isoform ratios in autosomal dominant Alzheimer’s disease: Baseline data from a DIAN cohort subset Current Alzheimer Research. 12: 157-164. DOI: 10.2174/1567205012666150204125732  0.315
2015 Sato C, Mawuenyega K, Barthelemy N, Patterson BW, Kasten T, Jockel-Balsarotti J, Chott R, Yarasheski KE, Miller TM, Bateman R. DT-02-04: Tau kinetics in the human cns Alzheimer's & Dementia. 11: P334-P335. DOI: 10.1016/J.Jalz.2015.08.160  0.588
2015 Barthelemy N, Hirtz C, Schraen S, Seveno M, Bateman R, Marin P, Becher F, Gabelle A, Lehmann S. Mass spectrometry follow-up of t181, s199, s202, t205, and T217 tau phosphorylation in cerebrospinal fluid from patients revealed a specific Alzheimer’s disease pattern Alzheimers & Dementia. 11: 870. DOI: 10.1016/J.Jalz.2015.08.063  0.322
2015 Hassenstab J, Lim Y, Fagan AM, Ma S, Xiong C, Buckles V, Bateman R, Morris JC. CSF tau predicts working memory and global cognitive decline in autosomal dominant Alzheimer’s disease Alzheimers & Dementia. 11: 379. DOI: 10.1016/J.Jalz.2015.06.302  0.378
2015 Brier MR, McCarthy JE, Friedrichsen K, Benzinger TL, Bateman R, Su Y, Morris JC, Ances B. P4-061: Amyloid deposition disrupts local and distant glucose metabolism Alzheimer's & Dementia. 11: P790-P790. DOI: 10.1016/J.Jalz.2015.06.1766  0.319
2015 Joseph-Mathurin N, Su Y, Vlassenko A, Couture L, Blazey T, Friedrichsen KA, Owen CJ, Hornbeck RC, Cash L, Stevenson TA, Ances B, Xiong C, Buckles V, Moulder KL, Morris JC, ... Bateman R, et al. P3-132: Comparison of cerebral glucose metabolism 18 F-FDG, early frames of 11 C-PiB, and cerebral blood flow 15 O-H2 O in autosomal dominant Alzheimer's disease Alzheimer's & Dementia. 11: P674-P674. DOI: 10.1016/J.Jalz.2015.06.1000  0.322
2015 Joseph-Mathurin N, Tang M, Friedrichsen KA, Owen CJ, Su Y, Hornbeck RC, Stevenson TA, Cash L, Raichle ME, Gordon B, Preboske GM, Koeppe RA, Jack CR, Goate A, Cruchaga C, ... ... Bateman R, et al. Amyloid load increase and cerebral microbleed prevalence differ as a function of the position of the mutation within the PSEN1 coding sequence Alzheimers & Dementia. 11: 172. DOI: 10.1016/J.Jalz.2015.06.072  0.503
2015 Joseph-Mathurin N, Su Y, Vlassenko A, Jasielec MS, Blazey T, Friedrichsen KA, Owen CJ, Hornbeck RC, Stevenson TA, Cash L, Xiong C, Ringman JM, Brickman AM, Koeppe RA, Ances B, ... ... Bateman R, et al. IC-03-02: Early frame of PiB and FDG in autosomal dominant Alzheimer's disease: Similarity, discrepancy, and clinical implication Alzheimer's & Dementia. 11: P8-P9. DOI: 10.1016/J.Jalz.2015.06.013  0.424
2015 Mattsson N, Carrillo MC, Dean RA, Devous MD, Nikolcheva T, Pesini P, Salter H, Potter WZ, Sperling RS, Bateman RJ, Bain LJ, Liu E. Revolutionizing Alzheimer's disease and clinical trials through biomarkers Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1: 412-419. DOI: 10.1016/j.dadm.2015.09.001  0.339
2014 Sheline YI, West T, Yarasheski K, Jasielec MS, Hettinger JC, Tripoli DL, Xiong C, Frederiksen C, Grzelak MV, Bateman RJ, Morris JC, Lee JM, Cirrito JR. Reply to comment on "An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice". Science Translational Medicine. 6: 268lr4. PMID 25540323 DOI: 10.1126/Scitranslmed.3010609  0.731
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/Jamaneurol.2014.1654  0.53
2014 Dobrowolska JA, Michener MS, Wu G, Patterson BW, Chott R, Ovod V, Pyatkivskyy Y, Wildsmith KR, Kasten T, Mathers P, Dancho M, Lennox C, Smith BE, Gilberto D, McLoughlin D, ... ... Bateman RJ, et al. CNS amyloid-β, soluble APP-α and -β kinetics during BACE inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8336-46. PMID 24920637 DOI: 10.1523/Jneurosci.0540-14.2014  0.352
2014 Lucey BP, Bateman RJ. Amyloid-β diurnal pattern: Possible role of sleep in Alzheimer's disease pathogenesis Neurobiology of Aging. 35. PMID 24910393 DOI: 10.1016/j.neurobiolaging.2014.03.035  0.314
2014 Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, DeKosky ST, Gauthier S, Selkoe D, Bateman R, Cappa S, Crutch S, Engelborghs S, Frisoni GB, Fox NC, et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. The Lancet. Neurology. 13: 614-29. PMID 24849862 DOI: 10.1016/S1474-4422(14)70090-0  0.536
2014 Sheline YI, West T, Yarasheski K, Swarm R, Jasielec MS, Fisher JR, Ficker WD, Yan P, Xiong C, Frederiksen C, Grzelak MV, Chott R, Bateman RJ, Morris JC, Mintun MA, et al. An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice. Science Translational Medicine. 6: 236re4. PMID 24828079 DOI: 10.1126/Scitranslmed.3008169  0.777
2014 Dobrowolska JA, Kasten T, Huang Y, Benzinger TL, Sigurdson W, Ovod V, Morris JC, Bateman RJ. Diurnal patterns of soluble amyloid precursor protein metabolites in the human central nervous system. Plos One. 9: e89998. PMID 24646516 DOI: 10.1371/Journal.Pone.0089998  0.373
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/Scitranslmed.3007901  0.614
2014 Cash DM, Kinnunen KM, Leung KK, Ahsan L, Cardoso J, Modat M, Nicholas J, Malone I, Benzinger T, Jack CR, Thompson P, Saykin AJ, Sperling RR, Villemagne V, Weiner M, ... ... Bateman R, et al. Longitudinal Rates Of Atrophy In Familial Alzheimer'S Disease Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.05.112  0.439
2014 Risacher SL, West JD, Tallman EM, McDonald BC, Wang Y, Epperson F, Murrell J, Benzinger TL, Bateman R, Morris JC, Farlow MR, Ghetti BF, Saykin AJ. IC-P-094: ALTERED FMRI ACTIVATION PATTERN DURING VISUAL SCENE ENCODING IN AFFECTED AND NON-AFFECTED CARRIERS OF PSEN1 AND APP MUTATIONS Alzheimer's & Dementia. 10: P53-P53. DOI: 10.1016/J.Jalz.2014.05.099  0.379
2014 Bateman R. PL-05-02: HUMAN METABOLISM AND KINETICS OF ALZHEIMER'S DISEASE PROTEINS Alzheimer's & Dementia. 10: P286-P286. DOI: 10.1016/J.Jalz.2014.04.475  0.44
2014 Hassenstab J, Aschenbrenner A, Balota D, Dreyfus DM, Bateman R, Morris JC. O4-12-06: COGNITIVE PERFORMANCE IN THE DOMINANTLY INHERITED ALZHEIMER NETWORK (DIAN): BASELINE AND PRELIMINARY LONGITUDINAL FINDINGS Alzheimer's & Dementia. 10: P277-P277. DOI: 10.1016/J.Jalz.2014.04.456  0.345
2014 Ryman D, Morris J, Bateman R. Predicting Symptom Onset In Autosomal Dominant Alzheimer'S Disease: A Systematic Review And Meta-Analysis Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.04.299  0.396
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/Pnas.1317918110  0.487
2013 Moulder KL, Snider BJ, Mills SL, Buckles VD, Santacruz AM, Bateman RJ, Morris JC. Dominantly Inherited Alzheimer Network: facilitating research and clinical trials. Alzheimer's Research & Therapy. 5: 48. PMID 24131566 DOI: 10.1186/Alzrt213  0.409
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, ... ... Bateman RJ, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/Wnl.0B013E3182A841C6  0.327
2013 Frost SM, Kanagasingam Y, Sohrabi HR, Taddei K, Bateman R, Morris J, Benzinger T, Goate A, Masters CL, Martins RN. Pupil response biomarkers distinguish amyloid precursor protein mutation carriers from non-carriers. Current Alzheimer Research. 10: 790-6. PMID 23919771 DOI: 10.2174/15672050113109990154  0.452
2013 Chhatwal JP, Schultz AP, Johnson K, Benzinger TL, Jack C, Ances BM, Sullivan CA, Salloway SP, Ringman JM, Koeppe RA, Marcus DS, Thompson P, Saykin AJ, Correia S, Schofield PR, ... ... Bateman R, et al. Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology. 81: 736-44. PMID 23884042 DOI: 10.1212/Wnl.0B013E3182A1Aafe  0.422
2013 Potter R, Patterson BW, Elbert DL, Ovod V, Kasten T, Sigurdson W, Mawuenyega K, Blazey T, Goate A, Chott R, Yarasheski KE, Holtzman DM, Morris JC, Benzinger TL, Bateman RJ. Increased in vivo amyloid-β42 production, exchange, and loss in presenilin mutation carriers. Science Translational Medicine. 5: 189ra77. PMID 23761040 DOI: 10.1126/Scitranslmed.3005615  0.515
2013 Mawuenyega KG, Kasten T, Sigurdson W, Bateman RJ. Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics. Analytical Biochemistry. 440: 56-62. PMID 23714261 DOI: 10.1016/j.ab.2013.04.031  0.399
2013 Esparza TJ, Zhao H, Cirrito JR, Cairns NJ, Bateman RJ, Holtzman DM, Brody DL. Amyloid-β oligomerization in Alzheimer dementia versus high-pathology controls. Annals of Neurology. 73: 104-19. PMID 23225543 DOI: 10.1002/Ana.23748  0.73
2013 Thomas J, Brier M, Bateman R, Snyder A, Benzinger T, Xiong C, Raichle M, Sperling R, Mayeux R, Ghetti B, Ringman J, Salloway S, McDade E, Rossor M, Schofield P, et al. P1-271: Resting state functional connectivity in autosomal dominant and sporadic Alzheimer's disease Alzheimer's & Dementia. 9: P252-P253. DOI: 10.1016/j.jalz.2013.05.496  0.323
2013 Thomas J, Brier M, Bateman R, Snyder A, Benzinger T, Xiong C, Raichle M, Sperling R, Mayeux R, Ghetti B, Ringman J, Salloway S, McDade E, Rossor M, Schofield P, et al. IC-P-184: Resting state functional connectivity in autosomal dominant and sporadic Alzheimer's disease Alzheimer's & Dementia. 9: P105-P105. DOI: 10.1016/J.Jalz.2013.05.181  0.393
2013 Blazey T, Jack C, Kantarci K, Preboske G, Ringman J, Brickman A, Raichle M, Hornbeck R, Saykin A, Salloway S, McDade E, Rossor M, Fox N, Thompson P, Correia S, ... ... Bateman R, et al. Prevalence and growth of cerebral microhemorrhages in autosomal dominant Alzheimer's disease Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.100  0.435
2013 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Ances B, Sullivan C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, ... ... Bateman R, et al. IC-P-082: Disrupted functional connectivity in autosomal dominant Alzheimer's disease demonstrates network specificity and precedes brain volume loss: Findings from DIAN Alzheimer's & Dementia. 9: P49-P50. DOI: 10.1016/J.Jalz.2013.05.079  0.412
2013 Cash D, Ridgway G, Modat M, Ryan N, Kinnunen K, Cardoso J, Benzinger T, Jack CR, Raichle M, Marcus D, Ringman J, Thompson P, Ghetti B, Salloway S, Sperling R, ... ... Bateman R, et al. Dissociating volume and intensity differences in familial Alzheimer's disease Alzheimers & Dementia. 9: 603. DOI: 10.1016/J.Jalz.2013.05.075  0.433
2013 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Ances B, Sullivan C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, ... ... Bateman R, et al. O4-03-03: Disrupted functional connectivity in autosomal dominant Alzheimer's disease demonstrates network specificity and precedes brain volume loss: Findings from the Dominantly Inherited Alzheimer Network Alzheimer's & Dementia. 9: P684-P685. DOI: 10.1016/J.Jalz.2013.04.348  0.431
2013 Kinnunen K, Ryan N, Cash D, Leite AB, Finnegan S, Cardoso M, Leung K, Modat M, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Ringman J, Ghetti B, ... ... Bateman R, et al. Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene-dependent? Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.017  0.407
2012 Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/Cli.12.93  0.557
2012 Roh JH, Huang Y, Bero AW, Kasten T, Stewart FR, Bateman RJ, Holtzman DM. Disruption of the sleep-wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer's disease pathology. Science Translational Medicine. 4: 150ra122. PMID 22956200 DOI: 10.1126/Scitranslmed.3004291  0.799
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/Nejmoa1202753  0.55
2012 Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, ... ... Bateman RJ, et al. In vivo human apolipoprotein E isoform fractional turnover rates in the CNS. Plos One. 7: e38013. PMID 22675504 DOI: 10.1371/Journal.Pone.0038013  0.839
2012 Hata S, Taniguchi M, Piao Y, Ikeuchi T, Fagan AM, Holtzman DM, Bateman R, Sohrabi HR, Martins RN, Gandy S, Urakami K, Suzuki T. Multiple γ-secretase product peptides are coordinately increased in concentration in the cerebrospinal fluid of a subpopulation of sporadic Alzheimer's disease subjects. Molecular Neurodegeneration. 7: 16. PMID 22534039 DOI: 10.1186/1750-1326-7-16  0.561
2012 Portelius E, Zetterberg H, Dean RA, Marcil A, Bourgeois P, Nutu M, Andreasson U, Siemers E, Mawuenyega KG, Sigurdson WC, May PC, Paul SM, Holtzman DM, Blennow K, Bateman RJ. Amyloid-β(1-15/16) as a marker for γ-secretase inhibition in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 335-41. PMID 22531418 DOI: 10.3233/Jad-2012-120508  0.499
2012 Basak JM, Kim J, Pyatkivskyy Y, Wildsmith KR, Jiang H, Parsadanian M, Patterson BW, Bateman RJ, Holtzman DM. Measurement of apolipoprotein E and amyloid β clearance rates in the mouse brain using bolus stable isotope labeling. Molecular Neurodegeneration. 7: 14. PMID 22512932 DOI: 10.1186/1750-1326-7-14  0.81
2012 Vellas B, Hampel H, Rougé-Bugat ME, Grundman M, Andrieu S, Abu-Shakra S, Bateman R, Berman R, Black R, Carrillo M, Donohue M, Mintun M, Morris J, Petersen R, Thomas RG, et al. Alzheimer's disease therapeutic trials: EU/US Task Force report on recruitment, retention, and methodology. The Journal of Nutrition, Health & Aging. 16: 339-45. PMID 22499454 DOI: 10.1007/S12603-012-0044-X  0.436
2012 Huang Y, Potter R, Sigurdson W, Santacruz A, Shih S, Ju YE, Kasten T, Morris JC, Mintun M, Duntley S, Bateman RJ. Effects of age and amyloid deposition on Aβ dynamics in the human central nervous system. Archives of Neurology. 69: 51-8. PMID 21911660 DOI: 10.1001/Archneurol.2011.235  0.443
2012 Wildsmith KR, Basak JM, Patterson BW, Pyatkivskyy Y, Kim J, Yarasheski KE, Wang JX, Mawuenyega KG, Jiang H, Parsadanian M, Yoon H, Kasten T, Sigurdson WC, Xiong C, Goate A, ... ... Bateman RJ, et al. Correction: In Vivo Human Apolipoprotein E Isoform Fractional Turnover Rates in the CNS Plos One. 7. DOI: 10.1371/Annotation/9Bd329B7-Cdea-45Ec-A4Aa-A173855Dc0B9  0.761
2012 Brody D, Esparza T, Zhao H, Cirrito J, Cairns N, Bateman R, Holtzman D. P4-266: BETA-AMYLOID oligomerization in Alzheimer's DISEASE DEMENTIA versus high pathology controls Alzheimer's & Dementia. 8: S752-S752. DOI: 10.1016/J.Jalz.2013.08.047  0.755
2012 Becker J, Koeppe R, Benzinger T, Jack C, Marcus D, Raichle M, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, Brickman A, Ghetti B, Masters C, ... ... Bateman R, et al. FDG metabolism in the DIAN study of autosomal dominant Alzheimer's disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.655  0.456
2012 Chhatwal J, Schultz A, Johnson K, Benzinger T, Jack C, Salloway S, Ringman J, Koeppe R, Marcus D, Thompson P, Saykin A, Correia S, Schofield P, Rowe C, Fox N, ... ... Bateman R, et al. O2-06-01: Disrupted functional connectivity in autosomal dominant Alzheimer's disease: Preliminary findings from the DIAN study Alzheimer's & Dementia. 8: P244-P245. DOI: 10.1016/J.Jalz.2012.05.654  0.427
2012 Huang Y, Bateman R. F2-03-04: Circadian patterns of beta-amyloid in human cerebrospinal fluid and plasma Alzheimer's & Dementia. 8: P234-P234. DOI: 10.1016/J.Jalz.2012.05.619  0.314
2012 Benzinger T, Blazey T, Ances B, Raichle M, Ances B, Snyder A, Su Y, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... ... Bateman R, et al. IC-P-128: Progressive white matter abnormalities in autosomal dominant Alzheimer's disease: Results of the DIAN study Alzheimer's & Dementia. 8: P68-P69. DOI: 10.1016/j.jalz.2012.05.1858  0.417
2012 Kinnunen K, Cash D, Leung K, Liang Y, Cardoso M, Modat M, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, ... ... Bateman R, et al. Brain and hippocampal rates of atrophy in familial Alzheimer's disease mutation carriers: Preliminary findings from the DIAN study Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.172  0.441
2012 Benzinger T, Blazey T, Koeppe R, Jack C, Raichle M, Su Y, Snyder A, Marcus D, Ringman J, Thompson P, Ghetti B, Saykin A, Salloway S, Correia S, Johnson K, ... ... Bateman R, et al. Elevated PiB precedes dementia in autosomal dominant Alzheimer's disease: PiB, FDG and atrophy in the DIAN cohort Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.132  0.521
2012 Bateman R, Morris J. F3-04-02: The dominantly inherited Alzheimer's network trials: An opportunity to prevent Alzheimer's disease Alzheimer's & Dementia. 8: P426-P426. DOI: 10.1016/J.Jalz.2012.05.1135  0.453
2012 Kinnunen K, Cash D, Liang Y, Leung K, Cardoso M, Modat M, Malone I, Yeatman T, Nicholas J, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, ... ... Bateman R, et al. Cross-sectional cerebral volumetric differences and associations with estimated time to age-at-onset in familial Alzheimer's disease: Findings from the DIAN study Alzheimers & Dementia. 8: 23. DOI: 10.1016/J.Jalz.2012.05.064  0.423
2012 Cash D, Ridgway G, Ryan N, Kinnunen K, Yeatman T, Malone I, Benzinger T, Koeppe R, Jack C, Raichle M, Marcus D, Ringman J, Thompson P, Saykin A, Salloway S, ... ... Bateman R, et al. A voxel-based morphometry study of volumetric MRI in familial Alzheimer’s disease Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.052  0.367
2012 Bateman R, Benzinger T, Cairns N, Fagan A, Goate A, Marcus D, Storandt M, Xiong C, Buckles V, Holtzman D, Moulder K, Oliver A, Santacruz A, Fox N, Ghetti B, et al. Presymptomatic Alzheimer's disease in the Dominantly Inherited Alzheimer's Network (DIAN) Alzheimers & Dementia. 8: 4. DOI: 10.1016/J.Jalz.2012.05.015  0.605
2011 Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Science Translational Medicine. 3: 89ra57. PMID 21715678 DOI: 10.1126/Scitranslmed.3002156  0.793
2011 Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, ... ... Bateman R, et al. Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction. Annals of Neurology. 69: 1026-31. PMID 21681798 DOI: 10.1002/Ana.22343  0.581
2011 Bateman RJ, Aisen PS, De Strooper B, Fox NC, Lemere CA, Ringman JM, Salloway S, Sperling RA, Windisch M, Xiong C. Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimer's Research & Therapy. 3: 1. PMID 21211070 DOI: 10.1186/Alzrt59  0.433
2011 Elbert DL, Patterson BW, Ercole L, Ovod V, Kasten T, Mawuenyega K, Yarasheski K, Morris JC, Benzinger T, Holtzman DM, Bateman RJ. Reply to: Fractional synthesis and clearance rates for amyloid β Nature Medicine. 17: 1179-1180. DOI: 10.1038/Nm.2496  0.403
2011 Fagan A, Xiong C, Bateman R, Goate A, Holtzman D, Ghetti B, Martins R, Masters C, Mayeux R, Ringman J, Rossor M, Salloway S, Schofield P, Sperling R, Morris J. O2-01-01: Plasma and Cerebrospinal Fluid Markers in the DIAN Study of Autosomal-Dominant Alzheimer's Disease Alzheimer's & Dementia. 7: S287-S287. DOI: 10.1016/j.jalz.2011.05.833  0.304
2011 Waring J, Slats D, Gonzales C, Dean R, Lee D, Siemers E, Claassen J, Li J, LeBlond D, Slemmon R, Bateman R, Tong G, Fox G. An assessment of variability in CSF biomarkers in clinical experimental models: a meta-analysis Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.249  0.359
2011 Fagan A, Xiong C, Bateman R, Goate A, Holtzman D, Ghetti B, Martins R, Masters C, Mayeux R, Ringman J, Rossor M, Salloway S, Schofield P, Sperling R, Morris J. Plasma and Cerebrospinal Fluid Markers in the DIAN Study of Autosomal-Dominant Alzheimer’s Disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1960  0.489
2010 Mawuenyega KG, Sigurdson W, Ovod V, Munsell L, Kasten T, Morris JC, Yarasheski KE, Bateman RJ. Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science (New York, N.Y.). 330: 1774. PMID 21148344 DOI: 10.1126/Science.1197623  0.493
2010 Bateman RJ. O2-03-05: Amyloid-beta production and clearance rates in Alzheimer's disease Alzheimer's & Dementia. 6: S101-S101. DOI: 10.1016/j.jalz.2010.05.318  0.33
2010 Hata S, Urakami K, Fagan A, Peskind E, Akatsu H, Maeda M, Levey A, Chung KA, Montine T, Leverenz J, Goate A, Bateman R, Holtzman DM, Gandy S, Suzuki T. P3-171: Gamma-secretase dysfunction in sporadic Alzhemer's disease suggested by p3-Alc peptide, metabolic product of Alcadein Alzheimer's & Dementia. 6: S499-S500. DOI: 10.1016/J.Jalz.2010.05.1669  0.483
2009 Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM. Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle. Science (New York, N.Y.). 326: 1005-7. PMID 19779148 DOI: 10.1126/Science.1180962  0.765
2009 Bateman RJ, Siemers ER, Mawuenyega KG, Wen G, Browning KR, Sigurdson WC, Yarasheski KE, Friedrich SW, Demattos RB, May PC, Paul SM, Holtzman DM. A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system. Annals of Neurology. 66: 48-54. PMID 19360898 DOI: 10.1002/Ana.21623  0.501
2009 Hata S, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Fagan A, Goate A, Bateman R, Holtzman DM, Nakaya T, Gandy S, Suzuki T. P2-190: p3-Alc peptides produced by covariant processing of Alcadein and APP implicate γ-secretase dysfunction in sporadic Alzheimer's disease Alzheimer's & Dementia. 5: P316-P317. DOI: 10.1016/J.Jalz.2009.04.502  0.551
2008 Bateman RJ, Klunk WE. Measuring Target Effect of Proposed Disease-Modifying Therapies in Alzheimer's Disease Neurotherapeutics. 5: 381-390. PMID 18625449 DOI: 10.1016/j.nurt.2008.05.009  0.415
2007 Bateman RJ, Munsell LY, Chen X, Holtzman DM, Yarasheski KE. Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates. Journal of the American Society For Mass Spectrometry. 18: 997-1006. PMID 17383190 DOI: 10.1016/J.Jasms.2007.02.009  0.438
2007 Bateman RJ, Wen G, Morris JC, Holtzman DM. Fluctuations of CSF amyloid-beta levels: implications for a diagnostic and therapeutic biomarker. Neurology. 68: 666-9. PMID 17325273 DOI: 10.1212/01.Wnl.0000256043.50901.E3  0.455
2006 Yin KJ, Cirrito JR, Yan P, Hu X, Xiao Q, Pan X, Bateman R, Song H, Hsu FF, Turk J, Xu J, Hsu CY, Mills JC, Holtzman DM, Lee JM. Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 10939-48. PMID 17065436 DOI: 10.1523/Jneurosci.2085-06.2006  0.712
2006 Bateman RJ, Munsell LY, Morris JC, Swarm R, Yarasheski KE, Holtzman DM. Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo. Nature Medicine. 12: 856-61. PMID 16799555 DOI: 10.1038/Nm1438  0.547
2006 Yan P, Hu X, Song H, Yin K, Bateman RJ, Cirrito JR, Xiao Q, Hsu FF, Turk JW, Xu J, Hsu CY, Holtzman DM, Lee JM. Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ. The Journal of Biological Chemistry. 281: 24566-74. PMID 16787929 DOI: 10.1074/Jbc.M602440200  0.654
2006 Li Y, Wang G, Xiong C, McDade E, Fagan AM, Gordon BA, Benzinger TL, Aschenbrenner AJ, Hassenstab J, Bateman RJ. P2-072: A STATISTICAL METHOD FOR DETERMINING BIOMARKER THRESHOLD FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P694-P695. DOI: 10.1016/J.Jalz.2018.06.757  0.575
2006 Sato C, Barthélemy NR, Mawuenyega KG, Patterson BW, Gordon BA, Kanaan NM, Benzinger TL, Miller TM, Karch C, Bateman RJ. O3-01-03: TAU KINETICS IN NEURONS AND IN THE HUMAN CNS Alzheimer's & Dementia. 14: P1008-P1009. DOI: 10.1016/J.Jalz.2018.06.2772  0.613
2006 Joe EB, Joseph-Mathurin N, Benzinger TL, Bateman RJ, McDade E, Ghetti BF, Levin J, Vöglein J, Fox NC, Sperling RA, Chhatwal JP, Noble J, Salloway S, Chui HC, Ringman JM. P4-094: OCCIPITAL TO GLOBAL PIB UPTAKE IS ASSOCIATED WITH THE PRESENCE OF MICROHEMORRHAGES AND MUTATIONS ASSOCIATED WITH CEREBRAL AMYLOID ANGIOPATHY IN THE DOMINANTLY INHERITED ALZHEIMER'S NETWORK Alzheimer's & Dementia. 14: P1472-P1473. DOI: 10.1016/J.Jalz.2018.06.2497  0.305
2006 Wildburger NC, Day GS, Sigurdson W, Sullivan M, Peters A, Schmidt RE, Bateman RJ. P3-071: IN VIVO STABLE ISOTOPE LABELING AND QUANTITATIVE MASS SPECTROMETRY IMAGING OF Aβ PLAQUE DEPOSITION AND TAUOPATHY IN HUMAN AD BRAIN Alzheimer's & Dementia. 14: P1091-P1092. DOI: 10.1016/J.Jalz.2018.06.1427  0.776
2006 Wang G, Xiong C, McDade E, Li Y, Aschenbrenner AJ, Hassenstab J, Fagan AM, Gordon BA, Benzinger TL, Morris JC, Bateman RJ. P1-119: CROSS-SECTIONAL AND LONGITUDINAL RELATIONSHIPS AMONG BIOMARKERS FOR DOMINANTLY INHERITED ALZHEIMER'S DISEASE AND ITS COMPARISON WITH SPORADIC AD Alzheimer's & Dementia. 14: P316-P316. DOI: 10.1016/J.Jalz.2018.06.122  0.606
2006 Dobrowolska Zakaria JA, Bateman RJ, Patterson BW, Vassar RJ. P1-027: KINETIC BEHAVIOR OF NEWLY GENERATED BACE1-CLEAVED APP IN THE HUMAN CENTRAL NERVOUS SYSTEM IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P276-P276. DOI: 10.1016/j.jalz.2018.06.028  0.35
2006 Bateman RJ, Munsell L, Morris JC, Yarasheski K, Holtzman DM. P2-143: Quantitation of in vivo amyloid-beta synthesis and clearance rates in humans using stable isotope labeling and mass spectrometry Alzheimer's & Dementia. 2: S275-S275. DOI: 10.1016/J.Jalz.2006.05.981  0.397
Show low-probability matches.