Javier Cuevas, PhD - Publications

Affiliations: 
Molecular Pharmacology & Physiology University of South Florida, Tampa, FL, United States 
Area:
Ion channels

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Katnik C, Cuevas J. Loop Diuretics Inhibit Ischemia-Induced Intracellular Ca Overload in Neurons the Inhibition of Voltage-Gated Ca and Na Channels. Frontiers in Pharmacology. 12: 732922. PMID 34603048 DOI: 10.3389/fphar.2021.732922  0.777
2020 Motawe ZY, Abdelmaboud SS, Cuevas J, Breslin JW. PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activation. The International Journal of Biochemistry & Cell Biology. 126: 105803. PMID 32668330 DOI: 10.1016/J.Biocel.2020.105803  0.383
2019 Behensky AA, Katnik C, Yin H, Cuevas J. Activation of Sigma Receptors With Afobazole Modulates Microglial, but Not Neuronal, Apoptotic Gene Expression in Response to Long-Term Ischemia Exposure. Frontiers in Neuroscience. 13: 414. PMID 31156357 DOI: 10.3389/Fnins.2019.00414  0.775
2017 Takemoto Y, Slough DP, Meinke G, Katnik C, Graziano ZA, Chidipi B, Reiser M, Alhadidy MM, Ramirez R, Salvador-Montañés O, Ennis S, Guerrero-Serna G, Haburcak M, Diehl C, Cuevas J, et al. Structural basis for the antiarrhythmic blockade of a potassium channel with a small molecule. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29162702 DOI: 10.1096/Fj.201700349R  0.738
2017 Trujillo AN, Katnik C, Cuevas J, Cha B, Taylor-Clark TE, Breslin JW. Modulation of Mesenteric Collecting Lymphatic Contractions by Sigma-1 Receptor Activation and Nitric Oxide Production. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00702.2016. PMID 28778917 DOI: 10.1152/Ajpheart.00702.2016  0.76
2017 Emmons MF, Anreddy N, Cuevas J, Steinberger K, Yang S, McLaughlin M, Silva A, Hazlehurst LA. MTI-101 treatment inducing activation of Stim1 and TRPC1 expression is a determinant of response in multiple myeloma. Scientific Reports. 7: 2685. PMID 28578393 DOI: 10.1038/S41598-017-02713-0  0.352
2016 Tur J, Chapalamadugu KC, Katnik C, Cuevas J, Bhatnagar A, Tipparaju SM. Kvβ1.1 senses pyridine nucleotide changes in the mouse heart and modulates cardiac electrical activity. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00281.2016. PMID 27986658 DOI: 10.1152/Ajpheart.00281.2016  0.728
2016 Katnik C, Garcia A, Behensky AA, Yasny IE, Shuster AM, Seredenin SB, Petrov AV, Cuevas J. Activation of σ1 and σ2 receptors by afobazole increases glial cell survival and prevents glial cell activation and nitrosative stress after ischemic stroke. Journal of Neurochemistry. PMID 27488244 DOI: 10.1111/Jnc.13756  0.754
2015 Aaltonen T, Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Agnew JP, Alexeev GD, Alkhazov G, Alton A, Amerio S, Amidei D, Anastassov A, Annovi A, Antos J, ... ... Cuevas J, et al. Tevatron Combination of Single-Top-Quark Cross Sections and Determination of the Magnitude of the Cabibbo-Kobayashi-Maskawa Matrix Element V_{tb}. Physical Review Letters. 115: 152003. PMID 26550718 DOI: 10.1103/Physrevlett.115.152003  0.439
2015 Aaltonen T, Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Agnew JP, Alexeev GD, Alkhazov G, Alton A, Amerio S, Amidei D, Anastassov A, Annovi A, Antos J, ... ... Cuevas J, et al. Tevatron constraints on models of the Higgs boson with exotic spin and parity using decays to bottom-antibottom quark pairs. Physical Review Letters. 114: 151802. PMID 25933309 DOI: 10.1103/Physrevlett.114.151802  0.409
2014 Aaltonen T, Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Agnew JP, Alexeev GD, Alkhazov G, Alton A, Amerio S, Amidei D, Anastassov A, Annovi A, Antos J, ... ... Cuevas J, et al. Observation of s-channel production of single top quarks at the Tevatron. Physical Review Letters. 112: 231803. PMID 24972197 DOI: 10.1103/Physrevlett.112.231803  0.461
2014 Mari Y, Katnik C, Cuevas J. σ-1 Receptor Inhibition of ASIC1a Channels is Dependent on a Pertussis Toxin-Sensitive G-Protein and an AKAP150/Calcineurin Complex. Neurochemical Research. PMID 24925261 DOI: 10.1007/S11064-014-1324-0  0.795
2014 Katnik C, Cuevas J. Non-specific inhibition of ischemia- and acidosis-induced intracellular calcium elevations and membrane currents by α-phenyl-N-tert-butylnitrone, butylated hydroxytoluene and trolox. International Journal of Molecular Sciences. 15: 3596-611. PMID 24583849 DOI: 10.3390/Ijms15033596  0.776
2014 Katnik C, Garcia A, Behensky AA, Yasny IE, Shuster AM, Seredenin SB, Petrov AV, Seifu S, McAleer J, Willing A, Cuevas J. Treatment with afobazole at delayed time points following ischemic stroke improves long-term functional and histological outcomes. Neurobiology of Disease. 62: 354-64. PMID 24141021 DOI: 10.1016/J.Nbd.2013.10.011  0.731
2013 Behensky AA, Yasny IE, Shuster AM, Seredenin SB, Petrov AV, Cuevas J. Afobazole activation of σ-1 receptors modulates neuronal responses to amyloid-β25-35. The Journal of Pharmacology and Experimental Therapeutics. 347: 468-77. PMID 24006338 DOI: 10.1124/Jpet.113.208330  0.423
2013 Behensky AA, Yasny IE, Shuster AM, Seredenin SB, Petrov AV, Cuevas J. Stimulation of sigma receptors with afobazole blocks activation of microglia and reduces toxicity caused by amyloid-β25-35. The Journal of Pharmacology and Experimental Therapeutics. 347: 458-67. PMID 24006337 DOI: 10.1124/Jpet.113.208348  0.328
2013 Achyuta AK, Conway AJ, Crouse RB, Bannister EC, Lee RN, Katnik CP, Behensky AA, Cuevas J, Sundaram SS. A modular approach to create a neurovascular unit-on-a-chip. Lab On a Chip. 13: 542-53. PMID 23108480 DOI: 10.1039/C2Lc41033H  0.741
2013 Behensky AA, Cortes-Salva M, Seminerio MJ, Matsumoto RR, Antilla JC, Cuevas J. In vitro evaluation of guanidine analogs as sigma receptor ligands for potential anti-stroke therapeutics. The Journal of Pharmacology and Experimental Therapeutics. 344: 155-66. PMID 23065135 DOI: 10.1124/Jpet.112.199513  0.397
2011 Cuevas J, Behensky A, Deng W, Katnik C. Afobazole modulates neuronal response to ischemia and acidosis via activation of σ-1 receptors Journal of Pharmacology and Experimental Therapeutics. 339: 152-160. PMID 21715562 DOI: 10.1124/Jpet.111.182774  0.786
2011 Cuevas J, Rodriguez A, Behensky A, Katnik C. Afobazole modulates microglial function via activation of both σ-1 and σ-2 receptors Journal of Pharmacology and Experimental Therapeutics. 339: 161-172. PMID 21715561 DOI: 10.1124/Jpet.111.182816  0.442
2011 Yanamandra N, Buzzeo RW, Gabriel M, Hazlehurst LA, Mari Y, Beaupre DM, Cuevas J. Tipifarnib-induced apoptosis in acute myeloid leukemia and multiple myeloma cells depends on Ca2+ influx through plasma membrane Ca2+ channels. The Journal of Pharmacology and Experimental Therapeutics. 337: 636-43. PMID 21378206 DOI: 10.1124/Jpet.110.172809  0.387
2010 Mari Y, Katnik C, Cuevas J. ASIC1a channels are activated by endogenous protons during ischemia and contribute to synergistic potentiation of intracellular Ca2+ overload during ischemia and acidosis Cell Calcium. 48: 70-82. PMID 20678793 DOI: 10.1016/J.Ceca.2010.07.002  0.783
2009 Zhang H, Katnik C, Cuevas J. Sigma receptor activation inhibits voltage-gated sodium channels in rat intracardiac ganglion neurons. International Journal of Physiology, Pathophysiology and Pharmacology. 2: 1-11. PMID 21383893  0.81
2009 Ajmo CT, Collier LA, Leonardo CC, Hall AA, Green SM, Womble TA, Cuevas J, Willing AE, Pennypacker KR. Blockade of adrenoreceptors inhibits the splenic response to stroke. Experimental Neurology. 218: 47-55. PMID 19371742 DOI: 10.1016/J.Expneurol.2009.03.044  0.359
2009 Pollock VV, Pastoor T, Katnik C, Cuevas J, Wecker L. Cyclic AMP-dependent protein kinase A and protein kinase C phosphorylate alpha4beta2 nicotinic receptor subunits at distinct stages of receptor formation and maturation. Neuroscience. 158: 1311-25. PMID 19101612 DOI: 10.1016/J.Neuroscience.2008.11.032  0.361
2009 Hall AA, Herrera Y, Ajmo CT, Cuevas J, Pennypacker KR. Sigma receptors suppress multiple aspects of microglial activation. Glia. 57: 744-54. PMID 19031439 DOI: 10.1002/Glia.20802  0.721
2008 Herrera Y, Katnik C, Rodriguez JD, Hall AA, Willing A, Pennypacker KR, Cuevas J. sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons. The Journal of Pharmacology and Experimental Therapeutics. 327: 491-502. PMID 18723775 DOI: 10.1124/Jpet.108.143974  0.809
2007 Song S, Song S, Zhang H, Cuevas J, Sanchez-Ramos J. Comparison of neuron-like cells derived from bone marrow stem cells to those differentiated from adult brain neural stem cells. Stem Cells and Development. 16: 747-56. PMID 17999596 DOI: 10.1089/Scd.2007.0027  0.535
2007 McCord AM, Cuevas J, Anderson BE. Bartonella-induced endothelial cell proliferation is mediated by release of calcium from intracellular stores Dna and Cell Biology. 26: 657-663. PMID 17678436 DOI: 10.1089/Dna.2007.0592  0.349
2006 Katnik C, Guerrero WR, Pennypacker KR, Herrera Y, Cuevas J. Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia. The Journal of Pharmacology and Experimental Therapeutics. 319: 1355-65. PMID 16988055 DOI: 10.1124/Jpet.106.107557  0.801
2006 Ajmo CT, Vernon DO, Collier L, Pennypacker KR, Cuevas J. Sigma receptor activation reduces infarct size at 24 hours after permanent middle cerebral artery occlusion in rats. Current Neurovascular Research. 3: 89-98. PMID 16719792 DOI: 10.2174/156720206776875849  0.422
2006 Hall A, Cruz Y, Katnik C, Cuevas J, Pennypacker K. Sigma receptor agonists suppress the activation of microglia and the subsequent release of cytotoxins Experimental Neurology. 198: 570-571. DOI: 10.1016/J.Expneurol.2006.02.047  0.355
2005 Zhang H, Cuevas J. sigma Receptor activation blocks potassium channels and depresses neuroexcitability in rat intracardiac neurons. The Journal of Pharmacology and Experimental Therapeutics. 313: 1387-96. PMID 15764734 DOI: 10.1124/Jpet.105.084152  0.672
2004 Severance EG, Cuevas J. Distribution and synaptic localization of nicotinic acetylcholine receptors containing a novel α7 subunit isoform in embryonic rat cortical neurons Neuroscience Letters. 372: 104-109. PMID 15531097 DOI: 10.1016/J.Neulet.2004.09.020  0.343
2004 Severance EG, Zhang H, Cruz Y, Pakhlevaniants S, Hadley SH, Amin J, Wecker L, Reed C, Cuevas J. The alpha7 nicotinic acetylcholine receptor subunit exists in two isoforms that contribute to functional ligand-gated ion channels. Molecular Pharmacology. 66: 420-9. PMID 15322233 DOI: 10.1124/Mol.104.000059  0.575
2004 DeHaven WI, Cuevas J. VPAC receptor modulation of neuroexcitability in intracardiac neurons: Dependence on intracellular calcium mobilization and synergistic enhancement by PAC1 receptor activation Journal of Biological Chemistry. 279: 40609-40621. PMID 15280371 DOI: 10.1074/Jbc.M404743200  0.5
2002 DeHaven WI, Cuevas J. Heterogeneity of pituitary adenylate cyclase-activating polypeptide and vasoactive intestinal polypeptide receptors in rat intrinsic cardiac neurons Neuroscience Letters. 328: 45-49. PMID 12123856 DOI: 10.1016/S0304-3940(02)00445-7  0.44
2002 Zhang H, Cuevas J. Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons. Journal of Neurophysiology. 87: 2867-79. PMID 12037190 DOI: 10.1152/Jn.2002.87.6.2867  0.683
2000 Cuevas J, Adams DJ. Substance P preferentially inhibits large conductance nicotinic ACh receptor channels in rat intracardiac ganglion neurons. Journal of Neurophysiology. 84: 1961-70. PMID 11024089 DOI: 10.1152/Jn.2000.84.4.1961  0.617
2000 Liu DM, Cuevas J, Adams DJ. VIP and PACAP potentiation of nicotinic ACh-evoked currents in rat parasympathetic neurons is mediated by G-protein activation. The European Journal of Neuroscience. 12: 2243-51. PMID 10947803 DOI: 10.1046/J.1460-9568.2000.00116.X  0.69
2000 Cuevas J, Roth AL, Berg DK. Two distinct classes of functional 7-containing nicotinic receptor on rat superior cervical ganglion neurons. The Journal of Physiology. 525: 735-46. PMID 10856125 DOI: 10.1111/J.1469-7793.2000.T01-1-00735.X  0.381
1998 Loughnan M, Bond T, Atkins A, Cuevas J, Adams DJ, Broxton NM, Livett BG, Down JG, Jones A, Alewood PF, Lewis RJ. alpha-conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 273: 15667-74. PMID 9624161 DOI: 10.1074/Jbc.273.25.15667  0.563
1998 Cuevas J, Berg DK. Mammalian Nicotinic Receptors with α7 Subunits That Slowly Desensitize and Rapidly Recover from α-Bungarotoxin Blockade The Journal of Neuroscience. 18: 10335-10344. DOI: 10.1523/Jneurosci.18-24-10335.1998  0.37
1997 Cuevas J, Adams DJ. M4 muscarinic receptor activation modulates calcium channel currents in rat intracardiac neurons. Journal of Neurophysiology. 78: 1903-12. PMID 9325359 DOI: 10.1152/Jn.1997.78.4.1903  0.676
1997 Cuevas J, Harper AA, Trequattrini C, Adams DJ. Passive and active membrane properties of isolated rat intracardiac neurons: regulation by H- and M-currents. Journal of Neurophysiology. 78: 1890-902. PMID 9325358 DOI: 10.1152/Jn.1997.78.4.1890  0.595
1997 Poth K, Nutter TJ, Cuevas J, Parker MJ, Adams DJ, Luetje CW. Heterogeneity of nicotinic receptor class and subunit mRNA expression among individual parasympathetic neurons from rat intracardiac ganglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 586-96. PMID 8987781 DOI: 10.1523/Jneurosci.17-02-00586.1997  0.75
1996 Cuevas J, Adams DJ. Vasoactive intestinal polypeptide modulation of nicotinic ACh receptor channels in rat intracardiac neurones. The Journal of Physiology. 493: 503-15. PMID 8782112 DOI: 10.1113/Jphysiol.1996.Sp021399  0.639
1994 Cuevas J, Adams DJ. Local anaesthetic blockade of neuronal nicotinic ACh receptor-channels in rat parasympathetic ganglion cells. British Journal of Pharmacology. 111: 663-72. PMID 7517326 DOI: 10.1111/J.1476-5381.1994.Tb14789.X  0.635
1993 Cuevas J, Harper AA, Adams DJ. Membrane properties and discharge characteristics of rat intracardiac neurones in vitro: the effect of temperature The Journal of Physiology. 356. DOI: 10.1113/Jphysiol.1993.Sp019755  0.541
1991 Cuevas J, Bassett AL, Cameron JS, Furukawa T, Myerburg RJ, Kimura S. Effect of H+ on ATP-regulated K+ channels in feline ventricular myocytes American Journal of Physiology - Heart and Circulatory Physiology. 261: H755-H761. PMID 1887923 DOI: 10.1152/Ajpheart.1991.261.3.H755  0.335
1990 Kimura S, Bassett AL, Furukawa T, Cuevas J, Myerburg RJ. Electrophysiological properties and responses to simulated ischemia in cat ventricular myocytes of endocardial and epicardial origin Circulation Research. 66: 469-477. PMID 2297813 DOI: 10.1161/01.Res.66.2.469  0.331
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