Tian Xia, M.D./Ph.D. - Publications

Affiliations: 
2001- University of California, Los Angeles, Los Angeles, CA 
Area:
nanomedicine, nanotoxicity, toxicity, public health

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kusumoputro S, Au C, Lam KH, Park N, Hyun A, Kusumoputro E, Wang X, Xia T. Liver-Targeting Nanoplatforms for the Induction of Immune Tolerance. Nanomaterials (Basel, Switzerland). 14. PMID 38202522 DOI: 10.3390/nano14010067  0.385
2023 Li J, Xiao Y, Zhang Y, Li S, Zhao M, Xia T, Meng H. Pulmonary Delivery of Specialized Pro-Resolving Mediators-Based Nanotherapeutics Attenuates Pulmonary Fibrosis in Preclinical Animal Models. Acs Nano. PMID 37535431 DOI: 10.1021/acsnano.2c10388  0.807
2023 Xu X, Xia T. Recent Advances in Site-Specific Lipid Nanoparticles for mRNA Delivery. Acs Nanoscience Au. 3: 192-203. PMID 37360845 DOI: 10.1021/acsnanoscienceau.2c00062  0.317
2023 Chen YH, Nguyen D, Brindley S, Ma T, Xia T, Brune J, Brown JM, Tsai CS. The dependence of particle size on cell toxicity for modern mining dust. Scientific Reports. 13: 5101. PMID 36991007 DOI: 10.1038/s41598-023-31215-5  0.757
2023 Xu X, Wang X, Liao YP, Luo L, Xia T, Nel AE. Use of a Liver-Targeting Immune-Tolerogenic mRNA Lipid Nanoparticle Platform to Treat Peanut-Induced Anaphylaxis by Single- and Multiple-Epitope Nucleotide Sequence Delivery. Acs Nano. PMID 36853930 DOI: 10.1021/acsnano.2c12420  0.804
2022 Su Y, Zhou X, Meng H, Xia T, Liu H, Rolshausen P, Roper C, McLean JE, Zhang Y, Keller AA, Jassby D. Cost-benefit analysis of nanofertilizers and nanopesticides emphasizes the need to improve the efficiency of nanoformulations for widescale adoption. Nature Food. 3: 1020-1030. PMID 37118298 DOI: 10.1038/s43016-022-00647-z  0.468
2022 Li J, Diamante G, Ahn IS, Wijaya D, Wang X, Chang CH, Ha SM, Immadisetty K, Meng H, Nel A, Yang X, Xia T. Determination of the nanoparticle- and cell-specific toxicological mechanisms in 3D liver spheroids using scRNAseq analysis. Nano Today. 47. PMID 36911538 DOI: 10.1016/j.nantod.2022.101652  0.823
2022 Cui L, Wang X, Zhao X, Sun B, Xia T, Hu S. CeO nanoparticles induce pulmonary fibrosis activating S1P pathway as revealed by metabolomics. Nano Today. 45. PMID 36910843 DOI: 10.1016/j.nantod.2022.101559  0.648
2022 Zhang L, Xia T, Liu Q, Gu L, Sun Y, Yang Z. Performance of Daphnia simultaneously exposed to nitrite and predation risk: Reduced nitrite tolerance and aggravated predation-induced miniaturization. The Science of the Total Environment. 859: 160271. PMID 36423840 DOI: 10.1016/j.scitotenv.2022.160271  0.356
2022 Wang W, Zheng H, Jiang J, Li Z, Jiang D, Shi X, Wang H, Jiang J, Xie Q, Gao M, Chu J, Cai X, Xia T, Li R. Engineering micro oxygen factories to slow tumour progression via hyperoxic microenvironments. Nature Communications. 13: 4495. PMID 35918337 DOI: 10.1038/s41467-022-32066-w  0.559
2022 Li J, Chen C, Xia T. Understanding Nanomaterial-Liver Interactions to Facilitate the Development of Safer Nanoapplications. Advanced Materials (Deerfield Beach, Fla.). e2106456. PMID 35029313 DOI: 10.1002/adma.202106456  0.792
2022 Cao W, Wang X, Li J, Yan M, Chang CH, Kim J, Jiang J, Liao YP, Tseng S, Kusumoputro S, Lau C, Huang M, Han P, Lu P, Xia T. NLRP3 inflammasome activation determines the fibrogenic potential of PM air pollution particles in the lung. Journal of Environmental Sciences (China). 111: 429-441. PMID 34949371 DOI: 10.1016/j.jes.2021.04.021  0.803
2021 Liu Q, Wang X, Liao YP, Chang CH, Li J, Xia T, Nel AE. Use of a Liver-targeting Nanoparticle Platform to Intervene in Peanut-induced anaphylaxis through delivery of an Ara h2 T-cell Epitope. Nano Today. 42. PMID 36969911 DOI: 10.1016/j.nantod.2021.101370  0.801
2021 Bondarenko O, Mortimer M, Kahru A, Feliu N, Javed I, Kakinen A, Lin S, Xia T, Song Y, Davis TP, Lynch I, Parak WJ, Leong DT, Ke PC, Chen C, et al. Nanotoxicology and Nanomedicine: The Yin and Yang of Nano-Bio Interactions for the New Decade. Nano Today. 39. PMID 36937379 DOI: 10.1016/j.nantod.2021.101184  0.576
2021 Li J, Wang X, Chang CH, Jiang J, Liu Q, Liu X, Liao YP, Ma T, Meng H, Xia T. Nanocellulose Length Determines the Differential Cytotoxic Effects and Inflammatory Responses in Macrophages and Hepatocytes. Small (Weinheim An Der Bergstrasse, Germany). e2102545. PMID 34363305 DOI: 10.1002/smll.202102545  0.807
2021 Li J, Wang X, Mei KC, Chang CH, Jiang J, Liu X, Liu Q, Guiney LM, Hersam MC, Liao YP, Meng H, Xia T. Lateral size of graphene oxide determines differential cellular uptake and cell death pathways in Kupffer cells, LSECs, and hepatocytes. Nano Today. 37. PMID 34055032 DOI: 10.1016/j.nantod.2020.101061  0.803
2021 Li J, Guiney LM, Downing JR, Wang X, Chang CH, Jiang J, Liu Q, Liu X, Mei KC, Liao YP, Ma T, Meng H, Hersam MC, Nel AE, Xia T. Dissolution of 2D Molybdenum Disulfide Generates Differential Toxicity among Liver Cell Types Compared to Non-Toxic 2D Boron Nitride Effects. Small (Weinheim An Der Bergstrasse, Germany). e2101084. PMID 34032006 DOI: 10.1002/smll.202101084  0.796
2021 Ma T, Xia T. Nanoparticle-Based Activatable Probes for Bioimaging. Advanced Biology. 5: e2000193. PMID 33724732 DOI: 10.1002/adbi.202000193  0.737
2020 Liu Q, Wang X, Liu X, Liao YP, Chang CH, Mei KC, Jiang J, Tseng S, Gochman G, Huang M, Thatcher Z, Li J, Allen SD, Lucido L, Xia T, et al. Antigen- and Epitope-Delivering Nanoparticles Targeting Liver Induce Comparable Immunotolerance in Allergic Airway Disease and Anaphylaxis as Nanoparticle-Delivering Pharmaceuticals. Acs Nano. PMID 33351586 DOI: 10.1021/acsnano.0c09206  0.805
2020 Ma T, Wang X, Li L, Sun B, Zhu Y, Xia T. Electronic cigarette aerosols induce oxidative stress-dependent cell death and NF-κB mediated acute lung inflammation in mice. Archives of Toxicology. PMID 33159582 DOI: 10.1007/s00204-020-02920-1  0.793
2020 Mei KC, Liao YP, Jiang J, Chiang M, Khazaieli M, Liu X, Wang X, Liu Q, Chang CH, Zhang X, Li J, Ji Y, Melano B, Telesca D, Xia T, et al. Liposomal Delivery of Mitoxantrone and a Cholesteryl Indoximod Prodrug Provides Effective Chemo-Immunotherapy in Multiple Solid Tumors. Acs Nano. PMID 32940463 DOI: 10.1021/Acsnano.0C05194  0.789
2020 Wu Q, Shi J, Ji X, Xia T, Zeng L, Li G, Wang Y, Gao J, Yao L, Ma J, Liu X, Liu N, Hu L, He B, Liang Y, et al. Heterogenous Internalization of Nanoparticles at Ultra-Trace Concentration in Environmental Individual Unicellular Organisms Unveiled by Single-Cell Mass Cytometry. Acs Nano. PMID 32931264 DOI: 10.1021/Acsnano.0C03587  0.387
2020 Liu S, Xia T. Continued Efforts on Nanomaterial-Environmental Health and Safety Is Critical to Maintain Sustainable Growth of Nanoindustry. Small (Weinheim An Der Bergstrasse, Germany). e2000603. PMID 32338451 DOI: 10.1002/Smll.202000603  0.333
2020 Wang X, Chang CH, Jiang J, Liu X, Li J, Liu Q, Liao YP, Li L, Nel AE, Xia T. Mechanistic Differences in Cell Death Responses to Metal-Based Engineered Nanomaterials in Kupffer Cells and Hepatocytes. Small (Weinheim An Der Bergstrasse, Germany). e2000528. PMID 32337854 DOI: 10.1002/Smll.202000528  0.812
2020 Qu G, Xia T, Zhou W, Zhang X, Zhang H, Hu L, Shi J, Yu XF, Jiang G. Property-Activity Relationship of Black Phosphorus at the Nano-Bio Interface: From Molecules to Organisms. Chemical Reviews. PMID 31971371 DOI: 10.1021/Acs.Chemrev.9B00445  0.335
2020 Wang Y, Hu L, Xia T, Yao X, Yin Y, Wang F, Song M, Jiang G. High-Throughput Single Cell Analysis Reveals the Heterogeneity of QDots-Induced Response in Macrophages Environmental Science and Technology Letters. 7: 337-342. DOI: 10.1021/Acs.Estlett.0C00278  0.413
2020 Wang X, Chang CH, Jiang J, Liu X, Li J, Liu Q, Liao Y, Li L, Nel AE, Xia T. Metal‐Based Nanoparticles: Mechanistic Differences in Cell Death Responses to Metal‐Based Engineered Nanomaterials in Kupffer Cells and Hepatocytes (Small 21/2020) Small. 16: 2070113. DOI: 10.1002/Smll.202070113  0.804
2019 Zhu J, Li B, Xu M, Liu R, Xia T, Zhang Z, Xu Y, Liu S. Graphene Oxide Promotes Cancer Metastasis through Associating with Plasma Membrane to Promote TGF-β Signaling-Dependent Epithelial-Mesenchymal Transition. Acs Nano. PMID 31877027 DOI: 10.1021/Acsnano.9B07891  0.328
2019 Ji EH, Elzakra N, Chen W, Cui L, Lee ES, Sun B, Messadi D, Xia T, Zhu Y, Hu S. E-cigarette aerosols induce unfolded protein response in normal human oral keratinocytes. Journal of Cancer. 10: 6915-6924. PMID 31839827 DOI: 10.7150/Jca.31319  0.57
2019 Cui L, Wang X, Sun B, Xia T, Hu S. Predictive Metabolomic Signatures for Safety Assessment of Metal Oxide Nanoparticles. Acs Nano. PMID 31682760 DOI: 10.1021/Acsnano.9B05793  0.659
2019 Zheng H, Ji Z, Roy KR, Gao M, Pan Y, Cai X, Wang L, Li W, Chang CH, Kaweeteerawat C, Chen C, Xia T, Zhao Y, Li R. Engineered Graphene Oxide Nanocomposite Capable of Preventing the Evolution of Antimicrobial Resistance. Acs Nano. PMID 31566947 DOI: 10.1021/Acsnano.9B04970  0.601
2019 Wang X, Chang CH, Jiang J, Liu Q, Liao YP, Lu J, Li L, Liu X, Kim J, Ahmed A, Nel AE, Xia T. The Crystallinity and Aspect Ratio of Cellulose Nanomaterials Determine Their Pro-Inflammatory and Immune Adjuvant Effects In Vitro and In Vivo. Small (Weinheim An Der Bergstrasse, Germany). e1901642. PMID 31461215 DOI: 10.1002/Smll.201901642  0.791
2019 Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, ... ... Xia T, et al. Publisher Correction: On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology. PMID 31358944 DOI: 10.1038/S41565-019-0538-3  0.556
2019 Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufès C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, ... ... Xia T, et al. Publisher Correction: On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology. PMID 31289407 DOI: 10.1038/S41565-019-0523-X  0.556
2019 Leong HS, Butler KS, Brinker CJ, Azzawi M, Conlan S, Dufés C, Owen A, Rannard S, Scott C, Chen C, Dobrovolskaia MA, Kozlov SV, Prina-Mello A, Schmid R, Wick P, ... ... Xia T, et al. On the issue of transparency and reproducibility in nanomedicine. Nature Nanotechnology. 14: 629-635. PMID 31270452 DOI: 10.1038/S41565-019-0496-9  0.561
2019 Khademhosseini A, Nel AE, Bunje H, DeSantis CJ, Andrews AM, Blaik RA, Gu Z, Meng H, Ozcan A, Tolbert SH, Xia T, Zink JI, Weiss PS. Nanoscience and Nanotechnology at UCLA. Acs Nano. 13: 6127-6129. PMID 31247733 DOI: 10.1021/Acsnano.9B04680  0.703
2019 Liu Q, Wang X, Liu X, Kumar S, Gochman G, Ji Y, Liao YP, Chang CH, Situ W, Lu J, Jiang J, Mei KC, Meng H, Xia T, Nel AE. Use of Polymeric Nanoparticle Platform Targeting the Liver to Induce Treg-Mediated Antigen-Specific Immune Tolerance in a Pulmonary Allergen Sensitization Model. Acs Nano. PMID 30964276 DOI: 10.1021/Acsnano.9B01444  0.817
2019 Zhang J, Chen Y, Gao M, Wang Z, Liu R, Xia T, Liu S. Silver Nanoparticles Compromise Female Embryonic Stem Cell Differentiation through Disturbing X Chromosome Inactivation. Acs Nano. PMID 30650303 DOI: 10.1021/Acsnano.8B08604  0.317
2018 Chen X, Jiang W, Ahmed A, Mahon CS, Müllner M, Cao B, Xia T. Engineering Protective Polymer Coatings for Liver Microtissues. Chemical Research in Toxicology. PMID 30499291 DOI: 10.1021/Acs.Chemrestox.8B00120  0.369
2018 Hwang R, Mirshafiee V, Zhu Y, Xia T. Current approaches for safer design of engineered nanomaterials. Ecotoxicology and Environmental Safety. 166: 294-300. PMID 30273853 DOI: 10.1016/J.Ecoenv.2018.09.077  0.82
2018 Liu Q, Wang X, Xia T. Creative use of analytical techniques and high-throughput technology to facilitate safety assessment of engineered nanomaterials. Analytical and Bioanalytical Chemistry. PMID 30066194 DOI: 10.1007/S00216-018-1289-Y  0.509
2018 Huang C, Xia T, Niu J, Yang Y, Lin S, Wang X, Yang G, Mao L, Xing B. Transformation of 14C-labeled Graphene to 14CO2 in the Shoots of Rice Plant. Angewandte Chemie (International Ed. in English). PMID 29928789 DOI: 10.1002/Anie.201805099  0.596
2018 Guiney LM, Wang X, Xia T, Nel AE, Hersam MC. Assessing and Mitigating the Hazard Potential of Two-Dimensional Materials. Acs Nano. PMID 29889491 DOI: 10.1021/Acsnano.8B02491  0.649
2018 Wang X, Lee JH, Li R, Liao YP, Kang J, Chang CH, Guiney LM, Mirshafiee V, Li L, Lu J, Xia T, Hersam MC, Nel AE. Toxicological Profiling of Highly Purified Single-Walled Carbon Nanotubes with Different Lengths in the Rodent Lung and Escherichia Coli. Small (Weinheim An Der Bergstrasse, Germany). e1703915. PMID 29733549 DOI: 10.1002/Smll.201703915  0.8
2018 Mirshafiee V, Sun B, Chang CH, Liao YP, Jiang W, Jiang J, Liu X, Wang X, Xia T, Nel AE. Toxicological Profiling of Metal Oxide Nanoparticles in Liver Context Reveals Pyroptosis in Kupffer Cells and Macrophages Versus Apoptosis in Hepatocytes. Acs Nano. PMID 29543433 DOI: 10.1021/Acsnano.8B01086  0.825
2018 Amorim MJB, Lin S, Schlich K, Navas JM, Brunelli A, Neubauer N, Vilsmeier K, Costa AL, Gondikas A, Xia T, Galbis L, Badetti E, Marcomini A, Hristozov D, Kammer FV, et al. Environmental Impacts by Fragments Released from Nanoenabled Products: A Multiassay, Multimaterial Exploration by the SUN Approach. Environmental Science & Technology. PMID 29376638 DOI: 10.1021/Acs.Est.7B04122  0.75
2018 Li R, Guiney LM, Chang CH, Mansukhani ND, Ji Z, Wang X, Liao YP, Jiang W, Sun B, Hersam MC, Nel AE, Xia T. The Surface Oxidation of Graphene Oxide Determines Membrane Damage, Lipid Peroxidation, and Cytotoxicity in Macrophages in a Pulmonary Toxicity Model. Acs Nano. PMID 29328670 DOI: 10.1021/Acsnano.7B07737  0.816
2018 Qi Y, Liu Y, Xia T, Xu A, Liu S, Chen W. The biotransformation of graphene oxide in lung fluids significantly alters its inherent properties and bioactivities toward immune cells Npg Asia Materials. 10: 385-396. DOI: 10.1038/S41427-018-0039-0  0.396
2018 Liu Y, Peng J, Wang S, Xu M, Gao M, Xia T, Weng J, Xu A, Liu S. Molybdenum disulfide/graphene oxide nanocomposites show favorable lung targeting and enhanced drug loading/tumor-killing efficacy with improved biocompatibility Npg Asia Materials. 10: e458-e458. DOI: 10.1038/Am.2017.225  0.358
2018 Xia T. Upconversion nanoparticle mediated optogenetics for targeted deep brain stimulation Chinese Science Bulletin. 63: 405-407. DOI: 10.1016/J.Scib.2018.03.004  0.301
2017 Dong S, Xia T, Yang Y, Lin S, Mao L. Bioaccumulation of 14C-labled Graphene in an Aquatic Food Chain through Direct Uptake or Trophic Transfer. Environmental Science & Technology. PMID 29265813 DOI: 10.1021/Acs.Est.7B04339  0.587
2017 Qu G, Liu W, Zhao Y, Gao J, Xia T, Shi J, Hu L, Zhou W, Gao J, Wang H, Luo Q, Zhou Q, Liu S, Yu X, Jiang G. Chemical modification improves biocompatibility of black phosphorus nanosheets. Angewandte Chemie (International Ed. in English). PMID 28892587 DOI: 10.1002/Anie.201706228  0.311
2017 Cai X, Lee A, Ji Z, Huang C, Chang CH, Wang X, Liao YP, Xia T, Li R. Erratum to: Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation. Particle and Fibre Toxicology. 14: 33. PMID 28851387 DOI: 10.1186/s12989-017-0216-2  0.642
2017 Wang X, Liao YP, Telesca D, Chang CH, Xia T, Nel AE. The Genetic Heterogeneity among Different Mouse Strains Impacts the Lung Injury Potential of Multiwalled Carbon Nanotubes. Small (Weinheim An Der Bergstrasse, Germany). PMID 28677920 DOI: 10.1002/Smll.201700776  0.658
2017 Sun B, Ji Z, Liao YP, Chang CH, Wang X, Ku J, Xue C, Mirshafiee V, Xia T. Enhanced Immune Adjuvant Activity of Aluminum Oxyhydroxide Nanorods through Cationic Surface Functionalization. Acs Applied Materials & Interfaces. PMID 28590715 DOI: 10.1021/Acsami.7B05817  0.791
2017 Wang X, Sun B, Liu S, Xia T. Structure Activity Relationships of Engineered Nanomaterials in inducing NLRP3 Inflammasome Activation and Chronic Lung Fibrosis. Nanoimpact. 6: 99-108. PMID 28480337 DOI: 10.1016/J.Impact.2016.08.002  0.679
2017 Cai X, Lee A, Ji Z, Huang C, Chang CH, Wang X, Liao YP, Xia T, Li R. Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation. Particle and Fibre Toxicology. 14: 13. PMID 28431555 DOI: 10.1186/S12989-017-0193-5  0.7
2017 Mirshafiee V, Jiang W, Sun B, Wang X, Xia T. Facilitating Translational Nanomedicine via Predictive Safety Assessment. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28412168 DOI: 10.1016/J.Ymthe.2017.03.011  0.784
2017 Zhu J, Xu M, Gao M, Zhang Z, Xu Y, Xia T, Liu S. Graphene Oxide-Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents. Acs Nano. PMID 28208020 DOI: 10.1021/Acsnano.6B07311  0.325
2017 Ma J, Li R, Liu Y, Qu G, Liu J, Guo W, Song H, Li X, Liu Y, Xia T, Yan B, Liu S. Carbon Nanotubes Disrupt Iron Homeostasis and Induce Anemia of Inflammation through Inflammatory Pathway as a Secondary Effect Distant to Their Portal-of-Entry. Small (Weinheim An Der Bergstrasse, Germany). PMID 28195425 DOI: 10.1002/Smll.201603830  0.624
2017 Jiang W, Wang X, Osborne OJ, Du Y, Chang CH, Liao YP, Sun B, Jiang J, Ji Z, Li R, Liu X, Lu J, Lin S, Meng H, Xia T, et al. Pro-Inflammatory and Pro-Fibrogenic Effects of Ionic and Particulate Arsenide and Indium-Containing Semiconductor Materials in the Murine Lung. Acs Nano. PMID 28177603 DOI: 10.1021/Acsnano.6B07895  0.798
2017 Osborne OJ, Lin S, Jiang W, Chow J, Chang CH, Ji Z, Yu X, Lin S, Xia T, Nel AE. Differential effect of micron- versus nanoscale III–V particulates and ionic species on the zebrafish gut Environmental Science: Nano. 4: 1350-1364. DOI: 10.1039/C6En00675B  0.59
2017 Ma J, Li R, Liu Y, Qu G, Liu J, Guo W, Song H, Li X, Liu Y, Xia T, Yan B, Liu S. Carbon Nanotubes: Carbon Nanotubes Disrupt Iron Homeostasis and Induce Anemia of Inflammation through Inflammatory Pathway as a Secondary Effect Distant to Their Portal-of-Entry (Small 15/2017) Small. 13. DOI: 10.1002/Smll.201770084  0.581
2016 Sun B, Xia T. Nanomaterial-Based Vaccine Adjuvants. Journal of Materials Chemistry. B. 4: 5496-5509. PMID 30774955 DOI: 10.1039/C6Tb01131D  0.572
2016 Xia T, Zhu Y, Mu L, Zhang ZF, Liu S. Pulmonary diseases induced by ambient ultrafine and engineered nanoparticles in twenty-first century. National Science Review. 3: 416-429. PMID 28649460 DOI: 10.1093/Nsr/Nww064  0.359
2016 Ji EH, Sun B, Zhao T, Shu S, Chang CH, Messadi D, Xia T, Zhu Y, Hu S. Correction: Characterization of Electronic Cigarette Aerosol and Its Induction of Oxidative Stress Response in Oral Keratinocytes. Plos One. 11: e0169380. PMID 28033425 DOI: 10.1371/journal.pone.0169380  0.505
2016 Naatz H, Lin S, Li R, Jiang W, Ji Z, Chang CH, Koeser J, Thöming J, Xia T, Nel AE, Mädler L, Pokhrel S. Safe-by-Design of CuO Nanoparticles via Fe-Doping, Cu-O Bond Lengths Variation, and Biological Assessment in Cells and Zebrafish Embryos. Acs Nano. PMID 28026936 DOI: 10.1021/Acsnano.6B06495  0.796
2016 Li R, Mansukhani ND, Guiney LM, Ji Z, Zhao Y, Chang CH, French CT, Miller JF, Hersam MC, Nel AE, Xia T. Identification and Optimization of Carbon Radicals on Hydrated Graphene Oxide for Ubiquitous Antibacterial Coatings. Acs Nano. 10: 10966-10980. PMID 28024366 DOI: 10.1021/acsnano.6b05692  0.712
2016 Ma J, Li R, Qu G, Liu H, Yan B, Xia T, Liu Y, Liu S. Carbon nanotubes stimulate synovial inflammation by inducing systemic pro-inflammatory cytokines. Nanoscale. PMID 27714147 DOI: 10.1039/C6Nr06041B  0.62
2016 Sisler JD, Li R, McKinney W, Mercer RR, Ji Z, Xia T, Wang X, Shaffer J, Orandle M, Mihalchik AL, Battelli L, Chen BT, Wolfarth M, Andrew ME, Schwegler-Berry D, et al. Differential pulmonary effects of CoO and La2O3 metal oxide nanoparticle responses during aerosolized inhalation in mice. Particle and Fibre Toxicology. 13: 42. PMID 27527840 DOI: 10.1186/S12989-016-0155-3  0.772
2016 Sun B, Wang X, Liao YP, Ji Z, Chang CH, Pokhrel S, Ku J, Liu X, Wang M, Dunphy DR, Li R, Meng H, Mädler L, Brinker CJ, Nel AE, ... Xia T, et al. Repetitive Dosing of Fumed Silica Leads to Pro-Fibrogenic Effects Through Unique Structure-Activity Relationships and Biopersistence in the Lung. Acs Nano. PMID 27483033 DOI: 10.1021/Acsnano.6B04143  0.799
2016 Sun B, Taing A, Liu H, Nie G, Wang J, Fang Y, Liu L, Xue Y, Shi J, Liao YP, Ku J, Xia T, Liu Y. Nerve Growth Factor-Conjugated Mesoporous Silica Nanoparticles Promote Neuron-Like PC12 Cell Proliferation and Neurite Growth. Journal of Nanoscience and Nanotechnology. 16: 2390-3. PMID 27455646 DOI: 10.1166/Jnn.2016.10958  0.571
2016 Ji EH, Sun B, Zhao T, Shu S, Chang CH, Messadi D, Xia T, Zhu Y, Hu S. Characterization of Electronic Cigarette Aerosol and Its Induction of Oxidative Stress Response in Oral Keratinocytes. Plos One. 11: e0154447. PMID 27223106 DOI: 10.1371/Journal.Pone.0154447  0.633
2016 Wang X, Mansukhani ND, Guiney LM, Lee JH, Li R, Sun B, Liao YP, Chang CH, Ji Z, Xia T, Hersam MC, Nel AE. Toxicological Profiling of Highly-Purified Metallic and Semiconducting Single-Walled Carbon Nanotubes in the Rodent Lung and E. coli. Acs Nano. PMID 27159184 DOI: 10.1021/Acsnano.6B01560  0.799
2016 Li N, Georas S, Alexis N, Fritz P, Xia T, Williams MA, Horner E, Nel A. A work group report on ultrafine particles (American Academy of Allergy, Asthma & Immunology): Why ambient ultrafine and engineered nanoparticles should receive special attention for possible adverse health outcomes in human subjects. The Journal of Allergy and Clinical Immunology. PMID 27130856 DOI: 10.1016/J.Jaci.2016.02.023  0.643
2015 Jiang W, Lin S, Chang CH, Ji Z, Sun B, Wang X, Li R, Pon N, Xia T, Nel AE. Implications of the Differential Toxicological Effects of III-V Ionic and Particulate Materials for Hazard Assessment of Semiconductor Slurries. Acs Nano. PMID 26549624 DOI: 10.1021/Acsnano.5B04847  0.8
2015 Ma J, Liu R, Wang X, Liu Q, Chen Y, Valle RP, Zuo YY, Xia T, Liu S. A Crucial Role of Lateral Size for Graphene Oxide in Activating Macrophages and Stimulating Pro-inflammatory Responses in Cells and Animals. Acs Nano. PMID 26389709 DOI: 10.1021/Acsnano.5B04751  0.446
2015 Osborne OJ, Lin S, Chang CH, Ji Z, Yu X, Wang X, Lin S, Xia T, Nel AE. Organ-Specific and Size-Dependent Ag Nanoparticle Toxicity in Gills and Intestines of Adult Zebrafish. Acs Nano. PMID 26327297 DOI: 10.1021/Acsnano.5B04583  0.756
2015 Liu R, Liu HH, Ji Z, Chang CH, Xia T, Nel AE, Cohen Y. Evaluation of Toxicity Ranking for Metal Oxide Nanoparticles via an in Vitro Dosimetry Model. Acs Nano. 9: 9303-13. PMID 26284985 DOI: 10.1021/Acsnano.5B04420  0.645
2015 Wang X, Xia T. New insights into disruption of iron homeostasis by environmental pollutants. Journal of Environmental Sciences (China). 34: 256-8. PMID 26257368 DOI: 10.1016/J.Jes.2015.06.001  0.358
2015 Wang X, Mansukhani ND, Guiney LM, Ji Z, Chang CH, Wang M, Liao YP, Song TB, Sun B, Li R, Xia T, Hersam MC, Nel AE. Differences in the Toxicological Potential of 2D versus Aggregated Molybdenum Disulfide in the Lung. Small (Weinheim An Der Bergstrasse, Germany). PMID 26237579 DOI: 10.1002/Smll.201500906  0.808
2015 Sun B, Pokhrel S, Dunphy DR, Zhang H, Ji Z, Wang X, Wang M, Liao YP, Chang CH, Dong J, Li R, Mädler L, Brinker CJ, Nel AE, Xia T. Reduction of Acute Inflammatory Effects of Fumed Silica Nanoparticles in the Lung by Adjusting Silanol Display through Calcination and Metal Doping. Acs Nano. PMID 26200133 DOI: 10.1021/Acsnano.5B03443  0.813
2015 Nel AE, Parak WJ, Chan WC, Xia T, Hersam MC, Brinker CJ, Zink JI, Pinkerton KE, Baer DR, Weiss PS. Where Are We Heading in Nanotechnology Environmental Health and Safety and Materials Characterization? Acs Nano. 9: 5627-30. PMID 26100220 DOI: 10.1021/Acsnano.5B03496  0.647
2015 Zhang H, Wang X, Wang M, Li L, Chang CH, Ji Z, Xia T, Nel AE. Mammalian Cells Exhibit a Range of Sensitivities to Silver Nanoparticles that are Partially Explicable by Variations in Antioxidant Defense and Metallothionein Expression. Small (Weinheim An Der Bergstrasse, Germany). PMID 25930061 DOI: 10.1002/Smll.201500251  0.772
2015 Wang Z, Xia T, Liu S. Mechanisms of nanosilver-induced toxicological effects: more attention should be paid to its sublethal effects. Nanoscale. 7: 7470-81. PMID 25865054 DOI: 10.1039/C5Nr01133G  0.327
2015 Li R, Ji Z, Dong J, Chang CH, Wang X, Sun B, Wang M, Liao YP, Zink JI, Nel AE, Xia T. Enhancing the imaging and biosafety of upconversion nanoparticles through phosphonate coating. Acs Nano. 9: 3293-306. PMID 25727446 DOI: 10.1021/Acsnano.5B00439  0.815
2015 Wang X, Duch MC, Mansukhani N, Ji Z, Liao YP, Wang M, Zhang H, Sun B, Chang CH, Li R, Lin S, Meng H, Xia T, Hersam MC, Nel AE. Use of a pro-fibrogenic mechanism-based predictive toxicological approach for tiered testing and decision analysis of carbonaceous nanomaterials. Acs Nano. 9: 3032-43. PMID 25646681 DOI: 10.1021/Nn507243W  0.793
2015 Sun B, Wang X, Ji Z, Wang M, Liao YP, Chang CH, Li R, Zhang H, Nel AE, Xia T. NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes. Small (Weinheim An Der Bergstrasse, Germany). 11: 2087-97. PMID 25581126 DOI: 10.1002/Smll.201402859  0.812
2015 Chiu HW, Xia T, Lee YH, Chen CW, Tsai JC, Wang YJ. Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress. Nanoscale. 7: 736-46. PMID 25429417 DOI: 10.1039/C4Nr05509H  0.42
2015 Low-Kam C, Telesca D, Ji Z, Zhang H, Xia T, Zink JI, Nel AE. A bayesian regression tree approach to identify the effect of nanoparticles’ properties on toxicity profiles Annals of Applied Statistics. 9: 383-401. DOI: 10.1214/14-Aoas797  0.745
2014 Li R, Ji Z, Qin H, Kang X, Sun B, Wang M, Chang CH, Wang X, Zhang H, Zou H, Nel AE, Xia T. Interference in autophagosome fusion by rare earth nanoparticles disrupts autophagic flux and regulation of an interleukin-1β producing inflammasome. Acs Nano. 8: 10280-92. PMID 25251502 DOI: 10.1021/Nn505002W  0.825
2014 Chen Y, Wang Z, Xu M, Wang X, Liu R, Liu Q, Zhang Z, Xia T, Zhao J, Jiang G, Xu Y, Liu S. Nanosilver incurs an adaptive shunt of energy metabolism mode to glycolysis in tumor and nontumor cells. Acs Nano. 8: 5813-25. PMID 24810997 DOI: 10.1021/Nn500719M  0.411
2014 Patel T, Telesca D, Low-Kam C, Ji Z, Zhang H, Xia T, Zinc JI, Nel AE. Relating Nanoparticle Properties to Biological Outcomes in Exposure Escalation Experiments. Environmetrics. 25: 57-68. PMID 24764692 DOI: 10.1002/Env.2246  0.652
2014 Lin S, Wang X, Ji Z, Chang CH, Dong Y, Meng H, Liao YP, Wang M, Song TB, Kohan S, Xia T, Zink JI, Lin S, Nel AE. Aspect ratio plays a role in the hazard potential of CeO2 nanoparticles in mouse lung and zebrafish gastrointestinal tract. Acs Nano. 8: 4450-64. PMID 24720650 DOI: 10.1021/Nn5012754  0.82
2014 Zhang H, Pokhrel S, Ji Z, Meng H, Wang X, Lin S, Chang CH, Li L, Li R, Sun B, Wang M, Liao YP, Liu R, Xia T, Mädler L, et al. PdO doping tunes band-gap energy levels as well as oxidative stress responses to a Co₃O₄ p-type semiconductor in cells and the lung. Journal of the American Chemical Society. 136: 6406-20. PMID 24673286 DOI: 10.1021/Ja501699E  0.811
2014 Li R, Ji Z, Chang CH, Dunphy DR, Cai X, Meng H, Zhang H, Sun B, Wang X, Dong J, Lin S, Wang M, Liao YP, Brinker CJ, Nel A, ... Xia T, et al. Surface interactions with compartmentalized cellular phosphates explain rare earth oxide nanoparticle hazard and provide opportunities for safer design. Acs Nano. 8: 1771-83. PMID 24417322 DOI: 10.1021/Nn406166N  0.823
2014 Liu R, France B, George S, Rallo R, Zhang H, Xia T, Nel AE, Bradley K, Cohen Y. Association rule mining of cellular responses induced by metal and metal oxide nanoparticles. The Analyst. 139: 943-53. PMID 24260774 DOI: 10.1039/C3An01409F  0.808
2014 Wang X, Ji Z, Chang CH, Zhang H, Wang M, Liao YP, Lin S, Meng H, Li R, Sun B, Winkle LV, Pinkerton KE, Zink JI, Xia T, Nel AE. Use of coated silver nanoparticles to understand the relationship of particle dissolution and bioavailability to cell and lung toxicological potential. Small (Weinheim An Der Bergstrasse, Germany). 10: 385-98. PMID 24039004 DOI: 10.1002/Smll.201301597  0.808
2014 Lu B, Smith T, Li R, Xia T, Nel A, Schmidt J. Nanoparticle-Membrane Interactions Studied with Lipid Bilayer Arrays Biophysical Journal. 106: 415a. DOI: 10.1016/J.Bpj.2013.11.2336  0.736
2013 Patel T, Telesca D, Rallo R, George S, Xia T, Nel AE. Hierarchical Rank Aggregation with Applications to Nanotoxicology. Journal of Agricultural, Biological, and Environmental Statistics. 18: 159-177. PMID 24839387 DOI: 10.1007/S13253-013-0129-Y  0.746
2013 Sun B, Ji Z, Liao YP, Wang M, Wang X, Dong J, Chang CH, Li R, Zhang H, Nel AE, Xia T. Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles. Acs Nano. 7: 10834-49. PMID 24261790 DOI: 10.1021/Nn404211J  0.804
2013 Qu G, Liu S, Zhang S, Wang L, Wang X, Sun B, Yin N, Gao X, Xia T, Chen JJ, Jiang GB. Graphene oxide induces toll-like receptor 4 (TLR4)-dependent necrosis in macrophages. Acs Nano. 7: 5732-45. PMID 23734789 DOI: 10.1021/Nn402330B  0.618
2013 Liu R, Zhang HY, Ji ZX, Rallo R, Xia T, Chang CH, Nel A, Cohen Y. Development of structure-activity relationship for metal oxide nanoparticles. Nanoscale. 5: 5644-53. PMID 23689214 DOI: 10.1039/C3Nr01533E  0.655
2013 Xia T, Hamilton RF, Bonner JC, Crandall ED, Elder A, Fazlollahi F, Girtsman TA, Kim K, Mitra S, Ntim SA, Orr G, Tagmount M, Taylor AJ, Telesca D, Tolic A, et al. Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium. Environmental Health Perspectives. 121: 683-90. PMID 23649538 DOI: 10.1289/Ehp.1306561  0.692
2013 Wang Z, Liu S, Ma J, Qu G, Wang X, Yu S, He J, Liu J, Xia T, Jiang GB. Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells. Acs Nano. 7: 4171-86. PMID 23570347 DOI: 10.1021/Nn400594S  0.34
2013 Li R, Wang X, Ji Z, Sun B, Zhang H, Chang CH, Lin S, Meng H, Liao YP, Wang M, Li Z, Hwang AA, Song TB, Xu R, Yang Y, ... ... Xia T, et al. Surface charge and cellular processing of covalently functionalized multiwall carbon nanotubes determine pulmonary toxicity. Acs Nano. 7: 2352-68. PMID 23414138 DOI: 10.1021/Nn305567S  0.803
2013 Meng H, Mai WX, Zhang H, Xue M, Xia T, Lin S, Wang X, Zhao Y, Ji Z, Zink JI, Nel AE. Codelivery of an optimal drug/siRNA combination using mesoporous silica nanoparticles to overcome drug resistance in breast cancer in vitro and in vivo. Acs Nano. 7: 994-1005. PMID 23289892 DOI: 10.1021/Nn3044066  0.784
2013 Lin S, Zhao Y, Ji Z, Ear J, Chang CH, Zhang H, Low-Kam C, Yamada K, Meng H, Wang X, Liu R, Pokhrel S, Mädler L, Damoiseaux R, Xia T, et al. Zebrafish high-throughput screening to study the impact of dissolvable metal oxide nanoparticles on the hatching enzyme, ZHE1. Small (Weinheim An Der Bergstrasse, Germany). 9: 1776-85. PMID 23180726 DOI: 10.1002/Smll.201202128  0.813
2013 Sun B, Wang X, Ji Z, Li R, Xia T. NLRP3 inflammasome activation induced by engineered nanomaterials. Small (Weinheim An Der Bergstrasse, Germany). 9: 1595-607. PMID 23180683 DOI: 10.1002/Smll.201201962  0.747
2013 Xia T, Malasarn D, Lin S, Ji Z, Zhang H, Miller RJ, Keller AA, Nisbet RM, Harthorn BH, Godwin HA, Lenihan HS, Liu R, Gardea-Torresdey J, Cohen Y, Mädler L, et al. Implementation of a multidisciplinary approach to solve complex nano EHS problems by the UC Center for the Environmental Implications of Nanotechnology. Small (Weinheim An Der Bergstrasse, Germany). 9: 1428-43. PMID 23027589 DOI: 10.1002/Smll.201201700  0.782
2013 Zhu M, Nie G, Meng H, Xia T, Nel A, Zhao Y. Physicochemical properties determine nanomaterial cellular uptake, transport, and fate. Accounts of Chemical Research. 46: 622-31. PMID 22891796 DOI: 10.1021/Ar300031Y  0.726
2013 Nel A, Xia T, Meng H, Wang X, Lin S, Ji Z, Zhang H. Nanomaterial toxicity testing in the 21st century: use of a predictive toxicological approach and high-throughput screening. Accounts of Chemical Research. 46: 607-21. PMID 22676423 DOI: 10.1021/Ar300022H  0.801
2013 Sun B, Li R, Wang X, Xia T. Predictive toxicological paradigm and high throughput approach for toxicity screening of engineered nanomaterials International Journal of Biomedical Nanoscience and Nanotechnology. 3: 4. DOI: 10.1504/Ijbnn.2013.054506  0.739
2013 Lin S, Zhao Y, Ji Z, Ear J, Chang CH, Zhang H, Low-Kam C, Yamada K, Meng H, Wang X, Liu R, Pokhrel S, Mädler L, Damoiseaux R, Xia T, et al. Metal Oxides: Zebrafish High-Throughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1 (Small 9-10/2013) Small. 9: 1775-1775. DOI: 10.1002/Smll.201370059  0.782
2012 Zhang H, Dunphy DR, Jiang X, Meng H, Sun B, Tarn D, Xue M, Wang X, Lin S, Ji Z, Li R, Garcia FL, Yang J, Kirk ML, Xia T, et al. Processing pathway dependence of amorphous silica nanoparticle toxicity: colloidal vs pyrolytic. Journal of the American Chemical Society. 134: 15790-804. PMID 22924492 DOI: 10.1021/Ja304907C  0.811
2012 Gilbert B, Fakra SC, Xia T, Pokhrel S, Mädler L, Nel AE. The fate of ZnO nanoparticles administered to human bronchial epithelial cells. Acs Nano. 6: 4921-30. PMID 22646753 DOI: 10.1021/Nn300425A  0.676
2012 Ji Z, Wang X, Zhang H, Lin S, Meng H, Sun B, George S, Xia T, Nel AE, Zink JI. Designed synthesis of CeO2 nanorods and nanowires for studying toxicological effects of high aspect ratio nanomaterials. Acs Nano. 6: 5366-80. PMID 22564147 DOI: 10.1021/Nn3012114  0.799
2012 Wang X, Xia T, Duch MC, Ji Z, Zhang H, Li R, Sun B, Lin S, Meng H, Liao YP, Wang M, Song TB, Yang Y, Hersam MC, Nel AE. Pluronic F108 coating decreases the lung fibrosis potential of multiwall carbon nanotubes by reducing lysosomal injury. Nano Letters. 12: 3050-61. PMID 22546002 DOI: 10.1021/Nl300895Y  0.787
2012 Liu R, Lin S, Rallo R, Zhao Y, Damoiseaux R, Xia T, Lin S, Nel A, Cohen Y. Automated phenotype recognition for zebrafish embryo based in vivo high throughput toxicity screening of engineered nano-materials. Plos One. 7: e35014. PMID 22506062 DOI: 10.1371/Journal.Pone.0035014  0.722
2012 Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, et al. Use of metal oxide nanoparticle band gap to develop a predictive paradigm for oxidative stress and acute pulmonary inflammation. Acs Nano. 6: 4349-68. PMID 22502734 DOI: 10.1021/Nn3010087  0.806
2012 George S, Lin S, Ji Z, Thomas CR, Li L, Mecklenburg M, Meng H, Wang X, Zhang H, Xia T, Hohman JN, Lin S, Zink JI, Weiss PS, Nel AE. Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos. Acs Nano. 6: 3745-59. PMID 22482460 DOI: 10.1021/Nn204671V  0.806
2011 Wang X, Xia T, Ntim SA, Ji Z, Lin S, Meng H, Chung CH, George S, Zhang H, Wang M, Li N, Yang Y, Castranova V, Mitra S, Bonner JC, et al. Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung. Acs Nano. 5: 9772-87. PMID 22047207 DOI: 10.1021/Nn2033055  0.799
2011 Lin S, Zhao Y, Xia T, Meng H, Ji Z, Liu R, George S, Xiong S, Wang X, Zhang H, Pokhrel S, Mädler L, Damoiseaux R, Lin S, Nel AE. High content screening in zebrafish speeds up hazard ranking of transition metal oxide nanoparticles. Acs Nano. 5: 7284-95. PMID 21851096 DOI: 10.1021/Nn202116P  0.791
2011 George S, Pokhrel S, Ji Z, Henderson BL, Xia T, Li L, Zink JI, Nel AE, Mädler L. Role of Fe doping in tuning the band gap of TiO2 for the photo-oxidation-induced cytotoxicity paradigm. Journal of the American Chemical Society. 133: 11270-8. PMID 21678906 DOI: 10.1021/Ja202836S  0.763
2011 Meng H, Yang S, Li Z, Xia T, Chen J, Ji Z, Zhang H, Wang X, Lin S, Huang C, Zhou ZH, Zink JI, Nel AE. Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism. Acs Nano. 5: 4434-47. PMID 21563770 DOI: 10.1021/Nn103344K  0.801
2011 Meng H, Xue M, Xia T, Ji Z, Tarn DY, Zink JI, Nel AE. Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica nanoparticles in a murine xenograft tumor model. Acs Nano. 5: 4131-44. PMID 21524062 DOI: 10.1021/Nn200809T  0.731
2011 Zhang H, Xia T, Meng H, Xue M, George S, Ji Z, Wang X, Liu R, Wang M, France B, Rallo R, Damoiseaux R, Cohen Y, Bradley KA, Zink JI, et al. Differential expression of syndecan-1 mediates cationic nanoparticle toxicity in undifferentiated versus differentiated normal human bronchial epithelial cells. Acs Nano. 5: 2756-69. PMID 21366263 DOI: 10.1021/Nn200328M  0.808
2011 George S, Xia T, Rallo R, Zhao Y, Ji Z, Lin S, Wang X, Zhang H, France B, Schoenfeld D, Damoiseaux R, Liu R, Lin S, Bradley KA, Cohen Y, et al. Use of a high-throughput screening approach coupled with in vivo zebrafish embryo screening to develop hazard ranking for engineered nanomaterials. Acs Nano. 5: 1805-17. PMID 21323332 DOI: 10.1021/Nn102734S  0.801
2011 Damoiseaux R, George S, Li M, Pokhrel S, Ji Z, France B, Xia T, Suarez E, Rallo R, Mädler L, Cohen Y, Hoek EM, Nel A. No time to lose--high throughput screening to assess nanomaterial safety. Nanoscale. 3: 1345-60. PMID 21301704 DOI: 10.1039/C0Nr00618A  0.741
2011 Thomas CR, George S, Horst AM, Ji Z, Miller RJ, Peralta-Videa JR, Xia T, Pokhrel S, Mädler L, Gardea-Torresdey JL, Holden PA, Keller AA, Lenihan HS, Nel AE, Zink JI. Nanomaterials in the environment: from materials to high-throughput screening to organisms. Acs Nano. 5: 13-20. PMID 21261306 DOI: 10.1021/Nn1034857  0.759
2011 Xia T, Zhao Y, Sager T, George S, Pokhrel S, Li N, Schoenfeld D, Meng H, Lin S, Wang X, Wang M, Ji Z, Zink JI, Mädler L, Castranova V, et al. Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos. Acs Nano. 5: 1223-35. PMID 21250651 DOI: 10.1021/Nn1028482  0.804
2011 Roebben G, Ramirez-Garcia S, Hackley VA, Roesslein M, Klaessig F, Kestens V, Lynch I, Garner CM, Rawle A, Elder A, Colvin VL, Kreyling W, Krug HF, Lewicka ZA, McNeil S, ... ... Xia T, et al. Interlaboratory comparison of size and surface charge measurements on nanoparticles prior to biological impact assessment Journal of Nanoparticle Research. 13: 2675-2687. DOI: 10.1007/S11051-011-0423-Y  0.654
2010 Wang X, Xia T, Ntim SA, Ji Z, George S, Meng H, Zhang H, Castranova V, Mitra S, Nel AE. Quantitative techniques for assessing and controlling the dispersion and biological effects of multiwalled carbon nanotubes in mammalian tissue culture cells. Acs Nano. 4: 7241-52. PMID 21067152 DOI: 10.1021/Nn102112B  0.791
2010 Meng H, Liong M, Xia T, Li Z, Ji Z, Zink JI, Nel AE. Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line. Acs Nano. 4: 4539-50. PMID 20731437 DOI: 10.1021/Nn100690M  0.712
2010 Meng H, Xue M, Xia T, Zhao YL, Tamanoi F, Stoddart JF, Zink JI, Nel AE. Autonomous in vitro anticancer drug release from mesoporous silica nanoparticles by pH-sensitive nanovalves. Journal of the American Chemical Society. 132: 12690-7. PMID 20718462 DOI: 10.1021/Ja104501A  0.732
2010 Ji Z, Jin X, George S, Xia T, Meng H, Wang X, Suarez E, Zhang H, Hoek EM, Godwin H, Nel AE, Zink JI. Dispersion and stability optimization of TiO2 nanoparticles in cell culture media. Environmental Science & Technology. 44: 7309-14. PMID 20536146 DOI: 10.1021/Es100417S  0.808
2010 George S, Pokhrel S, Xia T, Gilbert B, Ji Z, Schowalter M, Rosenauer A, Damoiseaux R, Bradley KA, Mädler L, Nel AE. Use of a rapid cytotoxicity screening approach to engineer a safer zinc oxide nanoparticle through iron doping. Acs Nano. 4: 15-29. PMID 20043640 DOI: 10.1021/Nn901503Q  0.789
2009 Meng H, Xia T, George S, Nel AE. A predictive toxicological paradigm for the safety assessment of nanomaterials. Acs Nano. 3: 1620-7. PMID 21452863 DOI: 10.1021/Nn9005973  0.784
2009 Kovochich M, Espinasse B, Auffan M, Hotze EM, Wessel L, Xia T, Nel AE, Wiesner MR. Comparative toxicity of C60 aggregates toward mammalian cells: role of tetrahydrofuran (THF) decomposition. Environmental Science & Technology. 43: 6378-84. PMID 19746740 DOI: 10.1021/Es900990D  0.661
2009 Xia T, Kovochich M, Liong M, Meng H, Kabehie S, George S, Zink JI, Nel AE. Polyethyleneimine coating enhances the cellular uptake of mesoporous silica nanoparticles and allows safe delivery of siRNA and DNA constructs. Acs Nano. 3: 3273-86. PMID 19739605 DOI: 10.1021/Nn900918W  0.802
2009 Xia T, Li N, Nel AE. Potential health impact of nanoparticles. Annual Review of Public Health. 30: 137-50. PMID 19705557 DOI: 10.1146/Annurev.Publhealth.031308.100155  0.638
2009 Nel AE, Mädler L, Velegol D, Xia T, Hoek EM, Somasundaran P, Klaessig F, Castranova V, Thompson M. Understanding biophysicochemical interactions at the nano-bio interface. Nature Materials. 8: 543-57. PMID 19525947 DOI: 10.1038/Nmat2442  0.653
2009 Meng H, Xia T, George S, Nel AE. Reply to “Assessing the Safety of Nanomaterials by Genomic Approach Could Be Another Alternative” Acs Nano. 3: 3830-3831. DOI: 10.1021/Nn901576J  0.755
2009 Pokhrel S, Xia T, Kovochich M, Liong M, Schowalter M, Rosenauer A, Gilbert B, Zink J, Nel A, Mädler L. Comparison of the mechanism of toxicity of binary and mixed binary metal oxide nanoparticles based on dissolution and oxidative stress properties Chemie Ingenieur Technik. 81: 1167-1167. DOI: 10.1002/Cite.200950629  0.639
2008 Xia T, Kovochich M, Liong M, Zink JI, Nel AE. Cationic polystyrene nanosphere toxicity depends on cell-specific endocytic and mitochondrial injury pathways. Acs Nano. 2: 85-96. PMID 19206551 DOI: 10.1021/Nn700256C  0.654
2008 Liong M, Lu J, Kovochich M, Xia T, Ruehm SG, Nel AE, Tamanoi F, Zink JI. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. Acs Nano. 2: 889-96. PMID 19206485 DOI: 10.1021/Nn800072T  0.645
2008 Xia T, Kovochich M, Liong M, Mädler L, Gilbert B, Shi H, Yeh JI, Zink JI, Nel AE. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. Acs Nano. 2: 2121-34. PMID 19206459 DOI: 10.1021/Nn800511K  0.684
2008 Xia T, Rome L, Nel A. Nanobiology: particles slip cell security. Nature Materials. 7: 519-20. PMID 18574478 DOI: 10.1038/Nmat2213  0.637
2008 Li N, Xia T, Nel AE. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Radical Biology & Medicine. 44: 1689-99. PMID 18313407 DOI: 10.1016/J.Freeradbiomed.2008.01.028  0.662
2007 Lu J, Liong M, Sherman S, Xia T, Kovochich M, Nel AE, Zink JI, Tamanoi F. Mesoporous Silica Nanoparticles for Cancer Therapy: Energy-Dependent Cellular Uptake and Delivery of Paclitaxel to Cancer Cells. Nanobiotechnology : the Journal At the Intersection of Nanotechnology, Molecular Biology, and Biomedical Sciences. 3: 89-95. PMID 19936038 DOI: 10.1007/S12030-008-9003-3  0.654
2007 Shi H, Xia T, Nel AE, Yeh JI. Part II: coordinated biosensors--development of enhanced nanobiosensors for biological and medical applications. Nanomedicine (London, England). 2: 599-614. PMID 17976023 DOI: 10.2217/17435889.2.5.599  0.595
2007 Xia T, Kovochich M, Nel AE. Impairment of mitochondrial function by particulate matter (PM) and their toxic components: implications for PM-induced cardiovascular and lung disease. Frontiers in Bioscience : a Journal and Virtual Library. 12: 1238-46. PMID 17127377 DOI: 10.2741/2142  0.618
2006 Xia T, Kovochich M, Nel A. The role of reactive oxygen species and oxidative stress in mediating particulate matter injury. Clinics in Occupational and Environmental Medicine. 5: 817-36. PMID 17110294 DOI: 10.1016/J.Coem.2006.07.005  0.614
2006 Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, Sioutas C, Yeh JI, Wiesner MR, Nel AE. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano Letters. 6: 1794-807. PMID 16895376 DOI: 10.1021/Nl061025K  0.685
2006 Nel A, Xia T, Mädler L, Li N. Toxic potential of materials at the nanolevel. Science (New York, N.Y.). 311: 622-7. PMID 16456071 DOI: 10.1126/Science.1114397  0.628
2004 Xia T, Korge P, Weiss JN, Li N, Venkatesen MI, Sioutas C, Nel A. Quinones and aromatic chemical compounds in particulate matter induce mitochondrial dysfunction: implications for ultrafine particle toxicity. Environmental Health Perspectives. 112: 1347-58. PMID 15471724 DOI: 10.1289/Ehp.7167  0.621
2002 Xia T, Jiang C, Li L, Wu C, Chen Q, Liu SS. A study on permeability transition pore opening and cytochrome c release from mitochondria, induced by caspase-3 in vitro. Febs Letters. 510: 62-6. PMID 11755532 DOI: 10.1016/S0014-5793(01)03228-8  0.635
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