Year |
Citation |
Score |
2024 |
Chen S, Puri A, Bell B, Fritsche J, Palacios HH, Balch M, Sprunger ML, Howard MK, Ryan JJ, Haines JN, Patti GJ, Davis AA, Jackrel ME. HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species. Nature Communications. 15: 2436. PMID 38499535 DOI: 10.1038/s41467-024-46538-8 |
0.693 |
|
2023 |
Shrimali PC, Chen S, Das A, Dreher R, Howard MK, Ryan JJ, Buck J, Kim D, Sprunger ML, Rudra JS, Jackrel ME. Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines. Acta Biomaterialia. PMID 37586449 DOI: 10.1016/j.actbio.2023.08.015 |
0.648 |
|
2023 |
Howard MK, Miller KR, Sohn BS, Ryan JJ, Xu A, Jackrel ME. Probing the drivers of biofilm protein amyloidogenesis and disrupting biofilms with engineered protein disaggregases. Mbio. e0058723. PMID 37195208 DOI: 10.1128/mbio.00587-23 |
0.741 |
|
2021 |
Ryan JJ, Bao A, Bell B, Ling C, Jackrel ME. Drivers of Hsp104 potentiation revealed by scanning mutagenesis of the middle domain. Protein Science : a Publication of the Protein Society. PMID 34010483 DOI: 10.1002/pro.4126 |
0.689 |
|
2020 |
Ryan J, Bao A, Bell B, Jackrel M. Mechanistic Insights into Potentiation of the AAA+ Disaggregase Hsp104 Biophysical Journal. 118: 337a. DOI: 10.1016/J.Bpj.2019.11.1880 |
0.654 |
|
2019 |
Ryan JJ, Sprunger ML, Holthaus K, Shorter J, Jackrel ME. Correction: Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. The Journal of Biological Chemistry. 294: 17707. PMID 31732685 DOI: 10.1074/jbc.AAC119.011523 |
0.654 |
|
2019 |
Ryan JJ, Sprunger ML, Holthaus K, Shorter J, Jackrel ME. Engineered protein disaggregases mitigate toxicity of aberrant prion-like fusion proteins underlying sarcoma. The Journal of Biological Chemistry. PMID 31171724 DOI: 10.1074/Jbc.Ra119.009494 |
0.675 |
|
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