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Leighton J. Core, Ph.D. - Publications

Affiliations: 
University of Connecticut, Storrs, CT, United States 
Area:
Transcription, Genomics
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Pelham-Webb B, Polyzos A, Wojenski L, Kloetgen A, Li J, Di Giammartino DC, Sakellaropoulos T, Tsirigos A, Core L, Apostolou E. H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization. Molecular Cell. PMID 33730542 DOI: 10.1016/j.molcel.2021.02.032  0.345
2019 Sathyan KM, McKenna BD, Anderson WD, Duarte FM, Core L, Guertin MJ. An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion. Genes & Development. PMID 31467088 DOI: 10.1101/Gad.328237.119  0.688
2019 Core L, Adelman K. Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation. Genes & Development. PMID 31123063 DOI: 10.1101/Gad.325142.119  0.584
2019 Hsiao JS, Germain ND, Wilderman A, Stoddard C, Wojenski LA, Villafano GJ, Core L, Cotney J, Chamberlain SJ. A bipartite boundary element restricts imprinting to mature neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674673 DOI: 10.1073/Pnas.1815279116  0.33
2019 Zhang Z, Chng K, Lingadahalli S, Chen Z, Liu MH, Do HH, Cai S, Rinaldi N, Poh HM, Li G, Sung Y, Heng CL, Core LJ, Tan SK, Ruan XA, et al. An AR-ERG transcriptional signature defined by long range chromatin interactomes in prostate cancer cells. Genome Research. PMID 30606742 DOI: 10.1101/Gr.230243.117  0.625
2018 Chu T, Rice EJ, Booth GT, Salamanca HH, Wang Z, Core LJ, Longo SL, Corona RJ, Chin LS, Lis JT, Kwak H, Danko CG. Chromatin run-on and sequencing maps the transcriptional regulatory landscape of glioblastoma multiforme. Nature Genetics. PMID 30349114 DOI: 10.1038/S41588-018-0244-3  0.768
2018 Lloret-Llinares M, Karadoulama E, Chen Y, Wojenski LA, Villafano GJ, Bornholdt J, Andersson R, Core L, Sandelin A, Jensen TH. The RNA exosome contributes to gene expression regulation during stem cell differentiation. Nucleic Acids Research. PMID 30212902 DOI: 10.1093/Nar/Gky817  0.555
2016 Duarte FM, Fuda NJ, Mahat DB, Core LJ, Guertin MJ, Lis JT. Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation. Genes & Development. PMID 27492368 DOI: 10.1101/Gad.284430.116  0.802
2016 Mahat DB, Kwak H, Booth GT, Jonkers IH, Danko CG, Patel RK, Waters CT, Munson K, Core LJ, Lis JT. Base-pair-resolution genome-wide mapping of active RNA polymerases using precision nuclear run-on (PRO-seq). Nature Protocols. 11: 1455-1476. PMID 27442863 DOI: 10.1038/Nprot.2016.086  0.741
2015 Andersson R, Chen Y, Core L, Lis JT, Sandelin A, Jensen TH. Human Gene Promoters Are Intrinsically Bidirectional. Molecular Cell. 60: 346-7. PMID 26545074 DOI: 10.1016/J.Molcel.2015.10.015  0.479
2015 Danko CG, Hyland SL, Core LJ, Martins AL, Waters CT, Lee HW, Cheung VG, Kraus WL, Lis JT, Siepel A. Identification of active transcriptional regulatory elements from GRO-seq data. Nature Methods. 12: 433-8. PMID 25799441 DOI: 10.1038/Nmeth.3329  0.696
2014 Andersson R, Refsing Andersen P, Valen E, Core LJ, Bornholdt J, Boyd M, Heick Jensen T, Sandelin A. Nuclear stability and transcriptional directionality separate functionally distinct RNA species. Nature Communications. 5: 5336. PMID 25387874 DOI: 10.1038/Ncomms6336  0.549
2014 Core LJ, Martins AL, Danko CG, Waters CT, Siepel A, Lis JT. Analysis of nascent RNA identifies a unified architecture of initiation regions at mammalian promoters and enhancers. Nature Genetics. 46: 1311-20. PMID 25383968 DOI: 10.1038/Ng.3142  0.697
2014 Wang IX, Core LJ, Kwak H, Brady L, Bruzel A, McDaniel L, Richards AL, Wu M, Grunseich C, Lis JT, Cheung VG. RNA-DNA differences are generated in human cells within seconds after RNA exits polymerase II. Cell Reports. 6: 906-15. PMID 24561252 DOI: 10.1016/J.Celrep.2014.01.037  0.728
2014 Maxwell CS, Kruesi WS, Core LJ, Kurhanewicz N, Waters CT, Lewarch CL, Antoshechkin I, Lis JT, Meyer BJ, Baugh LR. Pol II docking and pausing at growth and stress genes in C. elegans. Cell Reports. 6: 455-66. PMID 24485661 DOI: 10.1016/J.Celrep.2014.01.008  0.698
2013 Kilpinen H, Waszak SM, Gschwind AR, Raghav SK, Witwicki RM, Orioli A, Migliavacca E, Wiederkehr M, Gutierrez-Arcelus M, Panousis NI, Yurovsky A, Lappalainen T, Romano-Palumbo L, Planchon A, Bielser D, ... ... Core LJ, et al. Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. Science (New York, N.Y.). 342: 744-7. PMID 24136355 DOI: 10.1126/Science.1242463  0.643
2013 Kruesi WS, Core LJ, Waters CT, Lis JT, Meyer BJ. Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation. Elife. 2: e00808. PMID 23795297 DOI: 10.7554/Elife.00808  0.68
2013 Saunders A, Core LJ, Sutcliffe C, Lis JT, Ashe HL. Extensive polymerase pausing during Drosophila axis patterning enables high-level and pliable transcription. Genes & Development. 27: 1146-58. PMID 23699410 DOI: 10.1101/Gad.215459.113  0.776
2013 Danko CG, Hah N, Luo X, Martins AL, Core L, Lis JT, Siepel A, Kraus WL. Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells. Molecular Cell. 50: 212-22. PMID 23523369 DOI: 10.1016/J.Molcel.2013.05.025  0.707
2013 Kwak H, Fuda NJ, Core LJ, Lis JT. Precise maps of RNA polymerase reveal how promoters direct initiation and pausing. Science (New York, N.Y.). 339: 950-3. PMID 23430654 DOI: 10.1126/Science.1229386  0.798
2013 Kruesi WS, Core LJ, Waters CT, Lis JT, Meyer BJ. Author response: Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation Elife. DOI: 10.7554/Elife.00808.042  0.604
2012 Core LJ, Waterfall JJ, Gilchrist DA, Fargo DC, Kwak H, Adelman K, Lis JT. Defining the status of RNA polymerase at promoters. Cell Reports. 2: 1025-35. PMID 23062713 DOI: 10.1016/J.Celrep.2012.08.034  0.798
2012 Fuda NJ, Buckley MS, Wei W, Core LJ, Waters CT, Reinberg D, Lis JT. Fcp1 dephosphorylation of the RNA polymerase II C-terminal domain is required for efficient transcription of heat shock genes. Molecular and Cellular Biology. 32: 3428-37. PMID 22733996 DOI: 10.1128/Mcb.00247-12  0.772
2012 Diaz AR, Core LJ, Jiang M, Morelli M, Chiang CH, Szurmant H, Perego M. Bacillus subtilis RapA phosphatase domain interaction with its substrate, phosphorylated Spo0F, and its inhibitor, the PhrA peptide. Journal of Bacteriology. 194: 1378-88. PMID 22267516 DOI: 10.1128/Jb.06747-11  0.311
2011 Chopra VS, Hendrix DA, Core LJ, Tsui C, Lis JT, Levine M. The polycomb group mutant esc leads to augmented levels of paused Pol II in the Drosophila embryo. Molecular Cell. 42: 837-44. PMID 21700228 DOI: 10.1016/J.Molcel.2011.05.009  0.68
2011 Hah N, Danko CG, Core L, Waterfall JJ, Siepel A, Lis JT, Kraus WL. A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells. Cell. 145: 622-34. PMID 21549415 DOI: 10.1016/J.Cell.2011.03.042  0.658
2011 Min IM, Waterfall JJ, Core LJ, Munroe RJ, Schimenti J, Lis JT. Regulating RNA polymerase pausing and transcription elongation in embryonic stem cells. Genes & Development. 25: 742-54. PMID 21460038 DOI: 10.1101/Gad.2005511  0.756
2011 Larschan E, Bishop EP, Kharchenko PV, Core LJ, Lis JT, Park PJ, Kuroda MI. X chromosome dosage compensation via enhanced transcriptional elongation in Drosophila. Nature. 471: 115-8. PMID 21368835 DOI: 10.1038/Nature09757  0.66
2011 Hah N, Danko CG, Core L, Waterfall JJ, Siepel A, Lis JT, Kraus WL. Erratum: A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells (Cell (2011) 145 (622-634)) Cell. 145. DOI: 10.1016/J.Cell.2011.06.003  0.529
2009 Core LJ, Lis JT. Paused Pol II captures enhancer activity and acts as a potent insulator. Genes & Development. 23: 1606-12. PMID 19605681 DOI: 10.1101/Gad.1827709  0.662
2009 Seila AC, Core LJ, Lis JT, Sharp PA. Divergent transcription: a new feature of active promoters. Cell Cycle (Georgetown, Tex.). 8: 2557-64. PMID 19597342 DOI: 10.4161/Cc.8.16.9305  0.734
2009 Kininis M, Isaacs GD, Core LJ, Hah N, Kraus WL. Postrecruitment regulation of RNA polymerase II directs rapid signaling responses at the promoters of estrogen target genes. Molecular and Cellular Biology. 29: 1123-33. PMID 19103744 DOI: 10.1128/Mcb.00841-08  0.579
2009 Lis JT, Buckley M, Core LJ, Min IM, Petesch S, Waterfall JJ, Zobeck K. New Views of Local and Genome-wide Transcription Regulation in Vivo Journal of Genetics and Molecular Biology. 20: 90-90. DOI: 10.30047/Jgmb.200912.0017  0.733
2008 Core LJ, Waterfall JJ, Lis JT. Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science (New York, N.Y.). 322: 1845-8. PMID 19056941 DOI: 10.1126/Science.1162228  0.729
2008 Core LJ, Lis JT. Transcription regulation through promoter-proximal pausing of RNA polymerase II. Science (New York, N.Y.). 319: 1791-2. PMID 18369138 DOI: 10.1126/Science.1150843  0.742
2006 Saunders A, Core LJ, Lis JT. Breaking barriers to transcription elongation. Nature Reviews. Molecular Cell Biology. 7: 557-67. PMID 16936696 DOI: 10.1038/Nrm1981  0.813
2003 Core L, Perego M. TPR-mediated interaction of RapC with ComA inhibits response regulator-DNA binding for competence development in Bacillus subtilis Molecular Microbiology. 49: 1509-1522. PMID 12950917 DOI: 10.1046/J.1365-2958.2003.03659.X  0.353
2002 Ishikawa S, Core L, Perego M. Biochemical characterization of aspartyl phosphate phosphatase interaction with a phosphorylated response regulator and its inhibition by a pentapeptide Journal of Biological Chemistry. 277: 20483-20489. PMID 11923303 DOI: 10.1074/Jbc.M201086200  0.307
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