| Year |
Citation |
Score |
| 2023 |
Ahmed N, Ahmed N, Bilodeau DA, Pezacki JP. Author Correction: An unnatural enzyme with endonuclease activity towards small non-coding RNAs. Nature Communications. 14: 7588. PMID 37990004 DOI: 10.1038/s41467-023-43521-7 |
0.769 |
|
| 2023 |
Bilodeau DA, Margison KD, Masoud SS, Nakajima M, Pezacki JP. Mechanistic Analysis of Bioorthogonal Double Strain-Promoted Alkyne-Nitrone Cycloadditions Involving Dibenzocyclooctadiyne. Acs Chemical Biology. 18: 2430-2438. PMID 37852229 DOI: 10.1021/acschembio.3c00491 |
0.783 |
|
| 2023 |
Ahmed N, Ahmed N, Bilodeau DA, Pezacki JP. An unnatural enzyme with endonuclease activity towards small non-coding RNAs. Nature Communications. 14: 3777. PMID 37355703 DOI: 10.1038/s41467-023-39105-0 |
0.8 |
|
| 2022 |
Desrochers GF, Filip R, Bastianelli M, Stern T, Pezacki JP. microRNA-27b regulates hepatic lipase enzyme LIPC and reduces triglyceride degradation during hepatitis C virus infection. The Journal of Biological Chemistry. 101983. PMID 35483451 DOI: 10.1016/j.jbc.2022.101983 |
0.793 |
|
| 2021 |
Scinto SL, Bilodeau DA, Hincapie R, Lee W, Nguyen SS, Xu M, Am Ende CW, Finn MG, Lang K, Lin Q, Pezacki JP, Prescher JA, Robillard MS, Fox JM. Bioorthogonal chemistry. Nature Reviews. Methods Primers. 1. PMID 34585143 DOI: 10.1038/s43586-021-00028-z |
0.779 |
|
| 2021 |
Labana P, Dornan MH, Lafrenière M, Czarny TL, Brown ED, Pezacki JP, Boddy CN. Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria. Cell Chemical Biology. PMID 34293284 DOI: 10.1016/j.chembiol.2021.07.001 |
0.768 |
|
| 2021 |
Shaw TA, Powdrill MH, Sherratt AR, Garland K, Li BJ, Beauchemin AM, Pezacki JP. Reactivity of -acyl hydrazone probes with the mammalian proteome. Rsc Medicinal Chemistry. 12: 797-803. PMID 34124678 DOI: 10.1039/d1md00027f |
0.784 |
|
| 2021 |
Bilodeau DA, Margison KD, Serhan M, Pezacki JP. Bioorthogonal Reactions Utilizing Nitrones as Versatile Dipoles in Cycloaddition Reactions. Chemical Reviews. PMID 33464040 DOI: 10.1021/acs.chemrev.0c00832 |
0.777 |
|
| 2021 |
Filip R, Desrochers GF, Lefebvre DM, Reed A, Singaravelu R, Cravatt BF, Pezacki JP. Profiling of microRNA targets using activity-based protein profiling: linking enzyme activity to microRNA-185 function. Cell Chemical Biology. PMID 33450181 DOI: 10.1016/j.chembiol.2020.12.009 |
0.786 |
|
| 2020 |
Nakajima M, Bilodeau DA, Pezacki JP. Predicting reactivity for bioorthogonal cycloadditions involving nitrones. Rsc Advances. 10: 29306-29310. PMID 35521144 DOI: 10.1039/d0ra05092j |
0.771 |
|
| 2020 |
Shaw T, Ablenas C, Desrochers GF, Powdrill M, Bilodeau DA, Vincent-Rocan JF, Niu M, Monette A, Mouland A, Beauchemin AM, Pezacki JP. A bifunctional nucleoside probe for the inhibition of the human immunodeficiency virus-type 1 reverse transcriptase. Bioconjugate Chemistry. PMID 32259429 DOI: 10.1021/Acs.Bioconjchem.0C00191 |
0.763 |
|
| 2020 |
Gobeil Odai K, O'Dwyer C, Steenbergen R, Shaw TA, Renner TM, Ghorbani P, Rezaaifar M, Han S, Langlois MA, Crawley AM, Russell RS, Pezacki JP, Tyrrell DL, Fullerton MD. In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism. Viruses. 12. PMID 31963173 DOI: 10.3390/V12010108 |
0.362 |
|
| 2020 |
Bilodeau DA, Margison KD, Ahmed N, Strmiskova M, Sherratt AR, Pezacki JP. Optimized aqueous Kinugasa reactions for bioorthogonal chemistry applications. Chemical Communications (Cambridge, England). PMID 31960852 DOI: 10.1039/C9Cc09473C |
0.78 |
|
| 2019 |
Singaravelu R, Ahmed N, Quan C, Srinivasan P, Ablenas CJ, Roy DG, Pezacki JP. Conserved miRNA-183 cluster regulates the innate antiviral response. The Journal of Biological Chemistry. PMID 31694919 DOI: 10.1074/Jbc.Ra119.010858 |
0.781 |
|
| 2019 |
Ablenas C, Gidi Y, Powdrill M, Ahmed N, Shaw T, Mesko M, Götte M, Cosa G, Pezacki JP. Hepatitis C virus helicase binding and activity monitored through site-specific labeling using an expanded genetic code. Acs Infectious Diseases. PMID 31640339 DOI: 10.1021/Acsinfecdis.9B00220 |
0.778 |
|
| 2019 |
Margison K, Bilodeau DA, Mahmoudi F, Pezacki JP. Cycloadditions of trans-cyclooctenes and nitrones as tools for bioorthogonal labelling. Chembiochem : a European Journal of Chemical Biology. PMID 31617669 DOI: 10.1002/Cbic.201900627 |
0.785 |
|
| 2019 |
Özcelik D, Pezacki JP. Small Molecule Inhibition of Protein Disulfide Isomerase in Neuroblastoma Cells Induces an Oxidative Stress Response and Apoptosis Pathways. Acs Chemical Neuroscience. 10: 4068-4075. PMID 31343165 DOI: 10.1021/Acschemneuro.9B00301 |
0.335 |
|
| 2019 |
Ahmed N, Foss DV, Powdrill MH, Pezacki JP. Site-Specific Cross-Linking of a p19 Viral Suppressor of RNA Silencing Protein and Its RNA Targets Using an Expanded Genetic Code. Biochemistry. PMID 31329415 DOI: 10.1021/Acs.Biochem.9B00428 |
0.748 |
|
| 2019 |
Filip R, Shaw TA, Nishida A, Pezacki JP. Fungal natural alkaloid schizocommunin activates the aryl hydrocarbon receptor pathway. Medchemcomm. 10: 985-990. PMID 31303997 DOI: 10.1039/C9Md00138G |
0.739 |
|
| 2019 |
Foss DV, Schirle NT, MacRae IJ, Pezacki JP. Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs. Febs Open Bio. PMID 31021526 DOI: 10.1002/2211-5463.12644 |
0.34 |
|
| 2019 |
Strmiskova M, Bilodeau DA, Chigrinova M, Pezacki JP. Phenanthridine-based nitrones as substrates for strain-promoted alkyne-nitrone cycloadditions Canadian Journal of Chemistry. 97: 1-6. DOI: 10.1139/cjc-2018-0253 |
0.774 |
|
| 2018 |
Özcelik D, Seto A, Rakic B, Farzam A, Supek F, Pezacki JP. Gene Expression Profiling of Endoplasmic Reticulum Stress in Hepatitis C Virus-Containing Cells Treated with an Inhibitor of Protein Disulfide Isomerases. Acs Omega. 3: 17227-17235. PMID 30775641 DOI: 10.1021/acsomega.8b02676 |
0.752 |
|
| 2018 |
Shaw TA, Singaravelu R, Powdrill MH, Nhan J, Ahmed N, Özcelik D, Pezacki JP. MicroRNA-124 Regulates Fatty Acid and Triglyceride Homeostasis. Iscience. 10: 149-157. PMID 30528902 DOI: 10.1016/J.Isci.2018.11.028 |
0.742 |
|
| 2018 |
Ahmed N, De Graaf JF, Ahmed N, Foss DV, Delcorde J, Schultz PG, Pezacki JP. Visualization of the Delivery and Release of Small RNAs Using Genetic Code Expansion and Unnatural RNA-Binding Proteins. Bioconjugate Chemistry. PMID 30408949 DOI: 10.1021/Acs.Bioconjchem.8B00649 |
0.482 |
|
| 2018 |
Desrochers GF, Pezacki JP. ABPP and Host-Virus Interactions. Current Topics in Microbiology and Immunology. PMID 30244323 DOI: 10.1007/82_2018_139 |
0.783 |
|
| 2018 |
Desrochers GF, Cornacchia C, McKay CS, Pezacki JP. Activity-Based PIK Probes Detect Changes to Protein-Protein Inter-actions During Hepatitis C Virus Replication. Acs Infectious Diseases. PMID 29509402 DOI: 10.1021/Acsinfecdis.8B00047 |
0.814 |
|
| 2018 |
Singaravelu R, Quan C, Powdrill MH, Shaw TA, Srinivasan P, Lyn RK, Alonzi RC, Jones DM, Filip R, Russell RS, Pezacki JP. MicroRNA-7 mediates cross-talk between metabolic signaling pathways in the liver. Scientific Reports. 8: 361. PMID 29321595 DOI: 10.1038/S41598-017-18529-X |
0.775 |
|
| 2017 |
Sherratt AR, Rouleau Y, Luebbert C, Strmiskova M, Veres T, Bidawid S, Corneau N, Pezacki JP. Rapid Screening and Identification of Living Pathogenic Organisms via Optimized Bioorthogonal Non-canonical Amino Acid Tagging. Cell Chemical Biology. PMID 28757183 DOI: 10.1016/J.Chembiol.2017.06.016 |
0.763 |
|
| 2017 |
Lafreniere MA, Desrochers GF, Mekbib K, Pezacki JP. An affinity-based probe for methyltransferase enzymes based on sinefungin Canadian Journal of Chemistry. 95: 1059-1063. DOI: 10.1139/Cjc-2017-0168 |
0.776 |
|
| 2016 |
Strmiskova M, Desrochers GF, Shaw TA, Powdrill MH, Lafreniere MA, Pezacki JP. Chemical Methods for Probing Virus-Host Proteomic Interactions. Acs Infectious Diseases. 2: 773-786. PMID 27933785 DOI: 10.1021/Acsinfecdis.6B00084 |
0.771 |
|
| 2016 |
Lafreniere MA, Powdrill M, Singaravelu R, Pezacki JP. 6-hydroxydopamine inhibits the hepatitis C virus through alkylation of host and viral proteins and the induction of oxidative stress. Acs Infectious Diseases. PMID 27682680 DOI: 10.1021/Acsinfecdis.6B00098 |
0.801 |
|
| 2016 |
Powdrill MH, Desrochers GF, Singaravelu R, Pezacki JP. The role of microRNAs in metabolic interactions between viruses and their hosts. Current Opinion in Virology. 19: 71-76. PMID 27475325 DOI: 10.1016/J.Coviro.2016.07.005 |
0.787 |
|
| 2016 |
Danielson DC, Sachrajda N, Wang W, Filip R, Pezacki JP. A Novel p19 Fusion Protein as a Delivery Agent for Short-interfering RNAs. Molecular Therapy. Nucleic Acids. 5: e303. PMID 27045207 DOI: 10.1038/Mtna.2016.14 |
0.792 |
|
| 2016 |
Sherratt AR, Chigrinova M, MacKenzie DA, Rastogi NK, Ouattara MT, Pezacki AT, Pezacki JP. Dual Strain-Promoted Alkyne-Nitrone Cycloadditions for Simultaneous Labeling of Bacterial Peptidoglycans. Bioconjugate Chemistry. PMID 27017898 DOI: 10.1021/Acs.Bioconjchem.6B00063 |
0.749 |
|
| 2016 |
Desrochers GF, Sherratt AR, Blais DR, Nasheri N, Ning Z, Figeys D, Goto NK, Pezacki JP. Profiling Kinase Activity during Hepatitis C Virus Replication Using a Wortmannin Probe Acs Infectious Diseases. 1: 443-452. DOI: 10.1021/acsinfecdis.5b00083 |
0.805 |
|
| 2015 |
Singaravelu R, Desrochers GF, Srinivasan P, O'Hara S, Lyn RK, Müller R, Jones DM, Russell RS, Pezacki JP. Soraphen A: A Probe for Investigating the Role of de Novo Lipogenesis during Viral Infection. Acs Infectious Diseases. 1: 130-4. PMID 27622463 DOI: 10.1021/Acsinfecdis.5B00019 |
0.798 |
|
| 2015 |
Desrochers GF, Sherratt AR, Blais DR, Nasheri N, Ning Z, Figeys D, Goto NK, Pezacki JP. Profiling Kinase Activity during Hepatitis C Virus Replication Using a Wortmannin Probe. Acs Infectious Diseases. 1: 443-52. PMID 27617927 DOI: 10.1021/Acsinfecdis.5B00083 |
0.804 |
|
| 2015 |
Singaravelu R, O'Hara S, Jones DM, Chen R, Taylor NG, Srinivasan P, Quan C, Roy DG, Steenbergen RH, Kumar A, Lyn RK, Özcelik D, Rouleau Y, Nguyen MA, Rayner KJ, ... ... Pezacki JP, et al. MicroRNAs regulate the immunometabolic response to viral infection in the liver. Nature Chemical Biology. PMID 26479438 DOI: 10.1038/Nchembio.1940 |
0.776 |
|
| 2015 |
Nasheri N, Ning Z, Figeys D, Yao S, Goto NK, Pezacki JP. Activity-based profiling of the proteasome pathway during hepatitis C virus infection. Proteomics. PMID 26314548 DOI: 10.1002/Pmic.201500169 |
0.375 |
|
| 2015 |
Singaravelu R, Srinivasan P, Pezacki JP. Armand-Frappier Outstanding Student Award--The emerging role of 25-hydroxycholesterol in innate immunity. Canadian Journal of Microbiology. 61: 521-30. PMID 26182401 DOI: 10.1139/Cjm-2015-0292 |
0.333 |
|
| 2015 |
MacKenzie DA, Sherratt AR, Chigrinova M, Kell AJ, Pezacki JP. Bioorthogonal labelling of living bacteria using unnatural amino acids containing nitrones and a nitrone derivative of vancomycin. Chemical Communications (Cambridge, England). PMID 26151942 DOI: 10.1039/C5Cc04901F |
0.741 |
|
| 2015 |
Danielson DC, Filip R, Powdrill MH, O'Hara S, Pezacki JP. Suppressing RNA silencing with small molecules and the viral suppressor of RNA silencing protein p19. Biochemical and Biophysical Research Communications. 463: 1135-40. PMID 26079891 DOI: 10.1016/J.Bbrc.2015.06.071 |
0.783 |
|
| 2015 |
Chigrinova M, MacKenzie DA, Sherratt AR, Cheung LL, Pezacki JP. Correction: Chigrinova, M., et al. Kinugasa reactions in water: from green chemistry to bioorthogonal labelling. Molecules 2015, 20, 6959-6969. Molecules (Basel, Switzerland). 20: 8303. PMID 25961167 DOI: 10.3390/Molecules20058303 |
0.727 |
|
| 2015 |
Chigrinova M, MacKenzie DA, Sherratt AR, Cheung LL, Pezacki JP, Pezacki P. Kinugasa reactions in water: from green chemistry to bioorthogonal labelling. Molecules (Basel, Switzerland). 20: 6959-69. PMID 25913933 DOI: 10.3390/Molecules20046959 |
0.751 |
|
| 2014 |
Nasheri N, McKay CS, Fulton K, Twine S, Powdrill MH, Sherratt AR, Pezacki JP. Hydrophobic triaryl-substituted β-lactams as activity-based probes for profiling eukaryotic enzymes and host-pathogen interactions. Chembiochem : a European Journal of Chemical Biology. 15: 2195-200. PMID 25179744 DOI: 10.1002/Cbic.201402097 |
0.775 |
|
| 2014 |
MacKenzie DA, Sherratt AR, Chigrinova M, Cheung LL, Pezacki JP. Strain-promoted cycloadditions involving nitrones and alkynes--rapid tunable reactions for bioorthogonal labeling. Current Opinion in Chemical Biology. 21: 81-8. PMID 25022431 DOI: 10.1016/J.Cbpa.2014.05.023 |
0.75 |
|
| 2014 |
Lyn RK, Singaravelu R, Kargman S, O'Hara S, Chan H, Oballa R, Huang Z, Jones DM, Ridsdale A, Russell RS, Partridge AW, Pezacki JP. Stearoyl-CoA desaturase inhibition blocks formation of hepatitis C virus-induced specialized membranes. Scientific Reports. 4: 4549. PMID 25008545 DOI: 10.1038/Srep04549 |
0.363 |
|
| 2014 |
Singaravelu R, Delcorde J, Lyn RK, Steenbergen RH, Jones DM, Tyrrell DL, Russell RS, Pezacki JP. Investigating the antiviral role of cell death-inducing DFF45-like effector B in HCV replication. The Febs Journal. 281: 3751-65. PMID 24980280 DOI: 10.1111/Febs.12901 |
0.376 |
|
| 2014 |
Sherratt AR, Nasheri N, McKay CS, O'Hara S, Hunt A, Ning Z, Figeys D, Goto NK, Pezacki JP. A new chemical probe for phosphatidylinositol kinase activity. Chembiochem : a European Journal of Chemical Biology. 15: 1253-6. PMID 24850173 DOI: 10.1002/Cbic.201402155 |
0.79 |
|
| 2014 |
Singaravelu R, Russell RS, Tyrrell DL, Pezacki JP. Hepatitis C virus and microRNAs: miRed in a host of possibilities. Current Opinion in Virology. 7: 1-10. PMID 24721496 DOI: 10.1016/J.Coviro.2014.03.004 |
0.366 |
|
| 2014 |
Singaravelu R, Chen R, Lyn RK, Jones DM, O'Hara S, Rouleau Y, Cheng J, Srinivasan P, Nasheri N, Russell RS, Tyrrell DL, Pezacki JP. Hepatitis C virus induced up-regulation of microRNA-27: a novel mechanism for hepatic steatosis. Hepatology (Baltimore, Md.). 59: 98-108. PMID 23897856 DOI: 10.1002/Hep.26634 |
0.783 |
|
| 2014 |
Sherratt AR, Chigrinova M, McKay CS, Beaulieu LPB, Rouleau Y, Pezacki JP. Copper-catalysed cycloaddition reactions of nitrones and alkynes for bioorthogonal labelling of living cells Rsc Advances. 4: 46966-46969. DOI: 10.1039/C4Ra07851A |
0.774 |
|
| 2014 |
Nasheri N, McKay CS, Fulton K, Twine S, Powdrill MH, Sherratt AR, Pezacki JP. Back Cover: Hydrophobic Triaryl-Substituted β-Lactams as Activity-Based Probes for Profiling Eukaryotic Enzymes and Host-Pathogen Interactions (ChemBioChem 15/2014) Chembiochem. 15: 2316-2316. DOI: 10.1002/Cbic.201490054 |
0.775 |
|
| 2013 |
Lyn RK, Hope G, Sherratt AR, McLauchlan J, Pezacki JP. Bidirectional lipid droplet velocities are controlled by differential binding strengths of HCV core DII protein. Plos One. 8: e78065. PMID 24223760 DOI: 10.1371/Journal.Pone.0078065 |
0.769 |
|
| 2013 |
Singaravelu R, Lyn RK, Srinivasan P, Delcorde J, Steenbergen RH, Tyrrell DL, Pezacki JP. Human serum activates CIDEB-mediated lipid droplet enlargement in hepatoma cells. Biochemical and Biophysical Research Communications. 441: 447-52. PMID 24161736 DOI: 10.1016/J.Bbrc.2013.10.080 |
0.301 |
|
| 2013 |
Mazumder N, Lyn RK, Singaravelu R, Ridsdale A, Moffatt DJ, Hu CW, Tsai HR, McLauchlan J, Stolow A, Kao FJ, Pezacki JP. Fluorescence lifetime imaging of alterations to cellular metabolism by domain 2 of the hepatitis C virus core protein. Plos One. 8: e66738. PMID 23826122 DOI: 10.1371/Journal.Pone.0066738 |
0.378 |
|
| 2013 |
Chigrinova M, McKay CS, Beaulieu LP, Udachin KA, Beauchemin AM, Pezacki JP. Rearrangements and addition reactions of biarylazacyclooctynones and the implications to copper-free click chemistry. Organic & Biomolecular Chemistry. 11: 3436-41. PMID 23629512 DOI: 10.1039/C3Ob40683K |
0.712 |
|
| 2013 |
Nasheri N, Joyce M, Rouleau Y, Yang P, Yao S, Tyrrell DL, Pezacki JP. Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication. Chemistry & Biology. 20: 570-82. PMID 23601646 DOI: 10.1016/J.Chembiol.2013.03.014 |
0.793 |
|
| 2013 |
Danielson DC, Pezacki JP. Studying the RNA silencing pathway with the p19 protein. Febs Letters. 587: 1198-205. PMID 23376479 DOI: 10.1016/J.Febslet.2013.01.036 |
0.65 |
|
| 2013 |
Nasheri N, Pezacki JP, Sagan SM. Design and screening of siRNAs against highly structured RNA targets. Methods in Molecular Biology (Clifton, N.J.). 942: 69-86. PMID 23027046 DOI: 10.1007/978-1-62703-119-6_4 |
0.651 |
|
| 2012 |
Sherratt AR, Blais DR, Ghasriani H, Pezacki JP, Goto NK. Activity-based protein profiling of the Escherichia coli GlpG rhomboid protein delineates the catalytic core. Biochemistry. 51: 7794-803. PMID 22963263 DOI: 10.1021/Bi301087C |
0.758 |
|
| 2012 |
Singaravelu R, Nasheri N, Sherratt A, Pezacki JP. Systems biology methods help develop a better understanding of hepatitis C virus-induced liver injury. Hepatology (Baltimore, Md.). 56: 1-4. PMID 22430896 DOI: 10.1002/Hep.25727 |
0.74 |
|
| 2012 |
McKay CS, Chigrinova M, Blake JA, Pezacki JP. Kinetics studies of rapid strain-promoted [3 + 2]-cycloadditions of nitrones with biaryl-aza-cyclooctynone. Organic & Biomolecular Chemistry. 10: 3066-70. PMID 22398581 DOI: 10.1039/C2Ob07165G |
0.706 |
|
| 2012 |
Blais DR, Nasheri N, McKay CS, Legault MC, Pezacki JP. Activity-based protein profiling of host-virus interactions. Trends in Biotechnology. 30: 89-99. PMID 21944551 DOI: 10.1016/J.Tibtech.2011.08.001 |
0.744 |
|
| 2012 |
Legault MCB, McKay CS, Moran J, Lafreniere MA, Pezacki JP. Intramolecular cyclization and subsequent rearrangements of alkyne-tethered N-heterocyclic carbenes Tetrahedron Letters. 53: 5663-5666. DOI: 10.1016/J.Tetlet.2012.08.038 |
0.772 |
|
| 2011 |
Kennedy DC, McKay CS, Legault MC, Danielson DC, Blake JA, Pegoraro AF, Stolow A, Mester Z, Pezacki JP. Cellular consequences of copper complexes used to catalyze bioorthogonal click reactions. Journal of the American Chemical Society. 133: 17993-8001. PMID 21970470 DOI: 10.1021/Ja2083027 |
0.781 |
|
| 2011 |
McKay CS, Blake JA, Cheng J, Danielson DC, Pezacki JP. Strain-promoted cycloadditions of cyclic nitrones with cyclooctynes for labeling human cancer cells. Chemical Communications (Cambridge, England). 47: 10040-2. PMID 21829852 DOI: 10.1039/C1Cc13808A |
0.781 |
|
| 2011 |
Cheng J, Danielson DC, Nasheri N, Singaravelu R, Pezacki JP. Enhanced specificity of the viral suppressor of RNA silencing protein p19 toward sequestering of human microRNA-122. Biochemistry. 50: 7745-55. PMID 21819044 DOI: 10.1021/Bi2008273 |
0.651 |
|
| 2011 |
Pezacki JP, Blake JA, Danielson DC, Kennedy DC, Lyn RK, Singaravelu R. Chemical contrast for imaging living systems: molecular vibrations drive CARS microscopy. Nature Chemical Biology. 7: 137-45. PMID 21321552 DOI: 10.1038/Nchembio.525 |
0.624 |
|
| 2011 |
Kennedy DC, McKay CS, Tay LL, Rouleau Y, Pezacki JP. Carbon-bonded silver nanoparticles: alkyne-functionalized ligands for SERS imaging of mammalian cells. Chemical Communications (Cambridge, England). 47: 3156-8. PMID 21279194 DOI: 10.1039/C0Cc05331G |
0.76 |
|
| 2011 |
Nasheri N, Singaravelu R, Goodmurphy M, Lyn RK, Pezacki JP. Competing roles of microRNA-122 recognition elements in hepatitis C virus RNA. Virology. 410: 336-44. PMID 21185047 DOI: 10.1016/J.Virol.2010.11.015 |
0.386 |
|
| 2011 |
Moran J, McKay CS, Pezacki JP. Strain-promoted 1,3-dipolar cycloadditions of diazo compounds with cyclooctynes Canadian Journal of Chemistry. 89: 148-151. DOI: 10.1139/V10-112 |
0.719 |
|
| 2010 |
Lyn RK, Kennedy DC, Stolow A, Ridsdale A, Pezacki JP. Dynamics of lipid droplets induced by the hepatitis C virus core protein. Biochemical and Biophysical Research Communications. 399: 518-24. PMID 20678475 DOI: 10.1016/J.Bbrc.2010.07.101 |
0.366 |
|
| 2010 |
Pezacki JP, Singaravelu R, Lyn RK. Host-virus interactions during hepatitis C virus infection: a complex and dynamic molecular biosystem. Molecular Biosystems. 6: 1131-42. PMID 20549003 DOI: 10.1039/B924668C |
0.381 |
|
| 2010 |
Sagan SM, Nasheri N, Luebbert C, Pezacki JP. The efficacy of siRNAs against hepatitis C virus is strongly influenced by structure and target site accessibility. Chemistry & Biology. 17: 515-27. PMID 20534349 DOI: 10.1016/J.Chembiol.2010.04.011 |
0.687 |
|
| 2010 |
Blais DR, Lyn RK, Joyce MA, Rouleau Y, Steenbergen R, Barsby N, Zhu LF, Pegoraro AF, Stolow A, Tyrrell DL, Pezacki JP. Activity-based protein profiling identifies a host enzyme, carboxylesterase 1, which is differentially active during hepatitis C virus replication. The Journal of Biological Chemistry. 285: 25602-12. PMID 20530478 DOI: 10.1074/Jbc.M110.135483 |
0.79 |
|
| 2010 |
Singaravelu R, Blais DR, McKay CS, Pezacki JP. Activity-based protein profiling of the hepatitis C virus replication in Huh-7 hepatoma cells using a non-directed active site probe. Proteome Science. 8: 5. PMID 20181094 DOI: 10.1186/1477-5956-8-5 |
0.759 |
|
| 2010 |
McKay CS, Moran J, Pezacki JP. Nitrones as dipoles for rapid strain-promoted 1,3-dipolar cycloadditions with cyclooctynes. Chemical Communications (Cambridge, England). 46: 931-3. PMID 20107654 DOI: 10.1039/B921630H |
0.765 |
|
| 2010 |
Blais DR, Brûlotte M, Qian Y, Bélanger S, Yao SQ, Pezacki JP. Activity-based proteome profiling of hepatoma cells during hepatitis C virus replication using protease substrate probes. Journal of Proteome Research. 9: 912-23. PMID 19954226 DOI: 10.1021/Pr900788A |
0.429 |
|
| 2009 |
Lyn RK, Kennedy DC, Sagan SM, Blais DR, Rouleau Y, Pegoraro AF, Xie XS, Stolow A, Pezacki JP. Direct imaging of the disruption of hepatitis C virus replication complexes by inhibitors of lipid metabolism. Virology. 394: 130-42. PMID 19747705 DOI: 10.1016/J.Virol.2009.08.022 |
0.811 |
|
| 2009 |
Kennedy DC, Tay LL, Lyn RK, Rouleau Y, Hulse J, Pezacki JP. Nanoscale aggregation of cellular beta2-adrenergic receptors measured by plasmonic interactions of functionalized nanoparticles. Acs Nano. 3: 2329-39. PMID 19702324 DOI: 10.1021/Nn900488U |
0.747 |
|
| 2009 |
van der Wiel IM, Cheng J, Koukiekolo R, Lyn RK, Stevens N, O'Connor N, Turro NJ, Pezacki JP. FLEth RNA intercalating probe is a convenient reporter for small interfering RNAs. Journal of the American Chemical Society. 131: 9872-3. PMID 19583254 DOI: 10.1021/Ja902636M |
0.318 |
|
| 2009 |
Koukiekolo R, Jakubek ZJ, Cheng J, Sagan SM, Pezacki JP. Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: a FRET-based probe for sensing double-stranded fluorophore tagged small RNAs. Biophysical Chemistry. 143: 166-9. PMID 19491057 DOI: 10.1016/J.Bpc.2009.05.001 |
0.674 |
|
| 2009 |
Cheng J, Koukiekolo R, Kieliszkiewicz K, Sagan SM, Pezacki JP. Cysteine residues of Carnation Italian Ringspot virus p19 suppressor of RNA silencing maintain global structural integrity and stability for siRNA binding. Biochimica Et Biophysica Acta. 1794: 1197-203. PMID 19341824 DOI: 10.1016/J.Bbapap.2009.03.012 |
0.684 |
|
| 2009 |
Vobornik D, Rouleau Y, Haley J, Bani-Yaghoub M, Taylor R, Johnston LJ, Pezacki JP. Nanoscale organization of beta2-adrenergic receptor-Venus fusion protein domains on the surface of mammalian cells. Biochemical and Biophysical Research Communications. 382: 85-90. PMID 19265675 DOI: 10.1016/J.Bbrc.2009.02.144 |
0.744 |
|
| 2009 |
Pezacki JP, Sagan SM, Tonary AM, Rouleau Y, Bélanger S, Supekova L, Su AI. Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus. Bmc Chemical Biology. 9: 2. PMID 19149867 DOI: 10.1186/1472-6769-9-2 |
0.802 |
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| 2009 |
McKay CS, Kennedy DC, Pezacki JP. Studies of multicomponent Kinugasa reactions in aqueous media Tetrahedron Letters. 50: 1893-1896. DOI: 10.1016/J.Tetlet.2009.02.035 |
0.707 |
|
| 2009 |
Koukiekolo R, Jakubek ZJ, Cheng J, Sagan SM, Pezacki JP. Erratum to “Studies of a viral suppressor of RNA silencing p19-CFP fusion protein: A FRET-based probe for sensing double-stranded fluorophore tagged small RNAs” [Biophysical Chemistry 143 (2009) 166–169] Biophysical Chemistry. 145: 45. DOI: 10.1016/J.Bpc.2009.08.005 |
0.677 |
|
| 2008 |
Davis M, Sagan SM, Pezacki JP, Evans DJ, Simmonds P. Bioinformatic and physical characterizations of genome-scale ordered RNA structure in mammalian RNA viruses. Journal of Virology. 82: 11824-36. PMID 18799591 DOI: 10.1128/Jvi.01078-08 |
0.678 |
|
| 2008 |
Cheng J, Sagan SM, Jakubek ZJ, Pezacki JP. Studies of the interaction of the viral suppressor of RNA silencing protein p19 with small RNAs using fluorescence polarization. Biochemistry. 47: 8130-8. PMID 18597480 DOI: 10.1021/Bi800401Y |
0.67 |
|
| 2008 |
Lorello GR, Legault MC, Raki? B, Bisgaard K, Pezacki JP. Synthesis and bioorthogonal coupling chemistry of a novel cyclopentenone-containing unnatural tyrosine analogue. Bioorganic Chemistry. 36: 105-11. PMID 18272199 DOI: 10.1016/J.Bioorg.2007.12.006 |
0.306 |
|
| 2008 |
Supekova L, Supek F, Lee J, Chen S, Gray N, Pezacki JP, Schlapbach A, Schultz PG. Identification of human kinases involved in hepatitis C virus replication by small interference RNA library screening. The Journal of Biological Chemistry. 283: 29-36. PMID 17951261 DOI: 10.1074/Jbc.M703988200 |
0.534 |
|
| 2007 |
Cheng J, Sagan SM, Assem N, Koukiekolo R, Goto NK, Pezacki JP. Stabilized recombinant suppressors of RNA silencing: functional effects of linking monomers of Carnation Italian Ringspot virus p19. Biochimica Et Biophysica Acta. 1774: 1528-35. PMID 17976393 DOI: 10.1016/J.Bbapap.2007.09.014 |
0.665 |
|
| 2007 |
Noestheden M, Hu Q, Tonary AM, Tay LL, Pezacki JP. Evaluation of chemical labeling strategies for monitoring HCV RNA using vibrational microscopy. Organic & Biomolecular Chemistry. 5: 2380-9. PMID 17637957 DOI: 10.1039/B704812B |
0.347 |
|
| 2007 |
Koukiekolo R, Sagan SM, Pezacki JP. Effects of pH and salt concentration on the siRNA binding activity of the RNA silencing suppressor protein p19. Febs Letters. 581: 3051-6. PMID 17559839 DOI: 10.1016/J.Febslet.2007.05.064 |
0.668 |
|
| 2007 |
Sagan SM, Koukiekolo R, Rodgers E, Goto NK, Pezacki JP. Inhibition of siRNA binding to a p19 viral suppressor of RNA silencing by cysteine alkylation. Angewandte Chemie (International Ed. in English). 46: 2005-9. PMID 17286327 DOI: 10.1002/Anie.200603284 |
0.663 |
|
| 2006 |
Nan X, Tonary AM, Stolow A, Xie XS, Pezacki JP. Intracellular imaging of HCV RNA and cellular lipids by using simultaneous two-photon fluorescence and coherent anti-Stokes Raman scattering microscopies. Chembiochem : a European Journal of Chemical Biology. 7: 1895-7. PMID 17068839 DOI: 10.1002/Cbic.200600330 |
0.387 |
|
| 2006 |
Rakic B, Clarke J, Tremblay TL, Taylor J, Schreiber K, Nelson KM, Abrams SR, Pezacki JP. A small-molecule probe for hepatitis C virus replication that blocks protein folding. Chemistry & Biology. 13: 1051-60. PMID 17052609 DOI: 10.1016/J.Chembiol.2006.08.010 |
0.778 |
|
| 2006 |
Raki? B, Brûlotte M, Rouleau Y, Bélanger S, Pezacki JP. Bleomycin is a potent small-molecule inhibitor of hepatitis C virus replication. Chembiochem : a European Journal of Chemical Biology. 7: 1330-3. PMID 16888741 DOI: 10.1002/Cbic.200600180 |
0.775 |
|
| 2006 |
Tonary AM, Pezacki JP. Simultaneous quantitative measurement of luciferase reporter activity and cell number in two- and three-dimensional cultures of hepatitis C virus replicons. Analytical Biochemistry. 350: 239-48. PMID 16480942 DOI: 10.1016/J.Ab.2006.01.015 |
0.341 |
|
| 2006 |
Sagan SM, Rouleau Y, Leggiadro C, Supekova L, Schultz PG, Su AI, Pezacki JP. The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 67-79. PMID 16462891 DOI: 10.1139/O05-149 |
0.801 |
|
| 2006 |
Rakic B, Sagan SM, Noestheden M, Bélanger S, Nan X, Evans CL, Xie XS, Pezacki JP. Peroxisome proliferator-activated receptor alpha antagonism inhibits hepatitis C virus replication. Chemistry & Biology. 13: 23-30. PMID 16426968 DOI: 10.1016/J.Chembiol.2005.10.006 |
0.805 |
|
| 2005 |
Ianoul A, Grant DD, Rouleau Y, Bani-Yaghoub M, Johnston LJ, Pezacki JP. Imaging nanometer domains of beta-adrenergic receptor complexes on the surface of cardiac myocytes. Nature Chemical Biology. 1: 196-202. PMID 16408035 DOI: 10.1038/Nchembio726 |
0.743 |
|
| 2002 |
Su AI, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Bukh J, Purcell RH, Schultz PG, Chisari FV. Genomic analysis of the host response to hepatitis C virus infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 15669-74. PMID 12441396 DOI: 10.1073/Pnas.202608199 |
0.422 |
|
| 2002 |
Su AI, Guidotti LG, Pezacki JP, Chisari FV, Schultz PG. Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 11181-6. PMID 12177410 DOI: 10.1073/Pnas.122359899 |
0.405 |
|
| 2002 |
Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer DE. Genomic effects of polyamide/DNA interactions on mRNA expression. Chemistry & Biology. 9: 821-7. PMID 12144926 DOI: 10.1016/S1074-5521(02)00174-6 |
0.445 |
|
| 2000 |
Pezacki JP, Loncke PG, Ross JP, Warkentin J, Gadosy TA. Silicon migration from oxygen to carbon and decarbonylation in methoxytriphenylsiloxycarbene. Organic Letters. 2: 2733-6. PMID 10964352 DOI: 10.1021/Ol006117+ |
0.471 |
|
| 1999 |
Tae EL, Zhu Z, Platz MS, Pezacki JP, Warkentin J. Chemistry and Kinetics of Dipropylcarbene in Solution Journal of Physical Chemistry A. 103: 5336-5342. DOI: 10.1021/Jp990198D |
0.462 |
|
| 1999 |
Pezacki JP, Couture P, Dunn JA, Warkentin J, Wood PD, Lusztyk J, Ford F, Platz MS. Rate constants for 1,2-hydrogen migration in cyclohexylidene and in substituted cyclohexylidenes Journal of Organic Chemistry. 64: 4456-4464. DOI: 10.1021/Jo990171Q |
0.465 |
|
| 1999 |
Dunn JA, Pezacki JP, McGlinchey MJ, Warkentin J. Reactions of dimethoxycarbene with cyclic perchlorinated olefins and ketones Journal of Organic Chemistry. 64: 4344-4352. DOI: 10.1021/Jo9823846 |
0.503 |
|
| 1999 |
Pezacki JP, Shukla D, Lusztyk J, Warkentin J. Lifetimes of dialkylcarbocations derived from alkanediazonium ions in solution: Cyclohexadienyl cations as kinetic probes for cation reactivity Journal of the American Chemical Society. 121: 6589-6598. DOI: 10.1021/Ja9840807 |
0.488 |
|
| 1998 |
Muchall HM, Werstiuk NH, Choudhury B, Ma J, Warkentin J, Pezacki JP. Thermolysis of 2,2-dimethoxy-5,5-dimethyl-Δ3-1,3,4-oxadiagoline studied with photoelectron spectroscopy. He(I) photoelectron spectrum of dimethoxycarbene Canadian Journal of Chemistry. 76: 238-240. DOI: 10.1139/V97-233 |
0.445 |
|
| 1998 |
Pezacki JP, Wood PD, Gadosy TA, Lusztyk J, Warkentin J. Laser flash photolysis studies of oxygen and sulfur atom transfer reactions from oxiranes and thiiranes to singlet carbenes Journal of the American Chemical Society. 120: 8681-8691. DOI: 10.1021/Ja973469B |
0.476 |
|
| 1998 |
Pezacki JP, Warkentin J, Wood PD, Lusztyk J, Yuzawa T, Gudmundsdóttir AD, Morgan S, Platz MS. Laser flash photolysis of 2-adamantane-2,31-[3H]-diazirine: A reinvestigation Journal of Photochemistry and Photobiology a: Chemistry. 116: 1-7. DOI: 10.1016/S1010-6030(98)00287-1 |
0.459 |
|
| 1997 |
Pezacki JP, Wagner BD, Lew CSQ, Warkentin J, Lusztyk J. Δ3-1,3,4-oxadiazolines: Photochemical precursors to diazoalkanes and sec-alkanediazonium ions in acidic solution Journal of the American Chemical Society. 119: 1789-1790. DOI: 10.1021/Ja962550W |
0.448 |
|
| 1997 |
Pezacki JP, Pole DL, Warkentin J, Chen T, Ford F, Toscano JP, Fell J, Platz MS. Laser flash and dual wavelength photolysis of 3,4-diaza-2,2-dimethoxy-1-oxa[4.5]spirooct-3-ene. Migration of hydrogen and carbon in cyclobutylidene and in the excited state of its precursor Journal of the American Chemical Society. 119: 3191-3192. DOI: 10.1021/Ja961933R |
0.451 |
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