Gregory T. Motz, Ph.D.

Affiliations: 
2010 Toxicology (Environmental Health) University of Cincinnati, Cincinnati, OH 
Area:
Immunology, Medicine and Surgery, Public Health, Environmental Health
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"Gregory Motz"

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Michael Borchers grad student 2010 University of Cincinnati
 (The role of cigarette smoke exposure-induced activation of the innate and adaptive pulmonary immune system in the pathogenesis of chronic obstructive pulmonary disease.)
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Publications

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Santoro SP, Kim S, Motz GT, et al. (2015) T cells bearing a chimeric antigen receptor against prostate-specific membrane antigen mediate vascular disruption and result in tumor regression. Cancer Immunology Research. 3: 68-84
Melero I, Rouzaut A, Motz GT, et al. (2014) T-Cell and NK-Cell Infiltration into Solid Tumors: A Key Limiting Factor for Efficacious Cancer Immunotherapy Cancer Discovery. 4: 522-526
Motz GT, Santoro SP, Wang LP, et al. (2014) Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors. Nature Medicine. 20: 607-15
Motz GT, Coukos G. (2013) Deciphering and reversing tumor immune suppression. Immunity. 39: 61-73
Chiang CL, Kandalaft LE, Tanyi J, et al. (2013) A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4801-15
Facciabene A, Motz GT, Coukos G. (2012) T-regulatory cells: key players in tumor immune escape and angiogenesis. Cancer Research. 72: 2162-71
Wortham BW, Eppert BL, Motz GT, et al. (2012) NKG2D mediates NK cell hyperresponsiveness and influenza-induced pathologies in a mouse model of chronic obstructive pulmonary disease. Journal of Immunology (Baltimore, Md. : 1950). 188: 4468-75
Motz GT, Coukos G. (2011) The parallel lives of angiogenesis and immunosuppression: cancer and other tales. Nature Reviews. Immunology. 11: 702-11
Kandalaft LE, Motz GT, Duraiswamy J, et al. (2011) Tumor immune surveillance and ovarian cancer: lessons on immune mediated tumor rejection or tolerance. Cancer Metastasis Reviews. 30: 141-51
Kandalaft LE, Motz GT, Busch J, et al. (2011) Angiogenesis and the tumor vasculature as antitumor immune modulators: the role of vascular endothelial growth factor and endothelin. Current Topics in Microbiology and Immunology. 344: 129-48
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