Daniel Afosah
Affiliations: | 2012-2021 | Virginia Commonwealth University, Richmond, VA, United States | |
2021- | Washington and Lee University, Lexington, VA, United States |
Area:
Synthetic organic chemistry, computer-aided drug design, and biochemical techniquesWebsite:
https://my.wlu.edu/directory/profile?ID=x28004Google:
"Daniel Afosah"Mean distance: (not calculated yet)
Parents
Sign in to add mentorUmesh R. Desai | grad student | 2012-2017 | VCU | |
(PhD: Study of Interactions of Glycosaminoglycans (GAGs) and GAG Mimetics with their Protein Targets. Also post-doc from 2017-2021) |
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Publications
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Al-Horani RA, Abdelfadiel EI, Afosah DK, et al. (2019) A Synthetic Heparin Mimetic That Allosterically Inhibits Factor XIa and Reduces Thrombosis In Vivo Without Enhanced Risk of Bleeding. Journal of Thrombosis and Haemostasis : Jth |
Morla S, Sankaranarayanan NV, Afosah DK, et al. (2019) On the Process of Discovering Leads that Target the Heparin-Binding Site of Neutrophil Elastase in the Sputum of Cystic Fibrosis Patients. Journal of Medicinal Chemistry |
Patel NR, Patel DV, Kanhed AM, et al. (2019) 2-Aminobenzamide-Based Factor Xa Inhibitors with Novel Mono- and Bi-Aryls as S4 Binding Elements Chemistryselect. 4: 802-809 |
Afosah DK, Al-Horani RA. (2018) Sulfated Non-Saccharide Glycosaminoglycan Mimetics as Novel Drug Discovery Platform for Various Pathologies. Current Medicinal Chemistry |
Gangji RN, Sankaranarayanan NV, Elste J, et al. (2018) Inhibition of Herpes Simplex Virus-1 Entry into Human Cells by Nonsaccharide Glycosaminoglycan Mimetics. Acs Medicinal Chemistry Letters. 9: 797-802 |
Kummarapurugu AB, Afosah DK, Sankaranarayanan NV, et al. (2018) Molecular principles for heparin oligosaccharide-based inhibition of neutrophil elastase in cystic fibrosis. The Journal of Biological Chemistry |
Al-Horani RA, Afosah DK. (2018) Recent advances in the discovery and development of factor XI/XIa inhibitors. Medicinal Research Reviews. 38: 1974-2023 |
Afosah DK, Verespy S, Al-Horani RA, et al. (2018) A small group of sulfated benzofurans induces steady-state submaximal inhibition of thrombin. Bioorganic & Medicinal Chemistry Letters |
Afosah DK, Al-Horani RA, Sankaranarayanan NV, et al. (2016) Potent, Selective, Allosteric Inhibition of Human Plasmin by Sulfated Non-Saccharide Glycosaminoglycan Mimetics. Journal of Medicinal Chemistry |
Zheng S, Kummarapurugu AB, Afosah DK, et al. (2016) 2-O, 3-O Desulfated Heparin Blocks HMGB1 Release by Inhibition of p300 Acetyltransferase Activity. American Journal of Respiratory Cell and Molecular Biology |