| Year |
Citation |
Score |
| 2020 |
Pavel MA, Petersen EN, Wang H, Lerner RA, Hansen SB. Studies on the mechanism of general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. PMID 32467161 DOI: 10.1073/Pnas.2004259117 |
0.362 |
|
| 2019 |
Petersen EN, Pavel MA, Wang H, Hansen SB. Disruption of palmitate-mediated localization; a shared pathway of force and anesthetic activation of TREK-1 channels. Biochimica Et Biophysica Acta. Biomembranes. 183091. PMID 31672538 DOI: 10.1016/J.Bbamem.2019.183091 |
0.386 |
|
| 2019 |
Robinson CV, Rohacs T, Hansen SB. Tools for Understanding Nanoscale Lipid Regulation of Ion Channels. Trends in Biochemical Sciences. PMID 31060927 DOI: 10.1016/J.Tibs.2019.04.001 |
0.354 |
|
| 2018 |
Chung HW, Nicholas Petersen E, Cabanos C, Murphy KR, Pavel MA, Hansen AS, Ja WW, Hansen SB. A Molecular Target for an Alcohol Chain Length Cutoff. Journal of Molecular Biology. PMID 30529033 DOI: 10.1016/J.Jmb.2018.11.028 |
0.721 |
|
| 2017 |
Cabanos C, Wang M, Han X, Hansen SB. A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Reports. 20: 1287-1294. PMID 28793254 DOI: 10.1016/J.Celrep.2017.07.034 |
0.742 |
|
| 2015 |
Hansen SB. Lipid agonism: The PIP2 paradigm of ligand-gated ion channels. Biochimica Et Biophysica Acta. 1851: 620-628. PMID 25633344 DOI: 10.1016/J.Bbalip.2015.01.011 |
0.401 |
|
| 2011 |
Hansen SB, Tao X, MacKinnon R. Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2. Nature. 477: 495-8. PMID 21874019 DOI: 10.1038/Nature10370 |
0.486 |
|
| 2010 |
Sine SM, Wang HL, Hansen S, Taylor P. On the origin of ion selectivity in the Cys-loop receptor family. Journal of Molecular Neuroscience : Mn. 40: 70-6. PMID 19728176 DOI: 10.1007/S12031-009-9260-1 |
0.71 |
|
| 2008 |
Hansen SB, Wang HL, Taylor P, Sine SM. An ion selectivity filter in the extracellular domain of Cys-loop receptors reveals determinants for ion conductance. The Journal of Biological Chemistry. 283: 36066-70. PMID 18940802 DOI: 10.1074/Jbc.C800194200 |
0.703 |
|
| 2007 |
Taylor P, Talley TT, Radic' Z, Hansen SB, Hibbs RE, Shi J. Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes. Biochemical Pharmacology. 74: 1164-71. PMID 17826748 DOI: 10.1016/J.Bcp.2007.07.038 |
0.794 |
|
| 2007 |
Hansen SB, Taylor P. Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. Journal of Molecular Biology. 369: 895-901. PMID 17481657 DOI: 10.1016/J.Jmb.2007.03.067 |
0.691 |
|
| 2006 |
Bourne Y, Hansen SB, Sulzenbacher G, Talley TT, Huxford T, Taylor P, Marchot P. Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein. Journal of Molecular Neuroscience : Mn. 30: 103-4. PMID 17192648 DOI: 10.1385/Jmn:30:1:103 |
0.746 |
|
| 2006 |
Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Bourne Y, Taylor P. Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica. Journal of Molecular Neuroscience : Mn. 30: 101-2. PMID 17192647 DOI: 10.1385/Jmn:30:1:101 |
0.696 |
|
| 2006 |
Gao F, Mer G, Tonelli M, Hansen SB, Burghardt TP, Taylor P, Sine SM. Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop. Molecular Pharmacology. 70: 1230-5. PMID 16847142 DOI: 10.1124/Mol.106.027185 |
0.712 |
|
| 2006 |
Radić Z, Talley TT, Hansen SB, Yu W, Taylor P. Interaction of organophosphate and carbamate cholinesterase inhibitors with acetylcholine binding proteins Toxicology Letters. 164: S239. DOI: 10.1016/J.Toxlet.2006.07.157 |
0.742 |
|
| 2005 |
Hibbs RE, Johnson DA, Shi J, Hansen SB, Taylor P. Structural dynamics of the alpha-neurotoxin-acetylcholine-binding protein complex: hydrodynamic and fluorescence anisotropy decay analyses. Biochemistry. 44: 16602-11. PMID 16342951 DOI: 10.1021/Bi051735P |
0.74 |
|
| 2005 |
Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Taylor P, Bourne Y. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. The Embo Journal. 24: 3635-46. PMID 16193063 DOI: 10.1038/Sj.Emboj.7600828 |
0.711 |
|
| 2005 |
Bourne Y, Talley TT, Hansen SB, Taylor P, Marchot P. Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors. The Embo Journal. 24: 1512-22. PMID 15791209 DOI: 10.1038/Sj.Emboj.7600620 |
0.787 |
|
| 2005 |
Gao F, Bren N, Burghardt TP, Hansen S, Henchman RH, Taylor P, McCammon JA, Sine SM. Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence. The Journal of Biological Chemistry. 280: 8443-51. PMID 15591050 DOI: 10.1074/Jbc.M412389200 |
0.739 |
|
| 2004 |
Bouzat C, Gumilar F, Spitzmaul G, Wang HL, Rayes D, Hansen SB, Taylor P, Sine SM. Coupling of agonist binding to channel gating in an ACh-binding protein linked to an ion channel. Nature. 430: 896-900. PMID 15318223 DOI: 10.1038/Nature02753 |
0.753 |
|
| 2004 |
Hansen SB, Talley TT, Radic Z, Taylor P. Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica. The Journal of Biological Chemistry. 279: 24197-202. PMID 15069068 DOI: 10.1074/Jbc.M402452200 |
0.781 |
|
| 2004 |
Taylor P, Hansen SB, Talley TT, Hibbs RE, Radi? Z. Contemporary paradigms for cholinergic ligand design guided by biological structure. Bioorganic & Medicinal Chemistry Letters. 14: 1875-7. PMID 15050619 DOI: 10.1016/J.Bmcl.2003.10.072 |
0.772 |
|
| 2003 |
Gao F, Bern N, Little A, Wang HL, Hansen SB, Talley TT, Taylor P, Sine SM. Curariform antagonists bind in different orientations to acetylcholine-binding protein. The Journal of Biological Chemistry. 278: 23020-6. PMID 12682067 DOI: 10.1074/Jbc.M301151200 |
0.801 |
|
| 2002 |
Hansen SB, Radic' Z, Talley TT, Molles BE, Deerinck T, Tsigelny I, Taylor P. Tryptophan fluorescence reveals conformational changes in the acetylcholine binding protein. The Journal of Biological Chemistry. 277: 41299-302. PMID 12235129 DOI: 10.1074/Jbc.C200462200 |
0.802 |
|
| 2000 |
Ishizu K, Smith DF, Bender D, Danielsen E, Hansen SB, Wong DF, Cumming P, Gjedde A. Positron emission tomography of radioligand binding in porcine striatum in vivo: haloperidol inhibition linked to endogenous ligand release. Synapse (New York, N.Y.). 38: 87-101. PMID 10941144 DOI: 10.1002/1098-2396(200010)38:1<87::Aid-Syn10>3.0.Co;2-C |
0.343 |
|
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