| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2023 | Finlay DB, Mackie W, Webb HDJ, Thomsen LR, Nimick M, Rosengren RJ, Marusich JA, Glass M, Wiley JL. The piperazine analogue para-fluorophenylpiperazine alters timing of the physiological effects of the synthetic cannabinoid receptor agonist AMB-FUBINACA, without changing its discriminative stimulus, signalling effects, or metabolism. Pharmacology, Biochemistry, and Behavior. 223: 173530. PMID 36805861 DOI: 10.1016/j.pbb.2023.173530 | 0.411 | |||
| 2022 | Marusich JA, Gamage TF, Zhang Y, Akinfiresoye LR, Wiley JL. In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists. Pharmacology, Biochemistry, and Behavior. 220: 173467. PMID 36154844 DOI: 10.1016/j.pbb.2022.173467 | 0.776 | |||
| 2022 | Finlay DB, Nguyen T, Gamage TF, Chen S, Barrus DG, Patel PR, Thomas BF, Wiley JL, Zhang Y, Glass M. Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG-018. Pharmacology Research & Perspectives. 10: e00901. PMID 35041297 DOI: 10.1002/prp2.901 | 0.809 | |||
| 2020 | Wiley JL, Barrus DG, Farquhar CE, Lefever TW, Gamage TF. Sex, species and age: Effects of rodent demographics on the pharmacology of ∆-tetrahydrocanabinol. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110064. PMID 32810571 DOI: 10.1016/J.Pnpbp.2020.110064 | 0.771 | |||
| 2020 | Gamage TF, Barrus DG, Kevin RC, Finlay DB, Lefever TW, Patel PR, Grabenauer MA, Glass M, McGregor IS, Wiley JL, Thomas BF. In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018. Pharmacology, Biochemistry, and Behavior. 172918. PMID 32247816 DOI: 10.1016/J.Pbb.2020.172918 | 0.836 | |||
| 2019 | Lefever TW, Thomas BF, Kovach AL, Snyder RW, Wiley JL. Route of administration effects on nicotine discrimination in female and male mice. Drug and Alcohol Dependence. 204: 107504. PMID 31476643 DOI: 10.1016/J.Drugalcdep.2019.06.007 | 0.593 | |||
| 2019 | Marusich JA, Wiley JL, Silinski MAR, Thomas BF, Meredith SE, Gahl RF, Jackson KJ. Comparison of Cigarette, Little Cigar, and Waterpipe Tobacco Smoke Condensate and E-Cigarette Aerosol Condensate in a Self-administration Model. Behavioural Brain Research. 112061. PMID 31254537 DOI: 10.1016/J.Bbr.2019.112061 | 0.555 | |||
| 2019 | Wiley JL, Lefever TW, Michelle Glass MA, Thomas BF. Do You Feel It Now? Route of Administration and Δ-Tetrahydrocannabinol-Like Discriminative Stimulus Effects of Synthetic Cannabinoids in Mice. Neurotoxicology. PMID 30953678 DOI: 10.1016/J.Neuro.2019.04.002 | 0.647 | |||
| 2019 | Kevin RC, Kovach AL, Lefever TW, Gamage TF, Wiley JL, McGregor IS, Thomas BF. Toxic by design? Formation of thermal degradants and cyanide from carboxamide-type synthetic cannabinoids CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18 during exposure to high temperatures. Forensic Toxicology. 37: 17-26. PMID 30705707 DOI: 10.1007/S11419-018-0430-0 | 0.752 | |||
| 2018 | Gamage TF, Farquhar CE, McKinnie RJ, Kevin RC, McGregor IS, Trudell M, Wiley JL, Thomas BF. Synthetic cannabinoid hydroxypentyl metabolites retain efficacy at human cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 30552295 DOI: 10.1124/Jpet.118.254425 | 0.812 | |||
| 2018 | Farquhar CE, Breivogel CS, Gamage TF, Gay EA, Thomas BF, Craft RM, Wiley JL. Sex, THC, and hormones: Effects on density and sensitivity of CB cannabinoid receptors in rats. Drug and Alcohol Dependence. 194: 20-27. PMID 30391834 DOI: 10.1016/J.Drugalcdep.2018.09.018 | 0.787 | |||
| 2018 | Greene NZ, Wiley JL, Yu Z, Clowers BH, Craft RM. Cannabidiol modulation of antinociceptive tolerance to Δ-tetrahydrocannabinol. Psychopharmacology. PMID 30238130 DOI: 10.1007/S00213-018-5036-Z | 0.308 | |||
| 2018 | Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation. Acs Chemical Neuroscience. PMID 30188693 DOI: 10.1021/Acschemneuro.8B00396 | 0.802 | |||
| 2018 | Barrus DG, Lefever TW, Wiley JL. Evaluation of reinforcing and aversive effects of voluntary Δ-tetrahydrocannabinol ingestion in rats. Neuropharmacology. 137: 133-140. PMID 29758385 DOI: 10.1016/J.Neuropharm.2018.04.018 | 0.363 | |||
| 2018 | Gamage TF, Farquhar CE, Lefever TW, Marusich JA, Kevin RC, McGregor IS, Wiley JL, Thomas BF. Molecular and behavioral pharmacological characterization of abused synthetic cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-fluoro-CUMYL-PICA. The Journal of Pharmacology and Experimental Therapeutics. PMID 29549157 DOI: 10.1124/Jpet.117.246983 | 0.826 | |||
| 2017 | Marusich JA, Wiley JL, Lefever TW, Patel PR, Thomas BF. Finding order in chemical chaos - Continuing characterization of synthetic cannabinoid receptor agonists. Neuropharmacology. PMID 29113898 DOI: 10.1016/J.Neuropharm.2017.10.041 | 0.666 | |||
| 2017 | Marusich JA, Darna M, Wilson AG, Denehy ED, Ebben A, Deaciuc AG, Dwoskin LP, Bardo MT, Lefever TW, Wiley JL, Reissig CJ, Jackson KJ. Tobacco's minor alkaloids: effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats. European Journal of Pharmacology. PMID 28844873 DOI: 10.1016/J.Ejphar.2017.08.029 | 0.319 | |||
| 2017 | Kevin RC, Lefever TW, Snyder RW, Patel PR, Gamage TF, Fennell TR, Wiley JL, McGregor IS, Thomas BF. Kinetic and metabolic profiles of synthetic cannabinoids NNEI and MN-18. Drug Testing and Analysis. PMID 28834241 DOI: 10.1002/Dta.2262 | 0.775 | |||
| 2017 | Kevin RC, Lefever TW, Snyder RW, Patel PR, Fennell TR, Wiley JL, McGregor IS, Thomas BF. In vitro and in vivo pharmacokinetics and metabolism of synthetic cannabinoids CUMYL-PICA and 5F-CUMYL-PICA. Forensic Toxicology. 35: 333-347. PMID 28824730 DOI: 10.1007/S11419-017-0361-1 | 0.579 | |||
| 2017 | Gamage TF, Farquhar CE, Lefever TW, Thomas BF, Nguyen T, Zhang Y, Wiley JL. The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulators. Neuropharmacology. PMID 28803965 DOI: 10.1016/J.Neuropharm.2017.08.008 | 0.825 | |||
| 2017 | Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution. Journal of Medicinal Chemistry. PMID 28792219 DOI: 10.1021/Acs.Jmedchem.7B00707 | 0.816 | |||
| 2017 | Owens RA, Mustafa MA, Ignatowska-Jankowska BM, Damaj MI, Beardsley PM, Wiley JL, Niphakis MJ, Cravatt BF, Lichtman AH. Inhibition of the endocannabinoid-regulating enzyme monoacylglycerol lipase elicits a CB1 receptor-mediated discriminative stimulus in mice. Neuropharmacology. PMID 28673548 DOI: 10.1016/J.Neuropharm.2017.06.032 | 0.644 | |||
| 2017 | Lefever TW, Marusich JA, Thomas BF, Barrus DG, Peiper NC, Kevin RC, Wiley JL. Vaping Synthetic Cannabinoids: A Novel Preclinical Model of E-Cigarette Use in Mice. Substance Abuse : Research and Treatment. 11: 1178221817701739. PMID 28469427 DOI: 10.1177/1178221817701739 | 0.623 | |||
| 2017 | Britch SC, Wiley JL, Yu Z, Clowers BH, Craft RM. Cannabidiol-Δ(9)-tetrahydrocannabinol interactions on acute pain and locomotor activity. Drug and Alcohol Dependence. 175: 187-197. PMID 28445853 DOI: 10.1016/J.Drugalcdep.2017.01.046 | 0.33 | |||
| 2017 | Grim TW, Morales AJ, Thomas BF, Wiley JL, Endres GW, Negus SS, Lichtman AH. Apparent CB1 receptor rimonabant affinity estimates: combination with THC and synthetic cannabinoids in the mouse in vivo triad model. The Journal of Pharmacology and Experimental Therapeutics. PMID 28442584 DOI: 10.1124/Jpet.117.240192 | 0.746 | |||
| 2017 | Lefever TW, Lee YO, Kovach AL, Silinski MA, Marusich JA, Thomas BF, Wiley JL. Delivery of nicotine aerosol to mice via a modified electronic cigarette device. Drug and Alcohol Dependence. 172: 80-87. PMID 28157590 DOI: 10.1016/J.Drugalcdep.2016.12.004 | 0.565 | |||
| 2017 | Wiley JL, Lefever TW, Marusich JA, Craft RM. Comparison of the discriminative stimulus and response rate effects of (Δ9)-tetrahydrocannabinol and synthetic cannabinoids in female and male rats. Drug and Alcohol Dependence. 172: 51-59. PMID 28130989 DOI: 10.1016/J.Drugalcdep.2016.11.035 | 0.341 | |||
| 2017 | Thomas BF, Lefever TW, Cortes RA, Kovach AL, Cox AO, Patel PR, Pollard GT, Marusich JA, Kevin RA, Gamage TF, Wiley JL. Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. The Journal of Pharmacology and Experimental Therapeutics. PMID 28087785 DOI: 10.1124/Jpet.116.238717 | 0.805 | |||
| 2017 | Maitra R, Manke A, Wiethe R, Amato G, Snyder R, Vasukuttan V, Cortes R, Lefever T, Wiley J, Harris D, Runyon R. OR4-5DEVELOPMENT OF a peripherally restricted CB1 receptor antagonist FOR ALCOHOLIC STEATOSIS Alcohol and Alcoholism. 52. DOI: 10.1093/Alcalc/Agx074.42 | 0.349 | |||
| 2017 | Marusich JA, Lefever T, Blough B, Thomas B, Wiley J. Pharmacological effects of injected or vaporized methamphetamine and alpha-PVP in mice Drug and Alcohol Dependence. 171: e130. DOI: 10.1016/J.Drugalcdep.2016.08.361 | 0.563 | |||
| 2016 | Nguyen T, Li JX, Thomas BF, Wiley JL, Kenakin TP, Zhang Y. Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor. Medicinal Research Reviews. PMID 27879006 DOI: 10.1002/Med.21418 | 0.657 | |||
| 2016 | Wiley JL, Marusich JA, Thomas BF. Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids. Current Topics in Behavioral Neurosciences. PMID 27753007 DOI: 10.1007/7854_2016_17 | 0.661 | |||
| 2016 | Craft RM, Haas AE, Wiley JL, Yu Z, Clowers BH. Gonadal hormone modulation of ∆(9)-tetrahydrocannabinol-induced antinociception and metabolism in female versus male rats. Pharmacology, Biochemistry, and Behavior. PMID 27670094 DOI: 10.1016/J.Pbb.2016.09.006 | 0.316 | |||
| 2016 | Grim TW, Morales AJ, Gonek MM, Wiley JL, Thomas BF, Endres GW, Sim-Selley LJ, Selley DE, Negus SS, Lichtman AH. Stratification of cannabinoid 1 receptor (CB1R) agonist efficacy: Manipulation of CB1R density through use of transgenic mice reveals congruence between in vivo and in vitro assays. The Journal of Pharmacology and Experimental Therapeutics. PMID 27535976 DOI: 10.1124/Jpet.116.233163 | 0.744 | |||
| 2016 | Wiley JL, Lefever TW, Marusich JA, Grabenauer M, Moore KN, Huffman JW, Thomas BF. Evaluation of first generation synthetic cannabinoids on binding at non-cannabinoid receptors and in a battery of in vivo assays in mice. Neuropharmacology. PMID 27449567 DOI: 10.1016/J.Neuropharm.2016.07.016 | 0.716 | |||
| 2016 | Wiley JL, Lefever TW, Pulley NS, Marusich JA, Cravatt BF, Lichtman AH. Just add water: cannabinoid discrimination in a water T-maze with FAAH(-/-) and FAAH(+/+) mice. Behavioural Pharmacology. 27: 479-484. PMID 27385208 DOI: 10.1097/Fbp.0000000000000228 | 0.574 | |||
| 2016 | Owens RA, Ignatowska-Jankowska BM, Mustafa M, Beardsley PM, Wiley JL, Jali A, Selley DE, Niphakis M, Cravatt BF, Lichtman AH. Discriminative Stimulus Properties of the Endocannabinoid Catabolic Enzyme Inhibitor SA-57 in Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 27307500 DOI: 10.1124/Jpet.115.229492 | 0.638 | |||
| 2016 | Wiley JL, Owens RA, Lichtman AH. Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids. Current Topics in Behavioral Neurosciences. PMID 27278640 DOI: 10.1007/7854_2016_24 | 0.594 | |||
| 2016 | Marusich JA, Lefever TW, Blough BE, Thomas BF, Wiley JL. Pharmacological Effects of Methamphetamine and Alpha-PVP Vapor and Injection. Neurotoxicology. PMID 27237056 DOI: 10.1016/J.Neuro.2016.05.015 | 0.615 | |||
| 2015 | Marusich JA, Craft RM, Lefever TW, Wiley JL. The impact of gonadal hormones on cannabinoid dependence. Experimental and Clinical Psychopharmacology. 23: 206-16. PMID 26237318 DOI: 10.1037/Pha0000027 | 0.331 | |||
| 2015 | Wiley JL, Marusich JA, Lefever TW, Antonazzo KR, Wallgren MT, Cortes RA, Patel PR, Grabenauer M, Moore KN, Thomas BF. AB-CHMINACA, AB-PINACA, and FUBIMINA: Affinity and Potency of Novel Synthetic Cannabinoids in Producing Δ9-Tetrahydrocannabinol-Like Effects in Mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 26105953 DOI: 10.1124/Jpet.115.225326 | 0.685 | |||
| 2015 | Ignatowska-Jankowska BM, Baillie GL, Kinsey S, Crowe M, Ghosh S, Allen Owens R, Imad Damaj M, Poklis J, Wiley JL, Zanda M, Zanato C, Greig IR, Lichtman AH, Ross RA. A Cannabinoid CB1 Receptor Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with no Psychoactive Effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26052038 DOI: 10.1038/Npp.2015.148 | 0.62 | |||
| 2015 | Wakley AA, Wiley JL, Craft RM. Gonadal hormones do not alter the development of antinociceptive tolerance to delta-9-tetrahydrocannabinol in adult rats. Pharmacology, Biochemistry, and Behavior. 133: 111-21. PMID 25863271 DOI: 10.1016/J.Pbb.2015.03.021 | 0.321 | |||
| 2015 | Nguyen T, German N, Decker AM, Li JX, Wiley JL, Thomas BF, Kenakin TP, Zhang Y. Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators. Bioorganic & Medicinal Chemistry. 23: 2195-203. PMID 25797163 DOI: 10.1016/J.Bmc.2015.02.058 | 0.625 | |||
| 2015 | Ignatowska-Jankowska B, Wilkerson JL, Mustafa M, Abdullah R, Niphakis M, Wiley JL, Cravatt BF, Lichtman AH. Selective monoacylglycerol lipase inhibitors: antinociceptive versus cannabimimetic effects in mice. The Journal of Pharmacology and Experimental Therapeutics. 353: 424-32. PMID 25762694 DOI: 10.1124/Jpet.114.222315 | 0.646 | |||
| 2015 | Walentiny DM, Vann RE, Wiley JL. Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice. Neuropharmacology. 93: 237-42. PMID 25698527 DOI: 10.1016/J.Neuropharm.2015.02.004 | 0.808 | |||
| 2015 | Wiebelhaus JM, Grim TW, Owens RA, Lazenka MF, Sim-Selley LJ, Abdullah RA, Niphakis MJ, Vann RE, Cravatt BF, Wiley JL, Negus SS, Lichtman AH. Δ9-tetrahydrocannabinol and endocannabinoid degradative enzyme inhibitors attenuate intracranial self-stimulation in mice. The Journal of Pharmacology and Experimental Therapeutics. 352: 195-207. PMID 25398241 DOI: 10.1124/Jpet.114.218677 | 0.618 | |||
| 2015 | Wiley JL, Marusich JA, Thomas BF, Jackson KJ. Determination of behaviorally effective tobacco constituent doses in rats. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 17: 368-71. PMID 25271188 DOI: 10.1093/Ntr/Ntu194 | 0.579 | |||
| 2015 | Marusich JA, Lefever T, Craft R, Wiley J. Evaluation of sex differences in cannabinoid withdrawal in rats Drug and Alcohol Dependence. 146: e195. DOI: 10.1016/J.Drugalcdep.2014.09.446 | 0.306 | |||
| 2014 | Baumann MH, Solis E, Watterson LR, Marusich JA, Fantegrossi WE, Wiley JL. Baths salts, spice, and related designer drugs: the science behind the headlines. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15150-8. PMID 25392483 DOI: 10.1523/Jneurosci.3223-14.2014 | 0.33 | |||
| 2014 | German N, Decker AM, Gilmour BP, Gay EA, Wiley JL, Thomas BF, Zhang Y. Diarylureas as allosteric modulators of the cannabinoid CB1 receptor: structure-activity relationship studies on 1-(4-chlorophenyl)-3-{3-[6-(pyrrolidin-1-yl)pyridin-2-yl]phenyl}urea (PSNCBAM-1). Journal of Medicinal Chemistry. 57: 7758-69. PMID 25162172 DOI: 10.1021/Jm501042U | 0.663 | |||
| 2014 | Wiley JL, Burston JJ. Sex differences in Δ(9)-tetrahydrocannabinol metabolism and in vivo pharmacology following acute and repeated dosing in adolescent rats. Neuroscience Letters. 576: 51-5. PMID 24909619 DOI: 10.1016/J.Neulet.2014.05.057 | 0.339 | |||
| 2014 | Wiley JL, Lefever TW, Cortes RA, Marusich JA. Cross-substitution of Δ9-tetrahydrocannabinol and JWH-018 in drug discrimination in rats. Pharmacology, Biochemistry, and Behavior. 124: 123-8. PMID 24887450 DOI: 10.1016/J.Pbb.2014.05.016 | 0.405 | |||
| 2014 | Wiley JL, Walentiny DM, Wright MJ, Beardsley PM, Burston JJ, Poklis JL, Lichtman AH, Vann RE. Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. European Journal of Pharmacology. 737: 97-105. PMID 24858366 DOI: 10.1016/J.Ejphar.2014.05.013 | 0.83 | |||
| 2014 | Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. Behavioural Pharmacology. 25: 182-5. PMID 24603340 DOI: 10.1097/Fbp.0000000000000027 | 0.832 | |||
| 2014 | Marusich JA, Antonazzo KR, Wiley JL, Blough BE, Partilla JS, Baumann MH. Pharmacology of novel synthetic stimulants structurally related to the "bath salts" constituent 3,4-methylenedioxypyrovalerone (MDPV). Neuropharmacology. 87: 206-13. PMID 24594476 DOI: 10.1016/J.Neuropharm.2014.02.016 | 0.345 | |||
| 2014 | Lefever TW, Marusich JA, Antonazzo KR, Wiley JL. Evaluation of WIN 55,212-2 self-administration in rats as a potential cannabinoid abuse liability model. Pharmacology, Biochemistry, and Behavior. 118: 30-5. PMID 24412835 DOI: 10.1016/J.Pbb.2014.01.002 | 0.379 | |||
| 2014 | Wiley JL, Marusich JA, Huffman JW. Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids. Life Sciences. 97: 55-63. PMID 24071522 DOI: 10.1016/J.Lfs.2013.09.011 | 0.491 | |||
| 2014 | Ignatowska-Jankowska BM, Ghosh S, Crowe MS, Kinsey SG, Niphakis MJ, Abdullah RA, Tao Q, O' Neal ST, Walentiny DM, Wiley JL, Cravatt BF, Lichtman AH. In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: antinociceptive activity without cannabimimetic side effects. British Journal of Pharmacology. 171: 1392-407. PMID 23848221 DOI: 10.1111/Bph.12298 | 0.827 | |||
| 2014 | Daw R, Grabenauer M, Pande PG, Cox A, Kovach A, Davis K, Wiley J, Stout P, Thomas B. Pyrolysis studies of synthetic cannabinoids in herbal products Drug and Alcohol Dependence. 140: e44. DOI: 10.1016/J.Drugalcdep.2014.02.142 | 0.513 | |||
| 2013 | Fulp A, Bortoff K, Zhang Y, Snyder R, Fennell T, Marusich JA, Wiley JL, Seltzman H, Maitra R. Peripherally selective diphenyl purine antagonist of the CB1 receptor. Journal of Medicinal Chemistry. 56: 8066-72. PMID 24041123 DOI: 10.1021/Jm401129N | 0.483 | |||
| 2013 | Wiley JL, Marusich JA, Lefever TW, Grabenauer M, Moore KN, Thomas BF. Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles. Neuropharmacology. 75: 145-54. PMID 23916483 DOI: 10.1016/J.Neuropharm.2013.07.022 | 0.691 | |||
| 2013 | Walentiny D, Vann R, Mahadevan A, Kottani R, Gujjar R, Wiley J. Novel 3-substituted rimonabant analogues lack Δ(9) -tetrahydrocannabinol-like abuse-related behavioural effects in mice. British Journal of Pharmacology. 169: 10-20. PMID 23297801 DOI: 10.1111/Bph.12099 | 0.793 | |||
| 2013 | Craft RM, Marusich JA, Wiley JL. Sex differences in cannabinoid pharmacology: a reflection of differences in the endocannabinoid system? Life Sciences. 92: 476-81. PMID 22728714 DOI: 10.1016/J.Lfs.2012.06.009 | 0.311 | |||
| 2012 | Wiley JL, Marusich JA, Zhang Y, Fulp A, Maitra R, Thomas BF, Mahadevan A. Structural analogs of pyrazole and sulfonamide cannabinoids: effects on acute food intake in mice. European Journal of Pharmacology. 695: 62-70. PMID 22975289 DOI: 10.1016/J.Ejphar.2012.08.019 | 0.669 | |||
| 2012 | Marusich JA, Grant KR, Blough BE, Wiley JL. Effects of synthetic cathinones contained in "bath salts" on motor behavior and a functional observational battery in mice. Neurotoxicology. 33: 1305-13. PMID 22922498 DOI: 10.1016/J.Neuro.2012.08.003 | 0.405 | |||
| 2012 | Grabenauer M, Krol WL, Wiley JL, Thomas BF. Analysis of synthetic cannabinoids using high-resolution mass spectrometry and mass defect filtering: implications for nontargeted screening of designer drugs. Analytical Chemistry. 84: 5574-81. PMID 22724537 DOI: 10.1021/Ac300509H | 0.517 | |||
| 2012 | Cox AO, Daw RC, Mason MD, Grabenauer M, Pande PG, Davis KH, Wiley JL, Stout PR, Thomas BF, Huffman JW. Use of SPME-HS-GC-MS for the analysis of herbal products containing synthetic cannabinoids. Journal of Analytical Toxicology. 36: 293-302. PMID 22582264 DOI: 10.1093/Jat/Bks025 | 0.577 | |||
| 2012 | Tobey KM, Walentiny DM, Wiley JL, Carroll FI, Damaj MI, Azar MR, Koob GF, George O, Harris LS, Vann RE. Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice. Psychopharmacology. 223: 159-68. PMID 22526534 DOI: 10.1007/S00213-012-2703-3 | 0.782 | |||
| 2012 | Schank JR, Goldstein AL, Rowe KE, King CE, Marusich JA, Wiley JL, Carroll FI, Thorsell A, Heilig M. The kappa opioid receptor antagonist JDTic attenuates alcohol seeking and withdrawal anxiety. Addiction Biology. 17: 634-47. PMID 22515275 DOI: 10.1111/J.1369-1600.2012.00455.X | 0.315 | |||
| 2012 | Marusich JA, Wiley JL. Rimonabant abolishes sensitivity to workload changes in a progressive ratio procedure. Pharmacology, Biochemistry, and Behavior. 101: 575-80. PMID 22425597 DOI: 10.1016/J.Pbb.2012.03.004 | 0.332 | |||
| 2012 | Wiley JL, Smith VJ, Chen J, Martin BR, Huffman JW. Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents. Bioorganic & Medicinal Chemistry. 20: 2067-81. PMID 22341572 DOI: 10.1016/J.Bmc.2012.01.038 | 0.585 | |||
| 2012 | Wiley JL, Marusich JA, Martin BR, Huffman JW. 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice. Drug and Alcohol Dependence. 123: 148-53. PMID 22127210 DOI: 10.1016/J.Drugalcdep.2011.11.001 | 0.61 | |||
| 2012 | Wiley JL, Selley DE, Wang P, Kottani R, Gadthula S, Mahadeven A. 3-Substituted pyrazole analogs of the cannabinoid type 1 (CBâ‚) receptor antagonist rimonabant: cannabinoid agonist-like effects in mice via non-CBâ‚, non-CBâ‚‚ mechanism. The Journal of Pharmacology and Experimental Therapeutics. 340: 433-44. PMID 22085649 DOI: 10.1124/Jpet.111.187815 | 0.525 | |||
| 2012 | Vann RE, Walentiny DM, Burston JJ, Tobey KM, Gamage TF, Wiley JL. Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride. Neuropharmacology. 62: 1019-27. PMID 22051632 DOI: 10.1016/J.Neuropharm.2011.10.011 | 0.812 | |||
| 2011 | Wiley JL, Marusich JA, Huffman JW, Balster RL, Thomas BF. Hijacking of Basic Research: The Case of Synthetic Cannabinoids. Methods Report (Rti Press). 2011. PMID 23397508 DOI: 10.3768/rtipress.2011.op.0007.1111 | 0.481 | |||
| 2011 | Wiley JL, Evans RL, Grainger DB, Nicholson KL. Locomotor activity changes in female adolescent and adult rats during repeated treatment with a cannabinoid or club drug. Pharmacological Reports : Pr. 63: 1085-92. PMID 22180350 DOI: 10.1016/S1734-1140(11)70627-2 | 0.348 | |||
| 2011 | Wiley JL, Matthew Walentiny D, Vann RE, Baskfield CY. Dissimilar cannabinoid substitution patterns in mice trained to discriminate Δ(9)-tetrahydrocannabinol or methanandamide from vehicle. Behavioural Pharmacology. 22: 480-8. PMID 21712709 DOI: 10.1097/Fbp.0B013E328348Eced | 0.795 | |||
| 2011 | Walentiny DM, Gamage TF, Warner JA, Nguyen TK, Grainger DB, Wiley JL, Vann RE. The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. European Journal of Pharmacology. 656: 63-7. PMID 21300050 DOI: 10.1016/J.Ejphar.2011.01.056 | 0.813 | |||
| 2011 | Wiley JL, Breivogel CS, Mahadevan A, Pertwee RG, Cascio MG, Bolognini D, Huffman JW, Walentiny DM, Vann RE, Razdan RK, Martin BR. Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist. European Journal of Pharmacology. 651: 96-105. PMID 21114999 DOI: 10.1016/J.Ejphar.2010.10.085 | 0.823 | |||
| 2010 | Huffman JW, Hepburn SA, Lyutenko N, Thompson AL, Wiley JL, Selley DE, Martin BR. 1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-Δ(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor. Bioorganic & Medicinal Chemistry. 18: 7809-15. PMID 20943404 DOI: 10.1016/J.Bmc.2010.09.061 | 0.507 | |||
| 2010 | Burston JJ, Wiley JL, Craig AA, Selley DE, Sim-Selley LJ. Regional enhancement of cannabinoid CB₁ receptor desensitization in female adolescent rats following repeated Delta-tetrahydrocannabinol exposure. British Journal of Pharmacology. 161: 103-12. PMID 20718743 DOI: 10.1111/J.1476-5381.2010.00870.X | 0.335 | |||
| 2010 | Huffman JW, Hepburn SA, Reggio PH, Hurst DP, Wiley JL, Martin BR. Synthesis and pharmacology of 1-methoxy analogs of CP-47,497. Bioorganic & Medicinal Chemistry. 18: 5475-82. PMID 20621488 DOI: 10.1016/J.Bmc.2010.06.054 | 0.532 | |||
| 2010 | Thors L, Burston JJ, Alter BJ, McKinney MK, Cravatt BF, Ross RA, Pertwee RG, Gereau RW, Wiley JL, Fowler CJ. Biochanin A, a naturally occurring inhibitor of fatty acid amide hydrolase. British Journal of Pharmacology. 160: 549-60. PMID 20590565 DOI: 10.1111/J.1476-5381.2010.00716.X | 0.514 | |||
| 2010 | Damaj MI, Grabus SD, Navarro HA, Vann RE, Warner JA, King LS, Wiley JL, Blough BE, Lukas RJ, Carroll FI. Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 1087-95. PMID 20576796 DOI: 10.1124/Jpet.110.166850 | 0.383 | |||
| 2010 | Walentiny DM, Vann RE, Warner JA, King LS, Seltzman HH, Navarro HA, Twine CE, Thomas BF, Gilliam AF, Gilmour BP, Carroll FI, Wiley JL. Kappa opioid mediation of cannabinoid effects of the potent hallucinogen, salvinorin A, in rodents. Psychopharmacology. 210: 275-84. PMID 20354680 DOI: 10.1007/S00213-010-1827-6 | 0.838 | |||
| 2010 | Wiley JL, Burston JJ. Chronic Delta9-tetrahydrocannabinol during adolescence increases sensitivity to subsequent cannabinoid effects in delayed nonmatch-to-position in rats. Pharmacology, Biochemistry, and Behavior. 94: 516-23. PMID 19941884 DOI: 10.1016/J.Pbb.2009.11.006 | 0.372 | |||
| 2009 | Long JZ, Nomura DK, Vann RE, Walentiny DM, Booker L, Jin X, Burston JJ, Sim-Selley LJ, Lichtman AH, Wiley JL, Cravatt BF. Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo. Proceedings of the National Academy of Sciences of the United States of America. 106: 20270-5. PMID 19918051 DOI: 10.1073/Pnas.0909411106 | 0.813 | |||
| 2009 | Vann RE, Warner JA, Bushell K, Huffman JW, Martin BR, Wiley JL. Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. European Journal of Pharmacology. 615: 102-7. PMID 19470387 DOI: 10.1016/J.Ejphar.2009.05.010 | 0.628 | |||
| 2009 | Bisogno T, Burston JJ, Rai R, Allarà M, Saha B, Mahadevan A, Razdan RK, Wiley JL, Di Marzo V. Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol. Chemmedchem. 4: 946-50. PMID 19266526 DOI: 10.1002/Cmdc.200800442 | 0.338 | |||
| 2009 | Wiley JL, Evans RL. To breed or not to breed? Empirical evaluation of drug effects in adolescent rats. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 9-20. PMID 19041390 DOI: 10.1016/J.Ijdevneu.2008.11.002 | 0.363 | |||
| 2008 | Wiley JL, Evans RL. Evaluation of age and sex differences in locomotion and catalepsy during repeated administration of haloperidol and clozapine in adolescent and adult rats. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 58: 240-6. PMID 18790058 DOI: 10.1016/J.Phrs.2008.08.002 | 0.304 | |||
| 2008 | Nomura DK, Hudak CS, Ward AM, Burston JJ, Issa RS, Fisher KJ, Abood ME, Wiley JL, Lichtman AH, Casida JE. Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. Bioorganic & Medicinal Chemistry Letters. 18: 5875-8. PMID 18752948 DOI: 10.1016/J.Bmcl.2008.08.007 | 0.719 | |||
| 2008 | Wiley JL, Kendler SH, Burston JJ, Howard DR, Selley DE, Sim-Selley LJ. Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats. Neuropharmacology. 55: 1183-90. PMID 18708079 DOI: 10.1016/J.Neuropharm.2008.07.026 | 0.426 | |||
| 2008 | Burston JJ, Sim-Selley LJ, Harloe JP, Mahadevan A, Razdan RK, Selley DE, Wiley JL. N-arachidonyl maleimide potentiates the pharmacological and biochemical effects of the endocannabinoid 2-arachidonylglycerol through inhibition of monoacylglycerol lipase. The Journal of Pharmacology and Experimental Therapeutics. 327: 546-53. PMID 18682568 DOI: 10.1124/Jpet.108.141382 | 0.427 | |||
| 2008 | Vann RE, Gamage TF, Warner JA, Marshall EM, Taylor NL, Martin BR, Wiley JL. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and Alcohol Dependence. 94: 191-8. PMID 18206320 DOI: 10.1016/J.Drugalcdep.2007.11.017 | 0.788 | |||
| 2008 | McKinney DL, Cassidy MP, Collier LM, Martin BR, Wiley JL, Selley DE, Sim-Selley LJ. Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 324: 664-73. PMID 17967938 DOI: 10.1124/Jpet.107.130328 | 0.595 | |||
| 2008 | Wiley JL. Antipsychotic-induced suppression of locomotion in juvenile, adolescent and adult rats. European Journal of Pharmacology. 578: 216-21. PMID 17935710 DOI: 10.1016/J.Ejphar.2007.09.010 | 0.323 | |||
| 2008 | Huffman JW, Thompson AL, Wiley JL, Martin BR. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorganic & Medicinal Chemistry. 16: 322-35. PMID 17919913 DOI: 10.1016/J.Bmc.2007.09.033 | 0.523 | |||
| 2008 | Wiley JL, Evans RL, Grainger DB, Nicholson KL. Age-dependent differences in sensitivity and sensitization to cannabinoids and 'club drugs' in male adolescent and adult rats. Addiction Biology. 13: 277-86. PMID 17850418 DOI: 10.1111/J.1369-1600.2007.00077.X | 0.317 | |||
| 2007 | Bowen SE, Charlesworth JD, Tokarz ME, Wright MJ, Wiley JL. Decreased sensitivity in adolescent vs. adult rats to the locomotor activating effects of toluene. Neurotoxicology and Teratology. 29: 599-606. PMID 17869480 DOI: 10.1016/J.Ntt.2007.08.001 | 0.303 | |||
| 2007 | Bourne C, Roy S, Wiley JL, Martin BR, Thomas BF, Mahadevan A, Razdan RK. Novel, potent THC/anandamide (hybrid) analogs. Bioorganic & Medicinal Chemistry. 15: 7850-64. PMID 17827022 DOI: 10.1016/J.Bmc.2007.08.039 | 0.663 | |||
| 2007 | Crocker PJ, Mahadevan A, Wiley JL, Martin BR, Razdan RK. The role of fluorine substitution in the structure-activity relationships (SAR) of classical cannabinoids. Bioorganic & Medicinal Chemistry Letters. 17: 1504-7. PMID 17257842 DOI: 10.1016/J.Bmcl.2007.01.006 | 0.451 | |||
| 2007 | Niyuhire F, Varvel SA, Thorpe AJ, Stokes RJ, Wiley JL, Lichtman AH. The disruptive effects of the CB1 receptor antagonist rimonabant on extinction learning in mice are task-specific. Psychopharmacology. 191: 223-31. PMID 17211653 DOI: 10.1007/S00213-006-0650-6 | 0.744 | |||
| 2007 | Wiley JL, O'connell MM, Tokarz ME, Wright MJ. Pharmacological effects of acute and repeated administration of Delta(9)-tetrahydrocannabinol in adolescent and adult rats. The Journal of Pharmacology and Experimental Therapeutics. 320: 1097-105. PMID 17172531 DOI: 10.1124/Jpet.106.108126 | 0.34 | |||
| 2007 | Vann RE, Cook CD, Martin BR, Wiley JL. Cannabimimetic properties of ajulemic acid. The Journal of Pharmacology and Experimental Therapeutics. 320: 678-86. PMID 17105826 DOI: 10.1124/Jpet.106.111625 | 0.643 | |||
| 2006 | Wright MJ, Vann RE, Gamage TF, Damaj MI, Wiley JL. Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats. Pharmacology, Biochemistry, and Behavior. 85: 507-13. PMID 17112574 DOI: 10.1016/J.Pbb.2006.09.020 | 0.767 | |||
| 2006 | Wiley JL, Razdan RK, Martin BR. Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. Life Sciences. 80: 24-35. PMID 16978656 DOI: 10.1016/J.Lfs.2006.08.017 | 0.601 | |||
| 2006 | Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5432-5. PMID 16889960 DOI: 10.1016/J.Bmcl.2006.07.051 | 0.503 | |||
| 2006 | Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1230-9. PMID 16757541 DOI: 10.1124/Jpet.106.104109 | 0.644 | |||
| 2006 | Varvel SA, Wiley JL, Yang R, Bridgen DT, Long K, Lichtman AH, Martin BR. Interactions between THC and cannabidiol in mouse models of cannabinoid activity. Psychopharmacology. 186: 226-34. PMID 16572263 DOI: 10.1007/S00213-006-0356-9 | 0.782 | |||
| 2006 | Marriott KS, Huffman JW, Wiley JL, Martin BR. Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor. Bioorganic & Medicinal Chemistry. 14: 2386-97. PMID 16321538 DOI: 10.1016/J.Bmc.2005.11.023 | 0.486 | |||
| 2006 | Ligresti A, Cascio MG, Pryce G, Kulasegram S, Beletskaya I, De Petrocellis L, Saha B, Mahadevan A, Visintin C, Wiley JL, Baker D, Martin BR, Razdan RK, Di Marzo V. New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. British Journal of Pharmacology. 147: 83-91. PMID 16284631 DOI: 10.1038/Sj.Bjp.0706418 | 0.419 | |||
| 2006 | Huffman JW, Bushell SM, Joshi SN, Wiley JL, Martin BR. Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 14: 247-62. PMID 16165365 DOI: 10.1016/J.Bmc.2005.08.013 | 0.512 | |||
| 2005 | Damaj MI, Wiley JL, Martin BR, Papke RL. In vivo characterization of a novel inhibitor of CNS nicotinic receptors. European Journal of Pharmacology. 521: 43-8. PMID 16181622 DOI: 10.1016/J.Ejphar.2005.06.056 | 0.557 | |||
| 2005 | Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, Cassidy MP, Wiley JL, Martin BR. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorganic & Medicinal Chemistry Letters. 15: 4110-3. PMID 16005223 DOI: 10.1016/J.Bmcl.2005.06.008 | 0.533 | |||
| 2005 | Wiley JL, Burston JJ, Leggett DC, Alekseeva OO, Razdan RK, Mahadevan A, Martin BR. CB1 cannabinoid receptor-mediated modulation of food intake in mice. British Journal of Pharmacology. 145: 293-300. PMID 15778743 DOI: 10.1038/Sj.Bjp.0706157 | 0.57 | |||
| 2005 | Wiley JL, Smith FL, Razdan RK, Dewey WL. Task specificity of cross-tolerance between Delta9-tetrahydrocannabinol and anandamide analogs in mice. European Journal of Pharmacology. 510: 59-68. PMID 15740725 DOI: 10.1016/J.Ejphar.2005.01.006 | 0.617 | |||
| 2005 | Huffman JW, Zengin G, Wu MJ, Lu J, Hynd G, Bushell K, Thompson AL, Bushell S, Tartal C, Hurst DP, Reggio PH, Selley DE, Cassidy MP, Wiley JL, Martin BR. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists. Bioorganic & Medicinal Chemistry. 13: 89-112. PMID 15582455 DOI: 10.1016/J.Bmc.2004.09.050 | 0.537 | |||
| 2005 | Alekseeva OO, Mahadevan A, Wiley JL, Martin BR, Razdan RK. Synthesis of novel 5-substituted pyrazole derivatives as cannabinoid antagonists Tetrahedron Letters. 46: 2159-2161. DOI: 10.1016/J.Tetlet.2005.01.165 | 0.408 | |||
| 2004 | Martin BR, Wiley JL. Mechanism of action of cannabinoids: how it may lead to treatment of cachexia, emesis, and pain. The Journal of Supportive Oncology. 2: 305-14; discussion 3. PMID 15357514 | 0.356 | |||
| 2004 | Wiley JL, LaVecchia KL, Karp NE, Kulasegram S, Mahadevan A, Razdan RK, Martin BR. A comparison of the discriminative stimulus effects of delta(9)-tetrahydrocannabinol and O-1812, a potent and metabolically stable anandamide analog, in rats. Experimental and Clinical Psychopharmacology. 12: 173-9. PMID 15301634 DOI: 10.1037/1064-1297.12.3.173 | 0.522 | |||
| 2004 | Wiley JL, Compton AD. Progressive ratio performance following challenge with antipsychotics, amphetamine, or NMDA antagonists in adult rats treated perinatally with phencyclidine. Psychopharmacology. 177: 170-7. PMID 15243736 DOI: 10.1007/S00213-004-1936-1 | 0.355 | |||
| 2004 | Wiley JL, Balster RL. Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats. Life Sciences. 75: 141-51. PMID 15120567 DOI: 10.1016/J.Lfs.2003.11.027 | 0.413 | |||
| 2004 | Baskfield CY, Martin BR, Wiley JL. Differential effects of delta9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice. The Journal of Pharmacology and Experimental Therapeutics. 309: 86-91. PMID 14718593 DOI: 10.1124/Jpet.103.055376 | 0.806 | |||
| 2003 | Wiley JL, Bühler KG, Lavecchia KL, Johnson KM. Pharmacological challenge reveals long-term effects of perinatal phencyclidine on delayed spatial alternation in rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 27: 867-73. PMID 12921921 DOI: 10.1016/S0278-5846(03)00146-5 | 0.349 | |||
| 2003 | Wiley JL, Martin BR. Cannabinoid pharmacological properties common to other centrally acting drugs. European Journal of Pharmacology. 471: 185-93. PMID 12826237 DOI: 10.1016/S0014-2999(03)01856-9 | 0.634 | |||
| 2003 | Wiley JL, Bale AS, Balster RL. Evaluation of toluene dependence and cross-sensitization to diazepam. Life Sciences. 72: 3023-33. PMID 12706489 DOI: 10.1016/S0024-3205(03)00233-9 | 0.39 | |||
| 2003 | Huffman JW, Miller JR, Liddle J, Yu S, Thomas BF, Wiley JL, Martin BR. Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 11: 1397-410. PMID 12628666 DOI: 10.1016/S0968-0896(02)00649-1 | 0.663 | |||
| 2003 | Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR. 3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor. Bioorganic & Medicinal Chemistry. 11: 539-49. PMID 12538019 DOI: 10.1016/S0968-0896(02)00451-0 | 0.501 | |||
| 2003 | Wiley JL, Harvey SA, Balster RL, Nicholson KL. Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats. Psychopharmacology. 165: 378-85. PMID 12459931 DOI: 10.1007/S00213-002-1297-6 | 0.371 | |||
| 2002 | Wiley JL, Martin BR. Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes. Chemistry and Physics of Lipids. 121: 57-63. PMID 12505690 DOI: 10.1016/S0009-3084(02)00146-9 | 0.576 | |||
| 2002 | Huffman JW, Bushell SM, Miller JR, Wiley JL, Martin BR. 1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 10: 4119-29. PMID 12413866 DOI: 10.1016/S0968-0896(02)00331-0 | 0.518 | |||
| 2002 | Wiley JL, Jefferson RG, Griffin G, Liddle J, Yu S, Huffman JW, Martin BR. Paradoxical pharmacological effects of deoxy-tetrahydrocannabinol analogs lacking high CB1 receptor affinity. Pharmacology. 66: 89-99. PMID 12207116 DOI: 10.1159/000065631 | 0.634 | |||
| 2002 | Wiley JL, Lavecchia KL, Martin BR, Damaj MI. Nicotine-like discriminative stimulus effects of bupropion in rats. Experimental and Clinical Psychopharmacology. 10: 129-35. PMID 12022798 DOI: 10.1037//1064-1297.10.2.129 | 0.517 | |||
| 2002 | Wiley JL, Beletskaya ID, Ng EW, Dai Z, Crocker PJ, Mahadevan A, Razdan RK, Martin BR. Resorcinol derivatives: a novel template for the development of cannabinoid CB(1)/CB(2) and CB(2)-selective agonists. The Journal of Pharmacology and Experimental Therapeutics. 301: 679-89. PMID 11961073 DOI: 10.1124/Jpet.301.2.679 | 0.602 | |||
| 2002 | Munzar P, Li H, Nicholson KL, Wiley JL, Balster RL. Enhancement of the discriminative stimulus effects of phencyclidine by the tetracycline antibiotics doxycycline and minocycline in rats. Psychopharmacology. 160: 331-6. PMID 11889503 DOI: 10.1007/s00213-001-0989-7 | 0.3 | |||
| 2002 | Martin BR, Jefferson RG, Winckler R, Wiley JL, Thomas BF, Crocker PJ, Williams W, Razdan RK. Assessment of structural commonality between tetrahydrocannabinol and anandamide. European Journal of Pharmacology. 435: 35-42. PMID 11790376 DOI: 10.1016/S0014-2999(01)01527-8 | 0.645 | |||
| 2001 | Wallace MJ, Wiley JL, Martin BR, DeLorenzo RJ. Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. European Journal of Pharmacology. 428: 51-7. PMID 11779037 DOI: 10.1016/S0014-2999(01)01243-2 | 0.591 | |||
| 2001 | Willmore CB, LaVecchia KL, Wiley JL. NMDA antagonists produce site-selective impairment of accuracy in a delayed nonmatch-to-sample task in rats. Neuropharmacology. 41: 916-27. PMID 11747896 DOI: 10.1016/S0028-3908(01)00143-5 | 0.363 | |||
| 2001 | Huffman JW, Lu J, Hynd G, Wiley JL, Martin BR. A pyridone analogue of traditional cannabinoids. A new class of selective ligands for the CB(2) receptor. Bioorganic & Medicinal Chemistry. 9: 2863-70. PMID 11597467 DOI: 10.1016/S0968-0896(01)00155-9 | 0.45 | |||
| 2001 | Wiley JL, Jefferson RG, Grier MC, Mahadevan A, Razdan RK, Martin BR. Novel pyrazole cannabinoids: insights into CB(1) receptor recognition and activation. The Journal of Pharmacology and Experimental Therapeutics. 296: 1013-22. PMID 11181936 | 0.579 | |||
| 2001 | Compton AD, Slemmer JE, Drew MR, Hyman JM, Golden KM, Balster RL, Wiley JL. Combinations of clozapine and phencyclidine: effects on drug discrimination and behavioral inhibition in rats. Neuropharmacology. 40: 289-97. PMID 11114408 DOI: 10.1016/S0028-3908(00)00126-X | 0.406 | |||
| 2001 | Wiley JL, Patrick GA, Dance ME, Meyer KB, Balster RL. Preclinical abuse potential assessment of the anticonvulsant zonisamide Drug Development Research. 54: 66-74. DOI: 10.1002/Ddr.1206 | 0.422 | |||
| 2000 | Wiley JL, Dewey MA, Jefferson RG, Winckler RL, Bridgen DT, Willoughby KA, Martin BR. Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. Life Sciences. 67: 1573-83. PMID 10983852 DOI: 10.1016/S0024-3205(00)00749-9 | 0.508 | |||
| 2000 | Wiley JL, Patrick GS, Crocker PC, Saha B, Razdan RK, Martin BR. Antinociceptive effects of tetrahydrocannabinol side chain analogs: dependence upon route of administration. European Journal of Pharmacology. 397: 319-26. PMID 10844130 DOI: 10.1016/S0014-2999(00)00259-4 | 0.437 | |||
| 2000 | Huffman JW, Lu J, Dai D, Kitaygorodskiy A, Wiley JL, Martin BR. Synthesis and pharmacology of a hybrid cannabinoid. Bioorganic & Medicinal Chemistry. 8: 439-47. PMID 10722167 DOI: 10.1016/S0968-0896(99)00305-3 | 0.454 | |||
| 1999 | Huffman JW, Liddle J, Yu S, Aung MM, Abood ME, Wiley JL, Martin BR. 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 7: 2905-14. PMID 10658595 DOI: 10.1016/S0968-0896(99)00219-9 | 0.695 | |||
| 1999 | Wiley JL, Martin BR. Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination. Pharmacology, Biochemistry, and Behavior. 64: 519-22. PMID 10548265 DOI: 10.1016/S0091-3057(99)00130-6 | 0.536 | |||
| 1999 | Wiley JL. Cannabis: discrimination of "internal bliss"? Pharmacology, Biochemistry, and Behavior. 64: 257-60. PMID 10515300 DOI: 10.1016/S0091-3057(99)00059-3 | 0.524 | |||
| 1999 | Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, Saha B, Razdan RK. Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists. The Journal of Pharmacology and Experimental Therapeutics. 290: 1065-79. PMID 10454479 | 0.508 | |||
| 1999 | Bowen SE, Wiley JL, Jones HE, Balster RL. Phencyclidine- and diazepam-like discriminative stimulus effects of inhalants in mice. Experimental and Clinical Psychopharmacology. 7: 28-37. PMID 10036607 DOI: 10.1037/1064-1297.7.1.28 | 0.407 | |||
| 1998 | Huffman JW, Liddle J, Duncan SG, Yu S, Martin BR, Wiley JL. Synthesis and pharmacology of the isomeric methylheptyl-delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 6: 2383-96. PMID 9925296 DOI: 10.1016/S0968-0896(98)80014-X | 0.404 | |||
| 1998 | Wiley JL, Compton AD, Holcomb JD, McCallum SE, Varvel SA, Porter JH, Balster RL. Effects of modulation of NMDA neurotransmission on response rate and duration in a conflict procedure in rats. Neuropharmacology. 37: 1527-34. PMID 9886675 DOI: 10.1016/S0028-3908(98)00152-X | 0.772 | |||
| 1998 | Liddle J, Huffman JW, Wiley JL, Martin BR. Enantioselective synthesis and pharmacology of 11-hydroxy-(1'S,2'R)-dimethylheptyl-delta 8-THC. Bioorganic & Medicinal Chemistry Letters. 8: 2223-6. PMID 9873517 DOI: 10.1016/S0960-894X(98)00385-0 | 0.37 | |||
| 1998 | Lichtman AH, Wiley JL, LaVecchia KL, Neviaser ST, Arthur DB, Wilson DM, Martin BR. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. European Journal of Pharmacology. 357: 139-48. PMID 9797029 DOI: 10.1016/S0014-2999(98)00558-5 | 0.65 | |||
| 1998 | Wiley JL, Ryan WJ, Razdan RK, Martin BR. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. European Journal of Pharmacology. 355: 113-8. PMID 9760024 DOI: 10.1016/S0014-2999(98)00502-0 | 0.519 | |||
| 1998 | Wiley JL, Compton DR, Dai D, Lainton JA, Phillips M, Huffman JW, Martin BR. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 285: 995-1004. PMID 9618400 | 0.49 | |||
| 1997 | Wiley JL, Golden KM, Ryan WJ, Balster RL, Razdan RK, Martin BR. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 58: 1139-43. PMID 9408225 DOI: 10.1016/S0091-3057(97)00327-4 | 0.519 | |||
| 1997 | Ryan WJ, Banner WK, Wiley JL, Martin BR, Razdan RK. Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. Journal of Medicinal Chemistry. 40: 3617-25. PMID 9357528 DOI: 10.1021/jm970212f | 0.396 | |||
| 1997 | Huffman JW, Duncan SG, Wiley JL, Martin BR. Synthesis and pharmacology of the 1',2'-dimethylheptyl-Δ8-THC isomers: Exceptionally potent cannabinoids Bioorganic and Medicinal Chemistry Letters. 7: 2799-2804. DOI: 10.1016/S0960-894X(97)10086-5 | 0.394 | |||
| 1997 | Huffman JW, Lainton JAH, Banner WK, Duncan SG, Jordan RD, Yu S, Dai D, Martin BR, Wiley JL, Compton DR. Side chain methyl analogues of Δ8-THC Tetrahedron. 53: 1557-1576. DOI: 10.1016/S0040-4020(96)01134-9 | 0.371 | |||
| 1996 | Wiley JL, Compton DR, Gordon PM, Siegel C, Singer M, Dutta A, Lichtman AH, Balster RL, Razdan RK, Martin BR. Evaluation of agonist-antagonist properties of nitrogen mustard and cyano derivatives of delta 8-tetrahydrocannabinol. Neuropharmacology. 35: 1793-804. PMID 9076759 DOI: 10.1016/S0028-3908(96)00120-7 | 0.684 | |||
| 1996 | Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH. Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. Journal of Medicinal Chemistry. 39: 3875-7. PMID 8831752 DOI: 10.1021/Jm960394Y | 0.725 | |||
| 1996 | Wiley JL, James JR, Rosecrans JA. Discriminative stimulus properties of nicotine: Approaches to evaluating potential nicotinic receptor agonists and antagonists Drug Development Research. 38: 222-230. DOI: 10.1002/(Sici)1098-2299(199607/08)38:3/4<222::Aid-Ddr11>3.0.Co;2-0 | 0.367 | |||
| 1995 | Balster RL, Mansbach RS, Shelton KL, Nicholson KL, Grech DM, Wiley JL, Li H, Weber E. Behavioral pharmacology of two novel substituted quinoxalinedione glutamate antagonists. Behavioural Pharmacology. 6: 577-589. PMID 11224365 DOI: 10.1097/00008877-199508000-00018 | 0.422 | |||
| 1995 | Wiley JL, Cristello AF, Balster RL. Effects of site-selective NMDA receptor antagonists in an elevated plus-maze model of anxiety in mice. European Journal of Pharmacology. 294: 101-7. PMID 8788421 DOI: 10.1016/0014-2999(95)00506-4 | 0.307 | |||
| 1995 | Wiley JL, Huffman JW, Balster RL, Martin BR. Pharmacological specificity of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rhesus monkeys. Drug and Alcohol Dependence. 40: 81-6. PMID 8746928 DOI: 10.1016/0376-8716(95)01193-5 | 0.504 | |||
| 1995 | Rosecrans JA, Wiley JL, Bass CE, Karan LD. Nicotine-induced acute tolerance: studies involving schedule-controlled behavior. Brain Research Bulletin. 37: 359-62. PMID 7620908 DOI: 10.1016/0361-9230(95)00007-0 | 0.68 | |||
| 1995 | Barrett RL, Wiley JL, Balster RL, Martin BR. Pharmacological specificity of delta 9-tetrahydrocannabinol discrimination in rats. Psychopharmacology. 118: 419-24. PMID 7568628 DOI: 10.1007/Bf02245942 | 0.531 | |||
| 1995 | Wiley JL, Barrett RL, Lowe J, Balster RL, Martin BR. Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats. Neuropharmacology. 34: 669-76. PMID 7566504 DOI: 10.1016/0028-3908(95)00027-4 | 0.553 | |||
| 1995 | Wiley JL, Lowe JA, Balster RL, Martin BR. Antagonism of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rats and rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 275: 1-6. PMID 7562536 | 0.548 | |||
| 1994 | Wiley JL, Compton AD, Porter JH. Differential effects of clozapine and pimozide on fixed-ratio responding during repeated dosing. Pharmacology, Biochemistry, and Behavior. 48: 253-7. PMID 8029297 DOI: 10.1016/0091-3057(94)90524-X | 0.591 | |||
| 1993 | Wiley JL, Barrett RL, Balster RL, Martin BR. Tolerance to the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol. Behavioural Pharmacology. 4: 581-585. PMID 11224227 | 0.485 | |||
| 1993 | Wiley JL, Barrett RL, Britt DT, Balster RL, Martin BR. Discriminative stimulus effects of delta 9-tetrahydrocannabinol and delta 9-11-tetrahydrocannabinol in rats and rhesus monkeys. Neuropharmacology. 32: 359-65. PMID 8388551 DOI: 10.1016/0028-3908(93)90157-X | 0.502 | |||
| 1993 | Wiley JL, Compton AD, Porter JH. Effects of four antipsychotics on punished responding in rats. Pharmacology, Biochemistry, and Behavior. 45: 263-7. PMID 8101005 DOI: 10.1016/0091-3057(93)90237-N | 0.612 | |||
| 1993 | Wiley JL, Porter JH. Effects of serotonergic drugs in rats trained to discriminate clozapine from haloperidol Bulletin of the Psychonomic Society. 31: 94-96. DOI: 10.3758/Bf03334149 | 0.643 | |||
| 1993 | Wiley JL, Barrett RL, Balster RL, Martin BR. Tolerance to the discriminative stimulus effects of Δ9-tetrahydrocannabinol Behavioural Pharmacology. 4: 581-585. DOI: 10.1097/00008877-199312000-00004 | 0.478 | |||
| 1992 | Wiley JL, Porter JH. Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure. Pharmacology, Biochemistry, and Behavior. 43: 961-5. PMID 1448493 DOI: 10.1016/0091-3057(92)90433-G | 0.643 | |||
| 1992 | Balster RL, Wiley JL, Tokarz ME, Knisely JS. Effects of ethanol and toluene on fixed-ratio performance in short sleep and long sleep mice. Drug and Alcohol Dependence. 31: 65-75. PMID 1425215 DOI: 10.1016/0376-8716(92)90010-A | 0.309 | |||
| 1992 | Wiley JL, Porter JH, Compton AD, Balster RL. Antipunishment effects of acute and repeated administration of phencyclidine and NPC 12626 in rats. Life Sciences. 50: 1519-28. PMID 1349714 DOI: 10.1016/0024-3205(92)90142-C | 0.641 | |||
| 1990 | Wiley JL, Porter JH. Differential effects of haloperidol and clozapine on the reinforcing efficacy of food reward in an alleyway reacquisition paradigm. Pharmacology, Biochemistry, and Behavior. 36: 569-73. PMID 2377657 DOI: 10.1016/0091-3057(90)90257-I | 0.592 | |||
| 1989 | Porter JH, Wiley JL, Balster RL. Effects of phencyclidine-like drugs on punished behavior in rats. The Journal of Pharmacology and Experimental Therapeutics. 248: 997-1002. PMID 2539469 | 0.605 | |||
| 1989 | Wiley JL, Porter JH, Faw WR. Haloperidol blocks reacquisition of operant running during extinction following a single priming trial with food reward Bulletin of the Psychonomic Society. 27: 340-342. DOI: 10.3758/Bf03334621 | 0.567 | |||
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