| Year |
Citation |
Score |
| 2012 |
Wiley JL, Smith VJ, Chen J, Martin BR, Huffman JW. Synthesis and pharmacology of 1-alkyl-3-(1-naphthoyl)indoles: steric and electronic effects of 4- and 8-halogenated naphthoyl substituents. Bioorganic & Medicinal Chemistry. 20: 2067-81. PMID 22341572 DOI: 10.1016/J.Bmc.2012.01.038 |
0.609 |
|
| 2012 |
Wiley JL, Marusich JA, Martin BR, Huffman JW. 1-Pentyl-3-phenylacetylindoles and JWH-018 share in vivo cannabinoid profiles in mice. Drug and Alcohol Dependence. 123: 148-53. PMID 22127210 DOI: 10.1016/J.Drugalcdep.2011.11.001 |
0.583 |
|
| 2011 |
Wiley JL, Breivogel CS, Mahadevan A, Pertwee RG, Cascio MG, Bolognini D, Huffman JW, Walentiny DM, Vann RE, Razdan RK, Martin BR. Structural and pharmacological analysis of O-2050, a putative neutral cannabinoid CB(1) receptor antagonist. European Journal of Pharmacology. 651: 96-105. PMID 21114999 DOI: 10.1016/J.Ejphar.2010.10.085 |
0.814 |
|
| 2010 |
Huffman JW, Hepburn SA, Lyutenko N, Thompson AL, Wiley JL, Selley DE, Martin BR. 1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-Δ(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor. Bioorganic & Medicinal Chemistry. 18: 7809-15. PMID 20943404 DOI: 10.1016/J.Bmc.2010.09.061 |
0.592 |
|
| 2010 |
Huffman JW, Hepburn SA, Reggio PH, Hurst DP, Wiley JL, Martin BR. Synthesis and pharmacology of 1-methoxy analogs of CP-47,497. Bioorganic & Medicinal Chemistry. 18: 5475-82. PMID 20621488 DOI: 10.1016/J.Bmc.2010.06.054 |
0.604 |
|
| 2010 |
Carroll FI, Ma W, Deng L, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-(substituted phenyl)epibatidine analogues. Nicotinic partial agonists. Journal of Natural Products. 73: 306-12. PMID 20038125 DOI: 10.1021/Np9006124 |
0.398 |
|
| 2009 |
Vann RE, Warner JA, Bushell K, Huffman JW, Martin BR, Wiley JL. Discriminative stimulus properties of delta9-tetrahydrocannabinol (THC) in C57Bl/6J mice. European Journal of Pharmacology. 615: 102-7. PMID 19470387 DOI: 10.1016/J.Ejphar.2009.05.010 |
0.585 |
|
| 2008 |
Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of Pharmacology and Experimental Therapeutics. 326: 483-92. PMID 18451315 DOI: 10.1124/Jpet.108.138321 |
0.671 |
|
| 2008 |
Vann RE, Gamage TF, Warner JA, Marshall EM, Taylor NL, Martin BR, Wiley JL. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and Alcohol Dependence. 94: 191-8. PMID 18206320 DOI: 10.1016/J.Drugalcdep.2007.11.017 |
0.78 |
|
| 2008 |
McKinney DL, Cassidy MP, Collier LM, Martin BR, Wiley JL, Selley DE, Sim-Selley LJ. Dose-related differences in the regional pattern of cannabinoid receptor adaptation and in vivo tolerance development to delta9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 324: 664-73. PMID 17967938 DOI: 10.1124/Jpet.107.130328 |
0.635 |
|
| 2008 |
Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs. Bioorganic & Medicinal Chemistry. 16: 746-54. PMID 17964169 DOI: 10.1016/J.Bmc.2007.10.027 |
0.397 |
|
| 2008 |
Huffman JW, Thompson AL, Wiley JL, Martin BR. Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorganic & Medicinal Chemistry. 16: 322-35. PMID 17919913 DOI: 10.1016/J.Bmc.2007.09.033 |
0.602 |
|
| 2007 |
Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA. Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. Journal of Medicinal Chemistry. 50: 6383-91. PMID 17994682 DOI: 10.1021/Jm0704696 |
0.339 |
|
| 2007 |
Bourne C, Roy S, Wiley JL, Martin BR, Thomas BF, Mahadevan A, Razdan RK. Novel, potent THC/anandamide (hybrid) analogs. Bioorganic & Medicinal Chemistry. 15: 7850-64. PMID 17827022 DOI: 10.1016/J.Bmc.2007.08.039 |
0.517 |
|
| 2007 |
Gehani NC, Nalwalk JW, Razdan RK, Martin BR, Sun X, Wentland M, Abood ME, Hough LB. Significance of cannabinoid CB1 receptors in improgan antinociception. The Journal of Pain : Official Journal of the American Pain Society. 8: 850-60. PMID 17644043 DOI: 10.1016/J.Jpain.2007.05.015 |
0.439 |
|
| 2007 |
Niyuhire F, Varvel SA, Martin BR, Lichtman AH. Exposure to marijuana smoke impairs memory retrieval in mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 1067-75. PMID 17586723 DOI: 10.1124/Jpet.107.119594 |
0.777 |
|
| 2007 |
Varvel SA, Martin BR, Lichtman AH. Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine. Psychopharmacology. 193: 511-9. PMID 17497137 DOI: 10.1007/S00213-007-0811-2 |
0.774 |
|
| 2007 |
Naidu PS, Varvel SA, Ahn K, Cravatt BF, Martin BR, Lichtman AH. Evaluation of fatty acid amide hydrolase inhibition in murine models of emotionality. Psychopharmacology. 192: 61-70. PMID 17279376 DOI: 10.1007/S00213-006-0689-4 |
0.782 |
|
| 2007 |
Crocker PJ, Mahadevan A, Wiley JL, Martin BR, Razdan RK. The role of fluorine substitution in the structure-activity relationships (SAR) of classical cannabinoids. Bioorganic & Medicinal Chemistry Letters. 17: 1504-7. PMID 17257842 DOI: 10.1016/J.Bmcl.2007.01.006 |
0.565 |
|
| 2007 |
Pertwee RG, Thomas A, Stevenson LA, Ross RA, Varvel SA, Lichtman AH, Martin BR, Razdan RK. The psychoactive plant cannabinoid, Delta9-tetrahydrocannabinol, is antagonized by Delta8- and Delta9-tetrahydrocannabivarin in mice in vivo. British Journal of Pharmacology. 150: 586-94. PMID 17245367 DOI: 10.1038/Sj.Bjp.0707124 |
0.768 |
|
| 2007 |
Wise LE, Shelton CC, Cravatt BF, Martin BR, Lichtman AH. Assessment of anandamide's pharmacological effects in mice deficient of both fatty acid amide hydrolase and cannabinoid CB1 receptors. European Journal of Pharmacology. 557: 44-8. PMID 17217945 DOI: 10.1016/J.Ejphar.2006.11.002 |
0.794 |
|
| 2007 |
Vann RE, Cook CD, Martin BR, Wiley JL. Cannabimimetic properties of ajulemic acid. The Journal of Pharmacology and Experimental Therapeutics. 320: 678-86. PMID 17105826 DOI: 10.1124/Jpet.106.111625 |
0.657 |
|
| 2007 |
Ivy Carroll F, Ma W, Navarro HA, Abraham P, Wolckenhauer SA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs. Bioorganic & Medicinal Chemistry. 15: 678-85. PMID 17098430 DOI: 10.1016/J.Bmc.2006.10.061 |
0.34 |
|
| 2007 |
Samudre S, Lattanzio FA, Martin BR, Castillo I, Hosseini A, Frazier M, Williams PB. Ocular Pharmacokinetics and Pharmacodynamics of Synthetic Cannabinoid, O‐1812, in a Perfused Rat Eye Model The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A417-C |
0.493 |
|
| 2006 |
Wiley JL, Razdan RK, Martin BR. Evaluation of the role of the arachidonic acid cascade in anandamide's in vivo effects in mice. Life Sciences. 80: 24-35. PMID 16978656 DOI: 10.1016/J.Lfs.2006.08.017 |
0.573 |
|
| 2006 |
Wilson DM, Varvel SA, Harloe JP, Martin BR, Lichtman AH. SR 141716 (Rimonabant) precipitates withdrawal in marijuana-dependent mice. Pharmacology, Biochemistry, and Behavior. 85: 105-13. PMID 16934319 DOI: 10.1016/J.Pbb.2006.07.018 |
0.795 |
|
| 2006 |
Huffman JW, Padgett LW, Isherwood ML, Wiley JL, Martin BR. 1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5432-5. PMID 16889960 DOI: 10.1016/J.Bmcl.2006.07.051 |
0.596 |
|
| 2006 |
Sim-Selley LJ, Schechter NS, Rorrer WK, Dalton GD, Hernandez J, Martin BR, Selley DE. Prolonged recovery rate of CB1 receptor adaptation after cessation of long-term cannabinoid administration. Molecular Pharmacology. 70: 986-96. PMID 16760363 DOI: 10.1124/Mol.105.019612 |
0.396 |
|
| 2006 |
Martin BR, Wiley JL, Beletskaya I, Sim-Selley LJ, Smith FL, Dewey WL, Cottney J, Adams J, Baker J, Hill D, Saha B, Zerkowski J, Mahadevan A, Razdan RK. Pharmacological characterization of novel water-soluble cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 318: 1230-9. PMID 16757541 DOI: 10.1124/Jpet.106.104109 |
0.638 |
|
| 2006 |
Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes. Journal of Medicinal Chemistry. 49: 3244-50. PMID 16722642 DOI: 10.1021/Jm060122N |
0.375 |
|
| 2006 |
Varvel SA, Wiley JL, Yang R, Bridgen DT, Long K, Lichtman AH, Martin BR. Interactions between THC and cannabidiol in mouse models of cannabinoid activity. Psychopharmacology. 186: 226-34. PMID 16572263 DOI: 10.1007/S00213-006-0356-9 |
0.805 |
|
| 2006 |
Abdrakhmanova GR, Damaj MI, Carroll FI, Martin BR. 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs. Molecular Pharmacology. 69: 1945-52. PMID 16505153 DOI: 10.1124/Mol.105.021782 |
0.357 |
|
| 2006 |
Blair RE, Deshpande LS, Sombati S, Falenski KW, Martin BR, DeLorenzo RJ. Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus. The Journal of Pharmacology and Experimental Therapeutics. 317: 1072-8. PMID 16469864 DOI: 10.1124/Jpet.105.100354 |
0.371 |
|
| 2006 |
Bisogno T, Cascio MG, Saha B, Mahadevan A, Urbani P, Minassi A, Appendino G, Saturnino C, Martin B, Razdan R, Di Marzo V. Development of the first potent and specific inhibitors of endocannabinoid biosynthesis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1761: 205-212. PMID 16466961 DOI: 10.1016/J.Bbalip.2005.12.009 |
0.313 |
|
| 2006 |
Grabus SD, Martin BR, Brown SE, Damaj MI. Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists. Psychopharmacology. 184: 456-63. PMID 16463055 DOI: 10.1007/S00213-006-0305-7 |
0.369 |
|
| 2006 |
Marriott KS, Huffman JW, Wiley JL, Martin BR. Synthesis and pharmacology of 11-nor-1-methoxy-9-hydroxyhexahydrocannabinols and 11-nor-1-deoxy-9-hydroxyhexahydrocannabinols: new selective ligands for the cannabinoid CB2 receptor. Bioorganic & Medicinal Chemistry. 14: 2386-97. PMID 16321538 DOI: 10.1016/J.Bmc.2005.11.023 |
0.586 |
|
| 2006 |
Ligresti A, Cascio MG, Pryce G, Kulasegram S, Beletskaya I, De Petrocellis L, Saha B, Mahadevan A, Visintin C, Wiley JL, Baker D, Martin BR, Razdan RK, Di Marzo V. New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis. British Journal of Pharmacology. 147: 83-91. PMID 16284631 DOI: 10.1038/Sj.Bjp.0706418 |
0.548 |
|
| 2006 |
Huffman JW, Bushell SM, Joshi SN, Wiley JL, Martin BR. Enantioselective synthesis of 1-methoxy- and 1-deoxy-2'-methyl-delta8-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 14: 247-62. PMID 16165365 DOI: 10.1016/J.Bmc.2005.08.013 |
0.601 |
|
| 2006 |
Lichtman AH, Martin BR. Understanding the pharmacology and physiology of cannabis dependence Cannabis Dependence: Its Nature, Consequences, and Treatment. 37-57. DOI: 10.1017/CBO9780511544248.005 |
0.581 |
|
| 2005 |
Lichtman AH, Martin BR. Cannabinoid tolerance and dependence. Handbook of Experimental Pharmacology. 691-717. PMID 16596793 DOI: 10.1007/3-540-26573-2_24 |
0.621 |
|
| 2005 |
Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues. Journal of Medicinal Chemistry. 48: 7491-5. PMID 16279810 DOI: 10.1021/Jm058243V |
0.365 |
|
| 2005 |
Damaj MI, Wiley JL, Martin BR, Papke RL. In vivo characterization of a novel inhibitor of CNS nicotinic receptors. European Journal of Pharmacology. 521: 43-8. PMID 16181622 DOI: 10.1016/J.Ejphar.2005.06.056 |
0.543 |
|
| 2005 |
Huffman JW, Szklennik PV, Almond A, Bushell K, Selley DE, He H, Cassidy MP, Wiley JL, Martin BR. 1-Pentyl-3-phenylacetylindoles, a new class of cannabimimetic indoles. Bioorganic & Medicinal Chemistry Letters. 15: 4110-3. PMID 16005223 DOI: 10.1016/J.Bmcl.2005.06.008 |
0.604 |
|
| 2005 |
Varvel SA, Bridgen DT, Tao Q, Thomas BF, Martin BR, Lichtman AH. Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice. The Journal of Pharmacology and Experimental Therapeutics. 314: 329-37. PMID 15831444 DOI: 10.1124/Jpet.104.080739 |
0.804 |
|
| 2005 |
Wiley JL, Burston JJ, Leggett DC, Alekseeva OO, Razdan RK, Mahadevan A, Martin BR. CB1 cannabinoid receptor-mediated modulation of food intake in mice. British Journal of Pharmacology. 145: 293-300. PMID 15778743 DOI: 10.1038/Sj.Bjp.0706157 |
0.554 |
|
| 2005 |
Huffman JW, Zengin G, Wu MJ, Lu J, Hynd G, Bushell K, Thompson AL, Bushell S, Tartal C, Hurst DP, Reggio PH, Selley DE, Cassidy MP, Wiley JL, Martin BR. Structure-activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB(1) and CB(2) receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB(2) receptor agonists. Bioorganic & Medicinal Chemistry. 13: 89-112. PMID 15582455 DOI: 10.1016/J.Bmc.2004.09.050 |
0.612 |
|
| 2005 |
Alekseeva OO, Mahadevan A, Wiley JL, Martin BR, Razdan RK. Synthesis of novel 5-substituted pyrazole derivatives as cannabinoid antagonists Tetrahedron Letters. 46: 2159-2161. DOI: 10.1016/J.Tetlet.2005.01.165 |
0.546 |
|
| 2004 |
Damaj MI, Hunter RG, Martin BR, Kuhar MJ. Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice. Brain Research. 1024: 146-9. PMID 15451376 DOI: 10.1016/J.Brainres.2004.07.058 |
0.365 |
|
| 2004 |
Martin BR, Wiley JL. Mechanism of action of cannabinoids: how it may lead to treatment of cachexia, emesis, and pain. The Journal of Supportive Oncology. 2: 305-14; discussion 3. PMID 15357514 |
0.444 |
|
| 2004 |
Damaj MI, Carroll FI, Eaton JB, Navarro HA, Blough BE, Mirza S, Lukas RJ, Martin BR. Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors. Molecular Pharmacology. 66: 675-82. PMID 15322260 DOI: 10.1124/Mol.104.001313 |
0.356 |
|
| 2004 |
Carroll FI, Ware R, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues. Novel nicotinic antagonist. Journal of Medicinal Chemistry. 47: 4588-94. PMID 15317468 DOI: 10.1021/Jm040078G |
0.424 |
|
| 2004 |
Wiley JL, LaVecchia KL, Karp NE, Kulasegram S, Mahadevan A, Razdan RK, Martin BR. A comparison of the discriminative stimulus effects of delta(9)-tetrahydrocannabinol and O-1812, a potent and metabolically stable anandamide analog, in rats. Experimental and Clinical Psychopharmacology. 12: 173-9. PMID 15301634 DOI: 10.1037/1064-1297.12.3.173 |
0.557 |
|
| 2004 |
Bass CE, Welch SP, Martin BR. Reversal of delta 9-tetrahydrocannabinol-induced tolerance by specific kinase inhibitors. European Journal of Pharmacology. 496: 99-108. PMID 15288581 DOI: 10.1016/J.Ejphar.2004.06.009 |
0.628 |
|
| 2004 |
Selley DE, Cassidy MP, Martin BR, Sim-Selley LJ. Long-term administration of Delta9-tetrahydrocannabinol desensitizes CB1-, adenosine A1-, and GABAB-mediated inhibition of adenylyl cyclase in mouse cerebellum. Molecular Pharmacology. 66: 1275-84. PMID 15286206 DOI: 10.1124/Mol.104.000604 |
0.377 |
|
| 2004 |
Martin BR, Sim-Selley LJ, Selley DE. Signaling pathways involved in the development of cannabinoid tolerance. Trends in Pharmacological Sciences. 25: 325-30. PMID 15165748 DOI: 10.1016/J.Tips.2004.04.005 |
0.339 |
|
| 2004 |
Baskfield CY, Martin BR, Wiley JL. Differential effects of delta9-tetrahydrocannabinol and methanandamide in CB1 knockout and wild-type mice. The Journal of Pharmacology and Experimental Therapeutics. 309: 86-91. PMID 14718593 DOI: 10.1124/Jpet.103.055376 |
0.797 |
|
| 2003 |
Simsek R, Chang-Fong J, Lee M, Dukat M, Imad Damaj M, Martin BR, Glennon RA. Quaternary ammonium 3-(aminoethoxy)pyridines as antinociceptive agents. Bioorganic & Medicinal Chemistry Letters. 13: 2917-20. PMID 14611857 DOI: 10.1016/S0960-894X(03)00585-7 |
0.413 |
|
| 2003 |
Wallace MJ, Blair RE, Falenski KW, Martin BR, DeLorenzo RJ. The endogenous cannabinoid system regulates seizure frequency and duration in a model of temporal lobe epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 307: 129-37. PMID 12954810 DOI: 10.1124/Jpet.103.051920 |
0.308 |
|
| 2003 |
Damaj MI, Martin BR, Kuhar MJ. Antinociceptive effects of supraspinal rat cart (55-102) peptide in mice. Brain Research. 983: 233-6. PMID 12914986 DOI: 10.1016/S0006-8993(03)03094-4 |
0.34 |
|
| 2003 |
Wiley JL, Martin BR. Cannabinoid pharmacological properties common to other centrally acting drugs. European Journal of Pharmacology. 471: 185-93. PMID 12826237 DOI: 10.1016/S0014-2999(03)01856-9 |
0.618 |
|
| 2003 |
Huffman JW, Miller JR, Liddle J, Yu S, Thomas BF, Wiley JL, Martin BR. Structure-activity relationships for 1',1'-dimethylalkyl-Delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 11: 1397-410. PMID 12628666 DOI: 10.1016/S0968-0896(02)00649-1 |
0.599 |
|
| 2003 |
Offertáler L, Mo FM, Bátkai S, Liu J, Begg M, Razdan RK, Martin BR, Bukoski RD, Kunos G. Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor. Molecular Pharmacology. 63: 699-705. PMID 12606780 DOI: 10.1124/Mol.63.3.699 |
0.387 |
|
| 2003 |
Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR. 3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor. Bioorganic & Medicinal Chemistry. 11: 539-49. PMID 12538019 DOI: 10.1016/S0968-0896(02)00451-0 |
0.594 |
|
| 2003 |
Breivogel CS, Scates SM, Beletskaya IO, Lowery OB, Aceto MD, Martin BR. The effects of delta9-tetrahydrocannabinol physical dependence on brain cannabinoid receptors. European Journal of Pharmacology. 459: 139-50. PMID 12524139 DOI: 10.1016/S0014-2999(02)02854-6 |
0.439 |
|
| 2003 |
Darmani NA, Sim-Selley LJ, Martin BR, Janoyan JJ, Crim JL, Parekh B, Breivogel CS. Antiemetic and motor-depressive actions of CP55,940: cannabinoid CB1 receptor characterization, distribution, and G-protein activation. European Journal of Pharmacology. 459: 83-95. PMID 12505537 DOI: 10.1016/S0014-2999(02)02815-7 |
0.426 |
|
| 2002 |
Wiley JL, Martin BR. Cannabinoid pharmacology: implications for additional cannabinoid receptor subtypes. Chemistry and Physics of Lipids. 121: 57-63. PMID 12505690 DOI: 10.1016/S0009-3084(02)00146-9 |
0.644 |
|
| 2002 |
Huffman JW, Bushell SM, Miller JR, Wiley JL, Martin BR. 1-Methoxy-, 1-deoxy-11-hydroxy- and 11-hydroxy-1-methoxy-Delta(8)-tetrahydrocannabinols: new selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 10: 4119-29. PMID 12413866 DOI: 10.1016/S0968-0896(02)00331-0 |
0.605 |
|
| 2002 |
Lichtman AH, Martin BR. Marijuana withdrawal syndrome in the animal model. Journal of Clinical Pharmacology. 42: 20S-27S. PMID 12412832 DOI: 10.1002/J.1552-4604.2002.Tb05999.X |
0.672 |
|
| 2002 |
Bass CE, Griffin G, Grier M, Mahadevan A, Razdan RK, Martin BR. SR-141716A-induced stimulation of locomotor activity. A structure-activity relationship study. Pharmacology, Biochemistry, and Behavior. 74: 31-40. PMID 12376150 DOI: 10.1016/S0091-3057(02)00945-0 |
0.676 |
|
| 2002 |
Carroll FI, Lee JR, Navarro HA, Ma W, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2',3'-disubstituted 5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes: epibatidine analogues. Journal of Medicinal Chemistry. 45: 4755-61. PMID 12361403 DOI: 10.1021/Jm0202268 |
0.393 |
|
| 2002 |
Dukat M, El-Zahabi M, Ferretti G, Damaj MI, Martin BR, Young R, Glennon RA. (-)6-n-Propylnicotine antagonizes the antinociceptive effects of (-)nicotine. Bioorganic & Medicinal Chemistry Letters. 12: 3005-7. PMID 12270194 DOI: 10.1016/S0960-894X(02)00614-5 |
0.39 |
|
| 2002 |
Sim-Selley LJ, Martin BR. Effect of chronic administration of R-(+)-[2,3-Dihydro-5-methyl-3-[(morpholinyl)methyl]pyrrolo[1,2,3-de]-1,4-benzoxazinyl]-(1-naphthalenyl)methanone mesylate (WIN55,212-2) or delta(9)-tetrahydrocannabinol on cannabinoid receptor adaptation in mice. The Journal of Pharmacology and Experimental Therapeutics. 303: 36-44. PMID 12235230 DOI: 10.1124/Jpet.102.035618 |
0.484 |
|
| 2002 |
Wiley JL, Jefferson RG, Griffin G, Liddle J, Yu S, Huffman JW, Martin BR. Paradoxical pharmacological effects of deoxy-tetrahydrocannabinol analogs lacking high CB1 receptor affinity. Pharmacology. 66: 89-99. PMID 12207116 DOI: 10.1159/000065631 |
0.645 |
|
| 2002 |
McKallip RJ, Lombard C, Martin BR, Nagarkatti M, Nagarkatti PS. Delta(9)-tetrahydrocannabinol-induced apoptosis in the thymus and spleen as a mechanism of immunosuppression in vitro and in vivo. The Journal of Pharmacology and Experimental Therapeutics. 302: 451-65. PMID 12130702 DOI: 10.1124/Jpet.102.033506 |
0.33 |
|
| 2002 |
Wilson DM, Peart J, Martin BR, Bridgen DT, Byron PR, Lichtman AH. Physiochemical and pharmacological characterization of a Delta(9)-THC aerosol generated by a metered dose inhaler. Drug and Alcohol Dependence. 67: 259-67. PMID 12127197 DOI: 10.1016/S0376-8716(02)00078-9 |
0.741 |
|
| 2002 |
McKallip RJ, Lombard C, Fisher M, Martin BR, Ryu S, Grant S, Nagarkatti PS, Nagarkatti M. Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease. Blood. 100: 627-34. PMID 12091357 DOI: 10.1182/Blood-2002-01-0098 |
0.327 |
|
| 2002 |
Lichtman AH, Varvel SA, Martin BR. Endocannabinoids in cognition and dependence. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 66: 269-85. PMID 12052042 DOI: 10.1054/Plef.2001.0351 |
0.77 |
|
| 2002 |
Howlett AC, Barth F, Bonner TI, Cabral G, Casellas P, Devane WA, Felder CC, Herkenham M, Mackie K, Martin BR, Mechoulam R, Pertwee RG. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacological Reviews. 54: 161-202. PMID 12037135 DOI: 10.1124/Pr.54.2.161 |
0.564 |
|
| 2002 |
Wiley JL, Lavecchia KL, Martin BR, Damaj MI. Nicotine-like discriminative stimulus effects of bupropion in rats. Experimental and Clinical Psychopharmacology. 10: 129-35. PMID 12022798 DOI: 10.1037//1064-1297.10.2.129 |
0.501 |
|
| 2002 |
Wiley JL, Beletskaya ID, Ng EW, Dai Z, Crocker PJ, Mahadevan A, Razdan RK, Martin BR. Resorcinol derivatives: a novel template for the development of cannabinoid CB(1)/CB(2) and CB(2)-selective agonists. The Journal of Pharmacology and Experimental Therapeutics. 301: 679-89. PMID 11961073 DOI: 10.1124/Jpet.301.2.679 |
0.621 |
|
| 2002 |
Di Marzo V, Griffin G, De Petrocellis L, Brandi I, Bisogno T, Williams W, Grier MC, Kulasegram S, Mahadevan A, Razdan RK, Martin BR. A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid. The Journal of Pharmacology and Experimental Therapeutics. 300: 984-91. PMID 11861807 DOI: 10.1124/Jpet.300.3.984 |
0.448 |
|
| 2002 |
Martin BR, Jefferson RG, Winckler R, Wiley JL, Thomas BF, Crocker PJ, Williams W, Razdan RK. Assessment of structural commonality between tetrahydrocannabinol and anandamide. European Journal of Pharmacology. 435: 35-42. PMID 11790376 DOI: 10.1016/S0014-2999(01)01527-8 |
0.579 |
|
| 2001 |
Wallace MJ, Wiley JL, Martin BR, DeLorenzo RJ. Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. European Journal of Pharmacology. 428: 51-7. PMID 11779037 DOI: 10.1016/S0014-2999(01)01243-2 |
0.575 |
|
| 2001 |
Carroll FI, Lee JR, Navarro HA, Brieaddy LE, Abraham P, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2-exo-2-(2'-substituted-3'-phenyl-5'-pyridinyl)-7-azabicyclo[2.2.1]heptanes. Novel nicotinic antagonist. Journal of Medicinal Chemistry. 44: 4039-41. PMID 11708907 DOI: 10.1021/Jm015561V |
0.427 |
|
| 2001 |
Huffman JW, Lu J, Hynd G, Wiley JL, Martin BR. A pyridone analogue of traditional cannabinoids. A new class of selective ligands for the CB(2) receptor. Bioorganic & Medicinal Chemistry. 9: 2863-70. PMID 11597467 DOI: 10.1016/S0968-0896(01)00155-9 |
0.563 |
|
| 2001 |
Varvel SA, Hamm RJ, Martin BR, Lichtman AH. Differential effects of delta 9-THC on spatial reference and working memory in mice. Psychopharmacology. 157: 142-50. PMID 11594438 DOI: 10.1007/s002130100780 |
0.752 |
|
| 2001 |
Lichtman AH, Sheikh SM, Loh HH, Martin BR. Opioid and cannabinoid modulation of precipitated withdrawal in delta(9)-tetrahydrocannabinol and morphine-dependent mice. The Journal of Pharmacology and Experimental Therapeutics. 298: 1007-14. PMID 11504797 |
0.658 |
|
| 2001 |
Cravatt BF, Demarest K, Patricelli MP, Bracey MH, Giang DK, Martin BR, Lichtman AH. Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase. Proceedings of the National Academy of Sciences of the United States of America. 98: 9371-6. PMID 11470906 DOI: 10.1073/Pnas.161191698 |
0.68 |
|
| 2001 |
Lichtman AH, Fisher J, Martin BR. Precipitated cannabinoid withdrawal is reversed by Delta(9)-tetrahydrocannabinol or clonidine. Pharmacology, Biochemistry, and Behavior. 69: 181-8. PMID 11420084 DOI: 10.1016/S0091-3057(01)00514-7 |
0.675 |
|
| 2001 |
Breivogel CS, Griffin G, Di Marzo V, Martin BR. Evidence for a new G protein-coupled cannabinoid receptor in mouse brain. Molecular Pharmacology. 60: 155-63. PMID 11408610 DOI: 10.1124/Mol.60.1.155 |
0.387 |
|
| 2001 |
Lichtman AH, Poklis JL, Poklis A, Wilson DM, Martin BR. The pharmacological activity of inhalation exposure to marijuana smoke in mice. Drug and Alcohol Dependence. 63: 107-16. PMID 11376914 DOI: 10.1016/S0376-8716(00)00205-2 |
0.74 |
|
| 2001 |
Wiley JL, Jefferson RG, Grier MC, Mahadevan A, Razdan RK, Martin BR. Novel pyrazole cannabinoids: insights into CB(1) receptor recognition and activation. The Journal of Pharmacology and Experimental Therapeutics. 296: 1013-22. PMID 11181936 |
0.611 |
|
| 2001 |
Di Marzo V, Bisogno T, De Petrocellis L, Brandi I, Jefferson RG, Winckler RL, Davis JB, Dasse O, Mahadevan A, Razdan RK, Martin BR. Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands. Biochemical and Biophysical Research Communications. 281: 444-51. PMID 11181068 DOI: 10.1006/Bbrc.2001.4354 |
0.388 |
|
| 2001 |
Griffin G, Williams S, Aung MM, Razdan RK, Martin BR, Abood ME. Separation of cannabinoid receptor affinity and efficacy in delta-8-tetrahydrocannabinol side-chain analogues. British Journal of Pharmacology. 132: 525-35. PMID 11159703 DOI: 10.1038/Sj.Bjp.0703827 |
0.4 |
|
| 2000 |
Ferretti G, Dukat M, Giannella M, Piergentili A, Pigini M, Quaglia W, Damaj MI, Martin BR, Glennon RA. Chain-lengthened and imidazoline analogues of nicotine. Bioorganic & Medicinal Chemistry Letters. 10: 2665-8. PMID 11128647 DOI: 10.1016/S0960-894X(00)00541-2 |
0.346 |
|
| 2000 |
Di Marzo V, Breivogel CS, Tao Q, Bridgen DT, Razdan RK, Zimmer AM, Zimmer A, Martin BR. Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain. Journal of Neurochemistry. 75: 2434-44. PMID 11080195 DOI: 10.1046/J.1471-4159.2000.0752434.X |
0.446 |
|
| 2000 |
Damaj MI, Meyer EM, Martin BR. The antinociceptive effects of alpha7 nicotinic agonists in an acute pain model. Neuropharmacology. 39: 2785-91. PMID 11044748 DOI: 10.1016/S0028-3908(00)00139-8 |
0.374 |
|
| 2000 |
Di Marzo V, Breivogel C, Bisogno T, Melck D, Patrick G, Tao Q, Szallasi A, Razdan RK, Martin BR. Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide. European Journal of Pharmacology. 406: 363-74. PMID 11040343 DOI: 10.1016/S0014-2999(00)00687-7 |
0.466 |
|
| 2000 |
Mahadevan A, Siegel C, Martin BR, Abood ME, Beletskaya I, Razdan RK. Novel cannabinol probes for CB1 and CB2 cannabinoid receptors. Journal of Medicinal Chemistry. 43: 3778-85. PMID 11020293 DOI: 10.1021/Jm0001572 |
0.402 |
|
| 2000 |
Wiley JL, Dewey MA, Jefferson RG, Winckler RL, Bridgen DT, Willoughby KA, Martin BR. Influence of phenylmethylsulfonyl fluoride on anandamide brain levels and pharmacological effects. Life Sciences. 67: 1573-83. PMID 10983852 DOI: 10.1016/S0024-3205(00)00749-9 |
0.528 |
|
| 2000 |
Aung MM, Griffin G, Huffman JW, Wu M, Keel C, Yang B, Showalter VM, Abood ME, Martin BR. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB(1) and CB(2) receptor binding. Drug and Alcohol Dependence. 60: 133-40. PMID 10940540 DOI: 10.1016/S0376-8716(99)00152-0 |
0.354 |
|
| 2000 |
Bass CE, Martin BR. Time course for the induction and maintenance of tolerance to Delta(9)-tetrahydrocannabinol in mice. Drug and Alcohol Dependence. 60: 113-9. PMID 10940538 DOI: 10.1016/S0376-8716(99)00150-7 |
0.68 |
|
| 2000 |
Lichtman AH, Peart J, Poklis JL, Bridgen DT, Razdan RK, Wilson DM, Poklis A, Meng Y, Byron PR, Martin BR. Pharmacological evaluation of aerosolized cannabinoids in mice. European Journal of Pharmacology. 399: 141-9. PMID 10884513 DOI: 10.1016/S0014-2999(00)00321-6 |
0.815 |
|
| 2000 |
Wiley JL, Patrick GS, Crocker PC, Saha B, Razdan RK, Martin BR. Antinociceptive effects of tetrahydrocannabinol side chain analogs: dependence upon route of administration. European Journal of Pharmacology. 397: 319-26. PMID 10844130 DOI: 10.1016/S0014-2999(00)00259-4 |
0.579 |
|
| 2000 |
Huffman JW, Lu J, Dai D, Kitaygorodskiy A, Wiley JL, Martin BR. Synthesis and pharmacology of a hybrid cannabinoid. Bioorganic & Medicinal Chemistry. 8: 439-47. PMID 10722167 DOI: 10.1016/S0968-0896(99)00305-3 |
0.568 |
|
| 2000 |
Beardsley PM, Martin BR. Effects of the cannabinoid CB(1) receptor antagonist, SR141716A, after Delta(9)-tetrahydrocannabinol withdrawal. European Journal of Pharmacology. 387: 47-53. PMID 10633159 DOI: 10.1016/S0014-2999(99)00792-X |
0.405 |
|
| 1999 |
Huffman JW, Liddle J, Yu S, Aung MM, Abood ME, Wiley JL, Martin BR. 3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor. Bioorganic & Medicinal Chemistry. 7: 2905-14. PMID 10658595 DOI: 10.1016/S0968-0896(99)00219-9 |
0.606 |
|
| 1999 |
Járai Z, Wagner JA, Varga K, Lake KD, Compton DR, Martin BR, Zimmer AM, Bonner TI, Buckley NE, Mezey E, Razdan RK, Zimmer A, Kunos G. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 96: 14136-41. PMID 10570211 DOI: 10.1073/pnas.96.24.14136 |
0.31 |
|
| 1999 |
Wiley JL, Martin BR. Effects of SR141716A on diazepam substitution for delta9-tetrahydrocannabinol in rat drug discrimination. Pharmacology, Biochemistry, and Behavior. 64: 519-22. PMID 10548265 DOI: 10.1016/S0091-3057(99)00130-6 |
0.604 |
|
| 1999 |
Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. 128: 684-8. PMID 10516649 DOI: 10.1038/Sj.Bjp.0702806 |
0.388 |
|
| 1999 |
Flammia D, Dukat M, Damaj MI, Martin B, Glennon RA. Lobeline: Structure-affinity investigation of nicotinic acetylcholinergic receptor binding Journal of Medicinal Chemistry. 42: 3726-3731. PMID 10479304 DOI: 10.1021/Jm990286M |
0.364 |
|
| 1999 |
Martin BR, Jefferson R, Winckler R, Wiley JL, Huffman JW, Crocker PJ, Saha B, Razdan RK. Manipulation of the tetrahydrocannabinol side chain delineates agonists, partial agonists, and antagonists. The Journal of Pharmacology and Experimental Therapeutics. 290: 1065-79. PMID 10454479 |
0.558 |
|
| 1999 |
Griffin G, Wray EJ, Tao Q, McAllister SD, Rorrer WK, Aung MM, Martin BR, Abood ME. Evaluation of the cannabinoid CB2 receptor-selective antagonist, SR144528: further evidence for cannabinoid CB2 receptor absence in the rat central nervous system. European Journal of Pharmacology. 377: 117-25. PMID 10448934 DOI: 10.1016/S0014-2999(99)00402-1 |
0.376 |
|
| 1999 |
Ng EW, Aung MM, Abood ME, Martin BR, Razdan RK. Unique analogues of anandamide: arachidonyl ethers and carbamates and norarachidonyl carbamates and ureas. Journal of Medicinal Chemistry. 42: 1975-81. PMID 10354405 DOI: 10.1021/Jm980711W |
0.331 |
|
| 1999 |
Griffin G, Wray EJ, Rorrer WK, Crocker PJ, Ryan WJ, Saha B, Razdan RK, Martin BR, Abood ME. An investigation into the structural determinants of cannabinoid receptor ligand efficacy. British Journal of Pharmacology. 126: 1575-84. PMID 10323589 DOI: 10.1038/Sj.Bjp.0702469 |
0.349 |
|
| 1999 |
Meng Y, Dukat M, Bridgen DT, Martin BR, Lichtman AH. Pharmacological effects of methamphetamine and other stimulants via inhalation exposure. Drug and Alcohol Dependence. 53: 111-20. PMID 10080037 DOI: 10.1016/S0376-8716(98)00120-3 |
0.786 |
|
| 1999 |
Crocker PJ, Saha B, Ryan WJ, Wiley JL, Martin BR, Ross RA, Pertwee RG, Razdan RK. Development of agonists, partial agonists and antagonists in the Δ8-Tetrahydrocannabinol series Tetrahedron. 55: 13907-13926. DOI: 10.1016/S0040-4020(99)00849-2 |
0.373 |
|
| 1999 |
Levin ED, Imad Damaj M, Glassco W, May EL, Martin BR. Bridged nicotine, isonicotine, and norisonicotine effects on working memory performance of rats in the radial-arm maze Drug Development Research. 46: 107-111. DOI: 10.1002/(Sici)1098-2299(199902)46:2<107::Aid-Ddr3>3.0.Co;2-C |
0.345 |
|
| 1998 |
Martin BR, Lichtman AH. Cannabinoid transmission and pain perception. Neurobiology of Disease. 5: 447-61. PMID 9974177 DOI: 10.1006/Nbdi.1998.0218 |
0.589 |
|
| 1998 |
Huffman JW, Liddle J, Duncan SG, Yu S, Martin BR, Wiley JL. Synthesis and pharmacology of the isomeric methylheptyl-delta8-tetrahydrocannabinols. Bioorganic & Medicinal Chemistry. 6: 2383-96. PMID 9925296 DOI: 10.1016/S0968-0896(98)80014-X |
0.546 |
|
| 1998 |
Liddle J, Huffman JW, Wiley JL, Martin BR. Enantioselective synthesis and pharmacology of 11-hydroxy-(1'S,2'R)-dimethylheptyl-delta 8-THC. Bioorganic & Medicinal Chemistry Letters. 8: 2223-6. PMID 9873517 DOI: 10.1016/S0960-894X(98)00385-0 |
0.518 |
|
| 1998 |
Lichtman AH, Wiley JL, LaVecchia KL, Neviaser ST, Arthur DB, Wilson DM, Martin BR. Effects of SR 141716A after acute or chronic cannabinoid administration in dogs. European Journal of Pharmacology. 357: 139-48. PMID 9797029 DOI: 10.1016/S0014-2999(98)00558-5 |
0.725 |
|
| 1998 |
Singer M, Ryan WJ, Saha B, Martin BR, Razdan RK. Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol. Journal of Medicinal Chemistry. 41: 4400-7. PMID 9784115 DOI: 10.1021/Jm9803875 |
0.309 |
|
| 1998 |
Wiley JL, Ryan WJ, Razdan RK, Martin BR. Evaluation of cannabimimetic effects of structural analogs of anandamide in rats. European Journal of Pharmacology. 355: 113-8. PMID 9760024 DOI: 10.1016/S0014-2999(98)00502-0 |
0.612 |
|
| 1998 |
Cook SA, Lowe JA, Martin BR. CB1 receptor antagonist precipitates withdrawal in mice exposed to Delta9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 285: 1150-6. PMID 9618417 |
0.333 |
|
| 1998 |
Wiley JL, Compton DR, Dai D, Lainton JA, Phillips M, Huffman JW, Martin BR. Structure-activity relationships of indole- and pyrrole-derived cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 285: 995-1004. PMID 9618400 |
0.548 |
|
| 1998 |
Adams IB, Compton DR, Martin BR. Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 284: 1209-17. PMID 9495885 |
0.32 |
|
| 1997 |
Wiley JL, Golden KM, Ryan WJ, Balster RL, Razdan RK, Martin BR. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. Pharmacology, Biochemistry, and Behavior. 58: 1139-43. PMID 9408225 DOI: 10.1016/S0091-3057(97)00327-4 |
0.613 |
|
| 1997 |
Compton DR, Martin BR. The effect of the enzyme inhibitor phenylmethylsulfonyl fluoride on the pharmacological effect of anandamide in the mouse model of cannabimimetic activity. The Journal of Pharmacology and Experimental Therapeutics. 283: 1138-43. PMID 9399986 |
0.329 |
|
| 1997 |
Wagner JA, Varga K, Ellis EF, Rzigalinski BA, Martin BR, Kunos G. Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock. Nature. 390: 518-21. PMID 9394002 DOI: 10.1038/37371 |
0.376 |
|
| 1997 |
Reggio PH, Wang T, Brown AE, Fleming DN, Seltzman HH, Griffin G, Pertwee RG, Compton DR, Abood ME, Martin BR. Importance of the C-1 substituent in classical cannabinoids to CB2 receptor selectivity: synthesis and characterization of a series of O,2-propano-delta 8-tetrahydrocannabinol analogs. Journal of Medicinal Chemistry. 40: 3312-8. PMID 9379452 DOI: 10.1021/Jm970136G |
0.374 |
|
| 1997 |
Seltzman HH, Fleming DN, Thomas BF, Gilliam AF, McCallion DS, Pertwee RG, Compton DR, Martin BR. Synthesis and pharmacological comparison of dimethylheptyl and pentyl analogs of anandamide. Journal of Medicinal Chemistry. 40: 3626-34. PMID 9357529 DOI: 10.1021/Jm9702950 |
0.392 |
|
| 1997 |
Ryan WJ, Banner WK, Wiley JL, Martin BR, Razdan RK. Potent anandamide analogs: the effect of changing the length and branching of the end pentyl chain. Journal of Medicinal Chemistry. 40: 3617-25. PMID 9357528 DOI: 10.1021/jm970212f |
0.497 |
|
| 1997 |
Dutta AK, Ryan W, Thomas BF, Singer M, Compton DR, Martin BR, Razdan RK. Synthesis, pharmacology, and molecular modeling of novel 4-alkyloxy indole derivatives related to cannabimimetic aminoalkyl indoles (AAIs). Bioorganic & Medicinal Chemistry. 5: 1591-600. PMID 9313864 DOI: 10.1016/S0968-0896(97)00111-9 |
0.391 |
|
| 1997 |
Meng Y, Lichtman AH, Bridgen DT, Martin BR. Inhalation studies with drugs of abuse. Nida Research Monograph. 173: 201-24. PMID 9260190 |
0.555 |
|
| 1997 |
Damaj MI, Patrick GS, Creasy KR, Martin BR. Pharmacology of lobeline, a nicotinic receptor ligand. The Journal of Pharmacology and Experimental Therapeutics. 282: 410-9. PMID 9223582 |
0.332 |
|
| 1997 |
Lake KD, Compton DR, Varga K, Martin BR, Kunos G. Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. 281: 1030-7. PMID 9190833 |
0.344 |
|
| 1997 |
Lichtman AH, Martin BR. The selective cannabinoid antagonist SR 141716A blocks cannabinoid-induced antinociception in rats. Pharmacology, Biochemistry, and Behavior. 57: 7-12. PMID 9164547 DOI: 10.1016/S0091-3057(96)00121-9 |
0.69 |
|
| 1997 |
Lake KD, Martin BR, Kunos G, Varga K. Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats. Hypertension. 29: 1204-10. PMID 9149688 DOI: 10.1161/01.Hyp.29.5.1204 |
0.323 |
|
| 1997 |
Huffman JW, Duncan SG, Wiley JL, Martin BR. Synthesis and pharmacology of the 1',2'-dimethylheptyl-Δ8-THC isomers: Exceptionally potent cannabinoids Bioorganic and Medicinal Chemistry Letters. 7: 2799-2804. DOI: 10.1016/S0960-894X(97)10086-5 |
0.528 |
|
| 1997 |
Ryan WJ, Banner WK, Crocker PJ, Martin BR, Razdan RK. Synthesis of (+)- and (-)-2-methylarachidonyl-2'-fluoroethylamide (O-689) Bioorganic & Medicinal Chemistry Letters. 7: 2669-2672. DOI: 10.1016/S0960-894X(97)10047-6 |
0.347 |
|
| 1997 |
Singer M, Dutta AK, Compton DR, Martin BR, Razdan RK. Synthesis and pharmacology of (R)- and (S)-4'-hydroxy-Δ9-tetrahydrocannabinols European Journal of Medicinal Chemistry. 32: 165-170. DOI: 10.1016/S0223-5234(97)87544-7 |
0.309 |
|
| 1997 |
Huffman JW, Lainton JAH, Banner WK, Duncan SG, Jordan RD, Yu S, Dai D, Martin BR, Wiley JL, Compton DR. Side chain methyl analogues of Δ8-THC Tetrahedron. 53: 1557-1576. DOI: 10.1016/S0040-4020(96)01134-9 |
0.524 |
|
| 1996 |
Wiley JL, Compton DR, Gordon PM, Siegel C, Singer M, Dutta A, Lichtman AH, Balster RL, Razdan RK, Martin BR. Evaluation of agonist-antagonist properties of nitrogen mustard and cyano derivatives of delta 8-tetrahydrocannabinol. Neuropharmacology. 35: 1793-804. PMID 9076759 DOI: 10.1016/S0028-3908(96)00120-7 |
0.775 |
|
| 1996 |
Pertwee RG, Fernando SR, Griffin G, Ryan W, Razdan RK, Compton DR, Martin BR. Agonist-antagonist characterization of 6'-cyanohex-2'-yne-delta 8-tetrahydrocannabinol in two isolated tissue preparations. European Journal of Pharmacology. 315: 195-201. PMID 8960884 DOI: 10.1016/S0014-2999(96)00631-0 |
0.372 |
|
| 1996 |
Meng Y, Lichtman AH, Bridgen DT, Martin BR. Pharmacological potency and biodisposition of phencyclidine via inhalation exposure in mice. Drug and Alcohol Dependence. 43: 13-22. PMID 8957139 DOI: 10.1016/S0376-8716(96)01284-7 |
0.797 |
|
| 1996 |
Abood ME, Martin BR. Molecular neurobiology of the cannabinoid receptor International Review of Neurobiology. 197-221. PMID 8894848 DOI: 10.1016/S0074-7742(08)60667-4 |
0.382 |
|
| 1996 |
Lichtman AH, Meng Y, Martin BR. Inhalation exposure to volatilized opioids produces antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 279: 69-76. PMID 8858977 |
0.649 |
|
| 1996 |
Lichtman AH, Martin BR. Delta 9-tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism. Psychopharmacology. 126: 125-31. PMID 8856831 DOI: 10.1007/Bf02246347 |
0.647 |
|
| 1996 |
Huffman JW, Yu S, Showalter V, Abood ME, Wiley JL, Compton DR, Martin BR, Bramblett RD, Reggio PH. Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor. Journal of Medicinal Chemistry. 39: 3875-7. PMID 8831752 DOI: 10.1021/Jm960394Y |
0.603 |
|
| 1996 |
Damaj MI, Martin BR. Tolerance to the antinociceptive effect of epibatidine after acute and chronic administration in mice. European Journal of Pharmacology. 300: 51-7. PMID 8741164 DOI: 10.1016/0014-2999(95)00834-9 |
0.398 |
|
| 1996 |
Fan F, Tao Q, Abood M, Martin BR. Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice Brain Research. 706: 13-20. PMID 8720487 DOI: 10.1016/0006-8993(95)01113-7 |
0.463 |
|
| 1996 |
Lichtman AH, Cook SA, Martin BR. Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement. The Journal of Pharmacology and Experimental Therapeutics. 276: 585-93. PMID 8632325 |
0.649 |
|
| 1996 |
Shivachar AC, Martin BR, Ellis EF. Anandamide- and delta9-tetrahydrocannabinol-evoked arachidonic acid mobilization and blockade by SR141716A [N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4 -methyl-1H-pyrazole-3-carboximide hydrochloride]. Biochemical Pharmacology. 51: 669-76. PMID 8615904 DOI: 10.1016/S0006-2952(95)02248-1 |
0.354 |
|
| 1996 |
Dukat M, Fiedler W, Dumas D, Damaj I, Martin BR, Rosecrans JA, James JR, Glennon RA. Pyrrolidine-modified and 6-substituted analogs of nicotine: A structure-affinity investigation European Journal of Medicinal Chemistry. 31: 875-888. DOI: 10.1016/S0223-5234(97)89850-9 |
0.364 |
|
| 1996 |
Imad Damaj M, Glassco W, Dukat M, May EL, Glennon RA, Martin BR. Pharmacology of novel nicotinic analogs Drug Development Research. 38: 177-187. DOI: 10.1002/(Sici)1098-2299(199607/08)38:3/4<177::Aid-Ddr6>3.0.Co;2-J |
0.375 |
|
| 1995 |
Wiley JL, Huffman JW, Balster RL, Martin BR. Pharmacological specificity of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rhesus monkeys. Drug and Alcohol Dependence. 40: 81-6. PMID 8746928 DOI: 10.1016/0376-8716(95)01193-5 |
0.589 |
|
| 1995 |
Damaj MI, Creasy KR, Welch SP, Rosecrans JA, Aceto MD, Martin BR. Comparative pharmacology of nicotine and ABT-418, a new nicotinic agonist. Psychopharmacology. 120: 483-90. PMID 8539331 DOI: 10.1007/Bf02245822 |
0.36 |
|
| 1995 |
Martin BR, Compton DR, Prescott WR, Barrett RL, Razdan RK. Pharmacological evaluation of dimethylheptyl analogs of delta 9-THC: reassessment of the putative three-point cannabinoid-receptor interaction. Drug and Alcohol Dependence. 37: 231-40. PMID 7796717 DOI: 10.1016/0376-8716(94)01081-U |
0.405 |
|
| 1995 |
Adams IB, Ryan W, Singer M, Thomas BF, Compton DR, Razdan RK, Martin BR. Evaluation of cannabinoid receptor binding and in vivo activities for anandamide analogs. The Journal of Pharmacology and Experimental Therapeutics. 273: 1172-81. PMID 7791088 |
0.302 |
|
| 1995 |
Wiley J, Balster R, Martin B. Discriminative stimulus effects of anandamide in rats. European Journal of Pharmacology. 276: 49-54. PMID 7781695 DOI: 10.1016/0014-2999(95)00010-I |
0.441 |
|
| 1995 |
Wenger T, Tóth BE, Martin BR. Effects of anandamide (endogen cannabinoid) on anterior pituitary hormone secretion in adult ovariectomized rats. Life Sciences. 56: 2057-63. PMID 7776832 DOI: 10.1016/0024-3205(95)00189-D |
0.301 |
|
| 1995 |
Cook SA, Welch SP, Lichtman AH, Martin BR. Evaluation of cAMP involvement in cannabinoid-induced antinociception. Life Sciences. 56: 2049-56. PMID 7776831 DOI: 10.1016/0024-3205(95)00188-C |
0.681 |
|
| 1995 |
Adams IB, Ryan W, Singer M, Razdan RK, Compton DR, Martin BR. Pharmacological and behavioral evaluation of alkylated anandamide analogs. Life Sciences. 56: 2041-8. PMID 7776830 DOI: 10.1016/0024-3205(95)00187-B |
0.377 |
|
| 1995 |
Ryan W, Singer M, Razdan RK, Compton DR, Martin BR. A novel class of potent tetrahydrocannabinols (THCS): 2'-yne-delta 8- and delta 9-THCS. Life Sciences. 56: 2013-20. PMID 7776826 DOI: 10.1016/0024-3205(95)00183-7 |
0.428 |
|
| 1995 |
Damaj MI, Welch SP, Martin BR. In vivo pharmacological effects of dihydro-β-erythroidine, a nicotinic antagonist, in mice Psychopharmacology. 117: 67-73. PMID 7724704 DOI: 10.1007/Bf02245100 |
0.37 |
|
| 1995 |
Lichtman AH, Dimen KR, Martin BR. Systemic or intrahippocampal cannabinoid administration impairs spatial memory in rats. Psychopharmacology. 119: 282-90. PMID 7675962 DOI: 10.1007/Bf02246292 |
0.648 |
|
| 1995 |
Glennon RA, Young R, Martin BR, Dal Cason TA. Methcathinone ("cat"): An enantiomeric potency comparison Pharmacology, Biochemistry and Behavior. 50: 601-606. PMID 7617707 DOI: 10.1016/0091-3057(94)00348-3 |
0.324 |
|
| 1995 |
Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR, Gopher A, Almog S, Martin BR, Compton DR. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochemical Pharmacology. 50: 83-90. PMID 7605349 DOI: 10.1016/0006-2952(95)00109-D |
0.377 |
|
| 1995 |
Varga K, Lake K, Martin BR, Kunos G. Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide. European Journal of Pharmacology. 278: 279-83. PMID 7589169 DOI: 10.1016/0014-2999(95)00181-J |
0.404 |
|
| 1995 |
Barrett RL, Wiley JL, Balster RL, Martin BR. Pharmacological specificity of delta 9-tetrahydrocannabinol discrimination in rats. Psychopharmacology. 118: 419-24. PMID 7568628 DOI: 10.1007/Bf02245942 |
0.605 |
|
| 1995 |
Wiley JL, Barrett RL, Lowe J, Balster RL, Martin BR. Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats. Neuropharmacology. 34: 669-76. PMID 7566504 DOI: 10.1016/0028-3908(95)00027-4 |
0.617 |
|
| 1995 |
Wiley JL, Lowe JA, Balster RL, Martin BR. Antagonism of the discriminative stimulus effects of delta 9-tetrahydrocannabinol in rats and rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 275: 1-6. PMID 7562536 |
0.588 |
|
| 1995 |
Lichtman AH, Sathe P, Dimen KR, Martin BR. Acute tolerance to the cardiovascular effects of volatilized cocaine free base in rats. Drug and Alcohol Dependence. 38: 247-54. PMID 7555625 DOI: 10.1016/0376-8716(95)01111-B |
0.594 |
|
| 1994 |
Damaj MI, Glennon RA, Martin BR. Involvement of the serotonergic system in the hypoactive and antinociceptive effects of nicotine in mice. Brain Research Bulletin. 33: 199-203. PMID 8275340 DOI: 10.1016/0361-9230(94)90252-6 |
0.377 |
|
| 1994 |
Martin BR, Welch SP, Abood M. Progress toward Understanding the Cannabinoid Receptor and Its Second Messenger Systems Advances in Pharmacology (San Diego). 25: 341-397. PMID 8204506 DOI: 10.1016/S1054-3589(08)60437-8 |
0.374 |
|
| 1994 |
Yan G, Yin D, Khanolkar AD, Compton DR, Martin BR, Makriyannis A. Synthesis and pharmacological properties of 11-hydroxy-3-(1',1'-dimethylheptyl)hexahydrocannabinol: a high-affinity cannabinoid agonist. Journal of Medicinal Chemistry. 37: 2619-22. PMID 8057304 DOI: 10.1021/Jm00042A015 |
0.335 |
|
| 1994 |
Damaj MI, Welch SP, Martin BR. Nicotine-induced antinociception in mice: Role of G-proteins and adenylate cyclase Pharmacology, Biochemistry and Behavior. 48: 37-42. PMID 8029303 DOI: 10.1016/0091-3057(94)90494-4 |
0.387 |
|
| 1994 |
McLaughlin CR, Martin BR, Compton DR, Abood ME. Cannabinoid receptors in developing rats: detection of mRNA and receptor binding. Drug and Alcohol Dependence. 36: 27-31. PMID 7988356 DOI: 10.1016/0376-8716(94)90006-X |
0.371 |
|
| 1994 |
Mechoulam R, Hanuš L, Martin BR. Search for endogenous ligands of the cannabinoid receptor. Biochemical Pharmacology. 48: 1537-1544. PMID 7980618 DOI: 10.1016/0006-2952(94)90197-X |
0.321 |
|
| 1994 |
May EL, Aceto MD, Bowman ER, Bentley C, Martin BR, Harris LS, Medzihradsky F, Mattson MV, Jacobson AE. Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties. Journal of Medicinal Chemistry. 37: 3408-18. PMID 7932569 DOI: 10.1021/Jm00046A026 |
0.606 |
|
| 1994 |
Damaj MI, Creasy KR, Grove AD, Rosecrans JA, Martin BR. Pharmacological effects of epibatidine optical enantiomers. Brain Research. 664: 34-40. PMID 7895043 DOI: 10.1016/0006-8993(94)91950-X |
0.387 |
|
| 1994 |
Huffman JW, Dai D, Martin BR, Compton DR. Design, Synthesis and Pharmacology of Cannabimimetic Indoles Bioorganic and Medicinal Chemistry Letters. 4: 563-566. DOI: 10.1016/S0960-894X(01)80155-4 |
0.355 |
|
| 1994 |
Lichtman AH, Martin BR. Changes in tail skin temperature are unlikely to be a confounding factor in the tail-flick test Pain. 57: 257-258. DOI: 10.1016/0304-3959(94)90235-6 |
0.572 |
|
| 1993 |
Wiley JL, Barrett RL, Balster RL, Martin BR. Tolerance to the discriminative stimulus effects of Delta(9)-tetrahydrocannabinol. Behavioural Pharmacology. 4: 581-585. PMID 11224227 |
0.534 |
|
| 1993 |
Wiley JL, Barrett RL, Britt DT, Balster RL, Martin BR. Discriminative stimulus effects of delta 9-tetrahydrocannabinol and delta 9-11-tetrahydrocannabinol in rats and rhesus monkeys. Neuropharmacology. 32: 359-65. PMID 8388551 DOI: 10.1016/0028-3908(93)90157-X |
0.594 |
|
| 1993 |
Lu R, Hubbard JR, Martin BR, Kalimi MY. Roles of sulfhydryl and disulfide groups in the binding of CP-55,940 to rat brain cannabinoid receptor. Molecular and Cellular Biochemistry. 121: 119-26. PMID 8316228 DOI: 10.1007/Bf00925970 |
0.368 |
|
| 1993 |
Abood ME, Sauss C, Fan F, Tilton CL, Martin BR. Development of behavioral tolerance to Δ9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain Pharmacology, Biochemistry and Behavior. 46: 575-579. PMID 8278434 DOI: 10.1016/0091-3057(93)90546-6 |
0.409 |
|
| 1993 |
Glassco W, Suchocki J, George C, Martin BR, May EL. Synthesis, optical resolution, absolute configuration, and preliminary pharmacology of (+)- and (-)-cis-2,3,3a,4,5,9b-hexahydro-1-methyl-1H- pyrrolo-[3,2-h]isoquinoline, a structural analog of nicotine. Journal of Medicinal Chemistry. 36: 3381-5. PMID 8230128 DOI: 10.1021/Jm00074A019 |
0.358 |
|
| 1993 |
Lichtman AH, Smith FL, Martin BR. Evidence that the antinociceptive tail-flick response is produced independently from changes in either tail-skin temperature or core temperature. Pain. 55: 283-95. PMID 8121689 DOI: 10.1016/0304-3959(93)90003-8 |
0.609 |
|
| 1993 |
Damaj MI, Martin BR. Is the dopaminergic system involved in the central effects of nicotine in mice Psychopharmacology. 111: 106-108. PMID 7870924 DOI: 10.1007/Bf02257415 |
0.366 |
|
| 1993 |
Damaj MI, Martin BR. Calcium agonists and antagonists of the dihydropyridine type: effect on nicotine-induced antinociception and hypomotility. Drug and Alcohol Dependence. 32: 73-9. PMID 7683598 DOI: 10.1016/0376-8716(93)90024-K |
0.336 |
|
| 1993 |
Wiley JL, Barrett RL, Balster RL, Martin BR. Tolerance to the discriminative stimulus effects of Δ9-tetrahydrocannabinol Behavioural Pharmacology. 4: 581-585. DOI: 10.1097/00008877-199312000-00004 |
0.521 |
|
| 1992 |
Darmani NA, Martin BR, Glennon RA. Repeated administration of low doses of cocaine enhances the sensitivity of 5-HT2 receptor function. Pharmacology, Biochemistry, and Behavior. 41: 519-27. PMID 1584831 DOI: 10.1016/0091-3057(92)90367-O |
0.33 |
|
| 1992 |
Lichtman AH, Smith PB, Martin BR. The antinociceptive effects of intrathecally administered cannabinoids are influenced by lipophilicity. Pain. 51: 19-26. PMID 1454400 DOI: 10.1016/0304-3959(92)90004-U |
0.681 |
|
| 1992 |
Darmani NA, Schnoll SH, Pandey U, Martin BR. Chronic prenatal methadone exposure alters central opioid μ-receptor affinity in both fetal and maternal brain Neurotoxicology and Teratology. 14: 265-271. PMID 1326078 DOI: 10.1016/0892-0362(92)90006-V |
0.372 |
|
| 1992 |
Smith PB, Martin BR. Spinal mechanisms ofΔ9-tetrahydrocannabinol-induced analgesia Brain Research. 578: 8-12. PMID 1324767 DOI: 10.1016/0006-8993(92)90222-U |
0.341 |
|
| 1992 |
Charalambous A, Yan G, Houston DB, Howlett AC, Compton DR, Martin BR, Makriyannis A. 5'-Azido-delta 8-THC: a novel photoaffinity label for the cannabinoid receptor. Journal of Medicinal Chemistry. 35: 3076-9. PMID 1323683 DOI: 10.1021/Jm00094A023 |
0.594 |
|
| 1992 |
Carroll FI, Abraham P, Parham K, Bai X, Zhang X, Brine GA, Mascarella SW, Martin BR, May EL, Sauss C. Enantiomeric N-substituted N-normetazocines: a comparative study of affinities at sigma, PCP, and mu opioid receptors. Journal of Medicinal Chemistry. 35: 2812-8. PMID 1322987 DOI: 10.1021/Jm00093A014 |
0.381 |
|
| 1992 |
Prescott WR, Gold LH, Martin BR. Evidence for separate neuronal mechanisms for the discriminative stimulus and catalepsy induced by delta 9-THC in the rat. Psychopharmacology. 107: 117-24. PMID 1317040 DOI: 10.1007/Bf02244975 |
0.373 |
|
| 1991 |
Darmani NA, Martin BR, Pandey U, Glennon RA. Pharmacological characterization of ear-scratch response in mice as a behavioral model for selective 5-HT2-receptor agonists and evidence for 5-HT1B- and 5-HT2-receptor interactions. Pharmacology, Biochemistry, and Behavior. 37: 95-9. PMID 2263671 DOI: 10.1016/0091-3057(90)90047-L |
0.364 |
|
| 1991 |
Glennon RA, Darmani NA, Martin BR. Multiple populations of serotonin receptors may modulate the behavioral effects of serotonergic agents. Life Sciences. 48: 2493-8. PMID 2046474 DOI: 10.1016/0024-3205(91)90603-9 |
0.318 |
|
| 1991 |
Suchocki JA, May EL, Martin TJ, George C, Martin BR. Synthesis of 2-exo- and 2-endo-mecamylamine analogues. Structure-activity relationships for nicotinic antagonism in the central nervous system. Journal of Medicinal Chemistry. 34: 1003-10. PMID 2002445 DOI: 10.1021/Jm00107A019 |
0.35 |
|
| 1991 |
Little PJ, Martin BR. The effects of Δ9-tetrahydrocannabinol and other cannabinoids on cAMP accumulation in synaptosomes Life Sciences. 48: 1133-1141. PMID 1848340 DOI: 10.1016/0024-3205(91)90450-P |
0.378 |
|
| 1991 |
Darmani NA, Martin BR, Pandey U, Glennon RA. Inhibition of 5-HT2 receptor-mediated head-twitch response by cocaine via indirect stimulation of adrenergic alpha 2 and serotonergic 5-HT1A receptors. Pharmacology, Biochemistry, and Behavior. 38: 353-7. PMID 1676173 DOI: 10.1016/0091-3057(91)90290-I |
0.345 |
|
| 1991 |
Lichtman AH, Martin BR. Cannabinoid-induced antinociception is mediated by a spinal alpha 2-noradrenergic mechanism. Brain Research. 559: 309-14. PMID 1665384 DOI: 10.1016/0006-8993(91)90017-P |
0.652 |
|
| 1991 |
Compton DR, Prescott WR, Martin BR, Siegel C, Gordon PM, Razdan RK. Synthesis and pharmacological evaluation of ether and related analogues of delta 8-, delta 9-, and delta 9,11-tetrahydrocannabinol. Journal of Medicinal Chemistry. 34: 3310-6. PMID 1659638 DOI: 10.1021/Jm00115A023 |
0.467 |
|
| 1991 |
Lichtman AH, Martin BR. Spinal and supraspinal components of cannabinoid-induced antinociception. The Journal of Pharmacology and Experimental Therapeutics. 258: 517-23. PMID 1650831 |
0.589 |
|
| 1991 |
Darmani NA, Schnoll SH, Fuchs B, Martin BR. Does chronic prenatal methadone exposure affect β-receptor subtypes in placental, fetal and maternal brain homogenates? Neurotoxicology and Teratology. 13: 43-48. PMID 1646380 DOI: 10.1016/0892-0362(91)90026-S |
0.312 |
|
| 1990 |
Compton DR, Martin BR. Pharmacological evaluation of water soluble cannabinoids and related analogs. Life Sciences. 46: 1575-85. PMID 2352451 DOI: 10.1016/0024-3205(90)90391-4 |
0.329 |
|
| 1990 |
Compton DR, Dewey WL, Martin BR. Cannabis dependence and tolerance production. Advances in Alcohol & Substance Abuse. 9: 129-47. PMID 2165734 DOI: 10.1300/J251V09N01_08 |
0.53 |
|
| 1990 |
Semus SF, Martin BR. A computergraphic investigation into the pharmacological role of the THC-cannabinoid phenolic moiety. Life Sciences. 46: 1781-1785. PMID 2163002 DOI: 10.1016/0024-3205(90)90142-E |
0.339 |
|
| 1990 |
Onaivi ES, Green MR, Martin BR. Pharmacological characterization of cannabinoids in the elevated plus maze. The Journal of Pharmacology and Experimental Therapeutics. 253: 1002-9. PMID 2162942 |
0.33 |
|
| 1990 |
Compton DR, Little PJ, Martin BR, Gilman JW, Saha JK, Jorapur VS, Sard HP, Razdan RK. Synthesis and pharmacological evaluation of amino, azido, and nitrogen mustard analogues of 10-substituted cannabidiol and 11- or 12-substituted delta 8-tetrahydrocannabinol. Journal of Medicinal Chemistry. 33: 1437-43. PMID 2158563 DOI: 10.1021/Jm00167A025 |
0.416 |
|
| 1990 |
Todd SL, Balster RL, Martin BR. Affinity of the enantiomers of α- and β-cyclazocine for binding to the phencyclidine and μ opioid receptors Life Sciences. 46: 895-901. PMID 2157122 DOI: 10.1016/0024-3205(90)90120-G |
0.347 |
|
| 1990 |
Darmani NA, Martin BR, Pandey U, Glennon RA. Do functional relationships exist between 5-HT1A and 5-HT2 receptors? Pharmacology, Biochemistry, and Behavior. 36: 901-6. PMID 2145593 DOI: 10.1016/0091-3057(90)90098-3 |
0.325 |
|
| 1990 |
Lichtman AH, Martin BR. Spinal action of cannabinoid-induced antinociception. Nida Research Monograph. 105: 422-4. PMID 1876060 |
0.568 |
|
| 1989 |
Glennon RA, Ismaiel AE, Martin B, Poff D, Sutton M. A preliminary behavioral investigation of PMMA, the 4-methoxy analog of methamphetamine. Pharmacology, Biochemistry, and Behavior. 31: 9-13. PMID 3252264 DOI: 10.1016/0091-3057(88)90303-6 |
0.386 |
|
| 1989 |
Onaivi ES, Todd S, Martin BR. Behavioral effects in the mouse during and following withdrawal from ethanol ingestion and/or nicotine administration Drug and Alcohol Dependence. 24: 205-211. PMID 2605996 DOI: 10.1016/0376-8716(89)90057-4 |
0.316 |
|
| 1989 |
Onaivi ES, Martin BR. Neuropharmacological and physiological validation of a computer-controlled two-compartment black and white box for the assessment of anxiety. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 13: 963-976. PMID 2573111 DOI: 10.1016/0278-5846(89)90047-X |
0.326 |
|
| 1989 |
Little PJ, Compton DR, Mechoulam R, Martin BR. Stereochemical effects of 11-OH-delta 8-THC-dimethylheptyl in mice and dogs. Pharmacology, Biochemistry, and Behavior. 32: 661-6. PMID 2544901 DOI: 10.1016/0091-3057(89)90014-2 |
0.408 |
|
| 1989 |
Compton DR, Little PJ, Martin BR, Saha JK, Gilman J, Sard H, Razdan RK. Synthesis and pharmacological evaluation of mercapto and thioacetyl analogues of cannabidiol and Δ8-tetrahydrocannabinol European Journal of Medicinal Chemistry. 24: 293-297. DOI: 10.1016/0223-5234(89)90012-3 |
0.352 |
|
| 1988 |
Lyddane JE, Thomas BF, Compton DR, Martin BR. Modification of phencyclidine intoxification and biodisposition by charcoal and other treatments. Pharmacology, Biochemistry, and Behavior. 30: 371-7. PMID 3174769 DOI: 10.1016/0091-3057(88)90470-4 |
0.306 |
|
| 1988 |
Scimeca JA, Martin BR. The Effect of Acute Dyflos (DFP) Treatment on [3H]Nicotine Binding to Mouse Brain Homogenate Journal of Pharmacy and Pharmacology. 40: 793-797. PMID 2907560 DOI: 10.1111/J.2042-7158.1988.Tb05174.X |
0.361 |
|
| 1987 |
Estrada U, Brase DA, Martin BR, Dewey WL. Cardiovascular effects of delta 9- and delta 9(11)-tetrahydrocannabinol and their interaction with epinephrine. Life Sciences. 41: 79-87. PMID 3037218 DOI: 10.1016/0024-3205(87)90559-5 |
0.553 |
|
| 1987 |
Beardsley PM, Scimeca JA, Martin BR. Studies on the agonistic activity of delta 9-11-tetrahydrocannabinol in mice, dogs and rhesus monkeys and its interactions with delta 9-tetrahydrocannabinol. The Journal of Pharmacology and Experimental Therapeutics. 241: 521-6. PMID 3033218 |
0.316 |
|
| 1986 |
Kachur JF, May EL, Awaya H, Egle JL, Aceto MD, Martin BR. Pharmacological effects of 1,2,3,5,6,10b-hexahydropyrido[2,3g]indolizine, a bridged-nicotine analog. Life Sciences. 38: 323-30. PMID 3945165 DOI: 10.1016/0024-3205(86)90079-2 |
0.332 |
|
| 1986 |
Aceto MD, Bagley RS, Dewey WL, Fu TC, Martin BR. The spinal cord as a major site for the antinociceptive action of nicotine in the rat. Neuropharmacology. 25: 1031-6. PMID 3774124 DOI: 10.1016/0028-3908(86)90198-X |
0.516 |
|
| 1985 |
Kachur JF, Rosemond R, Welch S, Bowman ER, Martin BR, Brase DA, Dewey WL. Comparison of the ability of opioid analgesics to increase endogenous opioid-like activity in the cerebrospinal fluid of rabbits. Life Sciences. 37: 2549-55. PMID 4079662 DOI: 10.1016/0024-3205(85)90613-7 |
0.546 |
|
| 1985 |
Reynolds ML, Little PJ, Thomas BF, Bagley RB, Martin BR. Relationship between the biodisposition of [3H]soman and its pharmacological effects in mice. Toxicology and Applied Pharmacology. 80: 409-20. PMID 4035696 DOI: 10.1016/0041-008X(85)90385-0 |
0.3 |
|
| 1985 |
Wessinger WD, Martin BR, Balster RL. Discriminative stimulus properties and brain distribution of phencyclidine in rats following administration by injection and smoke inhalation Pharmacology, Biochemistry and Behavior. 23: 607-612. PMID 2999833 DOI: 10.1016/0091-3057(85)90425-3 |
0.352 |
|
| 1985 |
Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 28: 783-7. PMID 2989518 DOI: 10.1021/Jm00383A016 |
0.67 |
|
| 1985 |
Martin BR. Structural requirements for cannabinoid-induced antinociceptive activity in mice Life Sciences. 36: 1523-1530. PMID 2984503 DOI: 10.1016/0024-3205(85)90376-5 |
0.357 |
|
| 1984 |
Freeman AS, Martin BR, Balster RL. Relationship between the development of behavioral tolerance and the biodisposition of phencyclidine in mice. Pharmacology, Biochemistry, and Behavior. 20: 373-7. PMID 6709671 DOI: 10.1016/0091-3057(84)90273-9 |
0.377 |
|
| 1984 |
Martin BR, Reynolds ML, Harris LS, Toro-Goyco E. Binding of [3H]phenycyclidine to rat and human blood constituents. Biochemical Pharmacology. 33: 429-34. PMID 6704162 DOI: 10.1016/0006-2952(84)90236-3 |
0.495 |
|
| 1984 |
Robertson LR, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Synthesis and pharmacological activity of some 9-substituted delta 8-tetrahydrocannabinol analogues. Journal of Medicinal Chemistry. 27: 550-2. PMID 6323713 DOI: 10.1021/Jm00370A023 |
0.652 |
|
| 1984 |
Shook JE, Kallman MJ, Martin BR, Dewey WL. Characterization of the interaction of pentazocine and tripelennamine: drug discrimination and mu-receptor binding assay. Pharmacology, Biochemistry, and Behavior. 21: 877-81. PMID 6097919 DOI: 10.1016/S0091-3057(84)80068-4 |
0.573 |
|
| 1984 |
Martin BR, Katzen JS, Woods JA, Tripathi HL, Harris LS, May EL. Stereoisomers of [3H]-N-allylnormetazocine bind to different sites in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 231: 539-44. PMID 6094791 |
0.454 |
|
| 1984 |
Martin BR, Kallman MJ, Kaempf GF, Harris LS, Dewey WL, Razdan RK. Pharmacological potency of R- and S-3'-hydroxy-delta 9-tetrahydrocannabinol: additional structural requirement for cannabinoid activity. Pharmacology, Biochemistry, and Behavior. 21: 61-5. PMID 6087379 DOI: 10.1016/0091-3057(84)90131-X |
0.648 |
|
| 1983 |
Rosin DL, Martin BR. Comparison of the effects of acute and subchronic administration of aroclor 1254, a commercial mixture of polychlorinated biphenyls, on pentobarbital‐induced sleep time and [14c]pentobarbital disposition in mice Journal of Toxicology and Environmental Health. 11: 917-931. PMID 6413697 DOI: 10.1080/15287398309530395 |
0.311 |
|
| 1983 |
Harris LS, Aceto MD, Balster RL, Martin BR. Progress report: Medical College of Virginia--sigma agonists. Nida Research Monograph. 43: 79-84. PMID 6308455 |
0.406 |
|
| 1983 |
Freeman AS, Martin BR. Interactions between phencyclidine and delta 9-tetrahydrocannabinol in mice following smoke exposure. Life Sciences. 32: 1081-9. PMID 6298542 DOI: 10.1016/0024-3205(83)90113-3 |
0.377 |
|
| 1983 |
Aceto MD, Awaya H, Martin BR, May EL. Antinociceptive action of nicotine and its methiodide derivatives in mice and rats. British Journal of Pharmacology. 79: 869-76. PMID 6140048 DOI: 10.1111/J.1476-5381.1983.Tb10531.X |
0.317 |
|
| 1983 |
Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. Pharmachology The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species Pain. 17: 393. DOI: 10.1016/0304-3959(83)90171-9 |
0.488 |
|
| 1982 |
Dewey WL, Bowman E, Jones D, Kachur J, Rosemond R, Welch S, Martin BR. The appearance of endogenous opiates in cerebrospinal fluid following opiate injection in various animal species. Life Sciences. 31: 1741-3. PMID 7154834 DOI: 10.1016/0024-3205(82)90199-0 |
0.554 |
|
| 1982 |
Handrick GR, Duffley RP, Lambert G, Murphy JG, Dalzell HC, Howes JF, Razdan RK, Martin BR, Harris LS, Dewey WL. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 25: 1447-50. PMID 6296389 |
0.629 |
|
| 1982 |
Dewey WL, Fu TC, Ohlsson A, Bowman E, Martin BR. Evidence for the release of endogenous opiates by morphine. Nida Research Monograph. 41: 60-6. PMID 6289120 |
0.422 |
|
| 1982 |
Ohlsson AE, Fu TC, Jones D, Martin BR, Dewey WL. Distribution of radioactivity in the spinal cord after intracerebroventricular and intravenous injection of radiolabeled opioid peptides in mice. The Journal of Pharmacology and Experimental Therapeutics. 221: 362-7. PMID 6281413 |
0.45 |
|
| 1981 |
Vincek WC, Martin BR, Aceto MD, Tripathi HL, May EL, Harris LS. Synthesis of 4,4-ditritio-(+)-nicotine: comparative binding and distribution studies with natural enantiomer. Journal of Pharmaceutical Sciences. 70: 1292-3. PMID 7299682 DOI: 10.1002/JPS.2600701131 |
0.523 |
|
| 1981 |
Martin BR, Aceto MD. Nicotine binding sites and their localization in the central nervous system Neuroscience & Biobehavioral Reviews. 5: 473-478. PMID 7033844 DOI: 10.1016/0149-7634(81)90017-8 |
0.303 |
|
| 1981 |
Martin BR, Balster RL, Razdan RK, Harris LS, Dewey WL. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sciences. 29: 565-74. PMID 6268916 DOI: 10.1016/0024-3205(81)90434-3 |
0.632 |
|
| 1980 |
Vincek WC, Martin BR, Aceto MD, Bowman ER. Synthesis and preliminary binding studies of 4,4-ditritio-(-)-nicotine of high specific activity. Journal of Medicinal Chemistry. 23: 960-962. PMID 7401120 DOI: 10.1021/Jm00182A028 |
0.304 |
|
| 1980 |
Woolverton WL, Martin BR, Balster RL. Modification of the behavioral effects of phencyclidine by repeated drug exposure and body weight changes. Pharmacology, Biochemistry, and Behavior. 12: 761-6. PMID 7393970 DOI: 10.1016/0091-3057(80)90163-X |
0.309 |
|
| 1980 |
Man M, Harris LS, Woods LA, Martin BR. Isotope dilution technique for the estimation of l-alpha-[2-3H]-acetylmethadol and its metabolites in biological samples. Pharmacology. 20: 130-6. PMID 6992151 |
0.391 |
|
| 1980 |
Alozie SO, Martin BR, Harris LS, Dewey WL. 3H-delta 9-Tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: penetration and regional distribution in rat brain. Pharmacology, Biochemistry, and Behavior. 12: 217-21. PMID 6246544 DOI: 10.1016/0091-3057(80)90359-7 |
0.612 |
|
| 1980 |
Man M, Alozie SO, Woods LA, Martin BR, Harris LS. Distribution of l-alpha-[2-3H]acetylmethadol and its metabolites in maternal and fetal rat tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 8: 55-9. PMID 6103787 |
0.391 |
|
| 1979 |
Wilson RS, Martin BR, Dewey WL. Some 11-substituted tetrahydrocannabinols. Synthesis and comparison with the potent cannabinoid metabolites 11-hydroxytetrahydrocannabinols. Journal of Medicinal Chemistry. 22: 879-82. PMID 448686 DOI: 10.1021/JM00193A025 |
0.557 |
|
| 1979 |
Aceto MD, Martin BR, Uwaydah IM, May EL, Harris LS, Izazola-Conde C, Dewey WL, Bradshaw TJ, Vincek WC. Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine. Journal of Medicinal Chemistry. 22: 174-7. PMID 423195 DOI: 10.1021/JM00188A009 |
0.624 |
|
| 1979 |
Carney JM, Balster RL, Martin BR, Harris LS. Effects of systemic and intraventricular administration of cannabinoids on schedule-controlled responding in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 210: 399-404. PMID 113528 |
0.492 |
|
| 1979 |
Toro-Goyco E, Martin BR, Harris LS. The binding of LAAM and its metabolites to blood constituents. Nida Research Monograph. 27: 54-60. PMID 95037 |
0.393 |
|
| 1978 |
Harris LS, Carchman RA, Martin BR. Evidence for the existence of specific cannabinoid binding sites. Life Sciences. 22: 1131-7. PMID 661500 DOI: 10.1016/0024-3205(78)90082-6 |
0.49 |
|
| 1978 |
Martin BR, Montgomery J, Dewey WL, Harris LS. Alterations in the pharmacokinetics of 3H-delta9-tetrahydrocannabinol in mice by bacterial endotoxin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 282-7. PMID 26549 |
0.625 |
|
| 1977 |
Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Research Communications in Chemical Pathology and Pharmacology. 17: 457-70. PMID 897339 |
0.564 |
|
| 1977 |
Adams MD, Earnhardt JT, Martin BR, Harris LS, Dewey WL, Razdan RK. A cannabinoid with cardiovascular activity but no overt behavioral effects. Experientia. 33: 1204-5. PMID 891878 DOI: 10.1007/Bf01922330 |
0.634 |
|
| 1977 |
Martin BR, Dewey WL, Aceto MD, Adams MD, Earnhardt JT, Carney JM. A potent antinociceptive cannabinoid which lacks opiate substitution properties in monkeys. Research Communications in Chemical Pathology and Pharmacology. 16: 187-90. PMID 402685 |
0.472 |
|
| 1977 |
Martin BR, Dewey WL, Chau-Pham T, Prnage AJ. Interactions of thyrotropin releasing hormone and morphine sulfate in rodents. Life Sciences. 20: 715-22. PMID 402526 DOI: 10.1016/0024-3205(77)90477-5 |
0.539 |
|
| 1976 |
Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol tissue and subcellular distribution in the central nervous system and tissue distribution in peripheral organs of tolerant and nontolerant dogs. The Journal of Pharmacology and Experimental Therapeutics. 196: 128-44. PMID 1246007 |
0.575 |
|
| 1976 |
Wilson RS, May EL, Martin BR, Dewey WL. 9 Nor 9 hydroxyhexahydrocannabinols. Synthesis, some behavioral and analgesic properties, and comparison with the tetrahydrocannabinols Journal of Medicinal Chemistry. 19: 1165-1167. PMID 978681 DOI: 10.1002/Chin.197652236 |
0.538 |
|
| 1975 |
Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacology, Biochemistry, and Behavior. 3: 849-53. PMID 1208625 DOI: 10.1016/0091-3057(75)90116-1 |
0.672 |
|
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