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Nobuyo Maeda - Publications

Affiliations: 
Genetics & Molecular Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Genetics, Pathology, Physiology Biology
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294 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Chang CS, Yu SS, Ho LC, Chao SH, Chou TY, Shao AN, Kao LZ, Chang CY, Chen YH, Wu MS, Tsai PJ, Maeda N, Tsai YS. Inguinal Fat Compensates Whole Body Metabolic Functionality in Partially Lipodystrophic Mice with Reduced PPARγ Expression. International Journal of Molecular Sciences. 24. PMID 36835312 DOI: 10.3390/ijms24043904  0.672
2020 Tian S, Nakamura J, Hiller S, Simington S, Holley DW, Mota R, Willis MS, Bultman SJ, Luft JC, DeSimone JM, Jia Z, Maeda N, Yi X. New insights into immunomodulation via overexpressing lipoic acid synthase as a therapeutic potential to reduce atherosclerosis. Vascular Pharmacology. 106777. PMID 32750408 DOI: 10.1016/J.Vph.2020.106777  0.444
2020 Banerjee S, Andrew RJ, Duff CJ, Fisher K, Jackson CD, Lawrence CB, Maeda N, Greenspan DS, Kellett KAB, Hooper NM. Author Correction: Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake. Scientific Reports. 10: 2681. PMID 32042031 DOI: 10.1038/S41598-020-59765-Y  0.301
2019 Banerjee S, Andrew RJ, Duff CJ, Fisher K, Jackson CD, Lawrence CB, Maeda N, Greenspan DS, Kellett KAB, Hooper NM. Proteolysis of the low density lipoprotein receptor by bone morphogenetic protein-1 regulates cellular cholesterol uptake. Scientific Reports. 9: 11416. PMID 31388055 DOI: 10.1038/S41598-019-47814-0  0.413
2019 Terajima M, Taga Y, Cabral WA, Liu Y, Nagasawa M, Sumida N, Kayashima Y, Chandrasekaran P, Han L, Maeda N, Perdivara I, Hattori S, Marini JC, Yamauchi M. Cyclophilin B control of lysine post-translational modifications of skin type I collagen. Plos Genetics. 15: e1008196. PMID 31173582 DOI: 10.1371/Journal.Pgen.1008196  0.357
2018 Govindapillai A, Hotchkiss A, Baguma-Nibasheka M, Rose RA, Miquerol L, Smithies O, Maeda N, Pasumarthi KBS. Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system. Scientific Reports. 8: 6939. PMID 29720615 DOI: 10.1038/S41598-018-25292-0  0.524
2017 Engstrom AK, Snyder JM, Maeda N, Xia Z. Correction to: Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Molecular Neurodegeneration. 12: 81. PMID 29100536 DOI: 10.1186/S13024-017-0223-7  0.358
2017 Makhanova N, Morgan AP, Kayashima Y, Makhanov A, Hiller S, Zhilicheva S, Xu L, Pardo-Manuel de Villena F, Maeda N. Genetic architecture of atherosclerosis dissected by QTL analyses in three F2 intercrosses of apolipoprotein E-null mice on C57BL6/J, DBA/2J and 129S6/SvEvTac backgrounds. Plos One. 12: e0182882. PMID 28837567 DOI: 10.1371/Journal.Pone.0182882  0.367
2017 Kayashima Y, Makhanova N, Maeda N. DBA/2J Haplotype on Distal Chromosome 2 Reduces Mertk Expression, Restricts Efferocytosis, and Increases Susceptibility to Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28473436 DOI: 10.1161/Atvbaha.117.309522  0.369
2016 Li F, Fushima T, Oyanagi G, Townley-Tilson HW, Sato E, Nakada H, Oe Y, Hagaman JR, Wilder J, Li M, Sekimoto A, Saigusa D, Sato H, Ito S, Jennette JC, ... Maeda N, et al. Nicotinamide benefits both mothers and pups in two contrasting mouse models of preeclampsia. Proceedings of the National Academy of Sciences of the United States of America. PMID 27821757 DOI: 10.1073/Pnas.1614947113  0.51
2016 Xu L, Hiller S, Simington S, Nickeleit V, Maeda N, James LR, Yi X. Influence of Different Levels of Lipoic Acid Synthase Gene Expression on Diabetic Nephropathy. Plos One. 11: e0163208. PMID 27706190 DOI: 10.1371/Journal.Pone.0163208  0.401
2016 Liu YH, Tsai YS, Lin SC, Liao NS, Jan MS, Liang CT, Hsu SW, Chen WC, Sung JM, Maeda N, Tsai PJ. Quantitative PPARγ expression affects the balance between tolerance and immunity. Scientific Reports. 6: 26646. PMID 27221351 DOI: 10.1038/Srep26646  0.663
2016 Arbones-Mainar JM, Johnson LA, Torres-Perez E, Garcia AE, Perez-Diaz S, Raber J, Maeda N. Metabolic shifts towards fatty acid usage and increased thermogenesis are associated with impaired adipogenesis in mice expressing human APOE4. International Journal of Obesity (2005). PMID 27163745 DOI: 10.1038/Ijo.2016.93  0.736
2016 Tai HC, Tsai PJ, Chen JY, Lai CH, Wang KC, Teng SH, Lin SC, Chang AY, Jiang MJ, Li YH, Wu HL, Maeda N, Tsai YS. Peroxisome Proliferator-Activated Receptor γ Level Contributes to Structural Integrity and Component Production of Elastic Fibers in the Aorta. Hypertension. PMID 27045031 DOI: 10.1161/Hypertensionaha.116.07367  0.678
2015 Moore SM, Zhang H, Maeda N, Doerschuk CM, Faber JE. Cardiovascular risk factors cause premature rarefaction of the collateral circulation and greater ischemic tissue injury. Angiogenesis. 18: 265-81. PMID 25862671 DOI: 10.1007/S10456-015-9465-6  0.333
2015 Kayashima Y, Makhanova NA, Matsuki K, Tomita H, Bennett BJ, Maeda N. Identification of aortic arch-specific quantitative trait loci for atherosclerosis by an intercross of DBA/2J and 129S6 apolipoprotein E-deficient mice. Plos One. 10: e0117478. PMID 25689165 DOI: 10.1371/Journal.Pone.0117478  0.435
2015 Huang ZH, Reardon CA, Getz GS, Maeda N, Mazzone T. Selective suppression of adipose tissue apoE expression impacts systemic metabolic phenotype and adipose tissue inflammation. Journal of Lipid Research. 56: 215-26. PMID 25421060 DOI: 10.1194/Jlr.M050567  0.41
2015 Kayashima Y, Makhanova NA, Matsuki K, Tomita H, Bennett BJ, Maeda N. Identification of aortic arch-specific quantitative trait loci for atherosclerosis by an intercross of DBA/2J and 129S6 apolipoprotein E-deficient mice Plos One. 10. DOI: 10.1371/journal.pone.0117478  0.302
2014 Smithies O, Lawrence M, Testen A, Horne LP, Wilder J, Altenburg M, Bleasdale B, Maeda N, Koklic T. Stable oligomeric clusters of gold nanoparticles: preparation, size distribution, derivatization, and physical and biological properties. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 13394-404. PMID 25317930 DOI: 10.1021/La5032637  0.764
2014 Perez-Diaz S, Johnson LA, DeKroon RM, Moreno-Navarrete JM, Alzate O, Fernandez-Real JM, Maeda N, Arbones-Mainar JM. Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3769-79. PMID 24812087 DOI: 10.1096/Fj.14-251165  0.695
2014 Hanaoka Y, Yasuda O, Soejima H, Miyata K, Yamamoto E, Izumiya Y, Maeda N, Ohishi M, Rakugi H, Oike Y, Kim-Mitsuyama S, Ogawa H. Tissue inhibitor of metalloproteinase-3 knockout mice exhibit enhanced energy expenditure through thermogenesis. Plos One. 9: e94930. PMID 24736588 DOI: 10.1371/Journal.Pone.0094930  0.448
2014 Hiller S, DeKroon R, Xu L, Robinette J, Winnik W, Alzate O, Simington S, Maeda N, Yi X. α-Lipoic acid protects mitochondrial enzymes and attenuates lipopolysaccharide-induced hypothermia in mice. Free Radical Biology & Medicine. 71: 362-7. PMID 24675228 DOI: 10.1016/J.Freeradbiomed.2014.03.022  0.345
2014 Kayashima Y, Tomita H, Zhilicheva S, Kim S, Kim HS, Bennett BJ, Maeda N. Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice Plos One. 9. PMID 24586312 DOI: 10.1371/Journal.Pone.0088274  0.402
2014 Vellaichamy E, Das S, Subramanian U, Maeda N, Pandey KN. Genetically altered mutant mouse models of guanylyl cyclase/natriuretic peptide receptor-A exhibit the cardiac expression of proinflammatory mediators in a gene-dose-dependent manner. Endocrinology. 155: 1045-56. PMID 24424043 DOI: 10.1210/En.2013-1416  0.47
2014 Johnson LA, Olsen RH, Merkens LS, DeBarber A, Steiner RD, Sullivan PM, Maeda N, Raber J. Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner. Neurobiology of Disease. 64: 150-62. PMID 24412220 DOI: 10.1016/J.Nbd.2013.12.016  0.74
2014 Chang CS, Tsai PJ, Sung JM, Chen JY, Ho LC, Pandya K, Maeda N, Tsai YS. Diuretics prevent thiazolidinedione-induced cardiac hypertrophy without compromising insulin-sensitizing effects in mice. The American Journal of Pathology. 184: 442-53. PMID 24287404 DOI: 10.1016/J.Ajpath.2013.10.020  0.688
2013 James LR, Le C, Doherty H, Kim HS, Maeda N. Connective tissue growth factor (CTGF) expression modulates response to high glucose. Plos One. 8: e70441. PMID 23950936 DOI: 10.1371/Journal.Pone.0070441  0.814
2013 Wait JM, Tomita H, Burk LM, Lu J, Zhou OZ, Maeda N, Lee YZ. Detection of aortic arch calcification in apolipoprotein E-null mice using carbon nanotube-based micro-CT system. Journal of the American Heart Association. 2: e003358. PMID 23525427 DOI: 10.1161/Jaha.112.003358  0.389
2013 Johnson LA, Kim HS, Knudson MJ, Nipp CT, Yi X, Maeda N. Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation. Journal of Lipid Research. 54: 386-96. PMID 23204275 DOI: 10.1194/Jlr.M031435  0.718
2013 Wölkart G, Beretta M, Wenzl MV, Stessel H, Schmidt K, Maeda N, Mayer B, Schrammel A. Tolerance to nitroglycerin through proteasomal down-regulation of aldehyde dehydrogenase-2 in a genetic mouse model of ascorbate deficiency. British Journal of Pharmacology. 168: 1868-77. PMID 23194305 DOI: 10.1111/Bph.12081  0.444
2012 Yi X, Xu L, Hiller S, Kim HS, Maeda N. Reduced alpha-lipoic acid synthase gene expression exacerbates atherosclerosis in diabetic apolipoprotein E-deficient mice. Atherosclerosis. 223: 137-43. PMID 22658261 DOI: 10.1016/J.Atherosclerosis.2012.04.025  0.464
2012 Pendse AA, Johnson LA, Kim HS, McNair M, Nipp CT, Wilhelm C, Maeda N. Pro- and antiatherogenic effects of a dominant-negative P465L mutation of peroxisome proliferator-activated receptor-γ in apolipoprotein E-Null mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1436-44. PMID 22539598 DOI: 10.1161/Atvbaha.112.248682  0.84
2012 Fox RG, Magness S, Kujoth GC, Prolla TA, Maeda N. Mitochondrial DNA polymerase editing mutation, PolgD257A, disturbs stem-progenitor cell cycling in the small intestine and restricts excess fat absorption. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G914-24. PMID 22345551 DOI: 10.1152/Ajpgi.00402.2011  0.764
2012 Li F, Hagaman JR, Kim HS, Maeda N, Jennette JC, Faber JE, Karumanchi SA, Smithies O, Takahashi N. eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. Journal of the American Society of Nephrology : Jasn. 23: 652-60. PMID 22282588 DOI: 10.1681/Asn.2011040369  0.633
2012 Tomita H, Hagaman J, Friedman MH, Maeda N. Relationship between hemodynamics and atherosclerosis in aortic arches of apolipoprotein E-null mice on 129S6/SvEvTac and C57BL/6J genetic backgrounds. Atherosclerosis. 220: 78-85. PMID 22078246 DOI: 10.1016/J.Atherosclerosis.2011.10.020  0.421
2012 Yi X, Xu L, Hiller S, Kim HS, Nickeleit V, James LR, Maeda N. Reduced expression of lipoic acid synthase accelerates diabetic nephropathy Journal of the American Society of Nephrology. 23: 103-111. PMID 22021711 DOI: 10.1681/Asn.2011010003  0.333
2012 Schrammel A, Wölkart G, Beretta M, Stessel H, Schmidt K, Maeda N, Mayer B. Tolerance to nitroglycerin through proteasomal degradation of aldehyde dehydrogenase-2 in a genetic mouse model of ascorbate deficiency Bmc Pharmacology and Toxicology. 13. DOI: 10.1186/2050-6511-13-S1-A36  0.308
2011 Chung S, Sawyer JK, Gebre AK, Maeda N, Parks JS. Adipose tissue ATP binding cassette transporter A1 contributes to high-density lipoprotein biogenesis in vivo. Circulation. 124: 1663-72. PMID 21931081 DOI: 10.1161/Circulationaha.111.025445  0.474
2011 Raife TJ, Dwyre DM, Stevens JW, Erger RA, Leo L, Wilson KM, Fernández JA, Wilder J, Kim HS, Griffin JH, Maeda N, Lentz SR. Human thrombomodulin knock-in mice reveal differential effects of human thrombomodulin on thrombosis and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2509-17. PMID 21885846 DOI: 10.1161/Atvbaha.111.236828  0.502
2011 Maeda N. Development of apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1957-62. PMID 21849705 DOI: 10.1161/Atvbaha.110.220574  0.404
2011 Johnson LA, Arbones-Mainar JM, Fox RG, Pendse AA, Altenburg MK, Kim HS, Maeda N. Apolipoprotein E4 exaggerates diabetic dyslipidemia and atherosclerosis in mice lacking the LDL receptor. Diabetes. 60: 2285-94. PMID 21810592 DOI: 10.2337/Db11-0466  0.806
2011 Huang ZH, Maeda N, Mazzone T. Expression of the human apoE2 isoform in adipocytes: altered cellular processing and impaired adipocyte lipogenesis. Journal of Lipid Research. 52: 1733-41. PMID 21743035 DOI: 10.1194/Jlr.M017160  0.502
2011 Fox R, Kim HS, Reddick RL, Kujoth GC, Prolla TA, Tsutsumi S, Wada Y, Smithies O, Maeda N. Mitochondrial DNA polymerase editing mutation, PolgD257A, reduces the diabetic phenotype of Akita male mice by suppressing appetite. Proceedings of the National Academy of Sciences of the United States of America. 108: 8779-84. PMID 21555558 DOI: 10.1073/Pnas.1106344108  0.798
2011 Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N. A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Proceedings of the National Academy of Sciences of the United States of America. 108: 2070-5. PMID 21245338 DOI: 10.1073/Pnas.1018766108  0.568
2011 Yi X, Nickeleit V, James LR, Maeda N. α-Lipoic acid protects diabetic apolipoprotein E-deficient mice from nephropathy Journal of Diabetes and Its Complications. 25: 193-201. PMID 20801062 DOI: 10.1016/J.Jdiacomp.2010.07.004  0.405
2011 Wang CH, Li F, Hiller S, Kim HS, Maeda N, Smithies O, Takahashi N. A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 5, (2070-2075) DOI:10.1073/pnas.1018766108) Proceedings of the National Academy of Sciences of the United States of America. 108: 3453. DOI: 10.1073/Pnas.1101346108  0.555
2010 Johnson LA, Maeda N. Macrovascular complications of diabetes in atherosclerosisprone mice. Expert Review of Endocrinology & Metabolism. 5: 89-98. PMID 30934383 DOI: 10.1586/Eem.09.66  0.629
2010 Doherty HE, Kim HS, Hiller S, Sulik KK, Maeda N. A mouse strain where basal connective tissue growth factor gene expression can be switched from low to high. Plos One. 5: e12909. PMID 20877562 DOI: 10.1371/Journal.Pone.0012909  0.817
2010 Pendse AA, Johnson LA, Tsai YS, Maeda N. Pparg-P465L mutation worsens hyperglycemia in Ins2-Akita female mice via adipose-specific insulin resistance and storage dysfunction. Diabetes. 59: 2890-7. PMID 20724579 DOI: 10.2337/Db10-0673  0.795
2010 Kandalam V, Basu R, Abraham T, Wang X, Awad A, Wang W, Lopaschuk GD, Maeda N, Oudit GY, Kassiri Z. Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1012-23. PMID 20675565 DOI: 10.1152/Ajpheart.00246.2010  0.316
2010 Li F, Wang CH, Wang JG, Thai T, Boysen G, Xu L, Turner AL, Wolberg AS, Mackman N, Maeda N, Takahashi N. Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet. Journal of Thrombosis and Haemostasis : Jth. 8: 2122-32. PMID 20626618 DOI: 10.1111/J.1538-7836.2010.03976.X  0.379
2010 Arbones-Mainar JM, Johnson LA, Altenburg MK, Kim HS, Maeda N. Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3809-18. PMID 20501792 DOI: 10.1096/Fj.10-159517  0.835
2010 Yi X, Xu L, Kim K, Kim HS, Maeda N. Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice. Atherosclerosis. 211: 424-30. PMID 20347443 DOI: 10.1016/J.Atherosclerosis.2010.03.009  0.445
2010 Chung S, Timmins JM, Duong M, Degirolamo C, Rong S, Sawyer JK, Singaraja RR, Hayden MR, Maeda N, Rudel LL, Shelness GS, Parks JS. Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism. The Journal of Biological Chemistry. 285: 12197-209. PMID 20178985 DOI: 10.1074/Jbc.M109.096933  0.438
2010 Tomita H, Zhilicheva S, Kim S, Maeda N. Aortic arch curvature and atherosclerosis have overlapping quantitative trait loci in a cross between 129S6/SvEvTac and C57BL/6J apolipoprotein E-null mice. Circulation Research. 106: 1052-60. PMID 20133902 DOI: 10.1161/Circresaha.109.207175  0.407
2010 Keen HL, Halabi CM, Beyer AM, de Lange WJ, Liu X, Maeda N, Faraci FM, Casavant TL, Sigmund CD. Bioinformatic analysis of gene sets regulated by ligand-activated and dominant-negative peroxisome proliferator-activated receptor gamma in mouse aorta. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 518-25. PMID 20018933 DOI: 10.1161/Atvbaha.109.200733  0.408
2009 Zhu H, Zhang J, Shih J, Lopez-Bertoni F, Hagaman JR, Maeda N, Friedman MH. Differences in aortic arch geometry, hemodynamics, and plaque patterns between C57BL/6 and 129/SvEv mice. Journal of Biomechanical Engineering. 131: 121005. PMID 20524728 DOI: 10.1115/1.4000168  0.333
2009 Tsai YS, Xu L, Smithies O, Maeda N. Genetic variations in peroxisome proliferator-activated receptor gamma expression affect blood pressure. Proceedings of the National Academy of Sciences of the United States of America. 106: 19084-9. PMID 19884495 DOI: 10.1073/Pnas.0909657106  0.751
2009 Baba Y, Yasuda O, Takemura Y, Ishikawa Y, Ohishi M, Iwanami J, Mogi M, Doe N, Horiuchi M, Maeda N, Fukuo K, Rakugi H. Timp-3 deficiency impairs cognitive function in mice. Laboratory Investigation; a Journal of Technical Methods and Pathology. 89: 1340-7. PMID 19806081 DOI: 10.1038/Labinvest.2009.101  0.37
2009 Scott NJ, Ellmers LJ, Lainchbury JG, Maeda N, Smithies O, Richards AM, Cameron VA. Influence of natriuretic peptide receptor-1 on survival and cardiac hypertrophy during development. Biochimica Et Biophysica Acta. 1792: 1175-84. PMID 19782130 DOI: 10.1016/J.Bbadis.2009.09.009  0.551
2009 Tsai YS, Tsai PJ, Jiang MJ, Chou TY, Pendse A, Kim HS, Maeda N. Decreased PPAR gamma expression compromises perigonadal-specific fat deposition and insulin sensitivity. Molecular Endocrinology (Baltimore, Md.). 23: 1787-98. PMID 19749155 DOI: 10.1210/Me.2009-0073  0.812
2009 Kassiri Z, Oudit GY, Kandalam V, Awad A, Wang X, Ziou X, Maeda N, Herzenberg AM, Scholey JW. Loss of TIMP3 enhances interstitial nephritis and fibrosis. Journal of the American Society of Nephrology : Jasn. 20: 1223-35. PMID 19406980 DOI: 10.1681/Asn.2008050492  0.346
2009 Nishikimi T, Inaba-Iemura C, Ishimura K, Tadokoro K, Koshikawa S, Ishikawa K, Akimoto K, Hattori Y, Kasai K, Minamino N, Maeda N, Matsuoka H. Natriuretic peptide/natriuretic peptide receptor-A (NPR-A) system has inhibitory effects in renal fibrosis in mice. Regulatory Peptides. 154: 44-53. PMID 19223006 DOI: 10.1016/J.Regpep.2009.02.006  0.401
2009 Wu JS, Cheung WM, Tsai YS, Chen YT, Fong WH, Tsai HD, Chen YC, Liou JY, Shyue SK, Chen JJ, Chen YE, Maeda N, Wu KK, Lin TN. Ligand-activated peroxisome proliferator-activated receptor-gamma protects against ischemic cerebral infarction and neuronal apoptosis by 14-3-3 epsilon upregulation. Circulation. 119: 1124-34. PMID 19221220 DOI: 10.1161/Circulationaha.108.812537  0.622
2009 Meredith D, Panchatcharam M, Miriyala S, Tsai YS, Morris AJ, Maeda N, Stouffer GA, Smyth SS. Dominant-negative loss of PPARgamma function enhances smooth muscle cell proliferation, migration, and vascular remodeling. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 465-71. PMID 19179641 DOI: 10.1161/Atvbaha.109.184234  0.673
2009 Svasti S, Suwanmanee T, Fucharoen S, Moulton HM, Nelson MH, Maeda N, Smithies O, Kole R. RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 1205-10. PMID 19164558 DOI: 10.1073/Pnas.0812436106  0.676
2009 Franceschini N, Muallem H, Rose KM, Boerwinkle E, Maeda N. Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study. Journal of Thrombosis and Haemostasis : Jth. 7: 496-8. PMID 19087220 DOI: 10.1111/J.1538-7836.2008.03262.X  0.343
2009 Pendse AA, Arbones-Mainar JM, Johnson LA, Altenburg MK, Maeda N. Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond. Journal of Lipid Research. 50: S178-82. PMID 19060252 DOI: 10.1194/Jlr.R800070-Jlr200  0.831
2009 Yi X, Kim K, Yuan W, Xu L, Kim HS, Homeister JW, Key NS, Maeda N. Mice with heterozygous deficiency of lipoic acid synthase have an increased sensitivity to lipopolysaccharide-induced tissue injury. Journal of Leukocyte Biology. 85: 146-53. PMID 18845616 DOI: 10.1189/Jlb.0308161  0.449
2009 Tsai Y, Tsai P, Jiang M, Chou T, Pendse A, Kim H, Maeda N. Decreased PPARγ Expression Compromises Perigonadal-Specific Fat Deposition and Insulin Sensitivity The Journal of Clinical Endocrinology & Metabolism. 94: 4118-4118. DOI: 10.1210/Jcem.94.10.9994  0.774
2008 Pandya K, Cowhig J, Brackhan J, Kim HS, Hagaman J, Rojas M, Carter CW, Mao L, Rockman HA, Maeda N, Smithies O. Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 13063-8. PMID 18755891 DOI: 10.1073/Pnas.0805120105  0.521
2008 Arbones-Mainar JM, Johnson LA, Altenburg MK, Maeda N. Differential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in mice. International Journal of Obesity (2005). 32: 1595-605. PMID 18725890 DOI: 10.1038/Ijo.2008.143  0.83
2008 Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lütjohann D, Kerksiek A, van Kruchten R, Maeda N, Staels B, van Bilsen M, Shiri-Sverdlov R, Hofker MH. Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis. Hepatology (Baltimore, Md.). 48: 474-86. PMID 18666236 DOI: 10.1002/Hep.22363  0.403
2008 Johnson LA, Altenburg MK, Walzem RL, Scanga LT, Maeda N. Absence of hyperlipidemia in LDL receptor-deficient mice having apolipoprotein B100 without the putative receptor-binding sequences. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1745-52. PMID 18617647 DOI: 10.1161/Atvbaha.108.169680  0.822
2008 Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, ... ... Maeda N, et al. Genes contributing to prion pathogenesis. The Journal of General Virology. 89: 1777-88. PMID 18559949 DOI: 10.1099/Vir.0.2008/001255-0  0.376
2008 Zhu X, Lee JY, Timmins JM, Brown JM, Boudyguina E, Mulya A, Gebre AK, Willingham MC, Hiltbold EM, Mishra N, Maeda N, Parks JS. Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. The Journal of Biological Chemistry. 283: 22930-41. PMID 18552351 DOI: 10.1074/Jbc.M801408200  0.366
2008 Altenburg M, Arbones-Mainar J, Johnson L, Wilder J, Maeda N. Human LDL receptor enhances sequestration of ApoE4 and VLDL remnants on the surface of hepatocytes but not their internalization in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1104-10. PMID 18369154 DOI: 10.1161/Atvbaha.108.164863  0.839
2008 Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, de Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM. Interference with PPARgamma signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling. Hypertension. 51: 867-71. PMID 18285614 DOI: 10.1161/Hypertensionaha.107.103648  0.669
2008 Gerritsen G, van der Hoogt CC, Schaap FG, Voshol PJ, Kypreos KE, Maeda N, Groen AK, Havekes LM, Rensen PC, van Dijk KW. ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency. Journal of Lipid Research. 49: 1048-55. PMID 18263930 DOI: 10.1194/Jlr.M800009-Jlr200  0.442
2008 Polisecki E, Muallem H, Maeda N, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Westendorp RG, de Craen AJ, Buckley BM, Ordovas JM, Schaefer EJ, et al. Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER. Atherosclerosis. 200: 109-14. PMID 18261733 DOI: 10.1016/J.Atherosclerosis.2007.12.004  0.325
2008 Brosnihan KB, Hodgin JB, Smithies O, Maeda N, Gallagher P. Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice. Experimental Physiology. 93: 658-64. PMID 18192335 DOI: 10.1113/Expphysiol.2007.041806  0.725
2008 Beyer AM, Baumbach GL, Halabi CM, Modrick ML, Lynch CM, Gerhold TD, Ghoneim SM, De Lange WJ, Keen HL, Tsai YS, Maeda N, Sigmund CD, Faraci FM. Interference with PPARγ signaling causes cerebral vascular dysfunction, hypertrophy, and remodeling (Hypertension (2008) 51, (867-871)) Hypertension. 51: e33. DOI: 10.1161/Hypertensionaha.108.009862  0.593
2007 Altenburg M, Homeister J, Doherty H, Maeda N. Genetics of atherosclerosis in murine models. Current Drug Targets. 8: 1161-71. PMID 18045094 DOI: 10.2174/138945007782403801  0.784
2007 Upmacis RK, Crabtree MJ, Deeb RS, Shen H, Lane PB, Benguigui LE, Maeda N, Hajjar DP, Gross SS. Profound biopterin oxidation and protein tyrosine nitration in tissues of ApoE-null mice on an atherogenic diet: contribution of inducible nitric oxide synthase. American Journal of Physiology. Heart and Circulatory Physiology. 293: H2878-87. PMID 17766468 DOI: 10.1152/Ajpheart.01144.2006  0.411
2007 Higuchi M, Yasuda O, Kawamoto H, Yotsui T, Baba Y, Ozaki T, Maeda N, Fukuo K, Rakugi H, Ogihara T. Tissue inhibitor of metalloproteinase-3 deficiency inhibits blood pressure elevation and myocardial microvascular remodeling induced by chronic administration of Nomega-nitro-L-arginine methyl ester in mice. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 30: 563-71. PMID 17664861 DOI: 10.1291/Hypres.30.563  0.335
2007 Carnicer R, Navarro MA, Arbonés-Mainar JM, Arnal C, Surra JC, Acín S, Sarría A, Blanco-Vaca F, Maeda N, Osada J. Genetically based hypertension generated through interaction of mild hypoalphalipoproteinemia and mild hyperhomocysteinemia. Journal of Hypertension. 25: 1597-607. PMID 17620955 DOI: 10.1097/Hjh.0B013E3281Ab6C3D  0.468
2007 Atshaves BP, McIntosh AL, Payne HR, Gallegos AM, Landrock K, Maeda N, Kier AB, Schroeder F. SCP-2/SCP-x gene ablation alters lipid raft domains in primary cultured mouse hepatocytes. Journal of Lipid Research. 48: 2193-211. PMID 17609524 DOI: 10.1194/Jlr.M700102-Jlr200  0.327
2007 Hsueh W, Abel ED, Breslow JL, Maeda N, Davis RC, Fisher EA, Dansky H, McClain DA, McIndoe R, Wassef MK, Rabadán-Diehl C, Goldberg IJ. Recipes for creating animal models of diabetic cardiovascular disease. Circulation Research. 100: 1415-27. PMID 17525381 DOI: 10.1161/01.Res.0000266449.37396.1F  0.313
2007 Ellmers LJ, Scott NJ, Piuhola J, Maeda N, Smithies O, Frampton CM, Richards AM, Cameron VA. Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis. Journal of Molecular Endocrinology. 38: 245-57. PMID 17293444 DOI: 10.1677/Jme.1.02138  0.594
2007 Maeda N, Johnson L, Kim S, Hagaman J, Friedman M, Reddick R. Anatomical differences and atherosclerosis in apolipoprotein E-deficient mice with 129/SvEv and C57BL/6 genetic backgrounds. Atherosclerosis. 195: 75-82. PMID 17275002 DOI: 10.1016/J.Atherosclerosis.2006.12.006  0.726
2007 Muallem H, North KE, Kakoki M, Wojczynski MK, Li X, Grove M, Boerwinkle E, Wilhelmsen KC, Heiss G, Maeda N. Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study. Human Genetics. 121: 421-31. PMID 17273844 DOI: 10.1007/S00439-007-0327-1  0.36
2007 Altenburg M, Johnson L, Wilder J, Maeda N. Apolipoprotein E4 in macrophages enhances atherogenesis in a low density lipoprotein receptor-dependent manner. The Journal of Biological Chemistry. 282: 7817-24. PMID 17234631 DOI: 10.1074/Jbc.M610712200  0.834
2007 Jones C, Garuti R, Michaely P, Li WP, Maeda N, Cohen JC, Herz J, Hobbs HH. Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. The Journal of Clinical Investigation. 117: 165-74. PMID 17200716 DOI: 10.1172/Jci29415  0.503
2007 Lucic D, Huang ZH, Gu de S, Altenburg MK, Maeda N, Mazzone T. Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor. Journal of Lipid Research. 48: 366-72. PMID 17079794 DOI: 10.1194/Jlr.M600259-Jlr200  0.789
2007 Atshaves BP, McIntosh AL, Landrock D, Payne HR, Mackie JT, Maeda N, Ball J, Schroeder F, Kier AB. Effect of SCP-x gene ablation on branched-chain fatty acid metabolism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G939-51. PMID 17068117 DOI: 10.1152/Ajpgi.00308.2006  0.362
2007 Maeda N, Givens RC, Reddick RL. Cardiovascular Disease: Mouse Models of Atherosclerosis The Mouse in Biomedical Research. 3: 535-563. DOI: 10.1016/B978-012369454-6/50070-4  0.32
2006 Li W, Maeda N, Beck MA. Vitamin C deficiency increases the lung pathology of influenza virus-infected gulo-/- mice. The Journal of Nutrition. 136: 2611-6. PMID 16988135 DOI: 10.1093/Jn/136.10.2611  0.36
2006 Guzmán MA, Navarro MA, Carnicer R, Sarría AJ, Acín S, Arnal C, Muniesa P, Surra JC, Arbonés-Mainar JM, Maeda N, Osada J. Cystathionine beta-synthase is essential for female reproductive function. Human Molecular Genetics. 15: 3168-76. PMID 16984962 DOI: 10.1093/Hmg/Ddl393  0.317
2006 Yuan W, Leisner TM, McFadden AW, Clark S, Hiller S, Maeda N, O'Brien DA, Parise LV. CIB1 is essential for mouse spermatogenesis. Molecular and Cellular Biology. 26: 8507-14. PMID 16982698 DOI: 10.1128/Mcb.01488-06  0.401
2006 Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Ishida-Okawara A, Suzuki K, Maeda N, Koyama H. Contribution of the myeloperoxidase-dependent oxidative system to host defence against Cryptococcus neoformans. Journal of Medical Microbiology. 55: 1291-9. PMID 16914663 DOI: 10.1099/Jmm.0.46620-0  0.419
2006 Yi X, Maeda N. alpha-Lipoic acid prevents the increase in atherosclerosis induced by diabetes in apolipoprotein E-deficient mice fed high-fat/low-cholesterol diet. Diabetes. 55: 2238-44. PMID 16873686 DOI: 10.2337/Db06-0251  0.392
2006 Tsai YS, Pendse A, Moy SS, Mohri I, Perez A, Crawley JN, Suzuki K, Maeda N. A de novo deafwaddler mutation of Pmca2 arising in ES cells and hitchhiking with a targeted modification of the Pparg gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 17: 716-22. PMID 16845470 DOI: 10.1007/S00335-005-0191-Z  0.784
2006 Komatsu J, Koyama H, Maeda N, Aratani Y. Earlier onset of neutrophil-mediated inflammation in the ultraviolet-exposed skin of mice deficient in myeloperoxidase and NADPH oxidase Inflammation Research. 55: 200-206. PMID 16830107 DOI: 10.1007/S00011-006-0071-3  0.411
2006 Yazama F, Furuta K, Fujimoto M, Sonoda T, Shigetomi H, Horiuchi T, Yamada M, Nagao N, Maeda N. Abnormal spermatogenesis in mice unable to synthesize ascorbic acid. Anatomical Science International. 81: 115-25. PMID 16800296 DOI: 10.1111/J.1447-073X.2006.00139.X  0.443
2006 Yasuda O, Fukuo K, Sun X, Nishitani M, Yotsui T, Higuchi M, Suzuki T, Rakugi H, Smithies O, Maeda N, Ogihara T. Apop-1, a novel protein inducing cyclophilin D-dependent but Bax/Bak-related channel-independent apoptosis. The Journal of Biological Chemistry. 281: 23899-907. PMID 16782708 DOI: 10.1074/Jbc.M512610200  0.466
2006 Kawamoto H, Yasuda O, Suzuki T, Ozaki T, Yotsui T, Higuchi M, Rakugi H, Fukuo K, Ogihara T, Maeda N. Tissue inhibitor of metalloproteinase-3 plays important roles in the kidney following unilateral ureteral obstruction. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 29: 285-94. PMID 16778336 DOI: 10.1291/Hypres.29.285  0.39
2006 Gaut JP, Belaaouaj A, Byun J, Roberts LJ, Maeda N, Frei B, Heinecke JW. Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation. Free Radical Biology & Medicine. 40: 1494-501. PMID 16632110 DOI: 10.1016/J.Freeradbiomed.2005.12.013  0.324
2006 Kakoki M, Kizer CM, Yi X, Takahashi N, Kim HS, Bagnell CR, Edgell CJ, Maeda N, Jennette JC, Smithies O. Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. The Journal of Clinical Investigation. 116: 1302-9. PMID 16604193 DOI: 10.1172/Jci26958  0.613
2006 Maezawa I, Maeda N, Montine TJ, Montine KS. Apolipoprotein E-specific innate immune response in astrocytes from targeted replacement mice. Journal of Neuroinflammation. 3: 10. PMID 16603079 DOI: 10.1186/1742-2094-3-10  0.364
2006 Kakoki M, Kim HS, Edgell CJ, Maeda N, Smithies O, Mattson DL. Amino acids as modulators of endothelium-derived nitric oxide. American Journal of Physiology. Renal Physiology. 291: F297-304. PMID 16571593 DOI: 10.1152/Ajprenal.00417.2005  0.452
2006 Mezdour H, Larigauderie G, Castro G, Torpier G, Fruchart J, Nowak M, Fruchart JC, Rouis M, Maeda N. Characterization of a new mouse model for human apolipoprotein A-I/C-III/A-IV deficiency. Journal of Lipid Research. 47: 912-20. PMID 16497661 DOI: 10.1194/Jlr.M500414-Jlr200  0.422
2006 Maezawa I, Nivison M, Montine KS, Maeda N, Montine TJ. Neurotoxicity from innate immune response is greatest with targeted replacement of E4 allele of apolipoprotein E gene and is mediated by microglial p38MAPK. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 797-9. PMID 16481366 DOI: 10.1096/Fj.05-5423Fje  0.323
2006 Shiri-Sverdlov R, Wouters K, van Gorp PJ, Gijbels MJ, Noel B, Buffat L, Staels B, Maeda N, van Bilsen M, Hofker MH. Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates. Journal of Hepatology. 44: 732-41. PMID 16466828 DOI: 10.1016/J.Jhep.2005.10.033  0.458
2006 Deeb RS, Shen H, Gamss C, Gavrilova T, Summers BD, Kraemer R, Hao G, Gross SS, Lainé M, Maeda N, Hajjar DP, Upmacis RK. Inducible nitric oxide synthase mediates prostaglandin h2 synthase nitration and suppresses eicosanoid production. The American Journal of Pathology. 168: 349-62. PMID 16400036 DOI: 10.2353/Ajpath.2006.050090  0.327
2006 Parsons KK, Maeda N, Yamauchi M, Banes AJ, Koller BH. Ascorbic acid-independent synthesis of collagen in mice. American Journal of Physiology. Endocrinology and Metabolism. 290: E1131-9. PMID 16352673 DOI: 10.1152/Ajpendo.00339.2005  0.371
2006 Nishikimi T, Maeda N, Matsuoka H. The role of natriuretic peptides in cardioprotection. Cardiovascular Research. 69: 318-28. PMID 16289003 DOI: 10.1016/J.Cardiores.2005.10.001  0.316
2006 Yasuda O, Fukuo K, Maeda N, Ogihara T. Elevated expression of type VIII collagen gene in the atherosclerotic plaque of the ApoE-deficient mouse. Annals of the New York Academy of Sciences. 947: 312-315. PMID 11795281 DOI: 10.1111/J.1749-6632.2001.Tb03954.X  0.381
2005 Hagaman JR, John S, Xu L, Smithies O, Maeda N. An improved technique for tail-cuff blood pressure measurements with dark-tailed mice. Contemporary Topics in Laboratory Animal Science / American Association For Laboratory Animal Science. 44: 43-6. PMID 16138782  0.5
2005 Yi X, Maeda N. Endogenous production of lipoic acid is essential for mouse development. Molecular and Cellular Biology. 25: 8387-92. PMID 16135825 DOI: 10.1128/Mcb.25.18.8387-8392.2005  0.421
2005 Acín S, Navarro MA, Carnicer R, Arbonés-Mainar JM, Guzmán MA, Arnal C, Beltrán G, Uceda M, Maeda N, Osada J. Dietary cholesterol suppresses the ability of olive oil to delay the development of atherosclerotic lesions in apolipoprotein E knockout mice. Atherosclerosis. 182: 17-28. PMID 16115471 DOI: 10.1016/J.Atherosclerosis.2005.01.050  0.341
2005 Tsai YS, Maeda N. PPARgamma: a critical determinant of body fat distribution in humans and mice. Trends in Cardiovascular Medicine. 15: 81-5. PMID 16039966 DOI: 10.1016/J.Tcm.2005.04.002  0.691
2005 Xiao H, Heeringa P, Liu Z, Huugen D, Hu P, Maeda N, Falk RJ, Jennette JC. The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. The American Journal of Pathology. 167: 39-45. PMID 15972950 DOI: 10.1016/S0002-9440(10)62951-3  0.337
2005 Guo J, Van Eck M, de Waard V, Maeda N, Benson GM, Groot PH, Van Berkel TJ. The presence of leukocyte CC-chemokine receptor 2 in CCR2 knockout mice promotes atherogenesis. Biochimica Et Biophysica Acta. 1740: 453-9. PMID 15949714 DOI: 10.1016/J.Bbadis.2004.10.007  0.378
2005 Hinsdale ME, Maeda N. Complex control of mouse apolipoprotein B gene expression revealed by targeted duplication. Biochimica Et Biophysica Acta. 1734: 178-89. PMID 15904874 DOI: 10.1016/J.Bbalip.2005.03.002  0.473
2005 Timmins JM, Lee JY, Boudyguina E, Kluckman KD, Brunham LR, Mulya A, Gebre AK, Coutinho JM, Colvin PL, Smith TL, Hayden MR, Maeda N, Parks JS. Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. The Journal of Clinical Investigation. 115: 1333-42. PMID 15841208 DOI: 10.1172/Jci23915  0.423
2005 Guo J, de Waard V, Van Eck M, Hildebrand RB, van Wanrooij EJ, Kuiper J, Maeda N, Benson GM, Groot PH, Van Berkel TJ. Repopulation of apolipoprotein E knockout mice with CCR2-deficient bone marrow progenitor cells does not inhibit ongoing atherosclerotic lesion development. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1014-9. PMID 15774908 DOI: 10.1161/01.Atv.0000163181.40896.42  0.335
2005 Nishikimi T, Hagaman JR, Takahashi N, Kim HS, Matsuoka H, Smithies O, Maeda N. Increased susceptibility to heart failure in response to volume overload in mice lacking natriuretic peptide receptor-A gene. Cardiovascular Research. 66: 94-103. PMID 15769452 DOI: 10.1016/J.Cardiores.2004.12.014  0.614
2005 Wang C, Wilson WA, Moore SD, Mace BE, Maeda N, Schmechel DE, Sullivan PM. Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology. Neurobiology of Disease. 18: 390-8. PMID 15686968 DOI: 10.1016/J.Nbd.2004.10.013  0.382
2005 Dubrac S, Lear SR, Ananthanarayanan M, Balasubramaniyan N, Bollineni J, Shefer S, Hyogo H, Cohen DE, Blanche PJ, Krauss RM, Batta AK, Salen G, Suchy FJ, Maeda N, Erickson SK. Role of CYP27A in cholesterol and bile acid metabolism. Journal of Lipid Research. 46: 76-85. PMID 15520450 DOI: 10.1194/Jlr.M400219-Jlr200  0.377
2004 Maezawa I, Jin LW, Woltjer RL, Maeda N, Martin GM, Montine TJ, Montine KS. Apolipoprotein E isoforms and apolipoprotein AI protect from amyloid precursor protein carboxy terminal fragment-associated cytotoxicity. Journal of Neurochemistry. 91: 1312-21. PMID 15584908 DOI: 10.1111/J.1471-4159.2004.02818.X  0.349
2004 Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Dinauer MC, Maeda N, Koyama H. In vivo role of myeloperoxidase for the host defense. Japanese Journal of Infectious Diseases. 57: S15. PMID 15507755  0.315
2004 Knouff C, Briand O, Lestavel S, Clavey V, Altenburg M, Maeda N. Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor. Biochimica Et Biophysica Acta. 1684: 8-17. PMID 15450205 DOI: 10.1016/J.Bbalip.2004.03.004  0.841
2004 Tsai YS, Kim HJ, Takahashi N, Kim HS, Hagaman JR, Kim JK, Maeda N. Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. The Journal of Clinical Investigation. 114: 240-9. PMID 15254591 DOI: 10.1172/Jci20964  0.694
2004 Maeda N, Funahashi T. Adiponectin knockout mice Nippon Rinsho. Japanese Journal of Clinical Medicine. 62: 1067-1076. PMID 15206143  0.342
2004 Kakoki M, Tsai YS, Kim HS, Hatada S, Ciavatta DJ, Takahashi N, Arnold LW, Maeda N, Smithies O. Altering the expression in mice of genes by modifying their 3' regions. Developmental Cell. 6: 597-606. PMID 15068798 DOI: 10.1016/S1534-5807(04)00094-2  0.753
2004 Klett EL, Lu K, Kosters A, Vink E, Lee MH, Altenburg M, Shefer S, Batta AK, Yu H, Chen J, Klein R, Looije N, Oude-Elferink R, Groen AK, Maeda N, et al. A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol. Bmc Medicine. 2: 5. PMID 15040800 DOI: 10.1186/1741-7015-2-5  0.766
2004 Sullivan PM, Mace BE, Maeda N, Schmechel DE. Marked regional differences of brain human apolipoprotein E expression in targeted replacement mice. Neuroscience. 124: 725-33. PMID 15026113 DOI: 10.1016/J.Neuroscience.2003.10.011  0.437
2004 Malloy SI, Altenburg MK, Knouff C, Lanningham-Foster L, Parks JS, Maeda N. Harmful effects of increased LDLR expression in mice with human APOE*4 but not APOE*3. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 91-7. PMID 12969990 DOI: 10.1161/01.Atv.0000094963.07902.Fb  0.826
2004 Raife TJ, Erger RA, Wilson KM, Fernandez JA, Alternburg J, Kim H, Griffin JH, Maeda N, Lentz SR. Targeted Replacement of the Murine Thrombomodulin Gene with Human Thrombomodulin Coding Sequence Results in Decreased Protein C Activation and Enhanced Thrombotic Response to Photochemical Injury. Blood. 104: 2980-2980. DOI: 10.1182/Blood.V104.11.2980.2980  0.461
2004 Altenburg MK, Malloy SI, Knouff C, Parks JS, Maeda N. ApoE4 trapping by the low density lipoprotein receptor International Congress Series. 1262: 388-391. DOI: 10.1016/j.ics.2003.11.035  0.768
2003 Hatada S, Grant DJ, Maeda N. An intronic endogenous retrovirus-like sequence attenuates human haptoglobin-related gene expression in an orientation-dependent manner. Gene. 319: 55-63. PMID 14597171 DOI: 10.1016/S0378-1119(03)00791-1  0.419
2003 Jinnouchi K, Terasaki Y, Fujiyama S, Tomita K, Kuziel WA, Maeda N, Takahashi K, Takeya M. Impaired hepatic granuloma formation in mice deficient in C-C chemokine receptor 2. The Journal of Pathology. 200: 406-16. PMID 12845637 DOI: 10.1002/Path.1362  0.461
2003 Dawson PA, Haywood J, Craddock AL, Wilson M, Tietjen M, Kluckman K, Maeda N, Parks JS. Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. The Journal of Biological Chemistry. 278: 33920-7. PMID 12819193 DOI: 10.1074/Jbc.M306370200  0.398
2003 Robert K, Chassé JF, Santiard-Baron D, Vayssettes C, Chabli A, Aupetit J, Maeda N, Kamoun P, London J, Janel N. Altered gene expression in liver from a murine model of hyperhomocysteinemia. The Journal of Biological Chemistry. 278: 31504-11. PMID 12799373 DOI: 10.1074/Jbc.M213036200  0.468
2003 Alexander MR, Knowles JW, Nishikimi T, Maeda N. Increased atherosclerosis and smooth muscle cell hypertrophy in natriuretic peptide receptor A-/-apolipoprotein E-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1077-82. PMID 12702516 DOI: 10.1161/01.Atv.0000071702.45741.2E  0.667
2003 Kuziel WA, Dawson TC, Quinones M, Garavito E, Chenaux G, Ahuja SS, Reddick RL, Maeda N. CCR5 deficiency is not protective in the early stages of atherogenesis in apoE knockout mice. Atherosclerosis. 167: 25-32. PMID 12618265 DOI: 10.1016/S0021-9150(02)00382-9  0.682
2003 Guo J, Van Eck M, Twisk J, Maeda N, Benson GM, Groot PH, Van Berkel TJ. Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 447-53. PMID 12615695 DOI: 10.1161/01.Atv.0000058431.78833.F5  0.37
2003 Knowles JW, Erickson LM, Guy VK, Sigel CS, Wilder JC, Maeda N. Common variations in noncoding regions of the human natriuretic peptide receptor A gene have quantitative effects. Human Genetics. 112: 62-70. PMID 12483301 DOI: 10.1007/S00439-002-0834-Z  0.601
2003 Ishida-Okawara A, Oharaseki T, Takahashi K, Hashimoto Y, Aratani Y, Koyama H, Maeda N, Naoe S, Suzuki K. Contribution of Myeloperoxidase to Coronary Artery Vasculitis Associated with MPO-ANCA Production Induced by Candida albicans -Derived Substances Pediatric Research. 53: 175-175. DOI: 10.1203/00006450-200301000-00129  0.452
2002 Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Dinauer MC, Maeda N, Koyama H. Relative contributions of myeloperoxidase and NADPH-oxidase to the early host defense against pulmonary infections with Candida albicans and Aspergillus fumigatus Medical Mycology. 40: 557-563. PMID 12521119 DOI: 10.1080/Mmy.40.6.557.563  0.407
2002 Hodgin JB, Maeda N. Minireview: estrogen and mouse models of atherosclerosis. Endocrinology. 143: 4495-501. PMID 12446574 DOI: 10.1210/En.2002-220844  0.643
2002 Adams MR, Golden DL, Register TC, Anthony MS, Hodgin JB, Maeda N, Williams JK. The atheroprotective effect of dietary soy isoflavones in apolipoprotein E-/- mice requires the presence of estrogen receptor-alpha. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1859-64. PMID 12426216 DOI: 10.1161/01.Atv.0000042202.42136.D0  0.695
2002 Hammond LE, Gallagher PA, Wang S, Hiller S, Kluckman KD, Posey-Marcos EL, Maeda N, Coleman RA. Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition. Molecular and Cellular Biology. 22: 8204-14. PMID 12417724 DOI: 10.1128/Mcb.22.23.8204-8214.2002  0.36
2002 Xiao H, Heeringa P, Hu P, Liu Z, Zhao M, Aratani Y, Maeda N, Falk RJ, Charles Jennette J. Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice Journal of Clinical Investigation. 110: 955-963. PMID 12370273 DOI: 10.1172/Jci15918  0.442
2002 Hinsdale ME, Sullivan PM, Mezdour H, Maeda N. ApoB-48 and apoB-100 differentially influence the expression of type-III hyperlipoproteinemia in APOE*2 mice Journal of Lipid Research. 43: 1520-1528. PMID 12235184 DOI: 10.1194/Jlr.M200103-Jlr200  0.523
2002 Choumenkovitch SF, Selhub J, Bagley PJ, Maeda N, Nadeau MR, Smith DE, Choi SW. In the cystathionine beta-synthase knockout mouse, elevations in total plasma homocysteine increase tissue S-adenosylhomocysteine, but responses of S-adenosylmethionine and DNA methylation are tissue specific. The Journal of Nutrition. 132: 2157-60. PMID 12163655 DOI: 10.1093/Jn/132.8.2157  0.413
2002 Magness ST, Maeda N, Brenner DA. An exon 10 deletion in the mouse ferrochelatase gene has a dominant-negative effect and causes mild protoporphyria. Blood. 100: 1470-7. PMID 12149233 DOI: 10.1182/Blood-2001-12-0283  0.404
2002 Ellmers LJ, Knowles JW, Kim HS, Smithies O, Maeda N, Cameron VA. Ventricular expression of natriuretic peptides in Npr1(-/-) mice with cardiac hypertrophy and fibrosis. American Journal of Physiology. Heart and Circulatory Physiology. 283: H707-14. PMID 12124219 DOI: 10.1152/Ajpheart.00677.2001  0.661
2002 Garg R, Oliver PM, Maeda N, Pandey KN. Genomic structure, organization, and promoter region analysis of murine guanylyl cyclase/atrial natriuretic peptide receptor-A gene. Gene. 291: 123-33. PMID 12095686 DOI: 10.1016/S0378-1119(02)00589-9  0.572
2002 Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Dinauer MC, Maeda N, Koyama H. Critical role of myeloperoxidase and nicotinamide adenine dinucleotide phosphate-oxidase in high-burden systemic infection of mice with Candida albicans. The Journal of Infectious Diseases. 185: 1833-7. PMID 12085336 DOI: 10.1086/340635  0.427
2002 Lyons MA, Maeda N, Brown AJ. Paradoxical enhancement of hepatic metabolism of 7-ketocholesterol in sterol 27-hydroxylase-deficient mice. Biochimica Et Biophysica Acta. 1581: 119-26. PMID 12020639 DOI: 10.1016/S1388-1981(02)00156-7  0.49
2002 Swardson-Olver CJ, Dawson TC, Burnett RC, Peiper SC, Maeda N, Avery AC. Plasmodium yoelii uses the murine Duffy antigen receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion. Blood. 99: 2677-84. PMID 11929753 DOI: 10.1182/Blood.V99.8.2677  0.578
2002 Nakata Y, Maeda N. Vulnerable atherosclerotic plaque morphology in apolipoprotein E-deficient mice unable to make ascorbic acid Circulation. 105: 1485-1490. PMID 11914259 DOI: 10.1161/01.Cir.0000012142.69612.25  0.4
2002 Kim HS, Lee G, John SW, Maeda N, Smithies O. Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proceedings of the National Academy of Sciences of the United States of America. 99: 4602-7. PMID 11904385 DOI: 10.1073/Pnas.072083799  0.59
2002 Wu JH, Hagaman J, Kim S, Reddick RL, Maeda N. Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 469-75. PMID 11884292 DOI: 10.1161/Hq0302.105287  0.428
2002 Hodgin JB, Knowles JW, Kim HS, Smithies O, Maeda N. Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice. The Journal of Clinical Investigation. 109: 541-8. PMID 11854327 DOI: 10.1172/Jci14066  0.795
2002 Hatada S, Seed JR, Barker C, Hajduk SL, Black S, Maeda N. No trypanosome lytic activity in the sera of mice producing human haptoglobin-related protein. Molecular and Biochemical Parasitology. 119: 291-4. PMID 11814582 DOI: 10.1016/S0166-6851(01)00420-0  0.41
2002 Takizawa S, Aratani Y, Fukuyama N, Maeda N, Hirabayashi H, Koyama H, Shinohara Y, Nakazawa H. Deficiency of myeloperoxidase increases infarct volume and nitrotyrosine formation in mouse brain Journal of Cerebral Blood Flow and Metabolism. 22: 50-54. PMID 11807393 DOI: 10.1097/00004647-200201000-00006  0.374
2002 Chantakru S, Miller C, Roach LE, Kuziel WA, Maeda N, Wang WC, Evans SS, Croy BA. Contributions from self-renewal and trafficking to the uterine NK cell population of early pregnancy. Journal of Immunology (Baltimore, Md. : 1950). 168: 22-8. PMID 11751942 DOI: 10.4049/Jimmunol.168.1.22  0.304
2001 Ishida-Okawara A, Oharaseki T, Takahashi K, Hashimoto Y, Aratani Y, Koyama H, Maeda N, Naoe S, Suzuki K. Contribution of myeloperoxidase to coronary artery vasculitis associated with MPO-ANCA production Inflammation. 25: 381-387. PMID 11831441 DOI: 10.1023/A:1012802714421  0.457
2001 Gilmore RC, Baker J, Dempsey S, Marchan R, Corprew RN, Byrd G, Maeda N, Smithies O, Bukoski RD, Harewood KR, Chatterjee PK. Using PAC nested deletions to order contigs and microsatellite markers at the high repetitive sequence containing Npr3 gene locus. Gene. 275: 65-72. PMID 11574153 DOI: 10.1016/S0378-1119(01)00654-0  0.483
2001 Fitzky BU, Moebius FF, Asaoka H, Waage-Baudet H, Xu L, Xu G, Maeda N, Kluckman K, Hiller S, Yu H, Batta AK, Shefer S, Chen T, Salen G, Sulik K, et al. 7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome. The Journal of Clinical Investigation. 108: 905-15. PMID 11560960 DOI: 10.1172/Jci12103  0.414
2001 Goy MF, Oliver PM, Purdy KE, Knowles JW, Fox JE, Mohler PJ, Qian X, Smithies O, Maeda N. Evidence for a novel natriuretic peptide receptor that prefers brain natriuretic peptide over atrial natriuretic peptide. The Biochemical Journal. 358: 379-87. PMID 11513736 DOI: 10.1042/0264-6021:3580379  0.735
2001 Hogan KA, Maeda N, Kluckman KD, Lord ST. Synthesis of a mouse model of the dysfibrinogen Vlissingen/Frankfurt IV. Annals of the New York Academy of Sciences. 936: 117-21. PMID 11460467 DOI: 10.1111/J.1749-6632.2001.Tb03498.X  0.371
2001 Dayal S, Bottiglieri T, Arning E, Maeda N, Malinow MR, Sigmund CD, Heistad DD, Faraci FM, Lentz SR. Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. Circulation Research. 88: 1203-9. PMID 11397788 DOI: 10.1161/Hh1101.092180  0.459
2001 Werstuck GH, Lentz SR, Dayal S, Hossain GS, Sood SK, Shi YY, Zhou J, Maeda N, Krisans SK, Malinow MR, Austin RC. Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways. The Journal of Clinical Investigation. 107: 1263-73. PMID 11375416 DOI: 10.1172/Jci11596  0.404
2001 Knowles JW, Esposito G, Mao L, Hagaman JR, Fox JE, Smithies O, Rockman HA, Maeda N. Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice. The Journal of Clinical Investigation. 107: 975-84. PMID 11306601 DOI: 10.1172/Jci11273  0.696
2001 Hodgin JB, Krege JH, Reddick RL, Korach KS, Smithies O, Maeda N. Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice. The Journal of Clinical Investigation. 107: 333-40. PMID 11160157 DOI: 10.1172/Jci11320  0.72
2001 Chantakru S, Kuziel WA, Maeda N, Croy BA. A study on the density and distribution of uterine Natural Killer cells at mid pregnancy in mice genetically-ablated for CCR2, CCR 5 and the CCR5 receptor ligand, MIP-1 alpha. Journal of Reproductive Immunology. 49: 33-47. PMID 11137111 DOI: 10.1016/S0165-0378(00)00076-0  0.314
2001 Knouff C, Malloy S, Wilder J, Altenburg MK, Maeda N. Doubling expression of the low density lipoprotein receptor by truncation of the 3'-untranslated region sequence ameliorates type iii hyperlipoproteinemia in mice expressing the human apoe2 isoform. The Journal of Biological Chemistry. 276: 3856-62. PMID 11076954 DOI: 10.1074/Jbc.M009423200  0.82
2001 Tsurubuchi T, Aratani Y, Maeda N, Koyama H. Retardation of early-onset PMA-induced apoptosis in mouse neutrophils deficient in myeloperoxidase. Journal of Leukocyte Biology. 70: 52-58. DOI: 10.1189/Jlb.70.1.52  0.315
2001 Knowles JW, Maeda N. Authors[rsquo ] reply: American Journal of Kidney Diseases. 37: 1322-1323. DOI: 10.1053/Ajkd.2001.23668  0.471
2000 Knowles JW, Maeda N. Genetic modifiers of atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 2336-45. PMID 11073835 DOI: 10.1161/01.Atv.20.11.2336  0.643
2000 Siebert H, Sachse A, Kuziel WA, Maeda N, Brück W. The chemokine receptor CCR2 is involved in macrophage recruitment to the injured peripheral nervous system Journal of Neuroimmunology. 110: 177-185. PMID 11024548 DOI: 10.1016/S0165-5728(00)00343-X  0.376
2000 Black TM, Wang P, Maeda N, Coleman RA. Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. The Journal of Nutrition. 130: 2420-6. PMID 11015467 DOI: 10.1093/Jn/130.10.2420  0.378
2000 Lamping KG, Nuno DW, Shesely EG, Maeda N, Faraci FM. Vasodilator mechanisms in the coronary circulation of endothelial nitric oxide synthase-deficient mice. American Journal of Physiology. Heart and Circulatory Physiology. 279: H1906-12. PMID 11009479 DOI: 10.1152/ajpheart.2000.279.4.H1906  0.324
2000 Lentz SR, Erger RA, Dayal S, Maeda N, Malinow MR, Heistad DD, Faraci FM. Folate dependence of hyperhomocysteinemia and vascular dysfunction in cystathionine β-synthase-deficient mice American Journal of Physiology-Heart and Circulatory Physiology. 279. PMID 10993757 DOI: 10.1152/Ajpheart.2000.279.3.H970  0.315
2000 Bush E, Maeda N, Kuziel WA, Dawson TC, Wilcox JN, DeLeon H, Taylor WR. CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension. Hypertension. 36: 360-3. PMID 10988265 DOI: 10.1161/01.Hyp.36.3.360  0.6
2000 Aratani Y, Kura F, Watanabe H, Akagawa H, Takano Y, Suzuki K, Maeda N, Koyama H. Differential host susceptibility to pulmonary infections with bacteria and fungi in mice deficient in myeloperoxidase Journal of Infectious Diseases. 182: 1276-1279. PMID 10979934 DOI: 10.1086/315843  0.372
2000 Dawson TC, Lentsch AB, Wang Z, Cowhig JE, Rot A, Maeda N, Peiper SC. Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC). Blood. 96: 1681-4. PMID 10961863 DOI: 10.1182/Blood.V96.5.1681  0.68
2000 Yasuda O, Zhang SH, Miyamoto Y, Maeda N. Differential expression of the alpha1 type VIII collagen gene by smooth muscle cells from atherosclerotic plaques of apolipoprotein-E-deficient mice. Journal of Vascular Research. 37: 158-69. PMID 10859474 DOI: 10.1159/000025727  0.36
2000 Dawson TC, Beck MA, Kuziel WA, Henderson F, Maeda N. Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus. The American Journal of Pathology. 156: 1951-9. PMID 10854218 DOI: 10.1016/S0002-9440(10)65068-7  0.636
2000 Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker HC. Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine. Journal of Immunology (Baltimore, Md. : 1950). 164: 6303-12. PMID 10843684 DOI: 10.4049/Jimmunol.164.12.6303  0.653
2000 Osada J, Joven J, Maeda N. The value of apolipoprotein E knockout mice for studying the effects of dietary fat and cholesterol on atherogenesis. Current Opinion in Lipidology. 11: 25-9. PMID 10750690 DOI: 10.1097/00041433-200002000-00004  0.426
2000 Heeringa P, van Goor H, Itoh-Lindstrom Y, Maeda N, Falk RJ, Assmann KJ, Kallenberg CG, Jennette JC. Lack of endothelial nitric oxide synthase aggravates murine accelerated anti-glomerular basement membrane glomerulonephritis. The American Journal of Pathology. 156: 879-88. PMID 10702405 DOI: 10.1016/S0002-9440(10)64957-7  0.44
2000 Knowles JW, Reddick RL, Jennette JC, Shesely EG, Smithies O, Maeda N. Enhanced atherosclerosis and kidney dysfunction in eNOS(-/-)Apoe(-/-) mice are ameliorated by enalapril treatment. The Journal of Clinical Investigation. 105: 451-8. PMID 10683374 DOI: 10.1172/Jci8376  0.735
2000 Maeda N, Hagihara H, Nakata Y, Hiller S, Wilder J, Reddick R. Aortic wall damage in mice unable to synthesize ascorbic acid. Proceedings of the National Academy of Sciences of the United States of America. 97: 841-6. PMID 10639167 DOI: 10.1073/Pnas.97.2.841  0.431
2000 Knowles J, Hodgin J, Maeda N. Genetic interaction between hypertension and atherosclerosis in mice Atherosclerosis. 151: 10. DOI: 10.1016/S0021-9150(00)80041-6  0.619
2000 Andres PO, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker H. Mice with a selective deletion of the chemokine receptors CCR5 or CCR2 are protected from DSS-mediated colitis: Lack of ccr5 expression results in TH2 type immune response in the intestine Gastroenterology. 118: A686. DOI: 10.1016/S0016-5085(00)84878-7  0.627
1999 Pandey KN, Oliver PM, Maeda N, Smithies O. Hypertension Associated with Decreased Testosterone Levels in Natriuretic Peptide Receptor-A Gene-Knockout and Gene-Duplicated Mutant Mouse Models1. Endocrinology. 140: 5112-5119. PMID 28204268 DOI: 10.1210/endo.140.11.7121  0.654
1999 Srivastava RAK, Toth L, Srivastava N, Hinsdale ME, Maeda N, Cefalu AB, Averna M, Schonfeld G. Regulation of the apolipoprotein B in heterozygous hypobetalipoproteinemic knock-out mice expressing truncated apoB, B81. Low production and enhanced clearance of apoB cause low levels of apoB Molecular and Cellular Biochemistry. 202: 37-46. PMID 10705993 DOI: 10.1023/A:1007030531478  0.426
1999 Pandey KN, Oliver PM, Maeda N, Smithies O. Hypertension associated with decreased testosterone levels in natriuretic peptide receptor-A gene-knockout and gene-duplicated mutant mouse models. Endocrinology. 140: 5112-9. PMID 10537139 DOI: 10.1210/Endo.140.11.7121  0.733
1999 Calleja L, París MA, Paul A, Vilella E, Joven J, Jiménez A, Beltrán G, Uceda M, Maeda N, Osada J. Low-cholesterol and high-fat diets reduce atherosclerotic lesion development in ApoE-knockout mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 2368-75. PMID 10521366 DOI: 10.1161/01.Atv.19.10.2368  0.332
1999 Mato M, Ookawara S, Mashiko T, Sakamoto A, Mato TK, Maeda N, Kodama T. Regional difference of lipid distribution in brain of apolipoprotein E deficient mice. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology. 256: 165-176. PMID 10486514 DOI: 10.1002/(Sici)1097-0185(19991001)256:2<165::Aid-Ar7>3.0.Co;2-Y  0.45
1999 Lake-Bruse KD, Faraci FM, Shesely EG, Maeda N, Sigmund CD, Heistad DD. Gene transfer of endothelial nitric oxide synthase (eNOS) in eNOS-deficient mice. The American Journal of Physiology. 277: H770-6. PMID 10444505 DOI: 10.1152/Ajpheart.1999.277.2.H770  0.434
1999 Knouff C, Hinsdale ME, Mezdour H, Altenburg MK, Watanabe M, Quarfordt SH, Sullivan PM, Maeda N. Apo E structure determines VLDL clearance and atherosclerosis risk in mice. The Journal of Clinical Investigation. 103: 1579-86. PMID 10359567 DOI: 10.1172/Jci6172  0.838
1999 Qi C, Zhu Y, Pan J, Usuda N, Maeda N, Yeldandi AV, Rao MS, Hashimoto T, Reddy JK. Absence of spontaneous peroxisome proliferation in enoyl-CoA Hydratase/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver. Further support for the role of fatty acyl CoA oxidase in PPARalpha ligand metabolism. The Journal of Biological Chemistry. 274: 15775-80. PMID 10336479 DOI: 10.1074/Jbc.274.22.15775  0.414
1999 Kim HS, Maeda N, Oh GT, Fernandez LG, Gomez RA, Smithies O. Homeostasis in mice with genetically decreased angiotensinogen is primarily by an increased number of renin-producing cells. The Journal of Biological Chemistry. 274: 14210-7. PMID 10318840 DOI: 10.1074/Jbc.274.20.14210  0.62
1999 Dawson TC, Kuziel WA, Osahar TA, Maeda N. Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient mice. Atherosclerosis. 143: 205-11. PMID 10208497 DOI: 10.1016/S0021-9150(98)00318-9  0.677
1999 Qi C, Zhu Y, Pan J, Yeldandi AV, Rao MS, Maeda N, Subbarao V, Pulikuri S, Hashimoto T, Reddy JK. Mouse steroid receptor coactivator-1 is not essential for peroxisome proliferator-activated receptor alpha-regulated gene expression. Proceedings of the National Academy of Sciences of the United States of America. 96: 1585-90. PMID 9990068 DOI: 10.1073/Pnas.96.4.1585  0.463
1999 Hatada S, Kuziel W, Smithies O, Maeda N. The influence of chromosomal location on the expression of two transgenes in mice. The Journal of Biological Chemistry. 274: 948-55. PMID 9873036 DOI: 10.1074/Jbc.274.2.948  0.553
1999 Aratani Y, Koyama H, Nyui SI, Suzuki K, Kura F, Maeda N. Severe Impairment in Early Host Defense against Candida albicans in Mice Deficient in Myeloperoxidase Infection and Immunity. 67: 1828-1836. DOI: 10.1128/Iai.67.4.1828-1836.1999  0.431
1998 Oliverio MI, Madsen K, Best CF, Ito M, Maeda N, Smithies O, Coffman TM. Renal growth and development in mice lacking ATreceptors for angiotensin II. American Journal of Physiology. Renal Physiology. 274: F43-F50. PMID 29592628 DOI: 10.1152/ajprenal.1998.274.1.F43  0.54
1998 Faraci FM, Sigmund CD, Shesely EG, Maeda N, Heistad DD. Responses of carotid artery in mice deficient in expression of the gene for endothelial NO synthase. American Journal of Physiology. Heart and Circulatory Physiology. 274: H564-H570. PMID 29586063 DOI: 10.1152/Ajpheart.1998.274.2.H564  0.409
1998 Osada J, Maeda N. Preparation of knockout mice Methods in Molecular Biology (Clifton, N.J.). 110: 79-92. PMID 9918040 DOI: 10.1385/1-59259-582-0:79  0.445
1998 Reddick RL, Zhang SH, Maeda N. Aortic atherosclerotic plaque injury in apolipoprotein E deficient mice Atherosclerosis. 140: 297-305. PMID 9862272 DOI: 10.1016/S0021-9150(98)00133-6  0.355
1998 Oliverio MI, Kim HS, Ito M, Le T, Audoly L, Best CF, Hiller S, Kluckman K, Maeda N, Smithies O, Coffman TM. Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II. Proceedings of the National Academy of Sciences of the United States of America. 95: 15496-501. PMID 9860997 DOI: 10.1073/Pnas.95.26.15496  0.598
1998 Sullivan PM, Mezdour H, Quarfordt SH, Maeda N. Type III hyperlipoproteinemia and spontaneous atherosclerosis in mice resulting from gene replacement of mouse Apoe with human APOE*2 Journal of Clinical Investigation. 102: 130-135. PMID 9649566 DOI: 10.1172/Jci2673  0.542
1998 Braschi S, Couture N, Gambarotta A, Gauthier BR, Coffill CR, Sparks DL, Maeda N, Schultz JR. Hepatic lipase affects both HDL and ApoB-containing lipoprotein levels in the mouse. Biochimica Et Biophysica Acta. 1392: 276-90. PMID 9630674 DOI: 10.1016/S0005-2760(98)00046-0  0.42
1998 Rosen H, Reshef A, Maeda N, Lippoldt A, Shpizen S, Triger L, Eggertsen G, Björkhem I, Leitersdorf E. Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27- hydroxylase gene Journal of Biological Chemistry. 273: 14805-14812. PMID 9614081 DOI: 10.1074/Jbc.273.24.14805  0.42
1998 Outinen PA, Sood SK, Liaw PC, Sarge KD, Maeda N, Hirsh J, Ribau J, Podor TJ, Weitz JI, Austin RC. Characterization of the stress-inducing effects of homocysteine. The Biochemical Journal. 332: 213-21. PMID 9576870 DOI: 10.1042/Bj3320213  0.317
1998 Zhu Z, Zhang SH, Wagner C, Kurtz A, Maeda N, Coffman T, Arendshorst WJ. Angiotensin AT(1B) receptor mediates calcium signaling in vascular smooth muscle cells of AT(1A) receptor-deficient mice Hypertension. 31: 1171-1177. PMID 9576131 DOI: 10.1161/01.Hyp.31.5.1171  0.304
1998 Roses AD, Gilbert J, Xu PT, Sullivan P, Popko B, Burkhart DS, Christian-Rothrock T, Saunders AM, Maeda N, Schmechel DE. Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiology of Aging. 19: S53-8. PMID 9562469 DOI: 10.1016/S0197-4580(98)00030-X  0.464
1998 Seedorf U, Raabe M, Ellinghaus P, Kannenberg F, Fobker M, Engel T, Denis S, Wouters F, Wirtz KW, Wanders RJ, Maeda N, Assmann G. Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2/sterol carrier protein-x gene function. Genes & Development. 12: 1189-201. PMID 9553048 DOI: 10.1101/Gad.12.8.1189  0.395
1998 Lewis J, Yang B, Kim R, Sierakowska H, Kole R, Smithies O, Maeda N. A common human beta globin splicing mutation modeled in mice. Blood. 91: 2152-6. PMID 9490703 DOI: 10.1182/Blood.V91.6.2152.2152_2152_2156  0.76
1998 Oliver PM, John SW, Purdy KE, Kim R, Maeda N, Goy MF, Smithies O. Natriuretic peptide receptor 1 expression influences blood pressures of mice in a dose-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 95: 2547-51. PMID 9482923 DOI: 10.1073/Pnas.95.5.2547  0.683
1998 Rudic RD, Shesely EG, Maeda N, Smithies O, Segal SS, Sessa WC. Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling. The Journal of Clinical Investigation. 101: 731-6. PMID 9466966 DOI: 10.1172/Jci1699  0.54
1998 Oliverio MI, Madsen K, Best CF, Ito M, Maeda N, Smithies O, Coffman TM. Renal growth and development in mice lacking AT1A receptors for angiotensin II. The American Journal of Physiology. 274: F43-50. PMID 9458822 DOI: 10.1152/Ajprenal.1998.274.1.F43  0.599
1998 Fujita N, Kemper A, Dupree J, Nakayasu H, Bartsch U, Schachner M, Maeda N, Suzuki K, Suzuki K, Popko B. The Cytoplasmic Domain of the Large Myelin-Associated Glycoprotein Isoform Is Needed for Proper CNS But Not Peripheral Nervous System Myelination The Journal of Neuroscience. 18: 1970-1978. DOI: 10.1523/Jneurosci.18-06-01970.1998  0.315
1998 Lewis J, Yang B, Kim R, Sierakowska H, Kole R, Smithies O, Maeda N. A Common Human β Globin Splicing Mutation Modeled in Mice Blood. 91: 2152-2156. DOI: 10.1182/blood.V91.6.2152.2152_2152_2156  0.567
1997 Oliver PM, Fox JE, Kim R, Rockman HA, Kim HS, Reddick RL, Pandey KN, Milgram SL, Smithies O, Maeda N. Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A. Proceedings of the National Academy of Sciences of the United States of America. 94: 14730-5. PMID 9405681 DOI: 10.1073/Pnas.94.26.14730  0.706
1997 Lanoue L, Dehart DB, Hinsdale ME, Maeda N, Tint GS, Sulik KK. Limb, genital, CNS, and facial malformations result from gene/environment-induced cholesterol deficiency: further evidence for a link to sonic hedgehog. American Journal of Medical Genetics. 73: 24-31. PMID 9375918 DOI: 10.1002/(Sici)1096-8628(19971128)73:1<24::Aid-Ajmg6>3.0.Co;2-P  0.399
1997 Lin HF, Maeda N, Smithies O, Straight DL, Stafford DW. A coagulation factor IX-deficient mouse model for human hemophilia B. Blood. 90: 3962-6. PMID 9354664 DOI: 10.1182/Blood.V90.10.3962  0.554
1997 Huang Y, Zhu Y, Langer C, Raabe M, Wu S, Wiesenhütter B, Seedorf U, Maeda N, Assmann G, von Eckardstein A. Effects of genotype and diet on cholesterol efflux into plasma and lipoproteins of normal, apolipoprotein A-I-, and apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2010-9. PMID 9351366 DOI: 10.1161/01.Atv.17.10.2010  0.414
1997 Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, Ley K, Maeda N. Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proceedings of the National Academy of Sciences of the United States of America. 94: 12053-8. PMID 9342361 DOI: 10.1073/Pnas.94.22.12053  0.741
1997 Krege JH, Moyer JS, Langenbach LL, Peng L, Zhang SH, Maeda N, Reddick RL, Smithies O. Angiotensin-converting enzyme gene and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 1245-50. PMID 9261253 DOI: 10.1161/Atvb.17V07.1245  0.568
1997 Sullivan PM, Mezdour H, Aratani Y, Knouff C, Najib J, Reddick RL, Quarfordt SH, Maeda N. Targeted replacement of the mouse apolipoprotein E gene with the common human APOE3 allele enhances diet-induced hypercholesterolemia and atherosclerosis Journal of Biological Chemistry. 272: 17972-17980. PMID 9218423 DOI: 10.1074/Jbc.272.29.17972  0.839
1997 Tsuda H, Maynard-Currie CE, Reid LH, Yoshida T, Edamura K, Maeda N, Smithies O, Jakobovits A. Inactivation of the mouse HPRT locus by a 203-bp retroposon insertion and a 55-kb gene-targeted deletion: establishment of new HPRT-deficient mouse embryonic stem cell lines. Genomics. 42: 413-21. PMID 9205113 DOI: 10.1006/Geno.1997.4771  0.54
1997 Zhang SH, Reddick RL, Avdievich E, Surles LK, Jones RG, Reynolds JB, Quarfordt SH, Maeda N. Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice Journal of Clinical Investigation. 99: 2858-2866. PMID 9185508 DOI: 10.1172/Jci119479  0.501
1997 Mezdour H, Jones R, Dengremont C, Castro G, Maeda N. Hepatic lipase deficiency increases plasma cholesterol but reduces susceptibility to atherosclerosis in apolipoprotein E-deficient mice. The Journal of Biological Chemistry. 272: 13570-5. PMID 9153204 DOI: 10.1074/Jbc.272.21.13570  0.449
1997 Suzuki H, Kurihara Y, Takeya M, Kamada N, Kataoka M, Jishage K, Ueda O, Sakaguchi H, Higashi T, Suzuki T, Takashima Y, Kawabe Y, Cynshi O, Wada Y, Honda M, ... ... Maeda N, et al. A role for macrophage scavenger receptors in atherosclerosis and susceptibility to infection Nature. 386: 292-296. PMID 9069289 DOI: 10.1038/386292A0  0.461
1997 Fan CY, Pan J, Chu R, Lee D, Kluckman KD, Usuda N, Singh I, Yeldandi AV, Rao MS, Maeda N, Reddy JK. Targeted disruption of the peroxisomal fatty acyl-CoA oxidase gene: generation of a mouse model of pseudoneonatal adrenoleukodystrophy. Annals of the New York Academy of Sciences. 804: 530-41. PMID 8993571 DOI: 10.1111/J.1749-6632.1996.Tb18643.X  0.32
1997 Sullivan P, Mezdour H, Maeda N. 4.P.401 Type III hyperlipoproteinemia and increased susceptibility to atherosclerosis in human apolipoprotein E2 gene replacement mice Atherosclerosis. 134: 381. DOI: 10.1016/S0021-9150(97)89928-5  0.45
1997 Majd Z, Gbaguidi F, Fruchart J, Sullivan P, Maeda N, Mezdour H, Gesquière J, Najib J. 1.P.16 Enzyme-linked immunosorbent assay for apolipoprotein E in mice serum Atherosclerosis. 134: 20. DOI: 10.1016/S0021-9150(97)88197-X  0.377
1997 Maeda N. Genetic analysis of atherosclerosis in mice Faseb Journal. 11.  0.32
1996 Xu PT, Schmechel D, Rothrock-Christian T, Burkhart DS, Qiu HL, Popko B, Sullivan P, Maeda N, Saunders AM, Roses AD, Gilbert JR. Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiology of Disease. 3: 229-45. PMID 8980023 DOI: 10.1006/Nbdi.1996.0023  0.474
1996 Toth LR, Smith TJ, Jones C, de Silva HV, Smithies O, Maeda N. Two distinct apolipoprotein B alleles in mice generated by a single 'in-out' targeting. Gene. 178: 161-8. PMID 8921909 DOI: 10.1016/0378-1119(96)00360-5  0.58
1996 Shesely EG, Maeda N, Kim HS, Desai KM, Krege JH, Laubach VE, Sherman PA, Sessa WC, Smithies O. Elevated blood pressures in mice lacking endothelial nitric oxide synthase. Proceedings of the National Academy of Sciences of the United States of America. 93: 13176-81. PMID 8917564 DOI: 10.1073/Pnas.93.23.13176  0.633
1996 Bronson SK, Plaehn EG, Kluckman KD, Hagaman JR, Maeda N, Smithies O. Single-copy transgenic mice with chosen-site integration. Proceedings of the National Academy of Sciences of the United States of America. 93: 9067-72. PMID 8799155 DOI: 10.1073/Pnas.93.17.9067  0.576
1996 Fan CY, Pan J, Chu R, Lee D, Kluckman KD, Usuda N, Singh I, Yeldandi AV, Rao MS, Maeda N, Reddy JK. Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene. The Journal of Biological Chemistry. 271: 24698-710. PMID 8798738 DOI: 10.1074/Jbc.271.40.24698  0.432
1996 Fujita N, Suzuki K, Vanier MT, Popko B, Maeda N, Klein A, Henseler M, Sandhoff K, Nakayasu H, Suzuki K. Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids. Human Molecular Genetics. 5: 711-25. PMID 8776585 DOI: 10.1093/Hmg/5.6.711  0.34
1996 Chang S, Maeda N, Borensztajn J. The role of lipoprotein lipase and apoprotein E in the recognition of chylomicrons and chylomicron remnants by cultured isolated mouse hepatocytes. The Biochemical Journal. 29-34. PMID 8761448 DOI: 10.1042/Bj3180029  0.392
1996 Tatzelt J, Maeda N, Pekny M, Yang SL, Betsholtz C, Eliasson C, Cayetano J, Camerino AP, DeArmond SJ, Prusiner SB. Scrapie in mice deficient in apolipoprotein E or glial fibrillary acidic protein. Neurology. 47: 449-53. PMID 8757019 DOI: 10.1212/WNL.47.2.449  0.357
1996 Applebaum-Bowden D, Kobayashi J, Kashyap VS, Brown DR, Berard A, Meyn S, Parrott C, Maeda N, Shamburek R, Brewer HB, Santamarina-Fojo S. Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirus-mediated replacement of a lipolytic enzyme to the vascular endothelium. The Journal of Clinical Investigation. 97: 799-805. PMID 8609237 DOI: 10.1172/Jci118479  0.454
1996 Kobayashi J, Applebaum-Bowden D, Dugi KA, Brown DR, Kashyap VS, Parrott C, Duarte C, Maeda N, Santamarina-Fojo S. Analysis of Protein Structure-Functionin Vivo Journal of Biological Chemistry. 271: 26296-26301. DOI: 10.1074/Jbc.271.42.26296  0.393
1995 Yang B, Kirby S, Lewis J, Detloff PJ, Maeda N, Smithies O. A mouse model for beta 0-thalassemia. Proceedings of the National Academy of Sciences of the United States of America. 92: 11608-12. PMID 8524813 DOI: 10.1073/Pnas.92.25.11608  0.713
1995 Watanabe M, Osada J, Aratani Y, Kluckman K, Reddick R, Malinow MR, Maeda N. Mice deficient in cystathionine β-synthase: Animal models for mild and severe homocyst(e)inemia Proceedings of the National Academy of Sciences of the United States of America. 92: 1585-1589. PMID 7878023 DOI: 10.1073/Pnas.92.5.1585  0.393
1995 Homanics GE, de Silva HV, Osada J, Zhang SH, Wong H, Borensztajn J, Maeda N. Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene. The Journal of Biological Chemistry. 270: 2974-80. PMID 7852377 DOI: 10.1074/Jbc.270.7.2974  0.375
1995 Feingold KR, Elias PM, Mao-Qiang M, Fartasch M, Zhang SH, Maeda N. Apolipoprotein E deficiency leads to cutaneous foam cell formation in mice. The Journal of Investigative Dermatology. 104: 246-50. PMID 7829881 DOI: 10.1111/1523-1747.Ep12612790  0.458
1995 Goodrum JF, Bouldin TW, Zhang SH, Maeda N, Popko B. Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice. Journal of Neurochemistry. 64: 408-16. PMID 7798939 DOI: 10.1046/J.1471-4159.1995.64010408.X  0.331
1995 Smithies O, Maeda N. Gene targeting approaches to complex genetic diseases: atherosclerosis and essential hypertension. Proceedings of the National Academy of Sciences of the United States of America. 92: 5266-72. PMID 7777495 DOI: 10.1073/Pnas.92.12.5266  0.533
1995 Coleman T, Seip RL, Gimble JM, Lee D, Maeda N, Semenkovich CF. COOH-terminal disruption of lipoprotein lipase in mice is lethal in homozygotes, but heterozygotes have elevated triglycerides and impaired enzyme activity Journal of Biological Chemistry. 270: 12518-12525. PMID 7759497 DOI: 10.1074/Jbc.270.21.12518  0.451
1995 Ito M, Oliverio MI, Mannon PJ, Best CF, Maeda N, Smithies O, Coffman TM. Regulation of blood pressure by the type 1A angiotensin II receptor gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 3521-5. PMID 7724593 DOI: 10.1073/Pnas.92.8.3521  0.581
1995 Kim HS, Krege JH, Kluckman KD, Hagaman JR, Hodgin JB, Best CF, Jennette JC, Coffman TM, Maeda N, Smithies O. Genetic control of blood pressure and the angiotensinogen locus. Proceedings of the National Academy of Sciences of the United States of America. 92: 2735-9. PMID 7708716 DOI: 10.1073/Pnas.92.7.2735  0.712
1995 Kashyap VS, Santamarina-Fojo S, Brown DR, Parrott CL, Applebaum-Bowden D, Meyn S, Talley G, Paigen B, Maeda N, Brewer HB. Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors. The Journal of Clinical Investigation. 96: 1612-20. PMID 7657831 DOI: 10.1172/Jci118200  0.496
1995 Homanics GE, Maeda N, Traber MG, Kayden HJ, Dehart DB, Sulik KK. Exencephaly and hydrocephaly in mice with targeted modification of the apolipoprotein B (Apob) gene. Teratology. 51: 1-10. PMID 7597652 DOI: 10.1002/Tera.1420510102  0.457
1994 Reddick RL, Zhang SH, Maeda N. Atherosclerosis in mice lacking Apo E - Evaluation of lesional development and progression Arteriosclerosis, Thrombosis, and Vascular Biology. 14: 141-147. PMID 8274470 DOI: 10.1161/01.Atv.14.1.141  0.414
1994 Ishibashi S, Herz J, Maeda N, Goldstein JL, Brown MS. The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 4431-5. PMID 8183926 DOI: 10.1073/Pnas.91.10.4431  0.522
1994 Huang Y, Eckardstein AV, Wu S, Maeda N, Assmann G. A plasma lipoprotein containing only apolipoprotein E and with gamma mobility on electrophoresis releases cholesterol from cells. Proceedings of the National Academy of Sciences of the United States of America. 91: 1834-1838. PMID 8127890 DOI: 10.1073/Pnas.91.5.1834  0.395
1994 Zhang SH, Reddick RL, Burkey B, Maeda N. Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption Journal of Clinical Investigation. 94: 937-945. PMID 8083379 DOI: 10.1172/Jci117460  0.481
1994 Pászty C, Maeda N, Verstuyft J, Rubin EM. Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. The Journal of Clinical Investigation. 94: 899-903. PMID 8040345 DOI: 10.1172/Jci117412  0.486
1994 Chang S, Zhang SH, Maeda N, Borensztajn J. Hepatic clearance of chylomicron remnants in mice lacking apoprotein E. Biochimica Et Biophysica Acta. 1215: 205-8. PMID 7948005 DOI: 10.1016/0005-2760(94)90112-0  0.424
1994 Detloff PJ, Lewis J, John SW, Shehee WR, Langenbach R, Maeda N, Smithies O. Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy. Molecular and Cellular Biology. 14: 6936-43. PMID 7935410 DOI: 10.1128/Mcb.14.10.6936  0.668
1993 Homanics GE, Smith TJ, Zhang SH, Lee D, Young SG, Maeda N. Targeted modification of the apolipoprotein B gene results in hypobetalipoproteinemia and developmental abnormalities in mice. Proceedings of the National Academy of Sciences of the United States of America. 90: 2389-93. PMID 8460149 DOI: 10.1073/Pnas.90.6.2389  0.49
1993 Popko B, Goodrum JF, Bouldin TW, Zhang SH, Maeda N. Nerve regeneration occurs in the absence of apolipoprotein E in mice. Journal of Neurochemistry. 60: 1155-8. PMID 8436967 DOI: 10.1111/J.1471-4159.1993.Tb03268.X  0.325
1993 Kim HS, Lyons KM, Saitoh E, Azen EA, Smithies O, Maeda N. The structure and evolution of the human salivary proline-rich protein gene family. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 3-14. PMID 8422499 DOI: 10.1007/Bf00364656  0.505
1993 Li H, Reddick RL, Maeda N. Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice Arteriosclerosis, Thrombosis, and Vascular Biology. 13: 1814-1821. PMID 8241102 DOI: 10.1161/01.Atv.13.12.1814  0.493
1993 Maeda N. Gene targeting in mice as a strategy for understanding lipid metabolism and atherogenesis Current Opinion in Lipidology. 4: 90-94. DOI: 10.1097/00041433-199304000-00003  0.43
1992 Piedrahita JA, Zhang SH, Hagaman JR, Oliver PM, Maeda N. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 89: 4471-5. PMID 1584779 DOI: 10.1073/Pnas.89.10.4471  0.622
1992 Williamson R, Lee D, Hagaman J, Maeda N. Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I. Proceedings of the National Academy of Sciences of the United States of America. 89: 7134-8. PMID 1496008 DOI: 10.1073/Pnas.89.15.7134  0.435
1992 Zhang SH, Reddick RL, Piedrahita JA, Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E Science. 258: 468-471. PMID 1411543 DOI: 10.1126/Science.1411543  0.475
1991 Schwartz F, Maeda N, Smithies O, Hickey R, Edelmann W, Skoultchi A, Kucherlapati R. A dominant positive and negative selectable gene for use in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10416-20. PMID 1720540 DOI: 10.1073/Pnas.88.23.10416  0.489
1990 Smith TJ, Hautamaa D, Maeda N. Sequence of the putative low-density lipoprotein receptor-binding regions of apolipoprotein B in mouse and hamster. Gene. 87: 309-10. PMID 2332175 DOI: 10.1016/0378-1119(90)90319-M  0.343
1990 Kim HS, Smithies O, Maeda N. A physical map of the human salivary proline-rich protein gene cluster covers over 700 kbp of DNA. Genomics. 6: 260-7. PMID 2307469 DOI: 10.1016/0888-7543(90)90565-C  0.477
1989 Koller BH, Hagemann LJ, Doetschman T, Hagaman JR, Huang S, Williams PJ, First NL, Maeda N, Smithies O. Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 86: 8927-31. PMID 2573070 DOI: 10.1073/Pnas.86.22.8927  0.566
1988 Doetschman T, Maeda N, Smithies O. Targeted mutation of the Hprt gene in mouse embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 8583-7. PMID 3186749 DOI: 10.1073/Pnas.85.22.8583  0.496
1987 Doetschman T, Gregg RG, Maeda N, Hooper ML, Melton DW, Thompson S, Smithies O. Targetted correction of a mutant HPRT gene in mouse embryonic stem cells. Nature. 330: 576-8. PMID 3683574 DOI: 10.1038/330576A0  0.527
1987 Saitoh E, Kim HS, Smithies O, Maeda N. Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family. Gene. 61: 329-38. PMID 3446578 DOI: 10.1016/0378-1119(87)90196-X  0.501
1987 Song KY, Schwartz F, Maeda N, Smithies O, Kucherlapati R. Accurate modification of a chromosomal plasmid by homologous recombination in human cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 6820-4. PMID 2821545 DOI: 10.1073/Pnas.84.19.6820  0.528
1986 Maeda N, Smithies O. The evolution of multigene families: human haptoglobin genes. Annual Review of Genetics. 20: 81-108. PMID 2880559 DOI: 10.1146/Annurev.Ge.20.120186.000501  0.494
1986 Maeda N, McEvoy SM, Harris HF, Huisman TH, Smithies O. Polymorphisms in the human haptoglobin gene cluster: chromosomes with multiple haptoglobin-related (Hpr) genes. Proceedings of the National Academy of Sciences of the United States of America. 83: 7395-9. PMID 2876426 DOI: 10.1073/Pnas.83.19.7395  0.503
1984 Maeda N, Yang F, Barnett DR, Bowman BH, Smithies O. Duplication within the haptoglobin Hp2 gene. Nature. 309: 131-5. PMID 6325933 DOI: 10.1038/309131A0  0.508
1984 Azen E, Lyons KM, McGonigal T, Barrett NL, Clements LS, Maeda N, Vanin EF, Carlson DM, Smithies O. Clones from the human gene complex coding for salivary proline-rich proteins. Proceedings of the National Academy of Sciences of the United States of America. 81: 5561-5. PMID 6089212 DOI: 10.1073/Pnas.81.17.5561  0.485
1983 Maeda N, Bliska JB, Smithies O. Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 80: 5012-6. PMID 6308666 DOI: 10.1073/Pnas.80.16.5012  0.489
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