Andrew K. Godwin - Publications

Affiliations: 
Biochemistry and Molecular Biology Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
Molecular Biology, Biostatistics Biology

201 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Gupta VG, Hirst J, Petersen S, Roby KF, Kusch M, Zhou H, Clive ML, Jewell A, Pathak HB, Godwin AK, Wilson AJ, Crispens MA, Cybulla E, Vindigni A, Fuh KC, et al. Entinostat, a selective HDAC1/2 inhibitor, potentiates the effects of olaparib in homologous recombination proficient ovarian cancer. Gynecologic Oncology. PMID 33867143 DOI: 10.1016/j.ygyno.2021.04.015  0.316
2020 Kim O, Park EY, Kwon SY, Shin S, Emerson RE, Shin YH, DeMayo FJ, Lydon JP, Coffey DM, Hawkins SM, Quilliam LA, Cheon DJ, Fernández FM, Nephew KP, Karpf AR, ... ... Godwin AK, et al. Targeting progesterone signaling prevents metastatic ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 33262282 DOI: 10.1073/pnas.2013595117  0.341
2020 Rose IM, Bidarimath M, Webster A, Godwin AK, Flesken-Nikitin A, Nikitin AY. WNT and inflammatory signaling distinguish human Fallopian tube epithelial cell populations. Scientific Reports. 10: 9837. PMID 32555344 DOI: 10.1038/S41598-020-66556-Y  0.343
2020 Zhang H, Ahearn TU, Lecarpentier J, Barnes D, Beesley J, Qi G, Jiang X, O'Mara TA, Zhao N, Bolla MK, Dunning AM, Dennis J, Wang Q, Ful ZA, Aittomäki K, ... ... Godwin AK, et al. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nature Genetics. PMID 32424353 DOI: 10.1038/s41588-020-0609-2  0.323
2020 Trinidad CV, Tetlow AL, Bantis LE, Godwin AK. Reducing Ovarian Cancer Mortality Through Early Detection: Approaches Using Circulating Biomarkers. Cancer Prevention Research (Philadelphia, Pa.). 13: 241-252. PMID 32132118 DOI: 10.1158/1940-6207.CAPR-19-0184  0.302
2019 Telfah M, Iwakuma T, Bur A, Shnayder L, Tsue T, Al-Kasspooles MM, Ashcraft J, Martin B, Al-Rajabi RMT, Kasi A, Khan QJ, Lin TL, Saeed A, Williamson SK, Chalise P, ... Godwin AK, et al. A window of opportunity trial of atorvastatin in p53-mutant and p53 wild type malignancies. Journal of Clinical Oncology. 37. DOI: 10.1200/Jco.2019.37.15_Suppl.Tps3165  0.315
2018 Lu Y, Beeghly-Fadiel A, Wu L, Guo X, Li B, Schildkraut JM, Im HK, Chen YA, Permuth JB, Reid BM, Teer JK, Moysich KB, Andrulis IL, Anton-Culver H, Arun BK, ... ... Godwin AK, et al. A transcriptome-wide association study among 97,898 women to identify candidate susceptibility genes for epithelial ovarian cancer risk. Cancer Research. PMID 30054336 DOI: 10.1158/0008-5472.Can-18-0951  0.36
2018 Hirst J, Pathak HB, Hyter S, Pessetto ZY, Ly T, Graw S, Koestler DC, Krieg AJ, Roby KF, Godwin AK. Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties. Cancer Research. PMID 29891506 DOI: 10.1158/0008-5472.CAN-17-3993  0.304
2018 Hyter S, Hirst J, Pathak H, Pessetto ZY, Koestler DC, Raghavan R, Pei D, Godwin AK. Developing a genetic signature to predict drug response in ovarian cancer. Oncotarget. 9: 14828-14848. PMID 29599910 DOI: 10.18632/oncotarget.23663  0.317
2018 Li LX, Zhou JX, Calvet JP, Godwin AK, Jensen RA, Li X. Lysine methyltransferase SMYD2 promotes triple negative breast cancer progression. Cell Death & Disease. 9: 326. PMID 29487338 DOI: 10.1038/S41419-018-0347-X  0.306
2018 Kasi A, Chidharla A, Schmitt S, Pessetto ZY, Gupta N, Paluri RK, Saeed AM, Godwin AK. ALK alteration association with prognosis in metastatic colorectal cancer: A single institution retrospective cohort study. Journal of Clinical Oncology. 36: 676-676. DOI: 10.1200/Jco.2018.36.4_Suppl.676  0.362
2017 Polireddy K, Dong R, Reed G, Yu J, Chen P, Williamson S, Violet PC, Pessetto Z, Godwin AK, Fan F, Levine M, Drisko JA, Chen Q. High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study. Scientific Reports. 7: 17188. PMID 29215048 DOI: 10.1038/s41598-017-17568-8  0.311
2017 Walker LC, Marquart L, Pearson JF, Wiggins GA, O'Mara TA, Parsons MT, Barrowdale D, McGuffog L, Dennis J, Benitez J, Slavin TP, Radice P, Frost D, ... Godwin AK, et al. Evaluation of copy-number variants as modifiers of breast and ovarian cancer risk for BRCA1 pathogenic variant carriers. European Journal of Human Genetics : Ejhg. PMID 28145423 DOI: 10.1038/Ejhg.2016.203  0.315
2016 Hamdi Y, Soucy P, Kuchenbaeker KB, Pastinen T, Droit A, Lemaçon A, Adlard J, Aittomäki K, Andrulis IL, Arason A, Arnold N, Arun BK, Azzollini J, Bane A, Barjhoux L, ... ... Godwin AK, et al. Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3. Breast Cancer Research and Treatment. PMID 27796716 DOI: 10.1007/S10549-016-4018-2  0.428
2016 Raghavan R, Hyter S, Pathak HB, Godwin AK, Konecny G, Wang C, Goode EL, Fridley BL. Drug discovery using clinical outcome-based Connectivity Mapping: application to ovarian cancer. Bmc Genomics. 17: 811. PMID 27756228 DOI: 10.1186/S12864-016-3149-5  0.312
2016 Peri S, Caretti E, Tricarico R, Devarajan K, Cheung M, Sementino E, Menges CW, Nicolas E, Vanderveer LA, Howard S, Conrad P, Crowell JA, Campbell KS, Ross EA, Godwin AK, et al. Haploinsufficiency in tumor predisposition syndromes: altered genomic transcription in morphologically normal cells heterozygous for VHL or TSC mutation. Oncotarget. PMID 27682873 DOI: 10.18632/Oncotarget.12192  0.325
2016 Vigorito E, Kuchenbaecker KB, Beesley J, Adlard J, Agnarsson BA, Andrulis IL, Arun BK, Barjhoux L, Belotti M, Benitez J, Berger A, Bojesen A, Bonanni B, Brewer C, Caldes T, ... ... Godwin AK, et al. Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers. Plos One. 11: e0158801. PMID 27463617 DOI: 10.1371/Journal.Pone.0158801  0.411
2016 Zeng C, Guo X, Long J, Kuchenbaecker KB, Droit A, Michailidou K, Ghoussaini M, Kar S, Freeman A, Hopper JL, Milne RL, Bolla MK, Wang Q, Dennis J, Agata S, ... ... Godwin AK, et al. Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus. Breast Cancer Research : Bcr. 18: 64. PMID 27459855 DOI: 10.1186/S13058-016-0718-0  0.347
2016 Wang Y, Cai KQ, Smith ER, Yeasky TM, Moore R, Ganjei-Azar P, Klein-Szanto AJ, Godwin AK, Hamilton TC, Xu XX. Follicle Depletion Provides A Permissive Environment for Ovarian Carcinogenesis. Molecular and Cellular Biology. PMID 27354067 DOI: 10.1128/Mcb.00202-16  0.661
2016 Couch FJ, Kuchenbaecker KB, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J, Olswold C, Hallberg E, Agata S, Ahsan H, Aittomäki K, Ambrosone C, Andrulis IL, Anton-Culver H, Arndt V, ... ... Godwin AK, et al. Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nature Communications. 7: 11375. PMID 27117709 DOI: 10.1038/Ncomms11375  0.38
2016 Silvestri V, Barrowdale D, Mulligan AM, Neuhausen SL, Fox S, Karlan BY, Mitchell G, James P, Thull DL, Zorn KK, Carter NJ, Nathanson KL, Domchek SM, Rebbeck TR, Ramus SJ, ... ... Godwin AK, et al. Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Research : Bcr. 18: 15. PMID 26857456 DOI: 10.1186/S13058-016-0671-Y  0.376
2015 Pathak HB, Zhou Y, Sethi G, Hirst J, Schilder RJ, Golemis EA, Godwin AK. A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer. Plos One. 10: e0144126. PMID 26637171 DOI: 10.1371/Journal.Pone.0144126  0.542
2015 Elsarraj HS, Hong Y, Valdez KE, Michaels W, Hook M, Smith WP, Chien J, Herschkowitz JI, Troester MA, Beck M, Inciardi M, Gatewood J, May L, Cusick T, McGinness M, ... ... Godwin AK, et al. Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion. Breast Cancer Research : Bcr. 17: 128. PMID 26384318 DOI: 10.1186/S13058-015-0630-Z  0.316
2015 Blanco I, Kuchenbaecker K, Cuadras D, Wang X, Barrowdale D, de Garibay GR, Librado P, Sánchez-Gracia A, Rozas J, Bonifaci N, McGuffog L, Pankratz VS, Islam A, Mateo F, Berenguer A, ... ... Godwin AK, et al. Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers. Plos One. 10: e0120020. PMID 25830658 DOI: 10.1371/Journal.Pone.0120020  0.386
2015 Kwon Y, Smith BD, Zhou Y, Kaufman MD, Godwin AK. Effective inhibition of c-MET-mediated signaling, growth and migration of ovarian cancer cells is influenced by the ovarian tissue microenvironment. Oncogene. 34: 144-53. PMID 24362531 DOI: 10.1038/Onc.2013.539  0.302
2014 Kuchenbaecker KB, Neuhausen SL, Robson M, Barrowdale D, McGuffog L, Mulligan AM, Andrulis IL, Spurdle AB, Schmidt MK, Schmutzler RK, Engel C, Wappenschmidt B, Nevanlinna H, Thomassen M, Southey M, ... ... Godwin AK, et al. Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research : Bcr. 16: 3416. PMID 25919761 DOI: 10.1186/S13058-014-0492-9  0.355
2014 Spurdle AB, Couch FJ, Parsons MT, McGuffog L, Barrowdale D, Bolla MK, Wang Q, Healey S, Schmutzler R, Wappenschmidt B, Rhiem K, Hahnen E, Engel C, Meindl A, Ditsch N, ... ... Godwin AK, et al. Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia. Breast Cancer Research : Bcr. 16: 3419. PMID 25857409 DOI: 10.1186/S13058-014-0474-Y  0.346
2014 Rudd ML, Mohamed H, Price JC, O'Hara AJ, Le Gallo M, Urick ME, Cruz P, Zhang S, Hansen NF, Godwin AK, Sgroi DC, Wolfsberg TG, Mullikin JC, Merino MJ, et al. Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1. Bmc Cancer. 14: 884. PMID 25427824 DOI: 10.1186/1471-2407-14-884  0.306
2014 Zhang X, Cheng L, Minn K, Madan R, Godwin AK, Shridhar V, Chien J. Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells. Oncotarget. 5: 11365-80. PMID 25426548  0.375
2014 Sethi G, Kwon Y, Burkhalter RJ, Pathak HB, Madan R, McHugh S, Atay S, Murthy S, Tawfik OW, Godwin AK. PTN signaling: Components and mechanistic insights in human ovarian cancer. Molecular Carcinogenesis. PMID 25418856 DOI: 10.1002/Mc.22249  0.634
2014 Huang CH, Wick JA, Sittampalam GS, Nirmalanandhan VS, Ganti AK, Neupane PC, Williamson SK, Godwin AK, Schmitt S, Smart NJ, Spencer S, Van Veldhuizen PJ. A multicenter pilot study examining the role of circulating tumor cells as a blood-based tumor marker in patients with extensive small-cell lung cancer. Frontiers in Oncology. 4: 271. PMID 25353007 DOI: 10.3389/fonc.2014.00271  0.301
2014 Sharma P, Stecklein SR, Kimler BF, Sethi G, Petroff BK, Phillips TA, Tawfik OW, Godwin AK, Jensen RA. The prognostic value of BRCA1 promoter methylation in early stage triple negative breast cancer. Journal of Cancer Therapeutics & Research. 3: 1-11. PMID 25177489 DOI: 10.7243/2049-7962-3-2  0.56
2014 Osorio A, Milne RL, Kuchenbaecker K, Vaclová T, Pita G, Alonso R, Peterlongo P, Blanco I, de la Hoya M, Duran M, Díez O, Ramón Y Cajal T, Konstantopoulou I, Martínez-Bouzas C, Andrés Conejero R, ... ... Godwin AK, et al. DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers. Plos Genetics. 10: e1004256. PMID 24698998 DOI: 10.1371/Journal.Pgen.1004256  0.303
2014 Atay S, Banskota S, Crow J, Sethi G, Rink L, Godwin AK. Oncogenic KIT-containing exosomes increase gastrointestinal stromal tumor cell invasion. Proceedings of the National Academy of Sciences of the United States of America. 111: 711-6. PMID 24379393 DOI: 10.1073/Pnas.1310501111  0.539
2014 Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC. Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion. Oncogene. 33: 539-49. PMID 23334327 DOI: 10.1038/Onc.2012.632  0.329
2013 Pessetto ZY, Weir SJ, Sethi G, Broward MA, Godwin AK. Drug repurposing for gastrointestinal stromal tumor. Molecular Cancer Therapeutics. 12: 1299-309. PMID 23657945 DOI: 10.1158/1535-7163.Mct-12-0968  0.499
2013 Couch FJ, Wang X, McGuffog L, Lee A, Olswold C, Kuchenbaecker KB, Soucy P, Fredericksen Z, Barrowdale D, Dennis J, Gaudet MM, Dicks E, Kosel M, Healey S, Sinilnikova OM, ... ... Godwin AK, et al. Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. Plos Genetics. 9: e1003212. PMID 23544013 DOI: 10.1371/Journal.Pgen.1003212  0.411
2013 Leslie KK, Sill MW, Fischer E, Darcy KM, Mannel RS, Tewari KS, Hanjani P, Wilken JA, Baron AT, Godwin AK, Schilder RJ, Singh M, Maihle NJ. A phase II evaluation of gefitinib in the treatment of persistent or recurrent endometrial cancer: a Gynecologic Oncology Group study. Gynecologic Oncology. 129: 486-94. PMID 23438670 DOI: 10.1016/J.Ygyno.2013.02.019  0.31
2013 Bernardo GM, Bebek G, Ginther CL, Sizemore ST, Lozada KL, Miedler JD, Anderson LA, Godwin AK, Abdul-Karim FW, Slamon DJ, Keri RA. FOXA1 represses the molecular phenotype of basal breast cancer cells. Oncogene. 32: 554-63. PMID 22391567 DOI: 10.1038/Onc.2012.62  0.354
2013 Yew K, Crow J, Hirst J, Pessetto Z, Godwin AK. Correction: Epimorphin-Induced MET Sensitizes Ovarian Cancer Cells to Platinum Plos One. 8. DOI: 10.1371/annotation/9c557fb1-7997-4c21-bd11-03bf5c3d4418  0.309
2012 Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. Plos One. 7: e47086. PMID 23056589 DOI: 10.1371/Journal.Pone.0047086  0.605
2012 Guo S, Liu M, Godwin AK. Transcriptional regulation of hTREX84 in human cancer cells. Plos One. 7: e43610. PMID 22952718 DOI: 10.1371/journal.pone.0043610  0.332
2012 Couch FJ, Gaudet MM, Antoniou AC, Ramus SJ, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, Wang X, Kirchhoff T, McGuffog L, Barrowdale D, Lee A, Healey S, Sinilnikova OM, ... ... Godwin AK, et al. Common variants at the 19p13.1 and ZNF365 loci are associated with ER subtypes of breast cancer and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 21: 645-57. PMID 22351618 DOI: 10.1158/1055-9965.Epi-11-0888  0.422
2012 Antoniou AC, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, McGuffog L, Lee A, Barrowdale D, Healey S, Sinilnikova OM, Caligo MA, Loman N, Harbst K, Lindblom A, Arver B, ... ... Godwin AK, et al. Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers. Breast Cancer Research : Bcr. 14: R33. PMID 22348646 DOI: 10.1186/Bcr3121  0.359
2012 Bolton KL, Chenevix-Trench G, Goh C, Sadetzki S, Ramus SJ, Karlan BY, Lambrechts D, Despierre E, Barrowdale D, McGuffog L, Healey S, Easton DF, Sinilnikova O, Benítez J, García MJ, ... ... Godwin AK, et al. Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer. Jama. 307: 382-90. PMID 22274685 DOI: 10.1001/Jama.2012.20  0.305
2012 Ramus SJ, Antoniou AC, Kuchenbaecker KB, Soucy P, Beesley J, Chen X, McGuffog L, Sinilnikova OM, Healey S, Barrowdale D, Lee A, Thomassen M, Gerdes AM, Kruse TA, Jensen UB, ... ... Godwin AK, et al. Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers. Human Mutation. 33: 690-702. PMID 22253144 DOI: 10.1002/Humu.22025  0.387
2012 Laitman Y, Kuchenbaecker KB, Rantala J, Hogervorst F, Peock S, Godwin AK, Arason A, Kirchhoff T, Offit K, Isaacs C, Schmutzler RK, Wappenschmidt B, Nevanlinna H, Chen X, Chenevix-Trench G, et al. The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment. 132: 1119-26. PMID 22212556 DOI: 10.1007/S10549-011-1938-8  0.319
2011 Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, ... ... Godwin AK, et al. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. Plos Biology. 9: e1001199. PMID 22110403 DOI: 10.1371/Journal.Pbio.1001199  0.304
2011 Mulligan AM, Couch FJ, Barrowdale D, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Robson M, Sherman M, Spurdle AB, Wappenschmidt B, Lee A, McGuffog L, Healey S, Sinilnikova OM, ... ... Godwin AK, et al. Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2. Breast Cancer Research : Bcr. 13: R110. PMID 22053997 DOI: 10.1186/Bcr3052  0.395
2011 Cox DG, Simard J, Sinnett D, Hamdi Y, Soucy P, Ouimet M, Barjhoux L, Verny-Pierre C, McGuffog L, Healey S, Szabo C, Greene MH, Mai PL, Andrulis IL, ... ... Godwin AK, et al. Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers. Human Molecular Genetics. 20: 4732-47. PMID 21890493 DOI: 10.1093/Hmg/Ddr388  0.411
2011 Bitler BG, Nicodemus JP, Li H, Cai Q, Wu H, Hua X, Li T, Birrer MJ, Godwin AK, Cairns P, Zhang R. Wnt5a suppresses epithelial ovarian cancer by promoting cellular senescence. Cancer Research. 71: 6184-94. PMID 21816908 DOI: 10.1158/0008-5472.Can-11-1341  0.349
2011 Behbakht K, Sill MW, Darcy KM, Rubin SC, Mannel RS, Waggoner S, Schilder RJ, Cai KQ, Godwin AK, Alpaugh RK. Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study. Gynecologic Oncology. 123: 19-26. PMID 21752435 DOI: 10.1016/J.Ygyno.2011.06.022  0.4
2011 Capo-chichi CD, Cai KQ, Smedberg J, Ganjei-Azar P, Godwin AK, Xu XX. Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer. Chinese Journal of Cancer. 30: 415-25. PMID 21627864 DOI: 10.5732/cjc.010.10566  0.327
2011 Sasaroli D, Gimotty PA, Pathak HB, Hammond R, Kougioumtzidou E, Katsaros D, Buckanovich R, Devarajan K, Sandaltzopoulos R, Godwin AK, Scholler N, Coukos G. Novel surface targets and serum biomarkers from the ovarian cancer vasculature. Cancer Biology & Therapy. 12: 169-80. PMID 21617380 DOI: 10.4161/Cbt.12.3.16260  0.406
2011 Antoniou AC, Kartsonaki C, Sinilnikova OM, Soucy P, McGuffog L, Healey S, Lee A, Peterlongo P, Manoukian S, Peissel B, Zaffaroni D, Cattaneo E, Barile M, Pensotti V, Pasini B, ... ... Godwin A, et al. Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics. 20: 3304-21. PMID 21593217 DOI: 10.1093/Hmg/Ddr226  0.383
2011 Huang J, Zhang L, Greshock J, Colligon TA, Wang Y, Ward R, Katsaros D, Lassus H, Butzow R, Godwin AK, Testa JR, Nathanson KL, Gimotty PA, Coukos G, Weber BL, et al. Frequent genetic abnormalities of the PI3K/AKT pathway in primary ovarian cancer predict patient outcome. Genes, Chromosomes & Cancer. 50: 606-18. PMID 21563232 DOI: 10.1002/Gcc.20883  0.364
2011 Kwon Y, Cukierman E, Godwin AK. Differential expressions of adhesive molecules and proteases define mechanisms of ovarian tumor cell matrix penetration/invasion. Plos One. 6: e18872. PMID 21526198 DOI: 10.1371/journal.pone.0018872  0.305
2011 Capo-chichi CD, Cai KQ, Simpkins F, Ganjei-Azar P, Godwin AK, Xu XX. Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer. Bmc Medicine. 9: 28. PMID 21439080 DOI: 10.1186/1741-7015-9-28  0.322
2011 Pharoah PD, Palmieri RT, Ramus SJ, Gayther SA, Andrulis IL, Anton-Culver H, Antonenkova N, Antoniou AC, Goldgar D, Beattie MS, Beckmann MW, Birrer MJ, Bogdanova N, Bolton KL, ... ... Godwin AK, et al. The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3742-50. PMID 21385923 DOI: 10.1158/1078-0432.Ccr-10-3405  0.387
2011 Arnold JN, Saldova R, Galligan MC, Murphy TB, Mimura-Kimura Y, Telford JE, Godwin AK, Rudd PM. Novel glycan biomarkers for the detection of lung cancer. Journal of Proteome Research. 10: 1755-64. PMID 21214223 DOI: 10.1021/Pr101034T  0.349
2011 Ramus SJ, Kartsonaki C, Gayther SA, Pharoah PD, Sinilnikova OM, Beesley J, Chen X, McGuffog L, Healey S, Couch FJ, Wang X, Fredericksen Z, Peterlongo P, Manoukian S, Peissel B, ... ... Godwin A, et al. Genetic variation at 9p22.2 and ovarian cancer risk for BRCA1 and BRCA2 mutation carriers. Journal of the National Cancer Institute. 103: 105-16. PMID 21169536 DOI: 10.1093/Jnci/Djq494  0.322
2011 Anderson KS, Sibani S, Wallstrom G, Qiu J, Mendoza EA, Raphael J, Hainsworth E, Montor WR, Wong J, Park JG, Lokko N, Logvinenko T, Ramachandran N, Godwin AK, Marks J, et al. Protein microarray signature of autoantibody biomarkers for the early detection of breast cancer. Journal of Proteome Research. 10: 85-96. PMID 20977275 DOI: 10.1021/Pr100686B  0.378
2011 Nitta RT, Del Vecchio CA, Chu AH, Mitra SS, Godwin AK, Wong AJ. The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis. Oncogene. 30: 234-44. PMID 20871632 DOI: 10.1038/Onc.2010.414  0.368
2011 Bitler BG, Nicodemus JP, Li H, Cai Q, Soring K, Birrer MJ, Connolly DC, Godwin AK, Cairns P, Wu H, Zhang R. Abstract 1230: Wnt5a-dependent induction of senescence suppresses epithelial ovarian cancer Cancer Research. 71: 1230-1230. DOI: 10.1158/1538-7445.Am2011-1230  0.465
2010 Antoniou AC, Beesley J, McGuffog L, Sinilnikova OM, Healey S, Neuhausen SL, Ding YC, Rebbeck TR, Weitzel JN, Lynch HT, Isaacs C, Ganz PA, Tomlinson G, Olopade OI, Couch FJ, ... ... Godwin AK, et al. Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction. Cancer Research. 70: 9742-54. PMID 21118973 DOI: 10.1158/0008-5472.Can-10-1907  0.377
2010 Li H, Cai Q, Godwin AK, Zhang R. Enhancer of zeste homolog 2 promotes the proliferation and invasion of epithelial ovarian cancer cells. Molecular Cancer Research : McR. 8: 1610-8. PMID 21115743 DOI: 10.1158/1541-7786.MCR-10-0398  0.331
2010 Gaudet MM, Kirchhoff T, Green T, Vijai J, Korn JM, Guiducci C, Segrè AV, McGee K, McGuffog L, Kartsonaki C, Morrison J, Healey S, Sinilnikova OM, Stoppa-Lyonnet D, Mazoyer S, ... ... Godwin AK, et al. Common genetic variants and modification of penetrance of BRCA2-associated breast cancer. Plos Genetics. 6: e1001183. PMID 21060860 DOI: 10.1371/Journal.Pgen.1001183  0.388
2010 Capo-Chichi CD, Smedberg JL, Rula M, Nicolas E, Yeung AT, Adamo RF, Frolov A, Godwin AK, Xu XX. Alteration of Differentiation Potentials by Modulating GATA Transcription Factors in Murine Embryonic Stem Cells. Stem Cells International. 2010: 602068. PMID 21048850 DOI: 10.4061/2010/602068  0.316
2010 Tan Y, Cheung M, Pei J, Menges CW, Godwin AK, Testa JR. Upregulation of DLX5 promotes ovarian cancer cell proliferation by enhancing IRS-2-AKT signaling. Cancer Research. 70: 9197-206. PMID 21045156 DOI: 10.1158/0008-5472.CAN-10-1568  0.399
2010 Engel C, Versmold B, Wappenschmidt B, Simard J, Easton DF, Peock S, Cook M, Oliver C, Frost D, Mayes R, Evans DG, Eeles R, Paterson J, Brewer C, ... ... Godwin AK, et al. Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 19: 2859-68. PMID 20978178 DOI: 10.1158/1055-9965.Epi-10-0517  0.418
2010 Goode EL, Chenevix-Trench G, Song H, Ramus SJ, Notaridou M, Lawrenson K, Widschwendter M, Vierkant RA, Larson MC, Kjaer SK, Birrer MJ, Berchuck A, Schildkraut J, Tomlinson I, Kiemeney LA, ... ... Godwin AK, et al. A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nature Genetics. 42: 874-9. PMID 20852632 DOI: 10.1038/Ng.668  0.388
2010 Antoniou AC, Wang X, Fredericksen ZS, McGuffog L, Tarrell R, Sinilnikova OM, Healey S, Morrison J, Kartsonaki C, Lesnick T, Ghoussaini M, Barrowdale D, Peock S, Cook M, ... ... Godwin AK, et al. A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nature Genetics. 42: 885-92. PMID 20852631 DOI: 10.1038/Ng.669  0.38
2010 Ratner E, Lu L, Boeke M, Barnett R, Nallur S, Chin LJ, Pelletier C, Blitzblau R, Tassi R, Paranjape T, Hui P, Godwin AK, Yu H, Risch H, Rutherford T, et al. A KRAS-variant in ovarian cancer acts as a genetic marker of cancer risk. Cancer Research. 70: 6509-15. PMID 20647319 DOI: 10.1158/0008-5472.Can-10-0689  0.302
2010 Bernardo GM, Lozada KL, Miedler JD, Harburg G, Hewitt SC, Mosley JD, Godwin AK, Korach KS, Visvader JE, Kaestner KH, Abdul-Karim FW, Montano MM, Keri RA. FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis. Development (Cambridge, England). 137: 2045-54. PMID 20501593 DOI: 10.1242/Dev.043299  0.422
2010 Choi YL, Bocanegra M, Kwon MJ, Shin YK, Nam SJ, Yang JH, Kao J, Godwin AK, Pollack JR. LYN is a mediator of epithelial-mesenchymal transition and a target of dasatinib in breast cancer. Cancer Research. 70: 2296-306. PMID 20215510 DOI: 10.1158/0008-5472.Can-09-3141  0.331
2010 Smith ER, Cai KQ, Smedberg JL, Ribeiro MM, Rula ME, Slater C, Godwin AK, Xu XX. Nuclear Entry of Activated MAPK Is Restricted in Primary Ovarian and Mammary Epithelial Cells Plos One. 5. PMID 20174585 DOI: 10.1371/Journal.Pone.0009295  0.365
2010 Kamat AA, Baldwin M, Urbauer D, Dang D, Han LY, Godwin A, Karlan BY, Simpson JL, Gershenson DM, Coleman RL, Bischoff FZ, Sood AK. Plasma cell-free DNA in ovarian cancer: an independent prognostic biomarker. Cancer. 116: 1918-25. PMID 20166213 DOI: 10.1002/Cncr.24997  0.365
2010 Corney DC, Hwang CI, Matoso A, Vogt M, Flesken-Nikitin A, Godwin AK, Kamat AA, Sood AK, Ellenson LH, Hermeking H, Nikitin AY. Frequent downregulation of miR-34 family in human ovarian cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 1119-28. PMID 20145172 DOI: 10.1158/1078-0432.Ccr-09-2642  0.326
2010 Bellacosa A, Godwin AK, Peri S, Devarajan K, Caretti E, Vanderveer L, Bove B, Slater C, Zhou Y, Daly M, Howard S, Campbell KS, Nicolas E, Yeung AT, Clapper ML, et al. Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutations. Cancer Prevention Research (Philadelphia, Pa.). 3: 48-61. PMID 20051372 DOI: 10.1158/1940-6207.Capr-09-0078  0.385
2010 Mehra R, Cai KQ, Zhu F, Weaver J, Nicolaou N, Cohen RB, Lango M, Ridge JA, Godwin AK, Burtness B. Analysis of ERCC1 (excision repair cross complementing group 1) in squamous cell carcinoma of the head and neck (SCCHN) by quantitative immunohistochemistry (IHC) using FL297. Journal of Clinical Oncology. 28: 5539-5539. DOI: 10.1200/Jco.2010.28.15_Suppl.5539  0.316
2010 Nitta RT, Chu A, Mitra S, Godwin A, Wong A. Abstract 310: The role of c-Jun N-terminal kinase 2alpha in non-small cell lung carcinoma tumorigenesis Cancer Research. 70: 310-310. DOI: 10.1158/1538-7445.Am10-310  0.39
2010 Mehra R, Cai KQ, Zhu F, Weaver J, Nicolaou N, Lango M, Ridge JA, Godwin AK, Burtness BA. Abstract 2804: ERCC1 (excision repair cross complementing group 1) is a predictive biomarker of survival in squamous cell carcinoma of the head and neck (SCCHN) Cancer Research. 70: 2804-2804. DOI: 10.1158/1538-7445.Am10-2804  0.363
2009 Ochs MF, Rink L, Tarn C, Mburu S, Taguchi T, Eisenberg B, Godwin AK. Detection of treatment-induced changes in signaling pathways in gastrointestinal stromal tumors using transcriptomic data Cancer Research. 69: 9125-9132. PMID 19903850 DOI: 10.1158/0008-5472.Can-09-1709  0.351
2009 Dupart JJ, Trent JC, Lee HY, Hess KR, Godwin AK, Taguchi T, Zhang W. Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro. Molecular Cancer. 8: 99. PMID 19903356 DOI: 10.1186/1476-4598-8-99  0.369
2009 Neuhausen SL, Brummel S, Ding YC, Singer CF, Pfeiler G, Lynch HT, Nathanson KL, Rebbeck TR, Garber JE, Couch F, Weitzel J, Narod SA, Ganz PA, Daly MB, Godwin AK, et al. Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers. Breast Cancer Research : Bcr. 11: R76. PMID 19843326 DOI: 10.1186/Bcr2414  0.397
2009 Rink L, Skorobogatko Y, Kossenkov AV, Belinsky MG, Pajak T, Heinrich MC, Blanke CD, von Mehren M, Ochs MF, Eisenberg B, Godwin AK. Gene expression signatures and response to imatinib mesylate in gastrointestinal stromal tumor. Molecular Cancer Therapeutics. 8: 2172-82. PMID 19671739 DOI: 10.1158/1535-7163.Mct-09-0193  0.35
2009 Antoniou AC, Sinilnikova OM, McGuffog L, Healey S, Nevanlinna H, Heikkinen T, Simard J, Spurdle AB, Beesley J, Chen X, Neuhausen SL, Ding YC, Couch FJ, Wang X, ... ... Godwin AK, et al. Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriers. Human Molecular Genetics. 18: 4442-56. PMID 19656774 DOI: 10.1093/Hmg/Ddp372  0.387
2009 Cai KQ, Caslini C, Capo-Chichi CD, Slater C, Smith ER, Wu H, Klein-Szanto AJ, Godwin AK, Xu XX. Loss of GATA4 and GATA6 expression specifies ovarian cancer histological subtypes and precedes neoplastic transformation of ovarian surface epithelia Plos One. 4. PMID 19649254 DOI: 10.1371/Journal.Pone.0006454  0.465
2009 Belinsky MG, Skorobogatko YV, Rink L, Pei J, Cai KQ, Vanderveer LA, Riddell D, Merkel E, Tarn C, Eisenberg BL, von Mehren M, Testa JR, Godwin AK. High density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumors. Genes, Chromosomes & Cancer. 48: 886-96. PMID 19585585 DOI: 10.1002/Gcc.20689  0.348
2009 Capo-chichi CD, Cai KQ, Testa JR, Godwin AK, Xu XX. Loss of GATA6 leads to nuclear deformation and aneuploidy in ovarian cancer Molecular and Cellular Biology. 29: 4766-4777. PMID 19581290 DOI: 10.1128/Mcb.00087-09  0.449
2009 Levina VV, Nolen B, Su Y, Godwin AK, Fishman D, Liu J, Mor G, Maxwell LG, Herberman RB, Szczepanski MJ, Szajnik ME, Gorelik E, Lokshin AE. Biological significance of prolactin in gynecologic cancers. Cancer Research. 69: 5226-33. PMID 19491263 DOI: 10.1158/0008-5472.Can-08-4652  0.46
2009 Kanetsky PA, Mitra N, Vardhanabhuti S, Li M, Vaughn DJ, Letrero R, Ciosek SL, Doody DR, Smith LM, Weaver J, Albano A, Chen C, Starr JR, Rader DJ, Godwin AK, et al. Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. Nature Genetics. 41: 811-5. PMID 19483682 DOI: 10.1038/Ng.393  0.326
2009 Wyman SK, Parkin RK, Mitchell PS, Fritz BR, O'Briant K, Godwin AK, Urban N, Drescher CW, Knudsen BS, Tewari M. Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. Plos One. 4: e5311. PMID 19390579 DOI: 10.1371/Journal.Pone.0005311  0.391
2009 Lynch HT, Casey MJ, Snyder CL, Bewtra C, Lynch JF, Butts M, Godwin AK. Hereditary ovarian carcinoma: heterogeneity, molecular genetics, pathology, and management. Molecular Oncology. 3: 97-137. PMID 19383374 DOI: 10.1016/J.Molonc.2009.02.004  0.42
2009 Howard JH, Frolov A, Tzeng CW, Stewart A, Midzak A, Majmundar A, Godwin A, Heslin M, Bellacosa A, Arnoletti JP. Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer. Cancer Biology & Therapy. 8: 94-100. PMID 19127118 DOI: 10.4161/Cbt.8.1.7469  0.388
2009 Johnatty SE, Couch FJ, Fredericksen Z, Tarrell R, Spurdle AB, Beesley J, Chen X, Gschwantler-Kaulich D, Singer CF, Fuerhauser C, Fink-Retter A, Domchek SM, ... ... Godwin AK, et al. No evidence that GATA3 rs570613 SNP modifies breast cancer risk. Breast Cancer Research and Treatment. 117: 371-9. PMID 19082709 DOI: 10.1007/S10549-008-0257-1  0.392
2009 Neuhausen SL, Ozcelik H, Southey MC, John EM, Godwin AK, Chung W, Iriondo-Perez J, Miron A, Santella RM, Whittemore A, Andrulis IL, Buys SS, Daly MB, Hopper JL, Seminara D, et al. BRCA1 and BRCA2 mutation carriers in the Breast Cancer Family Registry: an open resource for collaborative research. Breast Cancer Research and Treatment. 116: 379-86. PMID 18704680 DOI: 10.1007/S10549-008-0153-8  0.353
2009 Mehra R, Cai QK, Zhu F, Godwin A, Burtness B. Abstract A126: Analysis of excision repair cross complementing group 1 (ERCC1) expression in squamous cell carcinoma of the head and neck (SCCHN) Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A126  0.365
2009 Pape-Zambito D, Kistler J, Chen X, Li X, Chen Y, Cai K, Wu H, Huang M, Yeung A, Patchefsky A, Daly M, Godwin A. Molecular Biomarkers of Columnar Cell Lesions Identified by Proteomic Approaches. Cancer Research. 69: 2142-2142. DOI: 10.1158/0008-5472.Sabcs-09-2142  0.389
2008 Melnikov A, Scholtens D, Godwin A, Levenson V. Differential methylation profile of ovarian cancer in tissues and plasma. The Journal of Molecular Diagnostics : Jmd. 11: 60-65. PMID 19074590 DOI: 10.2353/Jmoldx.2009.080072  0.371
2008 Quiros RM, Valianou M, Kwon Y, Brown KM, Godwin AK, Cukierman E. Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner. Gynecologic Oncology. 110: 99-109. PMID 18448156 DOI: 10.1016/J.Ygyno.2008.03.006  0.358
2008 Antoniou AC, Spurdle AB, Sinilnikova OM, Healey S, Pooley KA, Schmutzler RK, Versmold B, Engel C, Meindl A, Arnold N, Hofmann W, Sutter C, Niederacher D, Deissler H, Caldes T, ... ... Godwin AK, et al. Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. American Journal of Human Genetics. 82: 937-48. PMID 18355772 DOI: 10.1016/J.Ajhg.2008.02.008  0.394
2008 Zecchini S, Bianchi M, Colombo N, Fasani R, Goisis G, Casadio C, Viale G, Liu J, Herlyn M, Godwin AK, Nuciforo PG, Cavallaro U. The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium Cancer Research. 68: 1110-1118. PMID 18281486 DOI: 10.1158/0008-5472.Can-07-2897  0.381
2008 Potapova A, Hoffman AM, Godwin AK, Al-Saleem T, Cairns P. Promoter hypermethylation of the PALB2 susceptibility gene in inherited and sporadic breast and ovarian cancer Cancer Research. 68: 998-1002. PMID 18281473 DOI: 10.1158/0008-5472.Can-07-2418  0.449
2008 Chen X, Weaver J, Bove BA, Vanderveer LA, Weil SC, Miron A, Daly MB, Godwin AK. Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk Human Molecular Genetics. 17: 1336-1348. PMID 18204050 DOI: 10.1093/hmg/ddn022  0.309
2008 Liang M, Ayanga B, Du S, Godwin AK, Hartsock JK, Evans SC. Ovca1, a candidate gene of the genetic modifier of Tp53, Mop2, affects mouse embryonic lethality Genes Chromosomes and Cancer. 47: 315-325. PMID 18181179 DOI: 10.1002/Gcc.20535  0.334
2007 Murph M, Tanaka T, Pang J, Felix E, Liu S, Trost R, Godwin AK, Newman R, Mills G. Liquid Chromatography Mass Spectrometry for Quantifying Plasma Lysophospholipids: Potential Biomarkers for Cancer Diagnosis Methods in Enzymology. 433: 1-25. PMID 17954226 DOI: 10.1016/S0076-6879(07)33001-2  0.453
2007 Giri VN, Beebe-Dimmer J, Buyyounouski M, Konski A, Feigenberg SJ, Uzzo RG, Hanks G, Godwin AK, Chen DY, Gordon R, Cescon T, Raysor S, Watkins-Bruner D. Prostate cancer risk assessment program: a 10-year update of cancer detection. The Journal of Urology. 178: 1920-4; discussion 1. PMID 17868726 DOI: 10.1016/J.Juro.2007.07.010  0.306
2007 Bell DW, Kim SH, Godwin AK, Schiripo TA, Harris PL, Haserlat SM, Wahrer DC, Haiman CA, Daly MB, Niendorf KB, Smith MR, Sgroi DC, Garber JE, Olopade OI, Le Marchand L, et al. Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts. International Journal of Cancer. Journal International Du Cancer. 121: 2661-7. PMID 17721994 DOI: 10.1002/Ijc.23026  0.416
2007 Couch FJ, Sinilnikova O, Vierkant RA, Pankratz VS, Fredericksen ZS, Stoppa-Lyonnet D, Coupier I, Hughes D, Hardouin A, Berthet P, Peock S, Cook M, Baynes C, Hodgson S, Morrison PJ, ... ... Godwin AK, et al. AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 1416-21. PMID 17627006 DOI: 10.1158/1055-9965.EPI-07-0129  0.3
2007 Tchou J, Ward MR, Volpe P, Palma MD, Medina CA, Sargen M, Sonnad SS, Godwin AK, Daly M, Winchester DJ, Garber J, Weber BL, Domchek S, Nathanson KL. Large genomic rearrangement in BRCA1 and BRCA2 and clinical characteristics of men with breast cancer in the United States. Clinical Breast Cancer. 7: 627-33. PMID 17592676 DOI: 10.3816/Cbc.2007.N.021  0.385
2007 Posadas EM, Liel MS, Kwitkowski V, Minasian L, Godwin AK, Hussain MM, Espina V, Wood BJ, Steinberg SM, Kohn EC. A phase II and pharmacodynamic study of gefitinib in patients with refractory or recurrent epithelial ovarian cancer. Cancer. 109: 1323-30. PMID 17330838 DOI: 10.1002/Cncr.22545  0.358
2007 Li H, Cherukuri P, Li N, Cowling V, Spinella M, Cole M, Godwin AK, Wells W, DiRenzo J. Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors. Cancer Research. 67: 501-10. PMID 17234757 DOI: 10.1158/0008-5472.Can-05-4571  0.436
2007 Cai KQ, Yang WL, Capo-Chichi CD, Vanderveer L, Wu H, Godwin AK, Xu XX. Prominent expression of metalloproteinases in early stages of ovarian tumorigenesis Molecular Carcinogenesis. 46: 130-143. PMID 17131304 DOI: 10.1002/Mc.20273  0.367
2006 Tarn C, Godwin AK. The molecular pathogenesis of gastrointestinal stromal tumors Clinical Colorectal Cancer. 6. PMID 17101067 DOI: 10.3816/Ccc.2006.S.002  0.331
2006 Petrocca F, Iliopoulos D, Qin HR, Nicoloso MS, Yendamuri S, Wojcik SE, Shimizu M, Di Leva G, Vecchione A, Trapasso F, Godwin AK, Negrini M, Calin GA, Croce CM. Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. Cancer Research. 66: 10287-91. PMID 17079447 DOI: 10.1158/0008-5472.Can-06-2289  0.512
2006 Haile RW, Thomas DC, McGuire V, Felberg A, John EM, Milne RL, Hopper JL, Jenkins MA, Levine AJ, Daly MM, Buys SS, Senie RT, Andrulis IL, Knight JA, Godwin AK, et al. BRCA1 and BRCA2 mutation carriers, oral contraceptive use, and breast cancer before age 50. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 1863-70. PMID 17021353 DOI: 10.1158/1055-9965.Epi-06-0258  0.372
2006 McGuire V, John EM, Felberg A, Haile RW, Boyd NF, Thomas DC, Jenkins MA, Milne RL, Daly MB, Ward J, Terry MB, Andrulis IL, Knight JA, Godwin AK, Giles GG, et al. No increased risk of breast cancer associated with alcohol consumption among carriers of BRCA1 and BRCA2 mutations ages <50 years. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 1565-7. PMID 16896052 DOI: 10.1158/1055-9965.Epi-06-0323  0.341
2006 Chen X, Arciero CA, Wang C, Broccoli D, Godwin AK. BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation. Cancer Research. 66: 5039-46. PMID 16707425 DOI: 10.1158/0008-5472.CAN-05-4194  0.316
2006 Cai KQ, Klein-Szanto A, Karthik D, Edelson M, Daly MB, Ozols RF, Lynch HT, Godwin AK, Xu XX. Age-dependent morphological alterations of human ovaries from populations with and without BRCA mutations. Gynecologic Oncology. 103: 719-28. PMID 16698071 DOI: 10.1016/J.Ygyno.2006.03.053  0.43
2006 He F, Fenner BJ, Godwin AK, Kwang J. White spot syndrome virus open reading frame 222 encodes a viral E3 ligase and mediates degradation of a host tumor suppressor via ubiquitination Journal of Virology. 80: 3884-3892. PMID 16571805 DOI: 10.1128/Jvi.80.8.3884-3892.2006  0.365
2006 Prowse AH, Manek S, Varma R, Liu J, Godwin AK, Maher ER, Tomlinson IPM, Kennedy SH. Molecular genetic evidence that endometriosis is a precursor of ovarian cancer International Journal of Cancer. 119: 556-562. PMID 16506222 DOI: 10.1002/Ijc.21845  0.395
2006 Chen X, Arciero CA, Godwin AK. BRCA1-asscociated complexes: New targets to overcome breast cancer radiation resistance Expert Review of Anticancer Therapy. 6: 187-196. PMID 16445371 DOI: 10.1586/14737140.6.2.187  0.401
2006 Spurdle AB, Antoniou AC, Kelemen L, Holland H, Peock S, Cook MR, Smith PL, Greene MH, Simard J, Plourde M, Southey MC, Godwin AK, Beck J, Miron A, Daly MB, et al. The AIB1 polyglutamine repeat does not modify breast cancer risk in BRCA1 and BRCA2 mutation carriers. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 15: 76-9. PMID 16434590 DOI: 10.1158/1055-9965.Epi-05-0709  0.437
2006 Pan Z, Bruening W, Godwin AK. Involvement of RHO GTPases and ERK in synuclein-γ enhanced cancer cell motility International Journal of Oncology. 29: 1201-1205. DOI: 10.3892/Ijo.29.5.1201  0.415
2005 Tarn C, Godwin AK. Molecular research directions in the management of gastrointestinal stromal tumors Current Treatment Options in Oncology. 6: 473-486. PMID 16242052 DOI: 10.1007/S11864-005-0026-X  0.342
2005 Capo-Chichi CD, Rula ME, Smedberg JL, Vanderveer L, Parmacek MS, Morrisey EE, Godwin AK, Xu XX. Perception of differentiation cues by GATA factors in primitive endoderm lineage determination of mouse embryonic stem cells. Developmental Biology. 286: 574-86. PMID 16162334 DOI: 10.1016/J.Ydbio.2005.07.037  0.305
2005 Yang WL, Roland IH, Godwin AK, Xu XX. Loss of TNF-α-regulated COX-2 expression in ovarian cancer cells Oncogene. 24: 7991-8002. PMID 16044148 DOI: 10.1038/Sj.Onc.1208943  0.418
2005 Nunez MI, Rosen DG, Ludes-Meyers JH, Abba MC, Kil H, Page R, Klein-Szanto AJ, Godwin AK, Liu J, Mills GB, Aldaz CM. WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome. Bmc Cancer. 5: 64. PMID 15982416 DOI: 10.1186/1471-2407-5-64  0.415
2005 Calin GA, Trapasso F, Shimizu M, Dumitru CD, Yendamuri S, Godwin AK, Ferracin M, Bernardi G, Chatterjee D, Baldassarre G, Rattan S, Alder H, Mabuchi H, Shiraishi T, Hansen LL, et al. Familial cancer associated with a polymorphism in ARLTS1. The New England Journal of Medicine. 352: 1667-76. PMID 15843669 DOI: 10.1056/Nejmoa042280  0.378
2005 Guo S, Hakimi MA, Baillat D, Chen X, Farber MJ, Klein-Szanto AJ, Cooch NS, Godwin AK, Shiekhattar R. Linking transcriptional elongation and messenger RNA export to metastatic breast cancers. Cancer Research. 65: 3011-6. PMID 15833825 DOI: 10.1158/0008-5472.Can-04-3624  0.421
2005 Sarti M, Sevignani C, Calin GA, Aqeilan R, Shimizu M, Pentimalli F, Picchio MC, Godwin A, Rosenberg A, Drusco A, Negrini M, Croce CM. Adenoviral transduction of TESTIN gene into breast and uterine cancer cell lines promotes apoptosis and tumor reduction in vivo. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 806-13. PMID 15701871  0.323
2004 Stoyanova R, Clapper ML, Bellacosa A, Henske EP, Testa JR, Ross EA, Yeung AT, Nicolas E, Tsichlis N, Li YS, Linehan WM, Howard S, Campbell KS, Godwin AK, Boman BM, et al. Altered gene expression in phenotypically normal renal cells from carriers of tumor suppressor gene mutations. Cancer Biology & Therapy. 3: 1313-21. PMID 15662135 DOI: 10.4161/Cbt.3.12.1459  0.408
2004 Altomare DA, Hui QW, Skele KL, De Rienzo A, Klein-Szanto AJ, Godwin AK, Testa JR. AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth Oncogene. 23: 5853-5857. PMID 15208673 DOI: 10.1038/sj.onc.1207721  0.33
2004 Pinte S, Guérardel C, Deltour-Balerdi S, Godwin AK, Leprince D. Identification of a second G-C-rich promoter conserved in the human, murine and rat tumor suppressor genes HIC1 Oncogene. 23: 4023-4031. PMID 15007385 DOI: 10.1038/Sj.Onc.1207504  0.348
2004 Yang WL, Godwin AK, Xu XX. Tumor Necrosis Factor-α-Induced Matrix Proteolytic Enzyme Production and Basement Membrane Remodeling by Human Ovarian Surface Epithelial Cells: Molecular Basis Linking Ovulation and Cancer Risk Cancer Research. 64: 1534-1540. PMID 14973065 DOI: 10.1158/0008-5472.Can-03-2928  0.353
2004 Ozols RF, Bookman MA, Connolly DC, Daly MB, Godwin AK, Schilder RJ, Xu X, Hamilton TC. Focus on epithelial ovarian cancer Cancer Cell. 5: 19-24. PMID 14749123 DOI: 10.1016/S1535-6108(04)00002-9  0.615
2003 Roland IH, Yang WL, Yang DH, Daly MB, Ozols RF, Hamilton TC, Lynch HT, Godwin AK, Xu XX. Loss of surface and cyst epithelial basement membranes and preneoplastic morphologic changes in prophylactic oophorectomies. Cancer. 98: 2607-23. PMID 14669280 DOI: 10.1002/Cncr.11847  0.577
2003 Burrows JF, Chanduloy S, McIlhatton MA, Nagar H, Yeates K, Donaghy P, Price J, Godwin AK, Johnston PG, Russell SE. Altered expression of the septin gene, SEPT9, in ovarian neoplasia. The Journal of Pathology. 201: 581-8. PMID 14648661 DOI: 10.1002/Path.1484  0.403
2003 Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Molecular Cell. 12: 1087-99. PMID 14636569 DOI: 10.1016/S1097-2765(03)00424-6  0.3
2003 Capo-chichi CD, Roland IH, Vanderveer L, Bao R, Yamagata T, Hirai H, Cohen C, Hamilton TC, Godwin AK, Xu XX. Anomalous expression of epithelial differentiation-determining GATA factors in ovarian tumorigenesis. Cancer Research. 63: 4967-77. PMID 12941822  0.611
2003 Prowse AH, Schultz DC, Guo S, Vanderveer L, Dangel J, Bove B, Cairns P, Daly M, Godwin AK. Identification of a splice acceptor site mutation in p16INK4A/p14ARF within a breast cancer, melanoma, neurofibroma prone kindred. Journal of Medical Genetics. 40: e102. PMID 12920094 DOI: 10.1136/Jmg.40.8.E102  0.436
2003 Cesari R, Martin ES, Calin GA, Pentimalli F, Bichi R, McAdams H, Trapasso F, Drusco A, Shimizu M, Masciullo V, D'Andrilli G, Scambia G, Picchio MC, Alder H, Godwin AK, et al. Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27 Proceedings of the National Academy of Sciences of the United States of America. 100: 5956-5961. PMID 12719539 DOI: 10.1073/Pnas.0931262100  0.39
2003 Okamoto I, Kenyon LC, Emlet DR, Mori T, Sasaki J, Hirosako S, Ichikawa Y, Kishi H, Godwin AK, Yoshioka M, Suga M, Matsumoto M, Wong AJ. Expression of constitutively activated EGFRvIII in non-small cell lung cancer. Cancer Science. 94: 50-6. PMID 12708474 DOI: 10.1111/J.1349-7006.2003.Tb01351.X  0.342
2003 Gupta A, Godwin AK, Vanderveer L, Lu A, Liu J. Hypomethylation of the Synuclein γ gene CpG island promotes its aberrant expression in breast carcinoma and ovarian carcinoma Cancer Research. 63: 664-673. PMID 12566312  0.351
2003 Ochs MF, Godwin AK. Microarrays in Cancer: Research and Applications Biotechniques. 34: S4-S15. DOI: 10.2144/Mar03Ochs  0.327
2003 Frolov AE, Godwin AK, Favorova OO. Differential gene expression analysis by DNA microarrays technology and its application in molecular oncology Molekulyarnaya Biologiya. 37: 573-584. DOI: 10.1023/A:1025166706481  0.427
2003 Okamoto I, Kenyon LC, Emlet DR, Godwin AK, Mori T, Yoshioka M, Sasaki J, Suga M, Matsumoto M, Wong AJ. P-134 Expression of constitutively activated EGFRvIII in non-small cell lung cancer Lung Cancer. 41: S124. DOI: 10.1016/S0169-5002(03)92103-9  0.354
2002 Capo-Chichi CD, Smith ER, Yang DH, Roland IH, Vanderveer L, Cohen C, Hamilton TC, Godwin AK, Xu XX. Dynamic alterations of the extracellular environment of ovarian surface epithelial cells in premalignant transformation, tumorigenicity, and metastasis. Cancer. 95: 1802-15. PMID 12365030 DOI: 10.1002/Cncr.10870  0.631
2002 Frolov A, Prowse AH, Vanderveer L, Bove B, Wu H, Godwin AK. DNA array-based method for detection of large rearrangements in the BRCA1 gene Genes Chromosomes and Cancer. 35: 232-241. PMID 12353265 DOI: 10.1002/Gcc.10109  0.434
2002 Smedberg JL, Smith ER, Capo-chichi CD, Frolov A, Yang DH, Godwin AK, Xu XX, Pa. Ras/MAPK pathway confers basement membrane dependence upon endoderm differentiation of embryonic carcinoma cells Journal of Biological Chemistry. 277: 40911-40918. PMID 12145292 DOI: 10.1074/Jbc.M205178200  0.315
2002 Antonyak MA, Kenyon LC, Godwin AK, James DC, Emlet DR, Okamoto I, Tnani M, Holgado-Madruga M, Moscatello DK, Wong AJ. Elevated JNK activation contributes to the pathogenesis of human brain tumors. Oncogene. 21: 5038-46. PMID 12140754 DOI: 10.1038/Sj.Onc.1205593  0.364
2002 Andrulis IL, Anton-Culver H, Beck J, Bove B, Boyd J, Buys S, Godwin AK, Hopper JL, Li F, Neuhausen SL, Ozcelik H, Peel D, Santella RM, Southey MC, van Orsouw NJ, et al. Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations. Human Mutation. 20: 65-73. PMID 12112659 DOI: 10.1002/Humu.10097  0.312
2002 Yang DH, Smith ER, Cohen C, Wu H, Patriotis C, Godwin AK, Hamilton TC, Xu XX. Molecular events associated with dysplastic morphologic transformation and initiation of ovarian tumorigenicity Cancer. 94: 2380-2392. PMID 12015763 DOI: 10.1002/Cncr.10497  0.648
2002 Prowse AH, Vanderveer L, Milling SW, Pan ZZ, Dunbrack RL, Xu XX, Godwin AK. OVCA2 is downregulated and degraded during retinoid-induced apoptosis. International Journal of Cancer. Journal International Du Cancer. 99: 185-92. PMID 11979432 DOI: 10.1002/Ijc.10334  0.384
2002 Broccoli D, Godwin AK. Telomere length changes in human cancer. Methods in Molecular Medicine. 68: 271-8. PMID 11901508 DOI: 10.1385/1-59259-135-3:271  0.344
2002 Roberts D, Williams SJ, Cvetkovic D, Weinstein JK, Godwin AK, Johnson SW, Hamilton TC. Decreased expression of retinol-binding proteins is associated with malignant transformation of the ovarian surface epithelium. Dna and Cell Biology. 21: 11-9. PMID 11879576 DOI: 10.1089/10445490252810276  0.637
2002 Okamoto I, Tsuiki H, Kenyon LC, Godwin AK, Emlet DR, Holgado-Madruga M, Lanham IS, Joynes CJ, Vo KT, Guha A, Matsumoto M, Ushio Y, Saya H, Wong AJ. Proteolytic cleavage of the CD44 adhesion molecule in multiple human tumors. The American Journal of Pathology. 160: 441-7. PMID 11839564 DOI: 10.1016/S0002-9440(10)64863-8  0.307
2001 Runnebaum IB, Wang-Gohrke S, Vesprini D, Kreienberg R, Lynch H, Moslehi R, Ghadirian P, Weber B, Godwin AK, Risch H, Garber J, Lerman C, Olopade OI, Foulkes WD, Karlan B, et al. Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptives. Pharmacogenetics. 11: 635-8. PMID 11668223 DOI: 10.1097/00008571-200110000-00010  0.321
2001 Smith ER, Capo-chichi CD, He J, Smedberg JL, Yang DH, Prowse AH, Godwin AK, Hamilton TC, Xu XX. Disabled-2 mediates c-Fos suppression and the cell growth regulatory activity of retinoic acid in embryonic carcinoma cells. The Journal of Biological Chemistry. 276: 47303-10. PMID 11577091 DOI: 10.1074/Jbc.M106158200  0.584
2001 Guerardel C, Deltour S, Pinte S, Monte D, Begue A, Godwin AK, Leprince D. Identification in the Human Candidate Tumor Suppressor Gene HIC-1 of a New Major Alternative TATA-less Promoter Positively Regulated by p53 Journal of Biological Chemistry. 276: 3078-3089. PMID 11073960 DOI: 10.1074/Jbc.M008690200  0.364
2000 Salicioni AM, Xi M, Vanderveer LA, Balsara B, Testa JR, Dunbrack RL, Godwin AK. Identification and structural analysis of human RBM8A and RBM8B: Two highly conserved RNA-binding motif proteins that interact with OVCA1, a candidate tumor suppressor Genomics. 69: 54-62. PMID 11013075 DOI: 10.1006/Geno.2000.6315  0.31
2000 Bruening W, Giasson BI, Klein-Szanto AJ, Lee VM, Trojanowski JQ, Godwin AK. Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary. Cancer. 88: 2154-63. PMID 10813729 DOI: 10.1002/(Sici)1097-0142(20000501)88:9<2154::Aid-Cncr23>3.0.Co;2-9  0.341
1999 Dangel J, Wagner-Costalas J, Bove B, Vanderveer L, Itzen M, Daly M, Godwin AK. Novel germline BRCA1 mutation (155del4) in an African American with early-onset breast cancer Human Mutation. 14: 545. PMID 10571958 DOI: 10.1002/(Sici)1098-1004(199912)14:6<545::Aid-Humu19>3.0.Co;2-G  0.371
1999 Bruening W, Prowse AH, Schultz DC, Holgado-Madruga M, Wong A, Godwin AK. Expression of OVCA1, a candidate tumor suppressor, is reduced in tumors and inhibits growth of ovarian cancer cells Cancer Research. 59: 4973-4983. PMID 10519411  0.359
1999 Wang-Gohrke S, Weikel W, Risch H, Vesprini D, Abrahamson J, Lerman C, Godwin A, Moslehi R, Olipade O, Brunet JS, Stickeler E, Kieback DG, Kreienberg R, Weber B, Narod SA, et al. Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations. British Journal of Cancer. 81: 179-83. PMID 10487631 DOI: 10.1038/sj.bjc.6690669  0.318
1999 Kruk PA, Godwin AK, Hamilton TC, Auersperg N. Telomeric instability and reduced proliferative potential in ovarian surface epithelial cells from women with a family history of ovarian cancer Gynecologic Oncology. 73: 229-236. PMID 10329039 DOI: 10.1006/Gyno.1999.5348  0.664
1999 Rebbeck TR, Kantoff PW, Krithivas K, Neuhausen S, Blackwood MA, Godwin AK, Daly MB, Narod SA, Garber JE, Lynch HT, Weber BL, Brown M. Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat. American Journal of Human Genetics. 64: 1371-7. PMID 10205268 DOI: 10.1086/302366  0.4
1999 Abdollahi A, Getts LA, Sonoda G, Miller PD, Taguchi T, Godwin AK, Testa JR, Hamilton TC. Genome Scanning Detects Amplification of the Cathepsin B Gene (CtsB) in Transformed Rat Ovarian Surface Epithelial Cells Journal of the Society For Gynecologic Investigation. 6: 32-40. DOI: 10.1177/107155769900600108  0.556
1998 Redston M, Nathanson KL, Yuan ZQ, Neuhausen SL, Satagopan J, Wong N, Yang D, Nafa D, Abrahamson J, Ozcelik H, Antin-Ozerkis D, Andrulis I, Daly M, Pinsky L, Schrag D, ... ... Godwin A, et al. The APCI1307K allele and breast cancer risk. Nature Genetics. 20: 13-4. PMID 9731522 DOI: 10.1038/1666  0.367
1998 Lynch HT, Casey MJ, Lynch J, White TEK, Godwin AK. Genetics and ovarian carcinoma Seminars in Oncology. 25: 265-280. PMID 9633840  0.386
1998 Hamilton TC, Johnson SW, Godwin AK. Molecular biology of gynecologic malignancies. Cancer Treatment and Research. 95: 103-14. PMID 9619281 DOI: 10.1007/978-1-4615-5447-9_2  0.625
1998 Brunet JS, Ghadirian P, Rebbeck TR, Lerman C, Garber JE, Tonin PN, Abrahamson J, Foulkes WD, Daly M, Wagner-Costalas J, Godwin A, Olopade OI, Moslehi R, Liede A, Futreal PA, et al. Effect of smoking on breast cancer in carriers of mutant BRCA1 or BRCA2 genes. Journal of the National Cancer Institute. 90: 761-6. PMID 9605646 DOI: 10.1093/Jnci/90.10.761  0.371
1997 Monaco C, Negrini M, Sozzi G, Veronese ML, Vorechovsky I, Godwin AK, Croce M C. Molecular cloning and characterization of LOH11CR2A, a new gene within a refined minimal region of LOH at 11q23 Genomics. 46: 217-222. PMID 9417908 DOI: 10.1006/Geno.1997.5036  0.357
1997 Sonoda G, Palazzo J, du Manoir S, Godwin AK, Feder M, Yakushiji M, Testa JR. Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24, and 20q13 in human ovarian carcinomas. Genes, Chromosomes & Cancer. 20: 320-8. PMID 9408747 DOI: 10.1002/(Sici)1098-2264(199712)20:4<320::Aid-Gcc2>3.0.Co;2-3  0.304
1997 Petrukhin L, Dangel J, Vanderveer L, Costalas J, Bellacosa A, Grana G, Daly M, Godwin AK. The I1307K APC mutation does not predispose to colorectal cancer in Jewish Ashkenazi breast and breast-ovarian cancer kindreds Cancer Research. 57: 5480-5484. PMID 9407954  0.318
1997 Abdollahi A, Roberts D, Godwin AK, Schultz DC, Sonoda G, Testa JR, Hamilton TC. Identification of a zinc-finger gene at 6q25: A chromosomal region implicated in development of many solid tumors Oncogene. 14: 1973-1979. PMID 9150364 DOI: 10.1038/Sj.Onc.1201034  0.644
1997 Sonoda G, Du Manoir S, Godwin AK, Bell DW, Liu Z, Hogan M, Yakushiji M, Testa JR. Detection of DNA gains and losses in primary endometrial carcinomas by comparative genomic hybridization Genes Chromosomes and Cancer. 18: 115-125. PMID 9115961 DOI: 10.1002/(Sici)1098-2264(199702)18:2<115::Aid-Gcc6>3.0.Co;2-5  0.329
1996 Dyck HG, Hamilton TC, Godwin AK, Lynch HT, Maines-Bandiera S, Auersperg N. Autonomy of the epithelial phenotype in human ovarian surface epithelium: Changes with neoplastic progression and with a family history of ovarian cancer International Journal of Cancer. 69: 429-436. PMID 8980241 DOI: 10.1002/(Sici)1097-0215(19961220)69:6<429::Aid-Ijc1>3.0.Co;2-6  0.658
1996 Salazar H, Godwin AK, Daly MB, Laub PB, Hogan WM, Rosenblum N, Boente MP, Lynch HT, Hamilton TC. Microscopic benign and invasive malignant neoplasms and a cancer-prone phenotype in prophylactic oophorectomies. Journal of the National Cancer Institute. 88: 1810-20. PMID 8961970 DOI: 10.1093/Jnci/88.24.1810  0.638
1996 Rebbeck TR, Godwin AK, Buetow KH. Variability in loss of constitutional heterozygosity across loci and among individuals: Association with candidate genes in ductal breast carcinoma Molecular Carcinogenesis. 17: 117-125. PMID 8944071 DOI: 10.1002/(Sici)1098-2744(199611)17:3<117::Aid-Mc3>3.0.Co;2-C  0.357
1996 Berman DB, Costalas J, Schultz DC, Grana G, Daly M, Godwin AK. A common mutation in BRCA2 that predisposes to a variety of cancers is found in both Jewish Ashkenazi and non-Jewish individuals. Cancer Research. 56: 3409-14. PMID 8758903  0.333
1996 Boente MP, Hamilton TC, Godwin AK, Buetow K, Kohler MF, Hogan WM, Berchuck A, Young RC. Early ovarian cancer: a review of its genetic and biologic factors, detection, and treatment. Current Problems in Cancer. 20: 83-137. PMID 8731031  0.542
1996 O'Dwyer PJ, Perez RP, Yao KS, Godwin AK, Hamilton TC. Increased DT-diaphorase expression and cross-resistance to mitomycin C in a series of cisplatin-resistant human ovarian cancer cell lines Biochemical Pharmacology. 52: 21-27. PMID 8678904 DOI: 10.1016/0006-2952(96)00131-1  0.575
1996 Schultz DC, Vanderveer L, Berman DB, Hamilton TC, Wong AJ, Godwin AK. Identification of two candidate tumor suppressor genes on chromosome 17p13.3. Cancer Research. 56: 1997-2002. PMID 8616839  0.303
1996 Schröder CP, Godwin AK, O'Dwyer PJ, Tew KD, Hamilton TC, Ozols RF. Glutathione and drug resistance Cancer Investigation. 14: 158-168. PMID 8597901 DOI: 10.3109/07357909609018891  0.513
1995 Schultz DC, Vanderveer L, Ozols RF, Hamilton TC, Godwin AK, Buetow KH, Boente MP. Characterization of Chromosome 9 in Human Ovarian Neoplasia Identifies Frequent Genetic Imbalance on 9q and Rare Alterations Involving 9p, Including CDKN2 Cancer Research. 55: 2150-2157. PMID 7743516  0.34
1995 Godwin AK, Miller PD, Getts LA, Jackson K, Sonoda G, Schray KJ, Testa JR, Hamilton TC. Retroviral-like sequences specifically expressed in the rat ovary detect genetic differences between normal and transformed rat ovarian surface epithelial cells. Endocrinology. 136: 4640-9. PMID 7664684 DOI: 10.1210/Endo.136.10.7664684  0.59
1995 Bellacosa A, de Feo D, Godwin AK, Bell DW, Cheng JQ, Altomare DA, Wan M, Dubeau L, Scambia G, Masciullo V, Ferrandina G, Benedetti Panici P, Mancuso S, Neri G, Testa JR. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. International Journal of Cancer. 64: 280-5. PMID 7657393 DOI: 10.1002/Ijc.2910640412  0.358
1995 Auersperg N, Maines-Bandiera S, Booth JH, Lynch HT, Godwin AK, Hamilton TC. Expression of two mucin antigens in cultured human ovarian surface epithelium: Influence of a family history of ovarian cancer American Journal of Obstetrics and Gynecology. 173: 558-565. PMID 7645635 DOI: 10.1016/0002-9378(95)90282-1  0.615
1995 Kruh GD, Gaughan KT, Godwin A, Chan A. Expression pattern of MRP in human tissues and adult solid tumor cell lines Journal of the National Cancer Institute. 87: 1256-1258. PMID 7563173 DOI: 10.1093/Jnci/87.16.1256  0.34
1994 Testa JR, Getts LA, Salazar H, Liu Z, Handel LM, Godwin AK, Hamilton TC. Spontaneous transformation of rat ovarian surface epithelial cells results in well to poorly differentiated tumors with a parallel range of cytogenetic complexity. Cancer Research. 54: 2778-84. PMID 8168110  0.306
1994 Johnson SW, Perez RP, Godwin AK, Yeung AT, Handel LM, Ozols RF, Hamilton TC. Role of platinum-DNA adduct formation and removal in cisplatin resistance in human ovarian cancer cell lines Biochemical Pharmacology. 47: 689-697. PMID 8129746 DOI: 10.1016/0006-2952(94)90132-5  0.544
1993 Godwin AK, Testa JR, Hamilton TC. The biology of ovarian cancer development Cancer. 71: 530-536. PMID 8420673 DOI: 10.1002/Cncr.2820710207  0.665
1993 Perez RP, Godwin AK, Handel LM, Hamilton TC. A comparison of clonogenic, microtetrazolium and sulforhodamine B assays for determination of cisplatin cytotoxicity in human ovarian carcinoma cell lines European Journal of Cancer. 29: 395-399. PMID 8398340 DOI: 10.1016/0959-8049(93)90394-U  0.585
1992 Godwin AK, Testa JR, Handel LM, Liu Z, Vanderveer LA, Tracey PA, Hamilton TC. Spontaneous transformation of rat ovarian surface epithelial cells: Association with cytogenetic changes and implications of repeated ovulation in the etiology of ovarian cancer Journal of the National Cancer Institute. 84: 592-601. PMID 1556770 DOI: 10.1093/Jnci/84.8.592  0.658
1992 Godwin AK, Perez RP, Johnson SW, Hamaguchi K, Hamilton TC. Growth regulation of ovarian cancer Hematology/Oncology Clinics of North America. 6: 829-841. PMID 1500388 DOI: 10.1016/S0889-8588(18)30312-5  0.648
1992 Cheng JQ, Godwin AK, Bellacosa A, Taguchi T, Franke TF, Hamilton TC, Tsichlis PN, Testa JR. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas Proceedings of the National Academy of Sciences of the United States of America. 89: 9267-9271. PMID 1409633 DOI: 10.1073/Pnas.89.19.9267  0.546
1992 Godwin AK, Meister A, O'Dwyer PJ, Huang CS, Hamilton TC, Anderson ME. High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis Proceedings of the National Academy of Sciences of the United States of America. 89: 3070-3074. PMID 1348364 DOI: 10.1073/Pnas.89.7.3070  0.576
1988 Seyama T, Godwin AK, DiPietro M, Winokur TS, Lebovitz RM, Lieberman MW. In vitro and in vivo regulation of liver epithelial cells carrying a metallothionein-rasT24 fusion gene. Molecular Carcinogenesis. 1: 89-95. PMID 3076453 DOI: 10.1002/Mc.2940010204  0.359
1988 Li YC, Seyama T, Godwin AK, Winokur TS, Lebovitz RM, Lieberman MW. MTrasT24, a metallothionein-ras fusion gene, modulates expression in cultured rat liver cells of two genes associated with in vivo liver cancer. Proceedings of the National Academy of Sciences of the United States of America. 85: 344-8. PMID 2893374 DOI: 10.1073/Pnas.85.2.344  0.304
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