Rory P. Remmel - Publications

Affiliations: 
Medicinal Chemistry University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmaceutical Chemistry, Pharmacology
Website:
https://www.pharmacy.umn.edu/bio/cop-experts/rory-remmel

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mohamed ME, Schladt DP, Guan W, Wu B, van Setten J, Keating B, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Oetting WS, Jacobson PA. Tacrolimus Troughs and Genetic Determinants of Metabolism in Kidney Transplant Recipients: A comparison of four ancestry groups. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30953600 DOI: 10.1111/Ajt.15385  0.32
2018 Roslawski MJ, Remmel RP, Karanam A, Leppik IE, Marino SE, Birnbaum AK. Simultaneous quantification of thirteen cannabinoids and metabolites in human plasma by liquid chromatography tandem mass spectrometry in adult epilepsy patients. Therapeutic Drug Monitoring. PMID 30520828 DOI: 10.1097/Ftd.0000000000000583  0.327
2018 Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK. Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing. The Pharmacogenomics Journal. PMID 30442921 DOI: 10.1038/S41397-018-0063-Z  0.308
2018 Scheibner A, Remmel R, Schladt D, Oetting W, Guan W, Wu B, Dorr C, Israni A, Jacobson PA. Tacrolimus Elimination in Four Patients with a CYP3A5*3/*3 CYP3A4*22/*22 Genotype. Pharmacotherapy. PMID 29804290 DOI: 10.1002/Phar.2131  0.357
2017 Oetting WS, Wu B, Schladt DP, Guan W, Remmel RP, Mannon RB, Matas AJ, Israni AK, Jacobson PA. Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients. The Pharmacogenomics Journal. PMID 29160300 DOI: 10.1038/Tpj.2017.49  0.32
2017 Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity B, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. CRISPR/Cas9 genetic modification of CYP3A5 *3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28533324 DOI: 10.1124/Dmd.117.076307  0.321
2016 Dawadi S, Kawamura S, Rubenstein A, Remmel R, Aldrich CC. Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry. PMID 26875934 DOI: 10.1016/J.Bmc.2016.02.002  0.351
2015 Sanghavi K, Brundage RC, Miller MB, Schladt DP, Israni AK, Guan W, Oetting WS, Mannon RB, Remmel RP, Matas AJ, Jacobson PA. Genotype-guided tacrolimus dosing in African-American kidney transplant recipients. The Pharmacogenomics Journal. PMID 26667830 DOI: 10.1038/Tpj.2015.87  0.358
2015 Oetting WS, Schladt DP, Guan W, Miller MB, Remmel RP, Dorr C, Sanghavi K, Mannon RB, Herrera B, Matas AJ, Salomon DR, Kwok PY, Keating BJ, Israni AK, Jacobson PA, et al. Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26485092 DOI: 10.1111/Ajt.13495  0.305
2015 Polepally AR, Remmel RP, Brundage RC, Leppik IE, Rarick JO, Ramsay RE, Birnbaum AK. Steady-state pharmacokinetics and bioavailability of immediate-release and extended-release formulations of lamotrigine in elderly epilepsy patients: Use of stable isotope methodology. Journal of Clinical Pharmacology. 55: 1101-8. PMID 25903807 DOI: 10.1002/Jcph.522  0.305
2014 Conway JM, Birnbaum AK, Leppik IE, Pennell PB, White JR, Rarick JO, Remmel RP. Safety of an intravenous formulation of lamotrigine. Seizure. 23: 390-2. PMID 24560492 DOI: 10.1016/J.Seizure.2014.01.019  0.301
2014 Kumar A, Mann HJ, Remmel RP, Beilman GJ, Kaila N. Pharmacokinetic study in pigs and in vitro metabolic characterization in pig- and human-liver microsomes reveal marked differences in disposition and metabolism of tiletamine and zolazepam (Telazol). Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 44: 379-90. PMID 24020890 DOI: 10.3109/00498254.2013.833362  0.423
2013 Teitelbaum AM, Meissner A, Harding RA, Wong CA, Aldrich CC, Remmel RP. Synthesis, pH-dependent, and plasma stability of meropenem prodrugs for potential use against drug-resistant tuberculosis. Bioorganic & Medicinal Chemistry. 21: 5605-17. PMID 23845282 DOI: 10.1016/J.Bmc.2013.05.024  0.706
2013 Jones JM, Raleigh MD, Pentel PR, Harmon TM, Keyler DE, Remmel RP, Birnbaum AK. Stability of heroin, 6-monoacetylmorphine, and morphine in biological samples and validation of an LC-MS assay for delayed analyses of pharmacokinetic samples in rats. Journal of Pharmaceutical and Biomedical Analysis. 74: 291-7. PMID 23245263 DOI: 10.1016/J.Jpba.2012.10.033  0.333
2012 Teitelbaum AM, Gallardo JL, Bedi J, Giri R, Benoit AR, Olin MR, Morizio KM, Ohlfest JR, Remmel RP, Ferguson DM. 9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma. Cancer Chemotherapy and Pharmacology. 69: 1519-27. PMID 22402637 DOI: 10.1007/S00280-012-1855-5  0.717
2012 Conway JM, Birnbaum AK, Marino SE, Cloyd JC, Remmel RP. A sensitive capillary GC-MS method for analysis of topiramate from plasma obtained from single-dose studies. Biomedical Chromatography : Bmc. 26: 1071-6. PMID 22223467 DOI: 10.1002/Bmc.1749  0.324
2011 Zhou J, Argikar UA, Remmel RP. Functional analysis of UGT1A4(P24T) and UGT1A4(L48V) variant enzymes. Pharmacogenomics. 12: 1671-9. PMID 22047493 DOI: 10.2217/Pgs.11.105  0.604
2011 Aliwarga T, Cloyd JC, Goel V, Brundage RC, Marino SE, Leppik IE, Remmel RP. Excretion of the principal urinary metabolites of phenytoin and absolute oral bioavailability determined by use of a stable isotope in patients with epilepsy. Therapeutic Drug Monitoring. 33: 56-63. PMID 21233690 DOI: 10.1097/Ftd.0B013E3182081089  0.386
2011 Zhou J, Tracy TS, Remmel RP. Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 322-9. PMID 21030469 DOI: 10.1124/Dmd.110.035030  0.335
2011 Kumar A, Remmel RP, Mann HJ, Beilman GJ. Drug metabolism in hemorrhagic shock: pharmacokinetics of selective markers of cytochrome-P450 2C9, 2D6, and 3A4 enzyme activities in a porcine model. The Journal of Surgical Research. 167: e231-43. PMID 20850770 DOI: 10.1016/J.Jss.2010.06.040  0.353
2010 Vasan M, Neres J, Williams J, Wilson DJ, Teitelbaum AM, Remmel RP, Aldrich CC. Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening. Chemmedchem. 5: 2079-87. PMID 21053346 DOI: 10.1002/Cmdc.201000275  0.682
2010 Zhou J, Tracy TS, Remmel RP. Bilirubin glucuronidation revisited: proper assay conditions to estimate enzyme kinetics with recombinant UGT1A1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1907-11. PMID 20668247 DOI: 10.1124/Dmd.110.033829  0.35
2010 Chaudhry AS, Urban TJ, Lamba JK, Birnbaum AK, Remmel RP, Subramanian M, Strom S, You JH, Kasperaviciute D, Catarino CB, Radtke RA, Sisodiya SM, Goldstein DB, Schuetz EG. CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. The Journal of Pharmacology and Experimental Therapeutics. 332: 599-611. PMID 19855097 DOI: 10.1124/Jpet.109.161026  0.378
2010 Brophy CM, Luebke-Wheeler JL, Amiot BP, Remmel RP, Rinaldo P, Nyberg SL. Gene expression and functional analyses of primary rat hepatocytes on nanofiber matrices. Cells, Tissues, Organs. 191: 129-40. PMID 19494481 DOI: 10.1159/000223235  0.326
2009 Argikar UA, Senekeo-Effenberger K, Larson EE, Tukey RH, Remmel RP. Studies on induction of lamotrigine metabolism in transgenic UGT1 mice. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 39: 826-35. PMID 19845433 DOI: 10.3109/00498250903188985  0.657
2009 Argikar UA, Remmel RP. Variation in glucuronidation of lamotrigine in human liver microsomes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 39: 355-63. PMID 19387891 DOI: 10.1080/00498250902745082  0.68
2009 Brophy CM, Luebke-Wheeler JL, Amiot BP, Khan H, Remmel RP, Rinaldo P, Nyberg SL. Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function. Hepatology (Baltimore, Md.). 49: 578-86. PMID 19085959 DOI: 10.1002/Hep.22674  0.333
2009 Argikar UA, Remmel RP. Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 229-36. PMID 18838507 DOI: 10.1124/Dmd.108.022426  0.687
2008 Gupte A, Subramanian M, Remmel RP, Aldrich CC. Synthesis of deuterium-labelled 5'-O-[N-(Salicyl)sulfamoyl]adenosine (Sal-AMS-d(4)) as an internal standard for quantitation of Sal-AMS. Journal of Labelled Compounds & Radiopharmaceuticals. 51: 118-122. PMID 19050743 DOI: 10.1002/Jlcr.1490  0.343
2008 Johnson L, Orchard PJ, Baker KS, Brundage R, Cao Q, Wang X, Langer E, Farag-El Maasah S, Ross JA, Remmel R, Jacobson PA. Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation. Journal of Clinical Pharmacology. 48: 1052-62. PMID 18635758 DOI: 10.1177/0091270008321940  0.314
2008 Subramanian M, Birnbaum AK, Remmel RP. High-speed simultaneous determination of nine antiepileptic drugs using liquid chromatography-mass spectrometry. Therapeutic Drug Monitoring. 30: 347-56. PMID 18520607 DOI: 10.1097/Ftd.0B013E3181678Ecb  0.304
2007 Kumar A, Mann HJ, Remmel RP. Simultaneous analysis of cytochrome P450 probes-dextromethorphan, flurbiprofen and midazolam and their major metabolites by HPLC-mass-spectrometry/fluorescence after single-step extraction from plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 853: 287-93. PMID 17452028 DOI: 10.1016/J.Jchromb.2007.03.032  0.337
2007 Clemens PL, Cloyd JC, Kriel RL, Remmel RP. Relative bioavailability, metabolism and tolerability of rectally administered oxcarbazepine suspension. Clinical Drug Investigation. 27: 243-50. PMID 17358096 DOI: 10.2165/00044011-200727040-00003  0.367
2007 Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E, Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter JK, Barbier O, Tukey RH. Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 419-27. PMID 17151188 DOI: 10.1124/Dmd.106.013243  0.67
2006 Kumar A, Mann HJ, Remmel RP. Pharmacokinetics of tiletamine and zolazepam (Telazol) in anesthetized pigs. Journal of Veterinary Pharmacology and Therapeutics. 29: 587-9. PMID 17083465 DOI: 10.1111/J.1365-2885.2006.00798.X  0.317
2006 Argikar UA, Cloyd JC, Birnbaum AK, Leppik IE, Conway J, Kshirsagar S, Oetting WS, Klein EC, Remmel RP. Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients. Epilepsy Research. 71: 54-63. PMID 16815679 DOI: 10.1016/J.Eplepsyres.2006.05.015  0.641
2006 Kumar A, Mann HJ, Remmel RP. Determination of constituents of Telazol--tiletamine and zolazepam by a gas chromatography/mass spectrometry-based method. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 842: 131-5. PMID 16769259 DOI: 10.1016/J.Jchromb.2006.05.014  0.318
2006 Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ. In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG Proceedings of the National Academy of Sciences of the United States of America. 103: 6665-6669. PMID 16614064 DOI: 10.1073/Pnas.0602017103  0.324
2006 Kirstein MN, Hassan I, Guire DE, Weller DR, Dagit JW, Fisher JE, Remmel RP. High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 835: 136-42. PMID 16584929 DOI: 10.1016/J.Jchromb.2006.03.023  0.351
2006 Kirstein MN, Brundage RC, Elmquist WF, Remmel RP, Marker PH, Guire DE, Yee D. Characterization of an in vitro cell culture bioreactor system to evaluate anti-neoplastic drug regimens. Breast Cancer Research and Treatment. 96: 217-25. PMID 16502018 DOI: 10.1007/S10549-005-9004-Z  0.307
2005 Jacobson P, Rogosheske J, Barker JN, Green K, Ng J, Weisdorf D, Tan Y, Long J, Remmel R, Sawchuk R, McGlave P. Relationship of mycophenolic acid exposure to clinical outcome after hematopoietic cell transplantation. Clinical Pharmacology and Therapeutics. 78: 486-500. PMID 16321615 DOI: 10.1016/J.Clpt.2005.08.009  0.61
2005 Chen S, Beaton D, Nguyen N, Senekeo-Effenberger K, Brace-Sinnokrak E, Argikar U, Remmel RP, Trottier J, Barbier O, Ritter JK, Tukey RH. Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. The Journal of Biological Chemistry. 280: 37547-57. PMID 16155002 DOI: 10.1074/Jbc.M506683200  0.66
2005 Nyberg SL, Hardin J, Amiot B, Argikar UA, Remmel RP, Rinaldo P. Rapid, large-scale formation of porcine hepatocyte spheroids in a novel spheroid reservoir bioartificial liver. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 11: 901-10. PMID 16035089 DOI: 10.1002/Lt.20446  0.656
2004 Peng JZ, Remmel RP, Sawchuk RJ. Inhibition of murine cytochrome P4501A by tacrine: in vitro studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 805-12. PMID 15258105 DOI: 10.1124/Dmd.32.8.805  0.388
2004 Remmel RP, Crews BC, Kozak KR, Kalgutkar AS, Marnett LJ, Algutkar AS. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 113-22. PMID 14709628 DOI: 10.1124/Dmd.32.1.113  0.393
2004 Nagar S, Remmel RP, Hebbel RP, Zimmerman CL. Metabolism of opioids is altered in liver microsomes of sickle cell transgenic mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 98-104. PMID 14709626 DOI: 10.1124/Dmd.32.1.98  0.334
2004 Remmel RP, Crews BC, Kozak KR, Kalgutkar AS, Marnett LJ. Erratum: Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: Identification of active metabolites (Drug Metabolism and Disposition (2004) 32 (13-122)) Drug Metabolism and Disposition. 32. DOI: 10.1124/Dmd.32.3.366  0.403
2002 Tzanakakis ES, Waxman DJ, Hansen LK, Remmel RP, Hu WS. Long-term enhancement of cytochrome P450 2B1/2 expression in rat hepatocyte spheroids through adenovirus-mediated gene transfer. Cell Biology and Toxicology. 18: 13-27. PMID 11991083 DOI: 10.1023/A:1014415128392  0.33
2001 Tzanakakis ES, Hsiao CC, Matsushita T, Remmel RP, Hu WS. Probing enhanced cytochrome P450 2B1/2 activity in rat hepatocyte spheroids through confocal laser scanning microscopy. Cell Transplantation. 10: 329-42. PMID 11437078 DOI: 10.3727/000000001783986783  0.347
2001 Nelson MH, Birnbaum AK, Remmel RP. Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors Epilepsy Research. 44: 71-82. PMID 11255075 DOI: 10.1016/S0920-1211(00)00203-5  0.318
2001 Birnbaum AK, Kriel RL, Im Y, Remmel RP. Relative bioavailability of lamotrigine chewable dispersible tablets administered rectally Pharmacotherapy. 21: 158-162. PMID 11213851 DOI: 10.1592/Phco.21.2.158.34104  0.347
2000 Fletcher CV, Acosta EP, Cheng H, Haubrich R, Fischl M, Raasch R, Mills C, Hu XJ, Katzenstein D, Remmel RP, Gulick RM. Competing drug-drug interactions among multidrug antiretroviral regimens used in the treatment of HIV-infected subjects: ACTG 884 Aids. 14: 2495-2501. PMID 11101060 DOI: 10.1097/00002030-200011100-00011  0.319
2000 Cloyd JC, Remmel RP. Antiepileptic drug pharmacokinetics and interactions: Impact on treatment of epilepsy Pharmacotherapy. 20. PMID 10937813 DOI: 10.1592/Phco.20.12.139S.35255  0.317
2000 Hosagrahara VP, Hansen LK, Beilman GJ, Remmel RP. Evaluation of the effect of culture matrices on induction of CYP3A isoforms in cultured porcine hepatocytes Chemico-Biological Interactions. 127: 91-106. PMID 10903421 DOI: 10.1016/S0009-2797(00)00163-0  0.308
2000 Birnbaum AK, Kriel RL, Burkhardt RT, Remmel RP. Rectal absorption of lamotrigine compressed tablets Epilepsia. 41: 850-853. PMID 10897156 DOI: 10.1111/J.1528-1157.2000.Tb00252.X  0.34
2000 Remmel RP, Kawle SP, Weller D, Fletcher CV. Simultaneous HPLC assay for quantification of indinavir, nelfinavir, ritonavir, and saquinavir in human plasma Clinical Chemistry. 46: 73-81. PMID 10620574 DOI: 10.1093/Clinchem/46.1.73  0.321
1999 Friend JR, Wu FJ, Hansen LK, Remmel RP, Hu WS. Formation and characterization of hepatocyte spheroids. Methods in Molecular Medicine. 18: 245-52. PMID 21370181 DOI: 10.1385/0-89603-516-6:245  0.334
1999 Wu FJ, Friend JR, Remmel RP, Cerra FB, Hu WS. Enhanced cytochrome P450 IA1 activity of self-assembled rat hepatocyte spheroids. Cell Transplantation. 8: 233-46. PMID 10442736 DOI: 10.1177/096368979900800304  0.34
1999 Hsiao CC, Friend JR, Wu FJ, Ko WJ, Remmel RP, Hu WS. Receding cytochrome P450 activity in disassembling hepatocyte spheroids Tissue Engineering. 5: 207-221. PMID 10434069 DOI: 10.1089/Ten.1999.5.207  0.321
1998 Nelson MH, Birnbaum AK, Nyhus PJ, Remmel RP. A capillary GC-MS method for analysis of phenytoin and [13C3]-phenytoin from plasma obtained from pulse dose pharmacokinetic studies1 Journal of Pharmaceutical and Biomedical Analysis. 17: 1311-1323. PMID 9800650 DOI: 10.1016/S0731-7085(98)00018-1  0.331
1997 Hu WS, Friend JR, Wu FJ, Sielaff T, Peshwa MV, Lazar A, Nyberg SL, Remmel RP, Cerra FB. Development of a bioartificial liver employing xenogeneic hepatocytes. Cytotechnology. 23: 29-38. PMID 22358518 DOI: 10.1023/A:1007906512616  0.342
1996 Wu FJ, Friend JR, Lazar A, Mann HJ, Remmel RP, Cerra FB, Hu WS. Hollow fiber bioartificial liver utilizing collagen-entrapped porcine hepatocyte spheroids. Biotechnology and Bioengineering. 52: 34-44. PMID 18629850 DOI: 10.1002/(Sici)1097-0290(19961005)52:1<34::Aid-Bit4>3.0.Co;2-#  0.312
1995 Sielaff TD, Hu MY, Rao S, Groehler K, Olson D, Mann HJ, Remmel RP, Shatford RA, Amiot B, Hu WS. A technique for porcine hepatocyte harvest and description of differentiated metabolic functions in static culture. Transplantation. 59: 1459-63. PMID 7770934 DOI: 10.1097/00007890-199505270-00017  0.341
1995 Lazar A, Mann HJ, Remmel RP, Shatford RA, Cerra FB, Hu WS. Extended liver-specific functions of porcine hepatocyte spheroids entrapped in collagen gel. In Vitro Cellular & Developmental Biology. Animal. 31: 340-6. PMID 7633671 DOI: 10.1007/Bf02634282  0.366
1994 Lovdahl MJ, Reher KE, Mann HJ, Remmel RP. Determination of 4-methyl umbelliferone and metabolites in Williams E media and dog plasma by high performance liquid chromatography Journal of Liquid Chromatography. 17: 1795-1809. DOI: 10.1080/10826079408013459  0.309
1993 Wagner ML, Remmel RP, Graves NM, Leppik IE. Effect of felbamate on carbamazepine and its major metabolites. Clinical Pharmacology and Therapeutics. 53: 536-43. PMID 8491065 DOI: 10.1038/Clpt.1993.67  0.342
1993 Remmel RP, Burchell B. Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions Biochemical Pharmacology. 46: 559-566. PMID 8363629 DOI: 10.1016/0006-2952(93)90538-8  0.317
1993 Nyberg SL, Shirabe K, Peshwa MV, Sielaff TD, Crotty PL, Mann HJ, Remmel RP, Payne WD, Hu WS, Cerra FB. Extracorporeal application of a gel-entrapment, bioartificial liver: demonstration of drug metabolism and other biochemical functions. Cell Transplantation. 2: 441-52. PMID 8167929 DOI: 10.1177/096368979300200602  0.375
1993 Nyberg SL, Mann HJ, Remmel RP, Hu W, Cerra FB. Pharmacokinetic analysis verifies P450 function during in vitro and in vivo application of a bioartificial liver Asaio Journal. 39. DOI: 10.1097/00002480-199339030-00020  0.377
1991 Huang SH, Remmel RP, Zimmerman CL. The bioavailability and nonlinear clearance of (-)-carbovir in the rat. Pharmaceutical Research. 8: 739-43. PMID 2062804 DOI: 10.1023/A:1015850017201  0.36
1991 Sinz MW, Remmel RP. Analysis of lamotrigine and lamotrigine 2-N-glucuronide in guinea pig blood and urine by reserved-phase ion-pairing liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. 571: 217-230. PMID 1810949 DOI: 10.1016/0378-4347(91)80448-L  0.327
1990 Remmel RP, Sinz MW, Cloyd JC. Dose-Dependent Pharmacokinetics of Carbamazepine in Rats: Determination of the Formation Clearance of Carbamazepine-10,11-epoxide Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 7: 513-517. PMID 2367320 DOI: 10.1023/A:1015872901523  0.35
1990 Remmel RP, Miller SA, Graves NM. Simultaneous assay of felbamate plus carbamazepine, phenytoin, and their metabolites by liquid chromatography with mobile phase optimization Therapeutic Drug Monitoring. 12: 90-96. PMID 2305427 DOI: 10.1097/00007691-199001000-00017  0.334
1990 Straka RJ, Johnson KA, Marshall PS, Remmel RP. Analysis of metoprolol enantiomers in human serum by liquid chromatography on a cellulose-based chiral stationary phase Journal of Chromatography B: Biomedical Sciences and Applications. 530: 83-93. PMID 2277122 DOI: 10.1016/S0378-4347(00)82305-1  0.301
1990 Remmel RP, Huang SH, Hoff D, Zimmerman CL. Improved fluorometric high-performance liquid chromatographic assay for (-)-carbovir in rat blood and urine. Journal of Chromatography. 534: 109-18. PMID 2094697 DOI: 10.1016/S0378-4347(00)82153-2  0.339
1989 Remmel RP, Yeom YH, Hua M, Vince R, Zimmerman CL. Liquid chromatographic assay of carbovir, a carbocyclic nucleoside active against human immunodeficiency virus. Journal of Chromatography. 489: 323-31. PMID 2753956 DOI: 10.1016/S0378-4347(00)82910-2  0.327
1989 Yeom YH, Remmel RP, Huang SH, Hua M, Vince R, Zimmerman CL. Pharmacokinetics and bioavailability of carbovir, a carbocyclic nucleoside active against human immunodeficiency virus, in rats. Antimicrobial Agents and Chemotherapy. 33: 171-5. PMID 2719460 DOI: 10.1128/Aac.33.2.171  0.379
1989 Graves NM, Remmel RP, Rosenfeld WE, Carlson GH, Kriel RD, Holmes GB. Absorption of Valproic Acid Suppositories in Human Volunteers Archives of Neurology. 46: 906-909. PMID 2502974 DOI: 10.1001/Archneur.1989.00520440100026  0.317
1988 Fuerst RH, Graves NM, Leppik IE, Brundage RC, Holmes GB, Remmel RP. Felbamate increases phenytoin but decreases carbamazepine concentrations Epilepsia. 29: 488-491. PMID 3391153 DOI: 10.1111/J.1528-1157.1988.Tb03750.X  0.329
1984 Elmer GW, Remmel RP. Role of the intestinal microflora in clonazepam metabolism in the rat Xenobiotica. 14: 829-840. PMID 6506755 DOI: 10.3109/00498258409151481  0.681
1983 Remmel RP, Elmer GW. Separation of clonazepam and five metabolites by reverse phase HPLC and quantitation from rat liver microsomal incubations Journal of Liquid Chromatography. 6: 585-598. DOI: 10.1080/01483918308076070  0.65
1981 Remmel RP, Elmer GW. The effect of broad-spectrum antibiotics on warfarin excretion and metabolism in the rat Research Communications in Chemical Pathology and Pharmacology. 34: 503-514. PMID 7323446  0.653
1981 Remmel RP, Pohl LR, Elmer GW. Influence of the intestinal microflora on the elimination of warfarin in the rat Drug Metabolism and Disposition. 9: 410-414. PMID 6117438  0.63
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