Year |
Citation |
Score |
2019 |
Mohamed ME, Schladt DP, Guan W, Wu B, van Setten J, Keating B, Iklé D, Remmel RP, Dorr CR, Mannon RB, Matas AJ, Israni AK, Oetting WS, Jacobson PA. Tacrolimus Troughs and Genetic Determinants of Metabolism in Kidney Transplant Recipients: A comparison of four ancestry groups. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30953600 DOI: 10.1111/Ajt.15385 |
0.32 |
|
2018 |
Roslawski MJ, Remmel RP, Karanam A, Leppik IE, Marino SE, Birnbaum AK. Simultaneous quantification of thirteen cannabinoids and metabolites in human plasma by liquid chromatography tandem mass spectrometry in adult epilepsy patients. Therapeutic Drug Monitoring. PMID 30520828 DOI: 10.1097/Ftd.0000000000000583 |
0.327 |
|
2018 |
Dorr CR, Wu B, Remmel RP, Muthusamy A, Schladt DP, Abrahante JE, Guan W, Mannon RB, Matas AJ, Oetting WS, Jacobson PA, Israni AK. Identification of genetic variants associated with tacrolimus metabolism in kidney transplant recipients by extreme phenotype sampling and next generation sequencing. The Pharmacogenomics Journal. PMID 30442921 DOI: 10.1038/S41397-018-0063-Z |
0.308 |
|
2018 |
Scheibner A, Remmel R, Schladt D, Oetting W, Guan W, Wu B, Dorr C, Israni A, Jacobson PA. Tacrolimus Elimination in Four Patients with a CYP3A5*3/*3 CYP3A4*22/*22 Genotype. Pharmacotherapy. PMID 29804290 DOI: 10.1002/Phar.2131 |
0.357 |
|
2017 |
Oetting WS, Wu B, Schladt DP, Guan W, Remmel RP, Mannon RB, Matas AJ, Israni AK, Jacobson PA. Genome-wide association study identifies the common variants in CYP3A4 and CYP3A5 responsible for variation in tacrolimus trough concentration in Caucasian kidney transplant recipients. The Pharmacogenomics Journal. PMID 29160300 DOI: 10.1038/Tpj.2017.49 |
0.32 |
|
2017 |
Dorr CR, Remmel RP, Muthusamy A, Fisher J, Moriarity B, Yasuda K, Wu B, Guan W, Schuetz EG, Oetting WS, Jacobson PA, Israni AK. CRISPR/Cas9 genetic modification of CYP3A5 *3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28533324 DOI: 10.1124/Dmd.117.076307 |
0.321 |
|
2016 |
Dawadi S, Kawamura S, Rubenstein A, Remmel R, Aldrich CC. Synthesis and pharmacological evaluation of nucleoside prodrugs designed to target siderophore biosynthesis in Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry. PMID 26875934 DOI: 10.1016/J.Bmc.2016.02.002 |
0.351 |
|
2015 |
Sanghavi K, Brundage RC, Miller MB, Schladt DP, Israni AK, Guan W, Oetting WS, Mannon RB, Remmel RP, Matas AJ, Jacobson PA. Genotype-guided tacrolimus dosing in African-American kidney transplant recipients. The Pharmacogenomics Journal. PMID 26667830 DOI: 10.1038/Tpj.2015.87 |
0.358 |
|
2015 |
Oetting WS, Schladt DP, Guan W, Miller MB, Remmel RP, Dorr C, Sanghavi K, Mannon RB, Herrera B, Matas AJ, Salomon DR, Kwok PY, Keating BJ, Israni AK, Jacobson PA, et al. Genomewide Association Study of Tacrolimus Concentrations in African American Kidney Transplant Recipients Identifies Multiple CYP3A5 Alleles. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26485092 DOI: 10.1111/Ajt.13495 |
0.305 |
|
2015 |
Polepally AR, Remmel RP, Brundage RC, Leppik IE, Rarick JO, Ramsay RE, Birnbaum AK. Steady-state pharmacokinetics and bioavailability of immediate-release and extended-release formulations of lamotrigine in elderly epilepsy patients: Use of stable isotope methodology. Journal of Clinical Pharmacology. 55: 1101-8. PMID 25903807 DOI: 10.1002/Jcph.522 |
0.305 |
|
2014 |
Conway JM, Birnbaum AK, Leppik IE, Pennell PB, White JR, Rarick JO, Remmel RP. Safety of an intravenous formulation of lamotrigine. Seizure. 23: 390-2. PMID 24560492 DOI: 10.1016/J.Seizure.2014.01.019 |
0.301 |
|
2014 |
Kumar A, Mann HJ, Remmel RP, Beilman GJ, Kaila N. Pharmacokinetic study in pigs and in vitro metabolic characterization in pig- and human-liver microsomes reveal marked differences in disposition and metabolism of tiletamine and zolazepam (Telazol). Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 44: 379-90. PMID 24020890 DOI: 10.3109/00498254.2013.833362 |
0.423 |
|
2013 |
Teitelbaum AM, Meissner A, Harding RA, Wong CA, Aldrich CC, Remmel RP. Synthesis, pH-dependent, and plasma stability of meropenem prodrugs for potential use against drug-resistant tuberculosis. Bioorganic & Medicinal Chemistry. 21: 5605-17. PMID 23845282 DOI: 10.1016/J.Bmc.2013.05.024 |
0.706 |
|
2013 |
Jones JM, Raleigh MD, Pentel PR, Harmon TM, Keyler DE, Remmel RP, Birnbaum AK. Stability of heroin, 6-monoacetylmorphine, and morphine in biological samples and validation of an LC-MS assay for delayed analyses of pharmacokinetic samples in rats. Journal of Pharmaceutical and Biomedical Analysis. 74: 291-7. PMID 23245263 DOI: 10.1016/J.Jpba.2012.10.033 |
0.333 |
|
2012 |
Teitelbaum AM, Gallardo JL, Bedi J, Giri R, Benoit AR, Olin MR, Morizio KM, Ohlfest JR, Remmel RP, Ferguson DM. 9-Amino acridine pharmacokinetics, brain distribution, and in vitro/in vivo efficacy against malignant glioma. Cancer Chemotherapy and Pharmacology. 69: 1519-27. PMID 22402637 DOI: 10.1007/S00280-012-1855-5 |
0.717 |
|
2012 |
Conway JM, Birnbaum AK, Marino SE, Cloyd JC, Remmel RP. A sensitive capillary GC-MS method for analysis of topiramate from plasma obtained from single-dose studies. Biomedical Chromatography : Bmc. 26: 1071-6. PMID 22223467 DOI: 10.1002/Bmc.1749 |
0.324 |
|
2011 |
Zhou J, Argikar UA, Remmel RP. Functional analysis of UGT1A4(P24T) and UGT1A4(L48V) variant enzymes. Pharmacogenomics. 12: 1671-9. PMID 22047493 DOI: 10.2217/Pgs.11.105 |
0.604 |
|
2011 |
Aliwarga T, Cloyd JC, Goel V, Brundage RC, Marino SE, Leppik IE, Remmel RP. Excretion of the principal urinary metabolites of phenytoin and absolute oral bioavailability determined by use of a stable isotope in patients with epilepsy. Therapeutic Drug Monitoring. 33: 56-63. PMID 21233690 DOI: 10.1097/Ftd.0B013E3182081089 |
0.386 |
|
2011 |
Zhou J, Tracy TS, Remmel RP. Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 322-9. PMID 21030469 DOI: 10.1124/Dmd.110.035030 |
0.335 |
|
2011 |
Kumar A, Remmel RP, Mann HJ, Beilman GJ. Drug metabolism in hemorrhagic shock: pharmacokinetics of selective markers of cytochrome-P450 2C9, 2D6, and 3A4 enzyme activities in a porcine model. The Journal of Surgical Research. 167: e231-43. PMID 20850770 DOI: 10.1016/J.Jss.2010.06.040 |
0.353 |
|
2010 |
Vasan M, Neres J, Williams J, Wilson DJ, Teitelbaum AM, Remmel RP, Aldrich CC. Inhibitors of the salicylate synthase (MbtI) from Mycobacterium tuberculosis discovered by high-throughput screening. Chemmedchem. 5: 2079-87. PMID 21053346 DOI: 10.1002/Cmdc.201000275 |
0.682 |
|
2010 |
Zhou J, Tracy TS, Remmel RP. Bilirubin glucuronidation revisited: proper assay conditions to estimate enzyme kinetics with recombinant UGT1A1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 38: 1907-11. PMID 20668247 DOI: 10.1124/Dmd.110.033829 |
0.35 |
|
2010 |
Chaudhry AS, Urban TJ, Lamba JK, Birnbaum AK, Remmel RP, Subramanian M, Strom S, You JH, Kasperaviciute D, Catarino CB, Radtke RA, Sisodiya SM, Goldstein DB, Schuetz EG. CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin autoinduction of clearance and maintenance dose. The Journal of Pharmacology and Experimental Therapeutics. 332: 599-611. PMID 19855097 DOI: 10.1124/Jpet.109.161026 |
0.378 |
|
2010 |
Brophy CM, Luebke-Wheeler JL, Amiot BP, Remmel RP, Rinaldo P, Nyberg SL. Gene expression and functional analyses of primary rat hepatocytes on nanofiber matrices. Cells, Tissues, Organs. 191: 129-40. PMID 19494481 DOI: 10.1159/000223235 |
0.326 |
|
2009 |
Argikar UA, Senekeo-Effenberger K, Larson EE, Tukey RH, Remmel RP. Studies on induction of lamotrigine metabolism in transgenic UGT1 mice. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 39: 826-35. PMID 19845433 DOI: 10.3109/00498250903188985 |
0.657 |
|
2009 |
Argikar UA, Remmel RP. Variation in glucuronidation of lamotrigine in human liver microsomes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 39: 355-63. PMID 19387891 DOI: 10.1080/00498250902745082 |
0.68 |
|
2009 |
Brophy CM, Luebke-Wheeler JL, Amiot BP, Khan H, Remmel RP, Rinaldo P, Nyberg SL. Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function. Hepatology (Baltimore, Md.). 49: 578-86. PMID 19085959 DOI: 10.1002/Hep.22674 |
0.333 |
|
2009 |
Argikar UA, Remmel RP. Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 229-36. PMID 18838507 DOI: 10.1124/Dmd.108.022426 |
0.687 |
|
2008 |
Gupte A, Subramanian M, Remmel RP, Aldrich CC. Synthesis of deuterium-labelled 5'-O-[N-(Salicyl)sulfamoyl]adenosine (Sal-AMS-d(4)) as an internal standard for quantitation of Sal-AMS. Journal of Labelled Compounds & Radiopharmaceuticals. 51: 118-122. PMID 19050743 DOI: 10.1002/Jlcr.1490 |
0.343 |
|
2008 |
Johnson L, Orchard PJ, Baker KS, Brundage R, Cao Q, Wang X, Langer E, Farag-El Maasah S, Ross JA, Remmel R, Jacobson PA. Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation. Journal of Clinical Pharmacology. 48: 1052-62. PMID 18635758 DOI: 10.1177/0091270008321940 |
0.314 |
|
2008 |
Subramanian M, Birnbaum AK, Remmel RP. High-speed simultaneous determination of nine antiepileptic drugs using liquid chromatography-mass spectrometry. Therapeutic Drug Monitoring. 30: 347-56. PMID 18520607 DOI: 10.1097/Ftd.0B013E3181678Ecb |
0.304 |
|
2007 |
Kumar A, Mann HJ, Remmel RP. Simultaneous analysis of cytochrome P450 probes-dextromethorphan, flurbiprofen and midazolam and their major metabolites by HPLC-mass-spectrometry/fluorescence after single-step extraction from plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 853: 287-93. PMID 17452028 DOI: 10.1016/J.Jchromb.2007.03.032 |
0.337 |
|
2007 |
Clemens PL, Cloyd JC, Kriel RL, Remmel RP. Relative bioavailability, metabolism and tolerability of rectally administered oxcarbazepine suspension. Clinical Drug Investigation. 27: 243-50. PMID 17358096 DOI: 10.2165/00044011-200727040-00003 |
0.367 |
|
2007 |
Senekeo-Effenberger K, Chen S, Brace-Sinnokrak E, Bonzo JA, Yueh MF, Argikar U, Kaeding J, Trottier J, Remmel RP, Ritter JK, Barbier O, Tukey RH. Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 419-27. PMID 17151188 DOI: 10.1124/Dmd.106.013243 |
0.67 |
|
2006 |
Kumar A, Mann HJ, Remmel RP. Pharmacokinetics of tiletamine and zolazepam (Telazol) in anesthetized pigs. Journal of Veterinary Pharmacology and Therapeutics. 29: 587-9. PMID 17083465 DOI: 10.1111/J.1365-2885.2006.00798.X |
0.317 |
|
2006 |
Argikar UA, Cloyd JC, Birnbaum AK, Leppik IE, Conway J, Kshirsagar S, Oetting WS, Klein EC, Remmel RP. Paradoxical urinary phenytoin metabolite (S)/(R) ratios in CYP2C19*1/*2 patients. Epilepsy Research. 71: 54-63. PMID 16815679 DOI: 10.1016/J.Eplepsyres.2006.05.015 |
0.641 |
|
2006 |
Kumar A, Mann HJ, Remmel RP. Determination of constituents of Telazol--tiletamine and zolazepam by a gas chromatography/mass spectrometry-based method. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 842: 131-5. PMID 16769259 DOI: 10.1016/J.Jchromb.2006.05.014 |
0.318 |
|
2006 |
Otteneder MB, Knutson CG, Daniels JS, Hashim M, Crews BC, Remmel RP, Wang H, Rizzo C, Marnett LJ. In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M1dG Proceedings of the National Academy of Sciences of the United States of America. 103: 6665-6669. PMID 16614064 DOI: 10.1073/Pnas.0602017103 |
0.324 |
|
2006 |
Kirstein MN, Hassan I, Guire DE, Weller DR, Dagit JW, Fisher JE, Remmel RP. High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 835: 136-42. PMID 16584929 DOI: 10.1016/J.Jchromb.2006.03.023 |
0.351 |
|
2006 |
Kirstein MN, Brundage RC, Elmquist WF, Remmel RP, Marker PH, Guire DE, Yee D. Characterization of an in vitro cell culture bioreactor system to evaluate anti-neoplastic drug regimens. Breast Cancer Research and Treatment. 96: 217-25. PMID 16502018 DOI: 10.1007/S10549-005-9004-Z |
0.307 |
|
2005 |
Jacobson P, Rogosheske J, Barker JN, Green K, Ng J, Weisdorf D, Tan Y, Long J, Remmel R, Sawchuk R, McGlave P. Relationship of mycophenolic acid exposure to clinical outcome after hematopoietic cell transplantation. Clinical Pharmacology and Therapeutics. 78: 486-500. PMID 16321615 DOI: 10.1016/J.Clpt.2005.08.009 |
0.61 |
|
2005 |
Chen S, Beaton D, Nguyen N, Senekeo-Effenberger K, Brace-Sinnokrak E, Argikar U, Remmel RP, Trottier J, Barbier O, Ritter JK, Tukey RH. Tissue-specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus. The Journal of Biological Chemistry. 280: 37547-57. PMID 16155002 DOI: 10.1074/Jbc.M506683200 |
0.66 |
|
2005 |
Nyberg SL, Hardin J, Amiot B, Argikar UA, Remmel RP, Rinaldo P. Rapid, large-scale formation of porcine hepatocyte spheroids in a novel spheroid reservoir bioartificial liver. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 11: 901-10. PMID 16035089 DOI: 10.1002/Lt.20446 |
0.656 |
|
2004 |
Peng JZ, Remmel RP, Sawchuk RJ. Inhibition of murine cytochrome P4501A by tacrine: in vitro studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 805-12. PMID 15258105 DOI: 10.1124/Dmd.32.8.805 |
0.388 |
|
2004 |
Remmel RP, Crews BC, Kozak KR, Kalgutkar AS, Marnett LJ, Algutkar AS. Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: identification of active metabolites. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 113-22. PMID 14709628 DOI: 10.1124/Dmd.32.1.113 |
0.393 |
|
2004 |
Nagar S, Remmel RP, Hebbel RP, Zimmerman CL. Metabolism of opioids is altered in liver microsomes of sickle cell transgenic mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 32: 98-104. PMID 14709626 DOI: 10.1124/Dmd.32.1.98 |
0.334 |
|
2004 |
Remmel RP, Crews BC, Kozak KR, Kalgutkar AS, Marnett LJ. Erratum: Studies on the metabolism of the novel, selective cyclooxygenase-2 inhibitor indomethacin phenethylamide in rat, mouse, and human liver microsomes: Identification of active metabolites (Drug Metabolism and Disposition (2004) 32 (13-122)) Drug Metabolism and Disposition. 32. DOI: 10.1124/Dmd.32.3.366 |
0.403 |
|
2002 |
Tzanakakis ES, Waxman DJ, Hansen LK, Remmel RP, Hu WS. Long-term enhancement of cytochrome P450 2B1/2 expression in rat hepatocyte spheroids through adenovirus-mediated gene transfer. Cell Biology and Toxicology. 18: 13-27. PMID 11991083 DOI: 10.1023/A:1014415128392 |
0.33 |
|
2001 |
Tzanakakis ES, Hsiao CC, Matsushita T, Remmel RP, Hu WS. Probing enhanced cytochrome P450 2B1/2 activity in rat hepatocyte spheroids through confocal laser scanning microscopy. Cell Transplantation. 10: 329-42. PMID 11437078 DOI: 10.3727/000000001783986783 |
0.347 |
|
2001 |
Nelson MH, Birnbaum AK, Remmel RP. Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors Epilepsy Research. 44: 71-82. PMID 11255075 DOI: 10.1016/S0920-1211(00)00203-5 |
0.318 |
|
2001 |
Birnbaum AK, Kriel RL, Im Y, Remmel RP. Relative bioavailability of lamotrigine chewable dispersible tablets administered rectally Pharmacotherapy. 21: 158-162. PMID 11213851 DOI: 10.1592/Phco.21.2.158.34104 |
0.347 |
|
2000 |
Fletcher CV, Acosta EP, Cheng H, Haubrich R, Fischl M, Raasch R, Mills C, Hu XJ, Katzenstein D, Remmel RP, Gulick RM. Competing drug-drug interactions among multidrug antiretroviral regimens used in the treatment of HIV-infected subjects: ACTG 884 Aids. 14: 2495-2501. PMID 11101060 DOI: 10.1097/00002030-200011100-00011 |
0.319 |
|
2000 |
Cloyd JC, Remmel RP. Antiepileptic drug pharmacokinetics and interactions: Impact on treatment of epilepsy Pharmacotherapy. 20. PMID 10937813 DOI: 10.1592/Phco.20.12.139S.35255 |
0.317 |
|
2000 |
Hosagrahara VP, Hansen LK, Beilman GJ, Remmel RP. Evaluation of the effect of culture matrices on induction of CYP3A isoforms in cultured porcine hepatocytes Chemico-Biological Interactions. 127: 91-106. PMID 10903421 DOI: 10.1016/S0009-2797(00)00163-0 |
0.308 |
|
2000 |
Birnbaum AK, Kriel RL, Burkhardt RT, Remmel RP. Rectal absorption of lamotrigine compressed tablets Epilepsia. 41: 850-853. PMID 10897156 DOI: 10.1111/J.1528-1157.2000.Tb00252.X |
0.34 |
|
2000 |
Remmel RP, Kawle SP, Weller D, Fletcher CV. Simultaneous HPLC assay for quantification of indinavir, nelfinavir, ritonavir, and saquinavir in human plasma Clinical Chemistry. 46: 73-81. PMID 10620574 DOI: 10.1093/Clinchem/46.1.73 |
0.321 |
|
1999 |
Friend JR, Wu FJ, Hansen LK, Remmel RP, Hu WS. Formation and characterization of hepatocyte spheroids. Methods in Molecular Medicine. 18: 245-52. PMID 21370181 DOI: 10.1385/0-89603-516-6:245 |
0.334 |
|
1999 |
Wu FJ, Friend JR, Remmel RP, Cerra FB, Hu WS. Enhanced cytochrome P450 IA1 activity of self-assembled rat hepatocyte spheroids. Cell Transplantation. 8: 233-46. PMID 10442736 DOI: 10.1177/096368979900800304 |
0.34 |
|
1999 |
Hsiao CC, Friend JR, Wu FJ, Ko WJ, Remmel RP, Hu WS. Receding cytochrome P450 activity in disassembling hepatocyte spheroids Tissue Engineering. 5: 207-221. PMID 10434069 DOI: 10.1089/Ten.1999.5.207 |
0.321 |
|
1998 |
Nelson MH, Birnbaum AK, Nyhus PJ, Remmel RP. A capillary GC-MS method for analysis of phenytoin and [13C3]-phenytoin from plasma obtained from pulse dose pharmacokinetic studies1 Journal of Pharmaceutical and Biomedical Analysis. 17: 1311-1323. PMID 9800650 DOI: 10.1016/S0731-7085(98)00018-1 |
0.331 |
|
1997 |
Hu WS, Friend JR, Wu FJ, Sielaff T, Peshwa MV, Lazar A, Nyberg SL, Remmel RP, Cerra FB. Development of a bioartificial liver employing xenogeneic hepatocytes. Cytotechnology. 23: 29-38. PMID 22358518 DOI: 10.1023/A:1007906512616 |
0.342 |
|
1996 |
Wu FJ, Friend JR, Lazar A, Mann HJ, Remmel RP, Cerra FB, Hu WS. Hollow fiber bioartificial liver utilizing collagen-entrapped porcine hepatocyte spheroids. Biotechnology and Bioengineering. 52: 34-44. PMID 18629850 DOI: 10.1002/(Sici)1097-0290(19961005)52:1<34::Aid-Bit4>3.0.Co;2-# |
0.312 |
|
1995 |
Sielaff TD, Hu MY, Rao S, Groehler K, Olson D, Mann HJ, Remmel RP, Shatford RA, Amiot B, Hu WS. A technique for porcine hepatocyte harvest and description of differentiated metabolic functions in static culture. Transplantation. 59: 1459-63. PMID 7770934 DOI: 10.1097/00007890-199505270-00017 |
0.341 |
|
1995 |
Lazar A, Mann HJ, Remmel RP, Shatford RA, Cerra FB, Hu WS. Extended liver-specific functions of porcine hepatocyte spheroids entrapped in collagen gel. In Vitro Cellular & Developmental Biology. Animal. 31: 340-6. PMID 7633671 DOI: 10.1007/Bf02634282 |
0.366 |
|
1994 |
Lovdahl MJ, Reher KE, Mann HJ, Remmel RP. Determination of 4-methyl umbelliferone and metabolites in Williams E media and dog plasma by high performance liquid chromatography Journal of Liquid Chromatography. 17: 1795-1809. DOI: 10.1080/10826079408013459 |
0.309 |
|
1993 |
Wagner ML, Remmel RP, Graves NM, Leppik IE. Effect of felbamate on carbamazepine and its major metabolites. Clinical Pharmacology and Therapeutics. 53: 536-43. PMID 8491065 DOI: 10.1038/Clpt.1993.67 |
0.342 |
|
1993 |
Remmel RP, Burchell B. Validation and use of cloned, expressed human drug-metabolizing enzymes in heterologous cells for analysis of drug metabolism and drug-drug interactions Biochemical Pharmacology. 46: 559-566. PMID 8363629 DOI: 10.1016/0006-2952(93)90538-8 |
0.317 |
|
1993 |
Nyberg SL, Shirabe K, Peshwa MV, Sielaff TD, Crotty PL, Mann HJ, Remmel RP, Payne WD, Hu WS, Cerra FB. Extracorporeal application of a gel-entrapment, bioartificial liver: demonstration of drug metabolism and other biochemical functions. Cell Transplantation. 2: 441-52. PMID 8167929 DOI: 10.1177/096368979300200602 |
0.375 |
|
1993 |
Nyberg SL, Mann HJ, Remmel RP, Hu W, Cerra FB. Pharmacokinetic analysis verifies P450 function during in vitro and in vivo application of a bioartificial liver Asaio Journal. 39. DOI: 10.1097/00002480-199339030-00020 |
0.377 |
|
1991 |
Huang SH, Remmel RP, Zimmerman CL. The bioavailability and nonlinear clearance of (-)-carbovir in the rat. Pharmaceutical Research. 8: 739-43. PMID 2062804 DOI: 10.1023/A:1015850017201 |
0.36 |
|
1991 |
Sinz MW, Remmel RP. Analysis of lamotrigine and lamotrigine 2-N-glucuronide in guinea pig blood and urine by reserved-phase ion-pairing liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. 571: 217-230. PMID 1810949 DOI: 10.1016/0378-4347(91)80448-L |
0.327 |
|
1990 |
Remmel RP, Sinz MW, Cloyd JC. Dose-Dependent Pharmacokinetics of Carbamazepine in Rats: Determination of the Formation Clearance of Carbamazepine-10,11-epoxide Pharmaceutical Research: An Official Journal of the American Association of Pharmaceutical Scientists. 7: 513-517. PMID 2367320 DOI: 10.1023/A:1015872901523 |
0.35 |
|
1990 |
Remmel RP, Miller SA, Graves NM. Simultaneous assay of felbamate plus carbamazepine, phenytoin, and their metabolites by liquid chromatography with mobile phase optimization Therapeutic Drug Monitoring. 12: 90-96. PMID 2305427 DOI: 10.1097/00007691-199001000-00017 |
0.334 |
|
1990 |
Straka RJ, Johnson KA, Marshall PS, Remmel RP. Analysis of metoprolol enantiomers in human serum by liquid chromatography on a cellulose-based chiral stationary phase Journal of Chromatography B: Biomedical Sciences and Applications. 530: 83-93. PMID 2277122 DOI: 10.1016/S0378-4347(00)82305-1 |
0.301 |
|
1990 |
Remmel RP, Huang SH, Hoff D, Zimmerman CL. Improved fluorometric high-performance liquid chromatographic assay for (-)-carbovir in rat blood and urine. Journal of Chromatography. 534: 109-18. PMID 2094697 DOI: 10.1016/S0378-4347(00)82153-2 |
0.339 |
|
1989 |
Remmel RP, Yeom YH, Hua M, Vince R, Zimmerman CL. Liquid chromatographic assay of carbovir, a carbocyclic nucleoside active against human immunodeficiency virus. Journal of Chromatography. 489: 323-31. PMID 2753956 DOI: 10.1016/S0378-4347(00)82910-2 |
0.327 |
|
1989 |
Yeom YH, Remmel RP, Huang SH, Hua M, Vince R, Zimmerman CL. Pharmacokinetics and bioavailability of carbovir, a carbocyclic nucleoside active against human immunodeficiency virus, in rats. Antimicrobial Agents and Chemotherapy. 33: 171-5. PMID 2719460 DOI: 10.1128/Aac.33.2.171 |
0.379 |
|
1989 |
Graves NM, Remmel RP, Rosenfeld WE, Carlson GH, Kriel RD, Holmes GB. Absorption of Valproic Acid Suppositories in Human Volunteers Archives of Neurology. 46: 906-909. PMID 2502974 DOI: 10.1001/Archneur.1989.00520440100026 |
0.317 |
|
1988 |
Fuerst RH, Graves NM, Leppik IE, Brundage RC, Holmes GB, Remmel RP. Felbamate increases phenytoin but decreases carbamazepine concentrations Epilepsia. 29: 488-491. PMID 3391153 DOI: 10.1111/J.1528-1157.1988.Tb03750.X |
0.329 |
|
1984 |
Elmer GW, Remmel RP. Role of the intestinal microflora in clonazepam metabolism in the rat Xenobiotica. 14: 829-840. PMID 6506755 DOI: 10.3109/00498258409151481 |
0.681 |
|
1983 |
Remmel RP, Elmer GW. Separation of clonazepam and five metabolites by reverse phase HPLC and quantitation from rat liver microsomal incubations Journal of Liquid Chromatography. 6: 585-598. DOI: 10.1080/01483918308076070 |
0.65 |
|
1981 |
Remmel RP, Elmer GW. The effect of broad-spectrum antibiotics on warfarin excretion and metabolism in the rat Research Communications in Chemical Pathology and Pharmacology. 34: 503-514. PMID 7323446 |
0.653 |
|
1981 |
Remmel RP, Pohl LR, Elmer GW. Influence of the intestinal microflora on the elimination of warfarin in the rat Drug Metabolism and Disposition. 9: 410-414. PMID 6117438 |
0.63 |
|
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