Nancie M. Archin, Ph.D. - Publications

Affiliations: 
2002 The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Microbiology Biology, Immunology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Joseph SB, Abrahams MR, Moeser M, Tyers L, Archin NM, Council OD, Sondgeroth A, Spielvogel E, Emery A, Zhou S, Doolabh D, Ismail SD, Karim SA, Margolis DM, Pond SK, et al. The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus. Plos Pathogens. 20: e1011974. PMID 38422171 DOI: 10.1371/journal.ppat.1011974  0.461
2024 Fenton AD, Archin N, Turner A-M, Joseph S, Moeser M, Margolis DM, Browne EP. A novel high-throughput microwell outgrowth assay for HIV-infected cells. Journal of Virology. e0179823. PMID 38376258 DOI: 10.1128/jvi.01798-23  0.357
2024 Gay CL, Hanley PJ, Falcinelli SD, Kuruc JD, Pedersen SM, Kirchherr J, Raines SLM, Motta CM, Lazarski C, Chansky P, Tanna J, Shibli A, Datar A, McCann CD, Sili U, ... ... Archin N, et al. The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy. The Journal of Infectious Diseases. PMID 38349333 DOI: 10.1093/infdis/jiad423  0.358
2023 Ling L, De C, Spagnuolo RA, Begum N, Falcinelli SD, Archin NM, Kovarova M, Silvestri G, Wahl A, Margolis DM, Garcia JV. Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice. Plos Pathogens. 19: e1011824. PMID 38055722 DOI: 10.1371/journal.ppat.1011824  0.337
2023 Van Gulck E, Pardons M, Nijs E, Verheyen N, Dockx K, Van Den Eynde C, Battivelli E, Vega J, Florence E, Autran B, Archin NM, Margolis DM, Katlama C, Hamimi C, Van Den Wyngaert I, et al. A truncated HIV Tat demonstrates potent and specific latency reversal activity. Antimicrobial Agents and Chemotherapy. e0041723. PMID 37874295 DOI: 10.1128/aac.00417-23  0.38
2023 Dashti A, Sukkestad S, Horner AM, Neja M, Siddiqi Z, Waller C, Goldy J, Monroe D, Lin A, Schoof N, Singh V, Mavigner M, Lifson JD, Deleage C, Tuyishime M, ... ... Archin NM, et al. AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques. Nature Medicine. 29: 2535-2546. PMID 37783968 DOI: 10.1038/s41591-023-02570-7  0.355
2023 Tang Y, Chaillon A, Gianella S, Wong LM, Li D, Simermeyer TL, Porrachia M, Ignacio C, Woodworth B, Zhong D, Du J, de la Parra Polina E, Kirchherr J, Allard B, Clohosey ML, ... ... Archin NM, et al. Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. The Journal of Clinical Investigation. 133. PMID 37317962 DOI: 10.1172/JCI167417  0.378
2022 Xu Y, Weideman AM, Abad-Fernandez M, Mollan KR, Kallon S, Samir S, Warren JA, Clutton G, Roan N, Adimora AA, Archin N, Kuruc J, Gay C, Hudgens MG, Goonetilleke N. CD8 T Cell Virus Inhibition Assay Protocol. Bio-Protocol. 12: e4354. PMID 35434196 DOI: 10.21769/BioProtoc.4354  0.304
2021 Deeks SG, Archin N, Cannon P, Collins S, Jones RB, de Jong MAWP, Lambotte O, Lamplough R, Ndung'u T, Sugarman J, Tiemessen CT, Vandekerckhove L, Lewin SR. Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021. Nature Medicine. PMID 34848888 DOI: 10.1038/s41591-021-01590-5  0.347
2021 Xu Y, Weideman AM, Abad-Fernandez M, Mollan KR, Kallon S, Samir S, Warren JA, Clutton G, Roan N, Adimora AA, Archin N, Kuruc J, Gay C, Hudgens MG, Goonetilleke N. Reliable Estimation of CD8 T Cell Inhibition of HIV-1 Replication. Frontiers in Immunology. 12: 666991. PMID 34276657 DOI: 10.3389/fimmu.2021.666991  0.308
2020 Warren JA, Zhou S, Xu Y, Moeser MJ, MacMillan DR, Council O, Kirchherr J, Sung JM, Roan N, Adimora AA, Joseph S, Kuruc JD, Gay CL, Margolis DM, Archin N, et al. The HIV-1 latent reservoir is largely sensitive to circulating T cells. Elife. 9. PMID 33021198 DOI: 10.7554/eLife.57246  0.357
2020 Neidleman J, Luo X, Frouard J, Xie G, Hsiao F, Ma T, Morcilla V, Lee A, Telwatte S, Thomas R, Tamaki W, Wheeler B, Hoh R, Somsouk M, Vohra P, ... ... Archin NM, et al. Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir. Elife. 9. PMID 32990219 DOI: 10.7554/eLife.60933  0.372
2020 Stuelke EL, James KS, Kirchherr JL, Allard B, Baker C, Kuruc JD, Gay CL, Margolis DM, Archin NM. Measuring the Inducible, Replication-Competent HIV Reservoir Using an Ultra-Sensitive p24 Readout, the Digital ELISA Viral Outgrowth Assay. Frontiers in Immunology. 11: 1971. PMID 32849659 DOI: 10.3389/fimmu.2020.01971  0.306
2020 Falcinelli SD, Shook-Sa BE, Dewey MG, Sridhar S, Read J, Kirchherr J, James KS, Allard B, Ghofrani S, Stuelke E, Baker C, Roan NR, Eron JJ, Kuruc JD, Ramirez C, ... ... Archin NM, et al. Impact of biological sex on immune activation and frequency of the latent HIV reservoir during suppressive antiretroviral therapy. The Journal of Infectious Diseases. PMID 32496542 DOI: 10.1093/Infdis/Jiaa298  0.316
2020 Turner AM, Dronamraju R, Potjewyd FM, Sholtis K, Winecoff D, Kirchherr J, Archin N, Browne E, Strahl BD, Margolis D, James LI. Evaluation of EED Inhibitors as a Class of PRC2-Targeted Small Molecules for HIV Latency Reversal. Acs Infectious Diseases. PMID 32347704 DOI: 10.1021/Acsinfecdis.9B00514  0.319
2020 Margolis DM, Archin NM, Cohen MS, Eron JJ, Ferrari G, Garcia JV, Gay CL, Goonetilleke N, Joseph SB, Swanstrom R, Turner AW, Wahl A. Curing HIV: Seeking to Target and Clear Persistent Infection. Cell. PMID 32220311 DOI: 10.1016/J.Cell.2020.03.005  0.323
2020 Nixon CC, Mavigner M, Sampey GC, Brooks AD, Spagnuolo RA, Irlbeck DM, Mattingly C, Ho PT, Schoof N, Cammon CG, Tharp GK, Kanke M, Wang Z, Cleary RA, Upadhyay AA, ... ... Archin NM, et al. Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo. Nature. PMID 31969707 DOI: 10.1038/S41586-020-1951-3  0.319
2019 James KS, Trumble I, Clohosey ML, Moeser M, Roan NR, Adimora AA, Joseph SB, Archin NM, Hudgens M, Soriano-Sarabia N. Measuring the contribution of γδ T cells to the persistent HIV reservoir. Aids (London, England). PMID 31764074 DOI: 10.1097/Qad.0000000000002434  0.301
2019 Abrahams MR, Joseph SB, Garrett N, Tyers L, Moeser M, Archin N, Council OD, Matten D, Zhou S, Doolabh D, Anthony C, Goonetilleke N, Karim SA, Margolis DM, Pond SK, et al. The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation. Science Translational Medicine. 11. PMID 31597754 DOI: 10.1126/scitranslmed.aaw5589  0.351
2019 Xu Y, Trumble IM, Warren JA, Clutton G, Abad-Fernandez M, Kirchnerr J, Adimora AA, Deeks SG, Margolis DM, Kuruc JD, Gay CL, Archin NM, Mollan KR, Hudgens M, Goonetilleke N. HIV-Specific T Cell Responses Are Highly Stable on Antiretroviral Therapy. Molecular Therapy. Methods & Clinical Development. 15: 9-17. PMID 31534983 DOI: 10.1016/J.Omtm.2019.07.008  0.31
2019 Garrido C, Tolstrup M, Søgaard OS, Rasmussen TA, Allard B, Soriano-Sarabia N, Archin NM, Margolis DM. In-vivo administration of histone deacetylase inhibitors does not impair natural killer cell function in HIV+ individuals. Aids (London, England). 33: 605-613. PMID 30830886 DOI: 10.1097/QAD.0000000000002112  0.319
2018 Sung JA, Patel S, Clohosey ML, Roesch L, Tripic T, Kuruc JD, Archin N, Hanley PJ, Cruz CR, Goonetilleke N, Eron JJ, Rooney CM, Gay CL, Bollard CM, Margolis DM. HIV-Specific, Ex Vivo Expanded T Cell Therapy: Feasibility, Safety, and Efficacy in ART-Suppressed HIV-Infected Individuals. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 30249388 DOI: 10.1016/j.ymthe.2018.08.015  0.413
2017 Wu G, Swanson M, Talla A, Graham D, Strizki J, Gorman D, Barnard RJ, Blair W, Søgaard OS, Tolstrup M, Østergaard L, Rasmussen TA, Sekaly RP, Archin NM, Margolis DM, et al. HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal. Jci Insight. 2. PMID 28814661 DOI: 10.1172/Jci.Insight.92901  0.33
2017 Sung JA, Sholtis K, Kirchherr J, Kuruc JD, Gay CL, Nordstrom JL, Bollard CM, Archin NM, Margolis DM. Vorinostat Renders the Replication-Competent Latent Reservoir of Human Immunodeficiency Virus (HIV) Vulnerable to Clearance by CD8 T Cells. Ebiomedicine. PMID 28803740 DOI: 10.1016/j.ebiom.2017.07.019  0.446
2017 Gay CL, DeBenedette MA, Tcherepanova IY, Gamble A, Lewis WE, Cope AB, Kuruc JD, McGee KS, Kearney MF, Coffin JM, Archin NM, Hicks CB, Eron JJ, Nicolette CA, Margolis DM. Immunogenicity of AGS-004 Dendritic Cell Therapy in Patients Treated During Acute HIV Infection. Aids Research and Human Retroviruses. PMID 28636433 DOI: 10.1089/aid.2017.0071  0.305
2017 Margolis DM, Archin NM. Proviral Latency, Persistent Human Immunodeficiency Virus Infection, and the Development of Latency Reversing Agents. The Journal of Infectious Diseases. 215: S111-S118. PMID 28520964 DOI: 10.1093/infdis/jiw618  0.362
2017 Bosque A, Nilson KA, Macedo AB, Spivak AM, Archin NM, Van Wagoner RM, Martins LJ, Novis CL, Szaniawski MA, Ireland CM, Margolis DM, Price DH, Planelles V. Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation. Cell Reports. 18: 1324-1334. PMID 28147284 DOI: 10.1016/J.Celrep.2017.01.022  0.31
2016 Lee SK, Zhou S, Baldoni PL, Spielvogel E, Archin NM, Hudgens MG, Margolis DM, Swanstrom R. Quantification of the Latent HIV-1 Reservoir Using Ultra Deep Sequencing and Primer ID In A Viral Outgrowth Assay. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 27683060 DOI: 10.1097/Qai.0000000000001187  0.308
2016 Tsai P, Wu G, Baker CE, Thayer WO, Spagnuolo RA, Sanchez R, Barrett S, Howell B, Margolis D, Hazuda DJ, Archin NM, Garcia JV. In vivo analysis of the effect of panobinostat on cell-associated HIV RNA and DNA levels and latent HIV infection. Retrovirology. 13: 36. PMID 27206407 DOI: 10.1186/S12977-016-0268-7  0.335
2015 Soriano-Sarabia N, Archin NM, Bateson R, Dahl NP, Crooks AM, Kuruc JD, Garrido C, Margolis DM. Peripheral Vγ9Vδ2 T Cells Are a Novel Reservoir of Latent HIV Infection. Plos Pathogens. 11: e1005201. PMID 26473478 DOI: 10.1371/journal.ppat.1005201  0.418
2015 Sung JA, Pickeral J, Liu L, Stanfield-Oakley SA, Lam CK, Garrido C, Pollara J, LaBranche C, Bonsignori M, Moody MA, Yang Y, Parks R, Archin N, Allard B, Kirchherr J, et al. Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells. The Journal of Clinical Investigation. PMID 26413868 DOI: 10.1172/Jci82314  0.373
2015 Crooks AM, Bateson R, Cope AB, Dahl NP, Griggs MK, Kuruc JD, Gay CL, Eron JJ, Margolis DM, Bosch RJ, Archin NM. Precise Quantitation of the Latent HIV-1 Reservoir: Implications for Eradication Strategies. The Journal of Infectious Diseases. PMID 25877550 DOI: 10.1093/infdis/jiv218  0.385
2015 Sung JA, Lam S, Garrido C, Archin N, Rooney CM, Bollard CM, Margolis DM. Expanded cytotoxic T-cell lymphocytes target the latent HIV reservoir. The Journal of Infectious Diseases. 212: 258-63. PMID 25589335 DOI: 10.1093/infdis/jiv022  0.427
2014 Archin NM, Sung JM, Garrido C, Soriano-Sarabia N, Margolis DM. Eradicating HIV-1 infection: seeking to clear a persistent pathogen. Nature Reviews. Microbiology. 12: 750-64. PMID 25402363 DOI: 10.1038/nrmicro3352  0.366
2014 Lam S, Sung J, Cruz C, Castillo-Caro P, Ngo M, Garrido C, Kuruc J, Archin N, Rooney C, Margolis D, Bollard C. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 387-95. PMID 25366030 DOI: 10.1038/mt.2014.207  0.339
2014 Soriano-Sarabia N, Bateson RE, Dahl NP, Crooks AM, Kuruc JD, Margolis DM, Archin NM. Quantitation of replication-competent HIV-1 in populations of resting CD4+ T cells. Journal of Virology. 88: 14070-7. PMID 25253353 DOI: 10.1128/JVI.01900-14  0.402
2014 Denton PW, Long JM, Wietgrefe SW, Sykes C, Spagnuolo RA, Snyder OD, Perkey K, Archin NM, Choudhary SK, Yang K, Hudgens MG, Pastan I, Haase AT, Kashuba AD, Berger EA, et al. Targeted cytotoxic therapy kills persisting HIV infected cells during ART. Plos Pathogens. 10: e1003872. PMID 24415939 DOI: 10.1371/Journal.Ppat.1003872  0.336
2014 Salgado M, Swanson MD, Pohlmeyer CW, Buckheit RW, Wu J, Archin NM, Williams TM, Margolis DM, Siliciano RF, Garcia JV, Blankson JN. HLA-B*57 elite suppressor and chronic progressor HIV-1 isolates replicate vigorously and cause CD4+ T cell depletion in humanized BLT mice. Journal of Virology. 88: 3340-52. PMID 24390323 DOI: 10.1128/Jvi.03380-13  0.383
2013 Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, et al. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. Plos Pathogens. 9: e1003834. PMID 24385908 DOI: 10.1371/Journal.Ppat.1003834  0.335
2013 Honeycutt JB, Wahl A, Archin N, Choudhary S, Margolis D, Garcia JV. HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model. Retrovirology. 10: 121. PMID 24156277 DOI: 10.1186/1742-4690-10-121  0.426
2012 Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, Parker DC, Anderson EM, Kearney MF, Strain MC, Richman DD, Hudgens MG, Bosch RJ, Coffin JM, Eron JJ, et al. Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 487: 482-5. PMID 22837004 DOI: 10.1038/Nature11286  0.322
2012 Banerjee C, Archin N, Michaels D, Belkina AC, Denis GV, Bradner J, Sebastiani P, Margolis DM, Montano M. BET bromodomain inhibition as a novel strategy for reactivation of HIV-1 Journal of Leukocyte Biology. 92: 1147-1154. PMID 22802445 DOI: 10.1189/Jlb.0312165  0.37
2012 Archin NM, Vaidya NK, Kuruc JD, Liberty AL, Wiegand A, Kearney MF, Cohen MS, Coffin JM, Bosch RJ, Gay CL, Eron JJ, Margolis DM, Perelson AS. Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection. Proceedings of the National Academy of Sciences of the United States of America. 109: 9523-8. PMID 22645358 DOI: 10.1073/pnas.1120248109  0.406
2012 Denton PW, Olesen R, Choudhary SK, Archin NM, Wahl A, Swanson MD, Chateau M, Nochi T, Krisko JF, Spagnuolo RA, Margolis DM, Garcia JV. Generation of HIV latency in humanized BLT mice. Journal of Virology. 86: 630-4. PMID 22013053 DOI: 10.1128/Jvi.06120-11  0.453
2012 Choudhary SK, Archin NM, Cheema M, Dahl NP, Garcia JV, Margolis DM. Latent HIV-1 infection of resting CD4⁺ T cells in the humanized Rag2⁻/⁻ γc⁻/⁻ mouse. Journal of Virology. 86: 114-20. PMID 22013038 DOI: 10.1128/JVI.05590-11  0.511
2011 Anderson JA, Archin NM, Ince W, Parker D, Wiegand A, Coffin JM, Kuruc J, Eron J, Swanstrom R, Margolis DM. Clonal sequences recovered from plasma from patients with residual HIV-1 viremia and on intensified antiretroviral therapy are identical to replicating viral RNAs recovered from circulating resting CD4+ T cells. Journal of Virology. 85: 5220-3. PMID 21367910 DOI: 10.1128/Jvi.00284-11  0.336
2010 Archin NM, Cheema M, Parker D, Wiegand A, Bosch RJ, Coffin JM, Eron J, Cohen M, Margolis DM. Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection. Plos One. 5: e9390. PMID 20186346 DOI: 10.1371/journal.pone.0009390  0.376
2009 Keedy KS, Archin NM, Gates AT, Espeseth A, Hazuda DJ, Margolis DM. A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression. Journal of Virology. 83: 4749-56. PMID 19279091 DOI: 10.1128/Jvi.02585-08  0.343
2009 Archin NM, Espeseth A, Parker D, Cheema M, Hazuda D, Margolis DM. Expression of latent HIV induced by the potent HDAC inhibitor suberoylanilide hydroxamic acid. Aids Research and Human Retroviruses. 25: 207-12. PMID 19239360 DOI: 10.1089/aid.2008.0191  0.344
2009 Bowman MC, Archin NM, Margolis DM. Pharmaceutical approaches to eradication of persistent HIV infection. Expert Reviews in Molecular Medicine. 11: e6. PMID 19208267 DOI: 10.1017/S1462399409000970  0.342
2008 Archin NM, Eron JJ, Palmer S, Hartmann-Duff A, Martinson JA, Wiegand A, Bandarenko N, Schmitz JL, Bosch RJ, Landay AL, Coffin JM, Margolis DM. Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells. Aids (London, England). 22: 1131-5. PMID 18525258 DOI: 10.1097/QAD.0b013e3282fd6df4  0.345
2008 Choudhary SK, Archin NM, Margolis DM. Hexamethylbisacetamide and disruption of human immunodeficiency virus type 1 latency in CD4+ T cells Journal of Infectious Diseases. 197: 1162-1170. PMID 18419522 DOI: 10.1086/529525  0.338
2007 Margolis DM, Archin NM. Eliminating persistent HIV infection: getting to the end of the rainbow. The Journal of Infectious Diseases. 195: 1734-6. PMID 17492587 DOI: 10.1086/518254  0.324
2006 Margolis DM, Archin NM. Attacking HIV provirus: Therapeutic strategies to disrupt persistent infection Infectious Disorders - Drug Targets. 6: 369-376. PMID 17168802 DOI: 10.2174/187152606779025824  0.307
2003 Archin NM, van den Boom L, Perelygina L, Hilliard JM, Atherton SS. Delayed spread and reduction in virus titer after anterior chamber inoculation of a recombinant of HSV-1 expressing IL-16. Investigative Ophthalmology & Visual Science. 44: 3066-76. PMID 12824253 DOI: 10.1167/iovs.02-1071  0.593
2002 Archin NM, Atherton SS. Infiltration of T-lymphocytes in the brain after anterior chamber inoculation of a neurovirulent and neuroinvasive strain of HSV-1. Journal of Neuroimmunology. 130: 117-27. PMID 12225894 DOI: 10.1016/S0165-5728(02)00213-8  0.617
2002 Archin NM, Atherton SS. Rapid spread of a neurovirulent strain of HSV-1 through the CNS of BALB/c mice following anterior chamber inoculation. Journal of Neurovirology. 8: 122-35. PMID 11935464 DOI: 10.1080/13550280290049570  0.58
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