James F. Howard, MD - Publications

Affiliations: 
1979- Neurology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
neuromuscular junction, myasthenia gravis, complement inhibition
Website:
https://www.med.unc.edu/neurology/directory/james-f-howard-jr-md/

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mantegazza R, O'Brien FL, Yountz M, Howard JF. Consistent improvement with eculizumab across muscle groups in myasthenia gravis. Annals of Clinical and Translational Neurology. PMID 32700461 DOI: 10.1002/Acn3.51121  0.407
2020 Areson DG, Filer WG, Harris MG, Howard JF, Shuping LT, Traub R. Accuracy of the Scratch Collapse Test for Carpal Tunnel Syndrome in Comparison With Electrodiagnostic Studies. Hand (New York, N.Y.). 1558944719895786. PMID 32698624 DOI: 10.1177/1558944719895786  0.313
2020 Albazli K, Kaminski HJ, Howard JF. Complement Inhibitor Therapy for Myasthenia Gravis. Frontiers in Immunology. 11: 917. PMID 32582144 DOI: 10.3389/Fimmu.2020.00917  0.339
2020 Jacob S, Murai H, Utsugisawa K, Nowak RJ, Wiendl H, Fujita KP, O'Brien F, Howard JF. Response to eculizumab in patients with myasthenia gravis recently treated with chronic IVIg: a subgroup analysis of REGAIN and its open-label extension study. Therapeutic Advances in Neurological Disorders. 13: 1756286420911784. PMID 32426038 DOI: 10.1177/1756286420911784  0.335
2020 Vissing J, Jacob S, Fujita KP, O'Brien F, Howard JF. 'Minimal symptom expression' in patients with acetylcholine receptor antibody-positive refractory generalized myasthenia gravis treated with eculizumab. Journal of Neurology. PMID 32189108 DOI: 10.1007/S00415-020-09770-Y  0.3
2020 Howard JF, Nowak RJ, Wolfe GI, Freimer ML, Vu TH, Hinton JL, Benatar M, Duda PW, MacDougall JE, Farzaneh-Far R, Kaminski HJ, Barohn R, Dimachkie M, Pasnoor M, ... ... Howard JF, et al. Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis: Results of a Phase 2 Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial. Jama Neurology. PMID 32065623 DOI: 10.1001/Jamaneurol.2019.5125  0.331
2019 Howard JF, Bril V, Burns TM, Mantegazza R, Bilinska M, Szczudlik A, Beydoun S, Garrido FJRR, Piehl F, Rottoli M, Van Damme P, Vu T, Evoli A, Freimer M, Mozaffar T, et al. Randomized phase 2 study of FcRn antagonist efgartigimod in generalized myasthenia gravis. Neurology. PMID 31118245 DOI: 10.1212/Wnl.0000000000007600  0.3
2019 Andersen H, Mantegazza R, Wang JJ, O'Brien F, Patra K, Howard JF. Eculizumab improves fatigue in refractory generalized myasthenia gravis. Quality of Life Research : An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. PMID 30905021 DOI: 10.1007/S11136-019-02148-2  0.303
2018 Clifford KM, Hobson-Webb LD, Benatar M, Burns TM, Barnett C, Silvestri NJ, Howard JF, Visser A, Crum BA, Nowak R, Beekman R, Kumar A, Ruzhansky K, Chen IA, Pulley MT, et al. Thymectomy may not be associated with clinical improvement in MuSK myasthenia gravis. Muscle & Nerve. PMID 30575980 DOI: 10.1002/Mus.26404  0.394
2018 Li Y, Guptill JT, Russo MA, Massey JM, Juel VC, Hobson-Webb LD, Howard JF, Chopra M, Liu W, Yi JS. Tacrolimus inhibits Th1 and Th17 responses in MuSK-antibody positive myasthenia gravis patients. Experimental Neurology. PMID 30472069 DOI: 10.1016/J.Expneurol.2018.11.006  0.304
2018 Moore CJ, Caughey MC, Meyer DO, Emmett R, Jacobs C, Chopra M, Howard JF, Gallippi CM. In Vivo Viscoelastic Response (VisR) Ultrasound for Characterizing Mechanical Anisotropy in Lower-Limb Skeletal Muscles of Boys with and without Duchenne Muscular Dystrophy. Ultrasound in Medicine & Biology. PMID 30174231 DOI: 10.1016/J.Ultrasmedbio.2018.07.004  0.398
2018 Howard JF, O'Brien F, Wang JJ. Distinct representation of muscle weakness in QMG and MG-ADL - Authors' reply. The Lancet. Neurology. 17: 205-206. PMID 29452680 DOI: 10.1016/S1474-4422(18)30036-X  0.398
2017 Howard JF. Myasthenia gravis: the role of complement at the neuromuscular junction. Annals of the New York Academy of Sciences. PMID 29266249 DOI: 10.1111/Nyas.13522  0.409
2017 Howard JF, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Muppidi S, Nowak RJ, O'Brien F, Wang JJ, Mantegazza R, et al. Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study. The Lancet. Neurology. PMID 29066163 DOI: 10.1016/S1474-4422(17)30369-1  0.31
2017 Benatar M, Howard JF, Barohn R, Wolfe GI, Cutter G. Learning from the past: reflections on recently completed myasthenia gravis trials. Annals of the New York Academy of Sciences. PMID 29064567 DOI: 10.1111/Nyas.13501  0.317
2017 Hehir MK, Hobson-Webb LD, Benatar M, Barnett C, Silvestri NJ, Howard JF, Howard D, Visser A, Crum BA, Nowak R, Beekman R, Kumar A, Ruzhansky K, Chen IA, Pulley MT, et al. Rituximab as treatment for anti-MuSK myasthenia gravis: Multicenter blinded prospective review. Neurology. PMID 28801338 DOI: 10.1212/Wnl.0000000000004341  0.378
2017 Guglieri M, Bushby K, McDermott MP, Hart KA, Tawil R, Martens WB, Herr BE, McColl E, Wilkinson J, Kirschner J, King WM, Eagle M, Brown MW, Willis T, Hirtz D, ... ... Howard JF, et al. Developing standardized corticosteroid treatment for Duchenne muscular dystrophy. Contemporary Clinical Trials. PMID 28450193 DOI: 10.1016/J.Cct.2017.04.008  0.308
2017 Richards J, Howard JF. Seronegative myasthenia gravis associated with malignant thymoma. Neuromuscular Disorders : Nmd. PMID 28238572 DOI: 10.1016/J.Nmd.2017.01.023  0.362
2016 Howard JF, Freimer M, O'Brien F, Wang JJ, Collins SR, Kissel JT, Herbelin L, McVey AL, Dimachkie MM, Pasnoor M, Lu D, Waltz A, Chaudhry V, Corse A, et al. QMG and MG-ADL Correlations: Study of Eculizumab Treatment of Myasthenia Gravis. Muscle & Nerve. PMID 28010051 DOI: 10.1002/Mus.25529  0.308
2016 Guptill JT, Juel VC, Massey JM, Anderson AC, Chopra M, Yi JS, Esfandiari E, Buchanan T, Smith B, Atherfold P, Jones E, Howard JF. Effect of therapeutic plasma exchange on immunoglobulins in myasthenia gravis. Autoimmunity. 1-8. PMID 27684107 DOI: 10.1080/08916934.2016.1214823  0.336
2016 Pasnoor M, He J, Herbelin L, Burns TM, Nations S, Bril V, Wang AK, Elsheikh BH, Kissel JT, Saperstein D, Shaibani JA, Jackson C, Swenson A, Howard JF, Goyal N, et al. A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis. Neurology. PMID 27306628 DOI: 10.1212/Wnl.0000000000002795  0.311
2015 Beltran Papsdorf T, Howard JF, Chahin N. Late-onset Becker muscular dystrophy: Refining the clinical features and electrophysiological findings. Muscle & Nerve. PMID 26179421 DOI: 10.1002/Mus.24773  0.409
2015 Fan Z, Kocis K, Valley R, Howard J, Chopra M, Chen Y, An H, Lin W, Muenzer J, Powers W. High-pressure Transvenous Perfusion of the Upper Extremity in Human Muscular Dystrophy: A Safety Study with 0.9% Saline. Human Gene Therapy. PMID 25953425 DOI: 10.1089/Hum.2015.023  0.356
2015 Guptill JT, Yi JS, Sanders DB, Guidon AC, Juel VC, Massey JM, Howard JF, Scuderi F, Bartoccioni E, Evoli A, Weinhold KJ. Characterization of B cells in muscle-specific kinase antibody myasthenia gravis. Neurology® Neuroimmunology & Neuroinflammation. 2: e77. PMID 25745635 DOI: 10.1212/Nxi.0000000000000077  0.379
2015 Renton AE, Pliner HA, Provenzano C, Evoli A, Ricciardi R, Nalls MA, Marangi G, Abramzon Y, Arepalli S, Chong S, Hernandez DG, Johnson JO, Bartoccioni E, Scuderi F, Maestri M, ... ... Howard JF, et al. A genome-wide association study of myasthenia gravis. Jama Neurology. 72: 396-404. PMID 25643325 DOI: 10.1001/Jamaneurol.2014.4103  0.338
2014 Beltran Papsdorf TB, Howard JF, Chahin N. Pearls & Oy-sters: clues to the diagnosis of adult-onset acid maltase deficiency. Neurology. 82: e73-5. PMID 24590251 DOI: 10.1212/Wnl.0000000000000163  0.376
2013 Howard JF, Barohn RJ, Cutter GR, Freimer M, Juel VC, Mozaffar T, Mellion ML, Benatar MG, Farrugia ME, Wang JJ, Malhotra SS, Kissel JT. A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis. Muscle & Nerve. 48: 76-84. PMID 23512355 DOI: 10.1002/Mus.23839  0.311
2012 Kornegay JN, Childers MK, Bogan DJ, Bogan JR, Nghiem P, Wang J, Fan Z, Howard JF, Schatzberg SJ, Dow JL, Grange RW, Styner MA, Hoffman EP, Wagner KR. The paradox of muscle hypertrophy in muscular dystrophy. Physical Medicine and Rehabilitation Clinics of North America. 23: 149-72, xii. PMID 22239881 DOI: 10.1016/J.Pmr.2011.11.014  0.42
2012 Kornegay JN, Bogan JR, Bogan DJ, Childers MK, Li J, Nghiem P, Detwiler DA, Larsen CA, Grange RW, Bhavaraju-Sanka RK, Tou S, Keene BP, Howard JF, Wang J, Fan Z, et al. Canine models of Duchenne muscular dystrophy and their use in therapeutic strategies. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 85-108. PMID 22218699 DOI: 10.1007/S00335-011-9382-Y  0.715
2012 Fan Z, Kocis K, Valley R, Howard JF, Chopra M, An H, Lin W, Muenzer J, Powers W. Safety and feasibility of high-pressure transvenous limb perfusion with 0.9% saline in human muscular dystrophy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 456-61. PMID 21772257 DOI: 10.1038/Mt.2011.137  0.389
2012 Howard J, Barohn R, Freimer M, Juel V, Mozaffar T, Mellion M, Benatar M, Farrugia M, Kissel J. Randomized, Double-Blind, Placebo-Controlled, Crossover, Multicenter, Phase II Study of Eculizumab in Patients with Refractory Generalized Myasthenia Gravis (gMG) (S35.004) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S35.004  0.361
2010 Kornegay JN, Li J, Bogan JR, Bogan DJ, Chen C, Zheng H, Wang B, Qiao C, Howard JF, Xiao X. Widespread muscle expression of an AAV9 human mini-dystrophin vector after intravenous injection in neonatal dystrophin-deficient dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 18: 1501-8. PMID 20517298 DOI: 10.1038/Mt.2010.94  0.407
2009 Donofrio PD, Berger A, Brannagan TH, Bromberg MB, Howard JF, Latov N, Quick A, Tandan R. Consensus statement: the use of intravenous immunoglobulin in the treatment of neuromuscular conditions report of the AANEM ad hoc committee. Muscle & Nerve. 40: 890-900. PMID 19768755 DOI: 10.1002/Mus.21433  0.319
2009 England JD, Gronseth GS, Franklin G, Carter GT, Kinsella LJ, Cohen JA, Asbury AK, Szigeti K, Lupski JR, Latov N, Lewis RA, Low PA, Fisher MA, Herrmann D, Howard JF, et al. Evaluation of distal symmetric polyneuropathy: the role of autonomic testing, nerve biopsy, and skin biopsy (an evidence-based review). Muscle & Nerve. 39: 106-15. PMID 19086069 DOI: 10.1002/Mus.21227  0.309
2008 Howard JF, Sanders DB. Chapter 12 Neurotoxicology of neuromuscular transmission. Handbook of Clinical Neurology. 91: 369-400. PMID 18631850 DOI: 10.1016/S0072-9752(07)01512-6  0.327
2005 Galano HR, Olby NJ, Howard JF, Shelton GD. Myokymia and neuromyotonia in a cat. Journal of the American Veterinary Medical Association. 227: 1608-12, 1591. PMID 16313038 DOI: 10.2460/Javma.2005.227.1608  0.408
2001 Latov N, Chaudhry V, Koski CL, Lisak RP, Apatoff BR, Hahn AF, Howard JF. Use of intravenous gamma globulins in neuroimmunologic diseases. The Journal of Allergy and Clinical Immunology. 108: S126-32. PMID 11586280 DOI: 10.1067/Mai.2001.118300  0.369
2001 Navaneetham D, Penn AS, Howard JF, Conti-Fine BM. Human thymuses express incomplete sets of muscle acetylcholine receptor subunit transcripts that seldom include the delta subunit. Muscle & Nerve. 24: 203-10. PMID 11180203 DOI: 10.1002/1097-4598(200102)24:2<203::Aid-Mus50>3.0.Co;2-F  0.321
2000 Wang ZY, Diethelm-Okita B, Okita DK, Kaminski HJ, Howard JF, Conti-Fine BM. T cell recognition of muscle acetylcholine receptor in ocular myasthenia gravis. Journal of Neuroimmunology. 108: 29-39. PMID 10900334 DOI: 10.1016/S0165-5728(00)00250-2  0.361
1998 Navaneetham D, Penn AS, Howard JF, Conti-Fine BM. TCR-Vbeta usage in the thymus and blood of myasthenia gravis patients. Journal of Autoimmunity. 11: 621-33. PMID 9878084 DOI: 10.1006/Jaut.1998.0246  0.334
1998 Howard JF. Intravenous immunoglobulin for the treatment of acquired myasthenia gravis. Neurology. 51: S30-6. PMID 9851728 DOI: 10.1212/Wnl.51.6_Suppl_5.S30  0.325
1998 Wang ZY, Okita DK, Howard J, Conti-Fine BM. T-cell recognition of muscle acetylcholine receptor subunits in generalized and ocular myasthenia gravis. Neurology. 50: 1045-54. PMID 9566393 DOI: 10.1212/Wnl.50.4.1045  0.389
1997 Patton LL, Howard JF. Myasthenia gravis: dental treatment considerations. Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry For the Handicapped, and the American Society For Geriatric Dentistry. 17: 25-32. PMID 9582706 DOI: 10.1111/J.1754-4505.1997.Tb00532.X  0.374
1997 Wang ZY, Okita DK, Howard J, Conti-Fine BM. Th1 epitope repertoire on the alpha subunit of human muscle acetylcholine receptor in myasthenia gravis. Neurology. 48: 1643-53. PMID 9191781 DOI: 10.1212/Wnl.48.6.1643  0.322
1996 Jaradeh S, D'Cruz O, Howard JF, Haberkamp TJ, Konkol RJ. Mobius syndrome: electrophysiologic studies in seven cases. Muscle & Nerve. 19: 1148-53. PMID 8761272 DOI: 10.1002/(Sici)1097-4598(199609)19:9<1148::Aid-Mus11>3.0.Co;2-R  0.385
1994 Howard JF, Sanders DB, Massey JM. The electrodiagnosis of myasthenia gravis and the Lambert-Eaton myasthenic syndrome. Neurologic Clinics. 12: 305-30. PMID 8041344 DOI: 10.1016/S0733-8619(18)30099-9  0.304
1994 Andrews PI, Massey JM, Howard JF, Sanders DB. Race, sex, and puberty influence onset, severity, and outcome in juvenile myasthenia gravis. Neurology. 44: 1208-14. PMID 8035917 DOI: 10.1212/Wnl.44.7.1208  0.305
1993 Manfredi AA, Protti MP, Dalton MW, Howard JF, Conti-Tronconi BM. T helper cell recognition of muscle acetylcholine receptor in myasthenia gravis. Epitopes on the gamma and delta subunits. The Journal of Clinical Investigation. 92: 1055-67. PMID 7688757 DOI: 10.1172/Jci116610  0.387
1993 Hopkins AL, Howard JF, Wheeler SJ, Kornegay JN. Stimulated single fibre electromyography in normal dogs Journal of Small Animal Practice. 34: 271-276. DOI: 10.1111/J.1748-5827.1993.Tb02685.X  0.404
1992 Protti MP, Manfredi AA, Wu XD, Moiola L, Dalton MW, Howard JF, Conti-Tronconi BM. Myasthenia gravis. CD4+ T epitopes on the embryonic gamma subunit of human muscle acetylcholine receptor. The Journal of Clinical Investigation. 90: 1558-67. PMID 1383275 DOI: 10.1172/Jci116024  0.38
1991 Protti MP, Manfredi AA, Howard JF, Conti-Tronconi BM. T cells in myasthenia gravis specific for embryonic acetylcholine receptor. Neurology. 41: 1809-14. PMID 1682852 DOI: 10.1212/Wnl.41.11.1809  0.418
1989 Massey JM, Sanders DB, Howard JF. The effect of cholinesterase inhibitors of SFEMG in myasthenia gravis. Muscle & Nerve. 12: 154-5. PMID 2540433 DOI: 10.1002/Mus.880120211  0.326
1988 Sanders DB, Howard JF. Thymoma without myasthenia gravis: electrophysiological study after thymectomy. Journal of Neurology, Neurosurgery, and Psychiatry. 51: 160-1. PMID 3351526 DOI: 10.1136/Jnnp.51.1.160-A  0.308
1986 Sanders DB, Howard JF. AAEE minimonograph #25: Single-fiber electromyography in myasthenia gravis. Muscle & Nerve. 9: 809-19. PMID 3785290 DOI: 10.1002/Mus.880090904  0.497
1981 Sanders DB, Kim YI, Howard JF, Johns TR, Muller WH. Intercostal muscle biopsy studies in myasthenia gravis: clinical correlations and the direct effects of drugs and myasthenic serum. Annals of the New York Academy of Sciences. 377: 544-66. PMID 6280565 DOI: 10.1111/J.1749-6632.1981.Tb33758.X  0.733
1980 Howard JF, Sanders DB. Passive transfer of human myasthenia gravis to rats: 1. Electrophysiology of the developing neuromuscular block. Neurology. 30: 760-4. PMID 7190241 DOI: 10.1212/Wnl.30.7.760  0.353
1980 Sanders DB, Kim YI, Howard JF, Goetsch CA. Eaton-Lambert syndrome: a clinical and electrophysiological study of a patient treated with 4-aminopyridine. Journal of Neurology, Neurosurgery, and Psychiatry. 43: 978-85. PMID 6255102 DOI: 10.1136/Jnnp.43.11.978  0.382
1979 Sanders DB, Howard JF, Johns TR. Single-fiber electromyography in myasthenia gravis. Neurology. 29: 68-76. PMID 218146 DOI: 10.1212/Wnl.29.1.68  0.723
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