Year |
Citation |
Score |
2011 |
Schalk-Hihi C, Schubert C, Alexander R, Bayoumy S, Clemente JC, Deckman I, DesJarlais RL, Dzordzorme KC, Flores CM, Grasberger B, Kranz JK, Lewandowski F, Liu L, Ma H, Maguire D, et al. Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 Ã… resolution. Protein Science : a Publication of the Protein Society. 20: 670-83. PMID 21308848 DOI: 10.1002/Pro.596 |
0.434 |
|
2008 |
Janka L, Clemente J, Vaiana N, Sparatore A, Romeo S, Dunn BM. Targeting the plasmepsin 4 orthologs of Plasmodium sp. with "double drug" inhibitors. Protein and Peptide Letters. 15: 868-73. PMID 18991760 DOI: 10.2174/092986608785849218 |
0.541 |
|
2008 |
Clemente JC, Robbins A, Graña P, Paleo MR, Correa JF, Villaverde MC, Sardina FJ, Govindasamy L, Agbandje-McKenna M, McKenna R, Dunn BM, Sussman F. Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. Journal of Medicinal Chemistry. 51: 852-60. PMID 18215016 DOI: 10.1021/Jm701170F |
0.633 |
|
2007 |
Moose RE, Clemente JC, Jackson LR, Ngo M, Wooten K, Chang R, Bennett A, Chakraborty S, Yowell CA, Dame JB, Agbandje-McKenna M, Dunn BM. Analysis of binding interactions of pepsin inhibitor-3 to mammalian and malarial aspartic proteases. Biochemistry. 46: 14198-205. PMID 18004881 DOI: 10.1021/Bi7014844 |
0.709 |
|
2006 |
Gutiérrez-de-Terán H, Nervall M, Dunn BM, Clemente JC, Aqvist J. Computational analysis of plasmepsin IV bound to an allophenylnorstatine inhibitor. Febs Letters. 580: 5910-6. PMID 17045991 DOI: 10.1016/J.Febslet.2006.09.057 |
0.664 |
|
2006 |
Clemente JC, Coman RM, Thiaville MM, Janka LK, Jeung JA, Nukoolkarn S, Govindasamy L, Agbandje-McKenna M, McKenna R, Leelamanit W, Goodenow MM, Dunn BM. Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir. Biochemistry. 45: 5468-77. PMID 16634628 DOI: 10.1021/Bi051886S |
0.774 |
|
2006 |
Clemente JC, Govindasamy L, Madabushi A, Fisher SZ, Moose RE, Yowell CA, Hidaka K, Kimura T, Hayashi Y, Kiso Y, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Structure of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae bound to an allophenylnorstatine-based inhibitor. Acta Crystallographica. Section D, Biological Crystallography. 62: 246-52. PMID 16510971 DOI: 10.1107/S0907444905041260 |
0.693 |
|
2006 |
Ersmark K, Nervall M, Gutiérrez-de-Terán H, Hamelink E, Janka LK, Clemente JC, Dunn BM, Gogoll A, Samuelsson B, Qvist J, Hallberg A. Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV. Bioorganic & Medicinal Chemistry. 14: 2197-208. PMID 16307884 DOI: 10.1016/J.Bmc.2005.11.003 |
0.591 |
|
2005 |
Madabushi A, Chakraborty S, Fisher SZ, Clemente JC, Yowell C, Agbandje-McKenna M, Dame JB, Dunn BM, McKenna R. Crystallization and preliminary X-ray analysis of the aspartic protease plasmepsin 4 from the malarial parasite Plasmodium malariae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 228-31. PMID 16511002 DOI: 10.1107/S1744309105001405 |
0.537 |
|
2005 |
Ersmark K, Nervall M, Hamelink E, Janka LK, Clemente JC, Dunn BM, Blackman MJ, Samuelsson B, Aqvist J, Hallberg A. Synthesis of malarial plasmepsin inhibitors and prediction of binding modes by molecular dynamics simulations. Journal of Medicinal Chemistry. 48: 6090-106. PMID 16162010 DOI: 10.1021/Jm050463L |
0.588 |
|
2005 |
Pettit SC, Clemente JC, Jeung JA, Dunn BM, Kaplan AH. Ordered processing of the human immunodeficiency virus type 1 GagPol precursor is influenced by the context of the embedded viral protease. Journal of Virology. 79: 10601-7. PMID 16051852 DOI: 10.1128/Jvi.79.16.10601-10607.2005 |
0.539 |
|
2005 |
Castanheira P, Samyn B, Sergeant K, Clemente JC, Dunn BM, Pires E, Van Beeumen J, Faro C. Activation, proteolytic processing, and peptide specificity of recombinant cardosin A. The Journal of Biological Chemistry. 280: 13047-54. PMID 15677463 DOI: 10.1074/Jbc.M412076200 |
0.574 |
|
2004 |
Clemente JC, Moose RE, Hemrajani R, Whitford LR, Govindasamy L, Reutzel R, McKenna R, Agbandje-McKenna M, Goodenow MM, Dunn BM. Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease. Biochemistry. 43: 12141-51. PMID 15379553 DOI: 10.1021/bi049459m |
0.692 |
|
2004 |
Wlodawer A, Li M, Gustchina A, Oyama H, Oda K, Beyer BB, Clemente J, Dunn BM. Two inhibitor molecules bound in the active site of Pseudomonas sedolisin: a model for the bi-product complex following cleavage of a peptide substrate. Biochemical and Biophysical Research Communications. 314: 638-45. PMID 14733955 DOI: 10.1016/J.Bbrc.2003.12.130 |
0.7 |
|
2003 |
Clemente JC, Hemrajani R, Blum LE, Goodenow MM, Dunn BM. Secondary mutations M36I and A71V in the human immunodeficiency virus type 1 protease can provide an advantage for the emergence of the primary mutation D30N. Biochemistry. 42: 15029-35. PMID 14690411 DOI: 10.1021/Bi035701Y |
0.668 |
|
Show low-probability matches. |