M Imad Damaj - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
Area:
Pharmacology, Public Health

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Year Citation  Score
2016 Ondachi PW, Castro AH, Sherman B, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, Nicotinic Acetylcholine Receptor Binding, In Vitro and In Vivo Pharmacological Properties of 2'-Fluoro-(substituted thiophenyl)deschloroepibatidine Analogs. Acs Chemical Neuroscience. PMID 27726337 DOI: 10.1021/acschemneuro.6b00252  0.36
2016 Alsharari SD, Bagdas D, Akbarali HI, Lichtman PA, Raborn ES, Cabral GA, Carroll FI, McGee EA, Damaj MI. Sex differences and drug dose influence the role of the α7 nicotinic acetylcholine receptor in the Mouse Dextran Sodium Sulfate-Induced Colitis Model. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 27639096 DOI: 10.1093/ntr/ntw245  0.48
2016 Enga RM, Jackson A, Damaj MI, Beardsley PM. Oxycodone physical dependence and its oral self-administration in C57BL/6J mice. European Journal of Pharmacology. PMID 27393461 DOI: 10.1016/j.ejphar.2016.07.006  0.48
2016 Ondachi PW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, Nicotinic Acetylcholine Binding, In Vitro and In Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogs. Acs Chemical Neuroscience. PMID 27166021 DOI: 10.1021/acschemneuro.6b00107  0.48
2016 Gade AR, Kang M, Khan F, Grider JR, Damaj MI, Dewey WL, Akbarali HI. Enhanced sensitivity of α3β4 nicotinic receptors in enteric neurons after chronic morphine: implication for opioid-induced constipation. The Journal of Pharmacology and Experimental Therapeutics. PMID 27068812 DOI: 10.1124/jpet.116.233304  0.36
2016 Wilkerson JL, Ghosh S, Bagdas D, Mason BL, Crowe MS, Hsu KL, Wise LE, Kinsey SG, Damaj MI, Cravatt BF, Lichtman AH. Diacylglycerol lipase beta inhibition reverses nociceptive behavior in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology. PMID 26915789 DOI: 10.1111/bph.13469  0.48
2016 Alajaji M, Lazenka MF, Kota D, Wise LE, YOUnis RM, Carroll FI, Levine A, Selley DE, Sim-Selley LJ, Damaj MI. Early adolescent nicotine exposure affects later-life cocaine reward in mice. Neuropharmacology. PMID 26808314 DOI: 10.1016/j.neuropharm.2016.01.032  0.48
2016 Bagdas D, Muldoon PP, AlSharari S, Carroll FI, Negus SS, Damaj MI. Expression and pharmacological modulation of visceral pain-induced conditioned place aversion in mice. Neuropharmacology. 102: 236-43. PMID 26639043 DOI: 10.1016/j.neuropharm.2015.11.024  0.36
2015 Alsharari SD, King JR, Nordman JC, Muldoon PP, Jackson A, Zhu AZ, Tyndale RF, Kabbani N, Damaj MI. Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice. Plos One. 10: e0137070. PMID 26355604 DOI: 10.1371/journal.pone.0137070  0.48
2015 Jackson KJ, Muldoon PP, Walters C, Damaj MI. Neuronal calcium/calmodulin-dependent protein kinase II mediates nicotine reward in the conditioned place preference test in mice. Behavioural Pharmacology. PMID 26292186 DOI: 10.1097/FBP.0000000000000189  0.48
2015 Bagdas D, Targowska-Duda KM, López JJ, Perez EG, Arias HR, Damaj MI. The Antinociceptive and Antiinflammatory Properties of 3-furan-2-yl-N-p-tolyl-acrylamide, a Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptors in Mice. Anesthesia and Analgesia. 121: 1369-77. PMID 26280585 DOI: 10.1213/ANE.0000000000000902  0.36
2015 Ondachi PW, Ye Z, Castro AH, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3'-(substituted pyridinyl)-deschloroepibatidine analogs. Bioorganic & Medicinal Chemistry. PMID 26233800 DOI: 10.1016/j.bmc.2015.07.021  0.48
2015 Jackson KJ, Jackson A, Ivy Carroll F, Damaj MI. Effects of orally-bioavailable short-acting kappa opioid receptor-selective antagonist LY2456302 on nicotine withdrawal in mice. Neuropharmacology. PMID 26044637 DOI: 10.1016/j.neuropharm.2015.05.023  0.48
2015 Bagdas D, AlSharari SD, Freitas K, Tracy M, Damaj MI. The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain. Biochemical Pharmacology. 97: 590-600. PMID 25931144 DOI: 10.1016/j.bcp.2015.04.013  0.48
2015 Carroll FI, Navarro HA, Mascarella SW, Castro AH, Luetje CW, Wageman CR, Marks MJ, Jackson A, Damaj MI. In Vitro and in Vivo Neuronal Nicotinic Receptor Properties of (+)- and (-)-Pyrido[3,4]homotropane [(+)- and (-)-PHT]: (+)-PHT Is a Potent and Selective Full Agonist at α6β2 Containing Neuronal Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience. 6: 920-6. PMID 25891987 DOI: 10.1021/acschemneuro.5b00077  0.48
2015 Malcolm E, Carroll FI, Blough B, Damaj MI, Shoaib M. Examination of the metabolite hydroxybupropion in the reinforcing and aversive stimulus effects of nicotine in rats. Psychopharmacology. 232: 2763-71. PMID 25761841 DOI: 10.1007/s00213-015-3908-z  0.36
2015 Mannangatti P, NarasimhaNaidu K, Damaj MI, Ramamoorthy S, Jayanthi LD. A Role for p38 Mitogen-activated Protein Kinase-mediated Threonine 30-dependent Norepinephrine Transporter Regulation in Cocaine Sensitization and Conditioned Place Preference. The Journal of Biological Chemistry. 290: 10814-27. PMID 25724654 DOI: 10.1074/jbc.M114.612192  0.48
2015 Papke RL, Bagdas D, Kulkarni AR, Gould T, AlSharari SD, Thakur GA, Damaj MI. The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor. Neuropharmacology. 91: 34-42. PMID 25497451 DOI: 10.1016/j.neuropharm.2014.12.002  0.48
2015 Gamage TF, Ignatowska-Jankowska BM, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH. Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. Drug and Alcohol Dependence. 146: 7-16. PMID 25479915 DOI: 10.1016/j.drugalcdep.2014.11.015  0.48
2015 Jackson KJ, Muldoon PP, De Biasi M, Damaj MI. New mechanisms and perspectives in nicotine withdrawal. Neuropharmacology. 96: 223-34. PMID 25433149 DOI: 10.1016/j.neuropharm.2014.11.009  0.48
2015 Muldoon PP, Chen J, Harenza JL, Abdullah RA, Sim-Selley LJ, Cravatt BF, Miles MF, Chen X, Lichtman AH, Damaj MI. Inhibition of monoacylglycerol lipase reduces nicotine withdrawal. British Journal of Pharmacology. 172: 869-82. PMID 25258021 DOI: 10.1111/bph.12948  0.48
2015 Sanjakdar SS, Maldoon PP, Marks MJ, Brunzell DH, Maskos U, McIntosh JM, Bowers MS, Damaj MI. Differential roles of α6β2* and α4β2* neuronal nicotinic receptors in nicotine- and cocaine-conditioned reward in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 350-60. PMID 25035086 DOI: 10.1038/npp.2014.177  0.48
2014 Bagdas D, Muldoon PP, Zhu AZ, Tyndale RF, Damaj MI. Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice. Neuropharmacology. 85: 67-72. PMID 24859605 DOI: 10.1016/j.neuropharm.2014.05.006  0.48
2014 Muldoon PP, Jackson KJ, Perez E, Harenza JL, Molas S, Rais B, Anwar H, Zaveri NT, Maldonado R, Maskos U, McIntosh JM, Dierssen M, Miles MF, Chen X, De Biasi M, ... Damaj MI, et al. The α3β4* nicotinic ACh receptor subtype mediates physical dependence to morphine: mouse and human studies. British Journal of Pharmacology. 171: 3845-57. PMID 24750073 DOI: 10.1111/bph.12741  0.48
2014 Carroll FI, Blough BE, Mascarella SW, Navarro HA, Lukas RJ, Damaj MI. Bupropion and bupropion analogs as treatments for CNS disorders. Advances in Pharmacology (San Diego, Calif.). 69: 177-216. PMID 24484978 DOI: 10.1016/B978-0-12-420118-7.00005-6  0.48
2014 Ondachi PW, Castro AH, Bartkowiak JM, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 2'-fluoro-3'-(substituted pyridinyl)-7-deschloroepibatidine analogues. Journal of Medicinal Chemistry. 57: 836-48. PMID 24428686 DOI: 10.1021/jm401602p  0.48
2014 Harenza JL, Muldoon PP, De Biasi M, Damaj MI, Miles MF. Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice. Genes, Brain, and Behavior. 13: 213-25. PMID 24289814 DOI: 10.1111/gbb.12113  0.48
2014 Nordman JC, Muldoon P, Clark S, Damaj MI, Kabbani N. The α4 nicotinic receptor promotes CD4+ T-cell proliferation and a helper T-cell immune response. Molecular Pharmacology. 85: 50-61. PMID 24107512 DOI: 10.1124/mol.113.088484  0.48
2014 Alsharari SD, Siu EC, Tyndale RF, Damaj MI. Pharmacokinetic and pharmacodynamics studies of nicotine after oral administration in mice: effects of methoxsalen, a CYP2A5/6 inhibitor. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 16: 18-25. PMID 23884323 DOI: 10.1093/ntr/ntt105  0.48
2013 Jackson KJ, Damaj MI. Calcium/calmodulin-dependent protein kinase IV mediates acute nicotine-induced antinociception in acute thermal pain tests. Behavioural Pharmacology. 24: 689-92. PMID 24196027 DOI: 10.1097/FBP.0000000000000005  0.48
2013 AlSharari SD, Freitas K, Damaj MI. Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: Studies in transgenic mice Biochemical Pharmacology. 86: 1201-1207. PMID 23811428 DOI: 10.1016/j.bcp.2013.06.018  0.48
2013 Jackson KJ, Wang JB, Barbier E, Damaj MI, Chen X. The histidine triad nucleotide binding 1 protein is involved in nicotine reward and physical nicotine withdrawal in mice. Neuroscience Letters. 550: 129-33. PMID 23810802 DOI: 10.1016/j.neulet.2013.06.027  0.48
2013 Ignatowska-Jankowska BM, Muldoon PP, Lichtman AH, Damaj MI. The cannabinoid CB2 receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice. Psychopharmacology. 229: 591-601. PMID 23652588 DOI: 10.1007/s00213-013-3117-6  0.48
2013 Alajaji M, Bowers MS, Knackstedt L, Damaj MI. Effects of the beta-lactam antibiotic ceftriaxone on nicotine withdrawal and nicotine-induced reinstatement of preference in mice. Psychopharmacology. 228: 419-26. PMID 23503685 DOI: 10.1007/s00213-013-3047-3  0.48
2013 Jackson KJ, Sanjakdar SS, Muldoon PP, McIntosh JM, Damaj MI. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse. Neuropharmacology. 70: 228-35. PMID 23416040 DOI: 10.1016/j.neuropharm.2013.01.017  0.48
2013 Kendler KS, Myers J, Damaj MI, Chen X. Early smoking onset and risk for subsequent nicotine dependence: a monozygotic co-twin control study. The American Journal of Psychiatry. 170: 408-13. PMID 23318372 DOI: 10.1176/appi.ajp.2012.12030321  0.48
2013 Freitas K, Carroll FI, Damaj MI. The antinociceptive effects of nicotinic receptors α7-positive allosteric modulators in murine acute and tonic pain models. The Journal of Pharmacology and Experimental Therapeutics. 344: 264-75. PMID 23115222 DOI: 10.1124/jpet.112.197871  0.48
2013 AlSharari SD, Akbarali HI, Abdullah RA, Shahab O, Auttachoat W, Ferreira GA, White KL, Lichtman AH, Cabral GA, Damaj MI. Novel insights on the effect of nicotine in a murine colitis model. The Journal of Pharmacology and Experimental Therapeutics. 344: 207-17. PMID 23115221 DOI: 10.1124/jpet.112.198796  0.48
2013 Freitas K, Negus S, Carroll FI, Damaj MI. In vivo pharmacological interactions between a type II positive allosteric modulator of α7 nicotinic ACh receptors and nicotinic agonists in a murine tonic pain model British Journal of Pharmacology. 169: 567-579. PMID 23004024 DOI: 10.1111/j.1476-5381.2012.02226.x  0.48
2013 Muldoon PP, Lichtman AH, Parsons LH, Damaj MI. The role of fatty acid amide hydrolase inhibition in nicotine reward and dependence. Life Sciences. 92: 458-62. PMID 22705310 DOI: 10.1016/j.lfs.2012.05.015  0.48
2013 Jackson KJ, McLaughlin JP, Carroll FI, Damaj MI. Effects of the kappa opioid receptor antagonist, norbinaltorphimine, on stress and drug-induced reinstatement of nicotine-conditioned place preference in mice. Psychopharmacology. 226: 763-8. PMID 22526543 DOI: 10.1007/s00213-012-2716-y  0.48
2012 Jackson KJ, Sanjakdar SS, Chen X, Damaj MI. Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice. Plos One. 7: e51154. PMID 23226481 DOI: 10.1371/journal.pone.0051154  0.48
2012 Jackson KJ, Wang JB, Barbier E, Chen X, Damaj MI. Acute behavioral effects of nicotine in male and female HINT1 knockout mice. Genes, Brain, and Behavior. 11: 993-1000. PMID 22827509 DOI: 10.1111/j.1601-183X.2012.00827.x  0.48
2012 Ondachi P, Castro A, Luetje CW, Damaj MI, Mascarella SW, Navarro HA, Carroll FI. Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine. Journal of Medicinal Chemistry. 55: 6512-22. PMID 22742586 DOI: 10.1021/jm300575y  0.48
2012 AlSharari SD, Carroll FI, McIntosh JM, Damaj MI. The antinociceptive effects of nicotinic partial agonists varenicline and sazetidine-A in murine acute and tonic pain models. The Journal of Pharmacology and Experimental Therapeutics. 342: 742-9. PMID 22678099 DOI: 10.1124/jpet.112.194506  0.48
2012 George AA, Lucero LM, Damaj MI, Lukas RJ, Chen X, Whiteaker P. Function of human α3β4α5 nicotinic acetylcholine receptors is reduced by the α5(D398N) variant. The Journal of Biological Chemistry. 287: 25151-62. PMID 22665477 DOI: 10.1074/jbc.M112.379339  0.48
2012 Grabus SD, Carroll FI, Damaj MI. Bupropion and its main metabolite reverse nicotine chronic tolerance in the mouse. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 14: 1356-61. PMID 22589419 DOI: 10.1093/ntr/nts088  0.48
2012 Tobey KM, Walentiny DM, Wiley JL, Carroll FI, Damaj MI, Azar MR, Koob GF, George O, Harris LS, Vann RE. Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice. Psychopharmacology. 223: 159-68. PMID 22526534 DOI: 10.1007/s00213-012-2703-3  0.48
2011 Jackson KJ, Chen X, Miles MF, Harenza J, Damaj MI. The neuropeptide galanin and variants in the GalR1 gene are associated with nicotine dependence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2339-48. PMID 21796100 DOI: 10.1038/npp.2011.123  0.48
2011 Kota D, Sanjakdar S, Marks MJ, Khabour O, Alzoubi K, Damaj MI. Exploring behavioral and molecular mechanisms of nicotine reward in adolescent mice Biochemical Pharmacology. 82: 1008-1014. PMID 21708139 DOI: 10.1016/j.bcp.2011.06.019  0.48
2011 Carroll FI, Muresan AZ, Blough BE, Navarro HA, Mascarella SW, Eaton JB, Huang X, Damaj MI, Lukas RJ. Synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues and their effects on monoamine uptake, nicotinic acetylcholine receptor function, and behavioral effects of nicotine. Journal of Medicinal Chemistry. 54: 1441-8. PMID 21319801 DOI: 10.1021/jm1014555  0.48
2011 George O, Lloyd A, Carroll FI, Damaj MI, Koob GF. Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration. Psychopharmacology. 213: 715-22. PMID 20924754 DOI: 10.1007/s00213-010-2024-3  0.48
2010 Carroll FI, Blough BE, Mascarella SW, Navarro HA, Eaton JB, Lukas RJ, Damaj MI. Nicotinic acetylcholine receptor efficacy and pharmacological properties of 3-(substituted phenyl)-2β-substituted tropanes. Journal of Medicinal Chemistry. 53: 8345-53. PMID 21058665 DOI: 10.1021/jm100994w  0.48
2010 Zhang Y, Gilliam A, Maitra R, Damaj MI, Tajuba JM, Seltzman HH, Thomas BF. Synthesis and biological evaluation of bivalent ligands for the cannabinoid 1 receptor. Journal of Medicinal Chemistry. 53: 7048-60. PMID 20845959 DOI: 10.1021/jm1006676  0.48
2010 Abdrakhmanova GR, Blough BE, Nesloney C, Navarro HA, Damaj MI, Carroll FI. In vitro and in vivo characterization of a novel negative allosteric modulator of neuronal nAChRs. Neuropharmacology. 59: 511-7. PMID 20633568 DOI: 10.1016/j.neuropharm.2010.07.006  0.36
2010 Abdrakhmanova GR, AlSharari S, Kang M, Damaj MI, Akbarali HI. {alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G761-8. PMID 20595621 DOI: 10.1152/ajpgi.00175.2010  0.48
2010 Damaj MI, Grabus SD, Navarro HA, Vann RE, Warner JA, King LS, Wiley JL, Blough BE, Lukas RJ, Carroll FI. Effects of hydroxymetabolites of bupropion on nicotine dependence behavior in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 1087-95. PMID 20576796 DOI: 10.1124/jpet.110.166850  0.48
2010 Lukas RJ, Muresan AZ, Damaj MI, Blough BE, Huang X, Navarro HA, Mascarella SW, Eaton JB, Marxer-Miller SK, Carroll FI. Synthesis and characterization of in vitro and in vivo profiles of hydroxybupropion analogues: aids to smoking cessation. Journal of Medicinal Chemistry. 53: 4731-48. PMID 20509659 DOI: 10.1021/jm1003232  0.48
2010 Jackson KJ, Marks MJ, Vann RE, Chen X, Gamage TF, Warner JA, Damaj MI. Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 137-46. PMID 20400469 DOI: 10.1124/jpet.110.165738  0.48
2010 Jackson KJ, Carroll FI, Negus SS, Damaj MI. Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse. Psychopharmacology. 210: 285-94. PMID 20232057 DOI: 10.1007/s00213-010-1803-1  0.48
2010 Carroll FI, Blough BE, Mascarella SW, Navarro HA, Eaton JB, Lukas RJ, Damaj MI. Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for smoking cessation. Journal of Medicinal Chemistry. 53: 2204-14. PMID 20158204 DOI: 10.1021/jm9017465  0.48
2009 Jackson KJ, McIntosh JM, Brunzell DH, Sanjakdar SS, Damaj MI. The role of alpha6-containing nicotinic acetylcholine receptors in nicotine reward and withdrawal. The Journal of Pharmacology and Experimental Therapeutics. 331: 547-54. PMID 19644040 DOI: 10.1124/jpet.109.155457  0.48
2009 Jackson KJ, Walters CL, Miles MF, Martin BR, Damaj MI. Characterization of pharmacological and behavioral differences to nicotine in C57Bl/6 and DBA/2 mice. Neuropharmacology. 57: 347-55. PMID 19619563 DOI: 10.1016/j.neuropharm.2009.07.020  0.48
2009 Jackson KJ, Walters CL, Damaj MI. Beta 2 subunit-containing nicotinic receptors mediate acute nicotine-induced activation of calcium/calmodulin-dependent protein kinase II-dependent pathways in vivo. The Journal of Pharmacology and Experimental Therapeutics. 330: 541-9. PMID 19435931 DOI: 10.1124/jpet.109.153171  0.48
2009 Jackson KJ, Kota DH, Martin BR, Damaj MI. The role of various nicotinic receptor subunits and factors influencing nicotine conditioned place aversion. Neuropharmacology. 56: 970-4. PMID 19371584 DOI: 10.1016/j.neuropharm.2009.01.023  0.48
2009 Jackson KJ, Damaj MI. L-type calcium channels and calcium/calmodulin-dependent kinase II differentially mediate behaviors associated with nicotine withdrawal in mice. The Journal of Pharmacology and Experimental Therapeutics. 330: 152-61. PMID 19336664 DOI: 10.1124/jpet.109.151530  0.48
2008 Abdrakhmanova GR, Carroll FI, Damaj MI, Martin BR. 3'-Fluoro substitution in the pyridine ring of epibatidine improves selectivity and efficacy for alpha4beta2 versus alpha3beta4 nAChRs. Neuropharmacology. 55: 1287-92. PMID 18775444 DOI: 10.1016/j.neuropharm.2008.08.007  0.48
2008 Merritt LL, Martin BR, Walters C, Lichtman AH, Damaj MI. The endogenous cannabinoid system modulates nicotine reward and dependence. The Journal of Pharmacology and Experimental Therapeutics. 326: 483-92. PMID 18451315 DOI: 10.1124/jpet.108.138321  0.48
2008 Kota D, Martin BR, Damaj MI. Age-dependent differences in nicotine reward and withdrawal in female mice. Psychopharmacology. 198: 201-10. PMID 18338157 DOI: 10.1007/s00213-008-1117-8  0.48
2008 Jackson KJ, Martin BR, Changeux JP, Damaj MI. Differential role of nicotinic acetylcholine receptor subunits in physical and affective nicotine withdrawal signs. The Journal of Pharmacology and Experimental Therapeutics. 325: 302-12. PMID 18184829 DOI: 10.1124/jpet.107.132977  0.48
2008 Ivy Carroll F, Yokota Y, Ma W, Lee JR, Brieaddy LE, Burgess JP, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3'-(substituted phenyl)deschloroepibatidine analogs. Bioorganic & Medicinal Chemistry. 16: 746-54. PMID 17964169 DOI: 10.1016/j.bmc.2007.10.027  0.48
2007 Carroll FI, Robinson TP, Brieaddy LE, Atkinson RN, Mascarella SW, Damaj MI, Martin BR, Navarro HA. Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. Journal of Medicinal Chemistry. 50: 6383-91. PMID 17994682 DOI: 10.1021/jm0704696  0.48
2007 Hansen HH, Timmermann DB, Peters D, Walters C, Damaj MI, Mikkelsen JD. Alpha-7 nicotinic acetylcholine receptor agonists selectively activate limbic regions of the rat forebrain: An effect similar to antipsychotics Journal of Neuroscience Research. 85: 1810-1818. PMID 17455307 DOI: 10.1002/jnr.21293  0.48
2007 Kota D, Martin BR, Robinson SE, Damaj MI. Nicotine dependence and reward differ between adolescent and adult male mice. The Journal of Pharmacology and Experimental Therapeutics. 322: 399-407. PMID 17446302 DOI: 10.1124/jpet.107.121616  0.48
2007 Damaj MI, Fonck C, Marks MJ, Deshpande P, Labarca C, Lester HA, Collins AC, Martin BR. Genetic approaches identify differential roles for alpha4beta2* nicotinic receptors in acute models of antinociception in mice. The Journal of Pharmacology and Experimental Therapeutics. 321: 1161-9. PMID 17371806 DOI: 10.1124/jpet.106.112649  0.48
2007 Ivy Carroll F, Ma W, Navarro HA, Abraham P, Wolckenhauer SA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs. Bioorganic & Medicinal Chemistry. 15: 678-85. PMID 17098430 DOI: 10.1016/j.bmc.2006.10.061  0.48
2007 Damaj MI, Siu EC, Sellers EM, Tyndale RF, Martin BR. Inhibition of nicotine metabolism by methoxysalen: Pharmacokinetic and pharmacological studies in mice. The Journal of Pharmacology and Experimental Therapeutics. 320: 250-7. PMID 17021260 DOI: 10.1124/jpet.106.111237  0.48
2007 Matta SG, Balfour DJ, Benowitz NL, Boyd RT, Buccafusco JJ, Caggiula AR, Craig CR, Collins AC, Damaj MI, Donny EC, Gardiner PS, Grady SR, Heberlein U, Leonard SS, Levin ED, et al. Guidelines on nicotine dose selection for in vivo research. Psychopharmacology. 190: 269-319. PMID 16896961 DOI: 10.1007/s00213-006-0441-0  0.48
2006 Wright MJ, Vann RE, Gamage TF, Damaj MI, Wiley JL. Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats. Pharmacology, Biochemistry, and Behavior. 85: 507-13. PMID 17112574 DOI: 10.1016/j.pbb.2006.09.020  0.48
2006 Carroll FI, Hu X, Navarro HA, Deschamps J, Abdrakhmanova GR, Damaj MI, Martin BR. Synthesis and pharmacological characterization of nicotinic acetylcholine receptor properties of (+)- and (-)-pyrido-[3,4-b]homotropanes. Journal of Medicinal Chemistry. 49: 3244-50. PMID 16722642 DOI: 10.1021/jm060122n  0.48
2006 Abdrakhmanova GR, Damaj MI, Carroll FI, Martin BR. 2-Fluoro-3-(4-nitro-phenyl)deschloroepibatidine is a novel potent competitive antagonist of human neuronal alpha4beta2 nAChRs. Molecular Pharmacology. 69: 1945-52. PMID 16505153 DOI: 10.1124/mol.105.021782  0.48
2006 Grabus SD, Martin BR, Brown SE, Damaj MI. Nicotine place preference in the mouse: influences of prior handling, dose and strain and attenuation by nicotinic receptor antagonists. Psychopharmacology. 184: 456-63. PMID 16463055 DOI: 10.1007/s00213-006-0305-7  0.48
2006 Walters CL, Brown S, Changeux JP, Martin B, Damaj MI. The beta2 but not alpha7 subunit of the nicotinic acetylcholine receptor is required for nicotine-conditioned place preference in mice. Psychopharmacology. 184: 339-44. PMID 16416156 DOI: 10.1007/s00213-005-0295-x  0.48
2005 Carroll FI, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis and pharmacological characterization of exo-2-(2'-chloro-5-pyridinyl)-7-(endo and exo)-aminobicyclo[2.2.1]heptanes as novel epibatidine analogues. Journal of Medicinal Chemistry. 48: 7491-5. PMID 16279810 DOI: 10.1021/jm058243v  0.48
2005 Damaj MI, Wiley JL, Martin BR, Papke RL. In vivo characterization of a novel inhibitor of CNS nicotinic receptors. European Journal of Pharmacology. 521: 43-8. PMID 16181622 DOI: 10.1016/j.ejphar.2005.06.056  0.48
2005 Dukat M, Ramunno A, Banzi R, Damaj MI, Martin B, Glennon RA. 3-(2-Aminoethyl)pyridine analogs as α4β2 nicotinic cholinergic receptor ligands Bioorganic and Medicinal Chemistry Letters. 15: 4308-4312. PMID 16039854 DOI: 10.1016/j.bmcl.2005.06.053  0.48
2005 Ramunno A, Dukat M, Lee M, Young R, El-Zahabi M, Damaj MI, Martin B, Glennon RA. 6-(2-Phenylethyl)nicotine: A novel nicotinic cholinergic receptor ligand Bioorganic and Medicinal Chemistry Letters. 15: 3237-3240. PMID 15925512 DOI: 10.1016/j.bmcl.2005.04.072  0.48
2005 Carroll FI, Ma W, Yokota Y, Lee JR, Brieaddy LE, Navarro HA, Damaj MI, Martin BR. Synthesis, nicotinic acetylcholine receptor binding, and antinociceptive properties of 3'-substituted deschloroepibatidine analogues. Novel nicotinic antagonists. Journal of Medicinal Chemistry. 48: 1221-8. PMID 15715488 DOI: 10.1021/jm040160b  0.48
2005 Grabus SD, Martin BR, Batman AM, Tyndale RF, Sellers E, Damaj MI. Nicotine physical dependence and tolerance in the mouse following chronic oral administration. Psychopharmacology. 178: 183-92. PMID 15365686 DOI: 10.1007/s00213-004-2007-3  0.48
2004 Damaj MI, Hunter RG, Martin BR, Kuhar MJ. Intrathecal CART (55-102) enhances the spinal analgesic actions of morphine in mice. Brain Research. 1024: 146-9. PMID 15451376 DOI: 10.1016/j.brainres.2004.07.058  0.48
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