Larry W. Robertson - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Toxicology, Public Health

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Ronis MJ, Watt J, Pulliam CF, Williams AE, Alund AW, Haque E, Gadupudi GS, Robertson LW. Skeletal toxicity resulting from exposure of growing male rats to coplanar PCB 126 is associated with disruption of calcium homeostasis and the GH-IGF-1 axis and direct effects on bone formation. Archives of Toxicology. PMID 31820026 DOI: 10.1007/s00204-019-02645-w  0.88
2019 Gourronc FA, Perdew GH, Robertson LW, Klingelhutz AJ. PCB126 blocks the thermogenic beiging response of adipocytes. Environmental Science and Pollution Research International. PMID 31721030 DOI: 10.1007/s11356-019-06663-0  0.88
2018 Rodriguez EA, Vanle BC, Doorn JA, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly observed airborne polychlorinated biphenyls display selective uptake and toxicity in N27, SH-SY5Y, and HepG2 cells. Environmental Toxicology and Pharmacology. 62: 69-78. PMID 29986280 DOI: 10.1016/j.etap.2018.06.010  0.76
2018 Gadupudi GS, Elser BA, Sandgruber FA, Li X, Gibson-Corley KN, Robertson LW. PCB126 inhibits the activation of AMPK-CREB signal transduction required for energy sensing in liver. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29474705 DOI: 10.1093/toxsci/kfy041  0.88
2018 Parker VS, Squirewell EJ, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated and sulfated metabolites of commonly occurring airborne polychlorinated biphenyls inhibit human steroid sulfotransferases SULT1E1 and SULT2A1. Environmental Toxicology and Pharmacology. 58: 196-201. PMID 29408762 DOI: 10.1016/j.etap.2018.01.010  0.76
2018 Li X, Holland EB, Feng W, Zheng J, Dong Y, Pessah IN, Duffel MW, Robertson LW, Lehmler HJ. Authentication of synthetic environmental contaminants and their (bio)transformation products in toxicology: polychlorinated biphenyls as an example. Environmental Science and Pollution Research International. PMID 29322390 DOI: 10.1007/s11356-017-1162-0  0.76
2017 Klaren WD, Vine D, Vogt S, Robertson LW. Spatial distribution of metals within the liver acinus and their perturbation by PCB126. Environmental Science and Pollution Research International. PMID 28940161 DOI: 10.1007/s11356-017-0202-0  0.52
2017 Dhakal K, Gadupudi GS, Lehmler HJ, Ludewig G, Duffel MW, Robertson LW. Sources and toxicities of phenolic polychlorinated biphenyls (OH-PCBs). Environmental Science and Pollution Research International. PMID 28744683 DOI: 10.1007/s11356-017-9694-x  0.88
2017 Gourronc FA, Robertson LW, Klingelhutz AJ. A delayed proinflammatory response of human preadipocytes to PCB126 is dependent on the aryl hydrocarbon receptor. Environmental Science and Pollution Research International. PMID 28699004 DOI: 10.1007/s11356-017-9676-z  0.88
2016 Grimm FA, Lehmler HJ, Koh WX, DeWall J, Teesch LM, Hornbuckle KC, Thorne PS, Robertson LW, Duffel MW. Identification of a sulfate metabolite of PCB 11 in human serum. Environment International. PMID 27816204 DOI: 10.1016/j.envint.2016.10.023  0.76
2016 Gadupudi GS, Klingelhutz AJ, Robertson LW. Diminished phosphorylation of CREB is a key event in the dysregulation of gluconeogenesis and glycogenolysis in PCB126 hepatotoxicity. Chemical Research in Toxicology. PMID 27509375 DOI: 10.1021/acs.chemrestox.6b00172  0.88
2016 Wu X, Yang J, Morisseau C, Robertson LW, Hammock B, Lehmler HJ. 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) decreases hepatic and systemic ratios of epoxide to diol metabolites of unsaturated fatty acids in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27208083 DOI: 10.1093/toxsci/kfw084  0.76
2016 Rodriguez EA, Li X, Lehmler HJ, Robertson LW, Duffel MW. Sulfation of lower chlorinated polychlorinated biphenyls increases their affinity for the major drug-binding sites of human serum albumin. Environmental Science & Technology. PMID 27116425 DOI: 10.1021/acs.est.6b00484  0.72
2015 Wang B, Klaren WD, Wels BR, Simmons DL, Olivier AK, Wang K, Robertson LW, Ludewig G. Dietary manganese modulates PCB126 toxicity, metal status and MnSOD in the rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26660635 DOI: 10.1093/toxsci/kfv312  0.4
2015 Gadupudi GS, Klaren WD, Olivier AK, Klingelhutz AJ, Robertson LW. PCB126-induced disruption in gluconeogenesis and fatty acid oxidation precedes fatty liver in male rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26396156 DOI: 10.1093/toxsci/kfv215  0.88
2015 Wangpradit O, Rahaman A, Mariappan SV, Buettner GR, Robertson LW, Luthe G. Breaking the dogma: PCB-derived semiquinone free radicals do not form covalent adducts with DNA, GSH, and amino acids. Environmental Science and Pollution Research International. PMID 26396011 DOI: 10.1007/s11356-015-5007-4  0.4
2015 Li M, Teesch LM, Murry DJ, Pope RM, Li Y, Robertson LW, Ludewig G. Cytochrome c adducts with PCB quinoid metabolites. Environmental Science and Pollution Research International. PMID 26062463 DOI: 10.1007/s11356-015-4801-3  0.4
2015 Grimm FA, He X, Teesch LM, Lehmler HJ, Robertson LW, Duffel MW. Tissue Distribution, Metabolism, and Excretion of 3,3'-Dichloro-4'-sulfooxy-biphenyl in the Rat. Environmental Science & Technology. 49: 8087-95. PMID 26046945 DOI: 10.1021/acs.est.5b01499  0.4
2015 Shen H, Robertson LW, Ludewig G. Regulatory effects of dioxin-like and non-dioxin-like PCBs and other AhR ligands on the antioxidant enzymes paraoxonase 1/2/3. Environmental Science and Pollution Research International. PMID 26006071 DOI: 10.1007/s11356-015-4722-1  0.4
2015 Grimm FA, Hu D, Kania-Korwel I, Lehmler HJ, Ludewig G, Hornbuckle KC, Duffel MW, Bergman Å, Robertson LW. Metabolism and metabolites of polychlorinated biphenyls. Critical Reviews in Toxicology. 45: 245-72. PMID 25629923 DOI: 10.3109/10408444.2014.999365  0.72
2015 Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Modulating inhibitors of transthyretin fibrillogenesis via sulfation: polychlorinated biphenyl sulfates as models. Chemico-Biological Interactions. 228: 1-8. PMID 25595224 DOI: 10.1016/j.cbi.2015.01.002  0.4
2015 Gadupudi G, Gourronc FA, Ludewig G, Robertson LW, Klingelhutz AJ. PCB126 inhibits adipogenesis of human preadipocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 132-41. PMID 25304490 DOI: 10.1016/j.tiv.2014.09.015  0.88
2014 Aqil F, Shen H, Jeyabalan J, Xin X, Lehmler HJ, Ludewig G, Robertson LW, Gupta RC. Sustained expression of CYPs and DNA adduct accumulation with continuous exposure to PCB126 and PCB153 through a new delivery method: Polymeric implants. Toxicology Reports. 1: 820-833. PMID 25530946 DOI: 10.1016/j.toxrep.2014.09.010  0.76
2014 Dhakal K, Uwimana E, Adamcakova-Dodd A, Thorne PS, Lehmler HJ, Robertson LW. Disposition of phenolic and sulfated metabolites after inhalation exposure to 4-chlorobiphenyl (PCB3) in female rats. Chemical Research in Toxicology. 27: 1411-20. PMID 24988477 DOI: 10.1021/tx500150h  0.76
2014 Vorrink SU, Sarsour EH, Olivier AK, Robertson LW, Goswami PC, Domann FE. PCB 126 perturbs hypoxia-induced HIF-1α activity and glucose consumption in human HepG2 cells. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft FüR Toxikologische Pathologie. 66: 377-82. PMID 24916446 DOI: 10.1016/j.etp.2014.05.005  0.52
2014 Narbonne JF, Robertson LW. 7th International PCB Workshop: Chemical mixtures in a complex world Environmental Science and Pollution Research. 21: 6269-6275. PMID 24627200 DOI: 10.1007/s11356-014-2706-1  0.72
2014 Ekuase EJ, Lehmler HJ, Robertson LW, Duffel MW. Binding interactions of hydroxylated polychlorinated biphenyls (OHPCBs) with human hydroxysteroid sulfotransferase hSULT2A1. Chemico-Biological Interactions. 212: 56-64. PMID 24508592 DOI: 10.1016/j.cbi.2014.01.018  0.72
2014 Kim JS, Klösener J, Flor S, Peters TM, Ludewig G, Thorne PS, Robertson LW, Luthe G. Toxicity assessment of air-delivered particle-bound polybrominated diphenyl ethers. Toxicology. 317: 31-9. PMID 24451063 DOI: 10.1016/j.tox.2014.01.005  0.76
2014 Shen H, Li M, Wang B, Lai IK, Robertson LW, Ludewig G. Dietary antioxidants (selenium and N-acetylcysteine) modulate paraoxonase 1 (PON1) in PCB 126-exposed rats. Environmental Science and Pollution Research International. 21: 6384-99. PMID 23644946 DOI: 10.1007/s11356-013-1690-1  0.76
2014 Salman KN, Stuart MA, Schmidt J, Borges T, McClain CJ, Robinson FR, Li M, Robertson LW. The effects of 3,3',4,4'-tetrabromobiphenyl on rats fed diets containing a constant level of copper and varying levels of molybdenum. Environmental Science and Pollution Research International. 21: 6400-9. PMID 23532536 DOI: 10.1007/s11356-013-1638-5  0.72
2013 Qin X, Lehmler HJ, Teesch LM, Robertson LW, Duffel MW. Chlorinated biphenyl quinones and phenyl-2,5-benzoquinone differentially modify the catalytic activity of human hydroxysteroid sulfotransferase hSULT2A1. Chemical Research in Toxicology. 26: 1474-85. PMID 24059442 DOI: 10.1021/tx400207q  0.72
2013 Zhu Y, Mapuskar KA, Marek RF, Xu W, Lehmler HJ, Robertson LW, Hornbuckle KC, Spitz DR, Aykin-Burns N. A new player in environmentally induced oxidative stress: polychlorinated biphenyl congener, 3,3'-dichlorobiphenyl (PCB11). Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 39-50. PMID 23997111 DOI: 10.1093/toxsci/kft186  0.72
2013 Svensson RU, Bannick NL, Marin MJ, Robertson LW, Lynch CF, Henry MD. Chronic chlorpyrifos exposure does not promote prostate cancer in prostate specific PTEN mutant mice. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 32: 29-39. PMID 23758150 DOI: 10.1615/JEnvironPatholToxicolOncol.2013006778  0.72
2013 Dhakal K, Adamcakova-Dodd A, Lehmler HJ, Thorne PS, Robertson LW. Sulfate conjugates are urinary markers of inhalation exposure to 4-chlorobiphenyl (PCB3). Chemical Research in Toxicology. 26: 853-5. PMID 23713983 DOI: 10.1021/tx4001539  0.76
2013 Grimm FA, Lehmler HJ, He X, Robertson LW, Duffel MW. Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin. Environmental Health Perspectives. 121: 657-62. PMID 23584369 DOI: 10.1289/ehp.1206198  0.72
2013 Lai IK, Klaren WD, Li M, Wels B, Simmons DL, Olivier AK, Haschek WM, Wang K, Ludewig G, Robertson LW. Does dietary copper supplementation enhance or diminish PCB126 toxicity in the rodent liver? Chemical Research in Toxicology. 26: 634-44. PMID 23527585 DOI: 10.1021/tx400049s  0.72
2013 Rignall B, Grote K, Gavrilov A, Weimer M, Kopp-Schneider A, Krause E, Appel KE, Buchmann A, Robertson LW, Lehmler HJ, Kania-Korwel I, Chahoud I, Schwarz M. Biological and tumor-promoting effects of dioxin-like and non-dioxin-like polychlorinated biphenyls in mouse liver after single or combined treatment. Toxicological Sciences : An Official Journal of the Society of Toxicology. 133: 29-41. PMID 23457121 DOI: 10.1093/toxsci/kft034  0.72
2013 Ludewig G, Robertson LW. Polychlorinated biphenyls (PCBs) as initiating agents in hepatocellular carcinoma. Cancer Letters. 334: 46-55. PMID 23211541 DOI: 10.1016/j.canlet.2012.11.041  0.76
2012 Dhakal K, He X, Lehmler HJ, Teesch LM, Duffel MW, Robertson LW. Identification of sulfated metabolites of 4-chlorobiphenyl (PCB3) in the serum and urine of male rats. Chemical Research in Toxicology. 25: 2796-804. PMID 23137097 DOI: 10.1021/tx300416v  0.72
2012 Lai IK, Dhakal K, Gadupudi GS, Li M, Ludewig G, Robertson LW, Olivier AK. N-acetylcysteine (NAC) diminishes the severity of PCB 126-induced fatty liver in male rodents. Toxicology. 302: 25-33. PMID 22824115 DOI: 10.1016/j.tox.2012.07.007  0.88
2012 Shen H, Robertson LW, Ludewig G. Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats. Toxicology Letters. 209: 291-8. PMID 22266287 DOI: 10.1016/j.toxlet.2012.01.003  0.76
2011 Bunaciu RP, Tharappel JC, Lehmler HJ, Lee EY, Robertson LW, Bruckner GG, Spear BT, Glauert HP. Role of oil vehicle on hepatic cell proliferation in PCB-treated rats. Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society For Environmental Toxicology and Cancer. 30: 273-82. PMID 22181977  0.76
2011 Wang B, Robertson LW, Wang K, Ludewig G. Species difference in the regulation of cytochrome P450 2S1: lack of induction in rats by the aryl hydrocarbon receptor agonist PCB126. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 41: 1031-43. PMID 21970748 DOI: 10.3109/00498254.2011.603763  0.76
2011 Ekuase EJ, Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as inhibitors of the sulfation of dehydroepiandrosterone catalyzed by human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 24: 1720-8. PMID 21913674 DOI: 10.1021/tx200260h  0.72
2011 Lai IK, Chai Y, Simmons D, Watson WH, Tan R, Haschek WM, Wang K, Wang B, Ludewig G, Robertson LW. Dietary selenium as a modulator of PCB 126-induced hepatotoxicity in male Sprague-Dawley rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 202-14. PMID 21865291 DOI: 10.1093/toxsci/kfr215  0.76
2011 Song Y, Ambati J, Parkin S, Rankin SE, Robertson LW, Lehmler HJ. Crystal structure and density functional theory studies of toxic quinone metabolites of polychlorinated biphenyls. Chemosphere. 85: 386-92. PMID 21824639 DOI: 10.1016/j.chemosphere.2011.07.004  0.72
2011 Robertson LW, Ludewig G. Polychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs. Gefahrstoffe, Reinhaltung Der Luft = Air Quality Control / Herausgeber, Bia Und Krdl Im Vdi Und Din. 71: 25-32. PMID 21686028  0.76
2011 Liu Y, Lehmler HJ, Robertson LW, Duffel MW. Physicochemical properties of hydroxylated polychlorinated biphenyls aid in predicting their interactions with rat sulfotransferase 1A1 (rSULT1A1). Chemico-Biological Interactions. 189: 153-60. PMID 21130751 DOI: 10.1016/j.cbi.2010.11.009  0.72
2010 Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. 4'-Chloro-biphenyl-3-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o2306. PMID 21588655 DOI: 10.1107/S1600536810031338  0.72
2010 Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. 3',4'-Dichloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o1615-6. PMID 21587847 DOI: 10.1107/S1600536810020362  0.72
2010 Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. Biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 66: o1073. PMID 21579128 DOI: 10.1107/S1600536810012845  0.72
2010 Wangpradit O, Moman E, Nolan KB, Buettner GR, Robertson LW, Luthe G. Observation of an unusual electronically distorted semiquinone radical of PCB metabolites in the active site of prostaglandin H synthase-2. Chemosphere. 81: 1501-8. PMID 20843536 DOI: 10.1016/j.chemosphere.2010.08.041  0.72
2010 Ludewig G, Robertson LW. A primary objective of the 2008 workshop was to bring these scientists together in one location to facilitate interactions and the exchange of information. Preface. Environment International. 36: 813. PMID 20688397 DOI: 10.1016/j.envint.2010.07.004  0.76
2010 Ward EM, Schulte PA, Straif K, Hopf NB, Caldwell JC, Carreón T, DeMarini DM, Fowler BA, Goldstein BD, Hemminki K, Hines CJ, Pursiainen KH, Kuempel E, Lewtas J, Lunn RM, ... ... Robertson LW, et al. Research recommendations for selected IARC-classified agents. Environmental Health Perspectives. 118: 1355-62. PMID 20562050 DOI: 10.1289/ehp.0901828  0.72
2010 Xie W, Wang K, Robertson LW, Ludewig G. Investigation of mechanism(s) of DNA damage induced by 4-monochlorobiphenyl (PCB3) metabolites. Environment International. 36: 950-61. PMID 20129669 DOI: 10.1016/j.envint.2009.12.004  0.76
2010 Lai I, Chai Y, Simmons D, Luthe G, Coleman MC, Spitz D, Haschek WM, Ludewig G, Robertson LW. Acute toxicity of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) in male Sprague-Dawley rats: effects on hepatic oxidative stress, glutathione and metals status. Environment International. 36: 918-23. PMID 19969354 DOI: 10.1016/j.envint.2009.11.002  0.72
2010 Ravoori S, Srinivasan C, Pereg D, Robertson LW, Ayotte P, Gupta RC. Protective effects of selenium against DNA adduct formation in Inuit environmentally exposed to PCBs. Environment International. 36: 980-6. PMID 19735942 DOI: 10.1016/j.envint.2009.08.001  0.72
2010 Li X, Parkin S, Duffel MW, Robertson LW, Lehmler HJ. An efficient approach to sulfate metabolites of polychlorinated biphenyls. Environment International. 36: 843-8. PMID 19345419 DOI: 10.1016/j.envint.2009.02.005  0.72
2010 Telu S, Parkin S, Robertson LW, Lehmler HJ. Improved syntheses of non-dioxin-like polychlorinated biphenyls (PCBs) and some of their sulfur-containing metabolites. Environment International. 36: 828-34. PMID 19261331 DOI: 10.1016/j.envint.2009.01.013  0.76
2009 Zhu Y, Kalen AL, Li L, Lehmler HJ, Robertson LW, Goswami PC, Spitz DR, Aykin-Burns N. Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radical Biology & Medicine. 47: 1762-71. PMID 19796678 DOI: 10.1016/j.freeradbiomed.2009.09.024  0.72
2009 Dreiem A, Rykken S, Lehmler HJ, Robertson LW, Fonnum F. Hydroxylated polychlorinated biphenyls increase reactive oxygen species formation and induce cell death in cultured cerebellar granule cells. Toxicology and Applied Pharmacology. 240: 306-13. PMID 19631230 DOI: 10.1016/j.taap.2009.07.016  0.72
2009 Suh YW, Buettner GR, Venkataraman S, Treimer SE, Robertson LW, Ludewig G. UVA/B-induced formation of free radicals from decabromodiphenyl ether. Environmental Science & Technology. 43: 2581-8. PMID 19452920 DOI: 10.1021/es8022978  0.72
2009 Li X, Robertson LW, Lehmler HJ. Electron ionization mass spectral fragmentation study of sulfation derivatives of polychlorinated biphenyls. Chemistry Central Journal. 3: 5. PMID 19272150 DOI: 10.1186/1752-153X-3-5  0.76
2009 Spencer WA, Lehmler HJ, Robertson LW, Gupta RC. Oxidative DNA adducts after Cu(2+)-mediated activation of dihydroxy PCBs: role of reactive oxygen species. Free Radical Biology & Medicine. 46: 1346-52. PMID 19233261 DOI: 10.1016/j.freeradbiomed.2009.02.005  0.72
2009 Liu Y, Smart JT, Song Y, Lehmler HJ, Robertson LW, Duffel MW. Structure-activity relationships for hydroxylated polychlorinated biphenyls as substrates and inhibitors of rat sulfotransferases and modification of these relationships by changes in thiol status. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1065-72. PMID 19196841 DOI: 10.1124/dmd.108.026021  0.72
2009 Klösener J, Peters TM, Adamcakova-Dodd A, Teesch LM, Thorne PS, Robertson LW, Luthe G. Innovative application of fluoro tagging to trace airborne particulate and gas-phase polybrominated diphenyl ether exposures. Chemical Research in Toxicology. 22: 179-86. PMID 19111055 DOI: 10.1021/tx8003032  0.52
2009 Wangpradit O, Teesch LM, Mariappan SV, Duffel MW, Norstrom K, Robertson LW, Luthe G. Oxidation of 4-chlorobiphenyl metabolites to electrophilic species by prostaglandin H synthase. Chemical Research in Toxicology. 22: 64-71. PMID 19105592 DOI: 10.1021/tx800300t  0.72
2009 Pessah IN, Lehmler HJ, Robertson LW, Perez CF, Cabrales E, Bose DD, Feng W. Enantiomeric specificity of (-)-2,2',3,3',6,6'-hexachlorobiphenyl toward ryanodine receptor types 1 and 2. Chemical Research in Toxicology. 22: 201-7. PMID 18954145 DOI: 10.1021/tx800328u  0.72
2008 Ravoori S, Ayotte P, Srinivasan C, Pereg D, Robertson LW, Russell GK, Jeyabalan J, Gupta RC. DNA damage associated with PCBs in the whole blood cells of Inuit. Environmental Toxicology and Pharmacology. 25: 273-6. PMID 21783863 DOI: 10.1016/j.etap.2007.10.027  0.72
2008 Robertson LW, Sulkowski W, Hennig B. Preface. Environmental Toxicology and Pharmacology. 25: 127. PMID 21783846 DOI: 10.1016/j.etap.2007.10.006  0.6
2008 Li X, Parkin S, Robertson LW, Lehmler HJ. 4'-Chloro-biphenyl-4-yl 2,2,2-trichloro-ethyl sulfate. Acta Crystallographica. Section E, Structure Reports Online. 64: o2464. PMID 21581432 DOI: 10.1107/S1600536808038865  0.76
2008 Telu S, Parkin S, Robertson LW, Lehmler HJ. 1,3,5-Trichloro-2-methoxy-benzene. Acta Crystallographica. Section E, Structure Reports Online. 64: o424. PMID 21201451 DOI: 10.1107/S160053680800055X  0.76
2008 Glauert HP, Tharappel JC, Lu Z, Stemm D, Banerjee S, Chan LS, Lee EY, Lehmler HJ, Robertson LW, Spear BT. Role of oxidative stress in the promoting activities of pcbs. Environmental Toxicology and Pharmacology. 25: 247-50. PMID 19122744 DOI: 10.1016/j.etap.2007.10.025  0.76
2008 Song Y, Buettner GR, Parkin S, Wagner BA, Robertson LW, Lehmler HJ. Chlorination increases the persistence of semiquinone free radicals derived from polychlorinated biphenyl hydroquinones and quinones. The Journal of Organic Chemistry. 73: 8296-304. PMID 18839991 DOI: 10.1021/jo801397g  0.72
2008 Tharappel JC, Lehmler HJ, Srinivasan C, Robertson LW, Spear BT, Glauert HP. Effect of antioxidant phytochemicals on the hepatic tumor promoting activity of 3,3',4,4'-tetrachlorobiphenyl (PCB-77). Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 46: 3467-74. PMID 18796325 DOI: 10.1016/j.fct.2008.08.023  0.72
2008 Venkatesha VA, Venkataraman S, Sarsour EH, Kalen AL, Buettner GR, Robertson LW, Lehmler HJ, Goswami PC. Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radical Biology & Medicine. 45: 1094-102. PMID 18691649 DOI: 10.1016/j.freeradbiomed.2008.07.007  0.72
2008 Glauert HP, Tharappel JC, Banerjee S, Chan NL, Kania-Korwel I, Lehmler HJ, Lee EY, Robertson LW, Spear BT. Inhibition of the promotion of hepatocarcinogenesis by 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) by the deletion of the p50 subunit of NF-kappa B in mice. Toxicology and Applied Pharmacology. 232: 302-8. PMID 18644402 DOI: 10.1016/j.taap.2008.06.013  0.76
2008 Ludewig G, Lehmann L, Esch H, Robertson LW. Metabolic Activation of PCBs to Carcinogens in Vivo - A Review. Environmental Toxicology and Pharmacology. 25: 241-6. PMID 18452002 DOI: 10.1016/j.etap.2007.10.029  0.76
2008 Kania-Korwel I, Xie W, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl (PCB 136) in mice after induction of CYP enzymes. Archives of Environmental Contamination and Toxicology. 55: 510-7. PMID 18437444 DOI: 10.1007/s00244-007-9111-4  0.76
2008 Luthe G, Garcia Boy R, Jacobus J, Smith BJ, Rahaman A, Robertson LW, Ludewig G. Xenobiotic geometry and media pH determine cytotoxicity through solubility. Chemical Research in Toxicology. 21: 1017-27. PMID 18402468 DOI: 10.1021/tx700214p  0.72
2008 Kania-Korwel I, Hornbuckle KC, Robertson LW, Lehmler HJ. Dose-dependent enantiomeric enrichment of 2,2',3,3',6,6'-hexachlorobiphenyl in female mice. Environmental Toxicology and Chemistry / Setac. 27: 299-305. PMID 18348647 DOI: 10.1897/07-359R.1  0.76
2008 Stemm DN, Tharappel JC, Lehmler HJ, Srinivasan C, Morris JS, Spate VL, Robertson LW, Spear BT, Glauert HP. Effect of dietary selenium on the promotion of hepatocarcinogenesis by 3,3', 4,4'-tetrachlorobiphenyl and 2,2', 4,4', 5,5'-hexachlorobiphenyl. Experimental Biology and Medicine (Maywood, N.J.). 233: 366-76. PMID 18296742 DOI: 10.3181/0708-RM-211  0.72
2008 Sacco JC, Lehmler HJ, Robertson LW, Li W, James MO. Glucuronidation of polychlorinated biphenylols and UDP-glucuronic acid concentrations in channel catfish liver and intestine. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 623-30. PMID 18180271 DOI: 10.1124/dmd.107.019596  0.76
2007 Robertson LW, Berberian I, Borges T, Chen LC, Chow CK, Glauert HP, Filser JG, Thomas H. Suppression of peroxisomal enzyme activities and cytochrome P450 4A isozyme expression by congeneric polybrominated and polychlorinated biphenyls. Ppar Research. 2007: 15481. PMID 18274624 DOI: 10.1155/2007/15481  0.44
2007 Bunaciu RP, Tharappel JC, Lehmler HJ, Kania-Korwel I, Robertson LW, Srinivasan C, Spear BT, Glauert HP. The effect of dietary glycine on the hepatic tumor promoting activity of polychlorinated biphenyls (PCBs) in rats. Toxicology. 239: 147-55. PMID 17703865 DOI: 10.1016/j.tox.2007.06.102  0.72
2007 Zettner MA, Flor S, Ludewig G, Wagner J, Robertson LW, Lehmann L. Quinoid metabolites of 4-monochlorobiphenyl induce gene mutations in cultured Chinese hamster v79 cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 100: 88-98. PMID 17686921 DOI: 10.1093/toxsci/kfm204  0.76
2007 Sadeghi-Aliabadi H, Chan K, Lehmler HJ, Robertson LW, O'Brien PJ. Molecular cytotoxic mechanisms of catecholic polychlorinated biphenyl metabolites in isolated rat hepatocytes. Chemico-Biological Interactions. 167: 184-92. PMID 17408604 DOI: 10.1016/j.cbi.2007.02.011  0.76
2007 Kania-Korwel I, Shaikh NS, Hornbuckle KC, Robertson LW, Lehmler HJ. Enantioselective disposition of PCB 136 (2,2',3,3',6,6'-hexachlorobiphenyl) in C57BL/6 mice after oral and intraperitoneal administration. Chirality. 19: 56-66. PMID 17089340 DOI: 10.1002/chir.20342  0.76
2006 Liu Y, Apak TI, Lehmler HJ, Robertson LW, Duffel MW. Hydroxylated polychlorinated biphenyls are substrates and inhibitors of human hydroxysteroid sulfotransferase SULT2A1. Chemical Research in Toxicology. 19: 1420-5. PMID 17112228 DOI: 10.1021/tx060160+  0.72
2006 Ptak A, Ludewig G, Kapiszewska M, Magnowska Z, Lehmler HJ, Robertson LW, Gregoraszczuk EL. Induction of cytochromes P450, caspase-3 and DNA damage by PCB3 and its hydroxylated metabolites in porcine ovary. Toxicology Letters. 166: 200-11. PMID 16949219 DOI: 10.1016/j.toxlet.2006.07.304  0.76
2006 Bender RP, Lehmler HJ, Robertson LW, Ludewig G, Osheroff N. Polychlorinated biphenyl quinone metabolites poison human topoisomerase IIalpha: altering enzyme function by blocking the N-terminal protein gate. Biochemistry. 45: 10140-52. PMID 16906772 DOI: 10.1021/bi0524666  0.72
2006 Kania-Korwel I, Garrison AW, Avants JK, Hornbuckle KC, Robertson LW, Sulkowski WW, Lehmler HJ. Distribution of chiral PCBs in selected tissues in the laboratory rat. Environmental Science & Technology. 40: 3704-10. PMID 16830530  0.76
2006 Strathmann J, Schwarz M, Tharappel JC, Glauert HP, Spear BT, Robertson LW, Appel KE, Buchmann A. PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 34-40. PMID 16782779 DOI: 10.1093/toxsci/kfl041  0.44
2006 Luthe G, Leonards PE, Reijerink GS, Liu H, Johansen JE, Robertson LW. Monofluorinated analogues of polybrominated diphenyl ethers as analytical standards: synthesis, NMR, and GC-MS characterization and molecular orbital studies. Environmental Science & Technology. 40: 3023-9. PMID 16719106  0.48
2006 Kunz S, Schwarz M, Schilling B, Päpke O, Lehmler HJ, Robertson LW, Schrenk D, Schmitz HJ. Tumor promoting potency of PCBs 28 and 101 in rat liver. Toxicology Letters. 164: 133-43. PMID 16426774 DOI: 10.1016/j.toxlet.2005.12.003  0.76
2006 Wang LQ, Lehmler HJ, Robertson LW, James MO. Polychlorobiphenylols are selective inhibitors of human phenol sulfotransferase 1A1 with 4-nitrophenol as a substrate. Chemico-Biological Interactions. 159: 235-46. PMID 16413005 DOI: 10.1016/j.cbi.2005.12.004  0.76
2005 Kodavanti PRS, Ward TR, Ludewig G, Robertson LW, Birnbaum LS. Polybrominated diphenyl ether (PBDE) effects in rat neuronal cultures: 14C-PBDE accumulation, biological effects, and structure-activity relationships Toxicological Sciences. 88: 181-192. PMID 16107548 DOI: 10.1093/toxsci/kfi289  0.72
2005 Kania-Korwel I, Hornbuckle KC, Peck A, Ludewig G, Robertson LW, Sulkowski WW, Espandiari P, Gairola CG, Lehmler HJ. Congener-specific tissue distribution of aroclor 1254 and a highly chlorinated environmental PCB mixture in rats. Environmental Science & Technology. 39: 3513-20. PMID 15954224  0.76
2005 Wang LQ, Lehmler HJ, Robertson LW, Falany CN, James MO. In vitro inhibition of human hepatic and cDNA-expressed sulfotransferase activity with 3-hydroxybenzo[a]pyrene by polychlorobiphenylols. Environmental Health Perspectives. 113: 680-7. PMID 15929889  0.76
2005 Ptak A, Ludewig G, Lehmler HJ, Wójtowicz AK, Robertson LW, Gregoraszczuk EL. Comparison of the actions of 4-chlorobiphenyl and its hydroxylated metabolites on estradiol secretion by ovarian follicles in primary cells in culture. Reproductive Toxicology (Elmsford, N.Y.). 20: 57-64. PMID 15808786 DOI: 10.1016/j.reprotox.2004.12.003  0.72
2005 Lehmler HJ, Robertson LW, Garrison AW, Kodavanti PR. Effects of PCB 84 enantiomers on [3H]-phorbol ester binding in rat cerebellar granule cells and 45Ca2+-uptake in rat cerebellum. Toxicology Letters. 156: 391-400. PMID 15763638 DOI: 10.1016/j.toxlet.2004.12.011  0.76
2005 Ritchie JM, Vial SL, Fuortes LJ, Robertson LW, Guo H, Reedy VE, Smith EM. Comparison of proposed frameworks for grouping polychlorinated biphenyl congener data applied to a case-control pilot study of prostate cancer. Environmental Research. 98: 104-13. PMID 15721890 DOI: 10.1016/j.envres.2004.05.013  0.72
2005 Glauert HP, Lu Z, Kumar A, Bunaciu RP, Patel S, Tharappel JC, Stemm DN, Lehmler HJ, Lee EY, Robertson LW, Spear BT. Dietary vitamin E does not inhibit the promotion of liver carcinogenesis by polychlorinated biphenyls in rats. The Journal of Nutrition. 135: 283-6. PMID 15671227  0.76
2005 Hennig B, Reiterer G, Toborek M, Matveev SV, Daugherty A, Smart E, Robertson LW. Dietary fat interacts with PCBs to induce changes in lipid metabolism in mice deficient in low-density lipoprotein receptor. Environmental Health Perspectives. 113: 83-7. PMID 15626652  0.6
2005 Espandiari P, Robertson LW, Srinivasan C, Glauert HP. Comparison of different initiation protocols in the resistant hepatocyte model. Toxicology. 206: 373-81. PMID 15588927 DOI: 10.1016/j.tox.2004.07.014  0.44
2004 Kania-Korwel I, Parkin S, Robertson LW, Lehmler HJ. Synthesis of polychlorinated biphenyls and their metabolites with a modified Suzuki-coupling. Chemosphere. 56: 735-44. PMID 15251288 DOI: 10.1016/j.chemosphere.2004.04.035  0.76
2004 Lu Z, Lee EY, Robertson LW, Glauert HP, Spear BT. Effect of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) on hepatocyte proliferation and apoptosis in mice deficient in the p50 subunit of the transcription factor NF-kappaB. Toxicological Sciences : An Official Journal of the Society of Toxicology. 81: 35-42. PMID 15201435 DOI: 10.1093/toxsci/kfh193  0.44
2004 Machala M, Bláha L, Lehmler HJ, Plísková M, Májková Z, Kapplová P, Sovadinová I, Vondrácek J, Malmberg T, Robertson LW. Toxicity of hydroxylated and quinoid PCB metabolites: inhibition of gap junctional intercellular communication and activation of aryl hydrocarbon and estrogen receptors in hepatic and mammary cells. Chemical Research in Toxicology. 17: 340-7. PMID 15025504 DOI: 10.1021/tx030034v  0.76
2004 Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW. Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 41-6. PMID 14976334 DOI: 10.1093/toxsci/kfh097  0.76
2003 Ramadass P, Meerarani P, Toborek M, Robertson LW, Hennig B. Dietary flavonoids modulate PCB-induced oxidative stress, CYP1A1 induction, and AhR-DNA binding activity in vascular endothelial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 212-9. PMID 12970578 DOI: 10.1093/toxsci/kfg227  0.6
2003 Lu Z, Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. Effect of a single dose of polychlorinated biphenyls on hepatic cell proliferation and the DNA binding activity of NF-kappaB and AP-1 in rats. Molecular Carcinogenesis. 37: 171-80. PMID 12891626 DOI: 10.1002/mc.10135  0.44
2003 Choi W, Eum SY, Lee YW, Hennig B, Robertson LW, Toborek M. PCB 104-induced proinflammatory reactions in human vascular endothelial cells: relationship to cancer metastasis and atherogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 75: 47-56. PMID 12805654 DOI: 10.1093/toxsci/kfg149  0.6
2003 Lee YW, Park HJ, Son KW, Hennig B, Robertson LW, Toborek M. 2,2',4,6,6'-pentachlorobiphenyl (PCB 104) induces apoptosis of human microvascular endothelial cells through the caspase-dependent activation of CREB. Toxicology and Applied Pharmacology. 189: 1-10. PMID 12758055  0.6
2003 Tampal NM, Robertson LW, Srinivasan C, Ludewig G. Polychlorinated biphenyls are not substrates for the multidrug resistance transporter-1. Toxicology and Applied Pharmacology. 187: 168-77. PMID 12662900  0.76
2003 Espandiari P, Glauert HP, Lehmler HJ, Lee EY, Srinivasan C, Robertson LW. Polychlorinated biphenyls as initiators in liver carcinogenesis: resistant hepatocyte model. Toxicology and Applied Pharmacology. 186: 55-62. PMID 12583993  0.76
2003 Arif JM, Lehmler HJ, Robertson LW, Gupta RC. Interaction of benzoquinone- and hydroquinone-derivatives of lower chlorinated biphenyls with DNA and nucleotides in vitro. Chemico-Biological Interactions. 142: 307-16. PMID 12453668  0.76
2002 Tampal N, Lehmler HJ, Espandiari P, Malmberg T, Robertson LW. Glucuronidation of hydroxylated polychlorinated biphenyls (PCBs). Chemical Research in Toxicology. 15: 1259-66. PMID 12387623  0.76
2002 Hennig B, Meerarani P, Slim R, Toborek M, Daugherty A, Silverstone AE, Robertson LW. Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence. Toxicology and Applied Pharmacology. 181: 174-83. PMID 12079426  0.6
2002 Fadhel Z, Lu Z, Robertson LW, Glauert HP. Effect of 3,3',4,4'-tetrachlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl on the induction of hepatic lipid peroxidation and cytochrome P-450 associated enzyme activities in rats. Toxicology. 175: 15-25. PMID 12049832  0.44
2002 Hennig B, Hammock BD, Slim R, Toborek M, Saraswathi V, Robertson LW. PCB-induced oxidative stress in endothelial cells: modulation by nutrients. International Journal of Hygiene and Environmental Health. 205: 95-102. PMID 12018021 DOI: 10.1078/1438-4639-00134  0.6
2002 Tharappel JC, Lee EY, Robertson LW, Spear BT, Glauert HP. Regulation of cell proliferation, apoptosis, and transcription factor activities during the promotion of liver carcinogenesis by polychlorinated biphenyls. Toxicology and Applied Pharmacology. 179: 172-84. PMID 11906247 DOI: 10.1006/taap.2001.9360  0.44
2002 Lehmler HJ, Parkin S, Robertson LW. The three-dimensional structure of 3, 3', 5'-trichloro-4-methoxybiphenyl, a "coplanar" polychlorinated biphenyl (PCB) derivative. Chemosphere. 46: 485-8. PMID 11829405  0.76
2002 Pereg D, Robertson LW, Gupta RC. DNA adduction by polychlorinated biphenyls: adducts derived from hepatic microsomal activation and from synthetic metabolites. Chemico-Biological Interactions. 139: 129-44. PMID 11823002  0.44
2002 Lehmler HJ, Robertson LW, Parkin S, Brock CP. Z' = 4 structure without obvious pseudosymmetry: implications for the formation of solid-state compounds. Acta Crystallographica. Section B, Structural Science. 58: 140-7. PMID 11818662  0.76
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