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Andrew T. Gewirtz - Publications

Affiliations: 
Biological and Biomedical Sciences Emory University, Atlanta, GA 
Area:
Immunology, Virology Biology, Public Health
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Year Citation  Score
2023 Ngo VL, Lieber CM, Kang HJ, Sakamoto K, Kuczma M, Plemper RK, Gewirtz AT. Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection. Biorxiv : the Preprint Server For Biology. PMID 37790571 DOI: 10.1101/2023.09.21.558814  0.31
2023 Kordahi MC, Delaroque C, Bredèche MF, Gewirtz AT, Chassaing B. Vaccination against microbiota motility protects mice from the detrimental impact of dietary emulsifier consumption. Plos Biology. 21: e3002289. PMID 37725584 DOI: 10.1371/journal.pbio.3002289  0.347
2020 Viennois E, Bretin A, Dubé PE, Maue AC, Dauriat CJG, Barnich N, Gewirtz AT, Chassaing B. Dietary Emulsifiers Directly Impact Adherent-Invasive E. coli Gene Expression to Drive Chronic Intestinal Inflammation. Cell Reports. 33: 108229. PMID 33027647 DOI: 10.1016/j.celrep.2020.108229  0.306
2020 Zou J, Zhao X, Shi Z, Zhang Z, Vijay-Kumar M, Chassaing B, Gewirtz AT. Critical role of innate immunity to flagellin in absence of adaptive immunity. The Journal of Infectious Diseases. PMID 32830227 DOI: 10.1093/Infdis/Jiaa521  0.334
2020 Powell DN, Swimm A, Sonowal R, Bretin A, Gewirtz AT, Jones RM, Kalman D. Indoles from the commensal microbiota act via the AHR and IL-10 to tune the cellular composition of the colonic epithelium during aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 32817517 DOI: 10.1073/Pnas.2003004117  0.383
2020 Johnson EL, Heaver SL, Waters JL, Kim BI, Bretin A, Goodman AL, Gewirtz AT, Worgall TS, Ley RE. Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels. Nature Communications. 11: 2471. PMID 32424203 DOI: 10.1038/S41467-020-16274-W  0.329
2020 Golonka RM, Saha P, Yeoh BS, Chattopadhay S, Gewirtz AT, Joe B, Vijay-Kumar M. Harnessing Innate Immunity to Eliminate SARS-CoV-2 and Ameliorate COVID-19 Disease. Physiological Genomics. PMID 32275178 DOI: 10.1152/Physiolgenomics.00033.2020  0.322
2020 Adeshirlarijaney A, Gewirtz AT. Considering gut microbiota in treatment of type 2 diabetes mellitus. Gut Microbes. 1-12. PMID 32005089 DOI: 10.1080/19490976.2020.1717719  0.301
2020 Mills RH, Wozniak JM, Vrbanac A, Campeau A, Chassaing B, Gewirtz A, Knight R, Gonzalez DJ. Organ level protein networks as a reference for the host effects of the microbiome. Genome Research. PMID 31992612 DOI: 10.1101/Gr.256875.119  0.305
2020 Abo H, Chassaing B, Harusato A, Quiros M, Brazil JC, Ngo VL, Viennois E, Merlin D, Gewirtz AT, Nusrat A, Denning TL. Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration. Nature Communications. 11: 513. PMID 31980634 DOI: 10.1038/S41467-019-14258-Z  0.38
2020 Mills R, Dulai P, Vázquez-Baeza Y, Zhu Q, Humphrey G, DeRight Goldasich L, Quinn R, Gewirtz A, Chassaing B, Chu H, Sandborn W, Dorrestein P, Knight R, Gonzalez D. OP31 Meta–omics reveals microbiome-driven proteolysis as a contributing factor to the severity of ulcerative colitis disease activity Journal of Crohn's and Colitis. 14: S030-S031. DOI: 10.1093/Ecco-Jcc/Jjz203.030  0.349
2020 Bretin A, Zou J, Pellizzon M, Chassaing B, Gewirtz AT. Tu1260 PSYLLIUM FIBER INDUCES UNIQUE CHANGES IN MICROBIOTA AND COLON GENE EXPRESSION, CHANGES THAT MEDIATE ITS PROTECTION AGAINST INFLAMMATION AND METABOLIC SYNDROME Gastroenterology. 158: S-1035-S-1036. DOI: 10.1016/S0016-5085(20)33270-4  0.322
2019 Tran HQ, Ley RE, Gewirtz AT, Chassaing B. Flagellin-elicited adaptive immunity suppresses flagellated microbiota and vaccinates against chronic inflammatory diseases. Nature Communications. 10: 5650. PMID 31827095 DOI: 10.1038/S41467-019-13538-Y  0.407
2019 Rolhion N, Chassaing B, Nahori MA, de Bodt J, Moura A, Lecuit M, Dussurget O, Bérard M, Marzorati M, Fehlner-Peach H, Littman DR, Gewirtz AT, Van de Wiele T, Cossart P. A Listeria monocytogenes Bacteriocin Can Target the Commensal Prevotella copri and Modulate Intestinal Infection. Cell Host & Microbe. 26: 691-701.e5. PMID 31726031 DOI: 10.1016/J.Chom.2019.10.016  0.376
2019 Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur MS, Das J, Wang H, Guthmiller J, Zheng NY, Huang M, Uphadhyay AA, Gardinassi L, Petitdemange C, McCullough MP, ... ... Gewirtz AT, et al. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 178: 1313-1328.e13. PMID 31491384 DOI: 10.1016/J.Cell.2019.08.010  0.362
2019 Viennois E, Chassaing B, Tahsin A, Pujada A, Wang L, Gewirtz AT, Merlin D. Host-derived fecal microRNAs can indicate gut microbiota healthiness and ability to induce inflammation. Theranostics. 9: 4542-4557. PMID 31285778 DOI: 10.7150/Thno.35282  0.318
2019 Ko EJ, Lee Y, Lee YT, Jung YJ, Ngo VL, Kim MC, Kim KH, Wang BZ, Gewirtz AT, Kang SM. Flagellin-expressing virus-like particles exhibit adjuvant effects on promoting IgG isotype-switched long-lasting antibody induction and protection of influenza vaccines in CD4-deficient mice. Vaccine. PMID 31101421 DOI: 10.1016/J.Vaccine.2019.05.018  0.313
2019 Yeoh BS, Gewirtz AT, Vijay-Kumar M. Adaptive Immunity Induces Tolerance to Flagellin by Attenuating TLR5 and NLRC4-Mediated Innate Immune Responses. Frontiers in Cellular and Infection Microbiology. 9: 29. PMID 30838179 DOI: 10.3389/Fcimb.2019.00029  0.404
2019 Viennois E, Gewirtz AT, Chassaing B. Chronic inflammatory diseases: Are we ready for microbiota-based dietary intervention? Cellular and Molecular Gastroenterology and Hepatology. PMID 30836147 DOI: 10.1016/J.Jcmgh.2019.02.008  0.353
2019 Harusato A, Viennois E, Etienne-Mesmin L, Matsuyama S, Abo H, Osuka S, Lukacs NW, Naito Y, Itoh Y, Li JD, Merlin D, Gewirtz AT, Denning TL. Early-life microbiota exposure restricts myeloid-derived suppressor cell-driven colonic tumorigenesis. Cancer Immunology Research. PMID 30782668 DOI: 10.1158/2326-6066.Cir-18-0444  0.399
2019 Singh V, Yeoh BS, Walker RE, Xiao X, Saha P, Golonka RM, Cai J, Bretin ACA, Cheng X, Liu Q, Flythe MD, Chassaing B, Shearer GC, Patterson AD, Gewirtz AT, et al. Microbiota fermentation-NLRP3 axis shapes the impact of dietary fibres on intestinal inflammation. Gut. PMID 30670576 DOI: 10.1136/Gutjnl-2018-316250  0.365
2018 Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW. Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. Nature. 560: 489-493. PMID 30089902 DOI: 10.1038/S41586-018-0395-5  0.397
2018 Chassaing B, Gewirtz AT. Mice harboring pathobiont-free microbiota do not develop intestinal inflammation that normally results from an innate immune deficiency. Plos One. 13: e0195310. PMID 29617463 DOI: 10.1371/Journal.Pone.0195310  0.425
2018 Chassaing B, Gewirtz AT. Not so Splendid for the Gut Microbiota. Inflammatory Bowel Diseases. PMID 29554295 DOI: 10.1093/Ibd/Izy072  0.367
2018 Shi Z, Gewirtz AT. Together Forever: Bacterial-Viral Interactions in Infection and Immunity. Viruses. 10. PMID 29534424 DOI: 10.3390/V10030122  0.366
2018 Fields CT, Chassaing B, Castillo-Ruiz A, Osan R, Gewirtz AT, de Vries GJ. Effects of gut-derived endotoxin on anxiety-like and repetitive behaviors in male and female mice. Biology of Sex Differences. 9: 7. PMID 29351816 DOI: 10.1186/S13293-018-0166-X  0.313
2017 Zhang B, Oyewole-Said D, Zou J, Willliams IR, Gewirtz AT. TLR5 signaling in murine bone marrow induces hematopoietic progenitor cell proliferation and aids survival from radiation. Blood Advances. 1: 1796-1806. PMID 29296826 DOI: 10.1182/Bloodadvances.2017006981  0.326
2017 Zou J, Chassaing B, Singh V, Pellizzon M, Ricci M, Fythe MD, Kumar MV, Gewirtz AT. Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health. Cell Host & Microbe. PMID 29276170 DOI: 10.1016/J.Chom.2017.11.003  0.337
2017 Chassaing B, Vijay-Kumar M, Gewirtz AT. How diet can impact gut microbiota to promote or endanger health. Current Opinion in Gastroenterology. 33: 417-421. PMID 29019865 DOI: 10.1097/Mog.0000000000000401  0.323
2017 Castillo-Ruiz A, Mosley M, George AJ, Mussaji LF, Fullerton EF, Ruszkowski EM, Jacobs AJ, Gewirtz AT, Chassaing B, Forger NG. The microbiota influences cell death and microglial colonization in the perinatal mouse brain. Brain, Behavior, and Immunity. PMID 28890156 DOI: 10.1016/J.Bbi.2017.08.027  0.357
2017 Chassaing B, Raja SM, Lewis JD, Srinivasan S, Gewirtz AT. Colonic Microbiota Encroachment Correlates With Dysglycemia in Humans. Cellular and Molecular Gastroenterology and Hepatology. 4: 205-221. PMID 28649593 DOI: 10.1016/J.Jcmgh.2017.04.001  0.366
2017 Harusato A, Abo H, Ngo VL, Yi SW, Mitsutake K, Osuka S, Kohlmeier JE, Li JD, Gewirtz AT, Nusrat A, Denning TL. IL-36γ signaling controls the induced regulatory T cell-Th9 cell balance via NFκB activation and STAT transcription factors. Mucosal Immunology. PMID 28327619 DOI: 10.1038/Mi.2017.21  0.341
2017 Chassaing B, Van de Wiele T, De Bodt J, Marzorati M, Gewirtz AT. Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation. Gut. PMID 28325746 DOI: 10.1136/Gutjnl-2016-313099  0.395
2017 Etienne-Mesmin L, Chassaing B, Gewirtz AT. Tryptophan: A gut microbiota-derived metabolites regulating inflammation. World Journal of Gastrointestinal Pharmacology and Therapeutics. 8: 7-9. PMID 28217370 DOI: 10.4292/Wjgpt.V8.I1.7  0.411
2017 Chassaing B, Van de Wiele T, Gewirtz A. O-013 Dietary Emulsifiers Directly Impact the Human Gut Microbiota Increasing Its Pro-inflammatory Potential and Ability to Induce Intestinal Inflammation. Inflammatory Bowel Diseases. 23: S5. PMID 28125561 DOI: 10.1097/01.Mib.0000512523.29952.6F  0.398
2017 Viennois E, Chassaing B, Gewirtz AT, Merlin D. Pept1-Knock Out Mice Harbor a Protective Microbiota Beneficial Against Colitis and Colitis-Associated Cancer Gastroenterology. 152: S154. DOI: 10.1016/S0016-5085(17)30839-9  0.321
2017 Chassaing B, Gewirtz AT. Pathobiont-Free Microbiota Protects Against Gut Inflammation Induced by an Innate Immune Deficiency or Dietary Perturbant of the Microbiota Gastroenterology. 152: S32. DOI: 10.1016/S0016-5085(17)30473-0  0.404
2016 Etienne-Mesmin L, Vijay-Kumar M, Gewirtz AT, Chassaing B. Hepatocyte Toll-Like Receptor 5 Promotes Bacterial Clearance and Protects Mice Against High-Fat Diet-Induced Liver Disease. Cellular and Molecular Gastroenterology and Hepatology. 2: 584-604. PMID 28090564 DOI: 10.1016/J.Jcmgh.2016.04.007  0.37
2016 Reichardt F, Chassaing B, Nezami BG, Li G, Tabatabavakili S, Mwangi S, Uppal K, Liang B, Vijay-Kumar M, Jones D, Gewirtz AT, Srinivasan S. Western diet induces colonic nitrergic myenteric neuropathy and dysmotility in mice via saturated fatty acid- and LPS-induced TLR4 signaling. The Journal of Physiology. PMID 28000223 DOI: 10.1113/Jp273269  0.356
2016 Floyd M, Winn M, Cullen C, Sil P, Chassaing B, Yoo DG, Gewirtz AT, Goldberg JB, McCarter LL, Rada B. Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa. Plos Pathogens. 12: e1005987. PMID 27855208 DOI: 10.1371/Journal.Ppat.1005987  0.351
2016 Viennois E, Merlin D, Gewirtz AT, Chassaing B. Dietary emulsifier-induced low-grade inflammation promotes colon carcinogenesis. Cancer Research. PMID 27821485 DOI: 10.1158/0008-5472.Can-16-1359  0.364
2016 Kanhere M, Chassaing B, Gewirtz AT, Tangpricha V. Role of vitamin D on gut microbiota in cystic fibrosis. The Journal of Steroid Biochemistry and Molecular Biology. PMID 27818276 DOI: 10.1016/J.Jsbmb.2016.11.001  0.313
2016 Guerrant RL, Leite AM, Pinkerton R, Medeiros PH, Cavalcante PA, DeBoer M, Kosek M, Duggan C, Gewirtz A, Kagan JC, Gauthier AE, Swann J, Mayneris-Perxachs J, Bolick DT, Maier EA, et al. Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil. Plos One. 11: e0158772. PMID 27690129 DOI: 10.1371/Journal.Pone.0158772  0.304
2016 Flannigan KL, Ngo VL, Geem D, Harusato A, Hirota SA, Parkos CA, Lukacs NW, Nusrat A, Gaboriau-Routhiau V, Cerf-Bensussan N, Gewirtz AT, Denning TL. IL-17A-mediated neutrophil recruitment limits expansion of segmented filamentous bacteria. Mucosal Immunology. PMID 27624780 DOI: 10.1038/Mi.2016.80  0.373
2016 Bian Z, Shi L, Guo YL, Lv Z, Tang C, Niu S, Tremblay A, Venkataramani M, Culpepper C, Li L, Zhou Z, Mansour A, Zhang Y, Gewirtz A, Kidder K, et al. Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 27578867 DOI: 10.1073/Pnas.1521069113  0.337
2016 Singh V, Yeoh BS, Chassaing B, Zhang B, Saha P, Xiao X, Awasthi D, Shashidharamurthy R, Dikshit M, Gewirtz A, Vijay-Kumar M. Microbiota-inducible Innate Immune, Siderophore Binding Protein Lipocalin 2 is Critical for Intestinal Homeostasis. Cellular and Molecular Gastroenterology and Hepatology. 2: 482-498.e6. PMID 27458605 DOI: 10.1016/J.Jcmgh.2016.03.007  0.419
2016 Anitha M, Reichardt F, Tabatabavakili S, Nezami BG, Chassaing B, Mwangi S, Vijay-Kumar M, Gewirtz A, Srinivasan S. Intestinal dysbiosis contributes to the delayed gastrointestinal transit in high-fat diet fed mice. Cellular and Molecular Gastroenterology and Hepatology. 2: 328-339. PMID 27446985 DOI: 10.1016/J.Jcmgh.2015.12.008  0.319
2016 Ley RE, Gewirtz AT. Corralling Colonic Flagellated Microbiota. The New England Journal of Medicine. 375: 85-7. PMID 27406353 DOI: 10.1056/Nejmcibr1604801  0.343
2016 Li JY, Chassaing B, Tyagi AM, Vaccaro C, Luo T, Adams J, Darby TM, Weitzmann MN, Mulle JG, Gewirtz AT, Jones RM, Pacifici R. Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. The Journal of Clinical Investigation. PMID 27111232 DOI: 10.1172/Jci86062  0.356
2016 Song J, Wilhelm CL, Wangdi T, Maira-Litran T, Lee SJ, Raetz M, Sturge CR, Mirpuri J, Pei J, Grishin NV, McSorley SJ, Gewirtz AT, Bäumler AJ, Pier GB, Galán JE, et al. Absence of TLR11 in Mice Does Not Confer Susceptibility to Salmonella Typhi. Cell. 164: 827-828. PMID 26919416 DOI: 10.1016/J.Cell.2016.02.015  0.32
2016 Chassaing B, Gewirtz AT. Has provoking microbiota aggression driven the obesity epidemic? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 38: 122-8. PMID 26749135 DOI: 10.1002/Bies.201500116  0.326
2016 Chassaing B, Tran H, Gewirtz AT. Su1885 Colitis Vaccine: Flagellin-Elicited Immunity Keeps Motile Bacteria In-Check and Protects Against Intestinal Inflammation Gastroenterology. 150: S579. DOI: 10.1016/S0016-5085(16)31984-9  0.339
2016 Chassaing B, van De Wiele T, Gewirtz AT. 88 Dietary Emulsifiers Directly Impact the Human Gut Microbiota Increasing Its Pro-Inflammatory Potential Gastroenterology. 150: S22. DOI: 10.1016/S0016-5085(16)30199-8  0.347
2015 Gewirtz AT. Deciphering the Role of Mesenteric Fat in Inflammatory Bowel Disease. Cellular and Molecular Gastroenterology and Hepatology. 1: 352-353. PMID 28210686 DOI: 10.1016/J.Jcmgh.2015.05.004  0.311
2015 Rios D, Wood MB, Li J, Chassaing B, Gewirtz AT, Williams IR. Antigen sampling by intestinal M cells is the principal pathway initiating mucosal IgA production to commensal enteric bacteria. Mucosal Immunology. PMID 26601902 DOI: 10.1038/Mi.2015.121  0.383
2015 Medina-Contreras O, Harusato A, Nishio H, Flannigan KL, Ngo V, Leoni G, Neumann PA, Geem D, Lili LN, Ramadas RA, Chassaing B, Gewirtz AT, Kohlmeier JE, Parkos CA, Towne JE, et al. Cutting Edge: IL-36 Receptor Promotes Resolution of Intestinal Damage. Journal of Immunology (Baltimore, Md. : 1950). PMID 26590314 DOI: 10.4049/Jimmunol.1501312  0.332
2015 Singh V, Chassaing B, Zhang L, San Yeoh B, Xiao X, Kumar M, Baker MT, Cai J, Walker R, Borkowski K, Harvatine KJ, Singh N, Shearer GC, Ntambi JM, Joe B, ... ... Gewirtz AT, et al. Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice. Cell Metabolism. PMID 26525535 DOI: 10.1016/J.Cmet.2015.09.028  0.328
2015 Chassaing B, Miles-Brown J, Pellizzon M, Ulman E, Ricci M, Zhang L, Patterson AD, Vijay-Kumar M, Gewirtz AT. Lack of soluble fiber drives diet-induced adiposity in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 309: G528-41. PMID 26185332 DOI: 10.1152/Ajpgi.00172.2015  0.32
2015 Singh V, Yeoh BS, Carvalho F, Gewirtz AT, Vijay-Kumar M. Proneness of TLR5 Deficient Mice to Develop Colitis is Microbiota Dependent. Gut Microbes. 0. PMID 26067589 DOI: 10.1080/19490976.2015.1060390  0.401
2015 Chassaing B, Koren O, Goodrich JK, Poole AC, Srinivasan S, Ley RE, Gewirtz AT. Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature. 519: 92-6. PMID 25731162 DOI: 10.1038/Nature14232  0.39
2015 Thapa M, Chinnadurai R, Velazquez VM, Tedesco D, Elrod E, Han JH, Sharma P, Ibegbu C, Gewirtz A, Anania F, Pulendran B, Suthar MS, Grakoui A. Liver fibrosis occurs through dysregulation of MyD88-dependent innate B-cell activity. Hepatology (Baltimore, Md.). 61: 2067-79. PMID 25711908 DOI: 10.1002/Hep.27761  0.347
2015 Uchiyama R, Chassaing B, Zhang B, Gewirtz AT. MyD88-mediated TLR signaling protects against acute rotavirus infection while inflammasome cytokines direct Ab response. Innate Immunity. 21: 416-28. PMID 25213347 DOI: 10.1177/1753425914547435  0.41
2015 Galloway DP, Troutt ML, Kocoshis SA, Gewirtz AT, Ziegler TR, Cole CR. Increased Anti-Flagellin and Anti-Lipopolysaccharide Immunoglobulins in Pediatric Intestinal Failure: Associations With Fever and Central Line-Associated Bloodstream Infections. Jpen. Journal of Parenteral and Enteral Nutrition. 39: 562-8. PMID 24898211 DOI: 10.1177/0148607114537073  0.308
2015 Etienne-Mesmin L, Chassaing B, Gewirtz AT. Su1802 Hepatocyte TLR5 Protects Against Bacterial Infection and High-Fat Diet Induced Liver Disease Gastroenterology. 148: S-1054-S-1055. DOI: 10.1016/S0016-5085(15)33599-X  0.324
2014 Zhang B, Chassaing B, Shi Z, Uchiyama R, Zhang Z, Denning TL, Crawford SE, Pruijssers AJ, Iskarpatyoti JA, Estes MK, Dermody TS, Ouyang W, Williams IR, Vijay-Kumar M, Gewirtz AT. Viral infection. Prevention and cure of rotavirus infection via TLR5/NLRC4-mediated production of IL-22 and IL-18. Science (New York, N.Y.). 346: 861-5. PMID 25395539 DOI: 10.1126/Science.1256999  0.391
2014 Leifer CA, McConkey C, Li S, Chassaing B, Gewirtz AT, Ley RE. Linking genetic variation in human Toll-like receptor 5 genes to the gut microbiome's potential to cause inflammation. Immunology Letters. 162: 3-9. PMID 25284610 DOI: 10.1016/J.Imlet.2014.07.017  0.409
2014 Oh JZ, Ravindran R, Chassaing B, Carvalho FA, Maddur MS, Bower M, Hakimpour P, Gill KP, Nakaya HI, Yarovinsky F, Sartor RB, Gewirtz AT, Pulendran B. TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination. Immunity. 41: 478-92. PMID 25220212 DOI: 10.1016/J.Immuni.2014.08.009  0.325
2014 Chassaing B, Ley RE, Gewirtz AT. Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice. Gastroenterology. 147: 1363-77.e17. PMID 25172014 DOI: 10.1053/J.Gastro.2014.08.033  0.407
2014 Hossain MS, Ramachandiran S, Gewirtz AT, Waller EK. Recombinant TLR5 agonist CBLB502 promotes NK cell-mediated anti-CMV immunity in mice. Plos One. 9: e96165. PMID 24879439 DOI: 10.1371/Journal.Pone.0096165  0.412
2014 Xiao B, Laroui H, Viennois E, Ayyadurai S, Charania MA, Zhang Y, Zhang Z, Baker MT, Zhang B, Gewirtz AT, Merlin D. Nanoparticles with surface antibody against CD98 and carrying CD98 small interfering RNA reduce colitis in mice. Gastroenterology. 146: 1289-300.e1-19. PMID 24503126 DOI: 10.1053/J.Gastro.2014.01.056  0.303
2014 Uchiyama R, Chassaing B, Zhang B, Gewirtz AT. Antibiotic treatment suppresses rotavirus infection and enhances specific humoral immunity. The Journal of Infectious Diseases. 210: 171-82. PMID 24436449 DOI: 10.1093/Infdis/Jiu037  0.307
2014 Chassaing B, Gewirtz AT. Gut microbiota, low-grade inflammation, and metabolic syndrome. Toxicologic Pathology. 42: 49-53. PMID 24285672 DOI: 10.1177/0192623313508481  0.379
2014 Chassaing B, Koren O, Carvalho FA, Ley RE, Gewirtz AT. AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition. Gut. 63: 1069-80. PMID 23896971 DOI: 10.1136/Gutjnl-2013-304909  0.426
2014 Chassaing B, Etienne-Mesmin L, Gewirtz AT. Microbiota-liver axis in hepatic disease. Hepatology (Baltimore, Md.). 59: 328-39. PMID 23703735 DOI: 10.1002/Hep.26494  0.329
2014 Chassaing B, Gewirtz AT. Sa1745 Food Additives Promote Intestinal Inflammation in Susceptible Hosts Gastroenterology. 146: S-286. DOI: 10.1016/S0016-5085(14)61016-7  0.331
2014 Chassaing B, Gewirtz AT. Sa1723 Role of Intestinal Epithelial Cell, Dendritic Cell, and Hepatocyte TLR5 in Keeping the Microbiota In-check and Protecting the Gut Gastroenterology. 146: S-281-S-282. DOI: 10.1016/S0016-5085(14)60994-X  0.386
2014 Uchiyama R, Gewirtz AT. 74 Antibiotic Treatment Suppresses Rotavirus Infection and Enhances RV-Specific Immunity Gastroenterology. 146: S-21. DOI: 10.1016/S0016-5085(14)60074-3  0.3
2014 Uchiyama R, Gewirtz AT. 21 MyD88 Is Important for Rotavirus Infection Containment and Specific Adaptive Responses Gastroenterology. 146: S-7. DOI: 10.1016/S0016-5085(14)60021-4  0.413
2013 Cullender TC, Chassaing B, Janzon A, Kumar K, Muller CE, Werner JJ, Angenent LT, Bell ME, Hay AG, Peterson DA, Walter J, Vijay-Kumar M, Gewirtz AT, Ley RE. Innate and adaptive immunity interact to quench microbiome flagellar motility in the gut. Cell Host & Microbe. 14: 571-81. PMID 24237702 DOI: 10.1016/J.Chom.2013.10.009  0.421
2013 Ursell LK, Van Treuren W, Metcalf JL, Pirrung M, Gewirtz A, Knight R. Replenishing our defensive microbes. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 810-7. PMID 23836415 DOI: 10.1002/Bies.201300018  0.305
2013 Aitken JD, Gewirtz AT. Gut microbiota in 2012: Toward understanding and manipulating the gut microbiota. Nature Reviews. Gastroenterology & Hepatology. 10: 72-4. PMID 23296245 DOI: 10.1038/Nrgastro.2012.252  0.361
2013 Norris V, Molina F, Gewirtz AT. Hypothesis: bacteria control host appetites. Journal of Bacteriology. 195: 411-6. PMID 23144247 DOI: 10.1128/Jb.01384-12  0.338
2013 Chassaing B, Koren O, Carvalho FA, Ley RE, Gewirtz AT. Tu2024 AIEC Instigates Chronic Colitis by Altering Microbiota Composition and Its Inherent Pro-Inflammatory Potential Gastroenterology. 144: S-907. DOI: 10.1016/S0016-5085(13)63380-6  0.345
2012 Chassaing B, Aitken JD, Gewirtz AT, Vijay-Kumar M. Gut microbiota drives metabolic disease in immunologically altered mice. Advances in Immunology. 116: 93-112. PMID 23063074 DOI: 10.1016/B978-0-12-394300-2.00003-X  0.373
2012 Chassaing B, Srinivasan G, Delgado MA, Young AN, Gewirtz AT, Vijay-Kumar M. Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation. Plos One. 7: e44328. PMID 22957064 DOI: 10.1371/Journal.Pone.0044328  0.405
2012 Carvalho FA, Koren O, Goodrich JK, Johansson ME, Nalbantoglu I, Aitken JD, Su Y, Chassaing B, Walters WA, González A, Clemente JC, Cullender TC, Barnich N, Darfeuille-Michaud A, Vijay-Kumar M, ... ... Gewirtz AT, et al. Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice. Cell Host & Microbe. 12: 139-52. PMID 22863420 DOI: 10.1016/J.Chom.2012.07.004  0.422
2012 Srinivasan G, Aitken JD, Zhang B, Carvalho FA, Chassaing B, Shashidharamurthy R, Borregaard N, Jones DP, Gewirtz AT, Vijay-Kumar M. Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. Journal of Immunology (Baltimore, Md. : 1950). 189: 1911-9. PMID 22786765 DOI: 10.4049/Jimmunol.1200892  0.333
2012 Anitha M, Vijay-Kumar M, Sitaraman SV, Gewirtz AT, Srinivasan S. Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling. Gastroenterology. 143: 1006-16.e4. PMID 22732731 DOI: 10.1053/J.Gastro.2012.06.034  0.348
2012 Ingersoll SA, Laroui H, Kolachala VL, Wang L, Garg P, Denning TL, Gewirtz AT, Merlin D, Sitaraman SV. A(₂B)AR expression in non-immune cells plays an important role in the development of murine colitis. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 44: 819-26. PMID 22721840 DOI: 10.1016/J.Dld.2012.05.013  0.362
2012 Carvalho FA, Nalbantoglu I, Aitken JD, Uchiyama R, Su Y, Doho GH, Vijay-Kumar M, Gewirtz AT. Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges. Mucosal Immunology. 5: 288-98. PMID 22318495 DOI: 10.1038/Mi.2012.8  0.439
2012 Carvalho FA, Aitken JD, Vijay-Kumar M, Gewirtz AT. Toll-like receptor-gut microbiota interactions: perturb at your own risk! Annual Review of Physiology. 74: 177-98. PMID 22035346 DOI: 10.1146/Annurev-Physiol-020911-153330  0.385
2012 Frias AH, Jones RM, Fifadara NH, Vijay-Kumar M, Gewirtz AT. Rotavirus-induced IFN-β promotes anti-viral signaling and apoptosis that modulate viral replication in intestinal epithelial cells. Innate Immunity. 18: 294-306. PMID 21733977 DOI: 10.1177/1753425911401930  0.762
2012 Carvalho FA, Nalbantoglu I, Ortega-Fernandez S, Aitken JD, Su Y, Koren O, Walters WA, Knight R, Ley RE, Vijay-Kumar M, Gewirtz AT. Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis. Gut. 61: 373-84. PMID 21646247 DOI: 10.1136/Gut.2011.240556  0.394
2012 Hossain MS, Gewirtz AT, Waller EK. Distinct IFN-Gamma Dependent Effect of the TLR5 Agonist, Flagellin On NK and CD4+ T Cell Immunity Against CMV Blood. 120: 255-255. DOI: 10.1182/Blood.V120.21.255.255  0.41
2012 Carvalho F, Koren O, Chassaing B, Darfeuille-Michaud A, Knight R, Ley R, Gewirtz A. Colitis in TLR5-deficiency Mice: Role of the Microbiota Inflammatory Bowel Diseases. 18: S113-S114. DOI: 10.1097/00054725-201212001-00292  0.356
2012 Liu H, Patel NR, Gewirtz AT, Merlin D, Sitaraman SV, Garg P. 1073 Cell-Specific Overexpression of MMP9 in the Colonic Epithelium is Associated With Increased Level of PRO-Inflammatory Chemokine Kc, Which in Turn Mediates Inflammation in Acute Colitis Gastroenterology. 142: S-191. DOI: 10.1016/S0016-5085(12)60716-1  0.353
2011 Hossain MS, Jaye DL, Pollack BP, Farris AB, Tselanyane ML, David E, Roback JD, Gewirtz AT, Waller EK. Flagellin, a TLR5 agonist, reduces graft-versus-host disease in allogeneic hematopoietic stem cell transplantation recipients while enhancing antiviral immunity. Journal of Immunology (Baltimore, Md. : 1950). 187: 5130-40. PMID 22013117 DOI: 10.4049/Jimmunol.1101334  0.335
2011 Garg P, Jeppsson S, Dalmasso G, Ghaleb AM, McConnell BB, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. Notch1 regulates the effects of matrix metalloproteinase-9 on colitis-associated cancer in mice. Gastroenterology. 141: 1381-92. PMID 21723221 DOI: 10.1053/J.Gastro.2011.06.056  0.324
2011 Kwon S, Gewirtz AT, Hurley DJ, Robertson TP, Moore JN, Vandenplas ML. Disparities in TLR5 expression and responsiveness to flagellin in equine neutrophils and mononuclear phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 186: 6263-70. PMID 21518971 DOI: 10.4049/Jimmunol.1003824  0.359
2011 Vijay-Kumar M, Aitken JD, Carvalho FA, Ziegler TR, Gewirtz AT, Ganji V. Loss of function mutation in toll-like receptor-4 does not offer protection against obesity and insulin resistance induced by a diet high in trans fat in mice. Journal of Inflammation (London, England). 8: 2. PMID 21314942 DOI: 10.1186/1476-9255-8-2  0.318
2011 Jones RM, Sloane VM, Wu H, Luo L, Kumar A, Kumar MV, Gewirtz AT, Neish AS. Flagellin administration protects gut mucosal tissue from irradiation-induced apoptosis via MKP-7 activity. Gut. 60: 648-57. PMID 21199832 DOI: 10.1136/Gut.2010.223891  0.362
2011 Carvalho FA, Aitken JD, Gewirtz AT, Vijay-Kumar M. TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage. Mucosal Immunology. 4: 102-11. PMID 20844479 DOI: 10.1038/Mi.2010.57  0.338
2011 Hossain MS, Jaye DL, Pollack BP, Farr AB, Roback J, Gewirtz AT, Waller EK. Flagellin, a TLR5 Agonist, Reduces GvHD in Allogeneic HSCT Recipients While Enhancing Anti-Viral Immunity: A Novel Therapeutic Approach Blood. 118: 144-144. DOI: 10.1182/Blood.V118.21.144.144  0.326
2011 Aitken JD, Carvalho FA, Fifadara N, Ganesh T, Gewirtz AT, Vijay-Kumar M. Lipocalin-2 Deficiency Increases Gut Bacterial Burden and Excerbates Dextran Sulfate Sodium (DSS) Induced Murine Colitis Gastroenterology. 140: S-496. DOI: 10.1016/S0016-5085(11)62051-9  0.382
2011 Garg P, Patel NR, Laroui H, Gewirtz AT, Merlin D, Sitaraman SV. Constitutive Expression of MMP-9 in Intestinal Epithelial Cells Worsens Acute Colitis in Mice Gastroenterology. 140: S-143. DOI: 10.1016/S0016-5085(11)60581-7  0.339
2011 Carvalho FA, Vijay-Kumar M, Aitken JD, Barnich N, Darfeuille-Michaud A, Gewirtz AT. Coordinate Detection of Flagellin by TLR5 and NLRC4 Mediate Rapid Clearance of AIEC LF82 and Limit Gut Inflammation Gastroenterology. 140: S-115. DOI: 10.1016/S0016-5085(11)60466-6  0.354
2011 Carvalho FA, Aitken JD, Vijay-Kumar M, Gewirtz AT. Cytosolic Flagellin Receptor NLRC4 Plays a Key Role in Host Defense Against Orally Administered Inflammation-Associated Bacteria Gastroenterology. 140: S-30. DOI: 10.1016/S0016-5085(11)60115-7  0.351
2011 Hossain M, Gewirtz A, Roback J, Waller E. Flagellin Reduces GvHD Through Early Immunosuppression Induced by the flagellin-TLR5 Immune Interaction of Host Cells in Allogeneic HSCT Recipients Biology of Blood and Marrow Transplantation. 17: S303. DOI: 10.1016/J.Bbmt.2010.12.447  0.357
2010 Vijay-Kumar M, Carvalho FA, Aitken JD, Fifadara NH, Gewirtz AT. TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin. European Journal of Immunology. 40: 3528-34. PMID 21072873 DOI: 10.1002/Eji.201040421  0.407
2010 Titanji K, Velu V, Chennareddi L, Vijay-Kumar M, Gewirtz AT, Freeman GJ, Amara RR. Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques. The Journal of Clinical Investigation. 120: 3878-90. PMID 20972331 DOI: 10.1172/Jci43271  0.313
2010 Castanon-Cervantes O, Wu M, Ehlen JC, Paul K, Gamble KL, Johnson RL, Besing RC, Menaker M, Gewirtz AT, Davidson AJ. Dysregulation of inflammatory responses by chronic circadian disruption. Journal of Immunology (Baltimore, Md. : 1950). 185: 5796-805. PMID 20944004 DOI: 10.4049/Jimmunol.1001026  0.35
2010 Frias AH, Vijay-Kumar M, Gentsch JR, Crawford SE, Carvalho FA, Estes MK, Gewirtz AT. Intestinal epithelia activate anti-viral signaling via intracellular sensing of rotavirus structural components. Mucosal Immunology. 3: 622-32. PMID 20664578 DOI: 10.1038/Mi.2010.39  0.772
2010 Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5. Science (New York, N.Y.). 328: 228-31. PMID 20203013 DOI: 10.1126/Science.1179721  0.339
2010 Cole CR, Frem JC, Schmotzer B, Gewirtz AT, Meddings JB, Gold BD, Ziegler TR. The rate of bloodstream infection is high in infants with short bowel syndrome: relationship with small bowel bacterial overgrowth, enteral feeding, and inflammatory and immune responses. The Journal of Pediatrics. 156: 941-7, 947.e1. PMID 20171649 DOI: 10.1016/J.Jpeds.2009.12.008  0.354
2010 Garg P, Sarma D, Jeppsson S, Patel NR, Gewirtz AT, Merlin D, Sitaraman SV. Matrix metalloproteinase-9 functions as a tumor suppressor in colitis-associated cancer. Cancer Research. 70: 792-801. PMID 20068187 DOI: 10.1158/0008-5472.Can-09-3166  0.305
2010 Frias AH, Vijay-Kumar M, Jones R, Gentsch JR, Estes MK, Gewirtz AT. T1789 Intestinal Epithelia Activate Anti-Viral Signaling by Intracellular Sensing of Rotavirus Structural Components Gastroenterology. 138: S-579. DOI: 10.1016/S0016-5085(10)62667-4  0.749
2010 Kolachala VL, Denning TL, Wang L, Vijay-Kumar M, Gewirtz AT, Merlin D, Sitaraman SV. M1829 Colonic Mucosal A2BR Mediates Pro-Inflammatory Events Gastroenterology. 138: S-427. DOI: 10.1016/S0016-5085(10)61972-5  0.315
2010 Frias AH, Vijay-Kumar M, Jones R, Gewirtz AT. S1768 Epithelia Respond to Rotavirus by Producing Type 1 Ifns That Drive Antiviral Gene Expression and Apoptosis Gastroenterology. 138: S-270. DOI: 10.1016/S0016-5085(10)61238-3  0.736
2010 Carvalho FA, Vijay-Kumar M, Gewirtz AT. S1755 Cytosolic Flagellin Receptor Ipaf Plays a Key Role in Host Defense Against Orally Administered Salmonella Gastroenterology. 138: S-267. DOI: 10.1016/S0016-5085(10)61225-5  0.311
2010 Carvalho FA, Vijay-Kumar M, Gewirtz AT. S1722 Loss of TLR5 Predisposes Mice to TLR4-, Ipaf- And Helicobacter-Independent Colitis in Response to Neutralization of IL-10 Gastroenterology. 138: S-260-S-261. DOI: 10.1016/S0016-5085(10)61192-4  0.345
2010 Carvalho FA, Aitken JD, Sitaraman SV, Gewirtz AT, Vijay-Kumar M. 394 TLR5-Mediated Expression of Endogenous IL-1β Antagonist, Sil-1ra, Protects Against Inflammation Gastroenterology. 138: S-58. DOI: 10.1016/S0016-5085(10)60262-4  0.304
2010 Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi SM, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT. 279 Altered Gut Microbiota in Toll-Like Receptor-5 (TLR5) Deficient Mice Results in Metabolic Syndrome Gastroenterology. 138: S-52. DOI: 10.1016/S0016-5085(10)60237-5  0.336
2010 Hossain M, Gewirtz A, Roback J, Waller E. Flagellin-TLR5 Immune Response: A Novel Mechanism To Reduce GvHD In Allogeneic Hematopoietic Stem Cell Transplantation Biology of Blood and Marrow Transplantation. 16: S160. DOI: 10.1016/J.Bbmt.2009.12.027  0.303
2009 Onyeagocha C, Hossain MS, Kumar A, Jones RM, Roback J, Gewirtz AT. Latent cytomegalovirus infection exacerbates experimental colitis. The American Journal of Pathology. 175: 2034-42. PMID 19815702 DOI: 10.2353/Ajpath.2009.090471  0.375
2009 Scarlett UK, Cubillos-Ruiz JR, Nesbeth YC, Martinez DG, Engle X, Gewirtz AT, Ahonen CL, Conejo-Garcia JR. In situ stimulation of CD40 and Toll-like receptor 3 transforms ovarian cancer-infiltrating dendritic cells from immunosuppressive to immunostimulatory cells. Cancer Research. 69: 7329-37. PMID 19738057 DOI: 10.1158/0008-5472.Can-09-0835  0.34
2009 Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR. Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. The Journal of Clinical Investigation. 119: 2231-44. PMID 19620771 DOI: 10.1172/Jci37716  0.357
2009 Fournier B, Williams IR, Gewirtz AT, Neish AS. Toll-like receptor 5-dependent regulation of inflammation in systemic Salmonella enterica Serovar typhimurium infection. Infection and Immunity. 77: 4121-9. PMID 19596770 DOI: 10.1128/Iai.00656-09  0.425
2009 Theiss AL, Vijay-Kumar M, Obertone TS, Jones DP, Hansen JM, Gewirtz AT, Merlin D, Sitaraman SV. Prohibitin is a novel regulator of antioxidant response that attenuates colonic inflammation in mice. Gastroenterology. 137: 199-208, 208.e1-6. PMID 19327358 DOI: 10.1053/J.Gastro.2009.03.033  0.362
2009 Vijay-Kumar M, Gewirtz AT. Flagellin: key target of mucosal innate immunity. Mucosal Immunology. 2: 197-205. PMID 19242410 DOI: 10.1038/Mi.2009.9  0.385
2009 Sanders CJ, Franchi L, Yarovinsky F, Uematsu S, Akira S, Núñez G, Gewirtz AT. Induction of adaptive immunity by flagellin does not require robust activation of innate immunity European Journal of Immunology. 39: 359-371. PMID 19152336 DOI: 10.1002/Eji.200838804  0.364
2009 Deng J, Ma-Krupa W, Gewirtz AT, Younge BR, Goronzy JJ, Weyand CM. Toll-like receptors 4 and 5 induce distinct types of vasculitis. Circulation Research. 104: 488-95. PMID 19150884 DOI: 10.1161/Circresaha.108.185777  0.346
2009 Vijay-Kumar M, Gewirtz AT. Role of flagellin in Crohn's disease: emblematic of the progress and enigmas in understanding inflammatory bowel disease. Inflammatory Bowel Diseases. 15: 789-95. PMID 19107795 DOI: 10.1002/Ibd.20734  0.369
2009 Tian J, Hao L, Chandra P, Jones DP, Willams IR, Gewirtz AT, Ziegler TR. Dietary glutamine and oral antibiotics each improve indexes of gut barrier function in rat short bowel syndrome. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G348-55. PMID 19095767 DOI: 10.1152/Ajpgi.90233.2008  0.345
2009 Garg P, Patel NR, Vijay-Kumar M, Ravi A, Merlin D, Gewirtz AT, Sitaraman SV. M2004 Deletion of Matrix Metalloproteinase-9 (MMP-9) Increases the Susceptibility for Colon Cancer Gastroenterology. 136: A-465. DOI: 10.1016/S0016-5085(09)62138-7  0.331
2009 Nguyen HTT, Dalmasso G, Yan Y, Powell K, Bhatt S, Kalman D, Gewirtz AT, Sitaraman SV, Merlin D. 556 Pathogenic Bacteria Transcriptionally Induce Colonic PepT1 Expression – An Implication in Modulating Bacterial-Epithelial Interaction Gastroenterology. 136: A-87. DOI: 10.1016/S0016-5085(09)60391-7  0.35
2009 Theiss AL, Vijay-Kumar M, Obertone TS, Jones D, Hansen J, Gewirtz AT, Merlin D, Sitaraman SV. 219 Prohibitin (PHB) Is a Novel Antioxidant That Attenuates Colonic Inflammation in Mice Gastroenterology. 136: A-41. DOI: 10.1016/S0016-5085(09)60190-6  0.345
2008 Vijay-Kumar M, Gewirtz AT. Guardians of the gut: newly appreciated role of epithelial toll-like receptors in protecting the intestine. Gastroenterology. 135: 351-4. PMID 18619968 DOI: 10.1053/J.Gastro.2008.06.064  0.357
2008 Kolachala VL, Ruble BK, Vijay-Kumar M, Wang L, Mwangi S, Figler HE, Figler RA, Srinivasan S, Gewirtz AT, Linden J, Merlin D, Sitaraman SV. Blockade of adenosine A 2B receptors ameliorates murine colitis British Journal of Pharmacology. 155: 127-137. PMID 18536750 DOI: 10.1038/Bjp.2008.227  0.323
2008 Vijay-Kumar M, Aitken JD, Sanders CJ, Frias A, Sloane VM, Xu J, Neish AS, Rojas M, Gewirtz AT. Flagellin treatment protects against chemicals, bacteria, viruses, and radiation. Journal of Immunology (Baltimore, Md. : 1950). 180: 8280-5. PMID 18523294 DOI: 10.4049/Jimmunol.180.12.8280  0.771
2008 Sanders CJ, Moore DA, Williams IR, Gewirtz AT. Both radioresistant and hemopoietic cells promote innate and adaptive immune responses to flagellin. Journal of Immunology (Baltimore, Md. : 1950). 180: 7184-92. PMID 18490717 DOI: 10.4049/Jimmunol.180.11.7184  0.399
2008 Petrof EO, Musch MW, Ciancio M, Sun J, Hobert ME, Claud EC, Gewirtz A, Chang EB. Flagellin is required for salmonella-induced expression of heat shock protein Hsp25 in intestinal epithelium. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G808-18. PMID 18202113 DOI: 10.1152/Ajpgi.00362.2007  0.367
2008 Vijay-Kumar M, Aitken JD, Kumar A, Neish AS, Uematsu S, Akira S, Gewirtz AT. Toll-like receptor 5-deficient mice have dysregulated intestinal gene expression and nonspecific resistance to Salmonella-induced typhoid-like disease Infection and Immunity. 76: 1276-1281. PMID 18195036 DOI: 10.1128/Iai.01491-07  0.409
2008 Vijay-Kumar M, Aitken JD, Gewirtz AT. Toll like receptor-5: protecting the gut from enteric microbes. Seminars in Immunopathology. 30: 11-21. PMID 18066550 DOI: 10.1007/S00281-007-0100-5  0.416
2008 Ziegler TR, Luo M, Estívariz CF, Moore DA, Sitaraman SV, Hao L, Bazargan N, Klapproth JM, Tian J, Galloway JR, Leader LM, Jones DP, Gewirtz AT. Detectable serum flagellin and lipopolysaccharide and upregulated anti-flagellin and lipopolysaccharide immunoglobulins in human short bowel syndrome. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R402-10. PMID 18003793 DOI: 10.1152/Ajpregu.00650.2007  0.301
2007 Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT. Deletion of TLR5 results in spontaneous colitis in mice. The Journal of Clinical Investigation. 117: 3909-21. PMID 18008007 DOI: 10.1172/Jci33084  0.434
2007 Kolachala VL, Bajaj R, Wang L, Yan Y, Ritzenthaler JD, Gewirtz AT, Roman J, Merlin D, Sitaraman SV. Epithelial-derived fibronectin expression, signaling, and function in intestinal inflammation. The Journal of Biological Chemistry. 282: 32965-73. PMID 17855340 DOI: 10.1074/Jbc.M704388200  0.375
2007 Gewirtz AT, Sitaraman SV. In"sight" into immune blindness: Helicobacter pylori-induced gastritis requires T cells primed in the small intestine Peyer's patches. Gastroenterology. 133: 1044-5. PMID 17854610 DOI: 10.1053/J.Gastro.2007.07.044  0.364
2007 Garg P, Ravi A, Patel NR, Roman J, Gewirtz AT, Merlin D, Sitaraman SV. Matrix metalloproteinase-9 regulates MUC-2 expression through its effect on goblet cell differentiation. Gastroenterology. 132: 1877-89. PMID 17484881 DOI: 10.1053/J.Gastro.2007.02.048  0.345
2007 Charrier L, Yan Y, Nguyen HT, Dalmasso G, Laboisse CL, Gewirtz AT, Sitaraman SV, Merlin D. ADAM-15/metargidin mediates homotypic aggregation of human T lymphocytes and heterotypic interactions of T lymphocytes with intestinal epithelial cells. The Journal of Biological Chemistry. 282: 16948-58. PMID 17416588 DOI: 10.1074/Jbc.M700158200  0.328
2007 Vijay-Kumar M, Wu H, Aitken J, Kolachala VL, Neish AS, Sitaraman SV, Gewirtz AT. Activation of toll-like receptor 3 protects against DSS-induced acute colitis. Inflammatory Bowel Diseases. 13: 856-64. PMID 17393379 DOI: 10.1002/Ibd.20142  0.349
2007 Gewirtz AT. TLRs in the Gut. III. Immune responses to flagellin in Crohn's disease: good, bad, or irrelevant? American Journal of Physiology. Gastrointestinal and Liver Physiology. 292: G706-10. PMID 17038626 DOI: 10.1152/Ajpgi.00347.2006  0.34
2007 Garg P, Ravi A, Patel N, Roman J, Gewirtz A, Merlin D, Sitaraman S. Metalloproteinase-9 (MMP-9) regulates intestinal goblet cell specific gene expression Inflammatory Bowel Diseases. 13: 644. DOI: 10.1097/00054725-200705001-00007  0.308
2006 Vijay-Kumar M, Wu H, Jones R, Grant G, Babbin B, King TP, Kelly D, Gewirtz AT, Neish AS. Flagellin suppresses epithelial apoptosis and limits disease during enteric infection. The American Journal of Pathology. 169: 1686-700. PMID 17071592 DOI: 10.2353/Ajpath.2006.060345  0.438
2006 Xicohtencatl-Cortés J, Lyons S, Chaparro AP, Hernández DR, Saldaña Z, Ledesma MA, Rendón MA, Gewirtz AT, Klose KE, Girón JA. Identification of proinflammatory flagellin proteins in supernatants of Vibrio cholerae O1 by proteomics analysis. Molecular & Cellular Proteomics : McP. 5: 2374-83. PMID 16998199 DOI: 10.1074/Mcp.M600228-Mcp200  0.323
2006 Amer A, Franchi L, Kanneganti TD, Body-Malapel M, Ozören N, Brady G, Meshinchi S, Jagirdar R, Gewirtz A, Akira S, Núñez G. Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. The Journal of Biological Chemistry. 281: 35217-23. PMID 16984919 DOI: 10.1074/Jbc.M604933200  0.387
2006 Garg P, Rojas M, Ravi A, Bockbrader K, Epstein S, Vijay-Kumar M, Gewirtz AT, Merlin D, Sitaraman SV. Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis. Journal of Immunology (Baltimore, Md. : 1950). 177: 4103-12. PMID 16951375 DOI: 10.4049/Jimmunol.177.6.4103  0.312
2006 Sanders CJ, Yu Y, Moore DA, Williams IR, Gewirtz AT. Humoral immune response to flagellin requires T cells and activation of innate immunity. Journal of Immunology (Baltimore, Md. : 1950). 177: 2810-8. PMID 16920916 DOI: 10.4049/Jimmunol.177.5.2810  0.424
2006 Angers I, Sancho-Shimizu V, Descoteaux A, Gewirtz AT, Malo D. Tlr5 is not primarily associated with susceptibility to Salmonella Typhimurium infection in MOLF/Ei mice Mammalian Genome. 17: 385-397. PMID 16688529 DOI: 10.1007/S00335-005-0132-X  0.36
2006 Yu Y, Nagai S, Wu H, Neish AS, Koyasu S, Gewirtz AT. TLR5-mediated phosphoinositide 3-kinase activation negatively regulates flagellin-induced proinflammatory gene expression. Journal of Immunology (Baltimore, Md. : 1950). 176: 6194-201. PMID 16670329 DOI: 10.4049/Jimmunol.176.10.6194  0.38
2006 Lu W, Hisatsune A, Koga T, Kato K, Kuwahara I, Lillehoj EP, Chen W, Cross AS, Gendler SJ, Gewirtz AT, Kim KC. Cutting edge: enhanced pulmonary clearance of Pseudomonas aeruginosa by Muc1 knockout mice. Journal of Immunology (Baltimore, Md. : 1950). 176: 3890-4. PMID 16547220 DOI: 10.4049/Jimmunol.176.7.3890  0.387
2006 Gewirtz AT, Vijay-Kumar M, Brant SR, Duerr RH, Nicolae DL, Cho JH. Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G1157-63. PMID 16439468 DOI: 10.1152/Ajpgi.00544.2005  0.34
2006 Gewirtz AT. Flag in the crossroads: flagellin modulates innate and adaptive immunity. Current Opinion in Gastroenterology. 22: 8-12. PMID 16319670 DOI: 10.1097/01.Mog.0000194791.59337.28  0.403
2006 Zeng H, Wu H, Sloane V, Jones R, Yu Y, Lin P, Gewirtz AT, Neish AS. Flagellin/TLR5 responses in epithelia reveal intertwined activation of inflammatory and apoptotic pathways. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G96-G108. PMID 16179598 DOI: 10.1152/Ajpgi.00273.2005  0.398
2006 Ma-Krupa W, Gršschel S, Piggott K, Vaglio A, Pryshchep O, Shimada K, Gewirtz A, Goronzy JJ, Weyand CM. 254 VASCULAR DENDRITIC CELLS IN GIANT CELL ARTERITIS: TRIGGERING OF VASCULAR INFLAMMATION BY TOLL-LIKE RECEPTOR LIGANDS. Journal of Investigative Medicine. 54: S301.4-S301. DOI: 10.2310/6650.2005.X0008.253  0.326
2005 Castaneda FE, Walia B, Vijay-Kumar M, Patel NR, Roser S, Kolachala VL, Rojas M, Wang L, Oprea G, Garg P, Gewirtz AT, Roman J, Merlin D, Sitaraman SV. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology. 129: 1991-2008. PMID 16344067 DOI: 10.1053/J.Gastro.2005.09.017  0.331
2005 Babbin BA, Gewirtz AT. A most important annexation. The American Journal of Pathology. 166: 1581-3. PMID 15920143 DOI: 10.1016/S0002-9440(10)62468-6  0.331
2005 Vijay-Kumar M, Gentsch JR, Kaiser WJ, Borregaard N, Offermann MK, Neish AS, Gewirtz AT. Protein kinase R mediates intestinal epithelial gene remodeling in response to double-stranded RNA and live rotavirus. Journal of Immunology (Baltimore, Md. : 1950). 174: 6322-31. PMID 15879132 DOI: 10.4049/Jimmunol.174.10.6322  0.392
2005 Sitaraman SV, Klapproth JM, Moore DA, Landers C, Targan S, Williams IR, Gewirtz AT. Elevated flagellin-specific immunoglobulins in Crohn's disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 288: G403-6. PMID 15388489 DOI: 10.1152/Ajpgi.00357.2004  0.352
2005 Walia B, Castaneda FE, Wang L, Kolachala VL, Bajaj R, Roman J, Merlin D, Gewirtz AT, Sitaraman SV. Polarized fibronectin secretion induced by adenosine regulates bacterial-epithelial interaction in human intestinal epithelial cells. The Biochemical Journal. 382: 589-96. PMID 15193149 DOI: 10.1042/Bj20040021  0.366
2004 Lyons S, Wang L, Casanova JE, Sitaraman SV, Merlin D, Gewirtz AT. Salmonella typhimurium transcytoses flagellin via an SPI2-mediated vesicular transport pathway. Journal of Cell Science. 117: 5771-80. PMID 15507487 DOI: 10.1242/Jcs.01500  0.413
2004 Yu Y, Zeng H, Vijay-Kumar M, Neish AS, Merlin D, Sitaraman SV, Gewirtz AT. STAT signaling underlies difference between flagellin-induced and tumor necrosis factor-alpha-induced epithelial gene expression. The Journal of Biological Chemistry. 279: 35210-8. PMID 15199060 DOI: 10.1074/Jbc.M404064200  0.367
2004 Yu Y, Sitaraman S, Gewirtz AT. Intestinal epithelial cell regulation of mucosal inflammation. Immunologic Research. 29: 55-68. PMID 15181270 DOI: 10.1385/Ir:29:1-3:055  0.431
2004 Mrsny RJ, Gewirtz AT, Siccardi D, Savidge T, Hurley BP, Madara JL, McCormick BA. Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia. Proceedings of the National Academy of Sciences of the United States of America. 101: 7421-6. PMID 15123795 DOI: 10.1073/Pnas.0400832101  0.363
2004 Gewirtz AT, Yu Y, Krishna US, Israel DA, Lyons SL, Peek RM. Helicobacter pylori flagellin evades toll-like receptor 5-mediated innate immunity. The Journal of Infectious Diseases. 189: 1914-20. PMID 15122529 DOI: 10.1086/386289  0.353
2004 Lin PW, Simon PO, Gewirtz AT, Neish AS, Ouellette AJ, Madara JL, Lencer WI. Paneth cell cryptdins act in vitro as apical paracrine regulators of the innate inflammatory response. The Journal of Biological Chemistry. 279: 19902-7. PMID 14990585 DOI: 10.1074/Jbc.M311821200  0.394
2004 Sitaraman S, Liu X, Charrier L, Gu LH, Ziegler TR, Gewirtz A, Merlin D. Colonic leptin: source of a novel proinflammatory cytokine involved in IBD. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 696-8. PMID 14977884 DOI: 10.1096/Fj.03-0422Fje  0.388
2004 Lin PW, Simon PO, Gewirtz AT, Neish AS, Ouellette AJ, Madara JL, Lencer WI. 191 PANETH CELL CRYPTDINS ARE APICAL PARACRINE REGULATORS OF THE INNATE INTESTINAL INFLAMMATORY RESPONSE. Journal of Investigative Medicine. 52: S291.3-S291. DOI: 10.1136/Jim-52-Suppl1-744  0.392
2003 Buyse M, Charrier L, Sitaraman S, Gewirtz A, Merlin D. Interferon-gamma increases hPepT1-mediated uptake of di-tripeptides including the bacterial tripeptide fMLP in polarized intestinal epithelia. The American Journal of Pathology. 163: 1969-77. PMID 14578196 DOI: 10.1016/S0002-9440(10)63555-9  0.389
2003 Zeng H, Carlson AQ, Guo Y, Yu Y, Collier-Hyams LS, Madara JL, Gewirtz AT, Neish AS. Flagellin is the major proinflammatory determinant of enteropathogenic Salmonella. Journal of Immunology (Baltimore, Md. : 1950). 171: 3668-74. PMID 14500664 DOI: 10.4049/Jimmunol.171.7.3668  0.4
2003 Wang L, Walia B, Evans J, Gewirtz AT, Merlin D, Sitaraman SV. IL-6 induces NF-kappa B activation in the intestinal epithelia. Journal of Immunology (Baltimore, Md. : 1950). 171: 3194-201. PMID 12960348 DOI: 10.4049/Jimmunol.171.6.3194  0.333
2003 Yu Y, Zeng H, Lyons S, Carlson A, Merlin D, Neish AS, Gewirtz AT. TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G282-90. PMID 12702497 DOI: 10.1016/S0016-5085(03)82441-1  0.369
2003 Langston HP, Ke Y, Gewirtz AT, Dombrowski KE, Kapp JA. Secretion of IL-2 and IFN-gamma, but not IL-4, by antigen-specific T cells requires extracellular ATP. Journal of Immunology (Baltimore, Md. : 1950). 170: 2962-70. PMID 12626548 DOI: 10.4049/Jimmunol.170.6.2962  0.305
2003 Gewirtz AT. Intestinal epithelial toll-like receptors: to protect. And serve? Current Pharmaceutical Design. 9: 1-5. PMID 12570669 DOI: 10.2174/1381612033392422  0.411
2003 Kucharzik T, Gewirtz AT, Merlin D, Madara JL, Williams IR. Lateral membrane LXA4 receptors mediate LXA4's anti-inflammatory actions on intestinal epithelium. American Journal of Physiology. Cell Physiology. 284: C888-96. PMID 12456400 DOI: 10.1152/Ajpcell.00507.2001  0.331
2003 Gewirtz A, Krishna U, Israel D, Yu Y, Peek RM. Helicobacter pylori evades toll-like receptor 5 innate immunity Gastroenterology. 124: A592. DOI: 10.1016/S0016-5085(03)82998-0  0.321
2003 Yu Y, Zeng H, Lyons S, Carlson A, Merlin D, Neish AS, Sitaraman SV, Gewirtz AT. STAT signaling underlies differences between flagellin-induced and TNF-induced epithelial gene expression Gastroenterology. 124: A106. DOI: 10.1016/S0016-5085(03)80523-1  0.347
2002 Gewirtz AT, Neish AS, Madara JL. Mechanisms of active intestinal inflammation and potential down-regulation via lipoxins. Advances in Experimental Medicine and Biology. 507: 229-36. PMID 12664590 DOI: 10.1007/978-1-4615-0193-0_35  0.404
2002 Gewirtz AT, Liu Y, Sitaraman SV, Madara JL. Intestinal epithelial pathobiology: past, present and future. Best Practice & Research. Clinical Gastroenterology. 16: 851-67. PMID 12473295 DOI: 10.1053/Bega.2002.0339  0.383
2002 Renshaw M, Rockwell J, Engleman C, Gewirtz A, Katz J, Sambhara S. Cutting edge: Impaired toll-like receptor expression and function in aging Journal of Immunology. 169: 4697-4701. PMID 12391175 DOI: 10.4049/Jimmunol.169.9.4697  0.377
2002 McSorley SJ, Ehst BD, Yu Y, Gewirtz AT. Bacterial flagellin is an effective adjuvant for CD4+ T cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 169: 3914-9. PMID 12244190 DOI: 10.4049/Jimmunol.169.7.3914  0.345
2002 Gewirtz AT, Collier-Hyams LS, Young AN, Kucharzik T, Guilford WJ, Parkinson JF, Williams IR, Neish AS, Madara JL. Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. Journal of Immunology (Baltimore, Md. : 1950). 168: 5260-7. PMID 11994483 DOI: 10.4049/Jimmunol.168.10.5260  0.418
2002 Gewirtz AT, Reed KA, Merlin D, Hobert M, Neish AS, Madara JL. 21 Modeling microbial-epithelial interactions in the intestine Methods in Microbiology. 31: 377-396. DOI: 10.1016/S0580-9517(02)31022-5  0.326
2001 Gewirtz AT, Navas TA, Lyons S, Godowski PJ, Madara JL. Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression. Journal of Immunology (Baltimore, Md. : 1950). 167: 1882-5. PMID 11489966 DOI: 10.4049/Jimmunol.167.4.1882  0.412
2001 Sitaraman SV, Merlin D, Wang L, Wong M, Gewirtz AT, Si-Tahar M, Madara JL. Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6. The Journal of Clinical Investigation. 107: 861-9. PMID 11285305 DOI: 10.1172/Jci11783  0.347
2001 Gewirtz AT, Madara JL. Periscope, up! Monitoring microbes in the intestine. Nature Immunology. 2: 288-90. PMID 11276197 DOI: 10.1038/86292  0.344
2001 Gewirtz AT, Simon PO, Schmitt CK, Taylor LJ, Hagedorn CH, O'Brien AD, Neish AS, Madara JL. Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response. The Journal of Clinical Investigation. 107: 99-109. PMID 11134185 DOI: 10.1172/Jci10501  0.353
2001 Sitaraman SV, Merlin D, Wang L, Wong M, Gewirtz AT, Si-Tahar M, Madara JL. Adenosine induces polarized secretion of interleukin-6 in intestinal epithelial cells: Bidirectional epithelial/neutrophil paracrine regulation in model crypt abscess Gastroenterology. 120: A184-A185. DOI: 10.1016/S0016-5085(08)80913-4  0.354
2000 Neish AS, Gewirtz AT, Zeng H, Young AN, Hobert ME, Karmali V, Rao AS, Madara JL. Prokaryotic regulation of epithelial responses by inhibition of IkappaB-alpha ubiquitination. Science (New York, N.Y.). 289: 1560-3. PMID 10968793 DOI: 10.1126/Science.289.5484.1560  0.342
2000 Gewirtz AT, Rao AS, Simon PO, Merlin D, Carnes D, Madara JL, Neish AS. Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-kappaB pathway. The Journal of Clinical Investigation. 105: 79-92. PMID 10619864 DOI: 10.1172/Jci8066  0.359
2000 Gewirtz AT, Simon PO, Esterly D, Neish AS, Madara JL. S. typhimurium secretes a novel pro-inflammatory factor that is translocated across model intestinal epithelia Gastroenterology. 118: A101. DOI: 10.1016/S0016-5085(00)82482-8  0.306
1999 Gewirtz AT, Fokin VV, Petasis NA, Serhan CN, Madara JL. LXA4, aspirin-triggered 15-epi-LXA4, and their analogs selectively downregulate PMN azurophilic degranulation. The American Journal of Physiology. 276: C988-94. PMID 10199831 DOI: 10.1152/Ajpcell.1999.276.4.C988  0.353
1999 Gewirtz AT, Siber AM, Madara JL, McCormick BA. Orchestration of neutrophil movement by intestinal epithelial cells in response to Salmonella typhimurium can be uncoupled from bacterial internalization. Infection and Immunity. 67: 608-17. PMID 9916066 DOI: 10.1128/Iai.67.2.608-617.1999  0.383
1998 Gewirtz AT, Seetoo KF, Simons ER. Neutrophil degranulation and phospholipase D activation are enhanced if the Na+/H+ antiport is blocked. Journal of Leukocyte Biology. 64: 98-103. PMID 9665282 DOI: 10.1002/Jlb.64.1.98  0.308
1998 Gewirtz AT, McCormick B, Neish AS, Petasis NA, Gronert K, Serhan CN, Madara JL. Pathogen-induced chemokine secretion from model intestinal epithelium is inhibited by lipoxin A4 analogs. The Journal of Clinical Investigation. 101: 1860-9. PMID 9576749 DOI: 10.1172/Jci1339  0.42
1998 McCormick B, Gewirtz A, Madara JL. Epithelial crosstalk with bacteria and immune cells Current Opinion in Gastroenterology. 14: 492-497. DOI: 10.1097/00001574-199811000-00013  0.358
Low-probability matches (unlikely to be authored by this person)
2010 Anitha M, Vijay-Kumar M, Sitaraman SV, Gewirtz AT, Srinivasan S. 10 Altered Gastrointestinal Motility and Reduced nNOS Neurons in TLR4 Mutant-Mice Gastroenterology. 138: S-1. DOI: 10.1016/S0016-5085(10)60004-2  0.3
2015 Yang B, Bostick RM, Gewirtz AT, Tran HQ, Fedirko V. Abstract 938: Circulating biomarkers of gut barrier function: Correlates and responses to calcium supplementation among sporadic colorectal adenoma patients in a dose-response randomized controlled trial Cancer Research. 75: 938-938. DOI: 10.1158/1538-7445.Am2015-938  0.3
2020 Yang T, Chakraborty S, Saha P, Mell B, Cheng X, Yeo JY, Mei X, Zhou G, Mandal J, Golonka R, Yeoh BS, Putluri V, Piyarathna DWB, Putluri N, McCarthy CG, ... ... Gewirtz A, et al. Gnotobiotic Rats Reveal that Gut Microbiota Regulates Colonic mRNA of , the Receptor for SARS-CoV-2 Infectivity. Hypertension (Dallas, Tex. : 1979). PMID 32426999 DOI: 10.1161/Hypertensionaha.120.15360  0.3
1998 Gewirtz A, McCormick B, Neish A, Petasis N, Gronert K, Serhan C, Madara J. Release of pro-inflammatory chemokines from model intestinal epithelia is inhibited by lipoxin A4 analogs Gastroenterology. 114: A372. DOI: 10.1016/S0016-5085(98)81509-6  0.3
1998 Merlin D, Steel A, Gewirtz AT, Si-Tahar M, Hediger MA, Madara JL. hPepT1-mediated epithelial transport of bacteria-derived chemotactic peptides enhances neutrophil-epithelial interactions. The Journal of Clinical Investigation. 102: 2011-8. PMID 9835627 DOI: 10.1172/Jci4179  0.299
2016 Lee YN, Lee YT, Kim MC, Gewirtz AT, Kang SM. A Novel Vaccination Strategy Mediating the Induction of Lung-Resident Memory CD8 T Cells Confers Heterosubtypic Immunity against Future Pandemic Influenza Virus. Journal of Immunology (Baltimore, Md. : 1950). PMID 26864033 DOI: 10.4049/Jimmunol.1501637  0.298
2015 Yang B, Bostick RM, Tran HQ, Gewirtz AT, Campbell PT, Fedirko V. Circulating biomarkers of gut barrier function: Correlates and non-response to calcium supplementation among colon adenoma patients. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26677212 DOI: 10.1158/1055-9965.Epi-15-0488  0.298
2003 Klapproth J, Moore DA, Sitaraman SV, Gewirtz AT. Enhanced adaptive immune response to E. coli flagellin in IBD Gastroenterology. 124: A112. DOI: 10.1016/S0016-5085(03)80551-6  0.297
2020 Wang Y, Zou J, Bretin A, Allan D, Carlyle JR, Gewirtz AT. Tu1259 INDUCTION OF INNATE LYMPHOID CELL IL-22 IN AN EX VIVO MODEL VIA A MICROBIOTA-PRODUCED TRYPSIN-RESISTANT PROTEIN Gastroenterology. 158: S-1035. DOI: 10.1016/S0016-5085(20)33269-8  0.297
2012 Tehrani AB, Nezami BG, Gewirtz AT, Srinivasan S. Obesity and its associated disease: a role for microbiota? Neurogastroenterology and Motility. 24: 305-311. PMID 22339979 DOI: 10.1111/J.1365-2982.2012.01895.X  0.295
2014 Chassaing B, Gewirtz AT. Pathobiont hypnotises enterocytes to promote tumour development. Gut. 63: 1837-8. PMID 24780742 DOI: 10.1136/Gutjnl-2014-306890  0.294
2019 Shi Z, Zou J, Zhang Z, Zhao X, Noriega J, Zhang B, Zhao C, Ingle H, Bittinger K, Mattei LM, Pruijssers AJ, Plemper RK, Nice TJ, Baldridge MT, Dermody TS, ... ... Gewirtz AT, et al. Segmented Filamentous Bacteria Prevent and Cure Rotavirus Infection. Cell. PMID 31607511 DOI: 10.1016/J.Cell.2019.09.028  0.294
2015 Reichardt F, Tabatabavakili S, Nezami BG, Chassaing B, Mandalia AB, Gewirtz AT, Jones D, Srinivasan S. 74 Fecal Metabolites Associated With Nitrergic Myenteric Neuronal Impairment and Gastrointestinal Motility Disorders in Western Diet-Fed Mice Gastroenterology. 148: S-21. DOI: 10.1016/S0016-5085(15)30074-3  0.294
2011 Vijay-Kumar M, Aitken JD, Su Y, Srinivasan G, Carvalho FA, Gewirtz AT. Gnotobiotic Toll-Like Receptor 5 Deficient Mice Lack Spontaneous Colitis and Metabolic Syndrome Gastroenterology. 140: S-324. DOI: 10.1016/S0016-5085(11)61314-0  0.294
2018 Ngo VL, Abo H, Maxim E, Harusato A, Geem D, Medina-Contreras O, Merlin D, Gewirtz AT, Nusrat A, Denning TL. A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage. Proceedings of the National Academy of Sciences of the United States of America. PMID 29760082 DOI: 10.1073/Pnas.1718902115  0.294
2020 Sandall AM, Cox SR, Lindsay JO, Gewirtz AT, Chassaing B, Rossi M, Whelan K. Emulsifiers Impact Colonic Length in Mice and Emulsifier Restriction is Feasible in People with Crohn's Disease. Nutrients. 12. PMID 32942699 DOI: 10.3390/Nu12092827  0.293
2012 Carvalho F, Meleine M, Vijay-Kumar M, Gewirtz A, Eschalier A, Ardid D. Defect in TLR5 Expression Enhances Spontaneous Visceral Hypersensitivity Inflammatory Bowel Diseases. 18: S108. DOI: 10.1097/00054725-201212001-00276  0.292
2002 Reed KA, Hobert ME, Kolenda CE, Sands KA, Rathman M, O'Connor M, Lyons S, Gewirtz AT, Sansonetti PJ, Madara JL. The Salmonella typhimurium flagellar basal body protein FliE is required for flagellin production and to induce a proinflammatory response in epithelial cells. The Journal of Biological Chemistry. 277: 13346-53. PMID 11821427 DOI: 10.1074/jbc.M200149200  0.292
2017 Zou J, Chassaing B, Gewirtz AT. Dietary Fiber Protect Against High-Fat Diet-Induced Metabolic Syndrome Through Myd88-Mediated IL-22 Production that Reduces Microbiota Encroachment Gastroenterology. 152: S1013. DOI: 10.1016/S0016-5085(17)33437-6  0.292
2009 Hossain M, Roback J, Gewirtz A, Waller E. Flagellin, A TLR5 Agonist, Facilitates Production of foxp3+CD4+CD25+ Regulatory T Cells to Maintain Balanced Immune Reconstitution in Allogeneic BMT without GvHD Biology of Blood and Marrow Transplantation. 15: 12. DOI: 10.1016/J.Bbmt.2008.12.035  0.291
2014 Anitha M, Nezami BG, Mwangi SM, Chassaing B, Vijay-Kumar M, Gewirtz AT, Srinivasan S. 26 Intestinal Dysbiosis Contributes to the Delayed Gastrointestinal Transit in High Fat Diet Fed Mice Gastroenterology. 146: S-8. DOI: 10.1016/S0016-5085(14)60026-3  0.291
1999 Gronert K, Gewirtz A, Madara JL, Serhan CN. Identification of a human enterocyte lipoxin a receptor that is regulated by IL-13 and IFN-γ and inhibits TNF-α-induced IL-8 release Prostaglandins & Other Lipid Mediators. 59: 187. DOI: 10.1016/S0090-6980(99)90422-7  0.289
2014 Galloway D, Troutt M, Cohen MB, Kocoshis SA, Gewirtz AT, Ziegler TR, Cole CR. Tu1266 Increased Anti-Flagellin-and Anti-Lipopolysaccharide Immunogloblulins in Pediatric Intestinal Failure: Associations With Fever and Central Line-Associated Blood-Stream Infections Gastroenterology. 146. DOI: 10.1016/S0016-5085(14)62885-7  0.288
2011 Garg P, Jeppsson S, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. MMP-9 mediates colitis associated cancer in mice through Notch-1 via p53 activation Inflammatory Bowel Diseases. 17: S9. DOI: 10.1097/00054725-201112002-00023  0.287
2008 Chandrasekharan B, Bala V, Kolachala VL, Vijay-Kumar M, Jones D, Gewirtz AT, Sitaraman SV, Srinivasan S. Targeted deletion of neuropeptide Y (NPY) modulates experimental colitis. Plos One. 3: e3304. PMID 18836554 DOI: 10.1371/Journal.Pone.0003304  0.287
2008 Hossain M, Gewirtz AT, Roback JD, Waller EK. Flagellin, a TLR5 Agonist, Down-Regulate CD62L on Donor T Cells and Limit GvHD in Allogeneic Hematopoietic Stem Cell Transplantation Blood. 112: 3521-3521. DOI: 10.1182/Blood.V112.11.3521.3521  0.286
2000 Neish AS, Gewirtz AT, Rao AS, Madara JL. Non-pathogenic bacteria may block epithelial responses: Attenuation of IKB-A ubiquitination as a novel, physiologic mode of antiinflammation Gastroenterology. 118: A683. DOI: 10.1016/S0016-5085(00)84866-0  0.286
2019 Tran H, Bretin A, Adeshirlarijaney A, San Yeoh B, Vijay-Kumar M, Zou J, Denning TL, Chassaing B, Gewirtz AT. "Western-diet"-induced adipose inflammation requires a complex gut microbiota. Cellular and Molecular Gastroenterology and Hepatology. PMID 31593782 DOI: 10.1016/j.jcmgh.2019.09.009  0.284
2016 Harusato A, Medina-Contreras O, Nishio H, Chassaing B, Gewirtz A, Parkos C, Towne J, Nusrat A, Denning T. P-146 IL-36 Receptor Is Required for Resolution of Intestinal Damage Inflammatory Bowel Diseases. 22: S54-S55. DOI: 10.1097/01.Mib.0000480273.37247.26  0.284
2016 Chassaing B, Koren O, Goodrich JK, Poole AC, Srinivasan S, Ley RE, Gewirtz AT. Corrigendum: Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome. Nature. PMID 27144359 DOI: 10.1038/Nature18000  0.283
2008 Anitha M, Miller AB, Chandrasekharan BP, Mwangi S, Vijay-Kumar M, Sitaraman SV, Gewirtz AT, Srinivasan S. W1341 Hyperglycemia-Induced Enteric Neuronal Apoptosis Is Mediated Through Enhanced Oxidative Stress and TLR4 Signaling Gastroenterology. 134: A-684. DOI: 10.1016/S0016-5085(08)63191-1  0.281
2014 Etienne-Mesmin L, Chassaing B, Edwards AN, Miles JP, McBride S, Gewirtz AT. Sa1289 Culture-Independent Quantitation of Clostridium difficile in C57BL/6 Mice Aids Mechanistic Study of Disease Pathophysiology and Protective Immunology Gastroenterology. 146: S-253. DOI: 10.1016/S0016-5085(14)60891-X  0.281
2008 Cole CR, Frem JC, Gewirtz AT, Gold BD, Ziegler TR. M1713 The Relationship Between Bacterial Overgrowth, Intestinal Permeability and TNF Alpha in Pediatric Short Bowel Syndrome Gastroenterology. 134: A-403. DOI: 10.1016/S0016-5085(08)61883-1  0.281
2016 Geem D, Ngo V, Harusato A, Chassaing B, Gewirtz AT, Newberry RD, Denning TL. Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell Compartment. Cellular and Molecular Gastroenterology and Hepatology. 2: 274-280. PMID 27570813 DOI: 10.1016/J.Jcmgh.2015.12.009  0.28
2012 Anitha M, Vijay-Kumar M, Gewirtz AT, Srinivasan S. Tu1973 Gut Microbiota Regulate Murine Gastrointestinal Motility Through a Toll-Like Receptor 4 Dependent Pathway Gastroenterology. 142: S-890. DOI: 10.1016/S0016-5085(12)63460-X  0.28
2023 Vijay-Kumar M, Bovilla VR, Yeoh BS, Golonka RM, Saha P, Joe B, Gewirtz AT. Bacterial flagellin is a dominant, stable innate immune activator in the gastrointestinal contents of mice and rats. Gut Microbes. 15: 2185031. PMID 36880647 DOI: 10.1080/19490976.2023.2185031  0.28
2020 Chassaing B, Gershuni V, McKeever L, Compher C, Bonhomme B, Harb AH, Nessel L, Wu GD, Gewirtz AT, Lewis JD. 1008 A RANDOMIZED CONTROLLED-FEEDING STUDY OF THE IMPACT OF THE SYNTHETIC DIETARY EMULSIFIER CARBOXYMETHYLCELLULOSE ON HUMAN HEALTH AND INTESTINAL MICROBIOTA Gastroenterology. 158: S-200. DOI: 10.1016/S0016-5085(20)31184-7  0.278
2017 Etienne-Mesmin L, Chassaing B, Adekunle O, Mattei LM, Bushman FD, Gewirtz AT. Toxin-positive Clostridium difficile latently infect mouse colonies and protect against highly pathogenic C. difficile. Gut. PMID 28219893 DOI: 10.1136/Gutjnl-2016-313510  0.277
2012 Vijay-Kumar M, Gewirtz AT. Is predisposition to NAFLD and obesity communicable? Cell Metabolism. 15: 419-20. PMID 22482724 DOI: 10.1016/J.Cmet.2012.03.013  0.277
2011 Prasad MA, Wang L, Garg P, Yang SC, Gewirtz AT, Merlin D, Sitaraman SV. Tumor Necrosis Factor-α (TNF-α) Induced Colonic Epithelial Matrix Metalloproteinase-9 (MMP-9) Expression is Regulated by Early Growth Response Factor (EGR-1) Gastroenterology. 140: S-632. DOI: 10.1016/S0016-5085(11)62613-9  0.276
2008 Kolachala VL, Vijay-Kumar M, Wang L, Yang D, Marshall M, Wang G, Linden J, Gewirtz AT, Merlin D, Ravid K, Sitaraman SV. S1296 A2b Adenosine Receptor Gene Deletion or Antagonism Attenuates Murine Colitis Gastroenterology. 134: A-220. DOI: 10.1016/S0016-5085(08)61018-5  0.275
2014 Johansson ME, Gustafsson JK, Holmén-Larsson J, Jabbar KS, Xia L, Xu H, Ghishan FK, Carvalho FA, Gewirtz AT, Sjövall H, Hansson GC. Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis. Gut. 63: 281-91. PMID 23426893 DOI: 10.1136/Gutjnl-2012-303207  0.275
2009 Hossain MS, Gewirtz AT, Roback JD, Waller EK. Prophylactic Use of Flagellin: A Novel Method to Boost Immune Reconstitution in Allogeneic HSCT Recipients with Limited GvHD. Blood. 114: 3561-3561. DOI: 10.1182/Blood.V114.22.3561.3561  0.274
2018 Fulde M, Sommer F, Chassaing B, van Vorst K, Dupont A, Hensel M, Basic M, Klopfleisch R, Rosenstiel P, Bleich A, Bäckhed F, Gewirtz AT, Hornef MW. Publisher Correction: Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition. Nature. PMID 30158704 DOI: 10.1038/S41586-018-0507-2  0.274
2022 Mallaret G, Lashermes A, Meleine M, Boudieu L, Barbier J, Aissouni Y, Gelot A, Chassaing B, Gewirtz AT, Ardid D, Carvalho FA. Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation. World Journal of Gastroenterology. 28: 3903-3916. PMID 36157543 DOI: 10.3748/wjg.v28.i29.3903  0.273
2011 Carvalho FA, Aitken JD, Vijay-Kumar M, Gewirtz AT. IL-1β Promotes Susceptibility of TLR5KO Mice to Colitis Gastroenterology. 140: S-697. DOI: 10.1016/S0016-5085(11)62892-8  0.272
2010 Hossain MS, Gewirtz AT, Roback J, Waller E. Paradoxical Immunological Activity of Flagellin: A Novel Method to Reduce GvHD In Allogeneic HSCT Recipients. Blood. 116: 1465-1465. DOI: 10.1182/Blood.V116.21.1465.1465  0.271
2003 Charrier L, Liu X, Gewirtz A, Sitaraman S, Merlin D. CD98 binds to neutrophil membrane and increases the activity of the amino acid transporter (LAT-2) in the human intestinal cell line Caco2-BBE Gastroenterology. 124: A309. DOI: 10.1016/S0016-5085(03)81558-5  0.269
2017 Fedirko V, Tran HQ, Gewirtz AT, Stepien M, Trichopoulou A, Aleksandrova K, Olsen A, Tjønneland A, Overvad K, Carbonnel F, Boutron-Ruault MC, Severi G, Kühn T, Kaaks R, Boeing H, et al. Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma: a nested case-control study. Bmc Medicine. 15: 72. PMID 28372583 DOI: 10.1186/S12916-017-0830-8  0.268
2008 Kolachala VL, Vijay-Kumar M, Dalmasso G, Yang D, Linden J, Wang L, Gewirtz A, Ravid K, Merlin D, Sitaraman SV. A2B adenosine receptor gene deletion attenuates murine colitis. Gastroenterology. 135: 861-70. PMID 18601927 DOI: 10.1053/J.Gastro.2008.05.049  0.268
2021 An J, Zhao X, Wang Y, Noriega J, Gewirtz AT, Zou J. Western-style diet impedes colonization and clearance of Citrobacter rodentium. Plos Pathogens. 17: e1009497. PMID 33819308 DOI: 10.1371/journal.ppat.1009497  0.266
2010 Kolachala VL, Wang L, Obertone TS, Prasad M, Yan Y, Dalmasso G, Gewirtz AT, Merlin D, Sitaraman SV. Adenosine 2B receptor expression is post-transcriptionally regulated by microRNA. The Journal of Biological Chemistry. 285: 18184-90. PMID 20388705 DOI: 10.1074/Jbc.M109.066555  0.265
2019 Bretin A, Zou J, Chassaing B, Gewirtz AT. 1014 – Seeking Dietary Fibers to Ameliorate Inflammatory Bowel Disease and Metabolic Syndrome Gastroenterology. 156: S-220. DOI: 10.1016/S0016-5085(19)37346-9  0.265
2019 Iqbal NT, Syed S, Kabir F, Jamil Z, Akhund T, Qureshi S, Liu J, Ma JZ, Guleria S, Gewirtz A, Duggan CP, Hughes MA, Sadiq K, Ali A. Pathobiome driven gut inflammation in Pakistani children with Environmental Enteric Dysfunction. Plos One. 14: e0221095. PMID 31442248 DOI: 10.1371/Journal.Pone.0221095  0.264
2012 Chassaing B, Srinivasan G, Young A, Delgado M, Gewirtz A, Vijay-Kumar M. Fecal Lipocalin 2, a Sensitive and Broadly Dynamic Non-Invasive Biomarker of Gut Inflammation Inflammatory Bowel Diseases. 18: S108. DOI: 10.1097/00054725-201212001-00277  0.263
2018 Singh V, Yeoh BS, Chassaing B, Xiao X, Saha P, Aguilera Olvera R, Lapek JD, Zhang L, Wang WB, Hao S, Flythe MD, Gonzalez DJ, Cani PD, Conejo-Garcia JR, Xiong N, ... ... Gewirtz AT, et al. Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer. Cell. 175: 679-694.e22. PMID 30340040 DOI: 10.1016/J.Cell.2018.09.004  0.263
2017 Miles JP, Zou J, Kumar MV, Pellizzon M, Ulman E, Ricci M, Gewirtz AT, Chassaing B. Supplementation of Low- and High-fat Diets with Fermentable Fiber Exacerbates Severity of DSS-induced Acute Colitis. Inflammatory Bowel Diseases. PMID 28590342 DOI: 10.1097/Mib.0000000000001155  0.261
2010 Aitken JD, Carvalho FA, Sitaraman SV, Gewirtz AT, Vijay-Kumar M. S1731 High Fat Diet Drives Immunological Changes in the Gut That Predispose to Development of Experimental Colitis Gastroenterology. 138: S-262. DOI: 10.1016/S0016-5085(10)61201-2  0.261
2017 Fields CT, Chassaing B, Paul MJ, Gewirtz AT, de Vries GJ. Vasopressin deletion is associated with sex-specific shifts in the gut microbiome. Gut Microbes. 0. PMID 28759308 DOI: 10.1080/19490976.2017.1356557  0.26
2009 Garg P, Vijay-Kumar M, Wang L, Gewirtz AT, Merlin D, Sitaraman SV. Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G175-84. PMID 19171847 DOI: 10.1152/Ajpgi.90454.2008  0.259
2016 Kong SY, Tran HQ, Gewirtz AT, McKeown-Eyssen G, Fedirko V, Romieu I, Tjønneland A, Olsen A, Overvad K, Boutron-Ruault MC, Bastide N, Affret A, Kühn T, Kaaks R, Boeing H, et al. Serum Endotoxins and Flagellin and Risk of Colorectal Cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) Cohort. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 26823475 DOI: 10.1158/1055-9965.Epi-15-0798  0.259
2020 Mallaret G, Lashermes A, Hamieh AM, Meleine M, Barbier J, Aissouni Y, Ardid D, Gewirtz AT, Chassaing B, Marchand F, Carvalho FA. Mo1342 ROLE OF TOLL-LIKE RECEPTOR 5 IN THE BRAIN-GUT-MICROBIOTA TRIALOGUE: A NEW PHARMACOLOGICAL TARGET FOR THE TREATMENT OF CHRONIC ABDOMINAL PAIN AND ASSOCIATED COMORBIDITIES Gastroenterology. 158: S-857. DOI: 10.1016/S0016-5085(20)32819-5  0.258
2016 McDonald CM, Manji KP, Gosselin K, Tran H, Liu E, Kisenge R, Aboud S, Fawzi WW, Gewirtz AT, Duggan CP. Elevations in serum anti-flagellin and anti-LPS Igs are related to growth faltering in young Tanzanian children. The American Journal of Clinical Nutrition. PMID 27121948 DOI: 10.3945/Ajcn.116.131409  0.258
2009 Anitha M, Mwangi S, Chandrasekharan BP, Vijay-Kumar M, Sitaraman SV, Gewirtz AT, Srinivasan S. S1269 TLR4 Signaling Plays An Important Role in Hyperglycemia-Induced Enteric Neuronal Apoptosis and Colonic Dysmotility Gastroenterology. 136: A-226. DOI: 10.1016/S0016-5085(09)61018-0  0.258
2003 Liu X, Charrier L, Gewirtz A, Sitaraman S, Merlin D. CD98 and intracellular adhesion molecule I regulate the activity of amino acid transporter LAT-2 in polarized intestinal epithelia. The Journal of Biological Chemistry. 278: 23672-7. PMID 12716892 DOI: 10.1074/Jbc.M302777200  0.258
2015 Etienne-Mesmin L, Wang T, Viennois E, Chassaing B, Gewirtz AT, Merlin D. Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium. Inflammatory Bowel Diseases. 21: 1942-7. PMID 26389819 DOI: 10.1097/Mib.0000000000000528  0.257
2016 Etienne-Mesmin L, Chassaing B, Adekunle O, Edwards AN, McBride SM, Gewirtz AT. Mo1673 Discovery of a Toxin-Positive Non-Pathogenic Clostridium difficile Isolate That Protects Against Pathogenic C. difficile Gastroenterology. 150: S749. DOI: 10.1016/S0016-5085(16)32543-4  0.257
2017 Harusato A, Abo H, Ngo V, Yi S, Osuka S, Kohlmeier J, Li JD, Gewirtz A, Nusrat A, Denning T. O-012 IL-36 Signaling Controls the Induced Regulatory T Cell-TH9 Cell Balance and Gut Inflammation. Inflammatory Bowel Diseases. 23: S4-S5. PMID 28125560 DOI: 10.1097/01.MIB.0000512522.22328.4a  0.257
2018 Bretin A, Gewirtz AT, Chassaing B. Microbiota and Metabolism -- What's New in 2018. American Journal of Physiology. Endocrinology and Metabolism. PMID 29486139 DOI: 10.1152/Ajpendo.00014.2018  0.257
2016 Gosselin KB, Aboud S, McDonald CM, Moyo S, Khavari N, Manji K, Kisenge R, Fawzi W, Kellogg M, Tran HQ, Kibiki G, Gratz J, Liu J, Gewirtz A, Houpt E, et al. Etiology of Diarrhea, Nutritional Outcomes and Novel Intestinal Biomarkers in Tanzanian Infants: A Preliminary Study. Journal of Pediatric Gastroenterology and Nutrition. PMID 27347720 DOI: 10.1097/Mpg.0000000000001323  0.256
2017 Kanhere M, He J, Chassaing B, Ziegler TR, Alvarez JA, Ivie EA, Hao L, Hanfelt J, Gewirtz AT, Tangpricha V. Bolus weekly vitamin D3 supplementation impacts gut and airway microbiota in adults with cystic fibrosis: a double-blind, randomized, placebo-controlled clinical trial. The Journal of Clinical Endocrinology and Metabolism. PMID 29161417 DOI: 10.1210/Jc.2017-01983  0.253
2011 Garg P, Jeppsson S, Dalmasso G, Ghaleb A, Patel NR, McConnell BB, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. MMP-9 Modulates Colitis Associated Cancer Through Notch-1-Mediated p53 Activation Gastroenterology. 140: S-181-S-182. DOI: 10.1016/S0016-5085(11)60733-6  0.252
2009 Kolachala VL, Wang L, Yan Y, Obertone TS, Gewirtz AT, Merlin D, Sitaraman SV. S1767 TNF-α-Induced Adenosine 2B Receptor Expression Is Post-Transcriptionally Regulated By miRNA 27b and miRNA128a Gastroenterology. 136: A-266. DOI: 10.1016/S0016-5085(09)61210-5  0.252
1998 Shibahara T, Shaw S, Hermanowski-Vosatka A, Gewirtz A, McCormick B, Nusrat A, Parkos C, Madara J. Efficient homing of intraepithelial-derived lymphocytes (IEL) back to the intercellular spaces of model-polarized intestinal epithelia Gastroenterology. 114: A1083. DOI: 10.1016/S0016-5085(98)84407-7  0.252
2017 Etienne-Mesmin L, Chassaing B, Adekunle O, Mattei LM, Bushman FD, Gewirtz AT. Toxin-Positive Clostridium Difficile Strain Lem1 Latently Infect Mouse Colonies and Protects Against Highlypathogenic C. Difficile Gastroenterology. 152: S48. DOI: 10.1016/S0016-5085(17)30521-8  0.251
2018 Partrick KA, Chassaing B, Beach LQ, McCann KE, Gewirtz AT, Huhman KL. Corrigendum to "Acute and repeated exposure to social stress reduces gut microbiota diversity in Syrian hamsters" [Behav. Brain Res. 345 (2018) 39-48]. Behavioural Brain Research. PMID 29673868 DOI: 10.1016/J.Bbr.2018.03.044  0.25
2015 Miles-Brown JP, Chassaing B, Gewirtz AT. Su1879 Microbiota Metabolism of Soluble Fiber Protects Against Low-Grade Inflammation and Metabolic Syndrome Gastroenterology. 148: S-541. DOI: 10.1016/S0016-5085(15)31815-1  0.249
1999 Mazzucchelli L, Burritt JB, Jesaitis AJ, Nusrat A, Liang TW, Gewirtz AT, Schnell FJ, Parkos CA. Cell-specific peptide binding by human neutrophils. Blood. 93: 1738-1748. DOI: 10.1182/Blood.V93.5.1738  0.249
2007 Charrier L, Yan Y, Nguyen HTT, Dalmasso G, Laboisse CL, Gewirtz AT, Sitaraman SV, Merlin D. Both the RGD sequence and the cytoplasmic tail of ADAM15 are required for homotypic aggregation of T lymphocytes and heterotypic interactions between T lymphocytes and intestinal epithelia. The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A586-B  0.246
2006 Ma-Krupa W, Groschel S, Piggott K, Vaglio A, Pryshchep O, Shimada K, Gewirtz A, Goronzy J, Weyand C. OR.53. Vascular Dendritic Cells Regulate Tissue Invasiveness of CD4 T-Cells Clinical Immunology. 119: S23-S24. DOI: 10.1016/J.Clim.2006.04.209  0.246
2019 Yang B, Petrick JL, Thistle JE, Pinto L, Kemp TJ, Tran HQ, Gewirtz AT, Waterboer T, Fedirko V, Jenab M, Graubard BI, Weinstein SJ, Albanes D, McGlynn KA. Bacterial translocation and risk of liver cancer in a Finnish cohort. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 30602499 DOI: 10.1158/1055-9965.Epi-18-0240  0.244
2015 Viennois E, Chassaing B, Zhao Y, Wang L, Xiao B, Gewirtz AT, Merlin D. Mo1780 Fecal miRNAs: An Indicator of Intestinal Microbiota Healthiness Gastroenterology. 148: S-709-S-710. DOI: 10.1016/S0016-5085(15)32410-0  0.243
2019 Lauer JM, McDonald CM, Kisenge R, Aboud S, Fawzi WW, Liu E, Tran HQ, Gewirtz AT, Manji KP, Duggan CP. Markers of Systemic Inflammation and Environmental Enteric Dysfunction Are Not Reduced by Zinc or Multivitamins in Tanzanian Infants: A Randomized, Placebo-Controlled Trial. The Journal of Pediatrics. PMID 30952509 DOI: 10.1016/J.Jpeds.2019.02.016  0.236
2008 Garg P, Vijay-Kumar M, Wang L, Ravi A, Gewirtz AT, Merlin D, Sitaraman SV. S1292 MMP9 Mediated Tissue Injury Overrides the Protective Effect of MMP2 On the Development of Colitis Gastroenterology. 134: A-219. DOI: 10.1016/S0016-5085(08)61014-8  0.235
2000 Gewirtz AT, Madara JL. Lipoxin-stable analogs: potential therapeutic downregulators of intestinal inflammation. Ernst Schering Research Foundation Workshop. 187-99. PMID 10943333 DOI: 10.1007/978-3-662-04047-8_9  0.235
2021 Naimi S, Viennois E, Gewirtz AT, Chassaing B. Direct impact of commonly used dietary emulsifiers on human gut microbiota. Microbiome. 9: 66. PMID 33752754 DOI: 10.1186/s40168-020-00996-6  0.234
2023 Bretin A, Yeoh BS, Ngo VL, Reddivari L, Pellizzon M, Vijay-Kumar M, Gewirtz AT. Psyllium fiber protects mice against western diet-induced metabolic syndrome via the gut microbiota-dependent mechanism. Gut Microbes. 15: 2221095. PMID 37305942 DOI: 10.1080/19490976.2023.2221095  0.233
2023 Clasen SJ, Bell MEW, Borbón A, Lee DH, Henseler ZM, de la Cuesta-Zuluaga J, Parys K, Zou J, Wang Y, Altmannova V, Youngblut ND, Weir JR, Gewirtz AT, Belkhadir Y, Ley RE. Silent recognition of flagellins from human gut commensal bacteria by Toll-like receptor 5. Science Immunology. 8: eabq7001. PMID 36608151 DOI: 10.1126/sciimmunol.abq7001  0.229
2022 Mills RH, Dulai PS, Vázquez-Baeza Y, Sauceda C, Daniel N, Gerner RR, Batachari LE, Malfavon M, Zhu Q, Weldon K, Humphrey G, Carrillo-Terrazas M, Goldasich LD, Bryant M, Raffatellu M, ... ... Gewirtz AT, et al. Multi-omics analyses of the ulcerative colitis gut microbiome link Bacteroides vulgatus proteases with disease severity. Nature Microbiology. PMID 35087228 DOI: 10.1038/s41564-021-01050-3  0.229
2018 Partrick KA, Chassaing B, Beach LQ, McCann KE, Gewirtz AT, Huhman KL. Acute and repeated exposure to social stress reduces gut microbiota diversity in Syrian hamsters. Behavioural Brain Research. PMID 29474810 DOI: 10.1016/J.Bbr.2018.02.005  0.229
2018 Etheredge AJ, Manji K, Kellogg M, Tran H, Liu E, McDonald CM, Kisenge R, Aboud S, Fawzi W, Bellinger D, Gewirtz AT, Duggan CP. Markers of Environmental Enteric Dysfunction Are Associated With Neurodevelopmental Outcomes in Tanzanian Children. Journal of Pediatric Gastroenterology and Nutrition. PMID 29613921 DOI: 10.1097/Mpg.0000000000001978  0.229
2010 Garg P, Bialkowska A, Jeppsson S, Yang VW, Gewirtz AT, Merlin D, Sitaraman SV. M1935 MMP-9 Functions as a Tumor Suppressor in Colitis-Associated Cancer Through Its Effects on Cell Cycle Gastroenterology. 138: S-442-S-443. DOI: 10.1016/S0016-5085(10)62046-X  0.228
2014 Aitken J, Miles JP, Vijay-Kumar M, Ulman E, Pellizzon M, Chassaing B, Ricci M, Gewirtz AT. Tu2031 Lack of soluble fiber drives ‘High-fat diet’-induced metabolic syndrome Gastroenterology. 146: S-901. DOI: 10.1016/S0016-5085(14)63278-9  0.228
2018 Syed S, Iqbal NT, Sadiq K, Ma JZ, Akhund T, Xin W, Moore SR, Liu E, Qureshi S, Gosselin K, Gewirtz A, Duggan CP, Ali SA. Serum anti-flagellin and anti-lipopolysaccharide immunoglobulins as predictors of linear growth faltering in Pakistani infants at risk for environmental enteric dysfunction. Plos One. 13: e0193768. PMID 29509790 DOI: 10.1371/Journal.Pone.0193768  0.227
2017 Tran HQ, Holder MK, Chassaing B, Gewirtz AT. Predictors and Correlates of Proneness to Diet-Induced Obesity Gastroenterology. 152: S829. DOI: 10.1016/S0016-5085(17)32863-9  0.225
2013 Anitha M, Nezami BG, Vijay-Kumar M, Gewirtz AT, Srinivasan S. Su2046 Delayed Gastrointestinal Transit in OB/OB Mice Correlates With Reduced Intestinal TLR4 Signaling and Loss of Nitrergic Neurons Gastroenterology. 144: S-541. DOI: 10.1016/S0016-5085(13)62008-9  0.223
1997 Gewirtz AT, Simons ER. Phospholipase D mediates Fc gamma receptor activation of neutrophils and provides specificity between high-valency immune complexes and fMLP signaling pathways. Journal of Leukocyte Biology. 61: 522-8. PMID 9103240 DOI: 10.1002/jlb.61.4.522  0.222
2018 Golonka RM, Yeoh BS, Petrick JL, Weinstein SJ, Albanes D, Gewirtz AT, McGlynn KA, Vijay-Kumar M. Deoxyribonuclease I Activity, Cell-Free DNA, and Risk of Liver Cancer in a Prospective Cohort. Jnci Cancer Spectrum. 2: pky083. PMID 30815627 DOI: 10.1093/Jncics/Pky083  0.222
1998 Gronert K, Gewirtz A, Madara JL, Serhan CN. Identification of a human enterocyte lipoxin A4 receptor that is regulated by interleukin (IL)-13 and interferon gamma and inhibits tumor necrosis factor alpha-induced IL-8 release. The Journal of Experimental Medicine. 187: 1285-94. PMID 9547339 DOI: 10.1084/Jem.187.8.1285  0.221
2023 Daniel N, Gewirtz AT, Chassaing B. counteracts the deleterious effects of dietary emulsifiers on microbiota and host metabolism. Gut. PMID 36646449 DOI: 10.1136/gutjnl-2021-326835  0.218
2019 Chassaing B, Gewirtz AT. Identification of Inner Mucus-Associated Bacteria by Laser Capture Microdissection. Cellular and Molecular Gastroenterology and Hepatology. 7: 157-160. PMID 30510996 DOI: 10.1016/J.Jcmgh.2018.09.009  0.217
2020 Ngo VL, Abo H, Kuczma M, Szurek E, Moore N, Medina-Contreras O, Nusrat A, Merlin D, Gewirtz AT, Ignatowicz L, Denning TL. IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 33087566 DOI: 10.1073/pnas.2004484117  0.216
2018 Lauer JM, Duggan CP, Ausman LM, Griffiths JK, Webb P, Agaba E, Nshakira N, Tran HQ, Gewirtz AT, Ghosh S. Biomarkers of maternal environmental enteric dysfunction are associated with shorter gestation and reduced length in newborn infants in Uganda. The American Journal of Clinical Nutrition. PMID 30247538 DOI: 10.1093/Ajcn/Nqy176  0.215
2017 Etienne-Mesmin L, Chassaing B, Adekunle O, Mattei LM, Edwards AN, McBride SM, Bushman FD, Gewirtz AT. Genome Sequence of a Toxin-Positive Clostridium difficile Strain Isolated from Murine Feces. Genome Announcements. 5. PMID 28385835 DOI: 10.1128/Genomea.00088-17  0.212
2006 Gewirtz A. Lipoxin analogs: novel anti-inflammatory mediators. Current Opinion in Investigational Drugs (London, England : 2000). 6: 1112-5. PMID 16312131  0.211
2019 Adeshirlarijaney A, Zou J, Tran H, Chassaing B, Gewirtz AT. Amelioration of metabolic syndrome by metformin associates with reduced indices of low-grade inflammation independently of the gut microbiota. American Journal of Physiology. Endocrinology and Metabolism. PMID 31573841 DOI: 10.1152/ajpendo.00245.2019  0.21
2021 Delaroque C, Chervy M, Gewirtz AT, Chassaing B. Social overcrowding impacts gut microbiota, promoting stress, inflammation, and dysglycemia. Gut Microbes. 13: 2000275. PMID 34856844 DOI: 10.1080/19490976.2021.2000275  0.207
2009 Klein KM, Ostrowicki G, Gewirtz AT, Sitaraman SK. Fabrication and bioconjugation of micro- and nanoscale structures intended for cancer-specific antigen detection Journal of Electronic Packaging, Transactions of the Asme. 131: 0210141-0210146. DOI: 10.1115/1.3103937  0.203
2023 Javmen A, Zou J, Nallar SC, Szmacinski H, Lakowicz JR, Gewirtz AT, Toshchakov VY. TLR5-Derived, TIR-Interacting Decoy Peptides to Inhibit TLR Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 36946775 DOI: 10.4049/jimmunol.2200394  0.202
2023 Daniel N, Wu GD, Walters W, Compher C, Ni J, Delaroque C, Albenberg L, Ley RE, Patterson AD, Lewis JD, Gewirtz AT, Chassaing B. Human intestinal microbiome determines individualized inflammatory response to dietary emulsifier carboxymethylcellulose consumption. Cellular and Molecular Gastroenterology and Hepatology. PMID 37931789 DOI: 10.1016/j.jcmgh.2023.11.001  0.201
2015 Miller L, Vegesna AK, Gewirtz A. Mo1922 Vector Volume Manometry of the Smooth Muscle Components of the Gastro-Esophageal Junction High-Pressure Zone in Normal Controls and GERD Patients Gastroenterology. 148: S-739-S-740. DOI: 10.1016/S0016-5085(15)32531-2  0.201
2021 Ngo VL, Gewirtz AT. Microbiota as a potentially-modifiable factor influencing COVID-19. Current Opinion in Virology. 49: 21-26. PMID 34000641 DOI: 10.1016/j.coviro.2021.04.005  0.199
2017 Locks LM, Mwiru RS, Mtisi E, Manji KP, McDonald CM, Liu E, Kupka R, Kisenge R, Aboud S, Gosselin K, Gillman M, Gewirtz AT, Fawzi WW, Duggan CP. Infant Nutritional Status and Markers of Environmental Enteric Dysfunction are Associated with Midchildhood Anthropometry and Blood Pressure in Tanzania. The Journal of Pediatrics. PMID 28499715 DOI: 10.1016/J.Jpeds.2017.04.005  0.196
2020 Zhang Z, Zou J, Shi Z, Zhang B, Etienne-Mesmin L, Wang Y, Shi X, Shao F, Chassaing B, Gewirtz AT. IL-22-induced cell extrusion and IL-18-induced cell death prevent and cure rotavirus infection. Science Immunology. 5. PMID 33008915 DOI: 10.1126/sciimmunol.abd2876  0.192
2021 Chassaing B, Compher C, Bonhomme B, Liu Q, Tian Y, Walters W, Nessel L, Delaroque C, Hao F, Gershuni V, Chau L, Ni J, Bewtra M, Albenberg L, Bretin A, ... ... Gewirtz AT, et al. Randomized controlled-feeding study of dietary emulsifier carboxymethylcellulose reveals detrimental impacts on the gut microbiota and metabolome. Gastroenterology. PMID 34774538 DOI: 10.1053/j.gastro.2021.11.006  0.191
2024 Cox RM, Wolf JD, Lieberman NA, Lieber CM, Kang HJ, Sticher ZM, Yoon JJ, Andrews MK, Govindarajan M, Krueger RE, Sobolik EB, Natchus MG, Gewirtz AT, deSwart RL, Kolykhalov AA, et al. Therapeutic mitigation of measles-like immune amnesia and exacerbated disease after prior respiratory virus infections in ferrets. Nature Communications. 15: 1189. PMID 38331906 DOI: 10.1038/s41467-024-45418-5  0.191
2003 Yu Y, Zeng H, Lyons S, Carlson A, Merlin D, Neish AS, Gewirtz AT. TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via a post-transcriptional mechanism Gastroenterology. 124: A482. DOI: 10.1016/S0016-5085(03)82441-1  0.19
2014 Pedersen O, Clément K, Gewirtz A. Slimming down via the microbiota. Nature Medicine. 19: 1374-5. PMID 24202385 DOI: 10.1038/nm.3398  0.19
2023 Ngo VL, Shi Z, Jiang B, Gewirtz AT. Segmented filamentous bacteria impede rotavirus infection via retinoic acid receptor-mediated signaling. Gut Microbes. 15: 2174407. PMID 36740862 DOI: 10.1080/19490976.2023.2174407  0.189
2013 Chassaing B, Gewirtz A. P-231 YI Food Additives Promote Intestinal Inflammation in Susceptible Hosts Inflammatory Bowel Diseases. 19: S115-S116. DOI: 10.1097/01.MIB.0000439029.44015.b6  0.186
2022 Hou Y, Sun X, Gheinani PT, Guan X, Sharma S, Zhou Y, Jin C, Yang Z, Naren AP, Yin J, Denning TL, Gewirtz AT, Liu Y, Xie Z, Li C. Epithelial SMYD5 Exaggerates IBD by Downregulating Mitochondrial Functions via Post-translational Control of PGC-1α Stability. Cellular and Molecular Gastroenterology and Hepatology. PMID 35643234 DOI: 10.1016/j.jcmgh.2022.05.006  0.182
2020 Shi Z, Zhao C, Mattei LM, Bittinger K, Jiang B, Gewirtz AT. Genome Sequence of a Segmented Filamentous Bacterium Strain That Confers a Rotavirus Resistance Phenotype in Mice. Microbiology Resource Announcements. 9. PMID 32139567 DOI: 10.1128/MRA.00073-20  0.182
2011 Yang VW, Anania FA, Gewirtz AT, Klapproth JM, Merlin D, Srinivasan S. Shanthi V. Sitaraman, MD, PhD: physician, scientist, educator, and humanitarian. Gastroenterology. 141: 1-3. PMID 21723981 DOI: 10.1053/J.Gastro.2011.05.031  0.175
2023 Ngo VL, Gewirtz AT. The STING That Tames Pro-inflammatory T-cells. Cellular and Molecular Gastroenterology and Hepatology. PMID 36893791 DOI: 10.1016/j.jcmgh.2023.02.008  0.171
2022 Zou J, Ngo VL, Wang Y, Wang Y, Gewirtz AT. Maternal fiber deprivation alters microbiota in offspring, resulting in low-grade inflammation and predisposition to obesity. Cell Host & Microbe. PMID 36493784 DOI: 10.1016/j.chom.2022.10.014  0.16
2023 Golonka RM, Yeoh BS, Saha P, Gohara A, Tummala R, Stepkowski S, Tiwari AK, Joe B, Gonzalez FJ, Gewirtz AT, Vijay-Kumar M. Loss of toll-like receptor 5 potentiates spontaneous hepatocarcinogenesis in farnesoid X receptor-deficient mice. Hepatology Communications. 7. PMID 37219858 DOI: 10.1097/HC9.0000000000000166  0.152
2015 Anitha M, Reichardt F, Tabatabavakili S, Nezami BG, Chassaing B, Mwangi S, Vijay-Kumar M, Gewirtz A, Srinivasan S. Intestinal Dysbiosis Contributes to the Delayed Gastrointestinal Transit in High-Fat Diet Fed Mice Cmgh Cellular and Molecular Gastroenterology and Hepatology. DOI: 10.1016/j.jcmgh.2015.12.008  0.152
2020 Viennois E, Pujada A, Sung J, Yang C, Gewirtz AT, Chassaing B, Merlin D. Impact of PepT1 deletion on microbiota composition and colitis requires multiple generations. Npj Biofilms and Microbiomes. 6: 27. PMID 32694535 DOI: 10.1038/s41522-020-0137-y  0.152
2019 Tran HQ, Mills RH, Peters NV, Holder MK, de Vries GJ, Knight R, Chassaing B, Gonzalez DJ, Gewirtz AT. Associations of the fecal microbial proteome composition and proneness to diet-induced obesity. Molecular & Cellular Proteomics : McP. PMID 31262998 DOI: 10.1074/Mcp.Ra119.001623  0.147
2019 Holder MK, Peters NV, Whylings J, Fields CT, Gewirtz AT, Chassaing B, de Vries GJ. Dietary emulsifiers consumption alters anxiety-like and social-related behaviors in mice in a sex-dependent manner. Scientific Reports. 9: 172. PMID 30655577 DOI: 10.1038/S41598-018-36890-3  0.141
2021 Um CY, Hodge RA, Tran HQ, Campbell PT, Gewirtz AT, McCullough ML. Association of Emulsifier and Highly Processed Food Intake with Circulating Markers of Intestinal Permeability and Inflammation in the Cancer Prevention Study-3 Diet Assessment Sub-Study. Nutrition and Cancer. 1-11. PMID 34353196 DOI: 10.1080/01635581.2021.1957947  0.14
2004 Sitaraman SV, Hoteit M, Gewirtz AT. Semapimod. Cytokine. Current Opinion in Investigational Drugs (London, England : 2000). 4: 1363-8. PMID 14758776  0.14
2022 Saha P, Mell B, Golonka RM, Bovilla VR, Abokor AA, Mei X, Yeoh BS, Doris PA, Gewirtz AT, Joe B, Vijay-Kumar M. Selective IgA Deficiency in Spontaneously Hypertensive Rats With Gut Dysbiosis. Hypertension (Dallas, Tex. : 1979). 101161HYPERTENSIONAH. PMID 35950503 DOI: 10.1161/HYPERTENSIONAHA.122.19307  0.135
2022 Delaroque C, Wu GD, Compher C, Ni J, Albenberg L, Liu Q, Tian Y, Patterson AD, Lewis JD, Gewirtz AT, Chassaing B. Diet standardization reduces intra-individual microbiome variation. Gut Microbes. 14: 2149047. PMID 36426908 DOI: 10.1080/19490976.2022.2149047  0.134
2024 Bonazzi E, Bretin A, Vigué L, Hao F, Patterson AD, Gewirtz AT, Chassaing B. Individualized microbiotas dictate the impact of dietary fiber on colitis sensitivity. Microbiome. 12: 5. PMID 38178260 DOI: 10.1186/s40168-023-01724-6  0.131
1999 Kowalska MA, Ratajczak J, Hoxie J, Brass LF, Gewirtz A, Poncz M, Ratajczak MZ. Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: Determination of response to stromal- derived factor-1 by megakaryocytes and platelets British Journal of Haematology. 104: 220-229. PMID 10050701 DOI: 10.1046/J.1365-2141.1999.01169.X  0.129
2023 Bretin A, Zou J, San Yeoh B, Ngo VL, Winer S, Winer DA, Reddivari L, Pellizzon M, Walters WA, Patterson AD, Ley R, Chassaing B, Vijay-Kumar M, Gewirtz AT. PSYLLIUM FIBER PROTECTS AGAINST COLITIS VIA ACTIVATION OF BILE ACID SENSOR FXR. Cellular and Molecular Gastroenterology and Hepatology. PMID 36828279 DOI: 10.1016/j.jcmgh.2023.02.007  0.123
2023 Yeoh BS, Golonka RM, Saha P, Kandalgaonkar MR, Tian Y, Osman I, Patterson AD, Gewirtz AT, Joe B, Vijay-Kumar M. Urine-based Detection of Congenital Portosystemic Shunt in C57BL/6 Mice. Function (Oxford, England). 4: zqad040. PMID 37575479 DOI: 10.1093/function/zqad040  0.121
2024 Ngo VL, Lieber CM, Kang HJ, Sakamoto K, Kuczma M, Plemper RK, Gewirtz AT. Intestinal microbiota programming of alveolar macrophages influences severity of respiratory viral infection. Cell Host & Microbe. PMID 38295788 DOI: 10.1016/j.chom.2024.01.002  0.12
2020 Lauer JM, Ghosh S, Ausman LM, Webb P, Bashaasha B, Agaba E, Turyashemererwa FM, Tran HQ, Gewirtz AT, Erhardt J, Duggan CP. Markers of Environmental Enteric Dysfunction Are Associated with Poor Growth and Iron Status in Rural Ugandan Infants. The Journal of Nutrition. PMID 32455424 DOI: 10.1093/Jn/Nxaa141  0.118
2021 Viennois E, Gewirtz AT, Chassaing B. Connecting the Dots: Dietary Fat, Microbiota Dysbiosis, Altered Metabolome, and Colon Cancer. Gastroenterology. PMID 34687737 DOI: 10.1053/j.gastro.2021.10.018  0.116
2020 Um C, Hodge R, Gewirtz A, Stevens V, Jacobs E, McCullough M. Emulsifier and Highly Processed Food Intake and Biomarkers of Intestinal Permeability and inflammation in the Cancer Prevention Study-3 Diet Assessment Sub-Study Current Developments in Nutrition. 4: 1498-1498. DOI: 10.1093/cdn/nzaa061_126  0.113
2002 Gewirtz AT, Sitaraman SV. Tacrolimus: Fujisawa Current Opinion in Investigational Drugs. 3: 1307-1311. PMID 12498005  0.112
2020 Vermandere K, Bostick RM, Tran HQ, Gewirtz AT, Barry EL, Rutherford RE, Seabrook ME, Fedirko V. Effects of Supplemental Calcium and Vitamin D on Circulating Biomarkers of Gut Barrier Function in Colon Adenoma Patients: a Randomized Clinical Trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 33229339 DOI: 10.1158/1940-6207.CAPR-20-0461  0.105
1999 Mazzucchelli L, Burritt JB, Jesaitis AJ, Nusrat A, Liang TW, Gewirtz AT, Schnell FJ, Parkos CA. Cell-specific peptide binding by human neutrophils Blood. 93: 1738-1748. PMID 10029604  0.102
1999 Mazzucchelli L, Burritt JB, Jesaitis AJ, Nusrat A, Liang TW, Gewirtz AT, Schnell FJ, Parkos CA. Cell-Specific Peptide Binding by Human Neutrophils Blood. 93: 1738-1748. DOI: 10.1182/blood.v93.5.1738.405a18_1738_1748  0.101
2023 Petrick JL, Florio AA, Zen J, Wang Y, Gewirtz AT, Pfeiffer RM, Loftus S, Inglefield J, Koshiol J, Yang B, Yu K, Hildesheim A, Chen CJ, Yang HI, Lee MH, et al. Biomarkers of gut barrier dysfunction and risk of hepatocellular carcinoma in the REVEAL-HBV and REVEAL-HCV Cohort Studies. International Journal of Cancer. PMID 36878686 DOI: 10.1002/ijc.34492  0.099
2022 Chassaing B, Gewirtz AT, Lewis JD. Impact of emulsifiers consumption / human microbiota interaction in health and diseases - pilot findings and needed follow-up. Gastroenterology. PMID 35595123 DOI: 10.1053/j.gastro.2022.05.021  0.096
2024 Sivapiromrat AK, Suppakitjanusant P, Wang Y, Hu C, Binongo J, Hunt WR, Weinstein S, Jathal I, Alvarez JA, Chassaing B, Ziegler TR, Gewirtz AT, Tangpricha V. Vitamin D and prebiotics for intestinal health in cystic fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 x 2 trial of administration of prebiotics and cholecalciferol (vitamin D) (Pre-D trial) in adults with cystic fibrosis. Contemporary Clinical Trials Communications. 38: 101278. PMID 38435430 DOI: 10.1016/j.conctc.2024.101278  0.095
2024 Sivapiromrat AK, Suppakitjanusant P, Wang Y, Binongo J, Hunt WR, Gewirtz A, Alvarez JA, Hu C, Weinstein S, Jathal I, Ziegler TR, Tangpricha V. Vitamin D and Prebiotics for Intestinal Health in Cystic Fibrosis: Rationale and design for a randomized, placebo-controlled, double-blind, 2 × 2 trial of administration of prebiotics and cholecalciferol (vitamin D ) (Pre-D Trial) in adults with cystic fibrosis. Medrxiv : the Preprint Server For Health Sciences. PMID 38343811 DOI: 10.1101/2024.01.04.24300860  0.094
1997 Seetoo KF, Schonhorn JE, Gewirtz AT, Zhou MJ, McMenamin ME, Delva L, Simons ER. A cytosolic calcium transient is not necessary for degranulation or oxidative burst in immune complex-stimulated neutrophils. Journal of Leukocyte Biology. 62: 329-40. PMID 9307071 DOI: 10.1002/JLB.62.3.329  0.094
2021 Zou J, Reddivari L, Shi Z, Li S, Wang Y, Bretin A, Ngo VL, Flythe M, Pellizzon M, Chassaing B, Gewirtz AT. Inulin fermentable fiber ameliorates type I diabetes via IL-22 and short-chain fatty acids in experimental models. Cellular and Molecular Gastroenterology and Hepatology. PMID 33940221 DOI: 10.1016/j.jcmgh.2021.04.014  0.082
2017 Rada B, Floyd M, Winn M, Chassaing B, Gewirtz A, Goldberg J, McCarter L. 72 Neutrophil extracellular trap formation triggered by Pseudomonas aeruginosa: relevance to cystic fibrosis lung disease Journal of Cystic Fibrosis. 16: S82-S83. DOI: 10.1016/S1569-1993(17)30436-8  0.071
2024 Golonka RM, San Yeoh B, Saha P, Tian Y, Chiang JYL, Patterson AD, Gewirtz AT, Joe B, Vijay-Kumar M. Sex dimorphic effects of bile acid metabolism in liver cancer in mice. Cellular and Molecular Gastroenterology and Hepatology. PMID 38262588 DOI: 10.1016/j.jcmgh.2024.01.011  0.061
2023 Najjar RS, Gewirtz AT. Plant-Based Diets: A Path to Ending CVD as We Know It? Nutrients. 15. PMID 37630797 DOI: 10.3390/nu15163608  0.058
2005 Gewirtz AT, Sitaraman SV. Technology evaluation: Alicaforsen, Isis Current Opinion in Molecular Therapeutics. 7: 273-281. PMID 15977426  0.052
2023 Fayfman M, Gewirtz AT, Delaroque C, Blanco G, Gibanica S, Srinivasan S, Chassaing B. Microbiome differences related to metformin intolerance among Black individuals with diabetes, a pilot cross-sectional study. Metabolism Open. 20: 100256. PMID 38115865 DOI: 10.1016/j.metop.2023.100256  0.05
2022 Kirby MA, Lauer JM, Muhihi A, Ulenga N, Aboud S, Liu E, Choy RKM, Arndt MB, Kou J, Gewirtz A, Fawzi WW, Duggan CP, Manji KP, Sudfeld CR. Biomarkers of environmental enteric dysfunction and adverse birth outcomes: An observational study among pregnant women living with HIV in Tanzania. Ebiomedicine. 84: 104257. PMID 36130475 DOI: 10.1016/j.ebiom.2022.104257  0.044
2023 Lauer JM, Kirby MA, Muhihi A, Ulenga N, Aboud S, Liu E, Choy RKM, Arndt MB, Kou J, Fawzi W, Gewirtz A, Sudfeld CR, Manji KP, Duggan CP. Assessing environmental enteric dysfunction via multiplex assay and its relation to growth and development among HIV-exposed uninfected Tanzanian infants. Plos Neglected Tropical Diseases. 17: e0011181. PMID 36943785 DOI: 10.1371/journal.pntd.0011181  0.044
2019 Lauer J, Smith E, Ghosh S, Ausman L, Webb P, Bashaasha B, Agaba E, Tran H, Gewirtz A, Duggan C. Water Source Correlates with E. Coli Contamination and Markers of Environmental Enteric Dysfunction in Rural Ugandan Infants (P10-123-19). Current Developments in Nutrition. 3. PMID 31223694 DOI: 10.1093/cdn/nzz034.P10-123-19  0.031
2022 San Yeoh B, Saha P, Golonka RM, Zou J, Petrick JL, Abokor AA, Xiao X, Bovilla VR, Bretin ACA, Rivera-Esteban J, Parisi D, Florio AA, Weinstein SJ, Albanes D, Freeman GJ, ... ... Gewirtz AT, et al. Enterohepatic shunt-driven cholemia predisposes to liver cancer. Gastroenterology. PMID 35988658 DOI: 10.1053/j.gastro.2022.08.033  0.031
2016 Chassaing B, Tran H, Gewirtz A. O-007 Colitis Vaccine Inflammatory Bowel Diseases. 22: S3. DOI: 10.1097/01.MIB.0000480045.11503.c5  0.024
2019 Bretin A, Gewirtz AT. Aluminum Meddles With Visceral Pain Perception. Cellular and Molecular Gastroenterology and Hepatology. 7: 235-236. PMID 30539790 DOI: 10.1016/j.jcmgh.2018.10.005  0.01
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