Ettore J Rastelli, Ph.D.

Affiliations: 
2008-2012 Chemistry University of Arkansas, Fayetteville, Fayetteville, AR, United States 
 2012-2018 Chemistry University of Houston, Houston, TX, United States 
 2018- Chemistry University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Organic Chemistry
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Publications

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Lazo JS, Isbell KN, Vasa SA, et al. (2023) Disruption of ovarian cancer STAT3 and p38 signaling with a small molecule inhibitor of PTP4A3 phosphatase. The Journal of Pharmacology and Experimental Therapeutics
Lazo JS, Sharlow ER, Cornelison R, et al. (2021) Credentialing and Pharmacologically Targeting PTP4A3 Phosphatase as a Molecular Target for Ovarian Cancer. Biomolecules. 11
Rastelli EJ, Sannino S, Hart DJ, et al. (2021) Synthesis and evaluation of bifunctional PTP4A3 phosphatase inhibitors activating the ER stress pathway. Bioorganic & Medicinal Chemistry Letters. 46: 128167
Czub MP, Boulton AM, Rastelli EJ, et al. (2020) Structure of the complex of an iminopyridinedione PTP4A3 phosphatase inhibitor with human serum albumin. Molecular Pharmacology
Coltart DM, Uddin N, Knight J, et al. (2019) On the Mechanism of the Asymmetric Aldol Addition of Chiral N-Amino Cyclic Carbamate Hydrazones: Evidence of Non-Curtin-Hammett Behavior. Chemistry (Weinheim An Der Bergstrasse, Germany)
Lazo JS, Blanco IK, Tasker NR, et al. (2019) Next-Generation Cell-active Inhibitors of the Undrugged Oncogenic PTP4A3 Phosphatase. The Journal of Pharmacology and Experimental Therapeutics
Tasker NR, Rastelli EJ, Burnett JC, et al. (2019) Tapping the therapeutic potential of protein tyrosine phosphatase 4A with small molecule inhibitors. Bioorganic & Medicinal Chemistry Letters
Ferguson MW, Gerak CAN, Chow CCT, et al. (2019) The antimalarial drug mefloquine enhances TP53 premature termination codon readthrough by aminoglycoside G418. Plos One. 14: e0216423
Tasker NR, Rastelli EJ, Blanco IK, et al. (2019) In-flow photooxygenation of aminothienopyridinones generates iminopyridinedione PTP4A3 phosphatase inhibitors. Organic & Biomolecular Chemistry
Rastelli EJ, Coltart, DM. (2018) Synthesis and biological activity of apratoxin derivatives Tetrahedron. 74: 2269-2290
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