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Michael R. Leach, Ph.D. - Publications

Affiliations: 
2004 University of Toronto, Toronto, ON, Canada 
Area:
Protein chaperones in the ER, MHC processing
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10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2008 Dias AV, Mulvihill CM, Leach MR, Pickering IJ, George GN, Zamble DB. Structural and biological analysis of the metal sites of Escherichia coli hydrogenase accessory protein HypB. Biochemistry. 47: 11981-91. PMID 18942856 DOI: 10.1021/Bi801337X  0.458
2007 Leach MR, Zhang JW, Zamble DB. The role of complex formation between the Escherichia coli hydrogenase accessory factors HypB and SlyD. The Journal of Biological Chemistry. 282: 16177-86. PMID 17426034 DOI: 10.1074/Jbc.M610834200  0.503
2007 Leach MR, Zamble DB. Metallocenter assembly of the hydrogenase enzymes. Current Opinion in Chemical Biology. 11: 159-65. PMID 17275396 DOI: 10.1016/J.Cbpa.2007.01.011  0.454
2005 Leach MR, Sandal S, Sun H, Zamble DB. Metal binding activity of the Escherichia coli hydrogenase maturation factor HypB. Biochemistry. 44: 12229-38. PMID 16142921 DOI: 10.1021/Bi050993J  0.463
2005 Paquet ME, Leach MR, Williams DB. In vitro and in vivo assays to assess the functions of calnexin and calreticulin in ER protein folding and quality control. Methods (San Diego, Calif.). 35: 338-47. PMID 15804605 DOI: 10.1016/J.Ymeth.2004.10.005  0.552
2004 Leach MR, Williams DB. Lectin-deficient calnexin is capable of binding class I histocompatibility molecules in vivo and preventing their degradation. The Journal of Biological Chemistry. 279: 9072-9. PMID 14699098 DOI: 10.1074/Jbc.M310788200  0.565
2002 Leach MR, Cohen-Doyle MF, Thomas DY, Williams DB. Localization of the lectin, ERp57 binding, and polypeptide binding sites of calnexin and calreticulin. The Journal of Biological Chemistry. 277: 29686-97. PMID 12052826 DOI: 10.1074/jbc.M202405200  0.546
2002 Cherif S, Leach MR, Williams DB, Monneret C. Synthesis of a molecular mimic of the Glc1Man9 oligoside as potential inhibitor of calnexin binding to DeltaF508 CFTR protein. Bioorganic & Medicinal Chemistry Letters. 12: 1237-40. PMID 11965361 DOI: 10.1016/S0960-894X(02)00151-8  0.564
2000 Leach M, Williams D. Mapping of the lectin, ERp57-binding and chaperone sites of calnexin and calreticulin Biochemical Society Transactions. 28: A463-A463. DOI: 10.1042/Bst028A463  0.426
1999 Saito Y, Ihara Y, Leach MR, Cohen-Doyle MF, Williams DB. Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins. The Embo Journal. 18: 6718-29. PMID 10581245 DOI: 10.1093/Emboj/18.23.6718  0.6
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