Wenjun Zhang - Publications

Affiliations: 
Chemistry University of California, Berkeley, Berkeley, CA, United States 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jenner M, Hai Y, Nguyen HH, Passmore M, Skyrud W, Kim J, Garg NK, Zhang W, Ogorzalek Loo RR, Tang Y. Elucidating the molecular programming of a nonlinear non-ribosomal peptide synthetase responsible for fungal siderophore biosynthesis. Nature Communications. 14: 2832. PMID 37198174 DOI: 10.1038/s41467-023-38484-8  0.633
2022 Yang C, Zhang L, Zhang W, Huang C, Zhu Y, Jiang X, Liu W, Zhao M, De BC, Zhang C. Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation. Nature Communications. 13: 5386. PMID 36104338 DOI: 10.1038/s41467-022-33131-0  0.304
2020 Porterfield WB, Poenateetai N, Zhang W. Engineered Biosynthesis of Alkyne-Tagged Polyketides by Type I PKSs. Iscience. 23: 100938. PMID 32146323 DOI: 10.1016/J.Isci.2020.100938  0.348
2020 Li JS, Barber CC, Herman NA, Cai W, Zafrir E, Du Y, Zhu X, Skyrud W, Zhang W. Investigation of secondary metabolism in the industrial butanol hyper-producer Clostridium saccharoperbutylacetonicum N1-4. Journal of Industrial Microbiology & Biotechnology. PMID 32103460 DOI: 10.1007/S10295-020-02266-8  0.596
2020 Skyrud W, Flores ADR, Zhang W. Biosynthesis of Cyclohexanecarboxyl-CoA Highlights a Promiscuous Shikimoyl-CoA Synthetase and a FAD-Dependent Dehydratase Acs Catalysis. 10: 3360-3364. DOI: 10.1021/Acscatal.0C00406  0.371
2019 Zhang B, Rajakovich LJ, Van Cura D, Blaesi EJ, Mitchell AJ, Tysoe CR, Zhu X, Streit BR, Rui Z, Zhang W, Boal AK, Krebs C, Bollinger JM. Substrate-triggered Formation of a Peroxo-Fe(III/III) Intermediate during Fatty Acid Decarboxylation by UndA. Journal of the American Chemical Society. PMID 31487162 DOI: 10.1021/Jacs.9B06093  0.683
2019 Seidel J, Miao Y, Porterfield W, Cai W, Zhu X, Kim SJ, Hu F, Bhattarai-Kline S, Min W, Zhang W. Structure-activity-distribution relationship study of anti-cancer antimycin-type depsipeptides. Chemical Communications (Cambridge, England). PMID 31317975 DOI: 10.1039/C9Cc03051D  0.566
2018 Su M, Zhu X, Zhang W. Probing the Acyl Carrier Protein-Enzyme Interactions within Terminal Alkyne Biosynthetic Machinery. Aiche Journal. American Institute of Chemical Engineers. 64: 4255-4262. PMID 30983594 DOI: 10.1002/Aic.16355  0.592
2018 Twigg FF, Cai W, Huang W, Liu J, Sato M, Perez T, Geng J, Dror M, Montanez I, Tong T, Lee H, Zhang W. Identifying the Biosynthetic Gene Cluster for Triacsins with an N-hydroxytriazene Moiety. Chembiochem : a European Journal of Chemical Biology. PMID 30589194 DOI: 10.1002/Cbic.201800762  0.335
2018 Li JS, Barber CC, Zhang W. Natural products from anaerobes. Journal of Industrial Microbiology & Biotechnology. PMID 30284140 DOI: 10.1007/S10295-018-2086-5  0.341
2018 Harris N, Born D, Cai W, Huang Y, Martin J, Khalaf R, Drennan C, Zhang W. Isonitrile Formation by a Non-heme Iron(II)-Dependent Oxidase/Decarboxylase. Angewandte Chemie (International Ed. in English). PMID 29906336 DOI: 10.1002/Anie.201804307  0.345
2018 Huang C, Yang C, Zhang W, Zhang L, De BC, Zhu Y, Jiang X, Fang C, Zhang Q, Yuan CS, Liu HW, Zhang C. Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines. Nature Communications. 9: 2088. PMID 29802272 DOI: 10.1038/S41467-018-04487-Z  0.537
2018 Zhu X, Zhang W. Terminal Alkyne Biosynthesis in Marine Microbes. Methods in Enzymology. 604: 89-112. PMID 29779667 DOI: 10.1016/Bs.Mie.2018.01.040  0.624
2018 Skyrud W, Liu J, Thankachan D, Cabrera M, Seipke RF, Zhang W. Biosynthesis of the 15-membered ring depsipeptide neoantimycin. Acs Chemical Biology. PMID 29693372 DOI: 10.1021/Acschembio.8B00298  0.428
2017 Liu J, Kaganjo J, Zhang W, Zeilstra-Ryalls J. Investigating the bifunctionality of cyclizing and "classical" 5-aminolevulinate synthases. Protein Science : a Publication of the Protein Society. PMID 29027286 DOI: 10.1002/Pro.3324  0.421
2017 Cai W, Zhang W. Engineering modular polyketide synthases for production of biofuels and industrial chemicals. Current Opinion in Biotechnology. 50: 32-38. PMID 28946011 DOI: 10.1016/J.Copbio.2017.08.017  0.349
2017 Harris NC, Sato M, Herman NA, Twigg F, Cai W, Liu J, Zhu X, Downey J, Khalaf R, Martin J, Koshino H, Zhang W. Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 28634299 DOI: 10.1073/Pnas.1705016114  0.611
2016 Herman NA, Li J, Bedi R, Turchi B, Liu X, Miller MJ, Zhang W. Development of a High-Efficiency Transformation Method and Implementation of Rational Metabolic Engineering for the Industrial Butanol Hyper-Producer Clostridium saccharoperbutylacetonicum strain N1-4. Applied and Environmental Microbiology. PMID 27836845 DOI: 10.1128/Aem.02942-16  0.318
2016 Herman NA, Zhang W. Enzymes for fatty acid-based hydrocarbon biosynthesis. Current Opinion in Chemical Biology. 35: 22-28. PMID 27573483 DOI: 10.1016/J.Cbpa.2016.08.009  0.342
2016 Zhu X, Shieh P, Su M, Bertozzi CR, Zhang W. A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool. Chemical Communications (Cambridge, England). PMID 27561030 DOI: 10.1039/C6Cc05990B  0.574
2016 Liu J, Zhu X, Kim SJ, Zhang W. Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities. Natural Product Reports. PMID 27307039 DOI: 10.1039/C6Np00004E  0.611
2016 Chen Z, Zhang W, Tang X, Fan H, Xie X, Wan Q, Wu X, Tang JZ. Extraction and characterization of polysaccharides from Semen Cassiae by microwave-assisted aqueous two-phase extraction coupled with spectroscopy and HPLC. Carbohydrate Polymers. 144: 263-70. PMID 27083817 DOI: 10.1016/j.carbpol.2016.02.063  0.337
2016 Fan W, Ye Y, Chen Z, Shao Y, Xie X, Zhang W, Liu HP, Li C. Metabolic product response profiles of Cherax quadricarinatus towards white spot syndrome virus infection. Developmental and Comparative Immunology. PMID 27068762 DOI: 10.1016/j.dci.2016.04.006  0.371
2016 Zhang W, Liu J. Recent Advances in Understanding and Engineering Polyketide Synthesis. F1000research. 5. PMID 26962443 DOI: 10.12688/F1000Research.7326.1  0.367
2016 Yang ZH, Chu YM, Zhang W. Accurate approximations for the complete elliptic integral of the second kind Journal of Mathematical Analysis and Applications. 438: 875-888. DOI: 10.1016/j.jmaa.2016.02.035  0.36
2015 Fan H, Wu Y, Zhou X, Xia J, Zhang W, Song Y, Liu F, Chen Y, Zhang L, Gao X, Gao H, Li J. Pathway-Based Genome-Wide Association Studies for Two Meat Production Traits in Simmental Cattle. Scientific Reports. 5: 18389. PMID 26672757 DOI: 10.1038/srep18389  0.361
2015 Liu J, Zhu X, Zhang W. Identifying the Minimal Enzymes Required for Biosynthesis of Epoxyketone Proteasome Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 26477320 DOI: 10.1002/Cbic.201500496  0.647
2015 Huang W, Kim SJ, Liu J, Zhang W. Identification of the Polyketide Biosynthetic Machinery for the Indolizidine Alkaloid Cyclizidine. Organic Letters. PMID 26473429 DOI: 10.1021/Acs.Orglett.5B02707  0.374
2015 Rui Z, Zhang W. Engineering Biosynthesis of Non-ribosomal Peptides and Polyketides by Directed Evolution. Current Topics in Medicinal Chemistry. PMID 26456467 DOI: 10.2174/1568026616666151012112045  0.377
2015 Zhu X, Su M, Manickam K, Zhang W. Bacterial Genome Mining of Enzymatic Tools for Alkyne Biosynthesis. Acs Chemical Biology. PMID 26441143 DOI: 10.1021/Acschembio.5B00641  0.661
2015 Rui Z, Huang W, Xu F, Han M, Liu X, Lin S, Zhang W. Sparsomycin Biosynthesis Highlights Unusual Module Architecture and Processing Mechanism in Non-ribosomal Peptide Synthetase. Acs Chemical Biology. PMID 26046698 DOI: 10.1021/Acschembio.5B00284  0.462
2015 Zhu X, Zhang W. Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications. Frontiers in Chemistry. 3: 11. PMID 25815285 DOI: 10.3389/Fchem.2015.00011  0.591
2015 Zhu X, Liu J, Zhang W. De novo biosynthesis of terminal alkyne-labeled natural products. Nature Chemical Biology. 11: 115-20. PMID 25531891 DOI: 10.1038/Nchembio.1718  0.621
2015 Liu J, Zhu X, Seipke RF, Zhang W. Biosynthesis of antimycins with a reconstituted 3-formamidosalicylate pharmacophore in Escherichia coli. Acs Synthetic Biology. 4: 559-65. PMID 25275920 DOI: 10.1021/Sb5003136  0.646
2015 Rui Z, Harris NC, Zhu X, Huang W, Zhang W. Discovery of a Family of Desaturase-Like Enzymes for 1-Alkene Biosynthesis Acs Catalysis. 5: 7091-7094. DOI: 10.1021/Acscatal.5B01842  0.609
2014 Rui Z, Li X, Zhu X, Liu J, Domigan B, Barr I, Cate JH, Zhang W. Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase. Proceedings of the National Academy of Sciences of the United States of America. 111: 18237-42. PMID 25489112 DOI: 10.1073/Pnas.1419701112  0.636
2014 Liu J, Ng T, Rui Z, Ad O, Zhang W. Unusual acetylation-dependent reaction cascade in the biosynthesis of the pyrroloindole drug physostigmine. Angewandte Chemie (International Ed. in English). 53: 136-9. PMID 24227628 DOI: 10.1002/Anie.201308069  0.337
2013 Rui Z, Sandy M, Jung B, Zhang W. Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites Chemistry and Biology. 20: 879-887. PMID 23890006 DOI: 10.1016/J.Chembiol.2013.05.006  0.403
2013 Sandy M, Zhu X, Rui Z, Zhang W. Characterization of AntB, a promiscuous acyltransferase involved in antimycin biosynthesis Organic Letters. 15: 3396-3399. PMID 23772837 DOI: 10.1021/Ol4014365  0.634
2012 Rui Z, Ye M, Wang S, Fujikawa K, Akerele B, Aung M, Floss HG, Zhang W, Yu TW. Insights into a divergent phenazine biosynthetic pathway governed by a plasmid-born esmeraldin gene cluster. Chemistry & Biology. 19: 1116-25. PMID 22999880 DOI: 10.1016/J.Chembiol.2012.07.025  0.372
2012 Sandy M, Rui Z, Gallagher J, Zhang W. Enzymatic synthesis of dilactone scaffold of antimycins Acs Chemical Biology. 7: 1956-1961. PMID 22971101 DOI: 10.1021/Cb300416W  0.444
2011 Ames BD, Lee MY, Moody C, Zhang W, Tang Y, Tsai SC. Structural and biochemical characterization of ZhuI aromatase/cyclase from the R1128 polyketide pathway. Biochemistry. 50: 8392-406. PMID 21870821 DOI: 10.1021/Bi200593M  0.762
2011 Walsh CT, Zhang W. Chemical logic and enzymatic machinery for biological assembly of peptidyl nucleoside antibiotics. Acs Chemical Biology. 6: 1000-7. PMID 21851099 DOI: 10.1021/Cb200284P  0.504
2011 Zhang W, Ntai I, Kelleher NL, Walsh CT. tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 108: 12249-53. PMID 21746899 DOI: 10.1073/Pnas.1109539108  0.632
2011 Zhang W, Ames BD, Walsh CT. Identification of phenylalanine 3-hydroxylase for meta-tyrosine biosynthesis. Biochemistry. 50: 5401-3. PMID 21615132 DOI: 10.1021/Bi200733C  0.756
2011 Zhang W, Ntai I, Bolla ML, Malcolmson SJ, Kahne D, Kelleher NL, Walsh CT. Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. Journal of the American Chemical Society. 133: 5240-3. PMID 21417270 DOI: 10.1021/Ja2011109  0.762
2011 Qiao K, Zhou H, Xu W, Zhang W, Garg N, Tang Y. A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines. Organic Letters. 13: 1758-61. PMID 21384820 DOI: 10.1021/Ol200288W  0.642
2010 Zhang W, Heemstra JR, Walsh CT, Imker HJ. Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins. Biochemistry. 49: 9946-7. PMID 20964365 DOI: 10.1021/Bi101539B  0.518
2010 Zhang W, Ostash B, Walsh CT. Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 107: 16828-33. PMID 20826445 DOI: 10.1073/Pnas.1011557107  0.53
2010 Zhang W, Bolla ML, Kahne D, Walsh CT. A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis. Journal of the American Chemical Society. 132: 6402-11. PMID 20394362 DOI: 10.1021/Ja1002845  0.561
2010 Yan M, Du J, Gu Z, Liang M, Hu Y, Zhang W, Priceman S, Wu L, Zhou ZH, Liu Z, Segura T, Tang Y, Lu Y. A novel intracellular protein delivery platform based on single-protein nanocapsules. Nature Nanotechnology. 5: 48-53. PMID 19935648 DOI: 10.1038/Nnano.2009.341  0.397
2009 Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/J.Chembiol.2009.09.017  0.751
2009 Wang P, Zhang W, Zhan J, Tang Y. Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1544-50. PMID 19472250 DOI: 10.1002/Cbic.200900122  0.515
2009 Zhang W, Tang Y. In vitro analysis of type II polyketide synthase. Methods in Enzymology. 459: 367-93. PMID 19362648 DOI: 10.1016/S0076-6879(09)04616-3  0.448
2008 Zhang W, Li Y, Tang Y. Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 105: 20683-8. PMID 19075227 DOI: 10.1073/Pnas.0809084105  0.698
2008 Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J. Identifying the minimal enzymes required for anhydrotetracycline biosynthesis. Journal of the American Chemical Society. 130: 6068-9. PMID 18422316 DOI: 10.1021/Ja800951E  0.537
2008 Zhang W, Tang Y. Combinatorial biosynthesis of natural products. Journal of Medicinal Chemistry. 51: 2629-33. PMID 18393406 DOI: 10.1021/Jm701269V  0.43
2008 Ames BD, Korman TP, Zhang W, Smith P, Vu T, Tang Y, Tsai SC. Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides. Proceedings of the National Academy of Sciences of the United States of America. 105: 5349-54. PMID 18388203 DOI: 10.1073/Pnas.0709223105  0.774
2008 Ma SM, Zhan J, Xie X, Watanabe K, Tang Y, Zhang W. Redirecting the cyclization steps of fungal polyketide synthase. Journal of the American Chemical Society. 130: 38-9. PMID 18072779 DOI: 10.1021/Ja078091O  0.686
2007 Ma SM, Zhan J, Watanabe K, Xie X, Zhang W, Wang CC, Tang Y. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. Journal of the American Chemical Society. 129: 10642-3. PMID 17696354 DOI: 10.1021/Ja074865P  0.665
2007 Zhang W, Watanabe K, Wang CC, Tang Y. Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway. The Journal of Biological Chemistry. 282: 25717-25. PMID 17631493 DOI: 10.1074/Jbc.M703437200  0.534
2007 Zhang W, Wilke BI, Zhan J, Watanabe K, Boddy CN, Tang Y. A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis. Journal of the American Chemical Society. 129: 9304-5. PMID 17625867 DOI: 10.1021/Ja0736919  0.503
2006 Zhang W, Watanabe K, Wang CC, Tang Y. Heterologous biosynthesis of amidated polyketides with novel cyclization regioselectivity from oxytetracycline polyketide synthase. Journal of Natural Products. 69: 1633-6. PMID 17125237 DOI: 10.1021/Np060290I  0.501
2006 Zhang W, Ames BD, Tsai SC, Tang Y. Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. Applied and Environmental Microbiology. 72: 2573-80. PMID 16597959 DOI: 10.1128/Aem.72.4.2573-2580.2006  0.754
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