Darren W. Dawson - Publications

Affiliations: 
Electrical & Computer Engineering Clemson University, Clemson, SC, United States 
Area:
Electronics and Electrical, Robotics

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Donahue TR, Dawson DW. Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality. Trends in Endocrinology and Metabolism: Tem. PMID 27461042 DOI: 10.1016/j.tem.2016.06.009  0.52
2016 Moris M, Dawson DW, Jiang J, Lewis J, Nassar A, Takeuchi KK, Lay AR, Zhai Q, Donahue TR, Kelly KA, Crawford HC, Wallace M. Plectin-1 as a Biomarker of Malignant Progression in Intraductal Papillary Mucinous Neoplasms: A Multicenter Study. Pancreas. PMID 27101571 DOI: 10.1097/MPA.0000000000000652  0.8
2016 Principe DR, DeCant B, Mascarinas E, Wayne E, Diaz A, Akagi N, Hwang RF, Pasche B, Dawson DW, Fang D, Bentrem DJ, Munshi HG, Jung B, Grippo PJ. TGFβ signaling in the pancreatic tumor microenvironment promotes fibrosis and immune evasion to facilitate tumorigenesis. Cancer Research. PMID 26980767 DOI: 10.1158/0008-5472.CAN-15-1293  0.8
2016 Toste PA, Nguyen AH, Kadera BE, Duong M, Wu N, Gawlas I, Tran LM, Bikhchandani M, Li L, Patel SG, Dawson DW, Donahue TR. Chemotherapy-induced Inflammatory Gene Signature and Pro-tumorigenic Phenotype in Pancreatic CAFs via Stress-associated MAPK. Molecular Cancer Research : McR. PMID 26979711 DOI: 10.1158/1541-7786.MCR-15-0348  0.8
2016 Stark AP, Sacks GD, Rochefort MM, Donahue TR, Reber HA, Tomlinson JS, Dawson DW, Eibl G, Hines OJ. Long-term survival in patients with pancreatic ductal adenocarcinoma. Surgery. PMID 26847803 DOI: 10.1016/j.surg.2015.12.024  0.52
2015 Hertzer KM, Xu M, Moro A, Dawson DW, Du L, Li G, Chang HH, Stark AP, Jung X, Hines OJ, Eibl G. Robust Early Inflammation of the Peripancreatic Visceral Adipose Tissue During Diet-Induced Obesity in the KrasG12D Model of Pancreatic Cancer. Pancreas. PMID 26495779 DOI: 10.1097/MPA.0000000000000497  0.8
2015 Williams JL, Nguyen AH, Rochefort M, Muthusamy VR, Wainberg ZA, Dawson DW, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Pancreatic cancer patients with lymph node involvement by direct tumor extension have similar survival to those with node-negative disease. Journal of Surgical Oncology. 112: 396-402. PMID 26303811 DOI: 10.1002/jso.24011  0.52
2015 Arensman MD, Nguyen P, Kershaw KM, Lay AR, Ostertag-Hill CA, Sherman MH, Downes M, Liddle C, Evans RM, Dawson DW. Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer. Molecular Cancer Research : McR. PMID 26224368 DOI: 10.1158/1541-7786.MCR-15-0204  0.8
2015 Thompson MJ, Rubbi L, Dawson DW, Donahue TR, Pellegrini M. Pancreatic cancer patient survival correlates with DNA methylation of pancreas development genes. Plos One. 10: e0128814. PMID 26039411 DOI: 10.1371/journal.pone.0128814  0.8
2015 Toste PA, Li L, Kadera BE, Nguyen AH, Tran LM, Wu N, Madnick DL, Patel SG, Dawson DW, Donahue TR. p85α is a microRNA target and affects chemosensitivity in pancreatic cancer. The Journal of Surgical Research. 196: 285-93. PMID 25846727 DOI: 10.1016/j.jss.2015.02.071  0.8
2015 Roy N, Malik S, Villanueva KE, Urano A, Lu X, Von Figura G, Seeley ES, Dawson DW, Collisson EA, Hebrok M. Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation. Genes & Development. 29: 658-71. PMID 25792600 DOI: 10.1101/gad.256628.114  0.8
2015 Liou GY, Döppler H, Necela B, Edenfield B, Zhang L, Dawson DW, Storz P. Mutant KRAS-induced expression of ICAM-1 in pancreatic acinar cells causes attraction of macrophages to expedite the formation of precancerous lesions. Cancer Discovery. 5: 52-63. PMID 25361845 DOI: 10.1158/2159-8290.CD-14-0474  0.8
2015 Kadera BE, Toste PA, Wu N, Li L, Nguyen AH, Dawson DW, Donahue TR. Low expression of the E3 ubiquitin ligase CBL confers chemoresistance in human pancreatic cancer and is targeted by epidermal growth factor receptor inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 157-65. PMID 25348515 DOI: 10.1158/1078-0432.CCR-14-0610  0.8
2015 Chen R, Dawson DW, Pan S, Ottenhof NA, de Wilde RF, Wolfgang CL, May DH, Crispin DA, Lai LA, Lay AR, Waghray M, Wang S, McIntosh MW, Simeone DM, Maitra A, et al. Proteins associated with pancreatic cancer survival in patients with resectable pancreatic ductal adenocarcinoma. Laboratory Investigation; a Journal of Technical Methods and Pathology. 95: 43-55. PMID 25347153 DOI: 10.1038/labinvest.2014.128  0.8
2015 Williams JL, Nguyen AH, Rochefort M, Muthusamy VR, Wainberg ZA, Dawson DW, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Pancreatic cancer patients with lymph node involvement by direct tumor extension have similar survival to those with node-negative disease Journal of Surgical Oncology. DOI: 10.1002/jso.24011  0.52
2014 Nguyen D, Dawson DW, Hines OJ, Reber HA, Donahue TR. Mucinous cystic neoplasms of the pancreas: are we overestimating malignant potential? The American Surgeon. 80: 915-9. PMID 25264629  0.52
2014 Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, et al. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159: 80-93. PMID 25259922 DOI: 10.1016/j.cell.2014.08.007  0.8
2014 Arensman MD, Telesca D, Lay AR, Kershaw KM, Wu N, Donahue TR, Dawson DW. The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth. Molecular Cancer Therapeutics. 13: 2303-14. PMID 25082960 DOI: 10.1158/1535-7163.MCT-13-1005  0.8
2014 von Figura G, Fukuda A, Roy N, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J, Mueller WF, Busch A, Hertel KJ, Hebrok M. The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma. Nature Cell Biology. 16: 255-67. PMID 24561622 DOI: 10.1038/ncb2916  0.8
2014 Kadera BE, Sunjaya DB, Isacoff WH, Li L, Hines OJ, Tomlinson JS, Dawson DW, Rochefort MM, Donald GW, Clerkin BM, Reber HA, Donahue TR. Locally advanced pancreatic cancer: association between prolonged preoperative treatment and lymph-node negativity and overall survival. Jama Surgery. 149: 145-53. PMID 24306217 DOI: 10.1001/jamasurg.2013.2690  0.8
2014 Arensman MD, Kovochich AN, Kulikauskas RM, Lay AR, Yang PT, Li X, Donahue T, Major MB, Moon RT, Chien AJ, Dawson DW. WNT7B mediates autocrine Wnt/β-catenin signaling and anchorage-independent growth in pancreatic adenocarcinoma. Oncogene. 33: 899-908. PMID 23416978 DOI: 10.1038/onc.2013.23  0.8
2013 Toste PA, Kadera BE, Tatishchev SF, Dawson DW, Clerkin BM, Muthusamy R, Watson R, Tomlinson JS, Hines OJ, Reber HA, Donahue TR. Nonfunctional pancreatic neuroendocrine tumors <2 cm on preoperative imaging are associated with a low incidence of nodal metastasis and an excellent overall survival. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 17: 2105-13. PMID 24101447 DOI: 10.1007/s11605-013-2360-9  0.8
2013 Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC. Response to comments on: Butler et al. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes 2013;62:2595-2604. Diabetes. 62: e19-22. PMID 24065800 DOI: 10.2337/db13-0996  0.8
2013 Kadera BE, Li L, Toste PA, Wu N, Adams C, Dawson DW, Donahue TR. MicroRNA-21 in pancreatic ductal adenocarcinoma tumor-associated fibroblasts promotes metastasis. Plos One. 8: e71978. PMID 23991015 DOI: 10.1371/journal.pone.0071978  0.8
2013 Dawson DW, Hertzer K, Moro A, Donald G, Chang HH, Go VL, Pandol SJ, Lugea A, Gukovskaya AS, Li G, Hines OJ, Rozengurt E, Eibl G. High-fat, high-calorie diet promotes early pancreatic neoplasia in the conditional KrasG12D mouse model. Cancer Prevention Research (Philadelphia, Pa.). 6: 1064-73. PMID 23943783 DOI: 10.1158/1940-6207.CAPR-13-0065  0.8
2013 Butler AE, Campbell-Thompson M, Gurlo T, Dawson DW, Atkinson M, Butler PC. Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors. Diabetes. 62: 2595-604. PMID 23524641 DOI: 10.2337/db12-1686  0.8
2013 Nguyen Kovochich A, Arensman M, Lay AR, Rao NP, Donahue T, Li X, French SW, Dawson DW. HOXB7 promotes invasion and predicts survival in pancreatic adenocarcinoma. Cancer. 119: 529-39. PMID 22914903 DOI: 10.1002/cncr.27725  0.8
2012 Mann KM, Ward JM, Yew CC, Kovochich A, Dawson DW, Black MA, Brett BT, Sheetz TE, Dupuy AJ, Chang DK, Biankin AV, Waddell N, Kassahn KS, Grimmond SM, et al. Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proceedings of the National Academy of Sciences of the United States of America. 109: 5934-41. PMID 22421440 DOI: 10.1073/pnas.1202490109  0.8
2012 Donahue TR, Tran LM, Hill R, Li Y, Kovochich A, Calvopina JH, Patel SG, Wu N, Hindoyan A, Farrell JJ, Li X, Dawson DW, Wu H. Integrative survival-based molecular profiling of human pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 1352-63. PMID 22261810 DOI: 10.1158/1078-0432.CCR-11-1539  0.8
2012 Biechele TL, Kulikauskas RM, Toroni RA, Lucero OM, Swift RD, James RG, Robin NC, Dawson DW, Moon RT, Chien AJ. Wnt/β-catenin signaling and AXIN1 regulate apoptosis triggered by inhibition of the mutant kinase BRAFV600E in human melanoma. Science Signaling. 5: ra3. PMID 22234612 DOI: 10.1126/scisignal.2002274  0.8
2012 Camp ND, James RG, Dawson DW, Yan F, Davison JM, Houck SA, Tang X, Zheng N, Major MB, Moon RT. Wilms tumor gene on X chromosome (WTX) inhibits degradation of NRF2 protein through competitive binding to KEAP1 protein. The Journal of Biological Chemistry. 287: 6539-50. PMID 22215675 DOI: 10.1074/jbc.M111.316471  0.8
2012 White BD, Chien AJ, Dawson DW. Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers. Gastroenterology. 142: 219-32. PMID 22155636 DOI: 10.1053/j.gastro.2011.12.001  0.8
2011 Donahue TR, Dawson DW. Nodal/Activin signaling: a novel target for pancreatic cancer stem cell therapy. Cell Stem Cell. 9: 383-4. PMID 22056131 DOI: 10.1016/j.stem.2011.10.006  0.8
2011 Li A, King J, Moro A, Sugi MD, Dawson DW, Kaplan J, Li G, Lu X, Strieter RM, Burdick M, Go VL, Reber HA, Eibl G, Hines OJ. Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer. The American Journal of Pathology. 178: 1340-9. PMID 21356384 DOI: 10.1016/j.ajpath.2010.11.058  0.8
2011 Takahashi H, Li A, Dawson DW, Hines OJ, Reber HA, Eibl G. Cyclooxygenase-2 confers growth advantage to syngeneic pancreatic cancer cells. Pancreas. 40: 453-9. PMID 21343834 DOI: 10.1097/MPA.0b013e31820b9733  0.8
2011 Angst E, Dawson DW, Stroka D, Gloor B, Park J, Candinas D, Reber HA, Hines OJ, Eibl G. N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo. Surgery. 149: 614-24. PMID 21236457 DOI: 10.1016/j.surg.2010.11.002  0.8
2010 Hill R, Calvopina JH, Kim C, Wang Y, Dawson DW, Donahue TR, Dry S, Wu H. PTEN loss accelerates KrasG12D-induced pancreatic cancer development. Cancer Research. 70: 7114-24. PMID 20807812 DOI: 10.1158/0008-5472.CAN-10-1649  0.8
2010 Lucero OM, Dawson DW, Moon RT, Chien AJ. A re-evaluation of the "oncogenic" nature of Wnt/beta-catenin signaling in melanoma and other cancers. Current Oncology Reports. 12: 314-8. PMID 20603725 DOI: 10.1007/s11912-010-0114-3  0.8
2010 Zhang L, Angst E, Park JL, Moro A, Dawson DW, Reber HA, Eibl G, Hines OJ, Go VL, Lu QY. Quercetin aglycone is bioavailable in murine pancreas and pancreatic xenografts. Journal of Agricultural and Food Chemistry. 58: 7252-7. PMID 20499918 DOI: 10.1021/jf101192k  0.8
2010 Angst E, Dawson DW, Nguyen A, Park J, Go VL, Reber HA, Hines OJ, Eibl G. Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells. Pancreas. 39: 675-9. PMID 20173668 DOI: 10.1097/MPA.0b013e3181c8b476  0.8
2010 Manuyakorn A, Paulus R, Farrell J, Dawson NA, Tze S, Cheung-Lau G, Hines OJ, Reber H, Seligson DB, Horvath S, Kurdistani SK, Guha C, Dawson DW. Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1358-65. PMID 20142597 DOI: 10.1200/JCO.2009.24.5639  0.8
2010 Pham H, Chen M, Li A, King J, Angst E, Dawson DW, Park J, Reber HA, Hines OJ, Eibl G. Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors. Pancreas. 39: 332-9. PMID 19820419 DOI: 10.1097/MPA.0b013e3181baecbe  0.8
2009 Balatoni CE, Dawson DW, Suh J, Sherman MH, Sanders G, Hong JS, Frank MJ, Malone CS, Said JW, Teitell MA. Epigenetic silencing of Stk39 in B-cell lymphoma inhibits apoptosis from genotoxic stress. The American Journal of Pathology. 175: 1653-61. PMID 19717643 DOI: 10.2353/ajpath.2009.090091  0.8
2009 Chen SS, Raval A, Johnson AJ, Hertlein E, Liu TH, Jin VX, Sherman MH, Liu SJ, Dawson DW, Williams KE, Lanasa M, Liyanarachchi S, Lin TS, Marcucci G, Pekarsky Y, et al. Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America. 106: 13433-8. PMID 19666576 DOI: 10.1073/pnas.0906455106  0.8
2009 Frank MJ, Dawson DW, Bensinger SJ, Hong JS, Knosp WM, Xu L, Balatoni CE, Allen EL, Shen RR, Bar-Sagi D, Martin GR, Teitell MA. Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. Blood. 113: 2478-87. PMID 19147787 DOI: 10.1182/blood-2008-05-156943  0.8
2008 Hasan S, Satake M, Dawson DW, Funahashi H, Angst E, Go VL, Reber HA, Hines OJ, Eibl G. Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers. Pancreas. 37: 121-7. PMID 18665070 DOI: 10.1097/MPA.0b013e31816618ba  0.8
2008 Thomas RM, Kim J, Revelo-Penafiel MP, Angel R, Dawson DW, Lowy AM. The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia. Gut. 57: 1555-60. PMID 18664506 DOI: 10.1136/gut.2007.143941  0.8
2008 Tang RS, Weinberg B, Dawson DW, Reber H, Hines OJ, Tomlinson JS, Chaudhari V, Raman S, Farrell JJ. Evaluation of the guidelines for management of pancreatic branch-duct intraductal papillary mucinous neoplasm. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 6: 815-9; quiz 719. PMID 18602036 DOI: 10.1016/j.cgh.2008.04.005  0.8
2007 Smiraglia DJ, Kazhiyur-Mannar R, Oakes CC, Wu YZ, Liang P, Ansari T, Su J, Rush LJ, Smith LT, Yu L, Liu C, Dai Z, Chen SS, Wang SH, Costello J, ... ... Dawson DW, et al. Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations. Bmc Genomics. 8: 446. PMID 18053125 DOI: 10.1186/1471-2164-8-446  0.8
2007 Pelling AE, Dawson DW, Carreon DM, Christiansen JJ, Shen RR, Teitell MA, Gimzewski JK. Distinct contributions of microtubule subtypes to cell membrane shape and stability. Nanomedicine : Nanotechnology, Biology, and Medicine. 3: 43-52. PMID 17379168 DOI: 10.1016/j.nano.2006.11.006  0.8
2007 Dawson DW, Hong JS, Shen RR, French SW, Troke JJ, Wu YZ, Chen SS, Gui D, Regelson M, Marahrens Y, Morse HC, Said J, Plass C, Teitell MA. Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas. Oncogene. 26: 4243-52. PMID 17260020 DOI: 10.1038/sj.onc.1210211  0.8
2007 French SW, Dawson DW, Chen HW, Rainey RN, Sievers SA, Balatoni CE, Wong L, Troke JJ, Nguyen MT, Koehler CM, Teitell MA. The TCL1 oncoprotein binds the RNase PH domains of the PNPase exoribonuclease without affecting its RNA degrading activity. Cancer Letters. 248: 198-210. PMID 16934922 DOI: 10.1016/j.canlet.2006.07.006  0.8
2006 Chen HW, Rainey RN, Balatoni CE, Dawson DW, Troke JJ, Wasiak S, Hong JS, McBride HM, Koehler CM, Teitell MA, French SW. Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis Molecular and Cellular Biology. 26: 8475-8487. PMID 16966381 DOI: 10.1128/MCB.01002-06  0.8
2005 Hoyer KK, Herling M, Bagrintseva K, Dawson DW, French SW, Renard M, Weinger JG, Jones D, Teitell MA. T cell leukemia-1 modulates TCR signal strength and IFN-gamma levels through phosphatidylinositol 3-kinase and protein kinase C pathway activation. Journal of Immunology (Baltimore, Md. : 1950). 175: 864-73. PMID 16002684  0.8
2003 Goodarzi MO, Dawson DW, Li X, Lei Z, Shintaku P, Rao CV, Van Herle AJ. Virilization in bilateral macronodular adrenal hyperplasia controlled by luteinizing hormone. The Journal of Clinical Endocrinology and Metabolism. 88: 73-7. PMID 12519832 DOI: 10.1210/jc.2002-021292  0.8
2002 French SW, Dawson DW, Miner MD, Doerr JR, Malone CS, Wall R, Teitell MA. DNA methylation profiling: a new tool for evaluating hematologic malignancies. Clinical Immunology (Orlando, Fla.). 103: 217-30. PMID 12173296 DOI: 10.1006/clim.2002.5186  0.8
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