Jason D. Weber - Publications

Affiliations: 
Biology & Biomedical Sciences (Molecular Cell Biology) Washington University, Saint Louis, St. Louis, MO 
Area:
Molecular Biology

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zuo C, Baer JM, Knolhoff BL, Belle JI, Liu X, Alarcon De La Lastra A, Fu C, Hogg GD, Kingston NL, Breden MA, Dodhiawala PB, Zhou DC, Lander VE, James CA, Ding L, ... ... Weber JD, et al. Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy. The Journal of Experimental Medicine. 220. PMID 36951731 DOI: 10.1084/jem.20212062  0.339
2023 Cottrell KA, Ryu S, Torres LS, Schab AM, Weber JD. Induction of viral mimicry upon loss of DHX9 and ADAR1 in breast cancer cells. Biorxiv : the Preprint Server For Biology. PMID 36909617 DOI: 10.1101/2023.02.27.530307  0.338
2022 Kung CP, Weber JD. It's Getting Complicated-A Fresh Look at p53-MDM2-ARF Triangle in Tumorigenesis and Cancer Therapy. Frontiers in Cell and Developmental Biology. 10: 818744. PMID 35155432 DOI: 10.3389/fcell.2022.818744  0.315
2020 Cottrell KA, Chiou RC, Weber JD. Upregulation of 5'-terminal oligopyrimidine mRNA translation upon loss of the ARF tumor suppressor. Scientific Reports. 10: 22276. PMID 33335292 DOI: 10.1038/s41598-020-79379-8  0.487
2020 Kung C, Kuzmicki CE, Bross EA, Ryu S, Freeman E, Sabloak T, Bramel ER, Maggi LB, Weber JD. Abstract P4-08-03: Tumor suppressors p53 and ARF control ADAR1-driven tumorigenicity in triple negative breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-08-03  0.487
2019 Wang J, Feng W, Yuan Z, Weber JD, Zhang Y. DHX33 interacts with AP-2β to regulate Bcl-2 gene expression and promote cancer cell survival. Molecular and Cellular Biology. PMID 31182639 DOI: 10.1128/Mcb.00017-19  0.426
2019 Yao CH, Wang R, Wang Y, Kung CP, Weber JD, Patti GJ. Mitochondrial fusion supports increased oxidative phosphorylation during cell proliferation. Elife. 8. PMID 30694178 DOI: 10.7554/Elife.41351  0.333
2019 Kung C, Bross E, Bramel E, Freeman E, Sabloak T, Kuzmicki C, Benjamin M, Maggi L, Weber J. 3174 Tumor suppressors p53 and ARF control oncogenic potential of triple-negative breast cancer cells by regulating RNA editing enzyme ADAR1 Journal of Clinical and Translational Science. 3: 25-26. DOI: 10.1017/cts.2019.61  0.407
2018 Kung CP, Maggi LB, Weber JD. The Role of RNA Editing in Cancer Development and Metabolic Disorders. Frontiers in Endocrinology. 9: 762. PMID 30619092 DOI: 10.3389/Fendo.2018.00762  0.347
2018 Wagner AH, Devarakonda S, Skidmore ZL, Krysiak K, Ramu A, Trani L, Kunisaki J, Masood A, Waqar SN, Spies NC, Morgensztern D, Waligorski J, Ponce J, Fulton RS, Maggi LB, ... Weber JD, et al. Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer. Nature Communications. 9: 3787. PMID 30224629 DOI: 10.1038/S41467-018-06162-9  0.383
2018 Yao C, Wang R, Wang Y, Kung C, Weber JD, Patti GJ. Author response: Mitochondrial fusion supports increased oxidative phosphorylation during cell proliferation Elife. DOI: 10.7554/Elife.41351.032  0.308
2018 Kung C, Bross EA, Kuzmicki CE, Benjamin M, Maggi LB, Weber JD. 2213 Tumor suppressors p53 and ARF control oncogenic potential of triple-negative breast cancer cells by regulating RNA editing enzyme ADAR1 Journal of Clinical and Translational Science. 2: 34-34. DOI: 10.1017/cts.2018.143  0.415
2017 Mahajan N, Wu HJ, Bennett RL, Troche C, Licht JD, Weber JD, Maggi LB, Tomasson MH. Sabotaging of the oxidative stress response by an oncogenic noncoding RNA. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 31: 482-490. PMID 28148777 DOI: 10.1096/Fj.201600654R  0.427
2016 Yuan B, Wang X, Fan C, You J, Liu Y, Weber JD, Zhongand H, Zhang Y. DHX33 transcriptionally controls genes involved in cell cycle. Molecular and Cellular Biology. PMID 27601587 DOI: 10.1128/Mcb.00314-16  0.485
2015 Zhang Y, You J, Wang X, Weber J. The DHX33 RNA helicase promotes mRNA translation initiation. Molecular and Cellular Biology. PMID 26100019 DOI: 10.1128/Mcb.00315-15  0.405
2015 Maggi LB, Weber JD. Targeting PTEN-defined breast cancers with a one-two punch. Breast Cancer Research : Bcr. 17: 51. PMID 25888162 DOI: 10.1186/S13058-015-0566-3  0.335
2015 Mahajan N, Maggi LB, Tomasson MH, Weber JD. Abstract LB-298: The multiple-myeloma associated snoRNA, ACA11 increases oxidative stress and cell proliferation Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-298  0.428
2014 Zhang Y, Baysac KC, Yee LF, Saporita AJ, Weber JD. Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers. Breast Cancer Research : Bcr. 16: 449. PMID 25260534 DOI: 10.1186/S13058-014-0449-Z  0.374
2014 Govindan R, Weber J. TP53 mutations and lung cancer: not all mutations are created equal. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4419-21. PMID 24916693 DOI: 10.1158/1078-0432.Ccr-14-0899  0.31
2014 Forys JT, Kuzmicki CE, Saporita AJ, Winkeler CL, Maggi LB, Weber JD. ARF and p53 coordinate tumor suppression of an oncogenic IFN-β-STAT1-ISG15 signaling axis. Cell Reports. 7: 514-26. PMID 24726362 DOI: 10.1016/J.Celrep.2014.03.026  0.781
2014 Maggi LB, Winkeler CL, Miceli AP, Apicelli AJ, Brady SN, Kuchenreuther MJ, Weber JD. ARF tumor suppression in the nucleolus. Biochimica Et Biophysica Acta. 1842: 831-9. PMID 24525025 DOI: 10.1016/J.Bbadis.2014.01.016  0.703
2014 Kuchenreuther MJ, Weber JD. The ARF tumor-suppressor controls Drosha translation to prevent Ras-driven transformation. Oncogene. 33: 300-7. PMID 23318441 DOI: 10.1038/Onc.2012.601  0.81
2013 Zhong H, Sanchez C, Spitrzer D, Plambeck-Suess S, Gibbs J, Hawkins WG, Denardo D, Gao F, Pufahl RA, Lockhart AC, Xu M, Linehan D, Weber J, Wang-Gillam A. Synergistic effects of concurrent blockade of PI3K and MEK pathways in pancreatic cancer preclinical models. Plos One. 8: e77243. PMID 24130864 DOI: 10.1371/Journal.Pone.0077243  0.438
2013 Chang CH, Curtis JD, Maggi LB, Faubert B, Villarino AV, O'Sullivan D, Huang SC, van der Windt GJ, Blagih J, Qiu J, Weber JD, Pearce EJ, Jones RG, Pearce EL. Posttranscriptional control of T cell effector function by aerobic glycolysis. Cell. 153: 1239-51. PMID 23746840 DOI: 10.1016/J.Cell.2013.05.016  0.378
2013 Zhang Y, Saporita AJ, Weber JD. P19ARF and RasV¹² offer opposing regulation of DHX33 translation to dictate tumor cell fate. Molecular and Cellular Biology. 33: 1594-607. PMID 23401854 DOI: 10.1128/Mcb.01220-12  0.469
2012 Craig EA, Weber JD, Spiegelman VS. Involvement of the mRNA binding protein CRD-BP in the regulation of metastatic melanoma cell proliferation and invasion by hypoxia. Journal of Cell Science. 125: 5950-4. PMID 23038779 DOI: 10.1242/jcs.115204  0.338
2012 Winkeler CL, Kladney RD, Maggi LB, Weber JD. Cathepsin K-Cre causes unexpected germline deletion of genes in mice. Plos One. 7: e42005. PMID 22860046 DOI: 10.1371/Journal.Pone.0042005  0.753
2012 Xu Z, Joshi N, Agarwal A, Dahiya S, Bittner P, Smith E, Taylor S, Piwnica-Worms D, Weber J, Leonard JR. Knocking down nucleolin expression in gliomas inhibits tumor growth and induces cell cycle arrest. Journal of Neuro-Oncology. 108: 59-67. PMID 22382782 DOI: 10.1007/S11060-012-0827-2  0.436
2012 Weber JD, Gutmann DH. Deconvoluting mTOR biology. Cell Cycle (Georgetown, Tex.). 11: 236-48. PMID 22214661 DOI: 10.4161/Cc.11.2.19022  0.44
2012 Miceli AP, Saporita AJ, Weber JD. Hypergrowth mTORC1 signals translationally activate the ARF tumor suppressor checkpoint. Molecular and Cellular Biology. 32: 348-64. PMID 22064482 DOI: 10.1128/Mcb.06030-11  0.832
2012 Zhang Y, Weber JD. Abstract 2160: Regulation of DHX33 during oncogenic stress and its crucial role in Ras-initiated tumor formation Cancer Research. 72: 2160-2160. DOI: 10.1158/1538-7445.Am2012-2160  0.428
2011 Wang J, Zhang K, Grabowska D, Li A, Dong Y, Day R, Humphrey P, Lewis J, Kladney RD, Arbeit JM, Weber JD, Chung CH, Michel LS. Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma. Molecular Cancer Research : McR. 9: 1686-95. PMID 21970857 DOI: 10.1158/1541-7786.Mcr-11-0241  0.467
2011 Saporita AJ, Chang HC, Winkeler CL, Apicelli AJ, Kladney RD, Wang J, Townsend RR, Michel LS, Weber JD. RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis. Cancer Research. 71: 6708-17. PMID 21937682 DOI: 10.1158/0008-5472.Can-11-1472  0.82
2011 Zhang Y, Forys JT, Miceli AP, Gwinn AS, Weber JD. Identification of DHX33 as a mediator of rRNA synthesis and cell growth. Molecular and Cellular Biology. 31: 4676-91. PMID 21930779 DOI: 10.1128/Mcb.05832-11  0.777
2011 Olanich ME, Moss BL, Piwnica-Worms D, Townsend RR, Weber JD. Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation. Oncogene. 30: 77-86. PMID 20802533 DOI: 10.1038/Onc.2010.404  0.82
2011 Forys JT, Kladney RD, Weber JD. Abstract A40: Investigating the functional response of the ARF tumor suppressor to acute p53 loss Cancer Research. 71. DOI: 10.1158/1538-7445.Fbcr11-A40  0.815
2010 Rauch DA, Hurchla MA, Harding JC, Deng H, Shea LK, Eagleton MC, Niewiesk S, Lairmore MD, Piwnica-Worms D, Rosol TJ, Weber JD, Ratner L, Weilbaecher KN. The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice. Plos One. 5: e15755. PMID 21209895 DOI: 10.1371/Journal.Pone.0015755  0.413
2010 Kladney RD, Cardiff RD, Kwiatkowski DJ, Chiang GG, Weber JD, Arbeit JM, Lu ZH. Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice. Cancer Research. 70: 8937-47. PMID 20940396 DOI: 10.1158/0008-5472.Can-10-1646  0.348
2010 Dong Y, Li A, Wang J, Weber JD, Michel LS. Synthetic lethality through combined Notch-epidermal growth factor receptor pathway inhibition in basal-like breast cancer. Cancer Research. 70: 5465-74. PMID 20570903 DOI: 10.1158/0008-5472.Can-10-0173  0.409
2010 Abella N, Brun S, Calvo M, Tapia O, Weber JD, Berciano MT, Lafarga M, Bachs O, Agell N. Nucleolar disruption ensures nuclear accumulation of p21 upon DNA damage. Traffic (Copenhagen, Denmark). 11: 743-55. PMID 20331843 DOI: 10.1111/J.1600-0854.2010.01063.X  0.371
2009 Brady SN, Maggi LB, Winkeler CL, Toso EA, Gwinn AS, Pelletier CL, Weber JD. Nucleophosmin protein expression level, but not threonine 198 phosphorylation, is essential in growth and proliferation. Oncogene. 28: 3209-20. PMID 19561638 DOI: 10.1038/Onc.2009.178  0.767
2009 Crowder RJ, Phommaly C, Tao Y, Hoog J, Luo J, Perou CM, Parker JS, Miller MA, Huntsman DG, Lin L, Snider J, Davies SR, Olson JA, Watson MA, Saporita A, ... Weber JD, et al. PIK3CA and PIK3CB inhibition produce synthetic lethality when combined with estrogen deprivation in estrogen receptor-positive breast cancer. Cancer Research. 69: 3955-62. PMID 19366795 DOI: 10.1158/0008-5472.Can-08-4450  0.334
2008 Maggi LB, Kuchenruether M, Dadey DY, Schwope RM, Grisendi S, Townsend RR, Pandolfi PP, Weber JD. Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. Molecular and Cellular Biology. 28: 7050-65. PMID 18809582 DOI: 10.1128/Mcb.01548-07  0.515
2008 Apicelli AJ, Maggi LB, Hirbe AC, Miceli AP, Olanich ME, Schulte-Winkeler CL, Saporita AJ, Kuchenreuther M, Sanchez J, Weilbaecher K, Weber JD. A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and function. Molecular and Cellular Biology. 28: 1068-80. PMID 18070929 DOI: 10.1128/Mcb.00484-07  0.776
2007 Saporita AJ, Maggi LB, Apicelli AJ, Weber JD. Therapeutic targets in the ARF tumor suppressor pathway. Current Medicinal Chemistry. 14: 1815-27. PMID 17627519 DOI: 10.2174/092986707781058869  0.809
2007 Wong S, Weber JD. Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1. The Biochemical Journal. 407: 451-60. PMID 17620057 DOI: 10.1042/Bj20070151  0.482
2007 Sandsmark DK, Zhang H, Hegedus B, Pelletier CL, Weber JD, Gutmann DH. Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes. Cancer Research. 67: 4790-9. PMID 17510408 DOI: 10.1158/0008-5472.Can-06-4470  0.723
2007 Sandsmark DK, Pelletier C, Weber JD, Gutmann DH. Mammalian target of rapamycin: master regulator of cell growth in the nervous system. Histology and Histopathology. 22: 895-903. PMID 17503347 DOI: 10.14670/Hh-22.895  0.742
2007 Takeshita S, Faccio R, Chappel J, Zheng L, Feng X, Weber JD, Teitelbaum SL, Ross FP. c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages. The Journal of Biological Chemistry. 282: 18980-90. PMID 17420255 DOI: 10.1074/Jbc.M610938200  0.341
2007 Pelletier CL, Maggi LB, Brady SN, Scheidenhelm DK, Gutmann DH, Weber JD. TSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translation. Cancer Research. 67: 1609-17. PMID 17308101 DOI: 10.1158/0008-5472.Can-06-2875  0.809
2006 Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, Rustgi A, Fuchs SY, Diehl JA. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex. Molecular Cell. 24: 355-66. PMID 17081987 DOI: 10.1016/J.Molcel.2006.09.007  0.344
2006 Yu Y, Maggi LB, Brady SN, Apicelli AJ, Dai MS, Lu H, Weber JD. Nucleophosmin is essential for ribosomal protein L5 nuclear export. Molecular and Cellular Biology. 26: 3798-809. PMID 16648475 DOI: 10.1128/Mcb.26.10.3798-3809.2006  0.793
2006 Keller PC, Tomita T, Hayashi I, Chandu D, Weber JD, Cistola DP, Kopan R. A faster migrating variant masquerades as NICD when performing in vitro gamma-secretase assays with bacterially expressed Notch substrates. Biochemistry. 45: 5351-8. PMID 16618124 DOI: 10.1021/Bi052228A  0.308
2005 Maggi LB, Weber JD. Nucleolar adaptation in human cancer. Cancer Investigation. 23: 599-608. PMID 16305988 DOI: 10.1080/07357900500283085  0.393
2005 Dasgupta B, Yi Y, Hegedus B, Weber JD, Gutmann DH. Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma. Cancer Research. 65: 9843-50. PMID 16267007 DOI: 10.1158/0008-5472.Can-05-1842  0.487
2005 Dasgupta B, Yi Y, Chen DY, Weber JD, Gutmann DH. Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors. Cancer Research. 65: 2755-60. PMID 15805275 DOI: 10.1158/0008-5472.Can-04-4058  0.463
2004 Brady SN, Yu Y, Maggi LB, Weber JD. ARF impedes NPM/B23 shuttling in an Mdm2-sensitive tumor suppressor pathway. Molecular and Cellular Biology. 24: 9327-38. PMID 15485902 DOI: 10.1128/Mcb.24.21.9327-9338.2004  0.841
2003 Weber JD, Zambetti GP. Renewing the debate over the p53 apoptotic response Cell Death and Differentiation. 10: 409-412. PMID 12719717 DOI: 10.1038/Sj.Cdd.4401226  0.374
2001 Bothner B, Lewis WS, DiGiammarino EL, Weber JD, Bothner SJ, Kriwacki RW. Defining the molecular basis of Arf and Hdm2 interactions. Journal of Molecular Biology. 314: 263-77. PMID 11718560 DOI: 10.1006/Jmbi.2001.5110  0.374
2001 DiGiammarino EL, Filippov I, Weber JD, Bothner B, Kriwacki RW. Solution structure of the p53 regulatory domain of the p19Arf tumor suppressor protein. Biochemistry. 40: 2379-86. PMID 11327858 DOI: 10.1021/Bi0024005  0.448
2000 Weber JD, Jeffers JR, Rehg JE, Randle DH, Lozano G, Roussel MF, Sherr CJ, Zambetti GP. p53-independent functions of the p19(ARF) tumor suppressor. Genes & Development. 14: 2358-65. PMID 10995391 DOI: 10.1101/Gad.827300  0.485
2000 Groth A, Weber JD, Willumsen BM, Sherr CJ, Roussel MF. Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases. The Journal of Biological Chemistry. 275: 27473-80. PMID 10842176 DOI: 10.1074/Jbc.M003417200  0.45
2000 Weber JD, Kuo ML, Bothner B, DiGiammarino EL, Kriwacki RW, Roussel MF, Sherr CJ. Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex. Molecular and Cellular Biology. 20: 2517-28. PMID 10713175 DOI: 10.1128/Mcb.20.7.2517-2528.2000  0.45
2000 Sherr CJ, Weber JD. The ARF/p53 pathway. Current Opinion in Genetics & Development. 10: 94-9. PMID 10679383 DOI: 10.1016/S0959-437X(99)00038-6  0.467
1999 Weber JD, Taylor LJ, Roussel MF, Sherr CJ, Bar-Sagi D. Nucleolar Arf sequesters Mdm2 and activates p53. Nature Cell Biology. 1: 20-6. PMID 10559859 DOI: 10.1038/8991  0.432
1999 Eischen CM, Weber JD, Roussel MF, Sherr CJ, Cleveland JL. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes & Development. 13: 2658-69. PMID 10541552 DOI: 10.1101/Gad.13.20.2658  0.502
1998 Kamijo T, Weber JD, Zambetti G, Zindy F, Roussel MF, Sherr CJ. Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 95: 8292-7. PMID 9653180 DOI: 10.1073/Pnas.95.14.8292  0.447
1998 Weber JD, Hu W, Jefcoat SC, Raben DM, Baldassare JJ. Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27. The Journal of Biological Chemistry. 272: 32966-71. PMID 9407076 DOI: 10.1074/Jbc.272.52.32966  0.415
1997 Poulos JE, Weber JD, Bellezzo JM, Di Bisceglie AM, Britton RS, Bacon BR, Baldassare JJ. Fibronectin and cytokines increase JNK, ERK, AP-1 activity, and transin gene expression in rat hepatic stellate cells. The American Journal of Physiology. 273: G804-11. PMID 9357821 DOI: 10.1152/Ajpgi.1997.273.4.G804  0.321
1997 Weber JD, Raben DM, Phillips PJ, Baldassare JJ. Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase. The Biochemical Journal. 61-8. PMID 9337851 DOI: 10.1042/Bj3260061  0.384
1997 Weber JD, Cheng J, Raben DM, Gardner A, Baldassare JJ. Ablation of Goalpha overrides G1 restriction point control through Ras/ERK/cyclin D1-CDK activities. The Journal of Biological Chemistry. 272: 17320-6. PMID 9211869 DOI: 10.1074/Jbc.272.28.17320  0.446
1997 Cheng J, Weber JD, Baldassare JJ, Raben DM. Ablation of Go alpha-subunit results in a transformed phenotype and constitutively active phosphatidylcholine-specific phospholipase C. The Journal of Biological Chemistry. 272: 17312-9. PMID 9211868 DOI: 10.1074/Jbc.272.28.17312  0.449
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