Year |
Citation |
Score |
2023 |
Ou M, Cho HY, Fu J, Thein TZ, Wang W, Swenson SD, Minea RO, Stathopoulos A, Schönthal AH, Hofman FM, Tang L, Chen TC. Inhibition of autophagy and induction of glioblastoma cell death by NEO214, a perillyl alcohol-rolipram conjugate. Autophagy. 1-20. PMID 37545052 DOI: 10.1080/15548627.2023.2242696 |
0.423 |
|
2020 |
Minea RO, Duc TC, Swenson SD, Cho HY, Huang M, Hartman H, Hofman FM, Schönthal AH, Chen TC. Developing a clinically relevant radiosensitizer for temozolomide-resistant gliomas. Plos One. 15: e0238238. PMID 32881880 DOI: 10.1371/Journal.Pone.0238238 |
0.371 |
|
2019 |
Marín-Ramos NI, Pérez-Hernández M, Tam A, Swenson SD, Cho HY, Thein TZ, Hofman FM, Chen TC. Inhibition of motility by NEO100 through the calpain-1/RhoA pathway. Journal of Neurosurgery. 1-12. PMID 31419797 DOI: 10.3171/2019.5.JNS19798 |
0.506 |
|
2019 |
Wang W, Swenson S, Cho HY, Hofman FM, Schönthal AH, Chen TC. Efficient brain targeting and therapeutic intracranial activity of bortezomib through intranasal co-delivery with NEO100 in rodent glioblastoma models. Journal of Neurosurgery. 1-9. PMID 30875688 DOI: 10.3171/2018.11.Jns181161 |
0.33 |
|
2019 |
Peng L, Fu J, Wang W, Hofman FM, Chen TC, Chen L. Distribution of cancer stem cells in two human brain gliomas. Oncology Letters. 17: 2123-2130. PMID 30719107 DOI: 10.3892/ol.2018.9824 |
0.494 |
|
2019 |
Cho HY, Thein TZ, Wang W, Swenson SD, Fayngor RA, Ou M, Marín-Ramos NI, Schönthal AH, Hofman FM, Chen TC. The Rolipram-Perillyl Alcohol Conjugate (NEO214) Is A Mediator Of Cell Death Through The Death Receptor Pathway. Molecular Cancer Therapeutics. PMID 30647121 DOI: 10.1158/1535-7163.Mct-18-0465 |
0.533 |
|
2018 |
Swenson S, Silva-Hirschberg C, Wang W, Singh A, Hofman FM, Chen KL, Schönthal AH, Chen TC. NEO412: A temozolomide analog with transdermal activity in melanoma and . Oncotarget. 9: 37026-37041. PMID 30651933 DOI: 10.18632/Oncotarget.26443 |
0.401 |
|
2018 |
Marín-Ramos NI, Jhaveri N, Thein TZ, Fayngor RA, Chen TC, Hofman FM. NEO212, a conjugate of temozolomide and perillyl alcohol, blocks the endothelial-to-mesenchymal transition in tumor-associated brain endothelial cells in glioblastoma. Cancer Letters. PMID 30392789 DOI: 10.1016/j.canlet.2018.10.034 |
0.494 |
|
2018 |
Chen TC, Chan N, Minea RO, Hartman H, Hofman FM, Schönthal AH. Rare Stochastic Expression of O6-Methylguanine- DNA Methyltransferase (MGMT) in MGMT-Negative Melanoma Cells Determines Immediate Emergence of Drug-Resistant Populations upon Treatment with Temozolomide In Vitro and In Vivo. Cancers. 10. PMID 30274152 DOI: 10.3390/Cancers10100362 |
0.438 |
|
2018 |
Bota DA, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FP, Schönthal AH, Hofman FM, Chen TC, Zidovetzki R, Pretto C, Strik A, Schijns VE, Stathopoulos A. Phase II study of ERC1671 plus bevacizumab versus bevacizumab plus placebo in recurrent glioblastoma: interim results and correlations with CD4 T-lymphocyte counts. Cns Oncology. PMID 30157683 DOI: 10.2217/Cns-2018-0009 |
0.406 |
|
2018 |
Schijns VEJC, Pretto C, Strik AM, Gloudemans-Rijkers R, Deviller L, Pierre D, Chung J, Dandekar M, Carrillo JA, Kong XT, Fu BD, Hsu FPK, Hofman FM, Chen TC, Zidovetzki R, et al. Therapeutic Immunization against Glioblastoma. International Journal of Molecular Sciences. 19. PMID 30150597 DOI: 10.3390/Ijms19092540 |
0.482 |
|
2018 |
Marín-Ramos NI, Thein TZ, Cho HY, Swenson SD, Wang W, Schönthal AH, Chen TC, Hofman FM. NEO212 Inhibits Migration and Invasion of Glioma Stem Cells. Molecular Cancer Therapeutics. PMID 29440289 DOI: 10.1158/1535-7163.Mct-17-0591 |
0.469 |
|
2018 |
Chen T, Wang W, Hofman F, Schonthal A. CADD-56. INTRA-ARTERIAL NEO100 TRANSIENTLY OPENS THE BLOOD BRAIN BARRIER Neuro-Oncology. 20: vi283-vi283. DOI: 10.1093/Neuonc/Noy148.1181 |
0.315 |
|
2017 |
Chen TC, Yu J, Nigjeh EN, Wang W, Myint PT, Zandi E, Hofman FM, Schönthal AH. A Perillyl Alcohol-Conjugated Analog of 3-Bromopyruvate Without Cellular Uptake Dependency on Monocarboxylate Transporter 1 and With Activity in 3-BP-Resistant Tumor Cells. Cancer Letters. PMID 28450161 DOI: 10.1016/J.Canlet.2017.04.015 |
0.428 |
|
2017 |
Wang W, Cho HY, Rosenstein-Sisson R, Marín Ramos NI, Price R, Hurth K, Schönthal AH, Hofman FM, Chen TC. Intratumoral delivery of bortezomib: impact on survival in an intracranial glioma tumor model. Journal of Neurosurgery. 1-6. PMID 28409734 DOI: 10.3171/2016.11.Jns161212 |
0.543 |
|
2017 |
Eliahu K, Hofman F, Giannotta S. A Systematic Review of Cerebral Arteriovenous Malformation Management International Journal of Medical Students. 5: 74-80. DOI: 10.5195/Ijms.2017.13 |
0.309 |
|
2016 |
Rosa AI, Grade S, Santos SD, Bernardino L, Chen TC, Relvas J, Hofman FM, Agasse F. Heterocellular Contacts with Mouse Brain Endothelial Cells Via Laminin and α6β1 Integrin Sustain Subventricular Zone (SVZ) Stem/Progenitor Cells Properties. Frontiers in Cellular Neuroscience. 10: 284. PMID 28018177 DOI: 10.3389/fncel.2016.00284 |
0.338 |
|
2016 |
Kushal S, Wang W, Vaikari VP, Kota R, Chen K, Yeh TS, Jhaveri N, Groshen SL, Olenyuk BZ, Chen TC, Hofman FM, Shih JC. Monoamine oxidase A (MAO A) inhibitors decrease glioma progression. Oncotarget. PMID 26871599 DOI: 10.18632/Oncotarget.7283 |
0.493 |
|
2016 |
Dong H, Zou M, Bhatia A, Jayaprakash P, Hofman F, Ying Q, Chen M, Woodley DT, Li W. Breast Cancer MDA-MB-231 Cells Use Secreted Heat Shock Protein-90alpha (Hsp90α) to Survive a Hostile Hypoxic Environment. Scientific Reports. 6: 20605. PMID 26846992 DOI: 10.1038/Srep20605 |
0.39 |
|
2015 |
Jhaveri N, Agasse F, Armstrong D, Peng L, Commins D, Wang W, Rosenstein-Sisson R, Vaikari VP, Santiago SV, Santos T, Chen L, Schönthal AH, Chen TC, Hofman FM. A novel drug conjugate targeting proneural and mesenchymal subtypes of patient-derived glioma cancer stem cells. Cancer Letters. PMID 26683773 DOI: 10.1016/J.Canlet.2015.11.040 |
0.525 |
|
2015 |
Chen TC, Cho HY, Wang W, Wetzel SJ, Singh A, Nguyen J, Hofman FM, Schönthal AH. Chemotherapeutic effect of a novel temozolomide analog on nasopharyngeal carcinoma in vitro and in vivo. Journal of Biomedical Science. 22: 71. PMID 26282951 DOI: 10.1186/S12929-015-0175-6 |
0.443 |
|
2015 |
Schijns VE, Pretto C, Devillers L, Pierre D, Hofman FM, Chen TC, Mespouille P, Hantos P, Glorieux P, Bota DA, Stathopoulos A. First clinical results of a personalized immunotherapeutic vaccine against recurrent, incompletely resected, treatment-resistant glioblastoma multiforme (GBM) tumors, based on combined allo- and auto-immune tumor reactivity. Vaccine. 33: 2690-6. PMID 25865468 DOI: 10.1016/J.Vaccine.2015.03.095 |
0.301 |
|
2015 |
Wang W, Sivakumar W, Torres S, Jhaveri N, Vaikari VP, Gong A, Howard A, Golden EB, Louie SG, Schönthal AH, Hofman FM, Chen TC. Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals. Neurosurgical Focus. 38: E8. PMID 25727230 DOI: 10.3171/2015.1.Focus14743 |
0.442 |
|
2015 |
Chen TC, Cho HY, Wang W, Nguyen J, Jhaveri N, Rosenstein-Sisson R, Hofman FM, Schönthal AH. A novel temozolomide analog, NEO212, with enhanced activity against MGMT-positive melanoma in vitro and in vivo. Cancer Letters. 358: 144-51. PMID 25524552 DOI: 10.1016/J.Canlet.2014.12.021 |
0.462 |
|
2015 |
Huang TT, Parab S, Burnett R, Diago O, Ostertag D, Hofman FM, Espinoza FL, Martin B, Ibañez CE, Kasahara N, Gruber HE, Pertschuk D, Jolly DJ, Robbins JM. Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model. Human Gene Therapy. 26: 82-93. PMID 25419577 DOI: 10.1089/Hum.2014.100 |
0.349 |
|
2015 |
Cho H, Wang W, Huang M, Santiago S, Schönthal AH, Hofman FM, Chen TC. ATPS-07NEO214, ROLIPRAM CONJUGATED TO PERILLYL ALCOHOL, IS A NOVEL DRUG CYTOTOXIC FOR GLIOMAS BY TARGETING THE DEATH RECEPTOR MEDIATED TRAIL PATHWAY Neuro-Oncology. 17: v19.3-v19. DOI: 10.1093/Neuonc/Nov204.07 |
0.554 |
|
2015 |
Hofman FM, Chen TC. Choroid Plexus: Structure and Function The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in Cns Development, Maintenance, and Disease Progression. 29-40. DOI: 10.1016/B978-0-12-801740-1.00003-2 |
0.305 |
|
2014 |
Jhaveri N, Chen TC, Hofman FM. Tumor vasculature and glioma stem cells: Contributions to glioma progression. Cancer Letters. PMID 25527451 DOI: 10.1016/j.canlet.2014.12.028 |
0.568 |
|
2014 |
Santos T, Fang X, Chen MT, Wang W, Ferreira R, Jhaveri N, Gundersen M, Zhou C, Pagnini P, Hofman FM, Chen TC. Sequential administration of carbon nanotubes and near-infrared radiation for the treatment of gliomas. Frontiers in Oncology. 4: 180. PMID 25077069 DOI: 10.3389/Fonc.2014.00180 |
0.447 |
|
2014 |
Cho HY, Wang W, Jhaveri N, Lee DJ, Sharma N, Dubeau L, Schönthal AH, Hofman FM, Chen TC. NEO212, temozolomide conjugated to perillyl alcohol, is a novel drug for effective treatment of a broad range of temozolomide-resistant gliomas. Molecular Cancer Therapeutics. 13: 2004-17. PMID 24994771 DOI: 10.1158/1535-7163.Mct-13-0964 |
0.412 |
|
2014 |
Peterson A, Bansal A, Hofman F, Chen TC, Zada G. A systematic review of inhaled intranasal therapy for central nervous system neoplasms: an emerging therapeutic option. Journal of Neuro-Oncology. 116: 437-46. PMID 24398618 DOI: 10.1007/S11060-013-1346-5 |
0.467 |
|
2014 |
Schijns V, Pretto C, Devillers L, Pierre D, Hofman F, Kruse C, Chen T, Oertel J, Hantos P, Bota D, Stathopoulos A. ET-54 * IMMUNOTHERAPY BASED ON TUMOR TRANSPLANT ANTIGEN RECOGNITION EMERGES AS A PROMISING STRATEGY FOR RECURRENT GLIOBLASTOMA MULTIFORME (GBM) PATIENTS Neuro-Oncology. 16: v90-v91. DOI: 10.1093/Neuonc/Nou255.51 |
0.354 |
|
2014 |
Chen TC, Schonthal AH, Hofman FM, Wang W, Cho H. NEO212: A NOVEL TEMOZOLOMIDE-PERILLYL ALCOHOL CONJUGATE EXHIBITS SUPERIOR ACTIVITY AGAINST TEMOZOLOMIDE RESISTANT GLIOMAS AND INTRACRANIAL TRIPLE NEGATIVE BREAST CANCER METASTASIS Neuro-Oncology. 16: iii35-iii36. DOI: 10.1093/Neuonc/Nou208.48 |
0.359 |
|
2013 |
Sharma N, Dong D, Louie S, Cho H, Chen T, Hofman F, Schonthal A. Abstract 1853: Reduced glucose uptake and inhibition of ATP synthase by mefloquine results in death of glioblastoma multiforme. Cancer Research. 73: 1853-1853. DOI: 10.1158/1538-7445.Am2013-1853 |
0.449 |
|
2012 |
Stathopoulos A, Pretto C, Devillers L, Pierre D, Hofman FM, Epstein AL, Farghadani H, Kruse CA, Jadus MR, Chen TC, Schijns VE. Exploring the Therapeutic Efficacy of Glioma Vaccines Based on Allo- and Syngeneic Antigens and Distinct Immunological Costimulation Activators. Journal of Clinical & Cellular Immunology. 004. PMID 24955288 DOI: 10.4172/2155-9899.S5-004 |
0.348 |
|
2012 |
Cho HY, Wang W, Jhaveri N, Torres S, Tseng J, Leong MN, Lee DJ, Goldkorn A, Xu T, Petasis NA, Louie SG, Schönthal AH, Hofman FM, Chen TC. Perillyl alcohol for the treatment of temozolomide-resistant gliomas. Molecular Cancer Therapeutics. 11: 2462-72. PMID 22933703 DOI: 10.1158/1535-7163.Mct-12-0321 |
0.403 |
|
2012 |
Stathopoulos A, Pretto C, Devillers L, Pierre D, Hofman FM, Kruse C, Jadus M, Chen TC, Schijns VE. Development of immune memory to glial brain tumors after tumor regression induced by immunotherapeutic Toll-like receptor 7/8 activation. Oncoimmunology. 1: 298-305. PMID 22737605 DOI: 10.4161/onci.19068 |
0.415 |
|
2012 |
Thomas S, Sharma N, Golden EB, Cho H, Agarwal P, Gaffney KJ, Petasis NA, Chen TC, Hofman FM, Louie SG, Schönthal AH. Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors. Cancer Letters. 325: 63-71. PMID 22664238 DOI: 10.1016/J.Canlet.2012.05.030 |
0.359 |
|
2012 |
Dandapani S, Nguyen C, Hofman F, Chen T, Lenz H, Kahn M, Hill C, Pagnini P. Potential Role of Novel Wnt Modulator ICG-001 as a Radiosensitizer in Glioblastoma Cell Lines International Journal of Radiation Oncology*Biology*Physics. 84: S698. DOI: 10.1016/J.Ijrobp.2012.07.1866 |
0.347 |
|
2011 |
Jhaveri N, Cho H, Torres S, Wang W, Schönthal AH, Petasis NA, Louie SG, Hofman FM, Chen TC. Noscapine inhibits tumor growth in TMZ-resistant gliomas. Cancer Letters. 312: 245-52. PMID 21925789 DOI: 10.1016/J.Canlet.2011.08.015 |
0.433 |
|
2011 |
Schönthal AH, Chen TC, Hofman FM, Louie SG, Petasis NA. Preclinical development of novel anti-glioma drugs targeting the endoplasmic reticulum stress response. Current Pharmaceutical Design. 17: 2428-38. PMID 21827419 DOI: 10.2174/138161211797249242 |
0.34 |
|
2011 |
Dong D, Stapleton C, Luo B, Xiong S, Ye W, Zhang Y, Jhaveri N, Zhu G, Ye R, Liu Z, Bruhn KW, Craft N, Groshen S, Hofman FM, Lee AS. A critical role for GRP78/BiP in the tumor microenvironment for neovascularization during tumor growth and metastasis. Cancer Research. 71: 2848-57. PMID 21467168 DOI: 10.1158/0008-5472.Can-10-3151 |
0.55 |
|
2011 |
Stapleton CJ, Armstrong DL, Zidovetzki R, Liu CY, Giannotta SL, Hofman FM. Thrombospondin-1 modulates the angiogenic phenotype of human cerebral arteriovenous malformation endothelial cells. Neurosurgery. 68: 1342-53; discussion . PMID 21307796 DOI: 10.1227/NEU.0b013e31820c0a68 |
0.34 |
|
2011 |
Chen TC, Wang W, Golden EB, Thomas S, Sivakumar W, Hofman FM, Louie SG, Schönthal AH. Green tea epigallocatechin gallate enhances therapeutic efficacy of temozolomide in orthotopic mouse glioblastoma models. Cancer Letters. 302: 100-8. PMID 21257259 DOI: 10.1016/J.Canlet.2010.11.008 |
0.352 |
|
2011 |
Wang W, Ghandi A, Liebes L, Louie SG, Hofman FM, Schönthal AH, Chen TC. Effective conversion of irinotecan to SN-38 after intratumoral drug delivery to an intracranial murine glioma model in vivo. Laboratory investigation. Journal of Neurosurgery. 114: 689-94. PMID 20415520 DOI: 10.3171/2010.2.Jns09719 |
0.366 |
|
2010 |
Hofman FM, Stathopoulos A, Kruse CA, Chen TC, Schijns VE. Immunotherapy of malignant gliomas using autologous and allogeneic tissue cells. Anti-Cancer Agents in Medicinal Chemistry. 10: 462-70. PMID 20879986 DOI: 10.2174/1871520611009060462 |
0.316 |
|
2010 |
Virrey JJ, Liu Z, Cho HY, Kardosh A, Golden EB, Louie SG, Gaffney KJ, Petasis NA, Schönthal AH, Chen TC, Hofman FM. Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculature. Molecular Cancer Therapeutics. 9: 631-41. PMID 20197398 DOI: 10.1158/1535-7163.Mct-09-0652 |
0.794 |
|
2010 |
Liu Z, Yuan R, Armstrong D, Louie S, Schönthal AH, Chen TC, Hofman F. Abstract 549: Interleukin-11 induces survivin expression in brain endothelial cells Cancer Research. 70: 549-549. DOI: 10.1158/1538-7445.Am10-549 |
0.654 |
|
2009 |
Virrey JJ, Golden EB, Sivakumar W, Wang W, Pen L, Schönthal AH, Hofman FM, Chen TC. Glioma-associated endothelial cells are chemoresistant to temozolomide. Journal of Neuro-Oncology. 95: 13-22. PMID 19381445 DOI: 10.1007/S11060-009-9891-7 |
0.79 |
|
2009 |
Cho HY, Thomas S, Golden EB, Gaffney KJ, Hofman FM, Chen TC, Louie SG, Petasis NA, Schönthal AH. Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress. Cancer Letters. 282: 87-97. PMID 19345476 DOI: 10.1016/J.Canlet.2009.03.007 |
0.386 |
|
2009 |
Jabbour MN, Elder JB, Samuelson CG, Khashabi S, Hofman FM, Giannotta SL, Liu CY. Aberrant angiogenic characteristics of human brain arteriovenous malformation endothelial cells. Neurosurgery. 64: 139-46; discussion 1. PMID 19145162 DOI: 10.1227/01.NEU.0000334417.56742.24 |
0.417 |
|
2008 |
Virrey JJ, Dong D, Stiles C, Patterson JB, Pen L, Ni M, Schönthal AH, Chen TC, Hofman FM, Lee AS. Stress chaperone GRP78/BiP confers chemoresistance to tumor-associated endothelial cells. Molecular Cancer Research : McR. 6: 1268-75. PMID 18708359 DOI: 10.1158/1541-7786.Mcr-08-0060 |
0.796 |
|
2008 |
Virrey JJ, Guan S, Li W, Schönthal AH, Chen TC, Hofman FM. Increased survivin expression confers chemoresistance to tumor-associated endothelial cells. The American Journal of Pathology. 173: 575-85. PMID 18599610 DOI: 10.2353/Ajpath.2008.071079 |
0.797 |
|
2008 |
Kardosh A, Golden EB, Pyrko P, Uddin J, Hofman FM, Chen TC, Louie SG, Petasis NA, Schönthal AH. Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib. Cancer Research. 68: 843-51. PMID 18245486 DOI: 10.1158/0008-5472.Can-07-5555 |
0.307 |
|
2008 |
Schönthal AH, Chen TC, Hofman FM, Louie SG, Petasis NA. Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs. Expert Opinion On Investigational Drugs. 17: 197-208. PMID 18230053 DOI: 10.1517/13543784.17.2.197 |
0.331 |
|
2008 |
Dong D, Ni M, Li J, Xiong S, Ye W, Virrey JJ, Mao C, Ye R, Wang M, Pen L, Dubeau L, Groshen S, Hofman FM, Lee AS. Critical role of the stress chaperone GRP78/BiP in tumor proliferation, survival, and tumor angiogenesis in transgene-induced mammary tumor development. Cancer Research. 68: 498-505. PMID 18199545 DOI: 10.1158/0008-5472.Can-07-2950 |
0.775 |
|
2007 |
Pyrko P, Schönthal AH, Hofman FM, Chen TC, Lee AS. The unfolded protein response regulator GRP78/BiP as a novel target for increasing chemosensitivity in malignant gliomas. Cancer Research. 67: 9809-16. PMID 17942911 DOI: 10.1158/0008-5472.Can-07-0625 |
0.472 |
|
2007 |
Kardosh A, Soriano N, Pyrko P, Liu YT, Jabbour M, Hofman FM, Schönthal AH. Reduced survivin expression and tumor cell survival during chronic hypoxia and further cytotoxic enhancement by the cyclooxygenase-2 inhibitor celecoxib. Journal of Biomedical Science. 14: 647-62. PMID 17440835 DOI: 10.1007/S11373-007-9173-3 |
0.524 |
|
2007 |
Charalambous C, Virrey J, Kardosh A, Jabbour MN, Qazi-Abdullah L, Pen L, Zidovetzki R, Schönthal AH, Chen TC, Hofman FM. Glioma-associated endothelial cells show evidence of replicative senescence. Experimental Cell Research. 313: 1192-202. PMID 17291495 DOI: 10.1016/J.Yexcr.2006.12.027 |
0.779 |
|
2006 |
Charalambous C, Chen TC, Hofman FM. Characteristics of tumor-associated endothelial cells derived from glioblastoma multiforme. Neurosurgical Focus. 20: E22. PMID 16709028 DOI: 10.3171/Foc.2006.20.4.E22 |
0.752 |
|
2006 |
Gupta V, Su YS, Wang W, Kardosh A, Liebes LF, Hofman FM, Schönthal AH, Chen TC. Enhancement of glioblastoma cell killing by combination treatment with temozolomide and tamoxifen or hypericin. Neurosurgical Focus. 20: E20. PMID 16709026 DOI: 10.3171/Foc.2006.20.4.13 |
0.305 |
|
2006 |
Pyrko P, Soriano N, Kardosh A, Liu YT, Uddin J, Petasis NA, Hofman FM, Chen CS, Chen TC, Schönthal AH. Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo Molecular Cancer. 5. PMID 16707021 DOI: 10.1186/1476-4598-5-19 |
0.528 |
|
2006 |
Milan J, Charalambous C, Elhag R, Chen TC, Li W, Guan S, Hofman FM, Zidovetzki R. Multiple signaling pathways are involved in endothelin-1-induced brain endothelial cell migration. American Journal of Physiology. Cell Physiology. 291: C155-64. PMID 16452160 DOI: 10.1152/Ajpcell.00239.2005 |
0.622 |
|
2005 |
Charalambous C, Pen LB, Su YS, Milan J, Chen TC, Hofman FM. Interleukin-8 differentially regulates migration of tumor-associated and normal human brain endothelial cells. Cancer Research. 65: 10347-54. PMID 16288024 DOI: 10.1158/0008-5472.Can-05-0949 |
0.606 |
|
2005 |
Kardosh A, Soriano N, Liu YT, Uddin J, Petasis NA, Hofman FM, Chen TC, Schönthal AH. Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib Blood. 106: 4330-4338. PMID 16123214 DOI: 10.1182/Blood-2005-07-2819 |
0.386 |
|
2005 |
Wu Z, Guo H, Chow N, Sallstrom J, Bell RD, Deane R, Brooks AI, Kanagala S, Rubio A, Sagare A, Liu D, Li F, Armstrong D, Gasiewicz T, Zidovetzki R, ... ... Hofman F, et al. Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease. Nature Medicine. 11: 959-65. PMID 16116430 DOI: 10.1038/Nm1287 |
0.375 |
|
2005 |
Charalambous C, Hofman FM, Chen TC. Functional and phenotypic differences between glioblastoma multiforme-derived and normal human brain endothelial cells. Journal of Neurosurgery. 102: 699-705. PMID 15871513 DOI: 10.3171/Jns.2005.102.4.0699 |
0.717 |
|
2005 |
Kardosh A, Wang W, Uddin J, Petasis NA, Hofman FM, Chen TC, Schönthal AH. Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo Cancer Biology and Therapy. 4: 571-582. PMID 15846081 DOI: 10.4161/Cbt.4.5.1699 |
0.38 |
|
2003 |
Wu Z, Hofman FM, Zlokovic BV. A simple method for isolation and characterization of mouse brain microvascular endothelial cells. Journal of Neuroscience Methods. 130: 53-63. PMID 14583404 DOI: 10.1016/S0165-0270(03)00206-1 |
0.439 |
|
2003 |
Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, ... ... Hofman F, et al. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nature Medicine. 9: 907-13. PMID 12808450 DOI: 10.1038/Nm890 |
0.354 |
|
2002 |
Chen TC, Wadsten P, Su S, Rawlinson N, Hofman FM, Hill CK, Schönthal AH. The type IV phosphodiesterase inhibitor rolipram induces expression of the cell cycle inhibitors p21(Cip1) and p27(Kip1), resulting in growth inhibition, increased differentiation, and subsequent apoptosis of malignant A-172 glioma cells. Cancer Biology & Therapy. 1: 268-76. PMID 12432276 DOI: 10.4161/Cbt.80 |
0.352 |
|
2002 |
Giri R, Selvaraj S, Miller CA, Hofman F, Yan SD, Stern D, Zlokovic BV, Kalra VK. Effect of endothelial cell polarity on beta-amyloid-induced migration of monocytes across normal and AD endothelium. American Journal of Physiology. Cell Physiology. 283: C895-904. PMID 12176746 DOI: 10.1152/Ajpcell.00293.2001 |
0.377 |
|
2001 |
Chen P, Shibata M, Zidovetzki R, Fisher M, Zlokovic BV, Hofman FM. Endothelin-1 and monocyte chemoattractant protein-1 modulation in ischemia and human brain-derived endothelial cell cultures Journal of Neuroimmunology. 116: 62-73. PMID 11311331 DOI: 10.1016/S0165-5728(01)00280-6 |
0.3 |
|
1999 |
Hofman FM. Vascular Endothelial Growth Factor Expression, Vascular Volume, and Capillary Permeability in Human Brain Tumors Neurosurgery. 44: 740-741. DOI: 10.1097/00006123-199904000-00024 |
0.457 |
|
1998 |
Zidovetzki R, Wang JL, Chen P, Jeyaseelan R, Hofman F. Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways. Aids Research and Human Retroviruses. 14: 825-33. PMID 9671211 DOI: 10.1089/Aid.1998.14.825 |
0.371 |
|
1997 |
Chen TC, Hinton DR, Sippy BD, Hofman FM. Soluble TNF-alpha receptors are constitutively shed and downregulate adhesion molecule expression in malignant gliomas. Journal of Neuropathology and Experimental Neurology. 56: 541-50. PMID 9143267 DOI: 10.1097/00005072-199705000-00010 |
0.32 |
|
1997 |
Chen TC, Hinton DR, Yong VW, Hofman FM. TGF-B2 and soluble p55 TNFR modulate VCAM-1 expression in glioma cells and brain derived endothelial cells. Journal of Neuroimmunology. 73: 155-61. PMID 9058771 DOI: 10.1016/S0165-5728(96)00190-7 |
0.419 |
|
1995 |
Sippy BD, Hofman FM, Wallach D, Hinton DR. Increased Expression of Tumor Necrosis Factor-α Receptors in the Brains of Patients With AIDS Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology. 10: 511-521. DOI: 10.1097/00042560-199510050-00004 |
0.33 |
|
1994 |
Hofman FM, Dohadwala MM, Wright AD, Hinton DR, Walker SM. Exogenous tat protein activates central nervous system-derived endothelial cells. Journal of Neuroimmunology. 54: 19-28. PMID 7523444 DOI: 10.1016/0165-5728(94)90226-7 |
0.346 |
|
1993 |
Mitchell MS, Harel W, Kan-Mitchell J, LeMay LG, Goedegebuure P, Huang XQ, Hofman F, Groshen S. Active specific immunotherapy of melanoma with allogeneic cell lysates. Rationale, results, and possible mechanisms of action Annals of the New York Academy of Sciences. 690: 153-166. PMID 8368734 DOI: 10.1111/J.1749-6632.1993.Tb44005.X |
0.354 |
|
1993 |
Hofman F, Wright A, Dohadwala M, Wong-Staal F, Walker S. Exogenous tat protein activates human endothelial cells [see comments] Blood. 82: 2774-2780. DOI: 10.1182/Blood.V82.9.2774.2774 |
0.443 |
|
1992 |
Schneider J, Hofman FM, Apuzzo ML, Hinton DR. Cytokines and immunoregulatory molecules in malignant glial neoplasms. Journal of Neurosurgery. 77: 265-73. PMID 1625016 DOI: 10.3171/Jns.1992.77.2.0265 |
0.351 |
|
1991 |
Hofman FM, Hinton DR, Baemayr J, Weil M, Merrill JE. Lymphokines and immunoregulatory molecules in subacute sclerosing panencephalitis. Clinical Immunology and Immunopathology. 58: 331-42. PMID 1900461 DOI: 10.1016/0090-1229(91)90124-S |
0.309 |
|
1991 |
Sullivan L, Sano S, Pirmez C, Salgame P, Mueller C, Hofman F, Uyemura K, Rea TH, Bloom BR, Modlin RL. Expression of adhesion molecules in leprosy lesions. Infection and Immunity. 59: 4154-60. PMID 1718871 DOI: 10.1128/Iai.59.11.4154-4160.1991 |
0.335 |
|
1989 |
Bui HT, Linthicum FH, Hofman FM, Bowman CA, House WF. An immunohistochemical study of the endolymphatic sac in patients with acoustic tumors. The Laryngoscope. 99: 775-8. PMID 2755283 DOI: 10.1288/00005537-198908000-00001 |
0.374 |
|
1988 |
Kanowith-Klein S, Hofman F, Saxon A. Expression of Fc epsilon receptors and surface and cytoplasmic IgE on human fetal and adult lymphopoietic tissue. Clinical Immunology and Immunopathology. 48: 214-24. PMID 2968873 DOI: 10.1016/0090-1229(88)90085-2 |
0.344 |
|
1984 |
von Hanwehr RI, Hofman FM, Taylor CR, Apuzzo ML. Mononuclear lymphoid populations infiltrating the microenvironment of primary CNS tumors. Characterization of cell subsets with monoclonal antibodies. Journal of Neurosurgery. 60: 1138-47. PMID 6374063 DOI: 10.3171/jns.1984.60.6.1138 |
0.525 |
|
1984 |
Yanagihara ET, Parker JW, Meyer PR, Cain MJ, Hofman F, Lukes RJ. Mycosis fungoides/Sezary's syndrome progressing to immunoblastic sarcoma. A T-cell lymphoproliferation with both helper and suppressor phenotypes. American Journal of Clinical Pathology. 81: 249-57. PMID 6230003 DOI: 10.1093/Ajcp/81.2.249 |
0.376 |
|
1984 |
Jephthah J, Terasaki P, Hofman F, Wolde-Marian W, Peter J, Billing R. A cytotoxic monoclonal antibody detecting a novel B cell membrane antigen expressed predominantly on cells bearing surface membrane immunoglobulin Blood. 63: 319-325. DOI: 10.1182/Blood.V63.2.319.Bloodjournal632319 |
0.367 |
|
1983 |
Hofman F, Yanagihara E, Byrne B, Billing R, Baird S, Frisman D, Taylor C. Analysis of B-cell antigens in normal reactive lymphoid tissue using four B-cell monoclonal antibodies Blood. 62: 775-783. DOI: 10.1182/Blood.V62.4.775.Bloodjournal624775 |
0.322 |
|
1983 |
Deng C, Terasaki P, Iwaki Y, Hofman F, Koeffler P, Cahan L, El Awar N, Billing R. A monoclonal antibody cross-reactive with human platelets, megakaryocytes, and common acute lymphocytic leukemia cells Blood. 61: 759-764. DOI: 10.1182/Blood.V61.4.759.Bloodjournal614759 |
0.323 |
|
1981 |
Hofman F, Rand N, Fahey JL. Adherent cell requirement for PWM-stimulated factor suppression of natural killer cytotoxicity. Cellular Immunology. 58: 356-365. PMID 6452221 DOI: 10.1016/0008-8749(81)90229-X |
0.383 |
|
1980 |
Hofman F, Spina CA, Rand N, Fahey JL. Soluble suppressor factor produced by pokeweed mitogen-stimulated human peripheral blood leukocytes☆ Cellular Immunology. 55: 20-31. PMID 6448693 DOI: 10.1016/0008-8749(80)90133-1 |
0.417 |
|
1976 |
Hofman F, Globerson A. Immunological potential of yolk sac cells. Advances in Experimental Medicine and Biology. 66: 51-7. PMID 131474 DOI: 10.1007/978-1-4613-4355-4_7 |
0.364 |
|
1974 |
Scollay RG, Hofman F, Globerson A. Graft-versus-host reaction in F 1 recipients in the absence of donor (parental) cell proliferation. European Journal of Immunology. 4: 490-3. PMID 4153366 DOI: 10.1002/Eji.1830040709 |
0.331 |
|
1973 |
Hofman F, Globerson A. Graft-versus-host response inducedin vitro by mouse yolk sac cells European Journal of Immunology. 3: 179-181. DOI: 10.1002/Eji.1830030314 |
0.341 |
|
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