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Christopher R. Gault, Ph.D. - Publications

Affiliations: 
2012 Medical University of South Carolina, Charleston, SC, United States 
Area:
Molecular Biology, Cell Biology, Oncology
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Trayssac M, Clarke CJ, Stith JL, Snider JM, Newen N, Gault CR, Hannun YA, Obeid LM. Targeting sphingosine kinase 1 (SK1) enhances oncogene-induced senescence through ceramide synthase 2 (CerS2)-mediated generation of very-long-chain ceramides. Cell Death & Disease. 12: 27. PMID 33414460 DOI: 10.1038/s41419-020-03281-4  0.532
2012 Gault CR, Eblen ST, Neumann CA, Hannun YA, Obeid LM. Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner. The Journal of Biological Chemistry. 287: 31794-803. PMID 22833671 DOI: 10.1074/Jbc.M112.385765  0.583
2011 Gault CR, Obeid LM. Still benched on its way to the bedside: sphingosine kinase 1 as an emerging target in cancer chemotherapy. Critical Reviews in Biochemistry and Molecular Biology. 46: 342-51. PMID 21787121 DOI: 10.3109/10409238.2011.597737  0.563
2011 Salas A, Ponnusamy S, Senkal CE, Meyers-Needham M, Selvam SP, Saddoughi SA, Apohan E, Sentelle RD, Smith C, Gault CR, Obeid LM, El-Shewy HM, Oaks J, Santhanam R, Marcucci G, et al. Sphingosine kinase-1 and sphingosine 1-phosphate receptor 2 mediate Bcr-Abl1 stability and drug resistance by modulation of protein phosphatase 2A. Blood. 117: 5941-52. PMID 21527515 DOI: 10.1182/Blood-2010-08-300772  0.596
2011 Jenkins RW, Clarke CJ, Canals D, Snider AJ, Gault CR, Heffernan-Stroud L, Wu BX, Simbari F, Roddy P, Kitatani K, Obeid LM, Hannun YA. Regulation of CC ligand 5/RANTES by acid sphingomyelinase and acid ceramidase. The Journal of Biological Chemistry. 286: 13292-303. PMID 21335555 DOI: 10.1074/Jbc.M110.163378  0.431
2010 Gault CR, Obeid LM, Hannun YA. An overview of sphingolipid metabolism: from synthesis to breakdown. Advances in Experimental Medicine and Biology. 688: 1-23. PMID 20919643 DOI: 10.1007/978-1-4419-6741-1_1  0.567
2010 Anelli V, Gault CR, Snider AJ, Obeid LM. Role of sphingosine kinase-1 in paracrine/transcellular angiogenesis and lymphangiogenesis in vitro. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2727-38. PMID 20335228 DOI: 10.1096/Fj.09-150540  0.598
2009 Mahdy AE, Cheng JC, Li J, Elojeimy S, Meacham WD, Turner LS, Bai A, Gault CR, McPherson AS, Garcia N, Beckham TH, Saad A, Bielawska A, Bielawski J, Hannun YA, et al. Acid ceramidase upregulation in prostate cancer cells confers resistance to radiation: AC inhibition, a potential radiosensitizer. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 430-8. PMID 19107118 DOI: 10.1038/Mt.2008.281  0.308
2008 Anelli V, Gault CR, Cheng AB, Obeid LM. Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2. The Journal of Biological Chemistry. 283: 3365-75. PMID 18055454 DOI: 10.1074/Jbc.M708241200  0.568
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