Year |
Citation |
Score |
2017 |
Dalwadi DA, Schetz JA. Comparative exploration of the structure-activity space of cloned α-like octopamine receptors from a marine and a terrestrial arthropod. Molecular Pharmacology. PMID 28663279 DOI: 10.1124/Mol.117.108456 |
0.37 |
|
2017 |
Huang R, Chen Z, Dolan S, Schetz JA, Dillon GH. The dual modulatory effects of efavirenz on GABAA receptors are mediated via two distinct sites. Neuropharmacology. PMID 28456686 DOI: 10.1016/J.Neuropharm.2017.04.038 |
0.356 |
|
2016 |
Dalwadi DA, Kim S, Amdani SM, Chen Z, Huang RQ, Schetz JA. Molecular mechanisms of serotonergic action of the HIV-1 antiretroviral efavirenz. Pharmacological Research. PMID 27157251 DOI: 10.1016/J.Phrs.2016.04.028 |
0.372 |
|
2014 |
Leopoldo M, Selivanova SV, Müller A, Lacivita E, Schetz JA, Ametamey SM. In vitro and in vivo evaluation of N-{2-[4-(3-Cyanopyridin-2-yl)piperazin-1-yl]ethyl}-3-[(11) C]methoxybenz-amide, a positron emission tomography (PET) radioligand for dopamine D4 receptors, in rodents. Chemistry & Biodiversity. 11: 1298-308. PMID 25238073 DOI: 10.1002/Cbdv.201400178 |
0.391 |
|
2014 |
Saunders C, Siuta M, Robertson SD, Davis AR, Sauer J, Matthies HJ, Gresch PJ, Airey DC, Lindsley CW, Schetz JA, Niswender KD, Veenstra-Vanderweele JM, Galli A. Neuronal ablation of p-Akt at Ser473 leads to altered 5-HT1A/2A receptor function. Neurochemistry International. 73: 113-21. PMID 24090638 DOI: 10.1016/J.Neuint.2013.09.015 |
0.334 |
|
2013 |
Gatch MB, Kozlenkov A, Huang RQ, Yang W, Nguyen JD, González-Maeso J, Rice KC, France CP, Dillon GH, Forster MJ, Schetz JA. The HIV antiretroviral drug efavirenz has LSD-like properties. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 2373-84. PMID 23702798 DOI: 10.1038/Npp.2013.135 |
0.332 |
|
2012 |
Ericksen SS, Cummings DF, Teer ME, Amdani S, Schetz JA. Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor. The Journal of Pharmacology and Experimental Therapeutics. 342: 472-85. PMID 22588261 DOI: 10.1124/Jpet.112.193979 |
0.388 |
|
2011 |
Voulalas PJ, Schetz J, Undieh AS. Differential subcellular distribution of rat brain dopamine receptors and subtype-specific redistribution induced by cocaine. Molecular and Cellular Neurosciences. 46: 645-54. PMID 21236347 DOI: 10.1016/J.Mcn.2011.01.004 |
0.372 |
|
2010 |
Lacivita E, De Giorgio P, Lee IT, Rodeheaver SI, Weiss BA, Fracasso C, Caccia S, Berardi F, Perrone R, Zhang MR, Maeda J, Higuchi M, Suhara T, Schetz JA, Leopoldo M. Design, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptors. Journal of Medicinal Chemistry. 53: 7344-55. PMID 20873719 DOI: 10.1021/Jm100925M |
0.435 |
|
2010 |
Cummings DF, Canseco DC, Sheth P, Johnson JE, Schetz JA. Synthesis and structure-affinity relationships of novel small molecule natural product derivatives capable of discriminating between serotonin 5-HT1A, 5-HT2A, 5-HT2C receptor subtypes. Bioorganic & Medicinal Chemistry. 18: 4783-92. PMID 20570529 DOI: 10.1016/J.Bmc.2010.05.017 |
0.425 |
|
2010 |
Cummings DF, Ericksen SS, Goetz A, Schetz JA. Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548. The Journal of Pharmacology and Experimental Therapeutics. 333: 682-95. PMID 20215412 DOI: 10.1124/Jpet.109.164962 |
0.396 |
|
2009 |
Cummings DF, Ericksen SS, Schetz JA. Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity. Journal of Neurochemistry. 110: 45-57. PMID 19486266 DOI: 10.1111/J.1471-4159.2009.06103.X |
0.41 |
|
2009 |
Angarano MB, McMahon RF, Schetz JA. Cannabinoids inhibit zebra mussel (Dreissena polymorpha) byssal attachment: a potentially green antifouling technology. Biofouling. 25: 127-38. PMID 19037826 DOI: 10.1080/08927010802592743 |
0.614 |
|
2009 |
Ericksen SS, Cummings DF, Weinstein H, Schetz JA. Ligand selectivity of D2 dopamine receptors is modulated by changes in local dynamics produced by sodium binding. The Journal of Pharmacology and Experimental Therapeutics. 328: 40-54. PMID 18849360 DOI: 10.1124/Jpet.108.141531 |
0.39 |
|
2009 |
Chang CW, Poteet E, Schetz JA, Gümüş ZH, Weinstein H. Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation. Neuropharmacology. 56: 213-25. PMID 18762202 DOI: 10.1016/J.Neuropharm.2008.07.049 |
0.351 |
|
2008 |
Lee IT, Chen S, Schetz JA. An unambiguous assay for the cloned human sigma1 receptor reveals high affinity interactions with dopamine D4 receptor selective compounds and a distinct structure-affinity relationship for butyrophenones. European Journal of Pharmacology. 578: 123-36. PMID 17961544 DOI: 10.1016/J.Ejphar.2007.09.020 |
0.45 |
|
2007 |
Schetz JA, Perez E, Liu R, Chen S, Lee I, Simpkins JW. A prototypical Sigma-1 receptor antagonist protects against brain ischemia. Brain Research. 1181: 1-9. PMID 17919467 DOI: 10.1016/J.Brainres.2007.08.068 |
0.358 |
|
2007 |
Angarano MB, McMahon RF, Hawkins DL, Schetz JA. Exploration of structure-antifouling relationships of capsaicin-like compounds that inhibit zebra mussel (Dreissena polymorpha) macrofouling. Biofouling. 23: 295-305. PMID 17852065 DOI: 10.1080/08927010701371439 |
0.618 |
|
2005 |
Schetz JA. Allosteric modulation of dopamine receptors. Mini Reviews in Medicinal Chemistry. 5: 555-61. PMID 15974933 DOI: 10.2174/1389557054023260 |
0.361 |
|
2005 |
Floresca CZ, Chen S, Kortagere S, Schetz JA. Reciprocal mutations in TM2/TM3 in a D2 dopamine receptor background confirms the importance of this microdomain as a selective determinant of para-halogenated 1,4-disubstituted aromatic piperazines. Archiv Der Pharmazie. 338: 268-75. PMID 15952239 DOI: 10.1002/Ardp.200400993 |
0.381 |
|
2004 |
Floresca CZ, Schetz JA. Dopamine receptor microdomains involved in molecular recognition and the regulation of drug affinity and function. Journal of Receptor and Signal Transduction Research. 24: 207-39. PMID 15521362 DOI: 10.1081/Rrs-200032088 |
0.364 |
|
2004 |
Kortagere S, Gmeiner P, Weinstein H, Schetz JA. Certain 1,4-disubstituted aromatic piperidines and piperazines with extreme selectivity for the dopamine D4 receptor interact with a common receptor microdomain. Molecular Pharmacology. 66: 1491-9. PMID 15448188 DOI: 10.1124/Mol.104.001321 |
0.374 |
|
2004 |
Boeckler F, Russig H, Zhang W, Löber S, Schetz J, Hübner H, Ferger B, Gmeiner P, Feldon J. FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. Psychopharmacology. 175: 7-17. PMID 15007532 DOI: 10.1007/S00213-004-1782-1 |
0.41 |
|
2003 |
Schetz JA, Kim OJ, Sibley DR. Pharmacological characterization of mammalian D1 and D2 dopamine receptors expressed in Drosophila Schneider-2 cells. Journal of Receptor and Signal Transduction Research. 23: 99-109. PMID 12680592 DOI: 10.1081/RRS-120018763 |
0.301 |
|
2000 |
Schetz JA, Sibley DR. Tandem sulfur-containing amino acids are epicritical determinants of dopamine D(2) receptor pharmacology. European Journal of Pharmacology. 388: R5-7. PMID 10666514 DOI: 10.1016/S0014-2999(99)00867-5 |
0.338 |
|
1999 |
Lawler CP, Prioleau C, Lewis MM, Mak C, Jiang D, Schetz JA, Gonzalez AM, Sibley DR, Mailman RB. Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 612-27. PMID 10327430 DOI: 10.1016/S0893-133X(98)00099-2 |
0.443 |
|
1999 |
Schetz JA, Chu A, Sibley DR. Zinc modulates antagonist interactions with D2-like dopamine receptors through distinct molecular mechanisms. The Journal of Pharmacology and Experimental Therapeutics. 289: 956-64. PMID 10215675 |
0.32 |
|
1999 |
Wolfe SE, Howard DE, Schetz JA, Cheng CJ, Webber R, Beatty DM, Chronwall BM, Morris SJ. Dopamine D2-receptor isoforms expressed in AtT20 cells inhibit Q-type high-voltage-activated Ca2+ channels via a membrane-delimited pathway. Journal of Neurochemistry. 72: 479-90. PMID 9930719 DOI: 10.1046/J.1471-4159.1999.0720479.X |
0.323 |
|
1998 |
Woodhouse EC, Amanatullah DF, Schetz JA, Liotta LA, Stracke ML, Clair T. Adenosine receptor mediates motility in human melanoma cells. Biochemical and Biophysical Research Communications. 246: 888-94. PMID 9618307 DOI: 10.1006/Bbrc.1998.8714 |
0.343 |
|
1997 |
Schetz JA, Sibley DR. Zinc allosterically modulates antagonist binding to cloned D1 and D2 dopamine receptors. Journal of Neurochemistry. 68: 1990-7. PMID 9109525 DOI: 10.1046/J.1471-4159.1997.68051990.X |
0.408 |
|
Show low-probability matches. |