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Kshitij Wagh, Ph.D. - Publications

Affiliations: 
2013 Graduate School - New Brunswick Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
General Biophysics, Genetics, Bioinformatics Biology
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Misra M, Jeffy J, Liao C, Pickthorn S, Wagh K, Herschhorn A. HIResist: a database of HIV-1 resistance to broadly neutralizing antibodies. Bioinformatics (Oxford, England). 40. PMID 38426331 DOI: 10.1093/bioinformatics/btae103  0.356
2023 Henderson R, Anasti K, Manne K, Stalls V, Saunders C, Bililign Y, Williams A, Bubphamala P, Montani M, Kachhap S, Li J, Jaing C, Newman A, Cain D, Lu X, ... ... Wagh K, et al. Engineering immunogens that select for specific mutations in HIV broadly neutralizing antibodies. Biorxiv : the Preprint Server For Biology. PMID 38168268 DOI: 10.1101/2023.12.15.571700  0.341
2023 Lasrado N, Collier AY, Hachmann NP, Miller J, Rowe M, Schonberg ED, Rodrigues SL, LaPiana A, Patio RC, Anand T, Fisher J, Mazurek CR, Guan R, Wagh K, Theiler J, et al. Neutralization escape by SARS-CoV-2 Omicron subvariant BA.2.86. Vaccine. PMID 37872011 DOI: 10.1016/j.vaccine.2023.10.051  0.312
2023 Wagh K, Seaman MS. Divide and conquer: broadly neutralizing antibody combinations for improved HIV-1 viral coverage. Current Opinion in Hiv and Aids. 18: 164-170. PMID 37249911 DOI: 10.1097/COH.0000000000000800  0.352
2023 Henderson R, Zhou Y, Stalls V, Wiehe K, Saunders KO, Wagh K, Anasti K, Barr M, Parks R, Alam SM, Korber B, Haynes BF, Bartesaghi A, Acharya P. Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage. Nature Communications. 14: 2782. PMID 37188681 DOI: 10.1038/s41467-023-38108-1  0.388
2023 Haynes BF, Wiehe K, Borrow P, Saunders KO, Korber B, Wagh K, McMichael AJ, Kelsoe G, Hahn BH, Alt F, Shaw GM. Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies. Nature Reviews. Immunology. PMID 36859597 DOI: 10.1038/s41577-023-00854-0  0.351
2023 Bibollet-Ruche F, Russell RM, Ding W, Liu W, Li Y, Wagh K, Wrapp D, Habib R, Skelly AN, Roark RS, Sherrill-Mix S, Wang S, Rando J, Lindemuth E, Cruickshank K, et al. A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies. Mbio. e0337022. PMID 36629414 DOI: 10.1128/mbio.03370-22  0.363
2022 Haynes BF, Wiehe K, Borrrow P, Saunders KO, Korber B, Wagh K, McMichael AJ, Kelsoe G, Hahn BH, Alt F, Shaw GM. Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies. Nature Reviews. Immunology. PMID 35962033 DOI: 10.1038/s41577-022-00753-w  0.364
2022 Julg B, Stephenson KE, Wagh K, Tan SC, Zash R, Walsh S, Ansel J, Kanjilal D, Nkolola J, Walker-Sperling VEK, Ophel J, Yanosick K, Borducchi EN, Maxfield L, Abbink P, et al. Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial. Nature Medicine. PMID 35551291 DOI: 10.1038/s41591-022-01815-1  0.318
2022 Mu Z, Wiehe K, Saunders KO, Henderson R, Cain DW, Parks R, Martik D, Mansouri K, Edwards RJ, Newman A, Lu X, Xia SM, Eaton A, Bonsignori M, Montefiori D, ... ... Wagh K, et al. mRNA-encoded HIV-1 Env trimer ferritin nanoparticles induce monoclonal antibodies that neutralize heterologous HIV-1 isolates in mice. Cell Reports. 38: 110514. PMID 35294883 DOI: 10.1016/j.celrep.2022.110514  0.318
2021 Wagh K, van Gils MJ, Gristick H, Schommers P. Editorial: Novel Concepts in Using Broadly Neutralizing Antibodies for HIV-1 Treatment and Prevention. Frontiers in Immunology. 12: 823576. PMID 34992615 DOI: 10.3389/fimmu.2021.823576  0.316
2021 Stephenson KE, Julg B, Tan CS, Zash R, Walsh SR, Rolle CP, Monczor AN, Lupo S, Gelderblom HC, Ansel JL, Kanjilal DG, Maxfield LF, Nkolola J, Borducchi EN, Abbink P, ... ... Wagh K, et al. Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial. Nature Medicine. PMID 34621054 DOI: 10.1038/s41591-021-01509-0  0.355
2021 Cai F, Chen WH, Wu W, Jones JA, Choe M, Gohain N, Shen X, LaBranche C, Eaton A, Sutherland L, Lee EM, Hernandez GE, Wu NR, Scearce R, Seaman MS, ... ... Wagh K, et al. Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates. Plos Pathogens. 17: e1009624. PMID 34086838 DOI: 10.1371/journal.ppat.1009624  0.402
2021 Shen X, Tang H, McDanal C, Wagh K, Fischer W, Theiler J, Yoon H, Li D, Haynes BF, Sanders KO, Gnanakaran S, Hengartner N, Pajon R, Smith G, Dubovsky F, et al. SARS-CoV-2 variant B.1.1.7 is susceptible to neutralizing antibodies elicited by ancestral Spike vaccines. Biorxiv : the Preprint Server For Biology. PMID 33532764 DOI: 10.1101/2021.01.27.428516  0.314
2020 Roark RS, Li H, Williams WB, Chug H, Mason RD, Gorman J, Wang S, Lee FH, Rando J, Bonsignori M, Hwang KK, Saunders KO, Wiehe K, Moody MA, Hraber PT, ... Wagh K, et al. Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science (New York, N.Y.). PMID 33214287 DOI: 10.1126/science.abd2638  0.385
2020 Wagh K, Hahn BH, Korber B. Hitting the sweet spot: exploiting HIV-1 glycan shield for induction of broadly neutralizing antibodies. Current Opinion in Hiv and Aids. PMID 32675574 DOI: 10.1097/Coh.0000000000000639  0.448
2020 Stephenson KE, Wagh K, Korber B, Barouch DH. Vaccines and Broadly Neutralizing Antibodies for HIV-1 Prevention. Annual Review of Immunology. 38: 673-703. PMID 32340576 DOI: 10.1146/Annurev-Immunol-080219-023629  0.45
2019 Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, et al. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host & Microbe. 26: 296. PMID 31415756 DOI: 10.1016/j.chom.2019.07.016  0.345
2019 Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, et al. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host & Microbe. 25: 59-72.e8. PMID 30629920 DOI: 10.1016/J.Chom.2018.12.001  0.465
2018 Wagh K, Kreider EF, Li Y, Barbian HJ, Learn GH, Giorgi E, Hraber PT, Decker TG, Smith AG, Gondim MV, Gillis L, Wandzilak J, Chuang GY, Rawi R, Cai F, et al. Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth. Cell Reports. 25: 893-908.e7. PMID 30355496 DOI: 10.1016/J.Celrep.2018.09.087  0.486
2018 Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, et al. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 174: 938-952.e13. PMID 30096313 DOI: 10.1016/J.Cell.2018.07.033  0.302
2018 Wagh K, Seaman MS, Zingg M, Fitzsimons T, Barouch DH, Burton DR, Connors M, Ho DD, Mascola JR, Nussenzweig MC, Ravetch J, Gautam R, Martin MA, Montefiori DC, Korber B. Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections. Plos Pathogens. 14: e1006860. PMID 29505593 DOI: 10.1371/Journal.Ppat.1006860  0.426
2018 Kwon YD, Chuang GY, Zhang B, Bailer RT, Doria-Rose NA, Gindin TS, Lin B, Louder MK, McKee K, O'Dell S, Pegu A, Schmidt SD, Asokan M, Chen X, Choe M, ... ... Wagh K, et al. Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody. Cell Reports. 22: 1798-1809. PMID 29444432 DOI: 10.1016/J.Celrep.2018.01.023  0.407
2018 Hraber P, Korber B, Wagh K, Montefiori D, Roederer M. A single, continuous metric to define tiered serum neutralization potency against HIV. Elife. 7. PMID 29350181 DOI: 10.7554/Elife.31805  0.467
2017 Julg B, Liu PT, Wagh K, Fischer WM, Abbink P, Mercado NB, Whitney JB, Nkolola JP, McMahan K, Tartaglia LJ, Borducchi EN, Khatiwada S, Kamath M, LeSuer JA, Seaman MS, et al. Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail. Science Translational Medicine. 9. PMID 28931655 DOI: 10.1126/Scitranslmed.Aao4235  0.498
2017 Julg B, Tartaglia LJ, Keele BF, Wagh K, Pegu A, Sok D, Abbink P, Schmidt SD, Wang K, Chen X, Gordon Joyce M, Georgiev IS, Choe M, Kwong PD, Doria-Rose NA, et al. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Science Translational Medicine. 9. PMID 28878010 DOI: 10.1126/Scitranslmed.Aal1321  0.461
2017 Williams LD, Ofek G, Schätzle S, McDaniel JR, Lu X, Nicely NI, Wu L, Lougheed CS, Bradley T, Louder MK, McKee K, Bailer RT, O'Dell S, Georgiev IS, Seaman MS, ... ... Wagh K, et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Science Immunology. 2. PMID 28783671 DOI: 10.1126/Sciimmunol.Aal2200  0.402
2017 Cai Y, Karaca-Griffin S, Chen J, Tian S, Fredette N, Linton CE, Rits-Volloch S, Lu J, Wagh K, Theiler J, Korber B, Seaman MS, Harrison SC, Carfi A, Chen B. Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396421 DOI: 10.1073/Pnas.1700634114  0.398
2017 Bonsignori M, Kreider EF, Fera D, Meyerhoff RR, Bradley T, Wiehe K, Alam SM, Aussedat B, Walkowicz WE, Hwang KK, Saunders KO, Zhang R, Gladden MA, Monroe A, Kumar A, ... ... Wagh K, et al. Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Science Translational Medicine. 9. PMID 28298420 DOI: 10.1126/Scitranslmed.Aai7514  0.469
2017 Korber B, Hraber P, Wagh K, Hahn BH. Polyvalent vaccine approaches to combat HIV-1 diversity. Immunological Reviews. 275: 230-244. PMID 28133800 DOI: 10.1111/Imr.12516  0.454
2016 Zoubchenok D, Veillette M, Prévost J, Sanders-Buell E, Wagh K, Korber B, Chenine AL, Finzi A. Histidine 375 Modulates CD4 Binding in HIV-1 CRF01_AE Envelope Glycoproteins. Journal of Virology. PMID 27928014 DOI: 10.1128/Jvi.02151-16  0.328
2016 Rademeyer C, Korber B, Seaman MS, Giorgi EE, Thebus R, Robles A, Sheward DJ, Wagh K, Garrity J, Carey BR, Gao H, Greene KM, Tang H, Bandawe GP, Marais JC, et al. Features of Recently Transmitted HIV-1 Clade C Viruses that Impact Antibody Recognition: Implications for Active and Passive Immunization. Plos Pathogens. 12: e1005742. PMID 27434311 DOI: 10.1371/Journal.Ppat.1005742  0.497
2016 Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, et al. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. Cell. PMID 27114034 DOI: 10.1016/J.Cell.2016.04.010  0.415
2016 Wagh K, Bhattacharya T, Williamson C, Robles A, Bayne M, Garrity J, Rist M, Rademeyer C, Yoon H, Lapedes A, Gao H, Greene K, Louder MK, Kong R, Karim SA, et al. Optimal Combinations of Broadly Neutralizing Antibodies for Prevention and Treatment of HIV-1 Clade C Infection. Plos Pathogens. 12: e1005520. PMID 27028935 DOI: 10.1371/Journal.Ppat.1005520  0.459
2015 Hraber P, Korber B, Wagh K, Giorgi EE, Bhattacharya T, Gnanakaran S, Lapedes AS, Learn GH, Kreider EF, Li Y, Shaw GM, Hahn BH, Montefiori DC, Alam SM, Bonsignori M, et al. Longitudinal Antigenic Sequences and Sites from Intra-Host Evolution (LASSIE) Identifies Immune-Selected HIV Variants. Viruses. 7: 5443-75. PMID 26506369 DOI: 10.3390/V7102881  0.355
2015 Kong R, Louder MK, Wagh K, Bailer RT, deCamp A, Greene K, Gao H, Taft JD, Gazumyan A, Liu C, Nussenzweig MC, Korber B, Montefiori DC, Mascola JR. Improving neutralization potency and breadth by combining broadly reactive HIV-1 antibodies targeting major neutralization epitopes. Journal of Virology. 89: 2659-71. PMID 25520506 DOI: 10.1128/Jvi.03136-14  0.464
2015 Abbink P, Maxfield LF, Ng'ang'a D, Borducchi EN, Iampietro MJ, Bricault CA, Teigler JE, Blackmore S, Parenteau L, Wagh K, Handley SA, Zhao G, Virgin HW, Korber B, Barouch DH. Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors. Journal of Virology. 89: 1512-22. PMID 25410856 DOI: 10.1128/Jvi.02950-14  0.369
2014 Wagh K, Bhatia A, Greenbaum BD, Bhanot G. Bird to human transmission biases and vaccine escape mutants in H5N1 infections. Plos One. 9: e100754. PMID 24988306 DOI: 10.1371/Journal.Pone.0100754  0.554
2012 Wagh K, Bhatia A, Alexe G, Reddy A, Ravikumar V, Seiler M, Boemo M, Yao M, Cronk L, Naqvi A, Ganesan S, Levine AJ, Bhanot G. Lactase persistence and lipid pathway selection in the Maasai. Plos One. 7: e44751. PMID 23028602 DOI: 10.1371/Journal.Pone.0044751  0.529
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