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Colin F. Greineder, Ph.D. - Publications

Affiliations: 
2014 Pharmacology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Pharmacology, Biomedical Engineering
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44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pornnoppadol G, Bond LG, Lucas MJ, Zupancic JM, Kuo YH, Zhang B, Greineder CF, Tessier PM. Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs. Cell Chemical Biology. PMID 37890480 DOI: 10.1016/j.chembiol.2023.09.008  0.357
2023 Nong J, Glassman PM, Myerson JW, Zuluaga-Ramirez V, Rodriguez-Garcia A, Mukalel A, Omo-Lamai S, Walsh LR, Zamora ME, Gong X, Wang Z, Bhamidipati K, Kiseleva RY, Villa CH, Greineder CF, et al. Targeted Nanocarriers Co-Opting Pulmonary Intravascular Leukocytes for Drug Delivery to the Injured Brain. Acs Nano. PMID 37432926 DOI: 10.1021/acsnano.2c08275  0.549
2023 Pornnoppadol G, Bond LG, Lucas MJ, Zupancic JM, Kuo YH, Zhang B, Greineder CF, Tessier PM. Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs. Biorxiv : the Preprint Server For Biology. PMID 37162883 DOI: 10.1101/2023.04.29.538811  0.335
2022 Glassman PM, Villa CH, Marcos-Contreras OA, Hood ED, Walsh LR, Greineder CF, Myerson JW, Shuvaeva T, Puentes L, Brenner JS, Siegel DL, Muzykantov VR. Targeted In Vivo Loading of Red Blood Cells Markedly Prolongs Nanocarrier Circulation. Bioconjugate Chemistry. PMID 35710322 DOI: 10.1021/acs.bioconjchem.2c00196  0.588
2021 Myerson JW, Patel PN, Rubey KM, Zamora ME, Zaleski MH, Habibi N, Walsh LR, Lee YW, Luther DC, Ferguson LT, Marcos-Contreras OA, Glassman PM, Mazaleuskaya LL, Johnston I, Hood ED, ... ... Greineder CF, et al. Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation. Nature Nanotechnology. PMID 34795440 DOI: 10.1038/s41565-021-00997-y  0.478
2020 Kiseleva RY, Glassman PG, LeForte KM, Walsh LR, Villa CH, Shuvaev VV, Myerson JW, Aprelev PA, Marcos-Contreras OA, Muzykantov VR, Greineder CF. Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32738178 DOI: 10.1096/Fj.201902515Rr  0.598
2020 Glassman PM, Walsh LR, Villa CH, Marcos-Contreras OA, Hood ED, Muzykantov VR, Greineder CF. Molecularly Engineered Nanobodies for Tunable Pharmacokinetics and Drug Delivery. Bioconjugate Chemistry. PMID 32167754 DOI: 10.1021/Acs.Bioconjchem.0C00003  0.685
2020 Marcos-Contreras OA, Greineder CF, Kiseleva RY, Parhiz H, Walsh LR, Zuluaga-Ramirez V, Myerson JW, Hood ED, Villa CH, Tombacz I, Pardi N, Seliga A, Mui BL, Tam YK, Glassman PM, et al. Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier. Proceedings of the National Academy of Sciences of the United States of America. PMID 32005712 DOI: 10.1073/Pnas.1912012117  0.612
2019 Marcos-Contreras OA, Brenner JS, Kiseleva RY, Zuluaga-Ramirez V, Greineder CF, Villa CH, Hood ED, Myerson JW, Muro S, Persidsky Y, Muzykantov VR. Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30871995 DOI: 10.1016/J.Jconrel.2019.03.008  0.628
2018 Hood ED, Greineder CF, Shuvaeva T, Walsh L, Villa CH, Muzykantov VR. Vascular targeting of radiolabeled liposomes with bio-orthogonally conjugated ligands: single chain fragments provide higher specificity than antibodies. Bioconjugate Chemistry. PMID 30240185 DOI: 10.1021/Acs.Bioconjchem.8B00564  0.681
2018 Myerson JW, Braender B, Mcpherson O, Glassman PM, Kiseleva RY, Shuvaev VV, Marcos-Contreras O, Grady ME, Lee HS, Greineder CF, Stan RV, Composto RJ, Eckmann DM, Muzykantov VR. Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles. Advanced Materials (Deerfield Beach, Fla.). e1802373. PMID 29956381 DOI: 10.1002/Adma.201802373  0.612
2018 Khoshnejad M, Greineder CF, Pulsipher KW, Villa CH, Altun B, Pan DC, Tsourkas A, Dmochowski IJ, Muzykantov V. Ferritin nanocages with biologically orthogonal conjugation for vascular targeting and imaging. Bioconjugate Chemistry. PMID 29429330 DOI: 10.1021/Acs.Bioconjchem.8B00004  0.651
2018 Khoshnejad M, Brenner JS, Motley W, Parhiz H, Greineder CF, Villa CH, Marcos-Contreras OA, Tsourkas A, Muzykantov VR. Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9. Scientific Reports. 8: 1760. PMID 29379029 DOI: 10.1038/S41598-018-19784-2  0.589
2018 Kiseleva RY, Greineder CF, Villa CH, Marcos-Contreras OA, Hood ED, Shuvaev VV, DeLisser HM, Muzykantov VR. Vascular endothelial effects of collaborative binding to platelet/endothelial cell adhesion molecule-1 (PECAM-1). Scientific Reports. 8: 1510. PMID 29367646 DOI: 10.1038/S41598-018-20027-7  0.713
2018 Villa CH, Pan DC, Johnston IH, Greineder CF, Walsh LR, Hood ED, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Biocompatible coupling of therapeutic fusion proteins to human erythrocytes. Blood Advances. 2: 165-176. PMID 29365311 DOI: 10.1182/Bloodadvances.2017011734  0.652
2017 Greineder CF, Johnston IH, Villa CH, Gollomp K, Esmon CT, Cines DB, Poncz M, Muzykantov VR. ICAM-1-targeted thrombomodulin mitigates tissue factor-driven inflammatory thrombosis in a human endothelialized microfluidic model. Blood Advances. 1: 1452-1465. PMID 29296786 DOI: 10.1182/Bloodadvances.2017007229  0.668
2017 Kiseleva RY, Glassman PM, Greineder CF, Hood ED, Shuvaev VV, Muzykantov VR. Targeting therapeutics to endothelium: are we there yet? Drug Delivery and Translational Research. PMID 29282646 DOI: 10.1007/S13346-017-0464-6  0.675
2017 Brenner JS, Kiseleva RY, Glassman PM, Parhiz H, Greineder CF, Hood ED, Shuvaev VV, Muzykantov VR. EXPRESS: The new frontiers of the targeted interventions in the pulmonary vasculature: precision and safety. Pulmonary Circulation. 2045893217752329. PMID 29261028 DOI: 10.1177/2045893217752329  0.61
2017 Greineder CF, Villa CH, Walsh LR, Kiseleva RY, Hood ED, Khoshnejad M, Warden-Rothman R, Tsourkas A, Muzykantov VR. Site-specific modification of single-chain antibody fragments for bioconjugation and vascular immunotargeting. Bioconjugate Chemistry. PMID 29200285 DOI: 10.1021/Acs.Bioconjchem.7B00592  0.692
2017 Kiseleva R, Greineder CF, Villa CH, Hood ED, Shuvaev VV, Sun J, Chacko AM, Abraham V, DeLisser HM, Muzykantov VR. Mechanism of Collaborative Enhancement of Binding of Paired Antibodies to Distinct Epitopes of Platelet Endothelial Cell Adhesion Molecule-1. Plos One. 12: e0169537. PMID 28085903 DOI: 10.1371/Journal.Pone.0169537  0.667
2017 Brenner JS, Bhamidipati K, Glassman P, Ramakrishnan N, Jiang D, Paris AJ, Myerson JW, Pan DC, Shuvaev VV, Villa C, Hood ED, Kiseleva R, Greineder CF, Radhakrishnan R, Muzykantov VR. Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 28065731 DOI: 10.1016/J.Nano.2016.12.019  0.552
2016 Carnemolla R, Villa CH, Greineder CF, Zaitsev S, Patel KR, Kowalska MA, Atochin DN, Cines DB, Siegel DL, Esmon CT, Muzykantov VR. Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27836986 DOI: 10.1096/Fj.201600912R  0.612
2016 Greineder CF, Hood ED, Yao A, Khoshnejad M, Brenner JS, Johnston IH, Poncz M, Gottstein C, Muzykantov VR. Molecular engineering of high affinity single-chain antibody fragment for endothelial targeting of proteins and nanocarriers in rodents and humans. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26855052 DOI: 10.1016/J.Jconrel.2016.02.006  0.698
2016 Villa CH, Pan D, Johnston I, Greineder CF, Reid ME, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Coupling Therapeutics to Human Erythrocytes Demonstrates Target-Dependent Effects on Red Cell Physiology While Preserving Efficacy Blood. 128: 701-701. DOI: 10.1182/Blood.V128.22.701.701  0.665
2016 Greineder CF, Johnston I, Villa CH, Cines DB, Poncz M, Muzykantov VR. Simultaneous Replacement of Endothelial Thrombomodulin and Plasma Protein C: A Novel Therapeutic Strategy for Sepsis-Induced Disseminated Intravascular Coagulation Blood. 128: 2613-2613. DOI: 10.1182/Blood.V128.22.2613.2613  0.601
2015 Khoshnejad M, Shuvaev V, Pulsipher KW, Dai C, Hood ED, Arguiri E, Christofidou-Solomidou M, Dmochowski IJ, Greineder CF, Muzykantov VR. Vascular Accessibility of Endothelial Targeted Ferritin Nanoparticles. Bioconjugate Chemistry. PMID 26718023 DOI: 10.1021/Acs.Bioconjchem.5B00641  0.69
2015 Chacko AM, Han J, Greineder CF, Zern BJ, Mikitsh JL, Nayak M, Menon D, Johnston IH, Poncz M, Eckmann DM, Davies PF, Muzykantov VR. Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement. Acs Nano. 9: 6785-93. PMID 26153796 DOI: 10.1021/Nn505672X  0.706
2015 Greineder CF, Brenza JB, Carnemolla R, Zaitsev S, Hood ED, Pan DC, Ding BS, Esmon CT, Chacko AM, Muzykantov VR. Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 25953848 DOI: 10.1096/Fj.15-271213  0.803
2015 Myerson JW, Brenner JS, Greineder CF, Muzykantov VR. Systems approaches to design of targeted therapeutic delivery. Wiley Interdisciplinary Reviews. Systems Biology and Medicine. PMID 25946066 DOI: 10.1002/Wsbm.1304  0.667
2015 Brenner JS, Greineder C, Shuvaev V, Muzykantov V. Endothelial nanomedicine for the treatment of pulmonary disease. Expert Opinion On Drug Delivery. 12: 239-61. PMID 25394760 DOI: 10.1517/17425247.2015.961418  0.554
2015 Villa CH, Greineder CF, Johnston I, Pan D, Carnemolla R, Cines DB, Poncz M, Siegel DL, Muzykantov VR. Thrombomodulin Fusion Proteins Coupled to Human Erythrocytes Demonstrate Anti-Thrombotic and Anti-Inflammatory Activity Blood. 126: 3493-3493. DOI: 10.1182/Blood.V126.23.3493.3493  0.66
2015 Greineder CF, Johnston I, Villa CH, Cines DB, Poncz M, Muzykantov VR. A Microfluidic Model of Microvascular Inflammation: Characterization and Testing of Endothelial-Targeted Therapeutics Blood. 126: 3454-3454. DOI: 10.1182/Blood.V126.23.3454.3454  0.683
2015 Chacko AM, Han J, Greineder CF, Zern BJ, Mikitsh JL, Nayak M, Menon D, Johnston IH, Poncz M, Eckmann DM, Davies PF, Muzykantov VR. Collaborative Enhancement of Endothelial Targeting of Nanocarriers by Modulating Platelet-Endothelial Cell Adhesion Molecule-1/CD31 Epitope Engagement Acs Nano. 9: 6785-6793. DOI: 10.1021/nn505672x  0.592
2014 Howard MD, Hood ED, Greineder CF, Alferiev IS, Chorny M, Muzykantov V. Targeting to endothelial cells augments the protective effect of novel dual bioactive antioxidant/anti-inflammatory nanoparticles. Molecular Pharmaceutics. 11: 2262-70. PMID 24877560 DOI: 10.1021/Mp400677Y  0.622
2014 Hood ED, Chorny M, Greineder CF, S Alferiev I, Levy RJ, Muzykantov VR. Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation. Biomaterials. 35: 3708-15. PMID 24480537 DOI: 10.1016/J.Biomaterials.2014.01.023  0.669
2014 Howard MD, Greineder CF, Hood ED, Muzykantov VR. Endothelial targeting of liposomes encapsulating SOD/catalase mimetic EUK-134 alleviates acute pulmonary inflammation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 177: 34-41. PMID 24412573 DOI: 10.1016/J.Jconrel.2013.12.035  0.702
2013 Greineder CF, Chacko AM, Zaytsev S, Zern BJ, Carnemolla R, Hood ED, Han J, Ding BS, Esmon CT, Muzykantov VR. Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor. Plos One. 8: e80110. PMID 24244621 DOI: 10.1371/Journal.Pone.0080110  0.778
2013 Carnemolla R, Greineder CF, Chacko AM, Patel KR, Ding BS, Zaitsev S, Esmon CT, Muzykantov VR. Platelet endothelial cell adhesion molecule targeted oxidant-resistant mutant thrombomodulin fusion protein with enhanced potency in vitro and in vivo. The Journal of Pharmacology and Experimental Therapeutics. 347: 339-45. PMID 23965383 DOI: 10.1124/Jpet.113.205104  0.74
2013 Greineder CF, Howard MD, Carnemolla R, Cines DB, Muzykantov VR. Advanced drug delivery systems for antithrombotic agents. Blood. 122: 1565-75. PMID 23798715 DOI: 10.1182/Blood-2013-03-453498  0.623
2013 Zern BJ, Chacko AM, Liu J, Greineder CF, Blankemeyer ER, Radhakrishnan R, Muzykantov V. Reduction of nanoparticle avidity enhances the selectivity of vascular targeting and PET detection of pulmonary inflammation. Acs Nano. 7: 2461-9. PMID 23383962 DOI: 10.1021/Nn305773F  0.572
2012 Hood ED, Greineder CF, Dodia C, Han J, Mesaros C, Shuvaev VV, Blair IA, Fisher AB, Muzykantov VR. Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo Journal of Controlled Release. 163: 161-169. PMID 22974832 DOI: 10.1016/J.Jconrel.2012.08.031  0.626
2012 Chacko AM, Nayak M, Greineder CF, Delisser HM, Muzykantov VR. Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting. Plos One. 7: e34958. PMID 22514693 DOI: 10.1371/Journal.Pone.0034958  0.719
2012 Greineder CF, Zaytsev S, Zern B, Chacko AM, Muzykantov VR. Targeting Thrombomodulin to Endothelial ICAM-1 Rather Than PECAM-1 Allows Partnering with the Endothelial Protein C Receptor and Enhances Protection of Endothelial Barrier Function Blood. 120: 3351-3351. DOI: 10.1182/Blood.V120.21.3351.3351  0.658
2011 Greineder CF, Kohnstamm S, Ky B. Heart failure associated with sunitinib: lessons learned from animal models. Current Hypertension Reports. 13: 436-41. PMID 21826469 DOI: 10.1007/S11906-011-0225-8  0.317
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