Dannielle D. Engle, Ph.D. - Publications

Affiliations: 
2011 Biology University of California, San Diego, La Jolla, CA 
Area:
Oncology, Human Development, Cell Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liang G, Oh TG, Hah N, Tiriac H, Shi Y, Truitt ML, Antal CE, Atkins AR, Li Y, Fraser C, Ng S, Pinto AFM, Nelson DC, Estepa G, Bashi S, ... ... Engle DD, et al. Inhibiting stromal Class I HDACs curbs pancreatic cancer progression. Nature Communications. 14: 7791. PMID 38057326 DOI: 10.1038/s41467-023-42178-6  0.305
2023 Liang G, Oh TG, Hah N, Tiriac H, Shi Y, Truitt ML, Antal CE, Atkins AR, Li Y, Fraser C, Ng S, Pinto AFM, Nelson DC, Estepa G, Bashi S, ... ... Engle DD, et al. Inhibiting Stromal Class I HDACs Curbs Pancreatic Cancer Progression. Biorxiv : the Preprint Server For Biology. PMID 37745372 DOI: 10.1101/2023.09.12.557260  0.305
2023 Gulay KCM, Zhang X, Pantazopoulou V, Patel J, Esparza E, Pran Babu DS, Ogawa S, Weitz J, Ng I, Mose ES, Pu M, Engle DD, Lowy AM, Tiriac H. Dual inhibition of KRASG12D and pan-ERBB is synergistic in pancreatic ductal adenocarcinoma. Cancer Research. PMID 37378556 DOI: 10.1158/0008-5472.CAN-23-1313  0.377
2022 Lumibao JC, Tremblay JR, Hsu J, Engle DD. Altered glycosylation in pancreatic cancer and beyond. The Journal of Experimental Medicine. 219. PMID 35522218 DOI: 10.1084/jem.20211505  0.387
2020 Dasgupta A, Shukla SK, Vernucci E, King RJ, Abrego J, Mulder SE, Mullen NJ, Graves G, Buettner K, Thakur R, Murthy D, Attri KS, Wang D, Chaika NV, Pacheco CG, ... ... Engle DD, et al. SIRT1-NOX4 signaling axis regulates cancer cachexia. The Journal of Experimental Medicine. 217. PMID 32441762 DOI: 10.1084/Jem.20190745  0.434
2019 Ponz-Sarvise M, Corbo V, Tiriac H, Engle DD, Frese KK, Oni TE, Hwang CI, Öhlund D, Chio IIC, Baker LA, Filippini D, Wright K, Bapiro TE, Huang PS, Smith PD, et al. Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31492749 DOI: 10.1158/1078-0432.Ccr-19-1398  0.406
2019 Engle DD, Tiriac H, Rivera KD, Pommier A, Whalen S, Oni TE, Alagesan B, Lee EJ, Yao MA, Lucito MS, Spielman B, Da Silva B, Schoepfer C, Wright K, Creighton B, et al. The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. Science (New York, N.Y.). 364: 1156-1162. PMID 31221853 DOI: 10.1126/Science.Aaw3145  0.35
2019 Elyada E, Bolisetty M, Laise P, Flynn WF, Courtois ET, Burkhart RA, Teinor JA, Belleau P, Biffi G, Lucito MS, Sivajothi S, Armstrong TD, Engle DD, Yu KH, Hao Y, et al. Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals antigen-presenting cancer-associated fibroblasts. Cancer Discovery. PMID 31197017 DOI: 10.1158/2159-8290.Cd-19-0094  0.452
2019 Engle D, Tiriac H, Rivera K, Pommier A, Whalen S, Oni T, Alagesan B, Lee E, Yao M, Lucito M, Spielman B, Yu K, Grutzmann R, Aust D, Gimotty P, et al. Abstract PR12: The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-Pr12  0.392
2019 Tiriac H, Belleau P, Engle D, Plenker D, Deschenes A, Somerville T, Froeling F, Moffitt R, Knox J, Krasnitz A, Gallinger S, Tuveson D. Abstract C57: Organoid profiling identifies common responders to chemotherapy in pancreatic cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C57  0.476
2018 Tiriac H, Belleau P, Engle DD, Plenker D, Deschênes A, Somerville T, Froeling FEM, Burkhart RA, Denroche RE, Jang GH, Miyabayashi K, Young CM, Patel H, Ma M, LaComb JF, et al. Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery. PMID 29853643 DOI: 10.1158/2159-8290.Cd-18-0349  0.449
2018 Schmid MC, Quaranta V, Rainer C, Nielsen SR, Raymant ML, Ahmed MS, Engle DD, Taylor A, Murray T, Campbell F, Palmer DH, Tuveson DA, Mielgo A. Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer. Cancer Research. PMID 29789416 DOI: 10.1158/0008-5472.Can-17-3876  0.423
2018 Wolff RA, Wang-Gillam A, Alvarez H, Tiriac H, Engle D, Hou S, Groff AF, San Lucas A, Bernard V, Allenson K, Castillo J, Kim D, Mulu F, Huang J, Stephens B, et al. Dynamic changes during the treatment of pancreatic cancer. Oncotarget. 9: 14764-14790. PMID 29599906 DOI: 10.18632/Oncotarget.24483  0.382
2018 Engle D, Tiriac H, Pommier A, Schoepfer C, Silva BD, Yao M, Park Y, Hollingsworth MA, Tuveson D. Abstract A27: Exploring the role of glycosylation in pancreatic disease Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-A27  0.336
2017 Öhlund D, Handly-Santana A, Biffi G, Elyada E, Almeida AS, Ponz-Sarvise M, Corbo V, Oni TE, Hearn SA, Lee EJ, Chio II, Hwang CI, Tiriac H, Baker LA, Engle DD, et al. Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. The Journal of Experimental Medicine. PMID 28232471 DOI: 10.1084/Jem.20162024  0.488
2016 Ireland L, Santos A, Ahmed MS, Rainer C, Nielsen SR, Quaranta V, Weyer-Czernilofsky U, Engle DD, Perez-Mancera P, Coupland SE, Taktak AF, Bogenrieder T, Tuveson DA, Campbell F, Schmid MC, et al. Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors. Cancer Research. PMID 27742686 DOI: 10.1158/0008-5472.Can-16-1201  0.445
2016 Nielsen SR, Quaranta V, Linford A, Emeagi P, Rainer C, Santos A, Ireland L, Sakai T, Sakai K, Kim YS, Engle D, Campbell F, Palmer D, Ko JH, Tuveson DA, et al. Corrigendum: Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis. Nature Cell Biology. 18: 822. PMID 27350447 DOI: 10.1038/Ncb3377  0.402
2016 Boj SF, Hwang CI, Baker LA, Engle DD, Tuveson DA, Clevers H. Model organoids provide new research opportunities for ductal pancreatic cancer. Molecular & Cellular Oncology. 3: e1014757. PMID 27308531 DOI: 10.1080/23723556.2015.1014757  0.429
2016 Nielsen SR, Quaranta V, Linford A, Emeagi P, Rainer C, Santos A, Ireland L, Sakai T, Sakai K, Kim YS, Engle D, Campbell F, Palmer D, Ko JH, Tuveson DA, et al. Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis. Nature Cell Biology. PMID 27088855 DOI: 10.1038/Ncb3340  0.364
2016 Seifert L, Werba G, Tiwari S, Giao Ly NN, Alothman S, Alqunaibit D, Avanzi A, Barilla R, Daley D, Greco SH, Torres-Hernandez A, Pergamo M, Ochi A, Zambirinis CP, Pansari M, ... ... Engle D, et al. The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature. PMID 27049944 DOI: 10.1038/Nature17403  0.4
2016 Baker LA, Tiriac H, Corbo V, Boj SF, Hwang C, Chio IIC, Engle DD, Jager M, Ponz-Sarvise M, Spector MS, Gracanin A, Oni T, Yu KH, Boxtel Rv, Huch M, et al. Abstract B16: Using human patient-derived organoids to identify genetic dependencies in pancreatic cancer Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-B16  0.498
2016 Engle D, Tiriac H, Keith R, Ludwig M, Hwang C, Yu K, Pappin D, Tuveson D. Abstract A04: Identification of novel pancreatic cancer-specific biomarkers with organoid models Cancer Research. 76. DOI: 10.1158/1538-7445.Panca16-A04  0.445
2015 Zambirinis CP, Levie E, Nguy S, Avanzi A, Barilla R, Xu Y, Seifert L, Daley D, Greco SH, Deutsch M, Jonnadula S, Torres-Hernandez A, Tippens D, Pushalkar S, Eisenthal A, ... ... Engle DD, et al. TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. The Journal of Experimental Medicine. PMID 26481685 DOI: 10.1084/Jem.20142162  0.42
2015 Roy I, McAllister DM, Gorse E, Dixon K, Piper CT, Zimmerman NP, Getschman AE, Tsai S, Engle DD, Evans DB, Volkman BF, Kalyanaraman B, Dwinell MB. Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling. Cancer Research. 75: 3529-42. PMID 26330165 DOI: 10.1158/0008-5472.Can-14-2645  0.434
2015 Boj SF, Hwang CI, Baker LA, Chio II, Engle DD, Corbo V, Jager M, Ponz-Sarvise M, Tiriac H, Spector MS, Gracanin A, Oni T, Yu KH, van Boxtel R, Huch M, et al. Organoid models of human and mouse ductal pancreatic cancer. Cell. 160: 324-38. PMID 25557080 DOI: 10.1016/J.Cell.2014.12.021  0.462
2015 Roy I, McAllister D, Gorse E, Dixon K, Cheng G, Getschman A, Engle D, Tsai S, Tuveson D, Evans D, Volkman B, Kalyanaraman B, Dwinell M. Abstract B55: Chemokine biased agonists regulate pancreatic cancer migration and metastasis through bioenergetic signaling Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B55  0.422
2014 Sherman MH, Yu RT, Engle DD, Ding N, Atkins AR, Tiriac H, Collisson EA, Connor F, Van Dyke T, Kozlov S, Martin P, Tseng TW, Dawson DW, Donahue TR, Masamune A, et al. Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy. Cell. 159: 80-93. PMID 25259922 DOI: 10.1016/J.Cell.2014.08.007  0.574
2013 Spike BT, Engle DD, Lin JC, Kelber JA, La J, Cheung SK, Booker E, Rodewald R, Dravis C, Gray PC, Wahl GM. Abstract A136: Deconstructing stemness from the fetal mammary perspective Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A136  0.639
2012 Spike BT, Engle DD, Lin JC, Cheung SK, La J, Wahl GM. A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer. Cell Stem Cell. 10: 183-97. PMID 22305568 DOI: 10.1016/J.Stem.2011.12.018  0.642
2012 Wahl G, Spike B, Engle D, Lin J, Cheung S, La J. Stem cells, cancer, and cancer stem cells F1000research. 3. DOI: 10.7490/F1000Research.1089958.1  0.631
2012 Spike BT, Engle DD, Lin JC, La J, Cheung SK, Wahl GM. Abstract 1015: Mammary stem cells increase late in embryogenesis, facilitating their characterization and revealing links to breast cancer Cancer Research. 72: 1015-1015. DOI: 10.1158/1538-7445.Am2012-1015  0.642
2011 Wang YV, Leblanc M, Fox N, Mao JH, Tinkum KL, Krummel K, Engle D, Piwnica-Worms D, Piwnica-Worms H, Balmain A, Kaushansky K, Wahl GM. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes & Development. 25: 1426-38. PMID 21724834 DOI: 10.1101/Gad.2024411  0.565
2010 Engle D, Lin J, Spike B, Cheung S, Wahl G. Abstract PD02-02: Characterization of Mammary Stem Cells during Embryogenesis Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Pd02-02  0.34
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