| Year |
Citation |
Score |
| 2012 |
Hasan NM, Longacre MJ, Stoker SW, Kendrick MA, Druckenbrod NR, Laychock SG, Mastrandrea LD, MacDonald MJ. Sphingosine kinase 1 knockdown reduces insulin synthesis and secretion in a rat insulinoma cell line. Archives of Biochemistry and Biophysics. 518: 23-30. PMID 22155656 DOI: 10.1016/J.Abb.2011.11.016 |
0.478 |
|
| 2011 |
Lock LT, Laychock SG, Tzanakakis ES. Pseudoislets in stirred-suspension culture exhibit enhanced cell survival, propagation and insulin secretion. Journal of Biotechnology. 151: 278-86. PMID 21185337 DOI: 10.1016/J.Jbiotec.2010.12.015 |
0.421 |
|
| 2011 |
You H, Laychock SG. Long-term treatment with atrial natriuretic peptide inhibits ATP production and insulin secretion in rat pancreatic islets. American Journal of Physiology. Endocrinology and Metabolism. 300: E435-44. PMID 20959527 DOI: 10.1152/Ajpendo.00398.2010 |
0.664 |
|
| 2010 |
Mastrandrea LD, Sessanna SM, Del Toro A, Laychock SG. ATP-independent glucose stimulation of sphingosine kinase in rat pancreatic islets. Journal of Lipid Research. 51: 2171-80. PMID 20371493 DOI: 10.1194/Jlr.M000802 |
0.536 |
|
| 2009 |
You H, Laychock SG. Atrial natriuretic peptide promotes pancreatic islet beta-cell growth and Akt/Foxo1a/cyclin D2 signaling. Endocrinology. 150: 5455-65. PMID 19837876 DOI: 10.1210/En.2009-0468 |
0.628 |
|
| 2008 |
Tian J, Lei P, Laychock SG, Andreadis ST. Regulated insulin delivery from human epidermal cells reverses hyperglycemia. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1146-53. PMID 18431361 DOI: 10.1038/Mt.2008.79 |
0.448 |
|
| 2007 |
Lei P, Ogunade A, Kirkwood KL, Laychock SG, Andreadis ST. Efficient production of bioactive insulin from human epidermal keratinocytes and tissue-engineered skin substitutes: implications for treatment of diabetes. Tissue Engineering. 13: 2119-31. PMID 17518716 DOI: 10.1089/Ten.2006.0210 |
0.423 |
|
| 2006 |
Laychock SG, Sessanna SM, Lin MH, Mastrandrea LD. Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells. Endocrinology. 147: 4705-12. PMID 16794003 DOI: 10.1210/En.2006-0456 |
0.414 |
|
| 2005 |
Mastrandrea LD, Sessanna SM, Laychock SG. Sphingosine kinase activity and sphingosine-1 phosphate production in rat pancreatic islets and INS-1 cells: response to cytokines. Diabetes. 54: 1429-36. PMID 15855330 DOI: 10.2337/Diabetes.54.5.1429 |
0.379 |
|
| 2003 |
Laychock SG, Tian Y, Sessanna SM. Endothelial differentiation gene receptors in pancreatic islets and INS-1 cells. Diabetes. 52: 1986-93. PMID 12882914 DOI: 10.2337/Diabetes.52.8.1986 |
0.512 |
|
| 2003 |
Tian Y, Laychock SG. Prolactin regulates adenylyl cyclase and insulin secretion in rat pancreatic islets. Molecular and Cellular Endocrinology. 204: 75-84. PMID 12850283 DOI: 10.1016/S0303-7207(03)00126-6 |
0.527 |
|
| 2003 |
Takeuchi T, Aletta JM, Laychock SG, Tian Y, Rubin RP. Role of nerve growth factor in the regulation of parotid cell differentiation induced by rat serum. Biochemical Pharmacology. 65: 1507-13. PMID 12732363 DOI: 10.1016/S0006-2952(03)00116-3 |
0.332 |
|
| 2003 |
Srinivasan M, Laychock SG, Hill DJ, Patel MS. Neonatal nutrition: metabolic programming of pancreatic islets and obesity. Experimental Biology and Medicine (Maywood, N.J.). 228: 15-23. PMID 12524468 DOI: 10.1177/153537020322800102 |
0.336 |
|
| 2003 |
Lee BS, Sessanna S, Laychock SG, Rubin RP. Expression and cellular localization of a modified type 1 ryanodine receptor and L-type channel proteins in non-muscle cells. The Journal of Membrane Biology. 189: 181-90. PMID 12395283 DOI: 10.1007/S00232-002-1012-X |
0.314 |
|
| 2001 |
Tian Y, Laychock SG. Protein kinase C and calcium regulation of adenylyl cyclase in isolated rat pancreatic islets. Diabetes. 50: 2505-13. PMID 11679428 DOI: 10.2337/Diabetes.50.11.2505 |
0.473 |
|
| 2001 |
Lee B, Gai W, Laychock SG. Proteasomal activation mediates down-regulation of inositol 1,4,5-trisphosphate receptor and calcium mobilization in rat pancreatic islets. Endocrinology. 142: 1744-51. PMID 11316737 DOI: 10.1210/Endo.142.5.8150 |
0.538 |
|
| 2001 |
Lee B, Srinivasan M, Aalinkeel R, Patel MS, Laychock SG. Mitochondrial-encoded gene regulation in rat pancreatic islets. Metabolism: Clinical and Experimental. 50: 200-6. PMID 11229430 DOI: 10.1053/Meta.2001.17714 |
0.369 |
|
| 2001 |
Lee B, Laychock SG. Inositol 1,4,5-trisphosphate receptor isoform expression in mouse pancreatic islets: effects of carbachol. Biochemical Pharmacology. 61: 327-36. PMID 11172737 DOI: 10.1016/S0006-2952(00)00559-1 |
0.452 |
|
| 2001 |
Srinivasan M, Aalinkeel R, Song F, Lee B, Laychock SG, Patel MS. Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula. American Journal of Physiology. Endocrinology and Metabolism. 279: E1347-57. PMID 11093923 DOI: 10.1152/Ajpendo.2000.279.6.E1347 |
0.532 |
|
| 2000 |
Laychock SG, Duzen J, Simpkins CO. Metallothionein induction in islets of Langerhans and insulinoma cells. Molecular and Cellular Endocrinology. 165: 179-87. PMID 10940496 DOI: 10.1016/S0303-7207(00)00247-1 |
0.427 |
|
| 2000 |
Lee B, Laychock SG. Regulation of inositol trisphosphate receptor isoform expression in glucose-desensitized rat pancreatic islets: role of cyclic adenosine 3',5'-monophosphate and calcium. Endocrinology. 141: 1394-402. PMID 10746643 DOI: 10.1210/Endo.141.4.7421 |
0.448 |
|
| 2000 |
Aalinkeel R, Srinivasan M, Kalhan SC, Laychock SG, Patel MS. A dietary intervention (high carbohydrate) during the neonatal period causes islet dysfunction in rats. The American Journal of Physiology. 277: E1061-9. PMID 10600796 DOI: 10.1152/Ajpendo.1999.277.6.E1061 |
0.479 |
|
| 1999 |
Lee B, Jonas JC, Weir GC, Laychock SG. Glucose regulates expression of inositol 1,4,5-trisphosphate receptor isoforms in isolated rat pancreatic islets. Endocrinology. 140: 2173-82. PMID 10218969 DOI: 10.1210/Endo.140.5.6738 |
0.43 |
|
| 1999 |
Laychock SG. Rat pancreatic islet and RINm5F cell responses to epiandrosterone, dehydroepiandrosterone and interleukin-1 beta. Biochemical Pharmacology. 55: 1453-64. PMID 10076538 DOI: 10.1016/S0006-2952(97)00666-7 |
0.405 |
|
| 1998 |
Ye J, Laychock SG. A Protective Role for Heme Oxygenase Expression in Pancreatic Islets Exposed to Interleukin-1β* * This work was supported by NIH Grant DK-25705 (to S.G.L.). Endocrinology. 139: 4155-4163. PMID 28200371 DOI: 10.1210/Endo.139.10.6244 |
0.376 |
|
| 1998 |
Lee B, Bradford PG, Laychock SG. Characterization of inositol 1,4,5-trisphosphate receptor isoform mRNA expression and regulation in rat pancreatic islets, RINm5F cells and betaHC9 cells. Journal of Molecular Endocrinology. 21: 31-9. PMID 9723861 DOI: 10.1677/Jme.0.0210031 |
0.449 |
|
| 1997 |
Lee B, Laychock SG. Atrial natriuretic peptide and cyclic nucleotides affect glucose-induced Ca2+ responses in single pancreatic islet beta-cells: correlation with (Ca[2+] + Mg2+)-ATPase activity. Diabetes. 46: 1312-8. PMID 9231656 DOI: 10.2337/Diab.46.8.1312 |
0.416 |
|
| 1996 |
Laychock SG. Modulation of glyceraldehyde 3-phosphate dehydrogenase activity in isolated pancreatic islets. Biochemical Pharmacology. 52: 793-9. PMID 8765477 DOI: 10.1016/0006-2952(96)00391-7 |
0.453 |
|
| 1996 |
Laychock SG, Bauer AL. Epiandrosterone and dehydroepiandrosterone affect glucose oxidation and interleukin-1 beta effects in pancreatic islets. Endocrinology. 137: 3375-85. PMID 8754764 DOI: 10.1210/Endo.137.8.8754764 |
0.485 |
|
| 1996 |
Laychock SG. Impaired cyclic AMP response to stimuli in glucose-desensitized rat pancreatic islets. Molecular and Cellular Endocrinology. 113: 19-28. PMID 8674810 DOI: 10.1016/0303-7207(95)03606-8 |
0.506 |
|
| 1995 |
Laychock SG, Vadlamudi S, Patel MS. Neonatal rat dietary carbohydrate affects pancreatic islet insulin secretion in adults and progeny. The American Journal of Physiology. 269: E739-44. PMID 7485489 DOI: 10.1152/Ajpendo.1995.269.4.E739 |
0.486 |
|
| 1994 |
Laychock SG. Sp-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-cyclic monophosphorothioate is a potent stimulus for insulin release. Endocrine Research. 19: 113-22. PMID 8287829 DOI: 10.3109/07435809309033018 |
0.381 |
|
| 1994 |
Desole MS, Kim WK, Rabin RA, Laychock SG. Nitric oxide reduces depolarization-induced calcium influx in PC12 cells by a cyclic GMP-mediated mechanism. Neuropharmacology. 33: 193-8. PMID 8035903 DOI: 10.1016/0028-3908(94)90007-8 |
0.388 |
|
| 1993 |
Xia M, Laychock SG. Insulin secretion, myo-inositol transport, and Na+-K+-ATPase in glucose-desensitized rat islets Diabetes. 42: 1392-1400. PMID 8397125 DOI: 10.2337/Diab.42.10.1392 |
0.515 |
|
| 1992 |
Khalaf LJ, Laychock SG. Phosphatidylinositol availability and polyphosphoinositide synthesis in pancreatic islet cell membranes. Biochemical Pharmacology. 43: 1303-10. PMID 1314058 DOI: 10.1016/0006-2952(92)90507-F |
0.493 |
|
| 1991 |
Laychock SG. Glucose metabolism, second messengers and insulin secretion. Life Sciences. 47: 2307-16. PMID 2175823 DOI: 10.1016/0024-3205(90)90269-W |
0.486 |
|
| 1991 |
Rubin RP, Withiam-Leitch M, Laychock SG. Modulation of phospholipase A2 activity in zymogen granule membranes by GTP[S]; evidence for GTP-binding protein regulation. Biochemical and Biophysical Research Communications. 177: 22-6. PMID 1904217 DOI: 10.1016/0006-291X(91)91942-6 |
0.305 |
|
| 1991 |
Laychock SG, Modica ME, Cavanaugh CT. L-arginine stimulates cyclic guanosine 3',5'-monophosphate formation in rat islets of Langerhans and RINm5F insulinoma cells: evidence for L-arginine:nitric oxide synthase. Endocrinology. 129: 3043-52. PMID 1683279 DOI: 10.1210/Endo-129-6-3043 |
0.461 |
|
| 1991 |
Chang MC, Berkery D, Laychock SG, Schuel H. Reduction of the fertilizing capacity of sea urchin sperm by cannabinoids derived from marihuana. III. Activation of phospholipase A2 in sperm homogenate by delta 9-tetrahydrocannabinol. Biochemical Pharmacology. 42: 899-904. PMID 1651081 DOI: 10.1016/0006-2952(91)90051-6 |
0.308 |
|
| 1991 |
Conway BR, Laychock SG, Rubin RP. Comparative effects of epidermal growth factor and carbachol on phosphoinositide synthesis and breakdown in pancreatic acinar cells. Biochemical and Biophysical Research Communications. 178: 780-5. PMID 1650199 DOI: 10.1016/0006-291X(91)90176-8 |
0.34 |
|
| 1990 |
Rubin RP, Thompson RH, Laychock SG. Characterization of phospholipase A2 and acyltransferase activities in purified zymogen granule membranes. Biochimica Et Biophysica Acta. 1045: 245-51. PMID 2386797 DOI: 10.1016/0005-2760(90)90127-J |
0.317 |
|
| 1989 |
Morgan RO, Laychock SG. Biosynthesis of peptidyl leukotrienes and other lipoxygenase products by rat pancreatic islets. Comparison with macrophages and neutrophils. Prostaglandins. 35: 609-23. PMID 3150114 DOI: 10.1016/0090-6980(88)90035-4 |
0.433 |
|
| 1989 |
Laychock SG. Prostaglandin E2 and alpha 2 adrenoceptor agonists inhibit the pentose phosphate shunt in pancreatic islets. Archives of Biochemistry and Biophysics. 269: 354-8. PMID 2563646 DOI: 10.1016/0003-9861(89)90117-3 |
0.458 |
|
| 1989 |
Laychock SG. Coordinate interactions of cyclic nucleotide and phospholipid metabolizing pathways in calcium-dependent cellular processes. Current Topics in Cellular Regulation. 30: 203-242. PMID 2559830 DOI: 10.1016/B978-0-12-152830-0.50009-8 |
0.372 |
|
| 1989 |
Laychock SG. Prostaglandin E2 inhibits phosphoinositide metabolism in isolated pancreatic islets. The Biochemical Journal. 260: 291-4. PMID 2549955 DOI: 10.1042/Bj2600291 |
0.478 |
|
| 1989 |
Laychock SG, Bilgin S. Calcium mobilization, prostaglandin E2 and α2-adrenoceptor modulation of glucose utilization and insulin secretion in pancreatic islets Biochemical Pharmacology. 38: 2511-2520. PMID 2547383 DOI: 10.1016/0006-2952(89)90096-8 |
0.528 |
|
| 1989 |
Chaudhry A, Conway BR, Laychock SG, Rubin RP. Analysis of the regulation of phosphatidylinositol-4,5-bisphosphate synthesis by arachidonic acid in exocrine pancreas. Archives of Biochemistry and Biophysics. 272: 488-95. PMID 2546502 DOI: 10.1016/0003-9861(89)90244-0 |
0.339 |
|
| 1988 |
Hoffman JM, Laychock SG. Choline turnover in phosphatidylcholine of pancreatic islets. Implications for CDP-choline pathway Diabetes. 37: 1489-1498. PMID 2846391 DOI: 10.2337/Diab.37.11.1489 |
0.539 |
|
| 1987 |
Laychock SG, Bilgin S. Alpha 2-adrenergic inhibition of pancreatic islet glucose utilization is mediated by an inhibitory guanine nucleotide regulatory protein. Febs Letters. 218: 7-10. PMID 2885223 DOI: 10.1016/0014-5793(87)81007-4 |
0.452 |
|
| 1987 |
Laychock SG. Effects of guanosine 3',5'-monophosphate on glucose utilization in isolated islets of Langerhans. Endocrinology. 120: 517-24. PMID 2433125 DOI: 10.1210/Endo-120-2-517 |
0.481 |
|
| 1986 |
Laychock SG, Hoffman JM, Meisel E, Bilgin S. Pancreatic islet arachidonic acid turnover and metabolism and insulin release in response to delta-9-tetrahydrocannabinol Biochemical Pharmacology. 35: 2003-2008. PMID 3013206 DOI: 10.1016/0006-2952(86)90733-1 |
0.544 |
|
| 1985 |
Laychock SG. Effects of hydroxyeicosatetraenoic acids on fatty acid esterification in phospholipids and insulin secretion in pancreatic islets. Endocrinology. 117: 1011-9. PMID 3926463 DOI: 10.1210/Endo-117-3-1011 |
0.507 |
|
| 1984 |
Kelly KL, Laychock SG. Activity of prostaglandin biosynthetic pathways in rat pancreatic islets. Prostaglandins. 27: 925-38. PMID 6435185 DOI: 10.1016/S0090-6980(84)80011-8 |
0.531 |
|
| 1984 |
Laychock SG. Identification and metabolism of polyphosphoinositides in isolated islets of Langerhans. The Biochemical Journal. 216: 101-6. PMID 6316930 DOI: 10.1042/Bj2160101 |
0.461 |
|
| 1984 |
Laychock SG. Mediation of insulin release by cGMP and cAMP in a starved animal model. Molecular and Cellular Endocrinology. 32: 157-70. PMID 6315506 DOI: 10.1016/0303-7207(83)90079-5 |
0.535 |
|
| 1983 |
Laychock SG. Fatty acid incorporation into phospholipids of isolated pancreatic islets of the rat. Relationship to insulin release. Diabetes. 32: 6-13. PMID 6336703 DOI: 10.2337/Diab.32.1.6 |
0.521 |
|
| 1982 |
Laychock SG. Phospholipase A2 activity in pancreatic islets is calcium-dependent and stimulated by glucose. Cell Calcium. 3: 43-54. PMID 7049396 DOI: 10.1016/0143-4160(82)90036-7 |
0.456 |
|
| 1982 |
Garcia R, Laychock SG, Rubin RP. Inhibition of dibutyryl cyclic AMP induced steroidogenesis in rat adrenocortical cells by the putative calcium antagonist TMB-8. Journal of Steroid Biochemistry. 16: 317-22. PMID 6281580 DOI: 10.1016/0022-4731(82)90183-2 |
0.345 |
|
| 1981 |
Kelly KL, Laychock SG. Prostaglandin synthesis and metabolism in isolated pancreatic islets of the rat. Prostaglandins. 21: 759-69. PMID 6803305 DOI: 10.1016/0090-6980(81)90233-1 |
0.385 |
|
| 1981 |
Laychock SG. Evidence for guanosine 3',5'-monophosphate as a putative mediator of insulin secretion from isolated rat islets. Endocrinology. 108: 1197-205. PMID 6258897 DOI: 10.1210/Endo-108-4-1197 |
0.522 |
|
| 1980 |
Laychock SG, Walker L. Evidence for 6-keto-PGF1 alpha in adrenal cortex of the rat and effects of 6-keto-PGF1 alpha and PGI2 on adrenal cAMP levels and steroidogenesis. Prostaglandins. 18: 793-811. PMID 232283 DOI: 10.1016/0090-6980(79)90099-6 |
0.354 |
|
| 1980 |
Laychock SG, Harada E, Rubin RP. Isoproterenol and nucleotide induced stimulation of Ca2+ uptake by microsomal fractions from kidney and isolated glomeruli. Biochemical Pharmacology. 28: 3205-11. PMID 230846 DOI: 10.1016/0006-2952(79)90063-7 |
0.346 |
|
| 1980 |
Rubin R, Shen J, Laychock S. Evidence for the mobilization of cellular calcium by prostacyclin in cat adrenocortical cells: The effect of TMB-8 Cell Calcium. 1: 391-400. DOI: 10.1016/0143-4160(80)90041-X |
0.338 |
|
| 1979 |
Harada E, Laychock SG, Rubin RP. Parathyroid hormone induced stimulation of calcium uptake by renal microsomes. Biochemical and Biophysical Research Communications. 84: 396-402. PMID 718689 DOI: 10.1016/0006-291X(78)90183-3 |
0.343 |
|
| 1978 |
Laychock SG, Landon EJ, Hardman JG. The effect of adrenocorticotropin and nucleotides on Ca2+ uptake in adrenal cortical microsomal vesicles. Endocrinology. 103: 2198-206. PMID 218805 DOI: 10.1210/Endo-103-6-2198 |
0.402 |
|
| 1978 |
Laychock SG, Shen JC, Carmines EL, Rubin RP. The effect of corticotropin on phospholipid metabolism in isolated adrenocortical cells Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 528: 355-363. PMID 205250 DOI: 10.1016/0005-2760(78)90024-3 |
0.386 |
|
| 1978 |
Laychock SG, Rubin RP. Regulation of steroidogenesis and prostaglandin formation in isolated adrenocortical cells: the effects of pregnenolone and cycloheximide. Journal of Steroid Biochemistry. 8: 663-7. PMID 201802 DOI: 10.1016/0022-4731(77)90294-1 |
0.396 |
|
| 1977 |
Rubin RP, Laychock SG, End DW. On the role of cyclic AMP and cyclic GMP in steroid production by bovine cortical cells. Biochimica Et Biophysica Acta. 496: 329-38. PMID 189838 DOI: 10.1016/0304-4165(77)90315-4 |
0.387 |
|
| 1977 |
Gemmell RT, Laychock SG, Rubin RP. Ultrastructural and biochemical evidence for a steroid-containing secretory organelle in the perfused cat adrenal gland. The Journal of Cell Biology. 72: 209-15. PMID 187604 DOI: 10.1083/Jcb.72.1.209 |
0.386 |
|
| 1977 |
Laychock SG, Warner W, Rubin RP. Further studies on the mechanisms controlling prostaglandin biosynthesis in the cat adrenal cortex: the role of calcium and cyclic AMP. Endocrinology. 100: 74-81. PMID 187409 DOI: 10.1210/Endo-100-1-74 |
0.373 |
|
| 1977 |
Laychock SG, Franson RC, Weglicki WB, Rubin RP. Identification and partial characterization of phospholipases in isolated adrenocortical cells. The effects of synacthen [corticotropin-(1--24)-tetracosapeptide] and calcium ions. The Biochemical Journal. 164: 753-6. PMID 19012 DOI: 10.1042/Bj1640753 |
0.382 |
|
| 1976 |
Laychock SG, Rubin RP. Radioimmunoassay measurement of ACTH-facilitated PGE2 and PGF2alpha release from isolated cat adrenocortical cells. Prostaglandins. 11: 753-67. PMID 183238 DOI: 10.1016/0090-6980(76)90075-7 |
0.378 |
|
| 1976 |
Laychock SG, Rubin RP. Indomethacin-induced alterations in corticosteroid and prostaglandin release by isolated adrenocortical cells of the cat. British Journal of Pharmacology. 57: 273-8. PMID 181110 DOI: 10.1111/J.1476-5381.1976.Tb07477.X |
0.344 |
|
| 1976 |
Laychock SG, Rubin RP. ACTH-induced prostaglandin biosynthesis from 3H-arachidonic acid by adrenocortical cells. Prostaglandins. 10: 529-40. PMID 172981 DOI: 10.1016/0090-6980(75)90135-5 |
0.359 |
|
| 1975 |
Laychock SG, Rubin RP. Isolation of ACTH-induced protein from adrenal perfusate. Steroids. 24: 177-84. PMID 4370716 DOI: 10.1016/0039-128X(74)90100-7 |
0.317 |
|
| 1974 |
Rubin RP, Sheid B, McCauley R, Laychock SG. ACTH-induced protein release from the perfused cat adrenal gland: evidence for exocytosis? Endocrinology. 95: 370-8. PMID 4368443 DOI: 10.1210/Endo-95-2-370 |
0.357 |
|
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