Ivelin S. Georgiev, Ph.D. - Publications

Affiliations: 
2009 Computer Science Duke University, Durham, NC 
Area:
Computer Science, Bioinformatics Biology

117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Murji AA, Qin JS, Hermanus T, Morris L, Georgiev IS. Elicitation of Neutralizing Antibody Responses to HIV-1 Immunization with Nanoparticle Vaccine Platforms. Viruses. 13. PMID 34372503 DOI: 10.3390/v13071296  1
2021 Kramer KJ, Wilfong EM, Voss K, Barone SM, Shiakolas AR, Raju N, Roe CE, Suryadevara N, Walker L, Wall SC, Paulo A, Schaefer S, Dahunsi D, Westlake CS, Crowe JE, ... ... Georgiev IS, et al. Single-Cell Profiling of the Antigen-Specific Response to BNT162b2 SARS-CoV-2 RNA Vaccine. Biorxiv : the Preprint Server For Biology. PMID 34341788 DOI: 10.1101/2021.07.28.453981  1
2021 Shiakolas AR, Johnson N, Kramer KJ, Suryadevara N, Wrapp D, Periasamy S, Pilewski KA, Raju N, Nargi R, Sutton RE, Walker L, Crowe JE, Bukreyev A, Carnahan RH, McLellan JS, ... Georgiev IS, et al. Efficient discovery of potently neutralizing SARS-CoV-2 antibodies using LIBRA-seq with ligand blocking. Biorxiv : the Preprint Server For Biology. PMID 34100018 DOI: 10.1101/2021.06.02.446813  1
2021 Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, ... ... Georgiev IS, et al. Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions. Cell Reports. Medicine. 100313. PMID 34056628 DOI: 10.1016/j.xcrm.2021.100313  1
2021 Townsley SM, Donofrio GC, Jian N, Leggat DJ, Dussupt V, Mendez-Rivera L, Eller LA, Cofer L, Choe M, Ehrenberg PK, Geretz A, Gift S, Grande R, Lee A, Peterson C, ... ... Georgiev IS, et al. B cell engagement with HIV-1 founder virus envelope predicts development of broadly neutralizing antibodies. Cell Host & Microbe. PMID 33662277 DOI: 10.1016/j.chom.2021.01.016  1
2021 Mdluli T, Jian N, Slike B, Paquin-Proulx D, Donofrio G, Alrubayyi A, Gift S, Grande R, Bryson M, Lee A, Dussupt V, Mendez-Rivera L, Sanders-Buell E, Chenine AL, Tran U, ... ... Georgiev IS, et al. Correction: RV144 HIV-1 vaccination impacts post-infection antibody responses. Plos Pathogens. 17: e1009386. PMID 33651828 DOI: 10.1371/journal.ppat.1009386  1
2020 Shiakolas AR, Kramer KJ, Wrapp D, Richardson SI, Schäfer A, Wall S, Wang N, Janowska K, Pilewski KA, Venkat R, Parks R, Manamela NP, Raju N, Fechter EF, Holt CM, ... ... Georgiev IS, et al. Cross-reactive coronavirus antibodies with diverse epitope specificities and extra-neutralization functions. Biorxiv : the Preprint Server For Biology. PMID 33398266 DOI: 10.1101/2020.12.20.414748  1
2020 Mdluli T, Jian N, Slike B, Paquin-Proulx D, Donofrio G, Alrubayyi A, Gift S, Grande R, Bryson M, Lee A, Dussupt V, Mendez-Riveria L, Sanders-Buell E, Chenine AL, Tran U, ... ... Georgiev IS, et al. RV144 HIV-1 vaccination impacts post-infection antibody responses. Plos Pathogens. 16: e1009101. PMID 33290394 DOI: 10.1371/journal.ppat.1009101  1
2020 Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe JE. Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Science Immunology. 5. PMID 32620559 DOI: 10.1126/Sciimmunol.Aba4902  1
2020 Ndlovu B, Gounder K, Muema D, Raju N, Hermanus T, Mthethwa Q, Robertson K, Walker BD, Georgiev IS, Morris L, Moore PL, Ndung'u T. Envelope characteristics in individuals who developed neutralizing antibodies targeting different epitopes in HIV-1 subtype C infection. Virology. 546: 1-12. PMID 32275203 DOI: 10.1016/J.Virol.2020.03.003  1
2020 Dussupt V, Sankhala RS, Gromowski GD, Donofrio G, De La Barrera RA, Larocca RA, Zaky W, Mendez-Rivera L, Choe M, Davidson E, McCracken MK, Brien JD, Abbink P, Bai H, Bryan AL, ... ... Georgiev IS, et al. Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nature Medicine. PMID 32015557 DOI: 10.1038/S41591-019-0746-2  1
2020 Keating CL, Kuhn E, Bals J, Cocco AR, Yousif AS, Matysiak C, Sangesland M, Ronsard L, Smoot M, Barcamonte Moreno T, Okonkwo V, Setliff I, Georgiev I, Balazs AB, Carr SA, et al. Spontaneous glycan reattachment following N-glycanase treatment of influenza and HIV vaccine antigens. Journal of Proteome Research. PMID 31913636 DOI: 10.1021/Acs.Jproteome.9B00620  1
2019 Joyce MG, Bao A, Chen M, Georgiev IS, Ou L, Bylund T, Druz A, Kong WP, Peng D, Rundlet EJ, Van Galen JG, Wang S, Yang Y, Zhang B, Chuang GY, et al. Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B. Pathogens & Immunity. 4: 294-323. PMID 31893251 DOI: 10.20411/pai.v4i2.338  1
2019 Setliff I, Shiakolas AR, Pilewski KA, Murji AA, Mapengo RE, Janowska K, Richardson S, Oosthuysen C, Raju N, Ronsard L, Kanekiyo M, Qin JS, Kramer KJ, Greenplate AR, McDonnell WJ, ... ... Georgiev IS, et al. High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity. Cell. PMID 31787378 DOI: 10.1016/J.Cell.2019.11.003  1
2019 Redd AD, Doria-Rose NA, Weiner JA, Nason M, Seivers M, Schmidt SD, Laeyendecker O, Martens C, Bruno D, Keele BF, Raju N, Georgiev IS, Lamers SL, Astemborski J, Kirk GD, et al. Longitudinal antibody responses in people who inject drugs infected with similar HIV strains. The Journal of Infectious Diseases. PMID 31581292 DOI: 10.1093/Infdis/Jiz503  1
2019 Schoofs T, Barnes CO, Suh-Toma N, Golijanin J, Schommers P, Gruell H, West AP, Bach F, Lee YE, Nogueira L, Georgiev IS, Bailer RT, Czartoski J, Mascola JR, Seaman MS, et al. Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity. PMID 31126879 DOI: 10.1016/J.Immuni.2019.04.014  1
2019 Kanekiyo M, Joyce MG, Gillespie RA, Gallagher JR, Andrews SF, Yassine HM, Wheatley AK, Fisher BE, Ambrozak DR, Creanga A, Leung K, Yang ES, Boyoglu-Barnum S, Georgiev IS, Tsybovsky Y, et al. Author Correction: Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nature Immunology. PMID 30980067 DOI: 10.1038/S41590-019-0395-0  1
2019 Krebs SJ, Kwon YD, Schramm CA, Law WH, Donofrio G, Zhou KH, Gift S, Dussupt V, Georgiev IS, Schätzle S, McDaniel JR, Lai YT, Sastry M, Zhang B, Jarosinski MC, et al. Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity. PMID 30876875 DOI: 10.1016/J.Immuni.2019.02.008  1
2019 Raju N, Setliff I, Georgiev IS. NFPws: a web server for delineating broadly neutralizing antibody specificities from serum HIV-1 neutralization data. Bioinformatics (Oxford, England). PMID 30838378 DOI: 10.1093/Bioinformatics/Btz097  1
2019 Kanekiyo M, Joyce MG, Gillespie RA, Gallagher JR, Andrews SF, Yassine HM, Wheatley AK, Fisher BE, Ambrozak DR, Creanga A, Leung K, Yang ES, Boyoglu-Barnum S, Georgiev IS, Tsybovsky Y, et al. Mosaic nanoparticle display of diverse influenza virus hemagglutinins elicits broad B cell responses. Nature Immunology. PMID 30742080 DOI: 10.1038/S41590-018-0305-X  1
2018 Borst AJ, Weidle CE, Gray MD, Frenz B, Snijder J, Joyce MG, Georgiev IS, Stewart-Jones GB, Kwong PD, McGuire AT, DiMaio F, Stamatatos L, Pancera M, Veesler D. Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Elife. 7. PMID 30403372 DOI: 10.2210/Pdb6Mft/Pdb  1
2018 Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, ... ... Georgiev IS, et al. Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nature Medicine. PMID 29867235 DOI: 10.1038/s41591-018-0042-6  1
2018 Setliff I, McDonnell WJ, Raju N, Bombardi RG, Murji AA, Scheepers C, Ziki R, Mynhardt C, Shepherd BE, Mamchak AA, Garrett N, Karim SA, Mallal SA, Crowe JE, Morris L, ... Georgiev IS, et al. Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host & Microbe. PMID 29861170 DOI: 10.1016/J.Chom.2018.05.001  1
2018 González N, McKee K, Lynch RM, Georgiev IS, Jimenez L, Grau E, Yuste E, Kwong PD, Mascola JR, Alcamí J. Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors. Plos One. 13: e0193773. PMID 29558468 DOI: 10.1371/Journal.Pone.0193773  1
2018 Zhou T, Zheng A, Baxa U, Chuang GY, Georgiev IS, Kong R, O'Dell S, Shahzad-Ul-Hussan S, Shen CH, Tsybovsky Y, Bailer RT, Gift SK, Louder MK, McKee K, Rawi R, et al. A Neutralizing Antibody Recognizing Primarily N-linked Glycan Targets the Silent Face of the HIV Envelope. Immunity. PMID 29548671 DOI: 10.1016/J.Immuni.2018.02.013  1
2018 Georgiev IS, Joyce MG, Chen RE, Leung K, McKee K, Druz A, Van Galen JG, Kanekiyo M, Tsybovsky Y, Yang ES, Yang Y, Acharya P, Pancera M, Thomas PV, Wanninger T, et al. Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens. Acs Infectious Diseases. PMID 29451984 DOI: 10.1021/Acsinfecdis.7B00192  1
2018 Kwon YD, Chuang GY, Zhang B, Bailer RT, Doria-Rose NA, Gindin TS, Lin B, Louder MK, McKee K, O'Dell S, Pegu A, Schmidt SD, Asokan M, Chen X, Choe M, ... Georgiev IS, et al. Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody. Cell Reports. 22: 1798-1809. PMID 29444432 DOI: 10.1016/J.Celrep.2018.01.023  1
2018 Borst AJ, Weidle CE, Gray MD, Frenz B, Snijder J, Joyce MG, Georgiev IS, Stewart-Jones GB, Kwong PD, McGuire AT, DiMaio F, Stamatatos L, Pancera M, Veesler D. Author response: Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core Elife. DOI: 10.7554/Elife.37688.042  1
2018 Xu K, Acharya P, Kong R, Cheng C, Chuang GY, Liu K, Louder MK, O'Dell S, Rawi R, Sastry M, Shen CH, Zhang B, Zhou T, Asokan M, Bailer RT, ... ... Georgiev IS, et al. Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1. Nature Medicine. 24: 857-867. DOI: 10.2210/Pdb6Cdp/Pdb  1
2017 Saunders KO, Verkoczy LK, Jiang C, Zhang J, Parks R, Chen H, Housman M, Bouton-Verville H, Shen X, Trama AM, Scearce R, Sutherland L, Santra S, Newman A, Eaton A, ... ... Georgiev IS, et al. Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models. Cell Reports. 21: 3681-3690. PMID 29281818 DOI: 10.1016/J.Celrep.2017.12.028  1
2017 Joyce MG, Georgiev IS, Yang Y, Druz A, Geng H, Chuang GY, Kwon YD, Pancera M, Rawi R, Sastry M, Stewart-Jones GBE, Zheng A, Zhou T, Choe M, Van Galen JG, et al. Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains. Cell Reports. 21: 2992-3002. PMID 29212041 DOI: 10.1016/J.Celrep.2017.11.016  1
2017 Koethe JR, McDonnell W, Kennedy A, Abana CO, Pilkinton M, Setliff I, Georgiev I, Barnett L, Hager CC, Smith R, Kalams SA, Hasty A, Mallal S. Adipose Tissue is Enriched for Activated and Late-differentiated CD8+ T cells, and Shows Distinct CD8+ Receptor Usage, Compared to Blood in HIV-infected Persons. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 29040163 DOI: 10.1097/Qai.0000000000001573  1
2017 Julg B, Tartaglia LJ, Keele BF, Wagh K, Pegu A, Sok D, Abbink P, Schmidt SD, Wang K, Chen X, Gordon Joyce M, Georgiev IS, Choe M, Kwong PD, Doria-Rose NA, et al. Broadly neutralizing antibodies targeting the HIV-1 envelope V2 apex confer protection against a clade C SHIV challenge. Science Translational Medicine. 9. PMID 28878010 DOI: 10.1126/Scitranslmed.Aal1321  1
2017 Williams LD, Ofek G, Schätzle S, McDaniel JR, Lu X, Nicely NI, Wu L, Lougheed CS, Bradley T, Louder MK, McKee K, Bailer RT, O'Dell S, Georgiev IS, Seaman MS, et al. Potent and broad HIV-neutralizing antibodies in memory B cells and plasma. Science Immunology. 2. PMID 28783671 DOI: 10.1126/Sciimmunol.Aal2200  1
2017 Surdel MC, Horvath DJ, Lojek LJ, Fullen AR, Simpson J, Dutter BF, Salleng KJ, Ford JB, Jenkins JL, Nagarajan R, Teixeira PL, Albertolle M, Georgiev IS, Jansen ED, Sulikowski GA, et al. Antibacterial photosensitization through activation of coproporphyrinogen oxidase. Proceedings of the National Academy of Sciences of the United States of America. PMID 28739897 DOI: 10.1073/Pnas.1700469114  0.01
2017 Cale EM, Gorman J, Radakovich NA, Crooks ET, Osawa K, Tong T, Li J, Nagarajan R, Ozorowski G, Ambrozak DR, Asokan M, Bailer RT, Bennici AK, Chen X, Doria-Rose NA, ... ... Georgiev IS, et al. Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 46: 777-791.e10. PMID 28514685 DOI: 10.1016/J.Immuni.2017.04.011  1
2017 Zhou T, Doria-Rose NA, Cheng C, Stewart-Jones GBE, Chuang GY, Chambers M, Druz A, Geng H, McKee K, Kwon YD, O'Dell S, Sastry M, Schmidt SD, Xu K, Chen L, ... ... Georgiev IS, et al. Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation. Cell Reports. 19: 719-732. PMID 28445724 DOI: 10.1016/J.Celrep.2017.04.013  1
2017 Jain S, Jou JD, Georgiev IS, Donald BR. A critical analysis of computational protein design with sparse residue interaction graphs. Plos Computational Biology. 13: e1005346. PMID 28358804 DOI: 10.1371/Journal.Pcbi.1005346  1
2017 Alam SM, Aussedat B, Vohra Y, Ryan Meyerhoff R, Cale EM, Walkowicz WE, Radakovich NA, Anasti K, Armand L, Parks R, Sutherland L, Scearce R, Joyce MG, Pancera M, Druz A, ... Georgiev IS, et al. Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide. Science Translational Medicine. 9. PMID 28298421 DOI: 10.1126/Scitranslmed.Aai7521  1
2017 Chuang GY, Geng H, Pancera M, Xu K, Cheng C, Acharya P, Chambers M, Druz A, Tsybovsky Y, Wanninger TG, Yang Y, Doria-Rose NA, Georgiev IS, Gorman J, Joyce MG, et al. Structure-Based Design of a Soluble Prefusion-Closed HIV-1-Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. Journal of Virology. PMID 28275193 DOI: 10.1128/Jvi.02268-16  1
2017 Kwong PD, Chuang GY, DeKosky BJ, Gindin T, Georgiev IS, Lemmin T, Schramm CA, Sheng Z, Soto C, Yang AS, Mascola JR, Shapiro L. Antibodyomics: bioinformatics technologies for understanding B-cell immunity to HIV-1. Immunological Reviews. 275: 108-128. PMID 28133812 DOI: 10.1111/Imr.12480  1
2017 Doria-Rose NA, Altae-Tran HR, Roark RS, Schmidt SD, Sutton MS, Louder MK, Chuang GY, Bailer RT, Cortez V, Kong R, McKee K, O'Dell S, Wang F, Abdool Karim SS, Binley JM, ... ... Georgiev IS, et al. Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting. Plos Pathogens. 13: e1006148. PMID 28052137 DOI: 10.1371/Journal.Ppat.1006148  1
2017 Ojewole A, Lowegard A, Gainza P, Reeve SM, Georgiev I, Anderson AC, Donald BR. OSPREY Predicts Resistance Mutations Using Positive and Negative Computational Protein Design. Methods in Molecular Biology (Clifton, N.J.). 1529: 291-306. PMID 27914058 DOI: 10.1007/978-1-4939-6637-0_15  1
2016 Huang J, Kang BH, Ishida E, Zhou T, Griesman T, Sheng Z, Wu F, Doria-Rose NA, Zhang B, McKee K, O'Dell S, Chuang GY, Druz A, Georgiev IS, Schramm CA, et al. Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth. Immunity. 45: 1108-1121. PMID 27851912 DOI: 10.1016/J.Immuni.2016.10.027  1
2016 Longo NS, Sutton MS, Shiakolas AR, Guenaga J, Jarosinski MC, Georgiev IS, McKee K, Bailer RT, Louder MK, O'Dell S, Connors M, Wyatt RT, Mascola JR, Doria-Rose NA. Multiple antibody lineages in one donor target the glycan-V3 supersite of the HIV-1 envelope glycoprotein and display a preference for quaternary binding. Journal of Virology. PMID 27654288 DOI: 10.1128/Jvi.01012-16  1
2016 Tian M, Cheng C, Chen X, Duan H, Cheng HL, Dao M, Sheng Z, Kimble M, Wang L, Lin S, Schmidt SD, Du Z, Joyce MG, Chen Y, DeKosky BJ, ... ... Georgiev IS, et al. Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires. Cell. 166: 1471-1484.e18. PMID 27610571 DOI: 10.1016/J.Cell.2016.07.029  1
2016 Francica JR, Lynn GM, Laga R, Joyce MG, Ruckwardt TJ, Moribito KM, Chen M, Chaudhuri R, Zhang B, Sastry M, Ko K, Choe M, Pechar M, Georgiev IS, Kueltzo LA, et al. Thermo-Responsive Polymer Nanoparticles Co-Deliver RSV F Trimers with a TLR-7/8 Adjuvant. Bioconjugate Chemistry. PMID 27583777 DOI: 10.1021/Acs.Bioconjchem.6B00370  1
2016 Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, et al. Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV. Nature Structural & Molecular Biology. PMID 27478931 DOI: 10.1038/Nsmb.3267  1
2016 Boyington JC, Joyce MG, Sastry M, Stewart-Jones GB, Chen M, Kong WP, Ngwuta JO, Thomas PV, Tsybovsky Y, Yang Y, Zhang B, Chen L, Druz A, Georgiev IS, Ko K, et al. Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus. Plos One. 11: e0159709. PMID 27463224 DOI: 10.1371/Journal.Pone.0159709  1
2016 Joyce MG, Wheatley AK, Thomas PV, Chuang GY, Soto C, Bailer RT, Druz A, Georgiev IS, Gillespie RA, Kanekiyo M, Kong WP, Leung K, Narpala SN, Prabhakaran MS, Yang ES, et al. Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell. PMID 27453470 DOI: 10.1016/J.Cell.2016.06.043  1
2016 Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, ... ... Georgiev IS, et al. Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (New York, N.Y.). 352: 828-33. PMID 27174988 DOI: 10.1126/Science.Aae0474  1
2016 Stewart-Jones GB, Soto C, Lemmin T, Chuang GY, Druz A, Kong R, Thomas PV, Wagh K, Zhou T, Behrens AJ, Bylund T, Choi CW, Davison JR, Georgiev IS, Joyce MG, et al. Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G. Cell. PMID 27114034 DOI: 10.1016/J.Cell.2016.04.010  1
2016 Kwon YD, Georgiev IS, Ofek G, Zhang B, Asokan M, Bailer RT, Bao A, Caruso W, Chen X, Choe M, Druz A, Ko SY, Louder MK, McKee K, O'Dell S, et al. Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. Journal of Virology. PMID 27053554 DOI: 10.1128/Jvi.03246-15  1
2016 Bonsignori M, Zhou T, Sheng Z, Chen L, Gao F, Joyce MG, Ozorowski G, Chuang GY, Schramm CA, Wiehe K, Alam SM, Bradley T, Gladden MA, Hwang KK, Iyengar S, ... ... Georgiev IS, et al. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody. Cell. PMID 26949186 DOI: 10.1016/J.Cell.2016.02.022  1
2016 Jou JD, Jain S, Georgiev IS, Donald BR. BWM*: A Novel, Provable, Ensemble-based Dynamic Programming Algorithm for Sparse Approximations of Computational Protein Design. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. PMID 26744898 DOI: 10.1089/Cmb.2015.0194  1
2015 Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, et al. Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design. Nature Structural & Molecular Biology. PMID 26689967 DOI: 10.1038/Nsmb.3144  1
2015 Pegu A, Asokan M, Wu L, Wang K, Hataye J, Casazza JP, Guo X, Shi W, Georgiev I, Zhou T, Chen X, O'Dell S, Todd JP, Kwong PD, Rao SS, et al. Activation and lysis of human CD4 cells latently infected with HIV-1. Nature Communications. 6: 8447. PMID 26485194 DOI: 10.1038/Ncomms9447  1
2015 Ngwuta JO, Chen M, Modjarrad K, Joyce MG, Kanekiyo M, Kumar A, Yassine HM, Moin SM, Killikelly AM, Chuang GY, Druz A, Georgiev IS, Rundlet EJ, Sastry M, Stewart-Jones GB, et al. Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera. Science Translational Medicine. 7: 309ra162. PMID 26468324 DOI: 10.1126/Scitranslmed.Aac4241  1
2015 Asokan M, Rudicell RS, Louder M, McKee K, O'Dell S, Stewart-Jones G, Wang K, Xu L, Chen X, Choe M, Chuang G, Georgiev IS, Joyce MG, Kirys T, Ko S, et al. Bispecific antibodies targeting different epitopes on the HIV-1 envelope exhibit broad and potent neutralization. Journal of Virology. PMID 26446600 DOI: 10.1128/Jvi.02097-15  1
2015 Cortez V, Wang B, Dingens A, Chen MM, Ronen K, Georgiev IS, McClelland RS, Overbaugh J. The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection. Plos Pathogens. 11: e1004973. PMID 26158467 DOI: 10.1371/Journal.Ppat.1004973  1
2015 Stewart-Jones GB, Thomas PV, Chen M, Druz A, Joyce MG, Kong WP, Sastry M, Soto C, Yang Y, Zhang B, Chen L, Chuang GY, Georgiev IS, McLellan JS, Srivatsan S, et al. A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus. Plos One. 10: e0128779. PMID 26098893 DOI: 10.1371/Journal.Pone.0128779  1
2015 Do Kwon Y, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, et al. Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env. Nature Structural & Molecular Biology. 22: 522-31. PMID 26098315 DOI: 10.1038/Nsmb.3051  1
2015 Saunders KO, Wang L, Joyce MG, Yang ZY, Balazs AB, Cheng C, Ko SY, Kong WP, Rudicell RS, Georgiev IS, Duan L, Foulds KE, Donaldson M, Xu L, Schmidt SD, et al. Broadly neutralizing human immunodeficiency virus type 1 antibody gene transfer protects non-human primates from mucosal simian-human immunodeficiency virus infection. Journal of Virology. PMID 26041300 DOI: 10.1128/Jvi.00908-15  1
2015 Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, Destefano J, O'Dell S, LaBranche C, Robinson JE, et al. Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site. Plos Pathogens. 11: e1004932. PMID 26023780 DOI: 10.1371/Journal.Ppat.1004932  1
2015 Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, ... ... Georgiev IS, et al. Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors. Cell. 161: 1280-92. PMID 26004070 DOI: 10.1016/J.Cell.2015.05.007  1
2015 Wu X, Zhang Z, Schramm CA, Joyce MG, Kwon YD, Zhou T, Sheng Z, Zhang B, O'Dell S, McKee K, Georgiev IS, Chuang GY, Longo NS, Lynch RM, Saunders KO, et al. Maturation and Diversity of the VRC01-Antibody Lineage over 15 Years of Chronic HIV-1 Infection. Cell. 161: 470-85. PMID 25865483 DOI: 10.1016/J.Cell.2015.03.004  1
2015 Chuang GY, Zhang B, McKee K, O'Dell S, Kwon YD, Zhou T, Blinn J, Lloyd K, Parks R, Von Holle T, Ko SY, Kong WP, Pegu A, Wang K, Baruah K, ... ... Georgiev IS, et al. Eliminating antibody polyreactivity through addition of N-linked glycosylation. Protein Science : a Publication of the Protein Society. 24: 1019-30. PMID 25800131 DOI: 10.1002/Pro.2682  1
2015 Saunders KO, Pegu A, Georgiev IS, Zeng M, Joyce MG, Yang ZY, Ko SY, Chen X, Schmidt SD, Haase AT, Todd JP, Bao S, Kwong PD, Rao SS, Mascola JR, et al. Sustained Delivery of a Broadly Neutralizing Antibody in Nonhuman Primates Confers Long-Term Protection against Simian/Human Immunodeficiency Virus Infection. Journal of Virology. 89: 5895-903. PMID 25787288 DOI: 10.1128/Jvi.00210-15  1
2015 Georgiev IS, Joyce MG, Yang Y, Sastry M, Zhang B, Baxa U, Chen RE, Druz A, Lees CR, Narpala S, Schön A, Van Galen J, Chuang GY, Gorman J, Harned A, et al. Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env. Journal of Virology. 89: 5318-29. PMID 25740988 DOI: 10.1128/Jvi.03451-14  1
2015 Edlefsen PT, Rolland M, Hertz T, Tovanabutra S, Gartland AJ, deCamp AC, Magaret CA, Ahmed H, Gottardo R, Juraska M, McCoy C, Larsen BB, Sanders-Buell E, Carrico C, Menis S, ... ... Georgiev IS, et al. Comprehensive sieve analysis of breakthrough HIV-1 sequences in the RV144 vaccine efficacy trial. Plos Computational Biology. 11: e1003973. PMID 25646817 DOI: 10.1371/Journal.Pcbi.1003973  1
2015 Reeve SM, Gainza P, Frey KM, Georgiev I, Donald BR, Anderson AC. Protein design algorithms predict viable resistance to an experimental antifolate. Proceedings of the National Academy of Sciences of the United States of America. 112: 749-54. PMID 25552560 DOI: 10.1073/Pnas.1411548112  1
2015 Fong Y, Datta S, Georgiev IS, Kwong PD, Tomaras GD. Kernel-based logistic regression model for protein sequence without vectorialization. Biostatistics (Oxford, England). 16: 480-92. PMID 25532524 DOI: 10.1093/Biostatistics/Kxu056  1
2015 Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, DeStefano J, O’Dell S, LaBranche C, Robinson JE, et al. Potent vaccine sera target epitopes that overlap the CD4 binding site. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004932.G005  1
2015 Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, DeStefano J, O’Dell S, LaBranche C, Robinson JE, et al. Serum recognition of the native trimer and effects of a key mutation in the CD4 binding loop. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004932.G003  1
2015 Crooks ET, Tong T, Chakrabarti B, Narayan K, Georgiev IS, Menis S, Huang X, Kulp D, Osawa K, Muranaka J, Stewart-Jones G, DeStefano J, O’Dell S, LaBranche C, Robinson JE, et al. Overview of human plasmas and animal sera. Plos Pathogens. DOI: 10.1371/Journal.Ppat.1004932.G001  1
2015 Acharya P, Luongo TS, Georgiev IS, Matz J, Schmidt SD, Louder MK, Kessler P, Yang Y, McKee K, O'Dell S, Chen L, Baty D, Chames P, Martin L, Mascola JR, et al. Correction to Heavy Chain-Only IgG2b Llama antibody effects Near-Pan HIV-1 neutralization by recognizing a CD4-induced epitope that includes elements of coreceptor- and CD4-binding sites [Journal of Virology 87, 18, (2013) 10173-10181] Journal of Virology. 89: 883-885. DOI: 10.1128/Jvi.02621-14  1
2015 Jou JD, Jain S, Georgiev I, Donald BR. BWM∗: A novel, provable, ensemble-based dynamic programming algorithm for sparse approximations of computational protein design Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 9029: 154-166. DOI: 10.1007/978-3-319-16706-0_16  1
2014 Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang GY, Ofek G, Stewart-Jones GB, Stuckey J, Bailer RT, Joyce MG, Louder MK, et al. Structure and immune recognition of trimeric pre-fusion HIV-1 Env. Nature. 514: 455-61. PMID 25296255 DOI: 10.1038/Nature13808  1
2014 Kepler TB, Liao HX, Alam SM, Bhaskarabhatla R, Zhang R, Yandava C, Stewart S, Anasti K, Kelsoe G, Parks R, Lloyd KE, Stolarchuk C, Pritchett J, Solomon E, Friberg E, ... ... Georgiev IS, et al. Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies. Cell Host & Microbe. 16: 304-13. PMID 25211073 DOI: 10.1016/J.Chom.2014.08.006  1
2014 Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Imamichi H, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, et al. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface. Nature. 515: 138-42. PMID 25186731 DOI: 10.1038/Nature13601  1
2014 Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, et al. Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo. Journal of Virology. 88: 12669-82. PMID 25142607 DOI: 10.1128/Jvi.02213-14  1
2014 Chuang GY, Liou D, Kwong PD, Georgiev IS. NEP: web server for epitope prediction based on antibody neutralization of viral strains with diverse sequences. Nucleic Acids Research. 42: W64-71. PMID 24782517 DOI: 10.1093/Nar/Gku318  1
2014 Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, et al. Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature. 509: 55-62. PMID 24590074 DOI: 10.1038/Nature13036  1
2014 Georgiev IS, Rudicell RS, Saunders KO, Shi W, Kirys T, McKee K, O'Dell S, Chuang GY, Yang ZY, Ofek G, Connors M, Mascola JR, Nabel GJ, Kwong PD. Antibodies VRC01 and 10E8 neutralize HIV-1 with high breadth and potency even with Ig-framework regions substantially reverted to germline. Journal of Immunology (Baltimore, Md. : 1950). 192: 1100-6. PMID 24391217 DOI: 10.4049/Jimmunol.1302515  1
2014 Ofek G, Zirkle B, Yang Y, Zhu Z, McKee K, Zhang B, Chuang GY, Georgiev IS, O'Dell S, Doria-Rose N, Mascola JR, Dimitrov DS, Kwong PD. Structural basis for HIV-1 neutralization by 2F5-like antibodies m66 and m66.6. Journal of Virology. 88: 2426-41. PMID 24335316 DOI: 10.1128/Jvi.02837-13  1
2014 Lynch RM, Yamamoto T, Wong P, Georgiev I, Matus-Nicodemos R, Schmidt S, Gautam R, Sheng Z, Shapiro L, Nishimura Y, Martin MA, Mascola JR, Koup RA. Isolation of Monoclonal Antibodies from a SHIV-AD8 Infected Rhesus Macaque with Broad Neutralizing Activity Aids Research and Human Retroviruses. 30. DOI: 10.1089/Aid.2014.5145.Abstract  1
2013 Georgiev IS, Gordon Joyce M, Zhou T, Kwong PD. Elicitation of HIV-1-neutralizing antibodies against the CD4-binding site. Current Opinion in Hiv and Aids. 8: 382-92. PMID 23924998 DOI: 10.1097/Coh.0B013E328363A90E  1
2013 Zhou T, Zhu J, Wu X, Moquin S, Zhang B, Acharya P, Georgiev IS, Altae-Tran HR, Chuang GY, Joyce MG, Do Kwon Y, Longo NS, Louder MK, Luongo T, McKee K, et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies. Immunity. 39: 245-58. PMID 23911655 DOI: 10.1016/J.Immuni.2013.04.012  1
2013 Chuang GY, Acharya P, Schmidt SD, Yang Y, Louder MK, Zhou T, Kwon YD, Pancera M, Bailer RT, Doria-Rose NA, Nussenzweig MC, Mascola JR, Kwong PD, Georgiev IS. Residue-level prediction of HIV-1 antibody epitopes based on neutralization of diverse viral strains. Journal of Virology. 87: 10047-58. PMID 23843642 DOI: 10.1128/Jvi.00984-13  1
2013 Acharya P, Luongo TS, Georgiev IS, Matz J, Schmidt SD, Louder MK, Kessler P, Yang Y, McKee K, O'Dell S, Chen L, Baty D, Chames P, Martin L, Mascola JR, et al. Heavy chain-only IgG2b llama antibody effects near-pan HIV-1 neutralization by recognizing a CD4-induced epitope that includes elements of coreceptor- and CD4-binding sites. Journal of Virology. 87: 10173-81. PMID 23843638 DOI: 10.1128/Jvi.01332-13  1
2013 Georgiev IS, Doria-Rose NA, Zhou T, Kwon YD, Staupe RP, Moquin S, Chuang GY, Louder MK, Schmidt SD, Altae-Tran HR, Bailer RT, McKee K, Nason M, O'Dell S, Ofek G, et al. Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science (New York, N.Y.). 340: 751-6. PMID 23661761 DOI: 10.1126/Science.1233989  1
2013 Klein F, Diskin R, Scheid JF, Gaebler C, Mouquet H, Georgiev IS, Pancera M, Zhou T, Incesu RB, Fu BZ, Gnanapragasam PN, Oliveira TY, Seaman MS, Kwong PD, Bjorkman PJ, et al. Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell. 153: 126-38. PMID 23540694 DOI: 10.1016/J.Cell.2013.03.018  1
2013 Gainza P, Roberts KE, Georgiev I, Lilien RH, Keedy DA, Chen CY, Reza F, Anderson AC, Richardson DC, Richardson JS, Donald BR. OSPREY: protein design with ensembles, flexibility, and provable algorithms. Methods in Enzymology. 523: 87-107. PMID 23422427 DOI: 10.1016/B978-0-12-394292-0.00005-9  1
2012 Rolland M, Edlefsen PT, Larsen BB, Tovanabutra S, Sanders-Buell E, Hertz T, deCamp AC, Carrico C, Menis S, Magaret CA, Ahmed H, Juraska M, Chen L, Konopa P, Nariya S, ... ... Georgiev I, et al. Increased HIV-1 vaccine efficacy against viruses with genetic signatures in Env V2. Nature. 490: 417-20. PMID 22960785 DOI: 10.1038/Nature11519  1
2012 Kong R, Li H, Georgiev I, Changela A, Bibollet-Ruche F, Decker JM, Rowland-Jones SL, Jaye A, Guan Y, Lewis GK, Langedijk JP, Hahn BH, Kwong PD, Robinson JE, Shaw GM. Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies. Journal of Virology. 86: 12115-28. PMID 22933274 DOI: 10.1128/Jvi.01632-12  1
2012 Keedy DA, Georgiev I, Triplett EB, Donald BR, Richardson DC, Richardson JS. The role of local backrub motions in evolved and designed mutations. Plos Computational Biology. 8: e1002629. PMID 22876172 DOI: 10.1371/Journal.Pcbi.1002629  1
2012 Chuang GY, Boyington JC, Joyce MG, Zhu J, Nabel GJ, Kwong PD, Georgiev I. Computational prediction of N-linked glycosylation incorporating structural properties and patterns. Bioinformatics (Oxford, England). 28: 2249-55. PMID 22782545 DOI: 10.1093/Bioinformatics/Bts426  1
2012 Bar KJ, Tsao CY, Iyer SS, Decker JM, Yang Y, Bonsignori M, Chen X, Hwang KK, Montefiori DC, Liao HX, Hraber P, Fischer W, Li H, Wang S, Sterrett S, ... ... Georgiev I, et al. Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape. Plos Pathogens. 8: e1002721. PMID 22693447 DOI: 10.1371/Journal.Ppat.1002721  1
2012 Doria-Rose NA, Georgiev I, O'Dell S, Chuang GY, Staupe RP, McLellan JS, Gorman J, Pancera M, Bonsignori M, Haynes BF, Burton DR, Koff WC, Kwong PD, Mascola JR. A short segment of the HIV-1 gp120 V1/V2 region is a major determinant of resistance to V1/V2 neutralizing antibodies. Journal of Virology. 86: 8319-23. PMID 22623764 DOI: 10.1128/Jvi.00696-12  1
2012 Hansman GS, Taylor DW, McLellan JS, Smith TJ, Georgiev I, Tame JR, Park SY, Yamazaki M, Gondaira F, Miki M, Katayama K, Murata K, Kwong PD. Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle. Journal of Virology. 86: 3635-46. PMID 22278249 DOI: 10.1128/Jvi.06868-11  1
2012 Kong R, Li H, Bibollet-Ruche F, Decker JM, Zheng NN, Gottlieb GS, Kiviat NB, Sow PS, Georgiev I, Hahn BH, Kwong PD, Robinson JE, Shaw GM. Broad and potent neutralizing antibody responses elicited in natural HIV-2 infection. Journal of Virology. 86: 947-60. PMID 22031948 DOI: 10.1128/Jvi.06155-11  1
2012 Hansman GS, Shahzad-Ul-Hussan S, McLellan JS, Chuang GY, Georgiev I, Shimoike T, Katayama K, Bewley CA, Kwong PD. Structural basis for norovirus inhibition and fucose mimicry by citrate. Journal of Virology. 86: 284-92. PMID 22031945 DOI: 10.1128/Jvi.05909-11  1
2012 Georgiev I, Acharya P, Schmidt S, Li Y, Wycuff D, Ofek G, Doria-Rose N, Luongo T, Yang Y, Zhou T, Donald B, Mascola J, Kwong P. Design of epitope-specific probes for sera analysis and antibody isolation. Retrovirology. 9: 50. DOI: 10.1186/1742-4690-9-S2-P50  1
2012 Dai K, Boyington J, Shi W, Schmidt S, Georgiev I, Lingwood D, Kwong P, Mascola J, Yang Z, Nabel G. Hyperglycosylated resurfaced stabilized GP120 core as an immunogen elicits antibodies targeted at the CD4-binding site. Retrovirology. 9: 23. DOI: 10.1186/1742-4690-9-S2-P23  1
2011 McLellan JS, Pancera M, Carrico C, Gorman J, Julien JP, Khayat R, Louder R, Pejchal R, Sastry M, Dai K, O'Dell S, Patel N, Shahzad-ul-Hussan S, Yang Y, Zhang B, ... ... Georgiev I, et al. Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9. Nature. 480: 336-43. PMID 22113616 DOI: 10.1038/Nature10696  1
2011 Wu X, Zhou T, Zhu J, Zhang B, Georgiev I, Wang C, Chen X, Longo NS, Louder M, McKee K, O'Dell S, Perfetto S, Schmidt SD, Shi W, Wu L, et al. Focused evolution of HIV-1 neutralizing antibodies revealed by structures and deep sequencing. Science (New York, N.Y.). 333: 1593-602. PMID 21835983 DOI: 10.1126/science.1207532  1
2011 Sastry M, Xu L, Georgiev IS, Bewley CA, Nabel GJ, Kwong PD. Mammalian production of an isotopically enriched outer domain of the HIV-1 gp120 glycoprotein for NMR spectroscopy. Journal of Biomolecular Nmr. 50: 197-207. PMID 21667299 DOI: 10.1007/S10858-011-9506-4  1
2011 Hansman GS, Biertümpfel C, Georgiev I, McLellan JS, Chen L, Zhou T, Katayama K, Kwong PD. Crystal structures of GII.10 and GII.12 norovirus protruding domains in complex with histo-blood group antigens reveal details for a potential site of vulnerability. Journal of Virology. 85: 6687-701. PMID 21525337 DOI: 10.1128/Jvi.00246-11  1
2010 Frey KM, Georgiev I, Donald BR, Anderson AC. Predicting resistance mutations using protein design algorithms. Proceedings of the National Academy of Sciences of the United States of America. 107: 13707-12. PMID 20643959 DOI: 10.1073/Pnas.1002162107  1
2010 Zhou T, Georgiev I, Wu X, Yang ZY, Dai K, Finzi A, Kwon YD, Scheid JF, Shi W, Xu L, Yang Y, Zhu J, Nussenzweig MC, Sodroski J, Shapiro L, et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science (New York, N.Y.). 329: 811-7. PMID 20616231 DOI: 10.1126/Science.1192819  1
2009 Chen CY, Georgiev I, Anderson AC, Donald BR. Computational structure-based redesign of enzyme activity. Proceedings of the National Academy of Sciences of the United States of America. 106: 3764-9. PMID 19228942 DOI: 10.1073/Pnas.0900266106  1
2008 Georgiev I, Keedy D, Richardson JS, Richardson DC, Donald BR. Algorithm for backrub motions in protein design. Bioinformatics (Oxford, England). 24: i196-204. PMID 18586714 DOI: 10.1093/bioinformatics/btn169  1
2008 Georgiev I, Lilien RH, Donald BR. The minimized dead-end elimination criterion and its application to protein redesign in a hybrid scoring and search algorithm for computing partition functions over molecular ensembles. Journal of Computational Chemistry. 29: 1527-42. PMID 18293294 DOI: 10.1002/Jcc.20909  1
2007 Georgiev I, Donald BR. Dead-end elimination with backbone flexibility. Bioinformatics (Oxford, England). 23: i185-94. PMID 17646295 DOI: 10.1093/bioinformatics/btm197  1
2006 Stevens BW, Lilien RH, Georgiev I, Donald BR, Anderson AC. Redesigning the PheA domain of gramicidin synthetase leads to a new understanding of the enzyme's mechanism and selectivity. Biochemistry. 45: 15495-504. PMID 17176071 DOI: 10.1021/Bi061788M  1
2006 Georgiev I, Lilien RH, Donald BR. Improved Pruning algorithms and Divide-and-Conquer strategies for Dead-End Elimination, with application to protein design. Bioinformatics (Oxford, England). 22: e174-83. PMID 16873469 DOI: 10.1093/Bioinformatics/Btl220  1
2006 Georgiev I, Lilien RH, Donald BR. A novel minimized dead-end elimination criterion and its application to protein redesign in a hybrid scoring and search algorithm for computing partition functions over molecular ensembles Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 3909: 530-545. DOI: 10.1007/11732990_44  1
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