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Alberto Serrano-Pozo, MD PhD - Publications

Affiliations: 
2008-2013 Neurology Massachusetts General Hospital, Boston, MA 
 2013-2017 Neurology University of Iowa Hospitals & Clinics, Iowa City, IA, United States 
 2017- Neurology Massachusetts General Hospital, Boston, MA 
Area:
Alzheimer's disease, Lewy body disease, Frontotemporal Lobar Degenerations, Vascular dementias, Neurology
Website:
https://www.serranopozolab.org
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Das S, Li Z, Noori A, Hyman BT, Serrano-Pozo A. Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration. Journal of Neuroinflammation. 17: 227. PMID 32736565 DOI: 10.1186/S12974-020-01898-Y  0.722
2020 Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, ... ... Serrano-Pozo A, et al. Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease. Nature Medicine. PMID 32572268 DOI: 10.1038/S41591-020-0938-9  0.793
2020 Calvo-Rodriguez M, Hou SS, Snyder AC, Kharitonova EK, Russ AN, Das S, Fan Z, Muzikansky A, Garcia-Alloza M, Serrano-Pozo A, Hudry E, Bacskai BJ. Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer's disease. Nature Communications. 11: 2146. PMID 32358564 DOI: 10.1038/S41467-020-16074-2  0.656
2019 Serrano-Pozo A, Growdon JH. Is Alzheimer's Disease Risk Modifiable? Journal of Alzheimer's Disease : Jad. 67: 795-819. PMID 30776012 DOI: 10.3233/Jad181028  0.581
2019 Pérez-Nievas BG, Serrano-Pozo A. Editorial: The Role of Glia in Alzheimer's Disease. Frontiers in Neurology. 9: 1161. PMID 30692961 DOI: 10.3389/Fneur.2018.01161  0.556
2018 Perez-Nievas BG, Serrano-Pozo A. Deciphering the Astrocyte Reaction in Alzheimer's Disease. Frontiers in Aging Neuroscience. 10: 114-114. PMID 29922147 DOI: 10.3389/Fnagi.2018.00114  0.612
2017 Serrano-Pozo A, Aldridge GM, Zhang Q. Four Decades of Research in Alzheimer's Disease (1975-2014): A Bibliometric and Scientometric Analysis. Journal of Alzheimer's Disease : Jad. PMID 28671119 DOI: 10.3233/Jad-170184  0.442
2017 Serrano-Pozo A, Sánchez-García MA, Heras-Garvín A, March-Díaz R, Navarro V, Vizuete M, López-Barneo J, Vitorica J, Pascual A. Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo. Plos One. 12: e0170345. PMID 28099462 DOI: 10.1371/Journal.Pone.0170345  0.504
2016 Serrano-Pozo A, Qian J, Muzikansky A, Monsell SE, Montine TJ, Frosch MP, Betensky RA, Hyman BT. Thal Amyloid Stages Do Not Significantly Impact the Correlation Between Neuropathological Change and Cognition in the Alzheimer Disease Continuum. Journal of Neuropathology and Experimental Neurology. PMID 27105663 DOI: 10.1093/Jnen/Nlw026  0.685
2015 Serrano-Pozo A, Betensky RA, Frosch MP, Hyman BT. Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease. The American Journal of Pathology. PMID 26687817 DOI: 10.1016/J.Ajpath.2015.10.010  0.672
2015 Serrano-Pozo A, Hyman BT. Alzheimer Disease: Alzheimer dementia with sparse amyloid-AD mimic or variant? Nature Reviews. Neurology. PMID 26553593 DOI: 10.1038/Nrneurol.2015.221  0.704
2015 Bachhuber T, Katzmarski N, McCarter JF, Loreth D, Tahirovic S, Kamp F, Abou-Ajram C, Nuscher B, Serrano-Pozo A, Müller A, Prinz M, Steiner H, Hyman BT, Haass C, Meyer-Luehmann M. Inhibition of amyloid-β plaque formation by α-synuclein. Nature Medicine. 21: 802-7. PMID 26099047 DOI: 10.1038/Nm.3885  0.639
2015 von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). Plos One. 10: e0129047. PMID 26053850 DOI: 10.1371/Journal.Pone.0129047  0.601
2015 Serrano-Pozo A, Qian J, Monsell SE, Betensky RA, Hyman BT. APOEε2 is associated with milder clinical and pathological Alzheimer disease. Annals of Neurology. 77: 917-29. PMID 25623662 DOI: 10.1002/Ana.24369  0.734
2014 Crary JF, Trojanowski JQ, Schneider JA, Abisambra JF, Abner EL, Alafuzoff I, Arnold SE, Attems J, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Gearing M, Grinberg LT, Hof PR, ... ... Serrano-Pozo A, et al. Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathologica. 128: 755-66. PMID 25348064 DOI: 10.1007/S00401-014-1349-0  0.682
2014 Serrano-Pozo A, Qian J, Monsell SE, Blacker D, Gómez-Isla T, Betensky RA, Growdon JH, Johnson KA, Frosch MP, Sperling RA, Hyman BT. Mild to moderate Alzheimer dementia with insufficient neuropathological changes. Annals of Neurology. 75: 597-601. PMID 24585367 DOI: 10.1002/Ana.24125  0.727
2014 Suárez-González A, Serrano-Pozo A, Arroyo-Anlló EM, Franco-Macías E, Polo J, García-Solís D, Gil-Néciga E. Utility of neuropsychiatric tools in the differential diagnosis of dementia with Lewy bodies and Alzheimer's disease: quantitative and qualitative findings. International Psychogeriatrics. 26: 453-61. PMID 24284139 DOI: 10.1017/S1041610213002068  0.787
2013 Serrano-Pozo A, Qian J, Monsell SE, Frosch MP, Betensky RA, Hyman BT. Examination of the clinicopathologic continuum of Alzheimer disease in the autopsy cohort of the National Alzheimer Coordinating Center. Journal of Neuropathology and Experimental Neurology. 72: 1182-92. PMID 24226270 DOI: 10.1097/Nen.0000000000000016  0.727
2013 Xie H, Guan J, Borrelli LA, Xu J, Serrano-Pozo A, Bacskai BJ. Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17042-51. PMID 24155308 DOI: 10.1523/Jneurosci.1836-13.2013  0.578
2013 Maguire CA, Crommentuijn MH, Mu D, Hudry E, Serrano-Pozo A, Hyman BT, Tannous BA. Mouse gender influences brain transduction by intravascularly administered AAV9. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 1470-1. PMID 23903572 DOI: 10.1038/Mt.2013.95  0.492
2013 Perez-Nievas BG, Stein TD, Tai HC, Dols-Icardo O, Scotton TC, Barroeta-Espar I, Fernandez-Carballo L, de Munain EL, Perez J, Marquie M, Serrano-Pozo A, Frosch MP, Lowe V, Parisi JE, Petersen RC, et al. Dissecting phenotypic traits linked to human resilience to Alzheimer's pathology. Brain : a Journal of Neurology. 136: 2510-26. PMID 23824488 DOI: 10.1093/Brain/Awt171  0.702
2013 Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TL. Studying synapses in human brain with array tomography and electron microscopy. Nature Protocols. 8: 1366-80. PMID 23787894 DOI: 10.1038/Nprot.2013.078  0.652
2013 Serrano-Pozo A, Muzikansky A, Gómez-Isla T, Growdon JH, Betensky RA, Frosch MP, Hyman BT. Differential relationships of reactive astrocytes and microglia to fibrillar amyloid deposits in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 72: 462-71. PMID 23656989 DOI: 10.1097/Nen.0B013E3182933788  0.662
2013 Griciuc A, Serrano-Pozo A, Parrado AR, Lesinski AN, Asselin CN, Mullin K, Hooli B, Choi SH, Hyman BT, Tanzi RE. Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta. Neuron. 78: 631-43. PMID 23623698 DOI: 10.1016/J.Neuron.2013.04.014  0.592
2013 Serrano-Pozo A, Gómez-Isla T, Growdon JH, Frosch MP, Hyman BT. A phenotypic change but not proliferation underlies glial responses in Alzheimer disease. The American Journal of Pathology. 182: 2332-44. PMID 23602650 DOI: 10.1016/J.Ajpath.2013.02.031  0.67
2013 Wahlster L, Arimon M, Nasser-Ghodsi N, Post KL, Serrano-Pozo A, Uemura K, Berezovska O. Presenilin-1 adopts pathogenic conformation in normal aging and in sporadic Alzheimer's disease. Acta Neuropathologica. 125: 187-99. PMID 23138650 DOI: 10.1007/S00401-012-1065-6  0.603
2013 Bachhuber T, McCarter J, Tahirovic S, Nuscher B, Kamp F, Abou-Ajram C, Serrano-Pozo A, Hyman B, Haass C, Meyer-Luehmann M. Cross-inhibition of beta-amyloid plaque formation by alpha-synuclein Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.05.1398  0.521
2012 Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, Mitani A, Joyner D, Thyssen DH, Bacskai BJ, Frosch MP, Spires-Jones TL, Finn MB, Holtzman DM, Hyman BT. Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15181-92. PMID 23100439 DOI: 10.1523/Jneurosci.1542-12.2012  0.795
2012 Tai HC, Serrano-Pozo A, Hashimoto T, Frosch MP, Spires-Jones TL, Hyman BT. The synaptic accumulation of hyperphosphorylated tau oligomers in Alzheimer disease is associated with dysfunction of the ubiquitin-proteasome system. The American Journal of Pathology. 181: 1426-35. PMID 22867711 DOI: 10.1016/J.Ajpath.2012.06.033  0.79
2012 Serrano-Pozo A, Mielke ML, Muzitansky A, Gómez-Isla T, Growdon JH, Bacskai BJ, Betensky RA, Frosch MP, Hyman BT. Stable size distribution of amyloid plaques over the course of Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 71: 694-701. PMID 22805771 DOI: 10.1097/Nen.0B013E31825E77De  0.665
2012 Koffie RM, Hashimoto T, Tai HC, Kay KR, Serrano-Pozo A, Joyner D, Hou S, Kopeikina KJ, Frosch MP, Lee VM, Holtzman DM, Hyman BT, Spires-Jones TL. Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-β. Brain : a Journal of Neurology. 135: 2155-68. PMID 22637583 DOI: 10.1093/Brain/Aws127  0.787
2011 Serrano-Pozo A, Frosch MP, Masliah E, Hyman BT. Neuropathological alterations in Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 1: a006189. PMID 22229116 DOI: 10.1101/Cshperspect.A006189  0.699
2011 Serrano-Pozo A, Mielke ML, Gómez-Isla T, Betensky RA, Growdon JH, Frosch MP, Hyman BT. Reactive glia not only associates with plaques but also parallels tangles in Alzheimer's disease. The American Journal of Pathology. 179: 1373-84. PMID 21777559 DOI: 10.1016/J.Ajpath.2011.05.047  0.697
2011 DaRocha-Souto B, Scotton TC, Coma M, Serrano-Pozo A, Hashimoto T, Serenó L, Rodríguez M, Sánchez B, Hyman BT, Gómez-Isla T. Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice. Journal of Neuropathology and Experimental Neurology. 70: 360-76. PMID 21487307 DOI: 10.1097/Nen.0B013E318217A118  0.746
2011 Wahlster L, Arimon M, Nasser-Ghodsi N, Serrano-Pozo A, Hyman B, Berezovska O. γ-Secretase conformational changes in the Alzheimer's Disease brain Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1636  0.618
2010 Serrano-Pozo A, Vega GL, Lütjohann D, Locascio JJ, Tennis MK, Deng A, Atri A, Hyman BT, Irizarry MC, Growdon JH. Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers. Alzheimer Disease and Associated Disorders. 24: 220-6. PMID 20473136 DOI: 10.1097/Wad.0B013E3181D61Fea  0.654
2010 Serrano-Pozo A, William CM, Ferrer I, Uro-Coste E, Delisle MB, Maurage CA, Hock C, Nitsch RM, Masliah E, Growdon JH, Frosch MP, Hyman BT. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a Journal of Neurology. 133: 1312-27. PMID 20360050 DOI: 10.1093/Brain/Awq056  0.623
2007 Pérez PG, Serrano-Pozo A, Franco-Macías E, Montes-Latorre E, Gómez-Aranda F, Campos T. Vincristine-induced acute neurotoxicity versus Guillain-Barré syndrome: a diagnostic dilemma. European Journal of Neurology. 14: 826-828. PMID 17594344 DOI: 10.1111/J.1468-1331.2007.01842.X  0.339
2006 Serrano-Pozo A, Carrillo-García F, Montes-Latorre E, Gómez-Aranda F. Neuralgia amiotrófica bilateral precipitada por infección por el parvovirus B19 Medicina Clinica. 127: 398-398. PMID 16987488 DOI: 10.1157/13092441  0.283
2005 Serrano-Pozo A, Sanz-Fernández G, Martínez-Fernández E, Nevado-Portero J. Spinal anterior artery territory infarction simulating an acute myocardial infarction Journal of Neurology, Neurosurgery, and Psychiatry. 76: 1584-1584. PMID 16227557 DOI: 10.1136/Jnnp.2004.062455  0.301
2004 Serrano-Pozo A, Gómez-Aranda F, Giles M, Chinchón D, Chinchón I, Bautista-Lorite J. Sensory polyneuropathy as initial manifestation of endemic leprosy in Spain. European Neurology. 52: 256-8. PMID 15583462 DOI: 10.1159/000082374  0.298
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